|
Name |
Accession |
Description |
Interval |
E-value |
| OMP_RagA_SusC |
TIGR04056 |
TonB-linked outer membrane protein, SusC/RagA family; This model describes a distinctive clade ... |
110-1089 |
0e+00 |
|
TonB-linked outer membrane protein, SusC/RagA family; This model describes a distinctive clade among the TonB-linked outer membrane proteins (OMP). Members of this family are restricted to the Bacteriodetes lineage (except for Gemmatimonas aurantiaca T-27 from the novel phylum Gemmatimonadetes) and occur in high copy numbers, with over 100 members from Bacteroides thetaiotaomicron VPI-5482 alone. Published descriptions of members of this family are available for RagA from Porphyromonas gingivalis, SusC from Bacteroides thetaiotaomicron, and OmpW from Bacteroides caccae. Members form pairs with members of the SusD/RagB family (pfam07980). Transporter complexes including these outer membrane proteins are likely to import large degradation products of proteins (e.g. RagA) or carbohydrates (e.g. SusC) as nutrients, rather than siderophores. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 274948 [Multi-domain] Cd Length: 981 Bit Score: 801.81 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 110 KKITGVVLDAFG-PVVGANIVEKGTMNGVISDSEGRFVLNVAPGATLIVSYIGYVSQEIKINDQASYTITLREDTETLEE 188
Cdd:TIGR04056 1 ITVTGVVVDETGePLIGASVVVKGTTNGTITDIDGNFSLKVPPGAVLVFSYIGYKTQEVKVKGQKNLNITLKEDTQELDE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 189 VVVVGYGTMKKKDLTGAVKRVNLEESPAVANTSLSQALVGSTAGVNTAQ-SGYAGEDVSLSIRGTTSFSASQNPLIVLDG 267
Cdd:TIGR04056 81 VVVVGYGTQKKKSLTGAVSTVKAKELKKVPVSNLSNALQGKVAGVIITQsSGEPGGDAEIWIRGISSFGGNNSPLYVIDG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 268 IIYNGAMSDINVNDISSIDILKDASAAAVYGARSANGVILITTKKGKTEKPKVSFNMSIGTQSASNHSaNYMNAEEYtrr 347
Cdd:TIGR04056 161 VPRDNGLSDLNPEDIESISVLKDASATAIYGSRGANGVILITTKRGKEGKPKISYNAEFGFSTPTRLP-EMLNAYEY--- 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 348 lADYAYQQdlrawyktnptsdvgrpaypdLSSREANAYYLRSQEEKDSYLSGAAYD----IDWIDKVM-QTGLTQDYNIG 422
Cdd:TIGR04056 237 -AELYNEA---------------------LLNRGSSPPDIYTDEEIEAYRNGLDPDlypnTDWQDEIFkRTAFNQRHNLS 294
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 423 VSGSSDYVNYYLSGAYHDEEGLLLNDQFKRYTFNAKVDTKVTDWLKIGANINFSHRDYSGVSANFD-------YATKASP 495
Cdd:TIGR04056 295 VSGGTEKARYYVSLGYYNEEGILKNSDYKRYNFRANIDAKLTKTLKLSLNVSGSLSKYNNPGGSTSniwgalmLFPRGTP 374
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 496 LAAYDFDTPGYHRLELATESSMKDPLQYLAIDNSDLRNTLFLTlNGRIDVPFIKGLSYDFNYSTTRYHRDNNSFYPSD-- 573
Cdd:TIGR04056 375 YSTPPVYSDGYYPAYNSGNTSLQNPYALLNRGYNENERNRLNG-NASLEQKITKGLKLKGTFSYDYSNYKNKKYYKNPyy 453
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 574 -VDGGFINNGKAIKEPENENAYLFNHIFAYQRTFGDHSLNATFVYTKEKRWGDKTTAIAESFDTDNLGynnlgiGTLFTE 652
Cdd:TIGR04056 454 yNATGGANNGYYSESNSRSRNYYLEATLNYNRTFGKHNVSALLGYSQQENKSSSYGGLLDDLPSLDAG------TSDASV 527
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 653 KSTAWQESNVGLMGRISYNYKNRYLFTGTVRRDGFSGFGSNNKFVTLPSASIGWVISEEDFnpFEDV-----YLKLRLSY 727
Cdd:TIGR04056 528 SGSDSEYRLQSLFGRATYSYKDRYLLEFNFRYDGSSRFAKGNRWGFFPSVSLGWRISEEKF--MKKLkkwlsFLKLRASY 605
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 728 GQNGNQGIG-RYASLAKLGMGAYNY-----DDDRVISLYPSEMANKDLKWERTSSWNFGIDFGFFNQRLNGSFEVYKSHT 801
Cdd:TIGR04056 606 GIVGNDNIGdRYPYLSLYNLGDGGYnfgtnNGTSVTGITESRYGNPNLKWEKTKKWNLGLDLGFFNNRLSLTVDYYYKKT 685
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 802 TDVLVKRTLPNVTGYSWVWANLGGVDNKGVEVELNSVNIQNKNFSWTSGFTFSLNRDKITDLygDGTTQDLTNGWF---V 878
Cdd:TIGR04056 686 KDILQSRSLPSVTGYSSPYANIGKVKNKGVELSLNYRNKIGKDFSWSVRGNFTYNKNKILEL--DEGAYLPVKYPYiskE 763
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 879 GESIGAIYSYEMQGVWQEEDlySGKIYEGWY-PGQQKFADLNGDGKIDaEHDRKIIGNKN-PNCRFSFSNTLTWKNWSLY 956
Cdd:TIGR04056 764 GGPIGQIYGYIADGLFKDDD--SPKQTFGNVrPGDIKYKDVNGDGKID-DDDRVPIGYSNtPDLTYGFGNSFSYKGFDLS 840
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 957 FMLNSMLGGGGYYMGGNGLLAPDNSSDYVVrlnQPAIREYWTPENHSNEGLALFRNQPISTSIYQ-------NRGFVRLQ 1029
