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Conserved domains on  [gi|2506233547|ref|WP_282742686|]
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ABC transporter ATP-binding protein [Olsenella uli]

Protein Classification

ABC transporter ATP-binding protein( domain architecture ID 11437844)

ABC transporter ATP-binding protein is the ATPase catalytic subunit of an ATP transporter complex responsible for coupling the energy of ATP hydrolysis to the import of one or more from a variety of substrates

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PhnK COG1101
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
1-264 1.91e-165

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


:

Pssm-ID: 440718 [Multi-domain]  Cd Length: 264  Bit Score: 458.40  E-value: 1.91e-165
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   1 MLVLKGVTKTFNKSTVNEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRAT 80
Cdd:COG1101     1 MLELKNLSKTFNPGTVNEKRALDGLNLTIEEGDFVTVIGSNGAGKSTLLNAIAGSLPPDSGSILIDGKDVTKLPEYKRAK 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  81 DLGRVFQDPMRGTAADMQIVENLALAARRGESRGLSWGITRDERASYRERLAELDLGLEERLTSKVGLLSGGQRQALTLL 160
Cdd:COG1101    81 YIGRVFQDPMMGTAPSMTIEENLALAYRRGKRRGLRRGLTKKRRELFRELLATLGLGLENRLDTKVGLLSGGQRQALSLL 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 161 MAILKKPKLLLLDEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNVIFDARDDEKRRLR 240
Cdd:COG1101   161 MATLTKPKLLLLDEHTAALDPKTAALVLELTEKIVEENNLTTLMVTHNMEQALDYGNRLIMMHEGRIILDVSGEEKKKLT 240
                         250       260
                  ....*....|....*....|....
gi 2506233547 241 VHDLLQKFEEASGGELANDRMLLS 264
Cdd:COG1101   241 VEDLLELFEEIRGEELADDRLLLG 264
 
Name Accession Description Interval E-value
PhnK COG1101
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
1-264 1.91e-165

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 440718 [Multi-domain]  Cd Length: 264  Bit Score: 458.40  E-value: 1.91e-165
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   1 MLVLKGVTKTFNKSTVNEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRAT 80
Cdd:COG1101     1 MLELKNLSKTFNPGTVNEKRALDGLNLTIEEGDFVTVIGSNGAGKSTLLNAIAGSLPPDSGSILIDGKDVTKLPEYKRAK 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  81 DLGRVFQDPMRGTAADMQIVENLALAARRGESRGLSWGITRDERASYRERLAELDLGLEERLTSKVGLLSGGQRQALTLL 160
Cdd:COG1101    81 YIGRVFQDPMMGTAPSMTIEENLALAYRRGKRRGLRRGLTKKRRELFRELLATLGLGLENRLDTKVGLLSGGQRQALSLL 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 161 MAILKKPKLLLLDEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNVIFDARDDEKRRLR 240
Cdd:COG1101   161 MATLTKPKLLLLDEHTAALDPKTAALVLELTEKIVEENNLTTLMVTHNMEQALDYGNRLIMMHEGRIILDVSGEEKKKLT 240
                         250       260
                  ....*....|....*....|....
gi 2506233547 241 VHDLLQKFEEASGGELANDRMLLS 264
Cdd:COG1101   241 VEDLLELFEEIRGEELADDRLLLG 264
ABC_MJ0796_LolCDE_FtsE cd03255
ATP-binding cassette domain of the transporters involved in export of lipoprotein and ...
2-227 6.01e-47

ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.


Pssm-ID: 213222 [Multi-domain]  Cd Length: 218  Bit Score: 155.73  E-value: 6.01e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   2 LVLKGVTKTFnKSTVNEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHR---- 77
Cdd:cd03255     1 IELKNLSKTY-GGGGEKVQALKGVSLSIEKGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVRVDGTDISKLSEKElaaf 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  78 RATDLGRVFQD----PmrgtaaDMQIVENLALAARrgesrglswgITRDERASYRERLAEL--DLGLEERLTSKVGLLSG 151
Cdd:cd03255    80 RRRHIGFVFQSfnllP------DLTALENVELPLL----------LAGVPKKERRERAEELleRVGLGDRLNHYPSELSG 143
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 152 GQRQ------ALT----LLMAilkkpkllllDEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAiRLGNRLIM 221
Cdd:cd03255   144 GQQQrvaiarALAndpkIILA----------DEPTGNLDSETGKEVMELLRELNKEAGTTIVVVTHDPELA-EYADRIIE 212

