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Conserved domains on  [gi|2495360896|ref|WP_279655871|]
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MULTISPECIES: FAD-binding oxidoreductase [unclassified Agrobacterium]

Protein Classification

NAD(P)/FAD-dependent oxidoreductase( domain architecture ID 11429741)

FAD/NAD(P)-binding oxidoreductase that catalyzes the transfer of electrons from one molecule, the electron donor or reductant, to another molecule, the electron acceptor or oxidant

CATH:  3.30.9.10
EC:  1.-.-.-
Gene Ontology:  GO:0016491|GO:0050660
SCOP:  3000055

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DadA COG0665
Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];
6-415 1.48e-85

Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];


:

Pssm-ID: 440429 [Multi-domain]  Cd Length: 364  Bit Score: 265.23  E-value: 1.48e-85
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495360896   6 KCDVLVIGTGIIGSMAALYLQNAGREVVFLERGEVARGASSGNAGILAfpeiipipapgimkkaprwlfdplgplsvpPA 85
Cdd:COG0665     2 TADVVVIGGGIAGLSTAYHLARRGLDVTVLERGRPGSGASGRNAGQLR------------------------------PG 51

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495360896  86 YAHKIAPWLWRFWRASAERnfrhglksladinrlaameMAHVAAMPELSHLVSKTGTLDLYDSEASLNAARRDWDEKASA 165
Cdd:COG0665    52 LAALADRALVRLAREALDL-------------------WRELAAELGIDCDFRRTGVLYLARTEAELAALRAEAEALRAL 112

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495360896 166 GFSFERVGRSEIEALQPGLA-PQFRHAMFSPDGLQVsDPYDFTRAIFDLVLARGASLRKG-EAERIDAVGES-TIVTLEN 242
Cdd:COG0665   113 GLPVELLDAAELREREPGLGsPDYAGGLYDPDDGHV-DPAKLVRALARAARAAGVRIREGtPVTGLEREGGRvTGVRTER 191

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495360896 243 GDkIDADKVVIACGAWSRKLAATLGNIVPLETERGYNTTLPPEAFNLTRQLYFnDHGFVVTPLSTG-IRVGGAVELGGLE 321
Cdd:COG0665   192 GT-VRADAVVLAAGAWSARLLPMLGLRLPLRPVRGYVLVTEPLPDLPLRPVLD-DTGVYLRPTADGrLLVGGTAEPAGFD 269

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495360896 322 LKPNFRRAEAMLKKAGRFLPGLK-LEGGRQWMGFRPSMPDCLPVIGTARATPSVIYAFGHGHLGLTQSAATARLVTQLAS 400
Cdd:COG0665   270 RAPTPERLEALLRRLRRLFPALAdAEIVRAWAGLRPMTPDGLPIIGRLPGAPGLYVATGHGGHGVTLAPAAGRLLADLIL 349

                         410
                  ....*....|....*
gi 2495360896 401 GEETAISVDPFRPGR 415
Cdd:COG0665   350 GGEPPLDLAPFSPDR 364
 
Name Accession Description Interval E-value
DadA COG0665
Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];
6-415 1.48e-85

Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];


Pssm-ID: 440429 [Multi-domain]  Cd Length: 364  Bit Score: 265.23  E-value: 1.48e-85
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495360896   6 KCDVLVIGTGIIGSMAALYLQNAGREVVFLERGEVARGASSGNAGILAfpeiipipapgimkkaprwlfdplgplsvpPA 85
Cdd:COG0665     2 TADVVVIGGGIAGLSTAYHLARRGLDVTVLERGRPGSGASGRNAGQLR------------------------------PG 51

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495360896  86 YAHKIAPWLWRFWRASAERnfrhglksladinrlaameMAHVAAMPELSHLVSKTGTLDLYDSEASLNAARRDWDEKASA 165
Cdd:COG0665    52 LAALADRALVRLAREALDL-------------------WRELAAELGIDCDFRRTGVLYLARTEAELAALRAEAEALRAL 112

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495360896 166 GFSFERVGRSEIEALQPGLA-PQFRHAMFSPDGLQVsDPYDFTRAIFDLVLARGASLRKG-EAERIDAVGES-TIVTLEN 242
Cdd:COG0665   113 GLPVELLDAAELREREPGLGsPDYAGGLYDPDDGHV-DPAKLVRALARAARAAGVRIREGtPVTGLEREGGRvTGVRTER 191

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495360896 243 GDkIDADKVVIACGAWSRKLAATLGNIVPLETERGYNTTLPPEAFNLTRQLYFnDHGFVVTPLSTG-IRVGGAVELGGLE 321
Cdd:COG0665   192 GT-VRADAVVLAAGAWSARLLPMLGLRLPLRPVRGYVLVTEPLPDLPLRPVLD-DTGVYLRPTADGrLLVGGTAEPAGFD 269

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495360896 322 LKPNFRRAEAMLKKAGRFLPGLK-LEGGRQWMGFRPSMPDCLPVIGTARATPSVIYAFGHGHLGLTQSAATARLVTQLAS 400
Cdd:COG0665   270 RAPTPERLEALLRRLRRLFPALAdAEIVRAWAGLRPMTPDGLPIIGRLPGAPGLYVATGHGGHGVTLAPAAGRLLADLIL 349

                         410
                  ....*....|....*
gi 2495360896 401 GEETAISVDPFRPGR 415
Cdd:COG0665   350 GGEPPLDLAPFSPDR 364
DAO pfam01266
FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: ...
 8-398 2.27e-49

FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: Glycerol-3-phosphate dehydrogenase EC:1.1.99.5, Sarcosine oxidase beta subunit EC:1.5.3.1, D-alanine oxidase EC:1.4.99.1, D-aspartate oxidase EC:1.4.3.1.