Cdd:TIGR04056 841 ALFQGSGGGDVFNDGRGFYPFNGGDWGNVL---KIVADNRWTPENPNADYPRLSYGDSNNSNNYQastrwleDGSYLRLK 917
|
970 980 990 1000 1010 1020
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2486183734 1030 DVSLMYSFDKKLLQKTGvISQLQLFLTGKNLYTFTGWDGWDPE-----YTAFPLTRSLQFGIKLS 1089
Cdd:TIGR04056 918 NLTLGYTLPKKWLKKIG-ISNLRVYFSGQNLFTFSKYKGWDPElqgndGGAYPLQRTFSFGVNLT 981
|
|
| CirA |
COG1629 |
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism]; |
186-926 |
2.91e-52 |
|
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];
Pssm-ID: 441236 [Multi-domain] Cd Length: 644 Bit Score: 195.05 E-value: 2.91e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 186 LEEVVVVGYGT-MKKKDLTGAVKRVNLEESPAVANTSLSQALvGSTAGVNTAQSGyaGEDVSLSIRGTTSfsASQNPLIV 264
Cdd:COG1629 1 LEEVVVTATRTdESLQDVPGSVSVISREQLEDQPATDLGDLL-RRVPGVSVTSAG--GGAGQISIRGFGG--GGNRVLVL 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 265 LDGIIYN------GAMSDINVNDISSIDILKDASAAaVYGARSANGVILITTKKGKTEkPKVSFNMSIGTQSasnhsany 338
Cdd:COG1629 76 VDGVPLNdpsggdGGLSYIDPEDIERVEVLRGPSSA-LYGSGALGGVINIVTKKPKDG-KGGEVSASYGSYG-------- 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 339 mnaeeytrrladyayqqdlrawyktnptsdvgrpaypdlssreanayylrsqeekdsylsgaaydidwidkvmqtglTQD 418
Cdd:COG1629 146 -----------------------------------------------------------------------------TYR 148
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 419 YNIGVSGSSDYVNYYLSGAYHDEEGLLLNDQFKRYTFNAKVDTKVTDWLKIGANINFSHRDYsgvsanfdyatkasplaa 498
Cdd:COG1629 149 ASLSLSGGNGKLAYRLSASYRDSDGYRDNSDSDRYNLRAKLGYQLGDDTRLTLSASYSDSDQ------------------ 210
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 499 ydfDTPGYHRLELATESSMKDPLQYLAIDNSDLRNTLFLTLNGRIDvPFIKGLSYDFNYsttrYHRDNNSFYPSDVDGGF 578
Cdd:COG1629 211 ---DSPGYLTLAALRPRGAMDDGTNPYSNDTDDNTRDRYSLSLEYE-HLGDGLKLSASA----YYRYDDTDLDSDFTPTP 282
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 579 INNGKAIKEPENENAYLFNHIFAYQRTFGD-HSLNATFVYTKEkrwgdkttaiaesfDTDNLGYN-NLGIGTLFTEKSTA 656
Cdd:COG1629 283 ADGGTLEQTDFDNRTYGLELRLTYDLGFGGkHTLLVGLDYQRQ--------------DLDGSGYPlDLGSGSLPTLTSGA 348
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 657 W---QESNVGLMGRISYNYKNRYLFTGTVRRDGFSGF------------GSNNKFVTLPSASIGWVISEEdfnpfedvyL 721
Cdd:COG1629 349 DddgTTTSLALYAQDTYKLTDKLTLTAGLRYDYVSYDvddtvtgtdsasGSRSYSAFSPSLGLTYQLSPN---------L 419
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 722 KLRLSYGQngnqgigryaslaklGMGAYNYDDDRVISLYPSEMANKDLKWERTSSWNFGIDFGFFNQRLNGSFEVYKSHT 801
Cdd:COG1629 420 SLYASYSR---------------GFRAPTFGELYANGTDPYSVGNPDLKPETSTNYELGLRYRLLDGRLSLSLALFYSDV 484
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 802 TDVLVKRTLPNVTGYSWVWANLGGVDNKGVEVELNSVNIQNknfsWTSGFTFSLNRDKITDLYgdGTTQDLTNGWFVGE- 880
Cdd:COG1629 485 DNEILSVPLPNDSGFSTYYTNAGKARSYGVELELSYQLTPG----LSLNASYSYTDAKFDDDT--DGSADLDGNRLPGVp 558
|
730 740 750 760
....*....|....*....|....*....|....*....|....*...
gi 2486183734 881 --SIGAIYSYEMQGVWqeedlYSGkiYEGWYPGQQKFADLNGDGKIDA 926
Cdd:COG1629 559 plTANLGLTYEFPGGW-----SLG--LGVRYVGDRYLDDANTQGAPGG 599
|
|
| CarbopepD_reg_2 |
pfam13715 |
CarboxypepD_reg-like domain; This domain family is found in bacteria, archaea and eukaryotes, ... |
112-191 |
3.67e-18 |
|
CarboxypepD_reg-like domain; This domain family is found in bacteria, archaea and eukaryotes, and is approximately 90 amino acids in length. The family is found in association with pfam07715 and pfam00593.
Pssm-ID: 433425 [Multi-domain] Cd Length: 88 Bit Score: 80.33 E-value: 3.67e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 112 ITGVVLDAFG--PVVGANIVEKGTMNGVISDSEGRFVLNVAPG--ATLIVSYIGYVSQEIKINDQASYT----ITLREDT 183
Cdd:pfam13715 1 ISGTVVDENTgePLPGATVYVKGTTKGTVTDADGNFELKNLPAgtYTLVVSFVGYKTQEKKVTVSNDNTldvnFLLKEDA 80
|
....*...
gi 2486183734 184 ETLEEVVV 191
Cdd:pfam13715 81 LLLDEVVV 88
|
|
| ligand_gated_channel |
cd01347 |
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ... |
225-874 |
2.76e-09 |
|
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.
