|
Name |
Accession |
Description |
Interval |
E-value |
| mpl |
TIGR01081 |
UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase; Alternate name: ... |
2-466 |
0e+00 |
|
UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase; Alternate name: murein tripeptide ligase [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 130153 [Multi-domain] Cd Length: 448 Bit Score: 624.94 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486244059 2 HIHILGICGTFMGGLALIARAAGHRVTGCDMAVYPPMSTQLEEQGIELIEGYGAEQLALKPDLFIIGNVVSRGNPLMEAI 81
Cdd:TIGR01081 1 HIHILGICGTFMGGLAMIAKQLGHEVTGSDANVYPPMSTQLEAQGIEIIEGFDAAQLEPKPDLVVIGNAMKRGNPCVEAV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486244059 82 LNEGLPFTSGPQWLGEQILRQQHVLAIAGTHGKTTTSSMLAWILQYAGLAPNFLIGGIAQNFGISARFDAAQrYFVIEAD 161
Cdd:TIGR01081 81 LNLNLPYTSGPQWLHDFVLHDRWVLAVAGTHGKTTTASMLAWVLEQCGLKPGFLIGGVPGNFGVSARLGESP-FFVIEAD 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486244059 162 EYDTAFFDKRSKFVHYRPRTAVLNNLEFDHADIFENLAAIQKQFHHLVRIIPQQGRVIYPAADQALQEVLAMGCWSEQCS 241
Cdd:TIGR01081 160 EYDTAFFDKRSKFVHYRPRTLVLNNLEFDHADIFDDLKAIQRQFHHLVRTVPGEGLILCPGRDQSLKDTLAKGCWSEQEF 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486244059 242 LGSglahehdhasdpKATWNVRLIEASGSQFEVLHGAEVIATIEWSLIGLHNVQNALAAISAAEHIGVAPTLACEALSHF 321
Cdd:TIGR01081 240 FGE------------QGEWQAEKITADGSHFDVLLDGEKVGEVKWSLVGRHNMHNALMAIAAARHVGVAIEDACEALGSF 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486244059 322 EGIKRRMELRATVQNIAVYDDFAHHPTAISTTLAGLRKQVGDARIIAVLEPRSNTMKLGTMSARLPASLQQADLLFCYne 401
Cdd:TIGR01081 308 VNAKRRLELKGEANGITVYDDFAHHPTAIEATLQGLRQKVGGARILAVLEPRSNTMKLGVHKDDLAPSLGRADQVFLY-- 385
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2486244059 402 tQGKHsIHWDAERVFATMSQPTEVHHDLEQLVQAVAAAAQPGDHILVMSNGGFGGFHDKLISKLK 466
Cdd:TIGR01081 386 -QPGQ-IPWDVAEVAAQCVQPANVSADFDAFVAMIVKNAQPGDHILVMSNGGFGGIHGKLLDALR 448
|
|
| MurC |
COG0773 |
UDP-N-acetylmuramate-alanine ligase MurC and related ligases, MurC/Mpl family [Cell wall ... |
1-461 |
0e+00 |
|
UDP-N-acetylmuramate-alanine ligase MurC and related ligases, MurC/Mpl family [Cell wall/membrane/envelope biogenesis]; UDP-N-acetylmuramate-alanine ligase MurC and related ligases, MurC/Mpl family is part of the Pathway/BioSystem: Mureine biosynthesis
Pssm-ID: 440536 [Multi-domain] Cd Length: 451 Bit Score: 544.66 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486244059 1 MHIHILGICGTFMGGLALIARAAGHRVTGCDMAVYPpMSTQLEEQGIELIEGYGAEQLAlKPDLFIIGNVVSRGNPLMEA 80
Cdd:COG0773 5 MHIHFIGIGGIGMSGLAEILLALGYKVSGSDLAESP-MTERLEALGIPVFIGHDAENID-DADLVVVSSAIPRDNPELVA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486244059 81 ILNEGLPFTSGPQWLGEqILRQQHVLAIAGTHGKTTTSSMLAWILQYAGLAPNFLIGGIAQNFGISARFDAAqRYFVIEA 160
Cdd:COG0773 83 ARERGIPVLSRAEMLAE-LMRGKRSIAVAGTHGKTTTTSMLAHILEEAGLDPTFLIGGILNNFGTNARLGDG-DYFVAEA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486244059 161 DEYDTAFfdkrskfVHYRPRTAVLNNLEFDHADIFENLAAIQKQFHHLVRIIPQQGRVIYPAADQALQEVLAMgCWSEQC 240
Cdd:COG0773 161 DESDGSF-------LHYSPDIAVVTNIEADHLDIYGDLEAIKEAFHEFARNVPFYGLLVLCADDPGLRELLPR-CGRPVI 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486244059 241 SLGSglahehdhasDPKATWNVRLIEAS--GSQFEVLHGAEVIATIEWSLIGLHNVQNALAAISAAEHIGVAPTLACEAL 318
Cdd:COG0773 233 TYGF----------SEDADYRAENIRIDggGSTFDVLRRGEELGEVELNLPGRHNVLNALAAIAVALELGVDPEAIAEAL 302
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486244059 319 SHFEGIKRRMELRATVQNIAVYDDFAHHPTAISTTLAGLRKQVGDARIIAVLEPRSNTMkLGTMSARLPASLQQADLLFC 398
Cdd:COG0773 303 ASFKGVKRRFELKGEVGGVTVIDDYAHHPTEIAATLAAAREKYPDRRLVAVFQPHRYSR-TRDFLDEFAEALSLADEVIL 381
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2486244059 399 Y-------NETQGkhsihWDAERVFATM---SQPTEVHHDLEQLVQAVAAAAQPGDHILVMSNGGFGGFHDKL 461