Pssm-ID: 426168 [Multi-domain]  Cd Length: 339  Bit Score: 170.66  E-value: 2.27e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495360896   8 DVLVIGTGIIGSMAALYLQNAGREVVFLERG-EVARGASSGNAGILAfpeiipipapgimkkaprwlfdplgplsvpPAY 86
Cdd:pfam01266   1 DVVVIGGGIVGLSTAYELARRGLSVTLLERGdDPGSGASGRNAGLIH------------------------------PGL 50

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495360896  87 AHKIAPWLWRFwrasaernfrhglksladiNRLAAMEMAHVAAMPELSHLVSKTGTLDLYDSEASlNAARRDWDEKASAG 166
Cdd:pfam01266  51 RYLEPSELARL-------------------ALEALDLWEELEEELGIDCGFRRCGVLVLARDEEE-EALEKLLAALRRLG 110

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495360896 167 FSFERVGRSEIEALQPGLaPQFRHAMFSPDGLQVsDPYDFTRAIFDLVLARGASLRKG-EAERIDAVGESTIVTLENgdk 245
Cdd:pfam01266 111 VPAELLDAEELRELEPLL-PGLRGGLFYPDGGHV-DPARLLRALARAAEALGVRIIEGtEVTGIEEEGGVWGVVTTG--- 185

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495360896 246 iDADKVVIACGAWSRkLAATLGNIVPLETERGYNTTLPPEAFNLTRQLYF-----NDHGFVVTPLSTGIRVGGAVELGGL 320
Cdd:pfam01266 186 -EADAVVNAAGAWAD-LLALPGLRLPVRPVRGQVLVLEPLPEALLILPVPitvdpGRGVYLRPRADGRLLLGGTDEEDGF 263

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2495360896 321 E-LKPNFRRAEAMLKKAGRFLPGLKlEGGRQWMGFRPsMPDCLPVIGTARAtPSVIYAFGHGHLGLTQSAATARLVTQL 398
Cdd:pfam01266 264 DdPTPDPEEIEELLEAARRLFPALA-DIERAWAGLRP-LPDGLPIIGRPGS-PGLYLATGHGGHGLTLAPGIGKLLAEL 339
PRK00711 PRK00711
D-amino acid dehydrogenase;
9-416 1.95e-46

D-amino acid dehydrogenase;


Pssm-ID: 234819 [Multi-domain]  Cd Length: 416  Bit Score: 164.59  E-value: 1.95e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495360896   9 VLVIGTGIIGSMAALYLQNAGREVVFLER-GEVARGASSGNAGILAFPEIIPIPAPGIMKKAPRWLFDPLGPLSVPPAYA 87
Cdd:PRK00711    3 VVVLGSGVIGVTSAWYLAQAGHEVTVIDRqPGPALETSFANAGQISPGYAAPWAAPGVPLKAIKWLFQRHAPLAIRPDGD 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495360896  88 HKIAPWLWRFWRA-SAERnfrhglkslADIN-----RLAamE-----MAHVAAMPELSHLVSKTGTLDLYDSEASLNAAR 156
Cdd:PRK00711   83 PFQLRWMWQMLRNcTASR---------YAVNksrmvRLA--EysrdcLKALRAETGIQYEGRQGGTLQLFRTQQQLDAAA 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495360896 157 RDWDEKASAGFSFERVGRSEIEALQPGLAPqFRH----AMFSPDGlQVSDPYDFTRAIFDLVLARGASLRKG-EAERIDA 231
Cdd:PRK00711  152 KDIAVLEEAGVPYELLDRDELAAVEPALAG-VRHklvgGLRLPND-ETGDCQLFTQRLAAMAEQLGVKFRFNtPVDGLLV 229

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495360896 232 VGESTIVTLENGDKIDADKVVIACGAWSRKLAATLGNIVPLETERGYNTTLP-------PEAFNL--TRQLyfndhgfVV 302
Cdd:PRK00711  230 EGGRITGVQTGGGVITADAYVVALGSYSTALLKPLGVDIPVYPLKGYSLTVPitdedraPVSTVLdeTYKI-------AI 302

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495360896 303 TPLSTGIRVGGAVELGGLELKPNFRRAEAMLKKAGRFLPGlkleGGRQ-----WMGFRPSMPDCLPVIGtarATPsviYA 377
Cdd:PRK00711  303 TRFDDRIRVGGMAEIVGFDLRLDPARRETLEMVVRDLFPG----GGDLsqatfWTGLRPMTPDGTPIVG---ATR---YK 372

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....
gi 2495360896 378 -----FGHGHLGLTQSAATARLVTQLASGEETAISVDPFRPGRF 416
Cdd:PRK00711  373 nlwlnTGHGTLGWTMACGSGQLLADLISGRKPAIDADDLSVARY 416
soxA_mon TIGR01377
sarcosine oxidase, monomeric form; Sarcosine oxidase catalyzes the oxidative demethylation of ...
 8-417 2.40e-07

sarcosine oxidase, monomeric form; Sarcosine oxidase catalyzes the oxidative demethylation of sarcosine to glycine. The reaction converts tetrahydrofolate to 5,10-methylene-tetrahydrofolate. The enzyme is known in monomeric and heterotetrameric (alpha,beta,gamma,delta) forms [Energy metabolism, Amino acids and amines]


Pssm-ID: 130444 [Multi-domain]  Cd Length: 380  Bit Score: 52.52  E-value: 2.40e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495360896   8 DVLVIGTGIIGSMAALYLQNAGREVVFLERGEV--ARGASSGNAGIL--AFPEIIPIPapgIMKKAPRwlfdplgplsvp 83
Cdd:TIGR01377   2 DVIVVGAGIMGCFAAYHLAKHGKKTLLLEQFDLphSRGSSHGQSRIIrkAYPEDFYTP---MMLECYQ------------ 66

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495360896  84 payahkiapwLWrfwrASAERNFRHGLKSLADinrLAAMEMAHVAAMPELSHLVSKTGTL-DLYDSEAslnaarrdwdek 162
Cdd:TIGR01377  67 ----------LW----AQLEKEAGTKLHRQTG---LLLLGPKENQFLKTIQATLSRHGLEhELLSSKQ------------ 117