Pssm-ID: 238657 [Multi-domain] Cd Length: 635 Bit Score: 61.31 E-value: 2.76e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 225 ALVGSTAGVNTaQSGYAGEDVSLSIRGttsFSASQNpLIVLDGIIYNGA-------MSDINVNDISSIDILKDASAAaVY 297
Cdd:cd01347 20 DLLRRIPGVSV-TRGGGGGGSTISIRG---FGPDRT-LVLVDGLPLASSnygrgvdLNTIPPELIERVEVLKGPSSA-LY 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 298 GARSANGVILITTKKGKTEkpkvsFNMSIGTQSASNHSANYMNAeeytrrladyayqqdlrawyktnpTSDVGRPAypdl 377
Cdd:cd01347 94 GSGAIGGVVNIITKRPTDE-----FGGSVTAGYGSDNSGSSGGG------------------------GFDVSGAL---- 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 378 ssreanayylrSQEEKDSYLSGAAYDidwidkvmQTGLTQDYNIGVSGSSdyvnyylsgayhdeeglllndqFKRYTFNA 457
Cdd:cd01347 141 -----------ADDGAFGARLYGAYR--------DGDGTIDGDGQADDSD----------------------EERYNVAG 179
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 458 KVDTKVTDWLKIGANINFSHRDYsgvsaNFDYATKASPLAAYDFDTPGYHRLELATESSmkdplqylAIDNSDLRNTLFL 537
Cdd:cd01347 180 KLDWRPDDDTRLTLDAGYQDQDA-----DGPGGTLPANGTGSSLGGGPSSNTNGDRDWD--------YRDRYRKRASLGL 246
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 538 TLNGRIDVPfikGLSYDFNYSTTRYHRDNNSFYPSDVDGGFINNGKAIKEPENENAYLFNHifAYQRTFGDHSLNATFVY 617
Cdd:cd01347 247 EHDLNDTGW---TLRANLSYSYTDNDGDPLILNGGNNAAGGDLGRSGYSSERDTTQLGFDA--GLNAPFGTGPVAHTLTL 321
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 618 tkekrwGdkTTAIAESFDTDNLGynnlgigtLFTEkstAWQESNVGLMGRISYNYKNRYLFTGTVRRDGFSGFGSNNKFv 697
Cdd:cd01347 322 ------G--VEYRREELDEKQTA--------LYAQ---DTIELTDDLTLTLGLRYDHYDQDSKDTIAGGTTAKKSYSHW- 381
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 698 tLPSASIGWviseeDFNPfedvYLKLRLSYGQngnqGIGRyASLAKLGMGAYNYDDDRVislypsemANKDLKWERTSSW 777
Cdd:cd01347 382 -SPSLGLVY-----KLTD----GLSLYASYSQ----GFRA-PSLGELYGGGSHGGTAAV--------GNPNLKPEKSKQY 438
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 778 NFGIDFgFFNQRLNGSFEVYKSHTTDVLVKRTLPNVTGYSWVWANLGGVDNKGVEVELnSVNIqNKNFSWTSGFTFslNR 857
Cdd:cd01347 439 ELGLKY-DPGDGLTLSAALFRIDIKNEIVSTPTNTGLGLVTVYVNGGKARIRGVELEA-SYDL-TDGLGLTGSYTY--TD 513
|
650
....*....|....*..
gi 2486183734 858 DKITDLYGDGTTQDLTN 874
Cdd:cd01347 514 TEVKRTDGATTGNRLPG 530
|
|
| btuB |
PRK10641 |
TonB-dependent vitamin B12 receptor BtuB; |
232-338 |
3.15e-05 |
|
TonB-dependent vitamin B12 receptor BtuB;
Pssm-ID: 236730 [Multi-domain] Cd Length: 614 Bit Score: 48.06 E-value: 3.15e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 232 GVNTAQSGYAGEDVSLSIRGTtsfsASQNPLIVLDGIIYNGA-------MSDINVNDISSIDILKDASaAAVYGARSANG 304
Cdd:PRK10641 71 GVDIAQNGGLGQLSSLFIRGT----NSSHVLVLIDGVRLNQAgisgsadLSQIPISLVQRIEYIRGPR-SAVYGSDAIGG 145
|
90 100 110
....*....|....*....|....*....|....
gi 2486183734 305 VILITTkkgKTEKPKVSFNMSIGtqsaSNHSANY 338
Cdd:PRK10641 146 VVNIIT---TRDKPGTTLSAGWG----SNGYQNY 172
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| OMP_RagA_SusC |
TIGR04056 |
TonB-linked outer membrane protein, SusC/RagA family; This model describes a distinctive clade ... |
110-1089 |
0e+00 |
|
TonB-linked outer membrane protein, SusC/RagA family; This model describes a distinctive clade among the TonB-linked outer membrane proteins (OMP). Members of this family are restricted to the Bacteriodetes lineage (except for Gemmatimonas aurantiaca T-27 from the novel phylum Gemmatimonadetes) and occur in high copy numbers, with over 100 members from Bacteroides thetaiotaomicron VPI-5482 alone. Published descriptions of members of this family are available for RagA from Porphyromonas gingivalis, SusC from Bacteroides thetaiotaomicron, and OmpW from Bacteroides caccae. Members form pairs with members of the SusD/RagB family (pfam07980). Transporter complexes including these outer membrane proteins are likely to import large degradation products of proteins (e.g. RagA) or carbohydrates (e.g. SusC) as nutrients, rather than siderophores. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 274948 [Multi-domain] Cd Length: 981 Bit Score: 801.81 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 110 KKITGVVLDAFG-PVVGANIVEKGTMNGVISDSEGRFVLNVAPGATLIVSYIGYVSQEIKINDQASYTITLREDTETLEE 188
Cdd:TIGR04056 1 ITVTGVVVDETGePLIGASVVVKGTTNGTITDIDGNFSLKVPPGAVLVFSYIGYKTQEVKVKGQKNLNITLKEDTQELDE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 189 VVVVGYGTMKKKDLTGAVKRVNLEESPAVANTSLSQALVGSTAGVNTAQ-SGYAGEDVSLSIRGTTSFSASQNPLIVLDG 267
Cdd:TIGR04056 81 VVVVGYGTQKKKSLTGAVSTVKAKELKKVPVSNLSNALQGKVAGVIITQsSGEPGGDAEIWIRGISSFGGNNSPLYVIDG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 268 IIYNGAMSDINVNDISSIDILKDASAAAVYGARSANGVILITTKKGKTEKPKVSFNMSIGTQSASNHSaNYMNAEEYtrr 347
Cdd:TIGR04056 161 VPRDNGLSDLNPEDIESISVLKDASATAIYGSRGANGVILITTKRGKEGKPKISYNAEFGFSTPTRLP-EMLNAYEY--- 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 348 lADYAYQQdlrawyktnptsdvgrpaypdLSSREANAYYLRSQEEKDSYLSGAAYD----IDWIDKVM-QTGLTQDYNIG 422