                  ....*.
gi 2506233547 222 MHEGNV 227
Cdd:cd03255   213 LRDGKI 218
ABC_phnC TIGR02315
phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of ...
1-231 1.72e-33

phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of phosphorus-containing organic compound with a stable direct C-P bond rather than a C-O-P linkage. A number of bacterial species have operons, typically about 14 genes in size, with genes for ATP-dependent transport of phosphonates, degradation, and regulation of the expression of the system. Members of this protein family are the ATP-binding cassette component of tripartite ABC transporters of phosphonates. [Transport and binding proteins, Anions]


Pssm-ID: 131368 [Multi-domain]  Cd Length: 243  Bit Score: 121.64  E-value: 1.72e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   1 MLVLKGVTKTFNkstvNEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSR-----LPE 75
Cdd:TIGR02315   1 MLEVENLSKVYP----NGKQALKNINLNINPGEFVAIIGPSGAGKSTLLRCINRLVEPSSGSILLEGTDITKlrgkkLRK 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  76 HRRATdlGRVFQDpmrgtaadMQIVENLA-----LAARRGESRGLSWGITRDERASYRERLAELD-LGLEERLTSKVGLL 149
Cdd:TIGR02315  77 LRRRI--GMIFQH--------YNLIERLTvlenvLHGRLGYKPTWRSLLGRFSEEDKERALSALErVGLADKAYQRADQL 146
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 150 SGGQRQALTLLMAILKKPKLLLLDEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNVIF 229
Cdd:TIGR02315 147 SGGQQQRVAIARALAQQPDLILADEPIASLDPKTSKQVMDYLKRINKEDGITVIINLHQVDLAKKYADRIVGLKAGEIVF 226

                  ..
gi 2506233547 230 DA 231
Cdd:TIGR02315 227 DG 228
glnQ PRK09493
glutamine ABC transporter ATP-binding protein GlnQ;
1-246 2.06e-31

glutamine ABC transporter ATP-binding protein GlnQ;


Pssm-ID: 181906 [Multi-domain]  Cd Length: 240  Bit Score: 116.35  E-value: 2.06e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   1 MLVLKGVTKTFNKSTVnekpaLTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDV--SRLPEHRR 78
Cdd:PRK09493    1 MIEFKNVSKHFGPTQV-----LHNIDLNIDQGEVVVIIGPSGSGKSTLLRCINKLEEITSGDLIVDGLKVndPKVDERLI 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  79 ATDLGRVFQD----PmrgtaaDMQIVENLALAARRgeSRGLSwgiTRDERASYRERLAELdlGLEERLTSKVGLLSGGQR 154
Cdd:PRK09493   76 RQEAGMVFQQfylfP------HLTALENVMFGPLR--VRGAS---KEEAEKQARELLAKV--GLAERAHHYPSELSGGQQ 142
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 155 QALTLLMAILKKPKLLLLDEHTAALDPKTASKVLALTERLvGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNVIFDARDD 234
Cdd:PRK09493  143 QRVAIARALAVKPKLMLFDEPTSALDPELRHEVLKVMQDL-AEEGMTMVIVTHEIGFAEKVASRLIFIDKGRIAEDGDPQ 221
                         250
                  ....*....|....*...
gi 2506233547 235 E------KRRLRvhDLLQ 246
Cdd:PRK09493  222 VliknppSQRLQ--EFLQ 237
AztA NF040873
zinc ABC transporter ATP-binding protein AztA;
20-214 2.24e-21

zinc ABC transporter ATP-binding protein AztA;


Pssm-ID: 468810 [Multi-domain]  Cd Length: 191  Bit Score: 88.44  E-value: 2.24e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  20 PALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQV-ILDGRDVSRLPEHrraTDLGRVFQDPMRGTAAdmq 98
Cdd:NF040873    6 PVLHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLRPTSGTVrRAGGARVAYVPQR---SEVPDSLPLTVRDLVA--- 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  99 ivenLALAARRGESRGLswgiTRDERASYRERLAELDL-GLEERltsKVGLLSGGQRQALTLLMAILKKPKLLLLDEHTA 177
Cdd:NF040873   80 ----MGRWARRGLWRRL----TRDDRAAVDDALERVGLaDLAGR---QLGELSGGQRQRALLAQGLAQEADLLLLDEPTT 148
                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 2506233547 178 ALDPKTASKVLALTERLVGEhGLTTLMVTHNMNDAIR 214
Cdd:NF040873  149 GLDAESRERIIALLAEEHAR-GATVVVVTHDLELVRR 184
ABC_tran pfam00005
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ...
22-163 2.26e-21

ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.