Cdd:COG0773 382 LdiyaareKPIPG-----VSSEDLAEAIrkrGKDVVYVPDLDELVEALAEIARPGDVVLTMGAGDIGGLGEKL 449
|
|
| murC |
TIGR01082 |
UDP-N-acetylmuramate--L-alanine ligase; This model describes the MurC protein in bacterial ... |
2-462 |
2.96e-78 |
|
UDP-N-acetylmuramate--L-alanine ligase; This model describes the MurC protein in bacterial peptidoglycan (murein) biosynthesis. In a few species (Mycobacterium leprae, the Chlamydia), the amino acid may be L-serine or glycine instead of L-alanine. A related protein, UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase (murein tripeptide ligase) is described by model TIGR01081. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273433 [Multi-domain] Cd Length: 448 Bit Score: 250.69 E-value: 2.96e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486244059 2 HIHILGICGTFMGGLALIARAAGHRVTGCDMAVYPpMSTQLEEQGIELIEGYGAEQLALkPDLFIIGNVVSRGNPLMEAI 81
Cdd:TIGR01082 1 KIHFVGIGGIGMSGIAEILLNRGYQVSGSDIAENA-TTKRLEALGIPIYIGHSAENLDD-ADVVVVSAAIKDDNPEIVEA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486244059 82 LNEGLPFTSGPQWLGEqILRQQHVLAIAGTHGKTTTSSMLAWILQYAGLAPNFLIGGIAQNFGISARFdAAQRYFVIEAD 161
Cdd:TIGR01082 79 KERGIPVIRRAEMLAE-LMRFRHSIAVAGTHGKTTTTAMIAVILKEAGLDPTVVVGGLVKEAGTNARL-GSGEYLVAEAD 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486244059 162 EYDtaffdkrSKFVHYRPRTAVLNNLEFDHADIFENLAAIQKQ-FHHLVRIIPQQGRVIYPAADQALQEVLAMGcwSEQC 240
Cdd:TIGR01082 157 ESD-------ASFLHLQPNVAIVTNIEPDHLDTYGSSFERLKAaFEKFIHNLPFYGLAVICADDPVLRELVPKA--TEQV 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486244059 241 SLGSGlahehdhaSDPKATWNVRLIEASGSQ--FEVLHGAEVIATIEWSLIGLHNVQNALAAISAAEHIGVAPTLACEAL 318
Cdd:TIGR01082 228 ITYGG--------SGEDADYRAENIQQSGAEgkFSVRGKGKLYLEFTLNLPGRHNVLNALAAIAVALELGIDFEAILRAL 299
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486244059 319 SHFEGIKRRMELRATVQNIAVYDDFAHHPTAISTTLAGLRKQVGDARIIAVLEPR--SNTMKLgtmSARLPASLQQADLL 396
Cdd:TIGR01082 300 ANFQGVKRRFEILGEFGGVLLIDDYAHHPTEIKATLKAARQGYPDKRIVVVFQPHrySRTRDL---FDDFAKVLSDADEL 376
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2486244059 397 FCynetqgkHSIHWDAERVFA---------TMSQPTEVH----HDLEQLVQAVAAAAQPGDHILVMSNGGFGGFHDKLI 462
Cdd:TIGR01082 377 IL-------LDIYAAGEEPINgidgkslarKITQLGKIEpyfvPDLAELVEFLAAVLQSGDLILTMGAGDIIKLARELL 448
|
|
| PRK14573 |
PRK14573 |
bifunctional UDP-N-acetylmuramate--L-alanine ligase/D-alanine--D-alanine ligase; |
1-372 |
2.27e-43 |
|
bifunctional UDP-N-acetylmuramate--L-alanine ligase/D-alanine--D-alanine ligase;
Pssm-ID: 184752 [Multi-domain] Cd Length: 809 Bit Score: 163.45 E-value: 2.27e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486244059 1 MHIHILGICGTFMGGLALIARAAGHRVTGCDMAvYPPMSTQLEEQGIELIEGYGAEQLalkPD--LFIIGNVVSRGNPLM 78
Cdd:PRK14573 5 LFYHFIGIGGIGMSALAHILLDRGYSVSGSDLS-EGKTVEKLKAKGARFFLGHQEEHV---PEdaVVVYSSSISKDNVEY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486244059 79 EAILNEGLPFTSGPQWLGEqILRQQHVLAIAGTHGKTTTSSMLAWILQYAGLAPNFLIGGIAQNfGISArFDAAQRYFVI 158
Cdd:PRK14573 81 LSAKSRGNRLVHRAELLAE-LMQEQISILVSGSHGKTTVSSLITAIFQEAKKDPSYAIGGLNQE-GLNG-YSGSSEYFVA 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486244059 159 EADEYDTAffdkrskFVHYRPRTAVLNNLEFDHADIF----ENLAAIQKQFhhlVRIIPQQGRVIYPAADQALQevlamG 234
Cdd:PRK14573 158 EADESDGS-------LKHYTPEFSVITNIDNEHLSNFegdrELLLASIQDF---ARKVQQINKCFYNGDCPRLK-----G 222
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486244059 235 C-------WSEQCSLgsglaHEHDHASDpkaTWNvrlieasgSQFEVLHGAEVIATIEWSLIGLHNVQNALAAISAAEHI 307
Cdd:PRK14573 223 ClqghsygFSSSCDL-----HILSYYQE---GWR--------SYFSAKFLGVVYQDIELNLVGMHNVANAAAAMGIALTL 286
