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Conserved domains on  [gi|2495644662|ref|WP_279902363|]
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MULTISPECIES: TonB-dependent receptor domain-containing protein [unclassified Pseudomonas]

Protein Classification

TonB-dependent receptor family protein( domain architecture ID 11469151)

TonB-dependent receptor family protein such as Escherichia coli Fe(3+) dicitrate transport protein FecA which is the outer membrane receptor protein in the Fe(3+) dicitrate transport system

Gene Ontology:  GO:0038023|GO:0009279|GO:0015343|GO:0015891
PubMed:  12948487
TCDB:  1.B.14

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
FecA COG4772
Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];
32-715 4.67e-134

Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];


:

Pssm-ID: 443804 [Multi-domain]  Cd Length: 681  Bit Score: 410.86  E-value: 4.67e-134
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662  32 AGQGASAAEPASEKEQRLETVVVRGEQKTEAQkakvkLEEVAGGTSLVDNAEVEKGRSSTLEDVLAFQPGV-IAQAAGGN 110
Cdd:COG4772     6 AAALLLAAAAAAEAATTLETVVVTGSRAAEAR-----LKDVPGSVSVVDREELENQAATSLREVLRRVPGVnVQEEDGFG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 111 DAIKISIRGSGANASPGyfregTKFLFDGLALTGP---GGTPYELLEMSGVNYTEVLRGANAFDYTALSLGGAINMVTHT 187
Cdd:COG4772    81 LRPNIGIRGLGPRRSRG-----ITLLEDGIPIAPApygDPAAYYFPDLERMERIEVLRGAAALRYGPQTVGGAINFVTRT 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 188 GHSSPGNYARFEAGSFGWRKQQLSTGGVVDDADYYISLSNSEREGYQDYTFNKAKGVVSNFGYRFSPKLDTRLIVRYREQ 267
Cdd:COG4772   156 IPTAFGGELRVTGGSFGYRRTHASVGGTVGNFGYLVEYSRKRGDGFRDNSGFDINDFNAKLGYRLSDRQELTLKFQYYDE 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 268 YHENASTLTRAQLKDDPSQPNPTTVAQRGDSTKngsiwVGSKTTYTLDDDSQVELGLVYHN------YRQILGKKSP--- 338
Cdd:COG4772   236 DANTPGGLTDAQFDADPRQSYRPADQFDTRRTQ-----LSLRYEHQLSDNTTLTTTAYYNDfsrnwyIRQNTADPNTpgl 310

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 339 -VIPNHWQWRDLNSSLRYLRSDRLFGLQSNTTLSF---SNTLHDRAEVKTYDGVSRKLLKETNYSGSFDTV-FAAGNELE 413
Cdd:COG4772   311 gLRGNPRGYRSYGIEPRLTHRFELGGVPHTLEVGLryhREEEDRKQYVNTYGQGRSGAGLRRDRRFSADALaAYAQNRFE 390

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 414 LTERLWLSSGLSLVNIRRDVDVNFSDRANTSPYPQHyKYDNWSlaPRLGLRYFLTPDIQLFGNVSRSIDPPSAWSISPSG 493
Cdd:COG4772   391 LTGRLTLTPGLRYEHIRRDRTDRYSTRTGGDDSGSN-SYSEFL--PGLGLLYQLTDNLQLYANVSRGFEPPTFGDLAYGN 467

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 494 PTNNyakTLVEQKGNTVEIGIRGARGP-LSGSLALYRSWLHDELLNVEIipargNSPAVTSTSNASATIHQGVEAGLDAE 572
Cdd:COG4772   468 GGNP---DLKPEKSWNYELGTRGRIGNgLSAEVALFYIDYDNELGSCSA-----AGGDRSTFTNAGETRHQGLELALDYD 539

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 573 LWRGvRGDTLVLRQAYTFNDFYYRN--DDEFGANELPGLPRHIYQAELKYQHaSGFYAGVDVRTASSTPVDYANSFQ--- 647
Cdd:COG4772   540 LLKG-GGLGLPLFAAYTYTDAEFTSdfGPVFAGNRLPYVPRHQLTAGLGYEH-GGWTANLNGRYVSEQFTDAANTVAdgs 617

                         650       660       670       680       690       700       710
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2495644662 648 ---APSYTVFGAKLGYeEPGQRWQVFLDLRNLTDEHYATTISPIYnargndAAALYSGDGFGAFTGVALRF 715
Cdd:COG4772   618 fgkIPSYTVLDLSASY-DFGKNLSLFAGVNNLFDKRYIASRAPNY------AAGIRPGPPRTVYAGLRLKF 681
 
Name Accession Description Interval E-value
FecA COG4772
Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];
32-715 4.67e-134

Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];


Pssm-ID: 443804 [Multi-domain]  Cd Length: 681  Bit Score: 410.86  E-value: 4.67e-134
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662  32 AGQGASAAEPASEKEQRLETVVVRGEQKTEAQkakvkLEEVAGGTSLVDNAEVEKGRSSTLEDVLAFQPGV-IAQAAGGN 110
Cdd:COG4772     6 AAALLLAAAAAAEAATTLETVVVTGSRAAEAR-----LKDVPGSVSVVDREELENQAATSLREVLRRVPGVnVQEEDGFG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 111 DAIKISIRGSGANASPGyfregTKFLFDGLALTGP---GGTPYELLEMSGVNYTEVLRGANAFDYTALSLGGAINMVTHT 187
Cdd:COG4772    81 LRPNIGIRGLGPRRSRG-----ITLLEDGIPIAPApygDPAAYYFPDLERMERIEVLRGAAALRYGPQTVGGAINFVTRT 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 188 GHSSPGNYARFEAGSFGWRKQQLSTGGVVDDADYYISLSNSEREGYQDYTFNKAKGVVSNFGYRFSPKLDTRLIVRYREQ 267
Cdd:COG4772   156 IPTAFGGELRVTGGSFGYRRTHASVGGTVGNFGYLVEYSRKRGDGFRDNSGFDINDFNAKLGYRLSDRQELTLKFQYYDE 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 268 YHENASTLTRAQLKDDPSQPNPTTVAQRGDSTKngsiwVGSKTTYTLDDDSQVELGLVYHN------YRQILGKKSP--- 338
Cdd:COG4772   236 DANTPGGLTDAQFDADPRQSYRPADQFDTRRTQ-----LSLRYEHQLSDNTTLTTTAYYNDfsrnwyIRQNTADPNTpgl 310

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 339 -VIPNHWQWRDLNSSLRYLRSDRLFGLQSNTTLSF---SNTLHDRAEVKTYDGVSRKLLKETNYSGSFDTV-FAAGNELE 413
Cdd:COG4772   311 gLRGNPRGYRSYGIEPRLTHRFELGGVPHTLEVGLryhREEEDRKQYVNTYGQGRSGAGLRRDRRFSADALaAYAQNRFE 390

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 414 LTERLWLSSGLSLVNIRRDVDVNFSDRANTSPYPQHyKYDNWSlaPRLGLRYFLTPDIQLFGNVSRSIDPPSAWSISPSG 493
Cdd:COG4772   391 LTGRLTLTPGLRYEHIRRDRTDRYSTRTGGDDSGSN-SYSEFL--PGLGLLYQLTDNLQLYANVSRGFEPPTFGDLAYGN 467

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 494 PTNNyakTLVEQKGNTVEIGIRGARGP-LSGSLALYRSWLHDELLNVEIipargNSPAVTSTSNASATIHQGVEAGLDAE 572
Cdd:COG4772   468 GGNP---DLKPEKSWNYELGTRGRIGNgLSAEVALFYIDYDNELGSCSA-----AGGDRSTFTNAGETRHQGLELALDYD 539

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 573 LWRGvRGDTLVLRQAYTFNDFYYRN--DDEFGANELPGLPRHIYQAELKYQHaSGFYAGVDVRTASSTPVDYANSFQ--- 647
Cdd:COG4772   540 LLKG-GGLGLPLFAAYTYTDAEFTSdfGPVFAGNRLPYVPRHQLTAGLGYEH-GGWTANLNGRYVSEQFTDAANTVAdgs 617

                         650       660       670       680       690       700       710
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2495644662 648 ---APSYTVFGAKLGYeEPGQRWQVFLDLRNLTDEHYATTISPIYnargndAAALYSGDGFGAFTGVALRF 715
Cdd:COG4772   618 fgkIPSYTVLDLSASY-DFGKNLSLFAGVNNLFDKRYIASRAPNY------AAGIRPGPPRTVYAGLRLKF 681
ligand_gated_channel cd01347
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ...
 75-715 9.33e-42

TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.


Pssm-ID: 238657 [Multi-domain]  Cd Length: 635  Bit Score: 161.47  E-value: 9.33e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662  75 GTSLVDNAEVEKGRSSTLEDVLAFQPGVIAQAAGGNDAIKISIRGSGANaspgyfreGTKFLFDGLALTGPGGT------ 148
Cdd:cd01347     1 SVSVITAEDIEKQPATSLADLLRRIPGVSVTRGGGGGGSTISIRGFGPD--------RTLVLVDGLPLASSNYGrgvdln 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 149 --PYELLEmsGVnytEVLRGANAFDYTALSLGGAINMVT------HTGHSSPGNYARFEAGSFGWRKQQLSTGGVVDDAD 220
Cdd:cd01347    73 tiPPELIE--RV---EVLKGPSSALYGSGAIGGVVNIITkrptdeFGGSVTAGYGSDNSGSSGGGGFDVSGALADDGAFG 147

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 221 YYISLSNSEREGYQ------DYTFNKAKGVVSNFGYRFSPKLDTRLIVRY-REQYHENASTL-TRAQLKDDPSQPNPTTV 292
Cdd:cd01347   148 ARLYGAYRDGDGTIdgdgqaDDSDEERYNVAGKLDWRPDDDTRLTLDAGYqDQDADGPGGTLpANGTGSSLGGGPSSNTN 227

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 293 AQRGDSTKNGSIWVGSKT-TYTLDDDS-QVELGLVYHNYRQilgKKSPVIPNHWQWRDLNSSLRYLRSDRL----FGLQS 366
Cdd:cd01347   228 GDRDWDYRDRYRKRASLGlEHDLNDTGwTLRANLSYSYTDN---DGDPLILNGGNNAAGGDLGRSGYSSERdttqLGFDA 304

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 367 NTTLSFsNTLHDRAEVKTYDGVSRKLLKETNYSgsfdtVFAAGNeLELTERLWLSSGLslvniRRD-VDVNFSDRANTSP 445
Cdd:cd01347   305 GLNAPF-GTGPVAHTLTLGVEYRREELDEKQTA-----LYAQDT-IELTDDLTLTLGL-----RYDhYDQDSKDTIAGGT 372

