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Conserved domains on  [gi|2495847060|ref|WP_280063102|]
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MULTISPECIES: twin-arginine translocase TatA/TatE family subunit [Empedobacter]

Protein Classification

Sec-independent protein translocase family protein( domain architecture ID 241)

Sec-independent protein translocase family protein such as Sec-independent protein translocase proteins TatA and TatB, which are part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes

Gene Ontology:  GO:0033281|GO:0043953

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TatA_B_E super family cl00788
mttA/Hcf106 family; Members of this protein family are involved in a sec independent ...
 25-91 3.64e-08

mttA/Hcf106 family; Members of this protein family are involved in a sec independent translocation mechanism. This pathway has been called the DeltapH pathway in chloroplasts. Members of this family in E.coli are involved in export of redox proteins with a "twin arginine" leader motif.


The actual alignment was detected with superfamily member PRK14857:

Pssm-ID: 445098  Cd Length: 90  Bit Score: 48.95  E-value: 3.64e-08
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2495847060  25 VIFGPDKIPEIARGLGTAVRKLKEASE----DIKQEIMNPVQDVDPTKEIQNtiKELNPMNEVKDSFAKIN 91
Cdd:PRK14857   20 LVFGPKKLPEIGRSLGKTLKGFQEASKefenEIKREMAEPEQEVKAPAELES--NQTNEANQEQVDAENSP 88
 
Name Accession Description Interval E-value
tatA PRK14857
TatA/E family twin arginine-targeting protein translocase;
25-91 3.64e-08

TatA/E family twin arginine-targeting protein translocase;


Pssm-ID: 184859  Cd Length: 90  Bit Score: 48.95  E-value: 3.64e-08
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2495847060  25 VIFGPDKIPEIARGLGTAVRKLKEASE----DIKQEIMNPVQDVDPTKEIQNtiKELNPMNEVKDSFAKIN 91
Cdd:PRK14857   20 LVFGPKKLPEIGRSLGKTLKGFQEASKefenEIKREMAEPEQEVKAPAELES--NQTNEANQEQVDAENSP 88
TatA COG1826
Twin-arginine protein secretion pathway components TatA and TatB [Intracellular trafficking, ...
 27-73 1.02e-07

Twin-arginine protein secretion pathway components TatA and TatB [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 441431 [Multi-domain]  Cd Length: 72  Bit Score: 47.24  E-value: 1.02e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 2495847060  27 FGPDKIPEIARGLGTAVRKLKEASEDIKQEIMNPVQDVDPTKEIQNT 73
Cdd:COG1826    20 FGPKKLPELARSLGKAIREFKKAANEVKEELDEELKEEELRKSEKEA 66
TatA_B_E pfam02416
mttA/Hcf106 family; Members of this protein family are involved in a sec independent ...
 27-63 1.97e-06

mttA/Hcf106 family; Members of this protein family are involved in a sec independent translocation mechanism. This pathway has been called the DeltapH pathway in chloroplasts. Members of this family in E.coli are involved in export of redox proteins with a "twin arginine" leader motif.


Pssm-ID: 426762  Cd Length: 53  Bit Score: 43.06  E-value: 1.97e-06
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 2495847060  27 FGPDKIPEIARGLGTAVRKLKEASEDIKQEIMNPVQD 63
Cdd:pfam02416  17 FGPKKLPELGRALGKTLREFKKATKELEEEDEKEAQE 53
tatAE TIGR01411
twin arginine-targeting protein translocase, TatA/E family; This model distinguishes TatA/E ...
 27-56 2.68e-05

twin arginine-targeting protein translocase, TatA/E family; This model distinguishes TatA/E from the related TatB, but does not distinguish TatA from TatE. The Tat (twin-arginine translocation) system is a Sec-independent exporter for folded proteins, often with a redox cofactor already bound, across the bacterial inner membrane. Functionally equivalent systems are found in the chloroplast and some in archaeal species. The signal peptide recognized by the Tat system is modeled by TIGR01409. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 273605 [Multi-domain]  Cd Length: 47  Bit Score: 39.90  E-value: 2.68e-05
                          10        20        30
                  ....*....|....*....|....*....|
gi 2495847060  27 FGPDKIPEIARGLGTAVRKLKEASEDIKQE 56
Cdd:TIGR01411  18 FGAKKLPELGRDLGKAIKEFKKALKEEEDE 47
 
Name Accession Description Interval E-value
tatA PRK14857
TatA/E family twin arginine-targeting protein translocase;
25-91 3.64e-08

TatA/E family twin arginine-targeting protein translocase;


Pssm-ID: 184859  Cd Length: 90  Bit Score: 48.95  E-value: 3.64e-08
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2495847060  25 VIFGPDKIPEIARGLGTAVRKLKEASE----DIKQEIMNPVQDVDPTKEIQNtiKELNPMNEVKDSFAKIN 91
Cdd:PRK14857   20 LVFGPKKLPEIGRSLGKTLKGFQEASKefenEIKREMAEPEQEVKAPAELES--NQTNEANQEQVDAENSP 88
TatA COG1826
Twin-arginine protein secretion pathway components TatA and TatB [Intracellular trafficking, ...
 27-73 1.02e-07