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2486244059 308 GVAPTLACEALSHFEGIKRRMELRATVQNIAVYDDFAHHPTAISTTLAGLRKQVGDARIIAVLEP 372
Cdd:PRK14573 287 GIDEGAIRNALKGFSGVQRRLERKNSSETFLFLEDYAHHPSEISCTLRAVRDAVGLRRIIAICQP 351
|
|
| MurD |
COG0771 |
UDP-N-acetylmuramoylalanine-D-glutamate ligase [Cell wall/membrane/envelope biogenesis]; ... |
1-342 |
5.16e-29 |
|
UDP-N-acetylmuramoylalanine-D-glutamate ligase [Cell wall/membrane/envelope biogenesis]; UDP-N-acetylmuramoylalanine-D-glutamate ligase is part of the Pathway/BioSystem: Mureine biosynthesis
Pssm-ID: 440534 [Multi-domain] Cd Length: 445 Bit Score: 118.64 E-value: 5.16e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486244059 1 MHIHILGicgtfMG--GLALI--ARAAGHRVTGCDMAVYPPMS-TQLEEQGIELIEGYGAEQLALKPDLFII--GnvVSR 73
Cdd:COG0771 5 KKVLVLG-----LGksGLAAArlLAKLGAEVTVSDDRPAPELAaAELEAPGVEVVLGEHPEELLDGADLVVKspG--IPP 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486244059 74 GNPLMEAILNEGLPFTSGPQWLGEqiLRQQHVLAIAGTHGKTTTSSMLAWILQYAGLapNFLIGGiaqNFGISA----RF 149
Cdd:COG0771 78 DHPLLKAARAAGIPVIGEIELAYR--LSPAPIIAITGTNGKTTTTTLIGHILKAAGL--RVAVGG---NIGTPLldllLE 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486244059 150 DAAQRYFVIEAdeydtaffdkrSKF-----VHYRPRTAVLNNLEFDHADI---FENLAAIqKQfhhlvRIIPQQG---RV 218
Cdd:COG0771 151 PEPPDVYVLEL-----------SSFqlettPSLRPDVAVILNITPDHLDRhgsMEAYAAA-KA-----RIFANQTpddYA 213
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486244059 219 IYPAADQALQEvLAMGCWSEQCSLGSGLAHEHD-HASDPKATWNvrlieasgsqfevLHGAEVIATIEWSLIGLHNVQNA 297
Cdd:COG0771 214 VLNADDPLTRA-LAEEAKARVVPFSLKEPLEGGaGLEDGKLVDR-------------ASGEELLPVDDLRLPGRHNLENA 279
|
330 340 350 360
....*....|....*....|....*....|....*....|....*
gi 2486244059 298 LAAISAAEHIGVAPTLACEALSHFEGIKRRMELRATVQNIAVYDD 342
Cdd:COG0771 280 LAALAAARALGVPPEAIREALRSFKGLPHRLEFVAEINGVRFIND 324
|
|
| MurE |
COG0769 |
UDP-N-acetylmuramyl tripeptide synthase [Cell wall/membrane/envelope biogenesis]; ... |
101-369 |
8.63e-24 |
|
UDP-N-acetylmuramyl tripeptide synthase [Cell wall/membrane/envelope biogenesis]; UDP-N-acetylmuramyl tripeptide synthase is part of the Pathway/BioSystem: Mureine biosynthesis
Pssm-ID: 440532 [Multi-domain] Cd Length: 459 Bit Score: 103.62 E-value: 8.63e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486244059 101 RQQHVLAIAGTHGKTTTSSMLAWILQYAGLaPNFLIGGIaqNFGISARFDAA----------QRYF-----------VIE 159
Cdd:COG0769 78 QKLKLIGVTGTNGKTTTTYLLAQILRALGK-KTGLIGTV--GNGIGGELIPSslttpealdlQRLLaemvdagvthvVME 154
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486244059 160 A-----DEYdtaffdkRSKFVHYRprTAVLNNLEFDHADI---FEN-LAAIQKQFHHLvriiPQQGRVIYPAADQALQEV 230
Cdd:COG0769 155 VsshalDQG-------RVDGVRFD--VAVFTNLTRDHLDYhgtMEAyFAAKARLFDQL----GPGGAAVINADDPYGRRL 221
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486244059 231 LAM---GCWSeqcslgsglahehdHASDPKATWNVRLIE--ASGSQFEvLHGAEVIATIEWSLIGLHNVQNALAAISAAE 305
Cdd:COG0769 222 AAAapaRVIT--------------YGLKADADLRATDIElsADGTRFT-LVTPGGEVEVRLPLIGRFNVYNALAAIAAAL 286
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2486244059 306 HIGVAPTLACEALSHFEGIKRRMELRATVQNIAVYDDFAHHPTAISTTLAGLRKQVGdARIIAV 369
Cdd:COG0769 287 ALGIDLEEILAALEKLKGVPGRMERVDGGQGPTVIVDYAHTPDALENVLEALRPHTK-GRLIVV 349
|
|
| murD |
TIGR01087 |
UDP-N-acetylmuramoylalanine--D-glutamate ligase; [Cell envelope, Biosynthesis and degradation ... |
2-361 |
1.01e-21 |
|
UDP-N-acetylmuramoylalanine--D-glutamate ligase; [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273436 [Multi-domain] Cd Length: 433 Bit Score: 97.03 E-value: 1.01e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486244059 2 HIHILGICGTfmgGLALIA--RAAGHRVTGCDMAVY--PPMSTQLEE--QGIELIEGYGAEQLaLKPDLFIIGNVVSRGN 75