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 446 YPQhYKYDNWSlaPRLGLRYFLTPDIQLFGNVSRSIDPPSAWSISPSG---PTNNYAKTLVE-QKGNTVEIGIRGARGP- 520
Cdd:cd01347   373 TAK-KSYSHWS--PSLGLVYKLTDGLSLYASYSQGFRAPSLGELYGGGshgGTAAVGNPNLKpEKSKQYELGLKYDPGDg 449

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 521 LSGSLALYRSWLHDELLNVeiiPARGNSPAVTSTSNASATIHQGVEAGLDAELWRGVRGDTlvlrqAYTFNDFYY-RNDD 599
Cdd:cd01347   450 LTLSAALFRIDIKNEIVST---PTNTGLGLVTVYVNGGKARIRGVELEASYDLTDGLGLTG-----SYTYTDTEVkRTDG 521

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 600 EFGANELPGLPRHIYQAELKYQH-ASGFYAGVDVRTASSTPVDYA---NSFQAPSYTVFGAKLGYeEPGQRWQVFLDLRN 675
Cdd:cd01347   522 ATTGNRLPGIPKHTANLGLDYELpDEGLTAGGGVRYRGKQYADTAngnNTVKVPGYTLVDLSASY-QFTKNLTLRLGVNN 600

                         650       660       670       680
                  ....*....|....*....|....*....|....*....|
gi 2495644662 676 LTDEHYATTISPIYNargndAAALYSGDGFGAFTGVALRF 715
Cdd:cd01347   601 LFDKDYYTSLSVRGS-----GLYGYYGPGRTYYLSVSYKF 635
TonB_dep_Rec pfam00593
TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
 246-714 3.08e-35

TonB dependent receptor; This model now only covers the conserved part of the barrel structure.


Pssm-ID: 395474 [Multi-domain]  Cd Length: 475  Bit Score: 139.91  E-value: 3.08e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 246 SNFGYRFSPKLDTRLIVRYREQYHENASTLTRAQLKDDPSQPNPTTVAQRGDSTKNGSIWVGSKTTYTLDDD----SQVE 321
Cdd:pfam00593   3 QLSLDLLGDDTLLTLGYDYSRYTDGLDLGLTLDGYGNDGGYLGDRPLYYGRDYSDTDRKRLSLGYDYDLGDGlswlSTLR 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 322 LGLVYHNYRQILGKKSPVIPNHWQWRDLNSSLRYLRSDRLFGLQSNTTLSFSNTLHDRAEVKTYDGVSRKLLKETNYSGS 401
Cdd:pfam00593  83 LGLRYSSLDGDYTSNSSGLSGAGDYLSDDRLYGLYGLDGDLELSLDLSHDLLLGVELRTAGLDYRRLDDDAYDPYDPANP 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 402 FDTVFA----------AGNELELTERLWLSSGLSLVNIRRDVDVNFSDRANTSpypqhYKYDNWSlaPRLGLRYFLTPDI 471
Cdd:pfam00593 163 SSSSYSdtttdsyglyLQDNIKLTDRLTLTLGLRYDHYSTDGDDGNGGGDNFS-----RSYSAFS--PRLGLVYKPTDNL 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 472 QLFGNVSRSIDPPSAWSISPSGPTNNYA------KTLVEQKGNTVEIGIRGARGPLSGSLALYRSWLHDELLNVEIIPar 545
Cdd:pfam00593 236 SLYASYSRGFRAPSLGELYGSGSGGGGGavaggnPDLKPETSDNYELGLKYDDGRLSLSLALFYIDIKNLITSDPDGP-- 313

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 546 GNSPAVTSTSNASATIHQGVEAGLDAELWRgvrgdTLVLRQAYTFNDFYYRNDDEFGANELPGLPRHIYQAELKYQHASG 625
Cdd:pfam00593 314 GLGGTVYTYTNVGKARIRGVELELSGRLWG-----LGLSGGGYTYTDADDDADADDTGNPLPNVPRHTANLGLTYDFPLG 388

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 626 -FYAGVDVR---TASSTPVDYANSFQAPSYTVFGAKLGYeEPGQRWQVFLDLRNLTDEHYATtispiYNARGNDAAALYS 701
Cdd:pfam00593 389 gWGARLGARyvgSGERRYGDAANTFKTPGYTLVDLSAGY-RLNKNLTLRLGVNNLFDKYYKR-----YYSSGGGNLGGYP 462

                         490
                  ....*....|...
gi 2495644662 702 GDGFGAFTGVALR 714
Cdd:pfam00593 463 GPGRTFYLGLSYK 475
TonB-siderophor TIGR01783
TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of ...
 71-701 2.42e-22

TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of TonB-dependent outer membrane siderophore receptors. It has no overlap with TonB receptors known to transport other substances, but is likely incomplete due to lack of characterizations. It is likely that genuine siderophore receptors will be identified which score below the noise cutoff to this model at which point the model should be updated. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273805 [Multi-domain]  Cd Length: 651  Bit Score: 102.11  E-value: 2.42e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662  71 EVAGGTSLVDNAEVEKGRSSTLEDVLAFQPGVIAQAAGG-NDAIKISIRGSGANASPGYFRegtkflFDGLALTGPGGtp 149
Cdd:TIGR01783   1 DIPQSVSVITRQELEDQQAGSLSEALQRVPGVVVGGSGGtTQFGNITIRGFGLEVDIDNVY------LDGVPLLSRGN-- 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 150 YELLEMSGVNYTEVLRGANAFDYTALSLGGAINMVTHTGHSSPGNYARFEAGSFgwrkqqlstGGVVDDADYYISLSNSE 229
Cdd:TIGR01783  73 LAIVDPAMVERVEVLRGPASLLYGGSAPGGVINIVTKRPQDEPKGSVTFGAGTR---------SGYRTAFDLGGPLGADG 143

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 230 regyqdytfnkakgvvsNFGYRFSPkldtrlIVRYREQYHENASTLTRAQlkddpsqpNPTTVAQRGDSTKNGSIWvgsk 309
Cdd:TIGR01783 144 -----------------TFRGRLNG------ARQDGDSFYDGAGEETRLG--------ATATDWQLDDRTLLRLGA---- 188

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 310 tTYTLDDDSQVELGLVYHNYRQILGKKSPVIPNHWQWRDLNS--SLRY-LRSDRLFGL--QSNTTLSFSNTLHDRAEVK- 383
Cdd:TIGR01783 189 -YYQKERDRGGYGGLPASGGTSGRDLSSDRYLGTSSNRNYDDreYLSYgLSLEYQFNDvwTGKQNLRYSYFDTDSNQVQa 267

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 384 --------------TYDGVSRKLLK-ETNYSGSFDT------VFAAGNELELTERLWLSSGLSLVNI---------RRDV 433
Cdd:TIGR01783 268 sgyssdgglfgrslTVVNVKQDRVQiDAGLDGEFETgpiehdLLLGVSYGQRTTNRFNNTGYPSDNIysltatssaRTDI 347

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 434 DVNFSDRANTSPYPQHYKY--------DNWSLA-----------------------------PRLGLRYFLTPDIQLFGN 476
Cdd:TIGR01783 348 GDSPKDRALSSTTKALNGValqrillaDKWTLTlggrydsvdvksnngvagstgkrddsqftPSLGVAYKPTDDWSLYAS 427

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 477 VSRSIDPPsawSISPSGPTNNyAKTLVEQKGNTVEIGIRGARG-PLSGSLALYRSWLHDELLNveiipargNSPAVTSTS 555
Cdd:TIGR01783 428 YAESFKPG---GYYPKGAGNS-GDILEPEKGKNYELGVRYDLGdSLLATAALFRITKDNQLVQ--------DPVNGTFSV 495

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 556 NASATIHQGVEAGLDAELWRGVRgdtLVLRQAYTFNDFYYRNDDEFGANELPGLPRHIYQAELKYQ-----HASGFYAGV 630
Cdd:TIGR01783 496 NAGKTRNRGVELEARGYLTPGLS---LSAGYTYTDAEFTEDTNGDTQGNTVPFVPKHTASLWASYAppvgdNGLTLGGGV 572

                         650       660       670       680       690       700       710
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2495644662 631 dVRTASSTPVDyANSFQAPSYTVFGAKLGYE-EPGQRWQVFLDLRNLTDEHYATTispiYNARGNDAAALYS 701
Cdd:TIGR01783 573 -QYTGKAYVDG-GNTGKVPSYTVVDLSVRYDlTKKKNLTLALNVNNLFDRDYYTS----GYRWGPSAYIYPG 638
PRK13483 PRK13483
ligand-gated channel protein;
24-652 9.18e-12

ligand-gated channel protein;


Pssm-ID: 184080 [Multi-domain]  Cd Length: 660  Bit Score: 68.26  E-value: 9.18e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662  24 GIGSLMMAAGQGASAAEPASEKEQRLETVVVrgeqkTEAQKAKVkLEEVAGGTSLVDNAEVEKGRSSTLEDVLAFQPGVI 103
Cdd:PRK13483    8 VISALCLLPAVFVTHALAQAAPDKTMETVVV-----TASGYEQQ-IRDAPASISVITREDLENRFYRDLTDALLDVPGVV 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 104 AqaAGGNDAIKISIRGSGANaspgYfregTKFLFDGLALT---------GPGGTPYELLEMSGVNYTEVLRGANAFDYTA 174
Cdd:PRK13483   82 V--TGGGDRTDISLRGMGSQ----Y----TLILVDGKRQSsretrpnsdGPGVEQAWTPPLAAIERIEVIRGPMSSLYGS 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 175 LSLGGAINMVTH-TGHSSPGNyARFEAgsfgwRKQQLSTGGVVDDADYYISLS-NSEREG---YQDYTFNKAKGVVSNFG 249
Cdd:PRK13483  152 DAIGGVINIITRkVPNEWQGE-VRLDT-----TLQENSDSGNVYQANFFVNGPlIKDLLGlqlYGQYTQREEDDIEGGYR 225

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 250 YRFSPKLDTRLIVRYREQYHENASTLTRAQLKD-------DPSQPNPTTVAQRGDSTkngsiwvgSKTTYtldDDSQVEL 322
Cdd:PRK13483  226 DKDARSLTAKLALTPNEDHDIMLEVGTSNQERDstvgktvAPLAPGESCGRRGCPES--------STTEY---ERSTVSL 294

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 323 GlvyHNYRqilgkkspvipnhWQWRDLNSSLRY----------------LRSDRLFGLQSNTTLSF-SNTLHDRAEVKTy 385
Cdd:PRK13483  295 S---HTGR-------------WDFGTSDTYIQHeefdnksremkikntdFQSSLVAPLGQEHTLTFgAAYNHQDLTDET- 357

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 386 dgvSRKLLKETNYSGSFDTVFAAgNELELTERLWLSSGLslvniRRDVDVNFSdrantspypQHYK---YDNWSLAPRLG 462
Cdd:PRK13483  358 ---SNQISDLTDISRTQWAVFSE-DEWRIADDFALTGGL-----RLDHDENFG---------GHVSprvYGVWNLAPSWT 419