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495360896 163 ASAGFSFERVGRSEIealqpglapqfrhAMFSPDGlQVSDPYDFTRAIFDLVLARGASLRKGEAERIDAVGESTIVTLEN 242
Cdd:TIGR01377 118 LKQRFPNIRVPRNEV-------------GLLDPNG-GVLYAEKALRALQELAEAHGATVRDGTKVVEIEPTELLVTVKTT 183

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495360896 243 GDKIDADKVVIACGAWSRKLAATLGNIVPLETER---GYNTTLPPEAFNLTrQLYFNDHGFVVTPLSTGIRVGGAVEL-- 317
Cdd:TIGR01377 184 KGSYQANKLVVTAGAWTSKLLSPLGIEIPLQPLRinvCYWREKEPGSYGVS-QAFPCFLVLGLNPHIYGLPSFEYPGLmk 262

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495360896 318 ----GGLELKPNFR--------RAEAMLKKAGR-FLPGLKLEGGRQWMGFRPSMPDCLPVIGTARATPSVIYAFG-HGHl 383
Cdd:TIGR01377 263 vyyhHGQQIDPDERdcpfgadiEDVQILRKFVRdHLPGLNGEPKKGEVCMYTNTPDEHFVIDLHPKYDNVVIGAGfSGH- 341

                         410       420       430
                  ....*....|....*....|....*....|....
gi 2495360896 384 GLTQSAATARLVTQLASGEETAISVDPFRPGRFS 417
Cdd:TIGR01377 342 GFKLAPVVGKILAELAMKLKPSYDLAIFSLNRFA 375
PBEF_like cd01569
pre-B-cell colony-enhancing factor (PBEF)-like. The mammalian members of this group of ...
 128-221 4.37e-03

pre-B-cell colony-enhancing factor (PBEF)-like. The mammalian members of this group of nicotinate phosphoribosyltransferases (NAPRTases) were originally identified as genes whose expression is upregulated upon activation in lymphoid cells. In general, nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting, reaction in the NAD salvage synthesis.


Pssm-ID: 238803 [Multi-domain]  Cd Length: 407  Bit Score: 39.18  E-value: 4.37e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495360896 128 AAMPELSHLVSKTGTldlyDSEASLNAARRDWDEKASAGFSFERVGRS---------EIEALQpGLAPQFRHAMFSpdgl 198
Cdd:cd01569   187 AALGGAAHLVNFKGT----DTIPALDAAYAYYYEDPMAGFSIPAAEHStmtawgrerELEAFR-NLLEQFGPGIVS---- 257

                          90       100       110
                  ....*....|....*....|....*....|
gi 2495360896 199 QVSDPYDFTRAIF-------DLVLARGASL 221
Cdd:cd01569   258 VVSDSYDFWNALTlwgprlkDEILARGGTL 287
 
Name Accession Description Interval E-value
DadA COG0665
Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];
6-415 1.48e-85

Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];


Pssm-ID: 440429 [Multi-domain]  Cd Length: 364  Bit Score: 265.23  E-value: 1.48e-85
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495360896   6 KCDVLVIGTGIIGSMAALYLQNAGREVVFLERGEVARGASSGNAGILAfpeiipipapgimkkaprwlfdplgplsvpPA 85
Cdd:COG0665     2 TADVVVIGGGIAGLSTAYHLARRGLDVTVLERGRPGSGASGRNAGQLR------------------------------PG 51

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495360896  86 YAHKIAPWLWRFWRASAERnfrhglksladinrlaameMAHVAAMPELSHLVSKTGTLDLYDSEASLNAARRDWDEKASA 165
Cdd:COG0665    52 LAALADRALVRLAREALDL-------------------WRELAAELGIDCDFRRTGVLYLARTEAELAALRAEAEALRAL 112

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495360896 166 GFSFERVGRSEIEALQPGLA-PQFRHAMFSPDGLQVsDPYDFTRAIFDLVLARGASLRKG-EAERIDAVGES-TIVTLEN 242
Cdd:COG0665   113 GLPVELLDAAELREREPGLGsPDYAGGLYDPDDGHV-DPAKLVRALARAARAAGVRIREGtPVTGLEREGGRvTGVRTER 191

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495360896 243 GDkIDADKVVIACGAWSRKLAATLGNIVPLETERGYNTTLPPEAFNLTRQLYFnDHGFVVTPLSTG-IRVGGAVELGGLE 321
Cdd:COG0665   192 GT-VRADAVVLAAGAWSARLLPMLGLRLPLRPVRGYVLVTEPLPDLPLRPVLD-DTGVYLRPTADGrLLVGGTAEPAGFD 269

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495360896 322 LKPNFRRAEAMLKKAGRFLPGLK-LEGGRQWMGFRPSMPDCLPVIGTARATPSVIYAFGHGHLGLTQSAATARLVTQLAS 400
Cdd:COG0665   270 RAPTPERLEALLRRLRRLFPALAdAEIVRAWAGLRPMTPDGLPIIGRLPGAPGLYVATGHGGHGVTLAPAAGRLLADLIL 349

                         410
                  ....*....|....*
gi 2495360896 401 GEETAISVDPFRPGR 415
Cdd:COG0665   350 GGEPPLDLAPFSPDR 364
DAO pfam01266
FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: ...
 8-398 2.27e-49

FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: Glycerol-3-phosphate dehydrogenase EC:1.1.99.5, Sarcosine oxidase beta subunit EC:1.5.3.1, D-alanine oxidase EC:1.4.99.1, D-aspartate oxidase EC:1.4.3.1.