Cdd:TIGR01087 1 KILILGLGKT---GRAVARflHKKGAEVTVTDLKPNeeLEPSMGQLRlnEGSVLHTGLHLEDL-NNADLVVKSPGIPPDH 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486244059 76 PLMEAILNEGLPFTSGPQWLGEqiLRQQHVLAIAGTHGKTTTSSMLAWILQYAGLapNFLIGGiaqNFGISA---RFDAA 152
Cdd:TIGR01087 77 PLVQAAAKRGIPVVGDIELFLR--LVPLPVVAITGTNGKTTTTSLLYHLLKAAGL--KAFLGG---NIGTPAlevLDQEG 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486244059 153 QRYFVIEAdeydtaffdkrSKF-VHY----RPRTAVLNNLEFDHADI---FEN-LAAIQKQFHHL----VRIIPQQG-RV 218
Cdd:TIGR01087 150 AELYVLEL-----------SSFqLETteslRPEIALILNISEDHLDWhgsFEDyVAAKLKIFARQtegdVAVLNADDpRF 218
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486244059 219 IYPAADQALQEVLamgcWSEQCSLGSGLAHEHDHasdpkatwnvrlieasgsqfEVLHGAEVIAtiewSLIGLHNVQNAL 298
Cdd:TIGR01087 219 ARLAQKSKAQVIW----FSVEKDAERGLCIRDGG--------------------LYLKPNDLEG----SLLGLHNAENIL 270
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2486244059 299 AAISAAEHIGVAPTLACEALSHFEGIKRRMELRATVQNIAVYDDF-AHHPTAISTTLAGLRKQV 361
Cdd:TIGR01087 271 AAIALAKSLGLNLEAILEALRSFKGLPHRLEYVGQKNGVHFYNDSkATNVHATLAALSAFDNPV 334
|
|
| MurF |
COG0770 |
UDP-N-acetylmuramyl pentapeptide synthase [Cell wall/membrane/envelope biogenesis]; ... |
101-448 |
1.29e-20 |
|
UDP-N-acetylmuramyl pentapeptide synthase [Cell wall/membrane/envelope biogenesis]; UDP-N-acetylmuramyl pentapeptide synthase is part of the Pathway/BioSystem: Mureine biosynthesis
Pssm-ID: 440533 [Multi-domain] Cd Length: 451 Bit Score: 94.01 E-value: 1.29e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486244059 101 RQQH---VLAIAGTHGKTTTSSMLAWIL--QYAGLAPnfliggiAQNF----GIS---ARFDAAQRYFVIEA-------- 160
Cdd:COG0770 95 RARFnipVIAITGSNGKTTTKEMLAAVLstKGKVLAT-------PGNFnneiGVPltlLRLPEDHEFAVLEMgmnhpgei 167
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486244059 161 DEYdtaffdkrSKFVhyRPRTAVLNNLEFDHADIFENLAAIQKQ----FHHLvriiPQQGRVIYPAADQALQEvlamgcW 236
Cdd:COG0770 168 AYL--------ARIA--RPDIAVITNIGPAHLEGFGSLEGIARAkgeiFEGL----PPGGVAVLNADDPLLAA------L 227
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486244059 237 SEQCS---LGSGLAHEHD-HASDPKATwnvrlieASGSQFEVLHGAEVIaTIEWSLIGLHNVQNALAAISAAEHIGVAPT 312
Cdd:COG0770 228 AERAKarvLTFGLSEDADvRAEDIELD-------EDGTRFTLHTPGGEL-EVTLPLPGRHNVSNALAAAAVALALGLDLE 299
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486244059 313 LACEALSHFEGIKRRMELRATVQNIAVYDDfAHH--PTAISTTLAGLRKQVGDARIIAVLeprsNTMK-LGTMSARL--- 386
Cdd:COG0770 300 EIAAGLAAFQPVKGRLEVIEGAGGVTLIDD-SYNanPDSMKAALDVLAQLPGGGRRIAVL----GDMLeLGEESEELhre 374
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2486244059 387 ---PASLQQADLLFCYnetqGKHSihwdaeRVFATMSQPTEVHH--DLEQLVQAVAAAAQPGDHILV 448
Cdd:COG0770 375 vgeLAAELGIDRLFTV----GELA------RAIAEAAGGERAEHfeDKEELLAALKALLRPGDVVLV 431
|
|
| Mur_ligase_M |
pfam08245 |
Mur ligase middle domain; |
108-304 |
5.77e-19 |
|
Mur ligase middle domain;
Pssm-ID: 462409 [Multi-domain] Cd Length: 199 Bit Score: 84.66 E-value: 5.77e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486244059 108 IAGTHGKTTTSSMLAWILQYAGLA---PNFLIGGIAQNF----GISARFDAAQR----YFVIEADEYdtAFFDKRSKFVh 176
Cdd:pfam08245 1 VTGTNGKTTTTELIAAILSLAGGVigtIGTYIGKSGNTTnnaiGLPLTLAEMVEagaeYAVLEVSSH--GLGEGRLSGL- 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486244059 177 YRPRTAVLNNLEFDHADIFENLAAIQKQFHHLVRIIPQQGRVIYPAADQALQEVLAMGCWSEQCSLGSGLAHEHD-HASD 255
Cdd:pfam08245 78 LKPDIAVFTNISPDHLDFHGTMENYAKAKAELFEGLPEDGIAVINADDPYGAFLIAKLKKAGVRVITYGIEGEADlRAAN 157
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 2486244059 256 PKATWnvrlieaSGSQFEVLHGAEVIATIEWSLIGLHNVQNALAAISAA 304
Cdd:pfam08245 158 IELSS-------DGTSFDLFTVPGGELEIEIPLLGRHNVYNALAAIAAA 199
|
|
| PRK11929 |
PRK11929 |
bifunctional UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase MurE ... |