Pssm-ID: 394964 [Multi-domain]  Cd Length: 150  Bit Score: 87.32  E-value: 2.26e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  22 LTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRATDLGRVFQDPmrGTAADMQIVE 101
Cdd:pfam00005   1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQDLTDDERKSLRKEIGYVFQDP--QLFPRLTVRE 78
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2506233547 102 NLALAARrgeSRGLSWGITRDERASYRERLAELDLgLEERLTSKVGLLSGGQRQALTLLMAI 163
Cdd:pfam00005  79 NLRLGLL---LKGLSKREKDARAEEALEKLGLGDL-ADRPVGERPGTLSGGQRQRVAIARAL 136
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
4-228 9.48e-11

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 61.68  E-value: 9.48e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   4 LKGVTKTFNKSTvnekpALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRlPEHRRAT--- 80
Cdd:NF033858    4 LEGVSHRYGKTV-----ALDDVSLDIPAGCMVGLIGPDGVGKSSLLSLIAGARKIQQGRVEVLGGDMAD-ARHRRAVcpr 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  81 ------DLGR-------VFqdpmrgtaadmqivENLALAARrgesrgLsWGITRDERasyRERLAEL--DLGLEERLTSK 145
Cdd:NF033858   78 iaympqGLGKnlyptlsVF--------------ENLDFFGR------L-FGQDAAER---RRRIDELlrATGLAPFADRP 133
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 146 VGLLSGGQRQALTLLMAILKKPKLLLLDEHTAALDPKTASKVLALTERLVGEH-GLTTLMVTHNMNDAIRLgNRLIMMHE 224
Cdd:NF033858  134 AGKLSGGMKQKLGLCCALIHDPDLLILDEPTTGVDPLSRRQFWELIDRIRAERpGMSVLVATAYMEEAERF-DWLVAMDA 212

                  ....
gi 2506233547 225 GNVI 228
Cdd:NF033858  213 GRVL 216
40850658_otr NF000106
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
4-262 5.49e-09

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;


Pssm-ID: 411078 [Multi-domain]  Cd Length: 351  Bit Score: 55.90  E-value: 5.49e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   4 LKGVTKTFNkstvnEKPALTGVDLHLEPGDFVTVIGGNGAGKSTllnsiaGVFALDggqviLDGRDVSRLP-------EH 76
Cdd:NF000106   16 VRGLVKHFG-----EVKAVDGVDLDVREGTVLGVLGP*GAA**R------GALPAH-----V*GPDAGRRPwrf*twcAN 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  77 RRATDLGRVFQDPMR-GTAADMQIVENLALAARRGE-SRglswgitRDERASYRERLAELDLglEERLTSKVGLLSGGQR 154
Cdd:NF000106   80 RRALRRTIG*HRPVR*GRRESFSGRENLYMIGR*LDlSR-------KDARARADELLERFSL--TEAAGRAAAKYSGGMR 150
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 155 QALTLLMAILKKPKLLLLDEHTAALDPKTASKVLALTERLVGEhGLTTLMVTHNMNDAIRLGNRLIMMHEGNVIFDARDD 234
Cdd:NF000106  151 RRLDLAASMIGRPAVLYLDEPTTGLDPRTRNEVWDEVRSMVRD-GATVLLTTQYMEEAEQLAHELTVIDRGRVIADGKVD 229
                         250       260
                  ....*....|....*....|....*...
gi 2506233547 235 EkRRLRVHDLLQKFEEASGGELanDRML 262
Cdd:NF000106  230 E-LKTKVGGRTLQIRPAHAAEL--DRMV 254
GguA NF040905
sugar ABC transporter ATP-binding protein;
1-235 8.32e-08