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 463 LRyfltpdiqlfGNVSRSIDPPSAWSISP-----SGPTNNYAK-TLVEQKGNTVEIGIRGARGP-LSGSLALYRSWLHDE 535
Cdd:PRK13483  420 VK----------GGVSTGFRAPSLRQTTPdwgqvSRGGNIYGNpDLKPETSLNKELGLYYDLGSgLTASLTVFYNEFKDK 489

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 536 LLNVEiIPAR---------GNSPavTSTSNASATIHQGVEAGLDAELWRgvrgdTLVLRQAYTFNDFYYRNdDEFGANEL 606
Cdd:PRK13483  490 ITRVA-CPATqctdgpnqfGADP--TTYVNIDEAVTQGVEASLSYPITS-----TLSLSGNYTYTDSEQKS-GAYKGSPL 560

                         650       660       670       680       690
                  ....*....|....*....|....*....|....*....|....*....|
gi 2495644662 607 PGLPRHIYQAELKYQHASGF--YAGVDVRTASSTPVDYA--NSFQAPSYT 652
Cdd:PRK13483  561 NQLPKHLFQASLNWEPTDRLnsWARVNYRGEESQPTTGPssSSFIAPSYT 610
 
Name Accession Description Interval E-value
FecA COG4772
Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];
32-715 4.67e-134

Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];


Pssm-ID: 443804 [Multi-domain]  Cd Length: 681  Bit Score: 410.86  E-value: 4.67e-134
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662  32 AGQGASAAEPASEKEQRLETVVVRGEQKTEAQkakvkLEEVAGGTSLVDNAEVEKGRSSTLEDVLAFQPGV-IAQAAGGN 110
Cdd:COG4772     6 AAALLLAAAAAAEAATTLETVVVTGSRAAEAR-----LKDVPGSVSVVDREELENQAATSLREVLRRVPGVnVQEEDGFG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 111 DAIKISIRGSGANASPGyfregTKFLFDGLALTGP---GGTPYELLEMSGVNYTEVLRGANAFDYTALSLGGAINMVTHT 187
Cdd:COG4772    81 LRPNIGIRGLGPRRSRG-----ITLLEDGIPIAPApygDPAAYYFPDLERMERIEVLRGAAALRYGPQTVGGAINFVTRT 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 188 GHSSPGNYARFEAGSFGWRKQQLSTGGVVDDADYYISLSNSEREGYQDYTFNKAKGVVSNFGYRFSPKLDTRLIVRYREQ 267
Cdd:COG4772   156 IPTAFGGELRVTGGSFGYRRTHASVGGTVGNFGYLVEYSRKRGDGFRDNSGFDINDFNAKLGYRLSDRQELTLKFQYYDE 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 268 YHENASTLTRAQLKDDPSQPNPTTVAQRGDSTKngsiwVGSKTTYTLDDDSQVELGLVYHN------YRQILGKKSP--- 338
Cdd:COG4772   236 DANTPGGLTDAQFDADPRQSYRPADQFDTRRTQ-----LSLRYEHQLSDNTTLTTTAYYNDfsrnwyIRQNTADPNTpgl 310

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 339 -VIPNHWQWRDLNSSLRYLRSDRLFGLQSNTTLSF---SNTLHDRAEVKTYDGVSRKLLKETNYSGSFDTV-FAAGNELE 413
Cdd:COG4772   311 gLRGNPRGYRSYGIEPRLTHRFELGGVPHTLEVGLryhREEEDRKQYVNTYGQGRSGAGLRRDRRFSADALaAYAQNRFE 390

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 414 LTERLWLSSGLSLVNIRRDVDVNFSDRANTSPYPQHyKYDNWSlaPRLGLRYFLTPDIQLFGNVSRSIDPPSAWSISPSG 493
Cdd:COG4772   391 LTGRLTLTPGLRYEHIRRDRTDRYSTRTGGDDSGSN-SYSEFL--PGLGLLYQLTDNLQLYANVSRGFEPPTFGDLAYGN 467

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 494 PTNNyakTLVEQKGNTVEIGIRGARGP-LSGSLALYRSWLHDELLNVEIipargNSPAVTSTSNASATIHQGVEAGLDAE 572
Cdd:COG4772   468 GGNP---DLKPEKSWNYELGTRGRIGNgLSAEVALFYIDYDNELGSCSA-----AGGDRSTFTNAGETRHQGLELALDYD 539

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 573 LWRGvRGDTLVLRQAYTFNDFYYRN--DDEFGANELPGLPRHIYQAELKYQHaSGFYAGVDVRTASSTPVDYANSFQ--- 647
Cdd:COG4772   540 LLKG-GGLGLPLFAAYTYTDAEFTSdfGPVFAGNRLPYVPRHQLTAGLGYEH-GGWTANLNGRYVSEQFTDAANTVAdgs 617

                         650       660       670       680       690       700       710
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2495644662 648 ---APSYTVFGAKLGYeEPGQRWQVFLDLRNLTDEHYATTISPIYnargndAAALYSGDGFGAFTGVALRF 715
Cdd:COG4772   618 fgkIPSYTVLDLSASY-DFGKNLSLFAGVNNLFDKRYIASRAPNY------AAGIRPGPPRTVYAGLRLKF 681
CirA COG1629
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];
49-686 3.42e-86

Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];


Pssm-ID: 441236 [Multi-domain]  Cd Length: 644  Bit Score: 284.41  E-value: 3.42e-86
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662  49 LETVVVRgeqkteAQKAKVKLEEVAGGTSLVDNAEVEKGRSSTLEDVLAFQPGVIAQAAGGNDAiKISIRGSGANASpgy 128
Cdd:COG1629     1 LEEVVVT------ATRTDESLQDVPGSVSVISREQLEDQPATDLGDLLRRVPGVSVTSAGGGAG-QISIRGFGGGGN--- 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 129 freGTKFLFDGLALTGP--GGTPYELLEMSGVNYTEVLRGANAFDYTALSLGGAINMVTHTGHSSPGNYARFEAGSFGWR 206
Cdd:COG1629    71 ---RVLVLVDGVPLNDPsgGDGGLSYIDPEDIERVEVLRGPSSALYGSGALGGVINIVTKKPKDGKGGEVSASYGSYGTY 147

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 207 KQQLSTGGVVDDADYYISLSNSEREGYQDYTFNKAKGVVSNFGYRFSPKLDTRLIVRYREQYHENASTLTRAQLKDDPSQ 286
Cdd:COG1629   148 RASLSLSGGNGKLAYRLSASYRDSDGYRDNSDSDRYNLRAKLGYQLGDDTRLTLSASYSDSDQDSPGYLTLAALRPRGAM 227

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 287 PNPTTVAQRGDSTKNGSIWVGSKTTYTLDDDSQVELGLVYHNYRQILGKK-SPVIPNHWQWRDLNSSLRY------LRSD 359
Cdd:COG1629   228 DDGTNPYSNDTDDNTRDRYSLSLEYEHLGDGLKLSASAYYRYDDTDLDSDfTPTPADGGTLEQTDFDNRTyglelrLTYD 307

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 360 RLFGLQSNTT--LSFSNTLHDRAEVKTYDGVSRKLLKETNYSGSFDT----VFaAGNELELTERLWLSSGLSLVNIRRDV 433
Cdd:COG1629   308 LGFGGKHTLLvgLDYQRQDLDGSGYPLDLGSGSLPTLTSGADDDGTTtslaLY-AQDTYKLTDKLTLTAGLRYDYVSYDV 386

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 434 DvnfSDRANTSPYPQHYKYDNWSlaPRLGLRYFLTPDIQLFGNVSRSIDPPSAWSISPSG--PTNNYAKTLVEQKGNTVE 511
Cdd:COG1629   387 D---DTVTGTDSASGSRSYSAFS--PSLGLTYQLSPNLSLYASYSRGFRAPTFGELYANGtdPYSVGNPDLKPETSTNYE 461

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 512 IGIRGAR--GPLSGSLALYRSWLHDELLNVEIIPARGNSpavTSTSNASATIHQGVEAGLDAELWRGVRgdtlvLRQAYT 589
Cdd:COG1629   462 LGLRYRLldGRLSLSLALFYSDVDNEILSVPLPNDSGFS---TYYTNAGKARSYGVELELSYQLTPGLS-----LNASYS 533

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 590 FNDFYYRNDDEFGA----NELPGLPRHIYQAELKYQHASGFYAGVDVRTASSTPVDYANSFQAP-SYTVFGAKLGYeEPG 664
Cdd:COG1629   534 YTDAKFDDDTDGSAdldgNRLPGVPPLTANLGLTYEFPGGWSLGLGVRYVGDRYLDDANTQGAPgGYTLVDLGAGY-RFG 612

                         650       660
                  ....*....|....*....|..
gi 2495644662 665 QRWQVFLDLRNLTDEHYATTIS 686
Cdd:COG1629   613 DNLTLSLGVDNLFDKKYATSLS 634
FhuE COG4773
Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion ...
 18-691 2.65e-54

Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion transport and metabolism];


Pssm-ID: 443805 [Multi-domain]  Cd Length: 692  Bit Score: 198.58  E-value: 2.65e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662  18 PLWMAVGIGSLMMAAGQGASAAEPASEKEQRLETVVVRGEQKTE----------AQKAKVKLEEVAGGTSLVDNAEVEKG 87
Cdd:COG4773     1 AAALLAGSGLAAAAAGALAQAAAAAAAEATTLPEVTVTGTAEGTggytakssstATKLDTPLRETPQSVSVVTRQLIEDQ 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662  88 RSSTLEDVLAFQPGVIAQAAGGNDAIKISIRGSGANAspgyfregtkFLFDGLALTGPGGTPyelLEMSGVNYTEVLRGA 167
Cdd:COG4773    81 GATTLDDALRNVPGVTVSSYDGGGRDSFSIRGFSIDN----------YLRDGLPLGGFGGGQ---PDTANLERVEVLKGP 147

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 168 NAFDYTALSLGGAINMVTHTGHSSPGNYARFEAGSFGWRKQQLSTGGVVDDAD---YYISLSNSEREGYQDYTFNKAKGV 244
Cdd:COG4773   148 AGLLYGAGSPGGLVNLVTKRPTAEPQGEVSLSAGSWDTYRATADVGGPLNEDGtlrYRLNAAYEDGDSFRDGVDNRRTLI 227

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 245 VSNFGYRFSPklDTRLIVRYreQYHENASTLTRAQLKDDPSQ---PNPTTVAQRGDSTKNGSIWVGSKTTYTLDDDSQVE 321
Cdd:COG4773   228 APSLDWDLTD--DTTLTLGA--EYQDDDSTGDRGFLPLDGTLldlPRSTNLGEPWDYYDTETTTLFAELEHRFNDDWSLR 303