105-342 |
4.55e-16 |
|
bifunctional UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase MurE/UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase MurF;
Pssm-ID: 237025 [Multi-domain] Cd Length: 958 Bit Score: 80.90 E-value: 4.55e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486244059 105 VLAIAGTHGKTTTSSMLAWILqyAGLAPNFLIGGIAQNF----GISA---RFDAAQRYFVIEADEYDTAFFDKRSKFVhy 177
Cdd:PRK11929 605 VVAITGSNGKTTTKEMIAAIL--AAWQGEDRVLATEGNFnneiGVPLtllRLRAQHRAAVFELGMNHPGEIAYLAAIA-- 680
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486244059 178 RPRTAVLNNLEFDHADIFENLAAIQKQFHHLVRIIPQQGRVIYPAADQALQEVLAMGCWSEQCS--LGSGLAHEHDHASD 255
Cdd:PRK11929 681 APTVALVTNAQREHQEFMHSVEAVARAKGEIIAALPEDGVAVVNGDDPYTAIWAKLAGARRVLRfgLQPGADVYAEKIAK 760
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486244059 256 PKATWnvrliEASGSQFEVLHGAEVIaTIEWSLIGLHNVQNALAAISAAEHIGVAPTLACEALSHFEGIKRRMELRATVQ 335
Cdd:PRK11929 761 DISVG-----EAGGTRCQVVTPAGSA-EVYLPLIGEHNLRNALAAIACALAAGASLKQIRAGLERFQPVAGRMQRRRLSC 834
|
....*..
gi 2486244059 336 NIAVYDD 342
Cdd:PRK11929 835 GTRIIDD 841
|
|
| murE |
PRK00139 |
UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase; Provisional |
101-369 |
4.98e-16 |
|
UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase; Provisional
Pssm-ID: 234660 [Multi-domain] Cd Length: 460 Bit Score: 80.18 E-value: 4.98e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486244059 101 RQQHVLAIAGTHGKTTTSSMLAWILQYAGL--ApnfLIGGIaQNFGISARFDAA---------QR-----------YFVI 158
Cdd:PRK00139 93 DKLKLIGVTGTNGKTTTAYLLAQILRLLGEktA---LIGTL-GNGIGGELIPSGlttpdaldlQRllaelvdagvtYAAM 168
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486244059 159 EA-----DEydtaffdKRSKFVHYRprTAVLNNLEFDHADI---FEN-LAAIQKQFHHLVRIipqqgRVIY---PAADQA 226
Cdd:PRK00139 169 EVsshalDQ-------GRVDGLKFD--VAVFTNLSRDHLDYhgtMEDyLAAKARLFSELGLA-----AVINaddEVGRRL 234
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486244059 227 LQEVLAMGcwseqcslgsglahehdhASDPKATWNVRLIE--ASGSQFEVLHgaeviaTIEWSLIGLHNVQNALAAISAA 304
Cdd:PRK00139 235 LALPDAYA------------------VSMAGADLRATDVEytDSGQTFTLVT------EVESPLIGRFNVSNLLAALAAL 290
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2486244059 305 EHIGVAPTLACEALSHFEGIKRRMELRATVQNIAVYDDFAHHPTAISTTLAGLRKQVgDARIIAV 369
Cdd:PRK00139 291 LALGVPLEDALAALAKLQGVPGRMERVDAGQGPLVIVDYAHTPDALEKVLEALRPHA-KGRLICV 354
|
|
| murD |
PRK14106 |
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional |
15-342 |
5.46e-16 |
|
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional
Pssm-ID: 184511 [Multi-domain] Cd Length: 450 Bit Score: 80.01 E-value: 5.46e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486244059 15 GLALIAR--AAGHRVTGCDMAVYPPMSTQLEE---QGIELIEGYGAEQLALKPDLFiignVVSRGNPLMEAILNEGLPFt 89
Cdd:PRK14106 17 GLALAKFlkKLGAKVILTDEKEEDQLKEALEElgeLGIELVLGEYPEEFLEGVDLV----VVSPGVPLDSPPVVQAHKK- 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486244059 90 sGPQWLGEQIL----RQQHVLAIAGTHGKTTTSSMLAWILQYAGLapNFLIGGiaqNFGISarfdaaqryFVIEADEY-- 163
Cdd:PRK14106 92 -GIEVIGEVELayrfSKAPIVAITGTNGKTTTTTLLGEIFKNAGR--KTLVAG---NIGYP---------LIDAVEEYge 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486244059 164 DTAFFDKRSKF-----VHYRPRTAVLNNLEFDHAD---IFENLAAIQkqfhhlVRIIPQQGR-----------VIYPAAD 224
Cdd:PRK14106 157 DDIIVAEVSSFqletiKEFKPKVGCILNITPDHLDrhkTMENYIKAK------ARIFENQRPsdytvlnyddpRTRSLAK 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486244059 225 QALQEVLAmgcWSEQCSLGSGLAHEHDhasdpkatwnvrLIEASGSQfevlHGAEVIATIEWSLIGLHNVQNALAAISAA 304
Cdd:PRK14106 231 KAKARVIF---FSRKSLLEEGVFVKNG------------KIVISLGG----KEEEVIDIDEIFIPGEHNLENALAATAAA 291
|
330 340 350
....*....|....*....|....*....|....*...