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 52.48  E-value: 8.32e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   1 MLVLKGVTKTFnkstvnekP---ALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFAlDG---GQVILDGrDVSRLP 74
Cdd:NF040905    1 ILEMRGITKTF--------PgvkALDDVNLSVREGEIHALCGENGAGKSTLMKVLSGVYP-HGsyeGEILFDG-EVCRFK 70
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  75 EHRRATDLGRVF--QD----PMrgtaadMQIVENLALAARRGeSRGL-SWGITRdERAsyRERLAELdlGLEERLTSKVG 147
Cdd:NF040905   71 DIRDSEALGIVIihQElaliPY------LSIAENIFLGNERA-KRGViDWNETN-RRA--RELLAKV--GLDESPDTLVT 138
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 148 LLSGGQRQALTLLMAILKKPKLLLLDEHTAALDPKTASKVLALTERLvGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNV 227
Cdd:NF040905  139 DIGVGKQQLVEIAKALSKDVKLLILDEPTAALNEEDSAALLDLLLEL-KAQGITSIIISHKLNEIRRVADSITVLRDGRT 217
                         250
                  ....*....|
gi 2506233547 228 I--FDARDDE 235
Cdd:NF040905  218 IetLDCRADE 227
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
31-110 3.98e-04

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 39.66  E-value: 3.98e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   31 PGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRATDLGRVFQDPMRGTAADMQIVENLALAARRG 110
Cdd:smart00382   1 PGEVILIVGPPGSGKTTLARALARELGPPGGGVIYIDGEDILEEVLDQLLLIIVGGKKASGSGELRLRLALALARKLKPD 80
 
Name Accession Description Interval E-value
PhnK COG1101
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
1-264 1.91e-165

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 440718 [Multi-domain]  Cd Length: 264  Bit Score: 458.40  E-value: 1.91e-165
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   1 MLVLKGVTKTFNKSTVNEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRAT 80
Cdd:COG1101     1 MLELKNLSKTFNPGTVNEKRALDGLNLTIEEGDFVTVIGSNGAGKSTLLNAIAGSLPPDSGSILIDGKDVTKLPEYKRAK 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  81 DLGRVFQDPMRGTAADMQIVENLALAARRGESRGLSWGITRDERASYRERLAELDLGLEERLTSKVGLLSGGQRQALTLL 160
Cdd:COG1101    81 YIGRVFQDPMMGTAPSMTIEENLALAYRRGKRRGLRRGLTKKRRELFRELLATLGLGLENRLDTKVGLLSGGQRQALSLL 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 161 MAILKKPKLLLLDEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNVIFDARDDEKRRLR 240
Cdd:COG1101   161 MATLTKPKLLLLDEHTAALDPKTAALVLELTEKIVEENNLTTLMVTHNMEQALDYGNRLIMMHEGRIILDVSGEEKKKLT 240
                         250       260
                  ....*....|....*....|....
gi 2506233547 241 VHDLLQKFEEASGGELANDRMLLS 264
Cdd:COG1101   241 VEDLLELFEEIRGEELADDRLLLG 264
LolD COG1136
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];
1-228 4.52e-48

ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440751 [Multi-domain]  Cd Length: 227  Bit Score: 159.05  E-value: 4.52e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   1 MLVLKGVTKTFnKSTVNEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRA- 79
Cdd:COG1136     4 LLELRNLTKSY-GTGEGEVTALRGVSLSIEAGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVLIDGQDISSLSERELAr 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  80 ---TDLGRVFQD----PmrgtaaDMQIVENLALAARRGesrglswGITRDERasyRERLAEL--DLGLEERLTSKVGLLS 150
Cdd:COG1136    83 lrrRHIGFVFQFfnllP------ELTALENVALPLLLA-------GVSRKER---RERARELleRVGLGDRLDHRPSQLS 146
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 151 GGQRQ------AL----TLLMAilkkpkllllDEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMnDAIRLGNRLI 220
Cdd:COG1136   147 GGQQQrvaiarALvnrpKLILA----------DEPTGNLDSKTGEEVLELLRELNRELGTTIVMVTHDP-ELAARADRVI 215

                  ....*...
gi 2506233547 221 MMHEGNVI 228
Cdd:COG1136   216 RLRDGRIV 223
ABC_MJ0796_LolCDE_FtsE cd03255
ATP-binding cassette domain of the transporters involved in export of lipoprotein and ...
2-227 6.01e-47

ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.


Pssm-ID: 213222 [Multi-domain]  Cd Length: 218  Bit Score: 155.73  E-value: 6.01e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   2 LVLKGVTKTFnKSTVNEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHR---- 77
Cdd:cd03255     1 IELKNLSKTY-GGGGEKVQALKGVSLSIEKGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVRVDGTDISKLSEKElaaf 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  78 RATDLGRVFQD----PmrgtaaDMQIVENLALAARrgesrglswgITRDERASYRERLAEL--DLGLEERLTSKVGLLSG 151
Cdd:cd03255    80 RRRHIGFVFQSfnllP------DLTALENVELPLL----------LAGVPKKERRERAEELleRVGLGDRLNHYPSELSG 143
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 152 GQRQ------ALT----LLMAilkkpkllllDEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAiRLGNRLIM 221
Cdd:cd03255   144 GQQQrvaiarALAndpkIILA----------DEPTGNLDSETGKEVMELLRELNKEAGTTIVVVTHDPELA-EYADRIIE 212

                  ....*.
gi 2506233547 222 MHEGNV 227
Cdd:cd03255   213 LRDGKI 218
ABC_Mj1267_LivG_branched cd03219
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ...
2-238 8.53e-46

ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).