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 322 LGLVYHNYRQILGkkspvipNHWQWRDLNSSLRYLRSDRLFGLQSNTTLSFSNTLhdRAEVKTYD-------GVSRKLLK 394
Cdd:COG4773   304 ANARYSDSDRDGR-------SAYAYGAPDAATGTLTRYASARDGDSRSDSLDANL--NGKFETGGlehtllvGADYSRYD 374

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 395 ETNYSGSFDTV----------------------------FAAGNELELTERLWLSSGLSLVNIRRDVDVNFSDRANTspy 446
Cdd:COG4773   375 SDSDSATAGTIniynpvygnlpepdfdasdtdtttrqtgLYAQDQISLTDRLSLLLGGRYDWYETDSTNRLGGSTTS--- 451

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 447 pqhYKYDNWSlaPRLGLRYFLTPDIQLFGNVSRSIDPPSAwsispsgpTNNYAKTLVEQKGNTVEIGIRG--ARGPLSGS 524
Cdd:COG4773   452 ---YDDSAFT--PRAGLVYDLTPGLSLYASYSESFEPQSG--------ADNNGNPLDPETGKQYEAGVKGelFDGRLNAT 518

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 525 LALYRswLHDEllNVeiipargnspAVTSTSNASATI------HQGVEAGLDAELWRGvrgdtLVLRQAYTFNDFYYRND 598
Cdd:COG4773   519 LAVFD--ITQK--NV----------ATTDPDNPNFYVqvgevrSRGVELELSGELTPG-----LNLIAGYTYTDAKITKD 579

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 599 DEFGA-NELPGLPRHIYQAELKYQHAS----GFYAGVDVRTASSTPVDYANSFQAPSYTVFGAKLGYeEPGQRWQVFLDL 673
Cdd:COG4773   580 ADALEgKRLTNVPRHTASLWTTYRFPSgalkGLGLGGGVRYVGERYGDAANTFTLPSYTLVDAGARY-DLGKNWTLQLNV 658

                         730
                  ....*....|....*...
gi 2495644662 674 RNLTDEHYATTISPIYNA 691
Cdd:COG4773   659 NNLFDKKYYASSGSRGYV 676
Fiu COG4774
Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism];
89-691 3.43e-50

Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism];


Pssm-ID: 443806 [Multi-domain]  Cd Length: 639  Bit Score: 185.85  E-value: 3.43e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662  89 SSTLEDVLAFQPGVIAQAAGGNDAIKISIRGSGANASpgyfregtkFLFDGLALtgPGGTPYELLEMSGVnytEVLRGAN 168
Cdd:COG4774    26 ATSLADALRNVPGVTFGAGEGGNGDSFSIRGFSASGD---------IYVDGLRD--PGQYRRDTFNLERV---EVLKGPA 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 169 AFDYTALSLGGAINMVTHTGHSSPGNYARFEAGSFGWRKQQLSTGGVV-DDADYYISLSNSEREGYQDYTFNKAKGVVSN 247
Cdd:COG4774    92 SVLYGRGSPGGVINLVTKRPTDEPFTEVTLTYGSDGQRRATLDVNGPLgDDLAYRLNGMYRDSDSYRDGVDNDRWGIAPS 171

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 248 FGYRFSPklDTRLIVRYREQYHENA------STLTRAQLKDDPSqpnpTTVAQRGDSTKNGSIWVGSKTTYTLDDDSQVE 321
Cdd:COG4774   172 LTWRLGD--RTRLTLDYEYQDDDRTpdygvpAVANGRPVDVDRS----TFYGQPDDYSDSETDSATLRLEHDFNDNWTLR 245

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 322 LGLVYHNYRQILGKKSPVIPNhwQWRDLNSSLRYLRSD-RLFGLQSN-----TTLSFSNTL-------HDRAEVKTYDG- 387
Cdd:COG4774   246 NALRYSDYDRDYRNTYPTGGN--ATGTVTRSAYRRDQDnDTLSNQTDltgkfDTGGVKHTLlagveysREDSDNARYSGg 323

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 388 ----------------VSRKLLKETNYSGSFDTV-FAAGNELELTERLWLSSGLslvniRRD-VDVNFSDRAnTSPYPQH 449
Cdd:COG4774   324 gtaptvnlynpvygapVTGPTLGGADNDSRTDTTgLYLQDTISLTDRWSLLAGL-----RYDrFDTDYTDRT-TGATTSS 397

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 450 YKYDNWSlaPRLGLRYFLTPDIQLFGNVSRSIDPPSAwsispSGPTNNYAKTLVEQKGNTVEIGIR--GARGPLSGSLAL 527
Cdd:COG4774   398 YDDSAFS--PRAGLVYKPTPNLSLYASYSTSFNPGGG-----APSLSNAGQALDPEKSRQYEVGVKwdLLDGRLSLTAAL 470

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 528 YRSWLHDELLNveiipargNSPAVTSTSNASATIHQGVEAGLDAELWRGVRgdtlvLRQAYTFNDFYYRNDDEFGA--NE 605
Cdd:COG4774   471 FRIEKTNVRTT--------DPANPGVYVQTGEQRSRGVELEATGELTPGWS-----VLAGYTYLDAEITKSANAANvgNR 537

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 606 LPGLPRHIYQAELKYQ-HASGFYAGVDVRTASSTPVDYANSFQAPSYTVFGAKLGYeEPGQRWQVFLDLRNLTDEHYATT 684
Cdd:COG4774   538 LPNVPRHSASLWTTYDlPLPGLTLGGGVRYVGSRYADAANTVKLPSYTRFDAGASY-RLNKNLTLRLNVNNLTDKRYYAS 616


                  ....*..
gi 2495644662 685 ISPIYNA 691
Cdd:COG4774   617 AYGSGYV 623
FepA COG4771
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and ...
 25-670 2.97e-47

Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism];


Pssm-ID: 443803 [Multi-domain]  Cd Length: 612  Bit Score: 176.97  E-value: 2.97e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662  25 IGSLMMAAGQGASAAEPASEKEQRLETVVVRgeqkteAQKAKVKLEEVAGGTSLVDNAEVEKGRSSTLEDVLAFQPGVIA 104
Cdd:COG4771     3 LASLLLLLALAAQAADALAEDATELEEVVVT------ATRTEQSLSDAPASVSVITAEEIEKLGATDLADALRLLPGVSV 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 105 QAAGGNDAIK-ISIRGSGANaspgyfreGTKFLFDGLALTGP---GGTPYELLEMSGVNYTEVLRGANAFDYTALSLGGA 180
Cdd:COG4771    77 TRSGGRGGSSgISIRGLGGD--------RVLVLIDGVPVNNPalgGGGDLSYIPPDDIERIEVIRGPASALYGSDAIGGV 148

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 181 INMVTHTGHSSPGNYARFEAGSFGWRKQQ--LSTGGVVDDADYYISLSNSEREGYQDYTFNKAKGVVS--------NFGY 250
Cdd:COG4771   149 INIITKKPTDELEGSVSLGYGSNGNGTYSgsLSLGGPGDKLSFLLSGSYRDRDGYLDYRNGGFVGNSGyerynlnaKLGY 228

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 251 RFSPKLDTRLIVRYREQYHENASTLTRAQLKDDPSQPNPTTVAQRGDstkngsiwVGSKTTYTLDDDSQVELGLVYHNYR 330
Cdd:COG4771   229 RLSDNHRLSLSGGYSRQDRDGGPPTLGDTEISSDNAGDRDTTTDRGN--------YSLRYNGDLGDNLDLSLYYSRTDRD 300

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 331 QILGKKSPVIPNhwqWRDLNSSLRYLRSDRLFGLQSNTTLSFSntlhdrAEVKTYDGVSRKLLKETNYSGSFDTVFaAGN 410
Cdd:COG4771   301 STNGSLGGSTGS---FSDSDDTTYGLELDLTYPLGGNHTLTLG------AEYRYDDLDSSSFLGGADASRDTYGLF-AQD 370

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 411 ELELTERLWLSSGLslvniRRDvdvNFSDRANTSpypqhykYDNWSlaPRLGLRYFLTPDIQLFGNVSRSIDPPSAWSIS 490
Cdd:COG4771   371 EWKLTDKLTLTAGL-----RYD---YYSTFGASN-------YTAFS--PRLGLRYDLSDNLTLRASYGRGFRAPSLAELY 433

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 491 PSGPTNNYAKT-----LVEQKGNTVEIGIRG--ARGPLSGSLALYRSWLHDELLNVEIIPARGNspaVTSTSNASATIHQ 563
Cdd:COG4771   434 GSGTGTPGRYVlgnpdLKPETSDNYELGLEYrlGNGGLSLSLTGFYTDIKDLIVLVPVGPGPGD---VLQYENVGKARTY 510

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 564 GVEAGLDAELWRGVRGDTlvlrqAYTFNDfyYRNDDEFGANELPGLPRHIYQAELKYQHASGFYAGVDVRTASSTPVDY- 642
Cdd:COG4771   511 GLELELKYRLGKGLTLTA-----SYTYLD--SKIDDGDTGEPLPNVPPHKANLGLDYRLPKWWLLLLLTRYYGGRYVTPp 583

                         650       660       670
                  ....*....|....*....|....*....|
gi 2495644662 643 --ANSFQAPSYTVFGAKLGYeEPGQRWQVF 670
Cdd:COG4771   584 sgRLEGYTPGYTLLDLRASY-KLTKNLTLS 612
ligand_gated_channel cd01347
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ...
 75-715 9.33e-42

TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.