gi 2486244059 305 EHIGVAPTLACEALSHFEGIKRRMELRATVQNIAVYDD 342
Cdd:PRK14106 292 YLLGISPDVIANTLKTFKGVEHRIEFVAEINGVKFIND 329
|
|
| Mur_ligase |
pfam01225 |
Mur ligase family, catalytic domain; This family contains a number of related ligase enzymes ... |
2-97 |
5.54e-16 |
|
Mur ligase family, catalytic domain; This family contains a number of related ligase enzymes which have EC numbers 6.3.2.*. This family includes: MurC, MurD, MurE, MurF, Mpl and FolC. MurC, MurD, Mure and MurF catalyze consecutive steps in the synthesis of peptidoglycan. Peptidoglycan consists of a sheet of two sugar derivatives, with one of these N-acetylmuramic acid attaching to a small pentapeptide. The pentapeptide is is made of L-alanine, D-glutamic acid, Meso-diaminopimelic acid and D-alanyl alanine. The peptide moiety is synthesized by successively adding these amino acids to UDP-N-acetylmuramic acid. MurC transfers the L-alanine, MurD transfers the D-glutamate, MurE transfers the diaminopimelic acid, and MurF transfers the D-alanyl alanine. This family also includes Folylpolyglutamate synthase that transfers glutamate to folylpolyglutamate.
Pssm-ID: 460121 [Multi-domain] Cd Length: 84 Bit Score: 72.65 E-value: 5.54e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486244059 2 HIHILGICGTFMGGLALIARAAGHRVTGCDMAVYppmstqLEEQGIELIEGYGAEqlalkpdlfiigNVVSRGNPLMEAI 81
Cdd:pfam01225 1 EIHFVGIDGRGMSPGALFLALKGYRVDGSDFIES------LIALGAAAVVGHDAA------------NNISPDNPELEAA 62
|
90
....*....|....*.
gi 2486244059 82 LNEGLPFTSGPQWLGE 97
Cdd:pfam01225 63 KVPGIPVIDRREALAE 78
|
|
| murE |
TIGR01085 |
UDP-N-acetylmuramyl-tripeptide synthetase; Most members of this family are EC 6.3.2.13, ... |
105-369 |
5.87e-13 |
|
UDP-N-acetylmuramyl-tripeptide synthetase; Most members of this family are EC 6.3.2.13, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase. An exception is Staphylococcus aureus, in which diaminopimelate is replaced by lysine in the peptidoglycan and MurE is EC 6.3.2.7. The Mycobacteria, part of the closest neighboring branch outside of the low-GC Gram-positive bacteria, use diaminopimelate. A close homolog, scoring just below the trusted cutoff, is found (with introns) in Arabidopsis thaliana. Its role is unknown. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273435 [Multi-domain] Cd Length: 464 Bit Score: 70.42 E-value: 5.87e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486244059 105 VLAIAGTHGKTTTSSMLAWILQYAGLAPNFlIGGIAQNFG--ISARFDAAQ--------------------RYFVIEADE 162
Cdd:TIGR01085 87 VIGVTGTNGKTTTTSLIAQLLRLLGKKTGL-IGTIGYRLGgnDLIKNPAALttpealtlqstlaemveagaQYAVMEVSS 165
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486244059 163 YdtAFFDKRSKFVHYRprTAVLNNLEFDHADI---FENLAAIQKqfhHLVRIIPQQGRVIYPAADQALQEvlamgcwseq 239
Cdd:TIGR01085 166 H--ALAQGRVRGVRFD--AAVFTNLSRDHLDFhgtMENYFAAKA---SLFTELGLKRFAVINLDDEYGAQ---------- 228
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486244059 240 csLGSGLAHE-HDHASDPKATWNVRLIE--ASGSQFEVLHGAEV----IATIEWSLIGLHNVQNALAAISAAEHIGVAPT 312
Cdd:TIGR01085 229 --FVKRLPKDiTVSAITQPADGRAQDIKitDSGYSFEGQQFTFEtpagEGHLHTPLIGRFNVYNLLAALATLLHLGGIDL 306
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*...