Pssm-ID: 426168 [Multi-domain]  Cd Length: 339  Bit Score: 170.66  E-value: 2.27e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495360896   8 DVLVIGTGIIGSMAALYLQNAGREVVFLERG-EVARGASSGNAGILAfpeiipipapgimkkaprwlfdplgplsvpPAY 86
Cdd:pfam01266   1 DVVVIGGGIVGLSTAYELARRGLSVTLLERGdDPGSGASGRNAGLIH------------------------------PGL 50

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495360896  87 AHKIAPWLWRFwrasaernfrhglksladiNRLAAMEMAHVAAMPELSHLVSKTGTLDLYDSEASlNAARRDWDEKASAG 166
Cdd:pfam01266  51 RYLEPSELARL-------------------ALEALDLWEELEEELGIDCGFRRCGVLVLARDEEE-EALEKLLAALRRLG 110

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495360896 167 FSFERVGRSEIEALQPGLaPQFRHAMFSPDGLQVsDPYDFTRAIFDLVLARGASLRKG-EAERIDAVGESTIVTLENgdk 245
Cdd:pfam01266 111 VPAELLDAEELRELEPLL-PGLRGGLFYPDGGHV-DPARLLRALARAAEALGVRIIEGtEVTGIEEEGGVWGVVTTG--- 185

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495360896 246 iDADKVVIACGAWSRkLAATLGNIVPLETERGYNTTLPPEAFNLTRQLYF-----NDHGFVVTPLSTGIRVGGAVELGGL 320
Cdd:pfam01266 186 -EADAVVNAAGAWAD-LLALPGLRLPVRPVRGQVLVLEPLPEALLILPVPitvdpGRGVYLRPRADGRLLLGGTDEEDGF 263

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2495360896 321 E-LKPNFRRAEAMLKKAGRFLPGLKlEGGRQWMGFRPsMPDCLPVIGTARAtPSVIYAFGHGHLGLTQSAATARLVTQL 398
Cdd:pfam01266 264 DdPTPDPEEIEELLEAARRLFPALA-DIERAWAGLRP-LPDGLPIIGRPGS-PGLYLATGHGGHGLTLAPGIGKLLAEL 339
PRK00711 PRK00711
D-amino acid dehydrogenase;
9-416 1.95e-46

D-amino acid dehydrogenase;


Pssm-ID: 234819 [Multi-domain]  Cd Length: 416  Bit Score: 164.59  E-value: 1.95e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495360896   9 VLVIGTGIIGSMAALYLQNAGREVVFLER-GEVARGASSGNAGILAFPEIIPIPAPGIMKKAPRWLFDPLGPLSVPPAYA 87
Cdd:PRK00711    3 VVVLGSGVIGVTSAWYLAQAGHEVTVIDRqPGPALETSFANAGQISPGYAAPWAAPGVPLKAIKWLFQRHAPLAIRPDGD 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495360896  88 HKIAPWLWRFWRA-SAERnfrhglkslADIN-----RLAamE-----MAHVAAMPELSHLVSKTGTLDLYDSEASLNAAR 156
Cdd:PRK00711   83 PFQLRWMWQMLRNcTASR---------YAVNksrmvRLA--EysrdcLKALRAETGIQYEGRQGGTLQLFRTQQQLDAAA 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495360896 157 RDWDEKASAGFSFERVGRSEIEALQPGLAPqFRH----AMFSPDGlQVSDPYDFTRAIFDLVLARGASLRKG-EAERIDA 231
Cdd:PRK00711  152 KDIAVLEEAGVPYELLDRDELAAVEPALAG-VRHklvgGLRLPND-ETGDCQLFTQRLAAMAEQLGVKFRFNtPVDGLLV 229

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495360896 232 VGESTIVTLENGDKIDADKVVIACGAWSRKLAATLGNIVPLETERGYNTTLP-------PEAFNL--TRQLyfndhgfVV 302
Cdd:PRK00711  230 EGGRITGVQTGGGVITADAYVVALGSYSTALLKPLGVDIPVYPLKGYSLTVPitdedraPVSTVLdeTYKI-------AI 302

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495360896 303 TPLSTGIRVGGAVELGGLELKPNFRRAEAMLKKAGRFLPGlkleGGRQ-----WMGFRPSMPDCLPVIGtarATPsviYA 377
Cdd:PRK00711  303 TRFDDRIRVGGMAEIVGFDLRLDPARRETLEMVVRDLFPG----GGDLsqatfWTGLRPMTPDGTPIVG---ATR---YK 372

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....
gi 2495360896 378 -----FGHGHLGLTQSAATARLVTQLASGEETAISVDPFRPGRF 416
Cdd:PRK00711  373 nlwlnTGHGTLGWTMACGSGQLLADLISGRKPAIDADDLSVARY 416
PRK12409 PRK12409
D-amino acid dehydrogenase small subunit; Provisional
 9-397 2.53e-28

D-amino acid dehydrogenase small subunit; Provisional


Pssm-ID: 237093 [Multi-domain]  Cd Length: 410  Bit Score: 115.12  E-value: 2.53e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495360896   9 VLVIGTGIIGSMAALYLQNAGREVVFLERGEVARGASS-GNAGILAFPEIIPIPAPGIMKKAPRWLFDPLGPLSVPPAYA 87
Cdd:PRK12409    4 IAVIGAGITGVTTAYALAQRGYQVTVFDRHRYAAMETSfANGGQLSASNAEVWNHWATVLKGLKWMLRKDAPLLLNPKPS 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495360896  88 -HKIApWLWRFWRasaerNFRHGLKSLADINRLAAMEMAHVAAMPELSHL---VSKTGTLDLYDSEASLNAARRDWDEKA 163
Cdd:PRK12409   84 wHKYS-WLAEFLA-----HIPNYRANTIETVRLAIAARKHLFDIAEREGIdfdLERRGILHIYHDKAGFDHAKRVNALLA 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495360896 164 SAGFSFERVGRSEIEALQPGLAPQFRHAMFSPDGlQVSDPYDFTRAIFDLVLARGASLRKG-EAERIDAVGESTIVTLEN 242
Cdd:PRK12409  158 EGGLERRAVTPEEMRAIEPTLTGEYYGGYYTPSD-STGDIHKFTTGLAAACARLGVQFRYGqEVTSIKTDGGGVVLTVQP 236