Pssm-ID: 238657 [Multi-domain]  Cd Length: 635  Bit Score: 161.47  E-value: 9.33e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662  75 GTSLVDNAEVEKGRSSTLEDVLAFQPGVIAQAAGGNDAIKISIRGSGANaspgyfreGTKFLFDGLALTGPGGT------ 148
Cdd:cd01347     1 SVSVITAEDIEKQPATSLADLLRRIPGVSVTRGGGGGGSTISIRGFGPD--------RTLVLVDGLPLASSNYGrgvdln 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 149 --PYELLEmsGVnytEVLRGANAFDYTALSLGGAINMVT------HTGHSSPGNYARFEAGSFGWRKQQLSTGGVVDDAD 220
Cdd:cd01347    73 tiPPELIE--RV---EVLKGPSSALYGSGAIGGVVNIITkrptdeFGGSVTAGYGSDNSGSSGGGGFDVSGALADDGAFG 147

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 221 YYISLSNSEREGYQ------DYTFNKAKGVVSNFGYRFSPKLDTRLIVRY-REQYHENASTL-TRAQLKDDPSQPNPTTV 292
Cdd:cd01347   148 ARLYGAYRDGDGTIdgdgqaDDSDEERYNVAGKLDWRPDDDTRLTLDAGYqDQDADGPGGTLpANGTGSSLGGGPSSNTN 227

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 293 AQRGDSTKNGSIWVGSKT-TYTLDDDS-QVELGLVYHNYRQilgKKSPVIPNHWQWRDLNSSLRYLRSDRL----FGLQS 366
Cdd:cd01347   228 GDRDWDYRDRYRKRASLGlEHDLNDTGwTLRANLSYSYTDN---DGDPLILNGGNNAAGGDLGRSGYSSERdttqLGFDA 304

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 367 NTTLSFsNTLHDRAEVKTYDGVSRKLLKETNYSgsfdtVFAAGNeLELTERLWLSSGLslvniRRD-VDVNFSDRANTSP 445
Cdd:cd01347   305 GLNAPF-GTGPVAHTLTLGVEYRREELDEKQTA-----LYAQDT-IELTDDLTLTLGL-----RYDhYDQDSKDTIAGGT 372

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 446 YPQhYKYDNWSlaPRLGLRYFLTPDIQLFGNVSRSIDPPSAWSISPSG---PTNNYAKTLVE-QKGNTVEIGIRGARGP- 520
Cdd:cd01347   373 TAK-KSYSHWS--PSLGLVYKLTDGLSLYASYSQGFRAPSLGELYGGGshgGTAAVGNPNLKpEKSKQYELGLKYDPGDg 449

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 521 LSGSLALYRSWLHDELLNVeiiPARGNSPAVTSTSNASATIHQGVEAGLDAELWRGVRGDTlvlrqAYTFNDFYY-RNDD 599
Cdd:cd01347   450 LTLSAALFRIDIKNEIVST---PTNTGLGLVTVYVNGGKARIRGVELEASYDLTDGLGLTG-----SYTYTDTEVkRTDG 521

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 600 EFGANELPGLPRHIYQAELKYQH-ASGFYAGVDVRTASSTPVDYA---NSFQAPSYTVFGAKLGYeEPGQRWQVFLDLRN 675
Cdd:cd01347   522 ATTGNRLPGIPKHTANLGLDYELpDEGLTAGGGVRYRGKQYADTAngnNTVKVPGYTLVDLSASY-QFTKNLTLRLGVNN 600

                         650       660       670       680
                  ....*....|....*....|....*....|....*....|
gi 2495644662 676 LTDEHYATTISPIYNargndAAALYSGDGFGAFTGVALRF 715
Cdd:cd01347   601 LFDKDYYTSLSVRGS-----GLYGYYGPGRTYYLSVSYKF 635
TonB_dep_Rec pfam00593
TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
 246-714 3.08e-35

TonB dependent receptor; This model now only covers the conserved part of the barrel structure.


Pssm-ID: 395474 [Multi-domain]  Cd Length: 475  Bit Score: 139.91  E-value: 3.08e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 246 SNFGYRFSPKLDTRLIVRYREQYHENASTLTRAQLKDDPSQPNPTTVAQRGDSTKNGSIWVGSKTTYTLDDD----SQVE 321
Cdd:pfam00593   3 QLSLDLLGDDTLLTLGYDYSRYTDGLDLGLTLDGYGNDGGYLGDRPLYYGRDYSDTDRKRLSLGYDYDLGDGlswlSTLR 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 322 LGLVYHNYRQILGKKSPVIPNHWQWRDLNSSLRYLRSDRLFGLQSNTTLSFSNTLHDRAEVKTYDGVSRKLLKETNYSGS 401
Cdd:pfam00593  83 LGLRYSSLDGDYTSNSSGLSGAGDYLSDDRLYGLYGLDGDLELSLDLSHDLLLGVELRTAGLDYRRLDDDAYDPYDPANP 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 402 FDTVFA----------AGNELELTERLWLSSGLSLVNIRRDVDVNFSDRANTSpypqhYKYDNWSlaPRLGLRYFLTPDI 471
Cdd:pfam00593 163 SSSSYSdtttdsyglyLQDNIKLTDRLTLTLGLRYDHYSTDGDDGNGGGDNFS-----RSYSAFS--PRLGLVYKPTDNL 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 472 QLFGNVSRSIDPPSAWSISPSGPTNNYA------KTLVEQKGNTVEIGIRGARGPLSGSLALYRSWLHDELLNVEIIPar 545
Cdd:pfam00593 236 SLYASYSRGFRAPSLGELYGSGSGGGGGavaggnPDLKPETSDNYELGLKYDDGRLSLSLALFYIDIKNLITSDPDGP-- 313

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 546 GNSPAVTSTSNASATIHQGVEAGLDAELWRgvrgdTLVLRQAYTFNDFYYRNDDEFGANELPGLPRHIYQAELKYQHASG 625
Cdd:pfam00593 314 GLGGTVYTYTNVGKARIRGVELELSGRLWG-----LGLSGGGYTYTDADDDADADDTGNPLPNVPRHTANLGLTYDFPLG 388

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 626 -FYAGVDVR---TASSTPVDYANSFQAPSYTVFGAKLGYeEPGQRWQVFLDLRNLTDEHYATtispiYNARGNDAAALYS 701
Cdd:pfam00593 389 gWGARLGARyvgSGERRYGDAANTFKTPGYTLVDLSAGY-RLNKNLTLRLGVNNLFDKYYKR-----YYSSGGGNLGGYP 462

                         490
                  ....*....|...
gi 2495644662 702 GDGFGAFTGVALR 714
Cdd:pfam00593 463 GPGRTFYLGLSYK 475
BtuB COG4206
Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism];
52-266 6.07e-24

Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism];


Pssm-ID: 443355 [Multi-domain]  Cd Length: 276  Bit Score: 102.26  E-value: 6.07e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662  52 VVVrgeqktEAQKAKVKLEEVAGGTSLVDNAEVEKGRSSTLEDVLAFQPGVIAQAAGGNDAIK-ISIRGSGANaspgyfr 130
Cdd:COG4206     1 VVV------TATRLEQSKSDLTGSVTVIDAEELERSGATSLADALRRVPGVQVSSSGGPGSAAsISIRGLGSN------- 67

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 131 eGTKFLFDGLALTGP--GGTPYELLEMSGVNYTEVLRGANAFDYTALSLGGAINMVTHTGHSSPGNYARFEAGSFGWRKQ 208
Cdd:COG4206    68 -QTLVLIDGVPLNDPslGGVDLSLIPPDDIERIEVLKGAASALYGSDAIGGVINITTKKGKKGFKGSVSASYGSFGTRRL 146

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2495644662 209 QLSTGGVVDDADYYISLSNSEREGYQDYTFN-------KAKGVVSNFGYRFSPKLDTRLIVRYRE 266
Cdd:COG4206   147 SASLSGGAGKFSYSLSASYRRSDGYRYNDPDlrnndgyENTSLNARLGYKLGDNGSLSLSGGYSD 211
TonB-siderophor TIGR01783
TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of ...
 71-701 2.42e-22

TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of TonB-dependent outer membrane siderophore receptors. It has no overlap with TonB receptors known to transport other substances, but is likely incomplete due to lack of characterizations. It is likely that genuine siderophore receptors will be identified which score below the noise cutoff to this model at which point the model should be updated. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273805 [Multi-domain]  Cd Length: 651  Bit Score: 102.11  E-value: 2.42e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662  71 EVAGGTSLVDNAEVEKGRSSTLEDVLAFQPGVIAQAAGG-NDAIKISIRGSGANASPGYFRegtkflFDGLALTGPGGtp 149
Cdd:TIGR01783   1 DIPQSVSVITRQELEDQQAGSLSEALQRVPGVVVGGSGGtTQFGNITIRGFGLEVDIDNVY------LDGVPLLSRGN-- 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 150 YELLEMSGVNYTEVLRGANAFDYTALSLGGAINMVTHTGHSSPGNYARFEAGSFgwrkqqlstGGVVDDADYYISLSNSE 229
Cdd:TIGR01783  73 LAIVDPAMVERVEVLRGPASLLYGGSAPGGVINIVTKRPQDEPKGSVTFGAGTR---------SGYRTAFDLGGPLGADG 143

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 230 regyqdytfnkakgvvsNFGYRFSPkldtrlIVRYREQYHENASTLTRAQlkddpsqpNPTTVAQRGDSTKNGSIWvgsk 309
Cdd:TIGR01783 144 -----------------TFRGRLNG------ARQDGDSFYDGAGEETRLG--------ATATDWQLDDRTLLRLGA---- 188

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 310 tTYTLDDDSQVELGLVYHNYRQILGKKSPVIPNHWQWRDLNS--SLRY-LRSDRLFGL--QSNTTLSFSNTLHDRAEVK- 383
Cdd:TIGR01783 189 -YYQKERDRGGYGGLPASGGTSGRDLSSDRYLGTSSNRNYDDreYLSYgLSLEYQFNDvwTGKQNLRYSYFDTDSNQVQa 267

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 384 --------------TYDGVSRKLLK-ETNYSGSFDT------VFAAGNELELTERLWLSSGLSLVNI---------RRDV 433
Cdd:TIGR01783 268 sgyssdgglfgrslTVVNVKQDRVQiDAGLDGEFETgpiehdLLLGVSYGQRTTNRFNNTGYPSDNIysltatssaRTDI 347

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 434 DVNFSDRANTSPYPQHYKY--------DNWSLA-----------------------------PRLGLRYFLTPDIQLFGN 476
Cdd:TIGR01783 348 GDSPKDRALSSTTKALNGValqrillaDKWTLTlggrydsvdvksnngvagstgkrddsqftPSLGVAYKPTDDWSLYAS 427

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 477 VSRSIDPPsawSISPSGPTNNyAKTLVEQKGNTVEIGIRGARG-PLSGSLALYRSWLHDELLNveiipargNSPAVTSTS 555
Cdd:TIGR01783 428 YAESFKPG---GYYPKGAGNS-GDILEPEKGKNYELGVRYDLGdSLLATAALFRITKDNQLVQ--------DPVNGTFSV 495

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 556 NASATIHQGVEAGLDAELWRGVRgdtLVLRQAYTFNDFYYRNDDEFGANELPGLPRHIYQAELKYQ-----HASGFYAGV 630
Cdd:TIGR01783 496 NAGKTRNRGVELEARGYLTPGLS---LSAGYTYTDAEFTEDTNGDTQGNTVPFVPKHTASLWASYAppvgdNGLTLGGGV 572

                         650       660       670       680       690       700       710
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2495644662 631 dVRTASSTPVDyANSFQAPSYTVFGAKLGYE-EPGQRWQVFLDLRNLTDEHYATTispiYNARGNDAAALYS 701
Cdd:TIGR01783 573 -QYTGKAYVDG-GNTGKVPSYTVVDLSVRYDlTKKKNLTLALNVNNLFDRDYYTS----GYRWGPSAYIYPG 638
TonB-hemlactrns TIGR01786
TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; This model ...
 50-687 4.19e-13

TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; This model represents a family of TonB-dependent outer membrane receptor/transporters acting on iron-containing proteins such as hemoglobin, transferrin and lactoferrin. Two subfamily models with a narrower scope are contained within this model, the heme/hemoglobin receptor family protein model (TIGR01785) and the transferrin/lactoferrin receptor family model (TIGR01776). Accessions which score above trusted to this model while not scoring above trusted to the more specific models are most likely to be hemoglobin transporters. Nearly all of the species containing trusted hits to this model have access to hemoglobin, transferrin or lactoferrin or related proteins in their biological niche. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273808 [Multi-domain]  Cd Length: 715  Bit Score: 72.83  E-value: 4.19e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662  50 ETVVVRGeqKTEAQKAKVKLEEVAGGTSLVDNAEVEKGRSSTLEDVLAFQPGVIAQAAGGNDAIKISIRGSGAN------ 123
Cdd:TIGR01786   1 DTITVTA--TRTADPQRRDLSVTPASVSVISREQLKSQQVRNLRDLLRYEPGVSVVEGGRGGSQGINIRGLDKNrvavlv 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 124 --ASPGYFREGTKFLFDGLaltgpggtpyELLEMSGVNYTEVLRGANAFDYTALSLGGAINMVTH--------------- 186
Cdd:TIGR01786  79 dgIRQNTSYGGQGSTFYAI----------NSIDPELIKSIEIVKGASSSLYGSGALGGVVAFRTKdaadllkpgkdlggl 148

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 187 --TGHSSpGNYARFEAGSFGWRKQQLS--------TGGVVDDADYYISLSNSEReGYQDYTFNKAKGVVSNFGYRFSPKL 256
Cdd:TIGR01786 149 skLGYSS-ANNRFTQSVAAAGRNDDVDalvqatyrRGHELKNGNKANIGNESKR-SKPNPSDYKSQSFLAKLGWQLNDAH 226

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 257 DTRLIVRYREQYHENASTLTRAQLKDDPSQPNPTTVAQRGDSTKNgsiwvgsKTTYTLD-----DDS---QVELGLVYHN 328
Cdd:TIGR01786 227 RLGLSLEYTQTDYDEPEMTNTSYLTKPLGAPLLSSTVVLGDSKTR-------DRRTGLDyelnpDNSwldTVKLALDKQY 299

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 329 YRQILGKKSPVIPNHwQWRDLNSSLRYLRSDRLFGLQSNTTLSFSNTLH------DRAEVK-TYDGVSRKLLKET----- 396
Cdd:TIGR01786 300 IQLYNYLNATSASDY-PGVDKNGRYKDKYDYYTLGFDTNNKIEFSVHSLsltyglDRFKDKvSTGDSRRNLPTAAynlyg 378

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 397 ------NYSGSFDTVFAAgNELELTERLWLSSGLSLVNIRRDVDVNFSDrantSPYPQHYKYDNWSlaPRLGLRYFLTPD 470
Cdd:TIGR01786 379 yegenrPVKGSNFGLFLQ-DNIKLGDWLSLSAGLRYDHYKTDPKADESK----DYGAISKTYSRWS--PSLGLTYKPTPW 451

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 471 IQLFGNVSRSIDPPSA-----WSISPSGPTNNYAKT--LVEQKGNTVEIGIRGARGPLSGSLALYRSWLHDELLNVEIIP 543
Cdd:TIGR01786 452 LTLYYSYSQGFRAPSFdelygTGAHPGGGPYTFLPNpnLKPETSKNWEIGINLHFDQLDFKVSYFRNDYKDFIDLGIGVT 531

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 544 ARGN-----SPAVTSTSNASATIHQGVEAGLD---AELWRGVRGDTLVLRQAYTfndfyyRNDDEFGANELPGLPRHIYQ 615
Cdd:TIGR01786 532 AKGNmaqvgSNTITNYVNIDNARIRGIELSGRydlGSFFSGPDGWTTTLKYGYT------KGKDSDTNPWLNAITPLKVV 605

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 616 AELKYQHASG---------FYAGVDVRTASSTPVDY-----ANSFQAPSYTVFGAkLGYEEPGQRWQVFLDLRNLTDEHY 681
Cdd:TIGR01786 606 LGLGYDHPDEkwgvgltltFSGAKDAVDAYATYYENgeaakAGPLRTPSYTVVDL-YGYYKPNKNLTLRFGVYNLLDRKY 684


                  ....*.
gi 2495644662 682 ATTISP 687
Cdd:TIGR01786 685 TTWESA 690
Plug pfam07715
TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently ...
 68-180 4.34e-13

TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently folding subunit of the TonB-dependent receptors. It acts as the channel gate, blocking the pore until the channel is bound by ligand. At this point it under goes conformational changes opens the channel.


Pssm-ID: 462243 [Multi-domain]  Cd Length: 107  Bit Score: 65.75  E-value: 4.34e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662  68 KLEEVAGGTSLVDNAEVEKGRSSTLEDVLAFQPGVIAQAAGGNDAIKISIRGSGANaspgyfreGTKFLFDGLALTGPGG 147
Cdd:pfam07715   1 DLRDTPGSVSVVTAEDIEDQGATNLADALRGVPGVSVSSGGGGGGSSISIRGFGSN--------RVLVLVDGVPLNSGGG 72

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 2495644662 148 TPYEL--LEMSGVNYTEVLRGANAFDYTALSLGGA 180
Cdd:pfam07715  73 GSVDLnsIDPEDIERVEVLKGPASALYGSGAIGGV 107
TonB-hemin TIGR01785
TonB-dependent heme/hemoglobin receptor family protein; This model represents the ...
 49-693 5.50e-12

TonB-dependent heme/hemoglobin receptor family protein; This model represents the TonB-dependent outer membrane heme/hemoglobin receptor/transporter found in bacteria which live in contact with animals (which contain hemoglobin or other heme-bearing globins) or legumes (which contain leghemoglobin). Some species having hits to this model such as Nostoc, Caulobacter and Chlorobium do not have an obvious source of hemoglobin-like proteins in their biological niche and so the possibility exists that they act on some other substance. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273807 [Multi-domain]  Cd Length: 665  Bit Score: 68.96  E-value: 5.50e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662  49 LETVVVrgeqktEAQKAKVKLEEVAGGTSLVDNAEVEKGRSSTLEDVLAFQPGVIAQAAGGNDAIKISIRGSGANaspgy 128
Cdd:TIGR01785   1 LDTVTV------TATRTRQVLSEAPASVSVISGEQIESKQANNLADALNTVPGVDVTGGGRPPGQSINIRGLQDN----- 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 129 freGTKFLFDGL---ALTGPGGTPYELLEMSGVNYTEVLRGANAFDYTALSLGGAINMVTHT------GHSSPGNYARFE 199
Cdd:TIGR01785  70 ---RVLVVVDGArqnYQRGGAHNGSLFVDPELLKRIEIVKGPSSSLYGSGALGGVVAFRTKDaadllrPGQLFGGLAKLS 146

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 200 AGSFGWRKQQLSTGGV--VDDADYYISLSNSEREGYQD-------YTFNKAKGVVSNFGYRFSPKLDTRLIVRYRE---- 266
Cdd:TIGR01785 147 YGSNNNSFGGSVAVAGrlDDNLDALVAATYRDGGNYRNgnkeeatNSAYVQKNLLAKLGWQLDDAQRLEFSYFTTEgsld 226

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 267 ----QYHENASTLTRAQLKDDPSQPNPTTVAQRGDSTKNGSIWVGSKTTYTLDDDSqvelglvyHNYR--QILGKKSpvi 340
Cdd:TIGR01785 227 eaqnSGPGTEYVLGSSSTLLASSTRDRSATLTYNWTPEDNPWLDATASLYYNRTEN--------DNDRsaRGVGREE--- 295

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 341 pnhwqWRDLNSSLRYLRSDRLFGLQSNTTLSFSNTLHD---RAEVKTYDGVSRKLLKETNYSGSFDTVFAAGNELELTER 417
Cdd:TIGR01785 296 -----GYQYTTYGATLQNTSRFDVASWSTLTYGVDWMKdkrRTESFDPNSVTTIVPNPPSAKEYFFGLFLQDNIPLLDDR 370

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 418 LWLSSGLslvniRRDvDVNFSDRANTSPYPQHYKYDNWSlaPRLGLRYFLTPDIQLFGNVSRSIDPPSAW-----SISPS 492
Cdd:TIGR01785 371 LTLSAGL-----RYD-HYKLSPKTTADTEAVDRSYSRWS--PSLGLSYKPVDWLTLYASYSQGFRAPSIDelygtGDHPG 442

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 493 GPTNNYAK---TLVEQKGNTVEIGIRG-------ARGPLSGSLALYRSWLHDELLNVEIIPARGNSPAVTSTS---NASA 559
Cdd:TIGR01785 443 TPGGYTFApnpNLKPETSKTWELGANLsfdnlllDNDQLQFKVAYFYNDVKDFIDLTIGVTDNVTAGMNNITQyvnIDGA 522

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 560 TIhQGVEAGL--DAELWRGvrgdtlvlRQAYTFNDFYYRNDDEFGANELP-----GLPRHIYQAELkYQHASGFYAGVDV 632
Cdd:TIGR01785 523 RI-RGIEASAsyDAGLWAT--------GLSYGYTIGKDQNTNQWLSNIPPlklvvTVGYRFPDRRL-DLGAKAAYYERQS 592

                         650       660       670       680       690       700
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2495644662 633 RTASSTPVDYANSFQAPSYTVFGAKLGYeepgqRWQVFLDLR------NLTDEHYATTISPIYNARG 693
Cdd:TIGR01785 593 ESPTTEDVAANGLLTTPGYTVVDLYATY-----QPNAVKGLTvrfgvnNLTDRKYTPAQSVPGAGPG 654
PRK13483 PRK13483
ligand-gated channel protein;
24-652 9.18e-12

ligand-gated channel protein;


Pssm-ID: 184080 [Multi-domain]  Cd Length: 660  Bit Score: 68.26  E-value: 9.18e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662  24 GIGSLMMAAGQGASAAEPASEKEQRLETVVVrgeqkTEAQKAKVkLEEVAGGTSLVDNAEVEKGRSSTLEDVLAFQPGVI 103
Cdd:PRK13483    8 VISALCLLPAVFVTHALAQAAPDKTMETVVV-----TASGYEQQ-IRDAPASISVITREDLENRFYRDLTDALLDVPGVV 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 104 AqaAGGNDAIKISIRGSGANaspgYfregTKFLFDGLALT---------GPGGTPYELLEMSGVNYTEVLRGANAFDYTA 174
Cdd:PRK13483   82 V--TGGGDRTDISLRGMGSQ----Y----TLILVDGKRQSsretrpnsdGPGVEQAWTPPLAAIERIEVIRGPMSSLYGS 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 175 LSLGGAINMVTH-TGHSSPGNyARFEAgsfgwRKQQLSTGGVVDDADYYISLS-NSEREG---YQDYTFNKAKGVVSNFG 249
Cdd:PRK13483  152 DAIGGVINIITRkVPNEWQGE-VRLDT-----TLQENSDSGNVYQANFFVNGPlIKDLLGlqlYGQYTQREEDDIEGGYR 225