gi 2486244059 313 LA-CEALSHFEGIKRRMELRATVQNIAVYDDFAHHPTAISTTLAGLRKqVGDARIIAV 369
Cdd:TIGR01085 307 EDiVAALEKFRGVPGRMELVDGGQKFLVIVDYAHTPDALEKALRTLRK-HKDGRLIVV 363
|
|
| PRK11929 |
PRK11929 |
bifunctional UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase MurE ... |
105-369 |
1.24e-12 |
|
bifunctional UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase MurE/UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase MurF;
Pssm-ID: 237025 [Multi-domain] Cd Length: 958 Bit Score: 70.12 E-value: 1.24e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486244059 105 VLAIAGTHGKTTTSSMLAWILQYAG-----------LAPNFLIGG--------IAQNfgISARF-DAAQRYFVIEADEYD 164
Cdd:PRK11929 114 LVAVTGTNGKTSCAQLLAQLLTRLGkpcgsigtlgaRLDGRLIPGslttpdaiILHR--ILARMrAAGADAVAMEASSHG 191
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486244059 165 TaffdKRSKFVHYRPRTAVLNNLEFDHADIFENLAAIQKQFHHLVRIIPQQGRVIYPAADQALQEVLAMGCWSEQCSLGS 244
Cdd:PRK11929 192 L----EQGRLDGLRIAVAGFTNLTRDHLDYHGTMQDYEEAKAALFSKLPGLGAAVINADDPAAARLLAALPRGLKVGYSP 267
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486244059 245 GLAHEHDHASDPKATwnvrlieASGSQFEVLHGAEViATIEWSLIGLHNVQNALAAISAAEHIGVAPTLACEALSHFEGI 324
Cdd:PRK11929 268 QNAGADVQARDLRAT-------AHGQVFTLATPDGS-YQLVTRLLGRFNVSNLLLVAAALKKLGLPLAQIARALAAVSPV 339
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|
gi 2486244059 325 KRRME---LRATVQNIAVYDDFAHHPTAISTTLAGLR--KQVGDARIIAV 369
Cdd:PRK11929 340 PGRMErvgPTAGAQGPLVVVDYAHTPDALAKALTALRpvAQARNGRLVCV 389
|
|
| murF |
TIGR01143 |
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; This family consists of the ... |
105-342 |
6.86e-08 |
|
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; This family consists of the strictly bacterial MurF gene of peptidoglycan biosynthesis. This enzyme is almost always UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase, but in a few species, MurE adds lysine rather than diaminopimelate. This enzyme acts on the product from MurE activity, and so is also subfamily rather than equivalog. Staphylococcus aureus is an example of species in this MurF protein would differ. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273468 [Multi-domain] Cd Length: 417 Bit Score: 54.58 E-value: 6.86e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486244059 105 VLAIAGTHGKTTTSSMLAWILQ--YAGLAPNfliGGIAQNFGIS---ARFDAAQRYFVIE---------ADEYDTAffdk 170
Cdd:TIGR01143 76 VIGITGSSGKTTTKEMLAAILShkYKVFATP---GNFNNEIGLPltlLRAPGDHDYAVLEmgashpgeiAYLAEIA---- 148
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486244059 171 rskfvhyRPRTAVLNNLEFDHADIFENLAAIQKQFHHLVRIIPQQGRVIYPAADQALQevlamgcWSEQCSLGSGLAHEH 250
Cdd:TIGR01143 149 -------KPDIAVITNIGPAHLEGFGSLEGIAEAKGEILQGLKENGIAVINADDPAFA-------DLAKRLPNRNILSFG 214
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486244059 251 DHASDPKATwNVRLIEASGSQFeVLHGAEVIATIEWSLIGLHNVQNALAAISAAEHIGVAPTLACEALSHFEGIKRRMEL 330
Cdd:TIGR01143 215 FEGGDFVAK-DISYSALGSTSF-TLVAPGGEFEVSLPLLGRHNVMNALAAAALALELGIPLEEIAEGLAELKLVKGRFEV 292
|
250
....*....|..
gi 2486244059 331 RaTVQNIAVYDD 342
Cdd:TIGR01143 293 Q-TKNGLTLIDD 303
|
|
| Mur_ligase_C |
pfam02875 |
Mur ligase family, glutamate ligase domain; This family contains a number of related ligase ... |
324-370 |
2.68e-07 |
|
Mur ligase family, glutamate ligase domain; This family contains a number of related ligase enzymes which have EC numbers 6.3.2.*. This family includes: MurC, MurD, MurE, MurF, Mpl and FolC. MurC, MurD, Mure and MurF catalyze consecutive steps in the synthesis of peptidoglycan. Peptidoglycan consists of a sheet of two sugar derivatives, with one of these N-acetylmuramic acid attaching to a small pentapeptide. The pentapeptide is is made of L-alanine, D-glutamic acid, Meso-diaminopimelic acid and D-alanyl alanine. The peptide moiety is synthesized by successively adding these amino acids to UDP-N-acetylmuramic acid. MurC transfers the L-alanine, MurD transfers the D-glutamate, MurE transfers the diaminopimelic acid, and MurF transfers the D-alanyl alanine. This family also includes Folylpolyglutamate synthase that transfers glutamate to folylpolyglutamate.