Pssm-ID: 213186 [Multi-domain]  Cd Length: 236  Bit Score: 153.36  E-value: 8.53e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   2 LVLKGVTKTFNKSTvnekpALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRAT- 80
Cdd:cd03219     1 LEVRGLTKRFGGLV-----ALDDVSFSVRPGEIHGLIGPNGAGKTTLFNLISGFLRPTSGSVLFDGEDITGLPPHEIARl 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  81 DLGRVFQDPmrGTAADMQIVENLALAARRGESRGLSWGITRDERASYRERLAEL--DLGLEERLTSKVGLLSGGQRQALT 158
Cdd:cd03219    76 GIGRTFQIP--RLFPELTVLENVMVAAQARTGSGLLLARARREEREARERAEELleRVGLADLADRPAGELSYGQQRRLE 153
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 159 LLMAILKKPKLLLLDEHTAALDPKTASKVLALTERLVgEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNVIFDARDDEKRR 238
Cdd:cd03219   154 IARALATDPKLLLLDEPAAGLNPEETEELAELIRELR-ERGITVLLVEHDMDVVMSLADRVTVLDQGRVIAEGTPDEVRN 232
PhnC COG3638
ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and ...
1-230 3.43e-45

ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 442855 [Multi-domain]  Cd Length: 249  Bit Score: 152.13  E-value: 3.43e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   1 MLVLKGVTKTFNkstvNEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLP-----E 75
Cdd:COG3638     2 MLELRNLSKRYP----GGTPALDDVSLEIERGEFVALIGPSGAGKSTLLRCLNGLVEPTSGEILVDGQDVTALRgralrR 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  76 HRRatDLGRVFQDPmrgtaadmQIVENL-----ALAARRGES---RGLSWGITRDERASYRERLAELdlGLEERLTSKVG 147
Cdd:COG3638    78 LRR--RIGMIFQQF--------NLVPRLsvltnVLAGRLGRTstwRSLLGLFPPEDRERALEALERV--GLADKAYQRAD 145
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 148 LLSGGQRQ------AL----TLLMAilkkpkllllDEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIRLGN 217
Cdd:COG3638   146 QLSGGQQQrvaiarALvqepKLILA----------DEPVASLDPKTARQVMDLLRRIAREDGITVVVNLHQVDLARRYAD 215
                         250
                  ....*....|...
gi 2506233547 218 RLIMMHEGNVIFD 230
Cdd:COG3638   216 RIIGLRDGRVVFD 228
ABC_Carb_Solutes_like cd03259
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ...
2-228 3.49e-45

ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213226 [Multi-domain]  Cd Length: 213  Bit Score: 151.13  E-value: 3.49e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   2 LVLKGVTKTFNkstvnEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRatD 81
Cdd:cd03259     1 LELKGLSKTYG-----SVRALDDLSLTVEPGEFLALLGPSGCGKTTLLRLIAGLERPDSGEILIDGRDVTGVPPERR--N 73
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  82 LGRVFQDPmrgtaA---DMQIVENLALAARRGesrglswGITRDERASYRERLAELdLGLEERLTSKVGLLSGGQRQALT 158
Cdd:cd03259    74 IGMVFQDY-----AlfpHLTVAENIAFGLKLR-------GVPKAEIRARVRELLEL-VGLEGLLNRYPHELSGGQQQRVA 140
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 159 LLMAILKKPKLLLLDEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNVI 228
Cdd:cd03259   141 LARALAREPSLLLLDEPLSALDAKLREELREELKELQRELGITTIYVTHDQEEALALADRIAVMNEGRIV 210
FepC COG1120
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ...
1-230 3.76e-41

ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];