Cdd:TIGR04056 237 -AELYNEA---------------------LLNRGSSPPDIYTDEEIEAYRNGLDPDlypnTDWQDEIFkRTAFNQRHNLS 294
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 423 VSGSSDYVNYYLSGAYHDEEGLLLNDQFKRYTFNAKVDTKVTDWLKIGANINFSHRDYSGVSANFD-------YATKASP 495
Cdd:TIGR04056 295 VSGGTEKARYYVSLGYYNEEGILKNSDYKRYNFRANIDAKLTKTLKLSLNVSGSLSKYNNPGGSTSniwgalmLFPRGTP 374
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 496 LAAYDFDTPGYHRLELATESSMKDPLQYLAIDNSDLRNTLFLTlNGRIDVPFIKGLSYDFNYSTTRYHRDNNSFYPSD-- 573
Cdd:TIGR04056 375 YSTPPVYSDGYYPAYNSGNTSLQNPYALLNRGYNENERNRLNG-NASLEQKITKGLKLKGTFSYDYSNYKNKKYYKNPyy 453
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 574 -VDGGFINNGKAIKEPENENAYLFNHIFAYQRTFGDHSLNATFVYTKEKRWGDKTTAIAESFDTDNLGynnlgiGTLFTE 652
Cdd:TIGR04056 454 yNATGGANNGYYSESNSRSRNYYLEATLNYNRTFGKHNVSALLGYSQQENKSSSYGGLLDDLPSLDAG------TSDASV 527
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 653 KSTAWQESNVGLMGRISYNYKNRYLFTGTVRRDGFSGFGSNNKFVTLPSASIGWVISEEDFnpFEDV-----YLKLRLSY 727
Cdd:TIGR04056 528 SGSDSEYRLQSLFGRATYSYKDRYLLEFNFRYDGSSRFAKGNRWGFFPSVSLGWRISEEKF--MKKLkkwlsFLKLRASY 605
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 728 GQNGNQGIG-RYASLAKLGMGAYNY-----DDDRVISLYPSEMANKDLKWERTSSWNFGIDFGFFNQRLNGSFEVYKSHT 801
Cdd:TIGR04056 606 GIVGNDNIGdRYPYLSLYNLGDGGYnfgtnNGTSVTGITESRYGNPNLKWEKTKKWNLGLDLGFFNNRLSLTVDYYYKKT 685
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 802 TDVLVKRTLPNVTGYSWVWANLGGVDNKGVEVELNSVNIQNKNFSWTSGFTFSLNRDKITDLygDGTTQDLTNGWF---V 878
Cdd:TIGR04056 686 KDILQSRSLPSVTGYSSPYANIGKVKNKGVELSLNYRNKIGKDFSWSVRGNFTYNKNKILEL--DEGAYLPVKYPYiskE 763
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 879 GESIGAIYSYEMQGVWQEEDlySGKIYEGWY-PGQQKFADLNGDGKIDaEHDRKIIGNKN-PNCRFSFSNTLTWKNWSLY 956
Cdd:TIGR04056 764 GGPIGQIYGYIADGLFKDDD--SPKQTFGNVrPGDIKYKDVNGDGKID-DDDRVPIGYSNtPDLTYGFGNSFSYKGFDLS 840
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 957 FMLNSMLGGGGYYMGGNGLLAPDNSSDYVVrlnQPAIREYWTPENHSNEGLALFRNQPISTSIYQ-------NRGFVRLQ 1029
Cdd:TIGR04056 841 ALFQGSGGGDVFNDGRGFYPFNGGDWGNVL---KIVADNRWTPENPNADYPRLSYGDSNNSNNYQastrwleDGSYLRLK 917
|
970 980 990 1000 1010 1020
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2486183734 1030 DVSLMYSFDKKLLQKTGvISQLQLFLTGKNLYTFTGWDGWDPE-----YTAFPLTRSLQFGIKLS 1089
Cdd:TIGR04056 918 NLTLGYTLPKKWLKKIG-ISNLRVYFSGQNLFTFSKYKGWDPElqgndGGAYPLQRTFSFGVNLT 981
|
|
| CirA |
COG1629 |
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism]; |
186-926 |
2.91e-52 |
|
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];
Pssm-ID: 441236 [Multi-domain] Cd Length: 644 Bit Score: 195.05 E-value: 2.91e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 186 LEEVVVVGYGT-MKKKDLTGAVKRVNLEESPAVANTSLSQALvGSTAGVNTAQSGyaGEDVSLSIRGTTSfsASQNPLIV 264
Cdd:COG1629 1 LEEVVVTATRTdESLQDVPGSVSVISREQLEDQPATDLGDLL-RRVPGVSVTSAG--GGAGQISIRGFGG--GGNRVLVL 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 265 LDGIIYN------GAMSDINVNDISSIDILKDASAAaVYGARSANGVILITTKKGKTEkPKVSFNMSIGTQSasnhsany 338
Cdd:COG1629 76 VDGVPLNdpsggdGGLSYIDPEDIERVEVLRGPSSA-LYGSGALGGVINIVTKKPKDG-KGGEVSASYGSYG-------- 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 339 mnaeeytrrladyayqqdlrawyktnptsdvgrpaypdlssreanayylrsqeekdsylsgaaydidwidkvmqtglTQD 418
Cdd:COG1629 146 -----------------------------------------------------------------------------TYR 148
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 419 YNIGVSGSSDYVNYYLSGAYHDEEGLLLNDQFKRYTFNAKVDTKVTDWLKIGANINFSHRDYsgvsanfdyatkasplaa 498
Cdd:COG1629 149 ASLSLSGGNGKLAYRLSASYRDSDGYRDNSDSDRYNLRAKLGYQLGDDTRLTLSASYSDSDQ------------------ 210
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 499 ydfDTPGYHRLELATESSMKDPLQYLAIDNSDLRNTLFLTLNGRIDvPFIKGLSYDFNYsttrYHRDNNSFYPSDVDGGF 578
Cdd:COG1629 211 ---DSPGYLTLAALRPRGAMDDGTNPYSNDTDDNTRDRYSLSLEYE-HLGDGLKLSASA----YYRYDDTDLDSDFTPTP 282
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 579 INNGKAIKEPENENAYLFNHIFAYQRTFGD-HSLNATFVYTKEkrwgdkttaiaesfDTDNLGYN-NLGIGTLFTEKSTA 656
Cdd:COG1629 283 ADGGTLEQTDFDNRTYGLELRLTYDLGFGGkHTLLVGLDYQRQ--------------DLDGSGYPlDLGSGSLPTLTSGA 348
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 657 W---QESNVGLMGRISYNYKNRYLFTGTVRRDGFSGF------------GSNNKFVTLPSASIGWVISEEdfnpfedvyL 721
Cdd:COG1629 349 DddgTTTSLALYAQDTYKLTDKLTLTAGLRYDYVSYDvddtvtgtdsasGSRSYSAFSPSLGLTYQLSPN---------L 419
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 722 KLRLSYGQngnqgigryaslaklGMGAYNYDDDRVISLYPSEMANKDLKWERTSSWNFGIDFGFFNQRLNGSFEVYKSHT 801
Cdd:COG1629 420 SLYASYSR---------------GFRAPTFGELYANGTDPYSVGNPDLKPETSTNYELGLRYRLLDGRLSLSLALFYSDV 484
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 802 TDVLVKRTLPNVTGYSWVWANLGGVDNKGVEVELNSVNIQNknfsWTSGFTFSLNRDKITDLYgdGTTQDLTNGWFVGE- 880
Cdd:COG1629 485 DNEILSVPLPNDSGFSTYYTNAGKARSYGVELELSYQLTPG----LSLNASYSYTDAKFDDDT--DGSADLDGNRLPGVp 558
|
730 740 750 760
....*....|....*....|....*....|....*....|....*...