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495360896 243 GD-----KIDADKVVIACGAWSRKLAATLG---NIVPLeteRGYNTT--LPPEAfnlTRQL-----YFNDHGFVVTP-LS 306
Cdd:PRK12409  237 SAehpsrTLEFDGVVVCAGVGSRALAAMLGdrvNVYPV---KGYSITvnLDDEA---SRAAapwvsLLDDSAKIVTSrLG 310

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495360896 307 TG-IRVGGAVELGGLELKPNFRRAEAMLKKAGRFLPGLKLEGGRQWMGFRPSMPDCLPVIGTARAtPSVIYAFGHGHLGL 385
Cdd:PRK12409  311 ADrFRVAGTAEFNGYNRDIRADRIRPLVDWVRRNFPDVSTRRVVPWAGLRPMMPNMMPRVGRGRR-PGVFYNTGHGHLGW 389

                         410
                  ....*....|..
gi 2495360896 386 TQSAATARLVTQ 397
Cdd:PRK12409  390 TLSAATADLVAQ 401
LhgO COG0579
L-2-hydroxyglutarate oxidase LhgO [Carbohydrate transport and metabolism];
6-267 1.71e-13

L-2-hydroxyglutarate oxidase LhgO [Carbohydrate transport and metabolism];


Pssm-ID: 440344 [Multi-domain]  Cd Length: 418  Bit Score: 71.72  E-value: 1.71e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495360896   6 KCDVLVIGTGIIGSMAALYLQNA-GREVVFLERG-EVARGASSGNAGIL--AFpeiipIPAPGIMKkaprwlfdplgpls 81
Cdd:COG0579     4 MYDVVIIGAGIVGLALARELSRYeDLKVLVLEKEdDVAQESSGNNSGVIhaGL-----YYTPGSLK-------------- 64

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495360896  82 vpPAYAHKIAPWLWRFwraSAERNFRHglksladiNRLAAMEMAHVAAmpELSHLvsktgtLDLYdseaslnaarrdwdE 161
Cdd:COG0579    65 --ARLCVEGNELFYEL---CRELGIPF--------KRCGKLVVATGEE--EVAFL------EKLY--------------E 109

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495360896 162 KASA-GFS-FERVGRSEIEALQPGLAPQFRHAMFSPDGLQVsDPYDFTRAIFDLVLARGASLRKG-EAERIDAVGESTIV 238
Cdd:COG0579   110 RGKAnGVPgLEILDREELRELEPLLSDEGVAALYSPSTGIV-DPGALTRALAENAEANGVELLLNtEVTGIEREGDGWEV 188

                         250       260
                  ....*....|....*....|....*....
gi 2495360896 239 TLENGDkIDADKVVIACGAWSRKLAATLG 267
Cdd:COG0579   189 TTNGGT-IRARFVINAAGLYADRLAQMAG 216
mnmC PRK01747
bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent ...
 8-416 6.51e-09

bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC;


Pssm-ID: 234978 [Multi-domain]  Cd Length: 662  Bit Score: 57.93  E-value: 6.51e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495360896   8 DVLVIGTGIIGSMAALYLQNAGREVVFLER-GEVARGASSGNAGILafpeiipipAPGIMKKAPRwlfdpLGPLSvPPAY 86
Cdd:PRK01747  262 DAAIIGGGIAGAALALALARRGWQVTLYEAdEAPAQGASGNRQGAL---------YPLLSKDDNA-----LSRFF-RAAF 326

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495360896  87 AHKiapwlWRFWRA--SAERNFRH---GLKSLA----DINRLAAmeMAHVAAMPELSHLVSKtgtldlydSEASlnaarr 157
Cdd:PRK01747  327 LFA-----RRFYDAlpAAGVAFDHdwcGVLQLAwdekSAEKIAK--MLALGLPAELARALDA--------EEAE------ 385

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495360896 158 dwdekASAGFSFERVGrseiealqpglapqfrhaMFSPDGLQVSdPYDFTRAIFDLvLARGASLRKG-EAERIDAVGEST 236
Cdd:PRK01747  386 -----ELAGLPVPCGG------------------IFYPQGGWLC-PAELCRALLAL-AGQQLTIHFGhEVARLEREDDGW 440

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495360896 237 IVTLENGDKIDADKVVIACGAWSRKLAATLGniVPLETERGYNTTLPP-EAFNLTRQLYFNDhGFVVTPLSTGIRVGGAV 315
Cdd:PRK01747  441 QLDFAGGTLASAPVVVLANGHDAARFAQTAH--LPLYSVRGQVSHLPTtPALSALKQVLCYD-GYLTPQPANGTHCIGAS 517

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495360896 316 ELGGlELKPNFRRAE--AMLKKAGRFLPGLKL--------EGGRQwmGFRPSMPDCLPVIG-----------------TA 368
Cdd:PRK01747  518 YDRD-DTDTAFREADhqENLERLAECLPQALWakevdvsaLQGRV--GFRCASRDRLPMVGnvpdeaatlaeyaalanQQ 594

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2495360896 369 RATPSVIY-----AFGHGHLGLTQSAATARLVTQLASGE------ETAISVDpfrPGRF 416
Cdd:PRK01747  595 PARDAPRLpglyvAGALGSRGLCSAPLGAELLASQIEGEplplerDLLAALH---PNRF 650
solA PRK11259
N-methyl-L-tryptophan oxidase;
4-417 3.56e-08

N-methyl-L-tryptophan oxidase;


Pssm-ID: 236887 [Multi-domain]  Cd Length: 376  Bit Score: 54.84  E-value: 3.56e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495360896   4 TLKCDVLVIGTGIIGSMAALYLQNAGREVVFLERGEV--ARGASSGNAGI--LAFPEiipipapgimkkaprwlfdplGP 79
Cdd:PRK11259    1 TMRYDVIVIGLGSMGSAAGYYLARRGLRVLGLDRFMPphQQGSSHGDTRIirHAYGE---------------------GP 59