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 250 YRFSPKLDTRLIVRYREQYHENASTLTRAQLKD-------DPSQPNPTTVAQRGDSTkngsiwvgSKTTYtldDDSQVEL 322
Cdd:PRK13483  226 DKDARSLTAKLALTPNEDHDIMLEVGTSNQERDstvgktvAPLAPGESCGRRGCPES--------STTEY---ERSTVSL 294

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 323 GlvyHNYRqilgkkspvipnhWQWRDLNSSLRY----------------LRSDRLFGLQSNTTLSF-SNTLHDRAEVKTy 385
Cdd:PRK13483  295 S---HTGR-------------WDFGTSDTYIQHeefdnksremkikntdFQSSLVAPLGQEHTLTFgAAYNHQDLTDET- 357

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 386 dgvSRKLLKETNYSGSFDTVFAAgNELELTERLWLSSGLslvniRRDVDVNFSdrantspypQHYK---YDNWSLAPRLG 462
Cdd:PRK13483  358 ---SNQISDLTDISRTQWAVFSE-DEWRIADDFALTGGL-----RLDHDENFG---------GHVSprvYGVWNLAPSWT 419

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 463 LRyfltpdiqlfGNVSRSIDPPSAWSISP-----SGPTNNYAK-TLVEQKGNTVEIGIRGARGP-LSGSLALYRSWLHDE 535
Cdd:PRK13483  420 VK----------GGVSTGFRAPSLRQTTPdwgqvSRGGNIYGNpDLKPETSLNKELGLYYDLGSgLTASLTVFYNEFKDK 489

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 536 LLNVEiIPAR---------GNSPavTSTSNASATIHQGVEAGLDAELWRgvrgdTLVLRQAYTFNDFYYRNdDEFGANEL 606
Cdd:PRK13483  490 ITRVA-CPATqctdgpnqfGADP--TTYVNIDEAVTQGVEASLSYPITS-----TLSLSGNYTYTDSEQKS-GAYKGSPL 560

                         650       660       670       680       690
                  ....*....|....*....|....*....|....*....|....*....|
gi 2495644662 607 PGLPRHIYQAELKYQHASGF--YAGVDVRTASSTPVDYA--NSFQAPSYT 652
Cdd:PRK13483  561 NQLPKHLFQASLNWEPTDRLnsWARVNYRGEESQPTTGPssSSFIAPSYT 610
PRK13484 PRK13484
IreA family TonB-dependent siderophore receptor;
43-628 5.88e-06

IreA family TonB-dependent siderophore receptor;


Pssm-ID: 139605 [Multi-domain]  Cd Length: 682  Bit Score: 49.62  E-value: 5.88e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662  43 SEKEQRLETVVVRGEQKTEAQKakvkleEVAGGTSLVDNAEVEKGRSSTLEDVLAFQPGViaQAAGGNDAIKISIRGSga 122
Cdd:PRK13484   24 ASSDKKEDTLVVTASGFTQQLR------NAPASVSVITSEQLQKKPVSDLVDAVKDVEGI--SITGGNEKPDISIRGL-- 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 123 nasPGyfrEGTKFLFDGLALTG----PGGTP-YE---LLEMSGVNYTEVLRGANAFDYTALSLGGAINMVThtghsSPGN 194
Cdd:PRK13484   94 ---SG---DYTLILVDGRRQSGresrPNGSGgFEagfIPPVEAIERIEVIRGPMSSLYGSDAIGGVINIIT-----KPVN 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 195 YARFE-AGSFGWRKQQLSTGGVVDDADYYISLSNSE-REGYQDY---------------TFNKAKGVVSNFgyRFSPKLD 257
Cdd:PRK13484  163 NQTWDgVLGLGGIIQEHGKFGNSTTNDFYLSGPLIKdKLGLQLYggmnyrkedsisqgtPAKDNKNITATL--QFTPTES 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 258 TRLIVRYREQYHENAST----LTRAQLKDDPSQPNpttvaQRGDSTKNGSIWVgskTTYTLDDDS-QVELGLVYHNYRQI 332
Cdd:PRK13484  241 QKFVFEYGKNNQVHTLTpgesLDAWTMRGNLKQPN-----SKRETHNSRSHWV---AAWNAQGEIlHPEIAVYQEKVIRE 312

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 333 L--GKKSPVIPNHWQWRDLNSSLRYLRSDRLF-GLQSNTTLSFSNTlHDRAEVKTYDGVSRKLLKETNYSGSFDTVFAAg 409
Cdd:PRK13484  313 VksGKKDKYNHWDLNYESRKPEITNTIIDAKVtAFLPENVLTIGGQ-FQHAELRDDSATGKKTTETQSVSIKQKAVFIE- 390

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 410 NELELTERLWLSSGLSLVNirrdvdvnfsdrantspypQHYKYDNWSlaPRLGLRYFLTPDIQLFGNVSRSIDPPSAWSI 489
Cdd:PRK13484  391 NEYAATDSLALTGGLRLDN-------------------HEIYGSYWN--PRLYAVYNLTDNLTLKGGIAKAFRAPSIREV 449

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 490 SPS-------GPTNNYA-KTLVEQKGNTVEIGIRGARGP-LSGSLALYRSWLHDELLNVEIiparGNSPAVTSTS----- 555
Cdd:PRK13484  450 SPGfgtltqgGASIMYGnRDLKPETSVTEEIGIIYSNDSgFSASATLFNTDFKNKLTSYDI----GTKDPVTGLNtfiyd 525

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 556 NASATIHQGVEAGLD---AELWRgvrgdtlvLRQAYTFNDFYYRNDDE-FGANELPG-----LPRHIYQAELKYQH--AS 624
Cdd:PRK13484  526 NVGEANIRGVELATQipvYDKWH--------VSANYTFTDSRRKSDDEsLNGKSLKGeplerTPRHAANAKLEWDYtqDI 597


                  ....
gi 2495644662 625 GFYA 628
Cdd:PRK13484  598 TFYS 601
PRK14050 PRK14050
TonB-dependent siderophore receptor;
19-262 1.66e-05

TonB-dependent siderophore receptor;


Pssm-ID: 237595 [Multi-domain]  Cd Length: 728  Bit Score: 48.26  E-value: 1.66e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662  19 LWMAVGIGSLMMAAGQGASAAEPAsekeqRLETVVVRGEQK-----------------TEAQKAKVKLEEVAGGTSLVDN 81
Cdd:PRK14050   14 LAAGVALAALVLSGLVAAQEGNTT-----QLETIVVEGGNAasatatgpvdgyvakatATGSKTDTPITEIPQSVSVVGR 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662  82 AEVE-KGRSSTLEDVLAFQPGVIAQAAGG-NDAIKISIRGSGAnASPGYFregtkflFDGLAL--TGPGGTpyeLLEMSG 157
Cdd:PRK14050   89 QEMDdRGVTNKVDEALRYTPGVLSQPFGTdGDTDWFYIRGFDA-TQTGVF-------LDGLNLfsYGFGGF---QIDPFM 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 158 VNYTEVLRGANAFDYTALSLGGAINMV-----------THTGHSSPGN-YARFEAGSfgwrkqQLSTGGVVddaDYYISL 225
Cdd:PRK14050  158 LERVEVLKGPASVLYGGSNPGGIVNMVskrpldeplyyTEIGINSYGNaFTGFDVGD------KLSDDGTV---RYRVTG 228

                         250       260       270
                  ....*....|....*....|....*....|....*..
gi 2495644662 226 SNSEREGYQDYTfNKAKGVVSNfGYRFSPKLDTRLIV 262
Cdd:PRK14050  229 KVAGGDNYSDYS-EDLRGFIMP-QITYAPDDATSLTV 263
PRK09840 PRK09840
catecholate siderophore receptor Fiu; Provisional
 454-685 3.63e-05

catecholate siderophore receptor Fiu; Provisional


Pssm-ID: 182105 [Multi-domain]  Cd Length: 761  Bit Score: 47.11  E-value: 3.63e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 454 NWslapRLGLRYFLTPDIQLFGNVSRSIDPP--SAWSISPSGPTNNYAKTLVE-QKGNTVEIGIR--GARGPLSGSLALY 528
Cdd:PRK09840  515 NW----KAGALYKLTENGNVYINYAVSQQPPggSNFALAQSGSGNSANRTDFKpQKANTSEIGTKwqVLDKRLLLTAALF 590

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 529 RSwlhdELLNvEIIparGNSpaVTSTSNASATIHQGVEAGLDAEL---WRGVRG----DTLVLRQAYTFNDfyyrnddef 601
Cdd:PRK09840  591 RT----DIEN-EVE---QND--DGTYSQYGKKRVEGYELSVAGNItpaWQVIAGytqqKATVKNGKDVAQD--------- 651

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 602 GANELPGLPRHIYQAELKYQHASGFYAGVDVRTASSTPVDYANSFQAPSYT----VFGAKLGYeepgqRWQVFLDLR--- 674
Cdd:PRK09840  652 GSSSLPYTPEHAFTLWSQYQATDDLSVGGGARYIGSMHRGSDGAVGTPAFTegywVADAKLGY-----RVNRNLDLQlnv 726

                         250
                  ....*....|..
gi 2495644662 675 -NLTDEHYATTI 685
Cdd:PRK09840  727 yNLFDTDYVASI 738
PRK10064 PRK10064
catecholate siderophore receptor CirA; Provisional
 23-674 2.34e-04

catecholate siderophore receptor CirA; Provisional


Pssm-ID: 236646 [Multi-domain]  Cd Length: 663  Bit Score: 44.49  E-value: 2.34e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662  23 VGIGSLMMAAgqgASAAEPASEKEQRLETVVVrgeqktEAQKAKVKLEEVAGGTSLVDNAEVEKGRSSTLEDVLAFQPGV 102
Cdd:PRK10064    7 FVRVGLCASA---ISCAWPVLAVDDDGETMVV------TASAVEQNLKDAPASISVITQEDLQRKPVQNLKDVLKEVPGV 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 103 IAQAAGGNDAiKISIRGSGanaspgyfREGTKFLFDGLALTGPG----GTPYEL--LEMSGVNYTEVLRGANAFDYTALS 176
Cdd:PRK10064   78 QLTNEGDNRK-GVSIRGLD--------SSYTLILIDGKRVNSRNavfrHNDFDLnwIPVDAIERIEVVRGPMSSLYGSDA 148