gi 2486183734 881 --SIGAIYSYEMQGVWqeedlYSGkiYEGWYPGQQKFADLNGDGKIDA 926
Cdd:COG1629 559 plTANLGLTYEFPGGW-----SLG--LGVRYVGDRYLDDANTQGAPGG 599
|
|
| FepA |
COG4771 |
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and ... |
173-854 |
4.08e-39 |
|
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism];
Pssm-ID: 443803 [Multi-domain] Cd Length: 612 Bit Score: 155.01 E-value: 4.08e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 173 ASYTITLREDTETLEEVVVVGYGT-MKKKDLTGAVKRVNLEESPAVANTSLSQALvGSTAGVNTAQSGYAGEDVSLSIRG 251
Cdd:COG4771 14 AQAADALAEDATELEEVVVTATRTeQSLSDAPASVSVITAEEIEKLGATDLADAL-RLLPGVSVTRSGGRGGSSGISIRG 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 252 ttsfSASQNPLIVLDGI-IYN------GAMSDINVNDISSIDILKDAsAAAVYGARSANGVILITTKKGKTEKpkvSFNM 324
Cdd:COG4771 93 ----LGGDRVLVLIDGVpVNNpalgggGDLSYIPPDDIERIEVIRGP-ASALYGSDAIGGVINIITKKPTDEL---EGSV 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 325 SIGTQSASNHsanymnaeeytrrladyayqqdlrawyktnptsdvgrpaypdlssreanayylrsqeekdsylsgaaydi 404
Cdd:COG4771 165 SLGYGSNGNG---------------------------------------------------------------------- 174
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 405 dwidkvmqtglTQDYNIGVSGSSDYVNYYLSGAYHDEEG--------LLLNDQFKRYTFNAKVDTKVTDWLKIGANINFS 476
Cdd:COG4771 175 -----------TYSGSLSLGGPGDKLSFLLSGSYRDRDGyldyrnggFVGNSGYERYNLNAKLGYRLSDNHRLSLSGGYS 243
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 477 HRDYSGVSANFDYATKASPLAAYDfdtpgyhrlelatessmkdplqylaiDNSDLRNTLFLTLNGRIDvpfiKGLSYDFN 556
Cdd:COG4771 244 RQDRDGGPPTLGDTEISSDNAGDR--------------------------DTTTDRGNYSLRYNGDLG----DNLDLSLY 293
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 557 YSTTRYHRDNNSFYPSDVDGgfinngkaikEPENENAYLFNHIFAYqRTFGDHSLNATFVYTKEKrwgdkttaiaesFDT 636
Cdd:COG4771 294 YSRTDRDSTNGSLGGSTGSF----------SDSDDTTYGLELDLTY-PLGGNHTLTLGAEYRYDD------------LDS 350
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 637 DNLGYNnlgigtlfteksTAWQESNVGLMGRISYNYKNRYLFTGTVRRDGFSGFGSNNKFVTLPSASIGWVISEEdfnpf 716
Cdd:COG4771 351 SSFLGG------------ADASRDTYGLFAQDEWKLTDKLTLTAGLRYDYYSTFGASNYTAFSPRLGLRYDLSDN----- 413
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 717 edvyLKLRLSYGQNGnqgigRYASLAKLGMGAYNYDDDRVIslypsemANKDLKWERTSSWNFGIDFGFFNQRLNGSFEV 796
Cdd:COG4771 414 ----LTLRASYGRGF-----RAPSLAELYGSGTGTPGRYVL-------GNPDLKPETSDNYELGLEYRLGNGGLSLSLTG 477
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....*...
gi 2486183734 797 YKSHTTDVLVKRTLPNVTGYSWVWANLGGVDNKGVEVELNsVNIqNKNFSWTSGFTFS 854
Cdd:COG4771 478 FYTDIKDLIVLVPVGPGPGDVLQYENVGKARTYGLELELK-YRL-GKGLTLTASYTYL 533
|
|
| BtuB |
COG4206 |
Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism]; |
189-489 |
2.66e-32 |
|
Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism];
Pssm-ID: 443355 [Multi-domain] Cd Length: 276 Bit Score: 127.30 E-value: 2.66e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 189 VVVVGYG-TMKKKDLTGAVKRVNLEESPAVANTSLSQALvGSTAGVNTAQSGYAGEDVSLSIRGTTSfsasQNPLIVLDG 267
Cdd:COG4206 1 VVVTATRlEQSKSDLTGSVTVIDAEELERSGATSLADAL-RRVPGVQVSSSGGPGSAASISIRGLGS----NQTLVLIDG 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 268 IIYNGAM------SDINVNDISSIDILKDAsAAAVYGARSANGVILITTKKGKtEKPKVSFNMSIGTQSASNHSANYMNA 341
Cdd:COG4206 76 VPLNDPSlggvdlSLIPPDDIERIEVLKGA-ASALYGSDAIGGVINITTKKGK-KGFKGSVSASYGSFGTRRLSASLSGG 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 342 EEYTRRLADYAYQQdlrawyktnpTSDVGrpaYPDLSSREANAYylrsqeEKDSYLSGAAYDidwidkvmqtgLTQDYNI 421
Cdd:COG4206 154 AGKFSYSLSASYRR----------SDGYR---YNDPDLRNNDGY------ENTSLNARLGYK-----------LGDNGSL 203
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2486183734 422 GVSG--SSDYVNYYLSGAYHDEEGLLLNDQFKR---YTFNAKVDTKVTDWLKIGANINFSHRDYSGVSANFDY 489
Cdd:COG4206 204 SLSGgySDSERGYPGAVGSDRNLRLSLSLEYKLsdgWSLLLLAYYYYDRDYEDGGGDSAGTSNTDGARAGLSY 276
|
|
| CarbopepD_reg_2 |
pfam13715 |
CarboxypepD_reg-like domain; This domain family is found in bacteria, archaea and eukaryotes, ... |
112-191 |
3.67e-18 |
|
CarboxypepD_reg-like domain; This domain family is found in bacteria, archaea and eukaryotes, and is approximately 90 amino acids in length. The family is found in association with pfam07715 and pfam00593.