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495360896  80 LSVP---PAYAhkiapwLWRfwrasaernfrhglkslaDINRLAAmemahvaampelSHLVSKTGTLDL--YDSEASLNA 154
Cdd:PRK11259   60 AYVPlvlRAQE------LWR------------------ELERESG------------EPLFVRTGVLNLgpADSDFLANS 103

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495360896 155 AR--RDWD---EKASAgfsfervgrSEIEALQPGLAPQFRH-AMFSPDGlQVSDPYDFTRAIFDLVLARGASLRKGE-AE 227
Cdd:PRK11259  104 IRsaRQHGlphEVLDA---------AEIRRRFPQFRLPDGYiALFEPDG-GFLRPELAIKAHLRLAREAGAELLFNEpVT 173

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495360896 228 RIDAVGESTIVTLENGdKIDADKVVIACGAWSRKLAATLGniVPLETER------------GYNTTLPpeAFNLT----R 291
Cdd:PRK11259  174 AIEADGDGVTVTTADG-TYEAKKLVVSAGAWVKDLLPPLE--LPLTPVRqvlawfqadgrySEPNRFP--AFIWEvpdgD 248

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495360896 292 QLYfndhGFvvtPLSTGIRVGGAVELGGL------ELKP--NFRRAEAMLKKAGR-FLPGLKleggrqwmgfrPSM---- 358
Cdd:PRK11259  249 QYY----GF---PAENGPGLKIGKHNGGQeitspdERDRfvTVAEDGAELRPFLRnYLPGVG-----------PCLrgaa 310

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2495360896 359 ------PDCLPVIGTARATPSVIYAFG-HGHlGLTQSAATARLVTQLASGEETAISVDPFRPGRFS 417
Cdd:PRK11259  311 ctytntPDEHFIIDTLPGHPNVLVASGcSGH-GFKFASVLGEILADLAQDGTSDFDLSPFSLSRFA 375
soxA_mon TIGR01377
sarcosine oxidase, monomeric form; Sarcosine oxidase catalyzes the oxidative demethylation of ...
 8-417 2.40e-07

sarcosine oxidase, monomeric form; Sarcosine oxidase catalyzes the oxidative demethylation of sarcosine to glycine. The reaction converts tetrahydrofolate to 5,10-methylene-tetrahydrofolate. The enzyme is known in monomeric and heterotetrameric (alpha,beta,gamma,delta) forms [Energy metabolism, Amino acids and amines]


Pssm-ID: 130444 [Multi-domain]  Cd Length: 380  Bit Score: 52.52  E-value: 2.40e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495360896   8 DVLVIGTGIIGSMAALYLQNAGREVVFLERGEV--ARGASSGNAGIL--AFPEIIPIPapgIMKKAPRwlfdplgplsvp 83
Cdd:TIGR01377   2 DVIVVGAGIMGCFAAYHLAKHGKKTLLLEQFDLphSRGSSHGQSRIIrkAYPEDFYTP---MMLECYQ------------ 66

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495360896  84 payahkiapwLWrfwrASAERNFRHGLKSLADinrLAAMEMAHVAAMPELSHLVSKTGTL-DLYDSEAslnaarrdwdek 162
Cdd:TIGR01377  67 ----------LW----AQLEKEAGTKLHRQTG---LLLLGPKENQFLKTIQATLSRHGLEhELLSSKQ------------ 117

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495360896 163 ASAGFSFERVGRSEIealqpglapqfrhAMFSPDGlQVSDPYDFTRAIFDLVLARGASLRKGEAERIDAVGESTIVTLEN 242
Cdd:TIGR01377 118 LKQRFPNIRVPRNEV-------------GLLDPNG-GVLYAEKALRALQELAEAHGATVRDGTKVVEIEPTELLVTVKTT 183

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495360896 243 GDKIDADKVVIACGAWSRKLAATLGNIVPLETER---GYNTTLPPEAFNLTrQLYFNDHGFVVTPLSTGIRVGGAVEL-- 317
Cdd:TIGR01377 184 KGSYQANKLVVTAGAWTSKLLSPLGIEIPLQPLRinvCYWREKEPGSYGVS-QAFPCFLVLGLNPHIYGLPSFEYPGLmk 262

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495360896 318 ----GGLELKPNFR--------RAEAMLKKAGR-FLPGLKLEGGRQWMGFRPSMPDCLPVIGTARATPSVIYAFG-HGHl 383
Cdd:TIGR01377 263 vyyhHGQQIDPDERdcpfgadiEDVQILRKFVRdHLPGLNGEPKKGEVCMYTNTPDEHFVIDLHPKYDNVVIGAGfSGH- 341

                         410       420       430
                  ....*....|....*....|....*....|....
gi 2495360896 384 GLTQSAATARLVTQLASGEETAISVDPFRPGRFS 417
Cdd:TIGR01377 342 GFKLAPVVGKILAELAMKLKPSYDLAIFSLNRFA 375
SdhA COG1053
Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [Energy production and ...
 4-55 1.96e-05

Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [Energy production and conversion]; Succinate dehydrogenase/fumarate reductase, flavoprotein subunit is part of the Pathway/BioSystem: TCA cycle


Pssm-ID: 440673 [Multi-domain]  Cd Length: 443  Bit Score: 46.75  E-value: 1.96e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2495360896   4 TLKCDVLVIGTGIIGSMAALYLQNAGREVVFLERGEVARGASSGNAGILAFP 55
Cdd:COG1053     1 DHEYDVVVVGSGGAGLRAALEAAEAGLKVLVLEKVPPRGGHTAAAQGGINAA 52
COG1233 COG1233
Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and ...
 8-271 1.78e-04

Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440846 [Multi-domain]  Cd Length: 491  Bit Score: 43.68  E-value: 1.78e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495360896   8 DVLVIGTGIIGSMAALYLQNAGREVVFLERGEVARGASSG--------NAGilafPEIIPipapgiMKKAPRWLFDPLGP 79
Cdd:COG1233     5 DVVVIGAGIGGLAAAALLARAGYRVTVLEKNDTPGGRARTferpgfrfDVG----PSVLT------MPGVLERLFRELGL 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495360896  80 ------LSVPPAYAH----------------------KIAP---WLWRFWRASAERNFRHGLKSLADINRLAAMEMAHVA 128
Cdd:COG1233    75 edylelVPLDPAYRVpfpdgraldlprdlertaaeleRLFPgdaEAYRRFLAELRRLYDALLEDLLYRPLLSLRDLLRPL 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495360896 129 AMPELSHLVSKTGTlDLYDSEASlnaarrdwDEKASAGFSFervgrseiEALQPGLAP-------------QFRHAMFSP 195
Cdd:COG1233   155 ALARLLRLLLRSLR-DLLRRYFK--------DPRLRALLAG--------QALYLGLSPdrtpalyaliaylEYAGGVWYP 217

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2495360896 196 D-GLQVsdpydFTRAIFDLVLARGASLRKG-EAERIDAV-GESTIVTLENGDKIDADKVVIACGAWsrklaATLGNIVP 271
Cdd:COG1233   218 KgGMGA-----LADALARLAEELGGEIRTGaEVERILVEgGRATGVRLADGEEIRADAVVSNADPA-----HTYLRLLG 286
PRK12842 PRK12842
putative succinate dehydrogenase; Reviewed
 1-55 3.73e-04

putative succinate dehydrogenase; Reviewed


Pssm-ID: 237224 [Multi-domain]  Cd Length: 574  Bit Score: 42.76  E-value: 3.73e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2495360896   1 MTKTLKCDVLVIGTGIIGSMAALYLQNAGREVVFLERGEVARGASSGNAGILAFP 55
Cdd:PRK12842    4 MTNELTCDVLVIGSGAGGLSAAITARKLGLDVVVLEKEPVFGGTTAFSGGVLWIP 58
FadH2 COG0446
NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase ...
 182-263 4.00e-04

NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase [Lipid transport and metabolism];


Pssm-ID: 440215 [Multi-domain]  Cd Length: 322  Bit Score: 42.11  E-value: 4.00e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495360896 182 PGLAPQFRHAMFSPDGLQVSDPYDFTRaifdlvlaRGASLR-KGEAERIDAvgESTIVTLENGDKIDADKVVIACGAWSR 260
Cdd:COG0446    22 CGLPYYVGGGIKDPEDLLVRTPESFER--------KGIDVRtGTEVTAIDP--EAKTVTLRDGETLSYDKLVLATGARPR 91


                  ...
gi 2495360896 261 KLA 263
Cdd:COG0446    92 PPP 94
PRK13800 PRK13800
fumarate reductase/succinate dehydrogenase flavoprotein subunit;
5-40 8.09e-04

fumarate reductase/succinate dehydrogenase flavoprotein subunit;


Pssm-ID: 237512 [Multi-domain]  Cd Length: 897  Bit Score: 41.76  E-value: 8.09e-04
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 2495360896   5 LKCDVLVIGTGIIGSMAALYLQNAGREVVFLERGEV 40
Cdd:PRK13800   12 LDCDVLVIGGGTAGTMAALTAAEHGANVLLLEKAHV 47
ApbA pfam02558
Ketopantoate reductase PanE/ApbA; This is a family of 2-dehydropantoate 2-reductases also ...
 9-39 9.97e-04

Ketopantoate reductase PanE/ApbA; This is a family of 2-dehydropantoate 2-reductases also known as ketopantoate reductases, EC:1.1.1.169. The reaction catalyzed by this enzyme is: (R)-pantoate + NADP(+) <=> 2-dehydropantoate + NADPH. AbpA catalyzes the NADPH reduction of ketopantoic acid to pantoic acid in the alternative pyrimidine biosynthetic (APB) pathway. ApbA and PanE are allelic. ApbA, the ketopantoate reductase enzyme is required for the synthesis of thiamine via the APB biosynthetic pathway.


Pssm-ID: 426831 [Multi-domain]  Cd Length: 147  Bit Score: 39.14  E-value: 9.97e-04
                          10        20        30
                  ....*....|....*....|....*....|.
gi 2495360896   9 VLVIGTGIIGSMAALYLQNAGREVVFLERGE 39
Cdd:pfam02558   1 IAILGAGAIGSLLGARLAKAGHDVTLILRGA 31
FAD_binding_2 pfam00890
FAD binding domain; This family includes members that bind FAD. This family includes the ...
 8-56 9.99e-04

FAD binding domain; This family includes members that bind FAD. This family includes the flavoprotein subunits from succinate and fumarate dehydrogenase, aspartate oxidase and the alpha subunit of adenylylsulphate reductase.


Pssm-ID: 395718 [Multi-domain]  Cd Length: 398  Bit Score: 41.12  E-value: 9.99e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2495360896   8 DVLVIGTGIIGSMAALYLQNAGREVVFLERGEVARGA---SSGNAGILAFPE 56
Cdd:pfam00890   1 DVLVIGGGLAGLAAALAAAEAGLKVAVVEKGQPFGGAtawSSGGIDALGNPP 52
PRK05329 PRK05329
glycerol-3-phosphate dehydrogenase subunit GlpB;
6-53 2.07e-03

glycerol-3-phosphate dehydrogenase subunit GlpB;