Pssm-ID: 440737 [Multi-domain]  Cd Length: 254  Bit Score: 141.72  E-value: 3.76e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   1 MLVLKGVTKTFNKSTVnekpaLTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRAT 80
Cdd:COG1120     1 MLEAENLSVGYGGRPV-----LDDVSLSLPPGEVTALLGPNGSGKSTLLRALAGLLKPSSGEVLLDGRDLASLSRRELAR 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  81 DLGRVFQDPmrGTAADMQiVENLALAARRGESRGLSWGITRDERASyRERLAELDL-GLEERLtskVGLLSGGQRQ---- 155
Cdd:COG1120    76 RIAYVPQEP--PAPFGLT-VRELVALGRYPHLGLFGRPSAEDREAV-EEALERTGLeHLADRP---VDELSGGERQrvli 148
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 156 --ALT-----LLMailkkpkllllDEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNVI 228
Cdd:COG1120   149 arALAqepplLLL-----------DEPTSHLDLAHQLEVLELLRRLARERGRTVVMVLHDLNLAARYADRLVLLKDGRIV 217

                  ..
gi 2506233547 229 FD 230
Cdd:COG1120   218 AQ 219
TauB COG1116
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion ...
1-222 9.31e-41

ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440733 [Multi-domain]  Cd Length: 260  Bit Score: 141.00  E-value: 9.31e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   1 MLVLKGVTKTFNKSTvNEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRlPEHRRAT 80
Cdd:COG1116     7 ALELRGVSKRFPTGG-GGVTALDDVSLTVAAGEFVALVGPSGCGKSTLLRLIAGLEKPTSGEVLVDGKPVTG-PGPDRGV 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  81 dlgrVFQDPM----RgTAADmqiveNLALAARRGesrglswGITRDERasyRERLAE-LDL-GLEERLTSKVGLLSGGQR 154
Cdd:COG1116    85 ----VFQEPAllpwL-TVLD-----NVALGLELR-------GVPKAER---RERARElLELvGLAGFEDAYPHQLSGGMR 144
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2506233547 155 Q------ALT-----LLMailkkpkllllDEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIRLGNRLIMM 222
Cdd:COG1116   145 QrvaiarALAndpevLLM-----------DEPFGALDALTRERLQDELLRLWQETGKTVLFVTHDVDEAVFLADRVVVL 212
EcfA2 COG1122
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ...
2-230 1.11e-40

Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];


Pssm-ID: 440739 [Multi-domain]  Cd Length: 230  Bit Score: 139.78  E-value: 1.11e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   2 LVLKGVTKTFNkstvNEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRATD 81
Cdd:COG1122     1 IELENLSFSYP----GGTPALDDVSLSIEKGEFVAIIGPNGSGKSTLLRLLNGLLKPTSGEVLVDGKDITKKNLRELRRK 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  82 LGRVFQDPmrgtaaDMQIV-----ENLALAARRgesrglsWGITRDERasyRERLAEL--DLGLEERLTSKVGLLSGGQR 154
Cdd:COG1122    77 VGLVFQNP------DDQLFaptveEDVAFGPEN-------LGLPREEI---RERVEEAleLVGLEHLADRPPHELSGGQK 140
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 155 Q--AL---------TLLMailkkpkllllDEHTAALDPKTASKVLALTERLVGEhGLTTLMVTHNMNDAIRLGNRLIMMH 223
Cdd:COG1122   141 QrvAIagvlamepeVLVL-----------DEPTAGLDPRGRRELLELLKRLNKE-GKTVIIVTHDLDLVAELADRVIVLD 208

                  ....*..
gi 2506233547 224 EGNVIFD 230
Cdd:COG1122   209 DGRIVAD 215
PotA COG3842
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ...
1-228 1.48e-40

ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443052 [Multi-domain]  Cd Length: 353  Bit Score: 142.93  E-value: 1.48e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   1 MLVLKGVTKTFNkstvnEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRat 80
Cdd:COG3842     5 ALELENVSKRYG-----DVTALDDVSLSIEPGEFVALLGPSGCGKTTLLRMIAGFETPDSGRILLDGRDVTGLPPEKR-- 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  81 DLGRVFQD----PMrgtaadMQIVENLALAARRgesRGLSwgitRDERasyRERLAE-LDL-GLEERLTSKVGLLSGGQR 154
Cdd:COG3842    78 NVGMVFQDyalfPH------LTVAENVAFGLRM---RGVP----KAEI---RARVAElLELvGLEGLADRYPHQLSGGQQ 141
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 155 Q------ALT-----LLMailkkpkllllDEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIRLGNRLIMMH 223
Cdd:COG3842   142 QrvalarALApeprvLLL-----------DEPLSALDAKLREEMREELRRLQRELGITFIYVTHDQEEALALADRIAVMN 210