Pssm-ID: 433425 [Multi-domain] Cd Length: 88 Bit Score: 80.33 E-value: 3.67e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 112 ITGVVLDAFG--PVVGANIVEKGTMNGVISDSEGRFVLNVAPG--ATLIVSYIGYVSQEIKINDQASYT----ITLREDT 183
Cdd:pfam13715 1 ISGTVVDENTgePLPGATVYVKGTTKGTVTDADGNFELKNLPAgtYTLVVSFVGYKTQEKKVTVSNDNTldvnFLLKEDA 80
|
....*...
gi 2486183734 184 ETLEEVVV 191
Cdd:pfam13715 81 LLLDEVVV 88
|
|
| Plug |
pfam07715 |
TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently ... |
198-305 |
1.14e-14 |
|
TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently folding subunit of the TonB-dependent receptors. It acts as the channel gate, blocking the pore until the channel is bound by ligand. At this point it under goes conformational changes opens the channel.
Pssm-ID: 462243 [Multi-domain] Cd Length: 107 Bit Score: 70.76 E-value: 1.14e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 198 KKKDLTGAVKRVNLEESPAVANTSLSQALvGSTAGVNtAQSGYAGEDVSLSIRGTTSfsasQNPLIVLDGI------IYN 271
Cdd:pfam07715 1 DLRDTPGSVSVVTAEDIEDQGATNLADAL-RGVPGVS-VSSGGGGGGSSISIRGFGS----NRVLVLVDGVplnsggGGS 74
|
90 100 110
....*....|....*....|....*....|....
gi 2486183734 272 GAMSDINVNDISSIDILKDAsAAAVYGARSANGV 305
Cdd:pfam07715 75 VDLNSIDPEDIERVEVLKGP-ASALYGSGAIGGV 107
|
|
| TonB_dep_Rec |
pfam00593 |
TonB dependent receptor; This model now only covers the conserved part of the barrel structure. |
527-836 |
5.71e-13 |
|
TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
Pssm-ID: 395474 [Multi-domain] Cd Length: 475 Bit Score: 72.50 E-value: 5.71e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 527 DNSDLRNTLFLTLNGRIDVPFIKGLSYDFNYSTTRYHRDNNSFYPSDvDGGFINNGKAIKEPENENAYLFNHIFAYQRTF 606
Cdd:pfam00593 57 DTDRKRLSLGYDYDLGDGLSWLSTLRLGLRYSSLDGDYTSNSSGLSG-AGDYLSDDRLYGLYGLDGDLELSLDLSHDLLL 135
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 607 GDHSLNATFVYTkekrwgdkttaiaesfDTDNLGYNNLGIGTLFTEKSTAWQESNVGLMGRISYNYKNRYLFTGTVRRDG 686
Cdd:pfam00593 136 GVELRTAGLDYR----------------RLDDDAYDPYDPANPSSSSYSDTTTDSYGLYLQDNIKLTDRLTLTLGLRYDH 199
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 687 FSGFGSN----------NKFVTLPSASIGWVISEEdfnpfedvyLKLRLSYGQngnqgIGRYASLAKLGMGAYNYDDDRV 756
Cdd:pfam00593 200 YSTDGDDgngggdnfsrSYSAFSPRLGLVYKPTDN---------LSLYASYSR-----GFRAPSLGELYGSGSGGGGGAV 265
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 757 ISlypsemANKDLKWERTSSWNFGIDfgFFNQRLNGSFEVYKSHTTDVLVKRTLPNV-TGYSWVWANLGGVDNKGVEVEL 835
Cdd:pfam00593 266 AG------GNPDLKPETSDNYELGLK--YDDGRLSLSLALFYIDIKNLITSDPDGPGlGGTVYTYTNVGKARIRGVELEL 337
|
.
gi 2486183734 836 N 836
Cdd:pfam00593 338 S 338
|
|
| SusC_RagA_signa |
TIGR04057 |
TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; This model ... |
281-311 |
1.39e-12 |
|
TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; This model describes a 31-residue signature region of the SusC/RagA family of outer membrane proteins from the Bacteriodetes. While many TonB-dependent outer membrane receptors are associated with siderophore import, this family seems to include generalized nutrient receptors that may convey fairly large oligomers of protein or carbohydrate. This family occurs in high copy numbers in the most abundant species of the human gut microbiome.
Pssm-ID: 274949 [Multi-domain] Cd Length: 31 Bit Score: 62.60 E-value: 1.39e-12
10 20 30
....*....|....*....|....*....|.
gi 2486183734 281 DISSIDILKDASAAAVYGARSANGVILITTK 311
Cdd:TIGR04057 1 DIESISVLKDASAAAIYGSRGANGVILITTK 31
|
|
| Fiu |
COG4774 |
Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism]; |
220-853 |
9.85e-11 |
|
Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism];
Pssm-ID: 443806 [Multi-domain] Cd Length: 639 Bit Score: 65.67 E-value: 9.85e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 220 TSLSQALvGSTAGVnTAQSGYAGEDVSLSIRGttsFSASQNplIVLDGIiYNGAMSDINVNDISSIDILKdASAAAVYGA 299
Cdd:COG4774 27 TSLADAL-RNVPGV-TFGAGEGGNGDSFSIRG---FSASGD--IYVDGL-RDPGQYRRDTFNLERVEVLK-GPASVLYGR 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 300 RSANGVILITTKKGKTEkPKVSFNMSIGTQSasnhsanymnaeeyTRRLadyayqqdlrawyktnpTSDVGRPAYPDLSs 379
Cdd:COG4774 98 GSPGGVINLVTKRPTDE-PFTEVTLTYGSDG--------------QRRA-----------------TLDVNGPLGDDLA- 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 380 reanayylrsqeekdsylsgaaydidwidkvmqtgltqdynigvsgssdyvnYYLSGAYHDEEGLLLNDQFKRYTFNAKV 459
Cdd:COG4774 145 ----------------------------------------------------YRLNGMYRDSDSYRDGVDNDRWGIAPSL 172
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 460 DTKVTDWLKIGANINFSHRDYSgvsanfdyatkasplaaYDFDTPGYHRLELATEssmkDPLQYLAIDNSDLR-NTLFLT 538
Cdd:COG4774 173 TWRLGDRTRLTLDYEYQDDDRT-----------------PDYGVPAVANGRPVDV----DRSTFYGQPDDYSDsETDSAT 231
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 539 LNgridvpfikgLSYDFN-----YSTTRY---HRDNNSFYPSDVD-GGFINNGKAIKEPENENAYLFNHIFAYQRTFG-D 608
Cdd:COG4774 232 LR----------LEHDFNdnwtlRNALRYsdyDRDYRNTYPTGGNaTGTVTRSAYRRDQDNDTLSNQTDLTGKFDTGGvK 301