Pssm-ID: 235412  Cd Length: 422  Bit Score: 40.22  E-value: 2.07e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 2495360896   6 KCDVLVIGTGIIGSMAALYLQNAGREVVFLERGEVARGASSGNAGILA 53
Cdd:PRK05329    2 KFDVLVIGGGLAGLTAALAAAEAGKRVALVAKGQGALHFSSGSIDLLG 49
PRK08275 PRK08275
putative oxidoreductase; Provisional
 2-45 2.25e-03

putative oxidoreductase; Provisional


Pssm-ID: 181346 [Multi-domain]  Cd Length: 554  Bit Score: 40.04  E-value: 2.25e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 2495360896   2 TKTLKCDVLVIGTGIIGSMAAL--YLQNAGREVVFLERGEVARGAS 45
Cdd:PRK08275    5 TQEVETDILVIGGGTAGPMAAIkaKERNPALRVLLLEKANVKRSGA 50
PRK09198 PRK09198
putative nicotinate phosphoribosyltransferase; Provisional
 128-221 2.60e-03

putative nicotinate phosphoribosyltransferase; Provisional


Pssm-ID: 236407 [Multi-domain]  Cd Length: 463  Bit Score: 39.88  E-value: 2.60e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495360896 128 AAMPELSHLVSKTGTldlyDSEASLNAARRDWDEKAsAGFSFERVGRSEIEAL-QPGLAPQFRHAM--FSPDGLQ--VSD 202
Cdd:PRK09198  189 AALGGAAHLVSFLGT----DTIPALLYAERYYNADM-AGFSIPATEHSVMTSWgREGELEAYRNMIeqFYPGGIVsiVSD 263

                          90       100
                  ....*....|....*....|....*..
gi 2495360896 203 PYDFTRAI--------FDLVLARGASL 221
Cdd:PRK09198  264 SYDLWNAItepwggelKDEILARGGTL 290
NAD_binding_9 pfam13454
FAD-NAD(P)-binding;
202-256 2.89e-03

FAD-NAD(P)-binding;


Pssm-ID: 433222 [Multi-domain]  Cd Length: 155  Bit Score: 38.03  E-value: 2.89e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2495360896 202 DPYDF-TRAIF--------DLVLARGA-----SLRKGEAERIDAVGESTIVTLENGDKIDADKVVIACG 256
Cdd:pfam13454  85 DPDDFpPRALYgrylrdrfEEALARAPagvtvRVHRARVTDLRPRGDGYRVLLADGRTLAADAVVLATG 153
NadB COG0029
Aspartate oxidase [Coenzyme transport and metabolism]; Aspartate oxidase is part of the ...
 3-45 3.39e-03

Aspartate oxidase [Coenzyme transport and metabolism]; Aspartate oxidase is part of the Pathway/BioSystem: NAD biosynthesis


Pssm-ID: 439800 [Multi-domain]  Cd Length: 521  Bit Score: 39.70  E-value: 3.39e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 2495360896   3 KTLKCDVLVIGTGIIGSMAALYLQNAGReVVFLERGEVARGAS 45
Cdd:COG0029     1 ERLKTDVLVIGSGIAGLSAALKLAERGR-VTLLTKGELGESNT 42
PRK10015 PRK10015
oxidoreductase; Provisional
 6-70 3.41e-03

oxidoreductase; Provisional


Pssm-ID: 182194 [Multi-domain]  Cd Length: 429  Bit Score: 39.57  E-value: 3.41e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2495360896   6 KCDVLVIGTGIIGSMAALYLQNAGREVVFLERGEVArGASSGNAGILaFPEIIPIPAPGIMKKAP 70
Cdd:PRK10015    5 KFDAIVVGAGVAGSVAALVMARAGLDVLVIERGDSA-GCKNMTGGRL-YAHTLEAIIPGFAASAP 67
PBEF_like cd01569
pre-B-cell colony-enhancing factor (PBEF)-like. The mammalian members of this group of ...
 128-221 4.37e-03

pre-B-cell colony-enhancing factor (PBEF)-like. The mammalian members of this group of nicotinate phosphoribosyltransferases (NAPRTases) were originally identified as genes whose expression is upregulated upon activation in lymphoid cells. In general, nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting, reaction in the NAD salvage synthesis.


Pssm-ID: 238803 [Multi-domain]  Cd Length: 407  Bit Score: 39.18  E-value: 4.37e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495360896 128 AAMPELSHLVSKTGTldlyDSEASLNAARRDWDEKASAGFSFERVGRS---------EIEALQpGLAPQFRHAMFSpdgl 198
Cdd:cd01569   187 AALGGAAHLVNFKGT----DTIPALDAAYAYYYEDPMAGFSIPAAEHStmtawgrerELEAFR-NLLEQFGPGIVS---- 257

                          90       100       110
                  ....*....|....*....|....*....|
gi 2495360896 199 QVSDPYDFTRAIF-------DLVLARGASL 221
Cdd:cd01569   258 VVSDSYDFWNALTlwgprlkDEILARGGTL 287
PRK12843 PRK12843
FAD-dependent oxidoreductase;
8-55 4.97e-03

FAD-dependent oxidoreductase;


Pssm-ID: 237225 [Multi-domain]  Cd Length: 578  Bit Score: 38.95  E-value: 4.97e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 2495360896   8 DVLVIGTGIIGSMAALYLQNAGREVVFLERGEVARGASSGNAGILAFP 55
Cdd:PRK12843   18 DVIVIGAGAAGMSAALFAAIAGLKVLLVERTEYVGGTTATSAGTTWIP 65
PRK07121 PRK07121
FAD-binding protein;
7-51 5.93e-03

FAD-binding protein;


Pssm-ID: 180854 [Multi-domain]  Cd Length: 492  Bit Score: 38.71  E-value: 5.93e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 2495360896   7 CDVLVIGTGIIGSMAALYLQNAGREVVFLERGEVARGASSGNAGI 51
Cdd:PRK07121   21 ADVVVVGFGAAGACAAIEAAAAGARVLVLERAAGAGGATALSGGV 65
PanE COG1893
Ketopantoate reductase [Coenzyme transport and metabolism]; Ketopantoate reductase is part of ...
 9-42 7.37e-03

Ketopantoate reductase [Coenzyme transport and metabolism]; Ketopantoate reductase is part of the Pathway/BioSystem: Pantothenate/CoA biosynthesis


Pssm-ID: 441497 [Multi-domain]  Cd Length: 305  Bit Score: 38.30  E-value: 7.37e-03
                          10        20        30
                  ....*....|....*....|....*....|....
gi 2495360896   9 VLVIGTGIIGSMAALYLQNAGREVVFLERGEVAR 42
Cdd:COG1893     3 IAILGAGAIGGLLGARLARAGHDVTLVARGAHAE 36
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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