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 177 LGGAINMVTHtghsspgnyarfeagsfgwRKQQLSTGGVVddADYYIslsnseregyQDYtfnKAKGVVSNFGYRFS-PK 255
Cdd:PRK10064  149 LGGVVNIITK-------------------KIGQKWHGTVT--VDTTI----------QEH---RDRGDTYNGQFFTSgPL 194

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 256 LDTRLIVRYReqyhenASTLTRAqlKDDPSQPNPTTVAQ----RGDSTKNGSIwvgsKTTYTLDDDSQVELGLVYHNY-- 329
Cdd:PRK10064  195 IDGVLGMKAY------GSLAKRE--KDDPQNSTTTDTGEtpriEGFTSRDGNV----EFAWTPNQNHDFTAGYGFDRQdr 262

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 330 ------RQILGKKSPVIPNHWQWRDLNSSLRYL--RSDRLFGLQSNTTLSFSNTLHDR--------AEVKTYDGVSR--K 391
Cdd:PRK10064  263 dsdsldKNRLERQNYSLSHNGRWDYGNSELKYYgeKVENKNPGNSSPITSESNSIDGKytlpltaiNQFLTFGGEWRhdK 342

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 392 LLKETNYSGSFDTVFAAG-------NELELTERLWLSSGlslvnIRRDvdvnfsdrantspypQHYKY-DNWSlaPRLGL 463
Cdd:PRK10064  343 LSDAVNLTGGTSSKTSASqyalfveDEWRIFEPLALTTG-----VRMD---------------DHETYgDHWS--PRAYL 400

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 464 RYFLTPDIQLFGNVSRSIDPPSAWSISPSGPTNNY--------AKTLVEQKGNTVEIGIR--GARGPLSG---SLALYRS 530
Cdd:PRK10064  401 VYNATDTVTVKGGWATAFKAPSLLQLSPDWTSNSCrgackivgSPDLKPETSESWELGLYymGEEGWLEGvesSVTVFRN 480

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 531 WLHDEL-----LNVEIIP-----------ARGNSPAVTSTSNASATIHQGVEAGLDAELwrgvrGDTLVLRQAYTFNDfy 594
Cdd:PRK10064  481 DVDDRIsisrtSDVNAAPgyqnfvgfetnGRGRRVPVFRYYNVNKARIQGVETELKIPF-----NDEWKLSLNYTYND-- 553

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 595 yRNDDEFGANE-LPGLPRHIYQAELKYQHA---------SGFYAGV--DVRTASSTPVDYA-----NSFQAPSYTVFGAK 657
Cdd:PRK10064  554 -GRDVSNGENKpLSDLPFHTANGTLDWKPLaledwsfyvSGNYTGQkrADSATAKTPGGYTiwntgAAWQVTKDVKLRAG 632

                         730       740       750
                  ....*....|....*....|....*....|
gi 2495644662 658 L-------------GYEEPGQRWQVFLDLR 674
Cdd:PRK10064  633 VlnlgdkdlsrddySYNEDGRRYFMAVDYR 662
PRK10044 PRK10044
ferrichrome outer membrane transporter; Provisional
 27-222 8.33e-04

ferrichrome outer membrane transporter; Provisional


Pssm-ID: 236643 [Multi-domain]  Cd Length: 727  Bit Score: 42.82  E-value: 8.33e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662  27 SLMMAAGQGASAAEPASEKEQRLETVVVRGEQKTE-----------------AQKAKVKLEEVAGGTSLVDNAEVEKGRS 89
Cdd:PRK10044   17 AVVVATAVSGMSVYAQAAVEPKEETITVTAAPAPQesawgpaatiaakrsatGTKTDTPIEKTPQSISVVTAEEMALHQP 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662  90 STLEDVLAFQPGVIAQAAGGNDAIK-ISIRGSGANASpgyfreGTKFLFDGLALTGPGGT-----PYeLLEMSgvnytEV 163
Cdd:PRK10044   97 KSVKEALSYTPGVSVGTRGASNTYDhLIIRGFAASGQ------SQNNYLDGLKLQGNFYNdavidPY-MLERA-----EL 164

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2495644662 164 LRGANAFDYTALSLGGAINMVTHTGHSSPGNYARFEAGSFGWRKQQLSTGGVVDDADYY 222
Cdd:PRK10044  165 MRGPVSVLYGKSNPGGLLNMVSKRPTTEPLKEVQFKMGTDNLFQTGFDFSDALDDDGVY 223
PRK13513 PRK13513
ligand-gated channel protein;
25-660 3.72e-03

ligand-gated channel protein;


Pssm-ID: 184104 [Multi-domain]  Cd Length: 659  Bit Score: 40.52  E-value: 3.72e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662  25 IGSLMMAAGQGASAAEPASEKEQRLETVVVrgeqktEAQKAKVKLEEVAGGTSLVDNAEVEKGRSSTLEDVLAFQPGVIA 104
Cdd:PRK13513   11 AALVIAAAISSQAYAAEKTNTATPTDTMVV------TASGFQQRIQDAPASISVVTREQLENKAYRDVTDALKDVPGVVV 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 105 qaAGGNDAIKISIRGsganASPGYfregTKFLFDGLALTGPGGTPYE---------LLEMSGVNYTEVLRGANAFDYTAL 175
Cdd:PRK13513   85 --TGGGSTSDISIRG----MAAKY----TLILVDGKRVDTRSTRPNSdgsgieqgwLPPLAAIERIEVVRGPMSSLYGSD 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 176 SLGGAINMVThtghsspgnyarfeagsfgwRKQQLSTGGVVdDADYYISLSNSEREGYQDYTFNKAKGVVSNFGYR---- 251
Cdd:PRK13513  155 AMGGVINIIT--------------------RKVQKEWHGSL-RADATLQEDSKSGDIFQTNAYASGPLIDGLLGLKvsgl 213

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 252 FSPKLDTRLIVRYREQYHENAS-TLTRA-------------QLKDDPSQPNPTTVAQRGDS-----------TKNGSIWV 306
Cdd:PRK13513  214 LSHRSEDKIIDGYNEQRMRNGTaTFSLTpddnnefdfeigrYVQDRNSTPGRTLALNGTNSdtqydrnnyaiTHNGYYDF 293

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 307 GSKTTYTLDDDSqvelglvyHNyrqilgkkspviPNhwqwRDLNSSLRYLRSDRLFGLQSNtTLSFS-----NTLHDRA- 380
Cdd:PRK13513  294 GNSTSYIQRDET--------RN------------PS----RQMKSVDTIFNTQTSFLLDDH-TLSLGgqyryEELYDKGn 348

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 381 EVKTYDGVSrkllKETNYSGSfdtVFAAgNELELTERLWLSSGlslvnIRRDVDVNFSdrantspypqhykyDNWSlaPR 460
Cdd:PRK13513  349 QLPSASDLN----KLTRWSWA---LFAE-DEWQMTNDFALTGG-----IRMDQDQNYG--------------THWT--PR 399

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 461 LGLRYFLTPDIQLFGNVS---RSID---PPSAWSISPSGPTNNYA----KTLVEQKGNTVEIGIR-GARGPLSGSLALYR 529
Cdd:PRK13513  400 LYGVWHLADQWTLKGGVStgyRSPDlrqATDNWGQLTGGGGLPALilgnSDLKPEKSISQEIGILwDNQENLNASVTLFN 479

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 530 SWLHDELLNVEIIPARGNSPAVTSTSNASATIHQGVEagLDAELWRGVRG-------DTLVLRQAYTFNDFYYRNDDeFG 602
Cdd:PRK13513  480 TDFKDKITEVRNCDTTNTDGQCVFNGINYDFISDRIN--VDKANMRGVEAtfnwdinQAWSLATNYTFTQSEQKSGA-FA 556

                         650       660       670       680       690       700
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2495644662 603 ANELPGLPRHIYQAELKYQ--HASGFYAGVDVRTASStpvDYAN--SFQ--APSYTVFGAKLGY 660
Cdd:PRK13513  557 GQPLNQMPKHMANATLNWQttEDFATWIRINYRGKTS---EYLNrtSMGsgTPSYTFVDLGASY 617
btuB PRK10641
TonB-dependent vitamin B12 receptor BtuB;
76-187 6.41e-03

TonB-dependent vitamin B12 receptor BtuB;


Pssm-ID: 236730 [Multi-domain]  Cd Length: 614  Bit Score: 39.98  E-value: 6.41e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662  76 TSLVDNAEVEKGRSSTLEDVLAFQPGV-IAQAAGGNDAIKISIRGSGANAspgyfregTKFLFDGLALTGPG--GTP-YE 151
Cdd:PRK10641   46 TTVVTRDDIDRWQSKSVNDVLRRLPGVdIAQNGGLGQLSSLFIRGTNSSH--------VLVLIDGVRLNQAGisGSAdLS 117

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 2495644662 152 LLEMSGVNYTEVLRGANAFDYTALSLGGAINMVTHT 187
Cdd:PRK10641  118 QIPISLVQRIEYIRGPRSAVYGSDAIGGVVNIITTR 153
PRK14049 PRK14049
ferrioxamine B receptor precursor protein; Provisional
 31-262 7.99e-03

ferrioxamine B receptor precursor protein; Provisional


Pssm-ID: 172541 [Multi-domain]  Cd Length: 726  Bit Score: 39.50  E-value: 7.99e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662  31 AAGQGASAAEPASEKEQRLETVVVRGEQ-----------KTEAQKAKVK--LEEVAGGTSLVDNAEVEKGRSSTLEDVLA 97
Cdd:PRK14049   25 AQAQDAGQESVSNEASTALETLVVNGGSggvitadgyvaTSSATGAKVDtpFLETPQSISSVTEQQLKDRNPQTLLETLA 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662  98 FQPGVIAQAAGGN---DAIkiSIRGSGANASpGYFREGtkflfdglaLTGPGGT-------PYellemsGVNYTEVLRGA 167
Cdd:PRK14049  105 YTPGARVGAFGFDprfDAF--FVRGFDVTYT-GVFRDN---------LRQPGASssifktePY------GLEGVSILRGP 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495644662 168 NAFDYTALSLGGAINMVTHTGHSSPGNYARFEAGSFGWRKQQLSTGGVVDDAD--YY-----ISLSNSEREGYQDYTFNK 240
Cdd:PRK14049  167 SSALYGASGAGGLFNLITKRPTEEPLREVQVQYGTNNRYQGQFDFSGPVNETDpvYYrltglLRDADTEQVGVPDDRAYI 246

                         250       260
                  ....*....|....*....|..
gi 2495644662 241 AKgvvsnfGYRFSPKLDTRLIV 262
Cdd:PRK14049  247 AP------AFTWKPDEDTRLTV 262
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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