Pssm-ID: 460731 [Multi-domain] Cd Length: 87 Bit Score: 48.11 E-value: 2.68e-07
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 2486244059 324 IKRRMELRATVQNIAVYDDFAHHPTAISTTLAGLRkQVGDARIIAVL 370
Cdd:pfam02875 1 VPGRLEVVGENNGVLVIDDYAHNPDAMEAALRALR-NLFPGRLILVF 46
|
|
| PRK14093 |
PRK14093 |
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase; ... |
105-398 |
3.93e-07 |
|
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase; Provisional
Pssm-ID: 184501 [Multi-domain] Cd Length: 479 Bit Score: 52.47 E-value: 3.93e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486244059 105 VLAIAGTHGKTTTSSMLAWILQYAGlAPNFLIGGIAQNFGIS---ARFDAAQRYFVIEADEYDTAFFDKRSKFVhyRPRT 181
Cdd:PRK14093 110 VIAVTGSVGKTSTKEALRGVLGAQG-ETHASVASFNNHWGVPlslARCPADARFAVFEIGMNHAGEIEPLVKMV--RPHV 186
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486244059 182 AVLNNLEFDHADIFENLAAIQKQFHHLVRIIPQQGRVIYpAADQALQEVLAmgcwseQCSLGSGLAHEHDHASDPKAtwN 261
Cdd:PRK14093 187 AIITTVEPVHLEFFSGIEAIADAKAEIFTGLEPGGAAVL-NRDNPQFDRLA------ASARAAGIARIVSFGADEKA--D 257
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486244059 262 VRLI------EASGSQFEVLhGAEViaTIEWSLIGLHNVQNALAAISAAEHIGVAPTLACEALSHFE-----GIKRRMEL 330
Cdd:PRK14093 258 ARLLdvalhaDCSAVHADIL-GHDV--TYKLGMPGRHIAMNSLAVLAAAELAGADLALAALALSQVQpaagrGVRHTLEV 334
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2486244059 331 R---ATVqniaVYDDFAHHPTAISTTLAGL-RKQVG-DARIIAVLeprSNTMKLGTMSARLPASLQQA------DLLFC 398
Cdd:PRK14093 335 GggeATL----IDESYNANPASMAAALGVLgRAPVGpQGRRIAVL---GDMLELGPRGPELHRGLAEAiranaiDLVFC 406
|
|
| PRK14016 |
PRK14016 |
cyanophycin synthetase; Provisional |
105-322 |
4.93e-05 |
|
cyanophycin synthetase; Provisional
Pssm-ID: 237586 [Multi-domain] Cd Length: 727 Bit Score: 45.92 E-value: 4.93e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486244059 105 VLAIAGTHGKTTTSSMLAWILQYAGlapnfLIGGIAQNFGI----------------SARF-------DAAqryfVIEad 161
Cdd:PRK14016 482 IVAVTGTNGKTTTTRLIAHILKLSG-----KRVGMTTTDGVyidgrlidkgdctgpkSARRvlmnpdvEAA----VLE-- 550
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486244059 162 eydTAF---------FDkrskfvhyRPRTAVLNNLEFDHADIF-----ENLAaiqkqfhHLVRIIPQ------------- 214
Cdd:PRK14016 551 ---TARggilreglaYD--------RCDVGVVTNIGEDHLGLGgintlEDLA-------KVKRVVVEavkpdgyavlnad 612
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486244059 215 -----------QGRVIYPAADQALqEVLAmgcwsEQCSLGsGLA--HEHDHASDPKATWNVRLIEAsgsqfevlhgAEVI 281
Cdd:PRK14016 613 dpmvaamaercKGKVIFFSMDPDN-PVIA-----EHRAQG-GRAvyVEGDYIVLAEGGWEIRIISL----------ADIP 675
|
250 260 270 280
....*....|....*....|....*....|....*....|.
gi 2486244059 282 ATIEWSLIglHNVQNALAAISAAEHIGVAPTLACEALSHFE 322
Cdd:PRK14016 676 LTLGGKAG--FNIENALAAIAAAWALGIDIELIRAGLRTFV 714
|
|
| FolC |
COG0285 |
Folylpolyglutamate synthase/Dihydropteroate synthase [Coenzyme transport and metabolism]; ... |
108-370 |
7.29e-03 |
|
Folylpolyglutamate synthase/Dihydropteroate synthase [Coenzyme transport and metabolism]; Folylpolyglutamate synthase/Dihydropteroate synthase is part of the Pathway/BioSystem: Folate biosynthesis
Pssm-ID: 440054 [Multi-domain] Cd Length: 423 Bit Score: 38.55 E-value: 7.29e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486244059 108 IAGTHGKTTTSSMLAWILQYAGL------------------------APNFLIGGIAQNFGISARFDAAQ---------- 153
Cdd:COG0285 45 VAGTNGKGSTAAMLESILRAAGYrvglytsphlvrfneriringepiSDEELVEALEEVEPAVEEVDAGPptffevttaa 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486244059 154 --RYF--------VIEAD---EYD-TAFFDkrskfvhyrPRTAVLNNLEFDHADIF-ENLAAI--QKqfhhlVRIIPQQG 216
Cdd:COG0285 125 afLYFaeapvdvaVLEVGlggRLDaTNVID---------PLVSVITSIGLDHTDFLgDTLEEIarEK-----AGIIKPGV 190
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486244059 217 RVIYPAADQALQEVLAmgcwsEQC-SLGSGLAHEHDHasdpkatWNVRliEASGSQFEVLHGAEVIATIEWSLIGLHNVQ 295
Cdd:COG0285 191 PVVTGDQQPEALEVIE-----ERAaELGAPLYRAGRD-------FSVE--EREGAVFSYQGPGGEYEDLPLPLLGAHQAE 256
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2486244059 296 NALAAISAAEHI-GVAPTLACEALShfEGIKR-----RMELRAtvQNIAVYDDFAHHPTAISTTLAGLRKQVGDARIIAV 369
Cdd:COG0285 257 NAALALAALEALrELGLPISEEAIR--EGLANarwpgRLEVLS--RGPLVILDGAHNPAGARALAETLKELFPFRKLHLV 332
|
.
gi 2486244059 370 L 370
Cdd:COG0285 333 F 333
|
|
| |