                  ....*
gi 2506233547 224 EGNVI 228
Cdd:COG3842   211 DGRIE 215
GsiA COG1123
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ...
1-235 1.99e-40

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440740 [Multi-domain]  Cd Length: 514  Bit Score: 145.82  E-value: 1.99e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   1 MLVLKGVTKTFNKSTVnekPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDG---GQVILDGRDVSRLPEHR 77
Cdd:COG1123     4 LLEVRDLSVRYPGGDV---PAVDGVSLTIAPGETVALVGESGSGKSTLALALMGLLPHGGrisGEVLLDGRDLLELSEAL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  78 RATDLGRVFQDPMrgTAADMQIVEN-LALAARRGesrglswGITRDERasyRERLAEL--DLGLEERLTSKVGLLSGGQR 154
Cdd:COG1123    81 RGRRIGMVFQDPM--TQLNPVTVGDqIAEALENL-------GLSRAEA---RARVLELleAVGLERRLDRYPHQLSGGQR 148
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 155 QALTLLMAILKKPKLLLLDEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNVIFDARDD 234
Cdd:COG1123   149 QRVAIAMALALDPDLLIADEPTTALDVTTQAEILDLLRELQRERGTTVLLITHDLGVVAEIADRVVVMDDGRIVEDGPPE 228

                  .
gi 2506233547 235 E 235
Cdd:COG1123   229 E 229
CcmA COG1131
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
2-230 6.71e-40

ABC-type multidrug transport system, ATPase component [Defense mechanisms];


Pssm-ID: 440746 [Multi-domain]  Cd Length: 236  Bit Score: 138.27  E-value: 6.71e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   2 LVLKGVTKTFNKstvneKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRAtD 81
Cdd:COG1131     1 IEVRGLTKRYGD-----KTALDGVSLTVEPGEIFGLLGPNGAGKTTTIRMLLGLLRPTSGEVRVLGEDVARDPAEVRR-R 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  82 LGRVFQDPmrGTAADMQIVENLALAARrgesrglSWGITRDERASYRERLAELdLGLEERLTSKVGLLSGGQRQALTLLM 161
Cdd:COG1131    75 IGYVPQEP--ALYPDLTVRENLRFFAR-------LYGLPRKEARERIDELLEL-FGLTDAADRKVGTLSGGMKQRLGLAL 144
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2506233547 162 AILKKPKLLLLDEHTAALDPKTASKVLALTERLVGEhGLTTLMVTHNMNDAIRLGNRLIMMHEGNVIFD 230
Cdd:COG1131   145 ALLHDPELLILDEPTSGLDPEARRELWELLRELAAE-GKTVLLSTHYLEEAERLCDRVAIIDKGRIVAD 212
GsiA COG1123
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ...
1-235 4.57e-39

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440740 [Multi-domain]  Cd Length: 514  Bit Score: 142.35  E-value: 4.57e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   1 MLVLKGVTKTFNKSTVNEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRR-- 78
Cdd:COG1123   260 LLEVRNLSKRYPVRGKGGVRAVDDVSLTLRRGETLGLVGESGSGKSTLARLLLGLLRPTSGSILFDGKDLTKLSRRSLre 339
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  79 -ATDLGRVFQDPMRGTAADMQIVENLALAARRgesRGLswgITRDERasyRERLAEL--DLGLEERLTSK-VGLLSGGQR 154
Cdd:COG1123   340 lRRRVQMVFQDPYSSLNPRMTVGDIIAEPLRL---HGL---LSRAER---RERVAELleRVGLPPDLADRyPHELSGGQR 410
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 155 Q------ALT----LLMAilkkpkllllDEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIRLGNRLIMMHE 224
Cdd:COG1123   411 QrvaiarALAlepkLLIL----------DEPTSALDVSVQAQILNLLRDLQRELGLTYLFISHDLAVVRYIADRVAVMYD 480
                         250
                  ....*....|.
gi 2506233547 225 GNVIFDARDDE 235
Cdd:COG1123   481 GRIVEDGPTEE 491
LivG COG0411
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid ...
1-230 1.98e-38

ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid transport and metabolism];