Twin-arginine protein secretion pathway components TatA and TatB [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 441431 [Multi-domain]  Cd Length: 72  Bit Score: 47.24  E-value: 1.02e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 2495847060  27 FGPDKIPEIARGLGTAVRKLKEASEDIKQEIMNPVQDVDPTKEIQNT 73
Cdd:COG1826    20 FGPKKLPELARSLGKAIREFKKAANEVKEELDEELKEEELRKSEKEA 66
PRK01371 PRK01371
Sec-independent protein translocase protein TatB;
27-115 1.82e-06

Sec-independent protein translocase protein TatB;


Pssm-ID: 179287 [Multi-domain]  Cd Length: 137  Bit Score: 45.47  E-value: 1.82e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495847060  27 FGPDKIPEIARGLGTAVRKLKE----ASEDIKQEIMNPVQDVDPTkeiqntikELNPMNEVKDSFakinpMEDFQKSFDE 102
Cdd:PRK01371   20 FGPDKLPKAARDAGRTLRQLREmannARNDLRSELGPEFADLDLR--------DLNPKTFVRKHL-----LEDLDDDIDE 86

                          90
                  ....*....|...
gi 2495847060 103 VRNPVDEMHQAIH 115
Cdd:PRK01371   87 IKLGLKTVRSGLD 99
TatA_B_E pfam02416
mttA/Hcf106 family; Members of this protein family are involved in a sec independent ...
 27-63 1.97e-06

mttA/Hcf106 family; Members of this protein family are involved in a sec independent translocation mechanism. This pathway has been called the DeltapH pathway in chloroplasts. Members of this family in E.coli are involved in export of redox proteins with a "twin arginine" leader motif.


Pssm-ID: 426762  Cd Length: 53  Bit Score: 43.06  E-value: 1.97e-06
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 2495847060  27 FGPDKIPEIARGLGTAVRKLKEASEDIKQEIMNPVQD 63
Cdd:pfam02416  17 FGPKKLPELGRALGKTLREFKKATKELEEEDEKEAQE 53
tatAE TIGR01411
twin arginine-targeting protein translocase, TatA/E family; This model distinguishes TatA/E ...
 27-56 2.68e-05

twin arginine-targeting protein translocase, TatA/E family; This model distinguishes TatA/E from the related TatB, but does not distinguish TatA from TatE. The Tat (twin-arginine translocation) system is a Sec-independent exporter for folded proteins, often with a redox cofactor already bound, across the bacterial inner membrane. Functionally equivalent systems are found in the chloroplast and some in archaeal species. The signal peptide recognized by the Tat system is modeled by TIGR01409. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 273605 [Multi-domain]  Cd Length: 47  Bit Score: 39.90  E-value: 2.68e-05
                          10        20        30
                  ....*....|....*....|....*....|
gi 2495847060  27 FGPDKIPEIARGLGTAVRKLKEASEDIKQE 56
Cdd:TIGR01411  18 FGAKKLPELGRDLGKAIKEFKKALKEEEDE 47
tatA PRK14861
twin arginine translocase protein A; Provisional
 27-56 1.18e-03

twin arginine translocase protein A; Provisional


Pssm-ID: 237837  Cd Length: 61  Bit Score: 35.72  E-value: 1.18e-03
                          10        20        30
                  ....*....|....*....|....*....|
gi 2495847060  27 FGPDKIPEIARGLGTAVRKLKEASEDIKQE 56
Cdd:PRK14861   21 FGPKKLPELGKALGKTLREFKKATKELTDD 50
tatA PRK14858
twin arginine translocase protein A; Provisional
 28-76 1.28e-03

twin arginine translocase protein A; Provisional


Pssm-ID: 184860  Cd Length: 108  Bit Score: 36.77  E-value: 1.28e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2495847060  28 GPDKIPEIARGLGTAVRKLKEASEDIKQEIMNPVQDVD---PTKEIQNTIKE 76
Cdd:PRK14858   21 GPQKLPDLARSLGRGLAEFKKATDDFKQSMQEESRTAEekeKAEKLAETKKE 72
tatA PRK14859
twin arginine translocase protein A; Provisional
 27-68 1.67e-03

twin arginine translocase protein A; Provisional


Pssm-ID: 184861  Cd Length: 63  Bit Score: 35.47  E-value: 1.67e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 2495847060  27 FGPDKIPEIARGLGTAVRKLKEASEDiKQEImnpvqDVDPTK 68
Cdd:PRK14859   20 FGAGKLPEIGGGLGKSIKNFKKATSE-KEEI-----EIKPTK 55
tatA PRK14860
twin arginine translocase protein A; Provisional
 27-52 6.57e-03

twin arginine translocase protein A; Provisional


Pssm-ID: 184862  Cd Length: 64  Bit Score: 33.94  E-value: 6.57e-03
                          10        20
                  ....*....|....*....|....*.
gi 2495847060  27 FGPDKIPEIARGLGTAVRKLKEASED 52
Cdd:PRK14860   20 FGPAKLPQLGQALGGAIRNFKKASNE 45
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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