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 609 HSLNATFVYTKEKRWGDKTTAIAESFDTD--NLGYNNLGIGTLFTEKSTAWQESNVG--LMGRISYNykNRYLFTGTVRR 684
Cdd:COG4774 302 HTLLAGVEYSREDSDNARYSGGGTAPTVNlyNPVYGAPVTGPTLGGADNDSRTDTTGlyLQDTISLT--DRWSLLAGLRY 379
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 685 D-----------GFSGFGSNNKFVTlPSASIGWVISeEDFNPFedvylklrLSYGQNGNQGIGRYASLAklgmgaynydd 753
Cdd:COG4774 380 DrfdtdytdrttGATTSSYDDSAFS-PRAGLVYKPT-PNLSLY--------ASYSTSFNPGGGAPSLSN----------- 438
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 754 drvislypsemANKDLKWERTSSWNFGIDFGFFNQRLNGSFEVYKSHTTDVLVkrTLPNVTGYSwvwANLGGVDNKGVEV 833
Cdd:COG4774 439 -----------AGQALDPEKSRQYEVGVKWDLLDGRLSLTAALFRIEKTNVRT--TDPANPGVY---VQTGEQRSRGVEL 502
|
650 660
....*....|....*....|
gi 2486183734 834 ELnSVNIqNKNFSWTSGFTF 853
Cdd:COG4774 503 EA-TGEL-TPGWSVLAGYTY 520
|
|
| FecA |
COG4772 |
Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism]; |
181-338 |
6.42e-10 |
|
Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];
Pssm-ID: 443804 [Multi-domain] Cd Length: 681 Bit Score: 63.41 E-value: 6.42e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 181 EDTETLEEVVVVGYGTMKK--KDLTGAVKRVNLEESPAVANTSLSQALvGSTAGVNTAQSGYAGEDVSLSIRGTTSfSAS 258
Cdd:COG4772 18 EAATTLETVVVTGSRAAEArlKDVPGSVSVVDREELENQAATSLREVL-RRVPGVNVQEEDGFGLRPNIGIRGLGP-RRS 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 259 QNPLIVLDGI-------IYNGAMSDINVNDISSIDILKDASAAAvYGARSANGVILITTKKGkTEKPKVSFNMSIGTQSA 331
Cdd:COG4772 96 RGITLLEDGIpiapapyGDPAAYYFPDLERMERIEVLRGAAALR-YGPQTVGGAINFVTRTI-PTAFGGELRVTGGSFGY 173
|
....*..
gi 2486183734 332 SNHSANY 338
Cdd:COG4772 174 RRTHASV 180
|
|
| FhuE |
COG4773 |
Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion ... |
153-884 |
1.31e-09 |
|
Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion transport and metabolism];
Pssm-ID: 443805 [Multi-domain] Cd Length: 692 Bit Score: 62.22 E-value: 1.31e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 153 ATLIVSYIGYVSQEIkindQASYTITLREDTETLEEVVVVG----YGTMKKKDLTGAVK-RVNLEESPAVAN-------- 219
Cdd:COG4773 3 ALLAGSGLAAAAAGA----LAQAAAAAAAEATTLPEVTVTGtaegTGGYTAKSSSTATKlDTPLRETPQSVSvvtrqlie 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 220 ----TSLSQALvGSTAGVNTAQSGYAGEDvSLSIRGttsFSASQnplIVLDGI-IYNGAMSDINVNDISSIDILKDASAA 294
Cdd:COG4773 79 dqgaTTLDDAL-RNVPGVTVSSYDGGGRD-SFSIRG---FSIDN---YLRDGLpLGGFGGGQPDTANLERVEVLKGPAGL 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 295 aVYGARSANGVILITTKKGkTEKPKVSFNMSIGTQSasnhsanymnaeeyTRRLadyayqqdlrawyktnpTSDVGRPay 374
Cdd:COG4773 151 -LYGAGSPGGLVNLVTKRP-TAEPQGEVSLSAGSWD--------------TYRA-----------------TADVGGP-- 195
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 375 pdlssreanayylrsqeekdsylsgaaydidwidkvmqtgLTQDYNIGvsgssdyvnYYLSGAYHDEEGLLLNDQFKRYT 454
Cdd:COG4773 196 ----------------------------------------LNEDGTLR---------YRLNAAYEDGDSFRDGVDNRRTL 226
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 455 FNAKVDTKVTDWLKIGANINFSHRDYSGVSANFdyatkasPLAAYDFDTPgyhrlelaTESSMKDPLQYLAIDNsdlrNT 534
Cdd:COG4773 227 IAPSLDWDLTDDTTLTLGAEYQDDDSTGDRGFL-------PLDGTLLDLP--------RSTNLGEPWDYYDTET----TT 287
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 535 LFLTLNGRIDvpfiKGLSYDFNYSTTRYHRDNNSFYPS---DVDGGFINNGKAIKEPENENAYLFNHIFAYQRTFG-DHS 610
Cdd:COG4773 288 LFAELEHRFN----DDWSLRANARYSDSDRDGRSAYAYgapDAATGTLTRYASARDGDSRSDSLDANLNGKFETGGlEHT 363
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 611 LNATFVYTKEKRwgDKTTAIAESFDTDNLGYNNL-GIGTLFTEKSTAWQESNVGLMGRISYNykNRYLFTGTVRRDGFSG 689
Cdd:COG4773 364 LLVGADYSRYDS--DSDSATAGTINIYNPVYGNLpEPDFDASDTDTTTRQTGLYAQDQISLT--DRLSLLLGGRYDWYET 439
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 690 FGSNNKF---------VTLPSASIGWVISeEDFNPFedvylklrLSYGQNGNQGIGRYASlaklgmgaynydddrvisly 760
Cdd:COG4773 440 DSTNRLGgsttsyddsAFTPRAGLVYDLT-PGLSLY--------ASYSESFEPQSGADNN-------------------- 490
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 761 psemaNKDLKWERTSSWNFGIDFGFFNQRLNGSFEVYKSHTTDVLVkrTLPNVTGYSwvwANLGGVDNKGVEVELnSVNI 840
Cdd:COG4773 491 -----GNPLDPETGKQYEAGVKGELFDGRLNATLAVFDITQKNVAT--TDPDNPNFY---VQVGEVRSRGVELEL-SGEL 559
|
730 740 750 760 770
....*....|....*....|....*....|....*....|....*....|....*...
gi 2486183734 841 qNKNFSWTSGFTFSLNRDKITDLYGDG--------------TTQDLTNGWFVGESIGA 884
Cdd:COG4773 560 -TPGLNLIAGYTYTDAKITKDADALEGkrltnvprhtaslwTTYRFPSGALKGLGLGG 616
|
|
| CarboxypepD_reg |
pfam13620 |
Carboxypeptidase regulatory-like domain; |
112-179 |
2.05e-09 |
|
Carboxypeptidase regulatory-like domain;
Pssm-ID: 433354 [Multi-domain] Cd Length: 81 Bit Score: 54.98 E-value: 2.05e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 112 ITGVVLDAFG-PVVGANIV----EKGTMNGVISDSEGRFVL-NVAPGA-TLIVSYIGYVSQEIK-----INDQASYTITL 179
Cdd:pfam13620 2 ISGTVTDPSGaPVPGATVTvtntDTGTVRTTTTDADGRYRFpGLPPGTyTVTVSAPGFKTATRTgvtvtAGQTTTLDVTL 81
|
|
| ligand_gated_channel |
cd01347 |
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ... |
225-874 |
2.76e-09 |
|
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.
Pssm-ID: 238657 [Multi-domain] Cd Length: 635 Bit Score: 61.31 E-value: 2.76e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 225 ALVGSTAGVNTaQSGYAGEDVSLSIRGttsFSASQNpLIVLDGIIYNGA-------MSDINVNDISSIDILKDASAAaVY 297
Cdd:cd01347 20 DLLRRIPGVSV-TRGGGGGGSTISIRG---FGPDRT-LVLVDGLPLASSnygrgvdLNTIPPELIERVEVLKGPSSA-LY 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 298 GARSANGVILITTKKGKTEkpkvsFNMSIGTQSASNHSANYMNAeeytrrladyayqqdlrawyktnpTSDVGRPAypdl 377
Cdd:cd01347 94 GSGAIGGVVNIITKRPTDE-----FGGSVTAGYGSDNSGSSGGG------------------------GFDVSGAL---- 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 378 ssreanayylrSQEEKDSYLSGAAYDidwidkvmQTGLTQDYNIGVSGSSdyvnyylsgayhdeeglllndqFKRYTFNA 457
Cdd:cd01347 141 -----------ADDGAFGARLYGAYR--------DGDGTIDGDGQADDSD----------------------EERYNVAG 179
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 458 KVDTKVTDWLKIGANINFSHRDYsgvsaNFDYATKASPLAAYDFDTPGYHRLELATESSmkdplqylAIDNSDLRNTLFL 537
Cdd:cd01347 180 KLDWRPDDDTRLTLDAGYQDQDA-----DGPGGTLPANGTGSSLGGGPSSNTNGDRDWD--------YRDRYRKRASLGL 246
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 538 TLNGRIDVPfikGLSYDFNYSTTRYHRDNNSFYPSDVDGGFINNGKAIKEPENENAYLFNHifAYQRTFGDHSLNATFVY 617
Cdd:cd01347 247 EHDLNDTGW---TLRANLSYSYTDNDGDPLILNGGNNAAGGDLGRSGYSSERDTTQLGFDA--GLNAPFGTGPVAHTLTL 321
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 618 tkekrwGdkTTAIAESFDTDNLGynnlgigtLFTEkstAWQESNVGLMGRISYNYKNRYLFTGTVRRDGFSGFGSNNKFv 697
Cdd:cd01347 322 ------G--VEYRREELDEKQTA--------LYAQ---DTIELTDDLTLTLGLRYDHYDQDSKDTIAGGTTAKKSYSHW- 381
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 698 tLPSASIGWviseeDFNPfedvYLKLRLSYGQngnqGIGRyASLAKLGMGAYNYDDDRVislypsemANKDLKWERTSSW 777
Cdd:cd01347 382 -SPSLGLVY-----KLTD----GLSLYASYSQ----GFRA-PSLGELYGGGSHGGTAAV--------GNPNLKPEKSKQY 438
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 778 NFGIDFgFFNQRLNGSFEVYKSHTTDVLVKRTLPNVTGYSWVWANLGGVDNKGVEVELnSVNIqNKNFSWTSGFTFslNR 857
Cdd:cd01347 439 ELGLKY-DPGDGLTLSAALFRIDIKNEIVSTPTNTGLGLVTVYVNGGKARIRGVELEA-SYDL-TDGLGLTGSYTY--TD 513
|
650
....*....|....*..
gi 2486183734 858 DKITDLYGDGTTQDLTN 874
Cdd:cd01347 514 TEVKRTDGATTGNRLPG 530
|
|
| btuB |
PRK10641 |
TonB-dependent vitamin B12 receptor BtuB; |
232-338 |
3.15e-05 |
|
TonB-dependent vitamin B12 receptor BtuB;
Pssm-ID: 236730 [Multi-domain] Cd Length: 614 Bit Score: 48.06 E-value: 3.15e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 232 GVNTAQSGYAGEDVSLSIRGTtsfsASQNPLIVLDGIIYNGA-------MSDINVNDISSIDILKDASaAAVYGARSANG 304
Cdd:PRK10641 71 GVDIAQNGGLGQLSSLFIRGT----NSSHVLVLIDGVRLNQAgisgsadLSQIPISLVQRIEYIRGPR-SAVYGSDAIGG 145
|
90 100 110
....*....|....*....|....*....|....
gi 2486183734 305 VILITTkkgKTEKPKVSFNMSIGtqsaSNHSANY 338
Cdd:PRK10641 146 VVNIIT---TRDKPGTTLSAGWG----SNGYQNY 172
|
|
| TonB-siderophor |
TIGR01783 |
TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of ... |
211-361 |
3.39e-04 |
|
TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of TonB-dependent outer membrane siderophore receptors. It has no overlap with TonB receptors known to transport other substances, but is likely incomplete due to lack of characterizations. It is likely that genuine siderophore receptors will be identified which score below the noise cutoff to this model at which point the model should be updated. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]
Pssm-ID: 273805 [Multi-domain] Cd Length: 651 Bit Score: 44.71 E-value: 3.39e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486183734 211 LEESPAvanTSLSQALvGSTAGVNTAQSGYAGEDVSLSIRGTTSFSASQNplIVLDGII--YNGAMSDINVNDISSIDIL 288
Cdd:TIGR01783 14 LEDQQA---GSLSEAL-QRVPGVVVGGSGGTTQFGNITIRGFGLEVDIDN--VYLDGVPllSRGNLAIVDPAMVERVEVL 87
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2486183734 289 KDAsAAAVYGARSANGVILITTKKGKTEkPKVSFNMSIGTQSASNHSANY--MNAEEYTRRLADYAYQQDLRAWY 361
Cdd:TIGR01783 88 RGP-ASLLYGGSAPGGVINIVTKRPQDE-PKGSVTFGAGTRSGYRTAFDLggPLGADGTFRGRLNGARQDGDSFY 160
|
|
| |