Pssm-ID: 440180 [Multi-domain]  Cd Length: 257  Bit Score: 134.78  E-value: 1.98e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   1 MLVLKGVTKTFNKSTvnekpALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRAT 80
Cdd:COG0411     4 LLEVRGLTKRFGGLV-----AVDDVSLEVERGEIVGLIGPNGAGKTTLFNLITGFYRPTSGRILFDGRDITGLPPHRIAR 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  81 D-LGRVFQDPmrGTAADMQIVENLALAARRGESRGL------SWGITRDERASYRERLAELD-LGLEERLTSKVGLLSGG 152
Cdd:COG0411    79 LgIARTFQNP--RLFPELTVLENVLVAAHARLGRGLlaallrLPRARREEREARERAEELLErVGLADRADEPAGNLSYG 156
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2506233547 153 QRQALTLLMAILKKPKLLLLDEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMnDAI-RLGNRLIMMHEGNVIFD 230
Cdd:COG0411   157 QQRRLEIARALATEPKLLLLDEPAAGLNPEETEELAELIRRLRDERGITILLIEHDM-DLVmGLADRIVVLDFGRVIAE 234
ABC_cobalt_CbiO_domain1 cd03225
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ...
3-225 4.75e-38

First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.


Pssm-ID: 213192 [Multi-domain]  Cd Length: 211  Bit Score: 132.59  E-value: 4.75e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   3 VLKGVTKTFNKStvnEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRATDL 82
Cdd:cd03225     1 ELKNLSFSYPDG---ARPALDDISLTIKKGEFVLIVGPNGSGKSTLLRLLNGLLGPTSGEVLVDGKDLTKLSLKELRRKV 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  83 GRVFQDPmrgtaaDMQIV-----ENLALAARRgesrglsWGITRDERASYRERLAELdLGLEERLTSKVGLLSGGQRQAL 157
Cdd:cd03225    78 GLVFQNP------DDQFFgptveEEVAFGLEN-------LGLPEEEIEERVEEALEL-VGLEGLRDRSPFTLSGGQKQRV 143
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2506233547 158 TLLMAILKKPKLLLLDEHTAALDPKTASKVLALTERLVGEhGLTTLMVTHNMNDAIRLGNRLIMMHEG 225
Cdd:cd03225   144 AIAGVLAMDPDILLLDEPTAGLDPAGRRELLELLKKLKAE-GKTIIIVTHDLDLLLELADRVIVLEDG 210
ABC_TM1139_LivF_branched cd03224
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ...
20-235 1.75e-37

ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.


Pssm-ID: 213191 [Multi-domain]  Cd Length: 222  Bit Score: 131.40  E-value: 1.75e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  20 PALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRATD-LGRVFQDpmRGTAADMQ 98
Cdd:cd03224    14 QILFGVSLTVPEGEIVALLGRNGAGKTTLLKTIMGLLPPRSGSIRFDGRDITGLPPHERARAgIGYVPEG--RRIFPELT 91
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  99 IVENLALAARRGESRGLSWGItrderasyrERLAELDLGLEERLTSKVGLLSGGQRQALTLLMAILKKPKLLLLDEHTAA 178
Cdd:cd03224    92 VEENLLLGAYARRRAKRKARL---------ERVYELFPRLKERRKQLAGTLSGGEQQMLAIARALMSRPKLLLLDEPSEG 162
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2506233547 179 LDPKTASKVLALTERLvGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNVIFDARDDE 235
Cdd:cd03224   163 LAPKIVEEIFEAIREL-RDEGVTILLVEQNARFALEIADRAYVLERGRVVLEGTAAE 218
FtsE COG2884
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];
1-232 6.41e-37

Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442130 [Multi-domain]  Cd Length: 223  Bit Score: 130.17  E-value: 6.41e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   1 MLVLKGVTKTFNkstvNEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRL-----PE 75
Cdd:COG2884     1 MIRFENVSKRYP----GGREALSDVSLEIEKGEFVFLTGPSGAGKSTLLKLLYGEERPTSGQVLVNGQDLSRLkrreiPY 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  76 HRRatDLGRVFQD----PmrgtaaDMQIVENLALAARrgesrglswgITRDERASYRERLAE-LDL-GLEERLTSKVGLL 149
Cdd:COG2884    77 LRR--RIGVVFQDfrllP------DRTVYENVALPLR----------VTGKSRKEIRRRVREvLDLvGLSDKAKALPHEL 138
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 150 SGGQRQ------AL----TLLMAilkkpkllllDEHTAALDPKTASKVLALTERLVgEHGLTTLMVTHNMNDAIRLGNRL 219
Cdd:COG2884   139 SGGEQQrvaiarALvnrpELLLA----------DEPTGNLDPETSWEIMELLEEIN-RRGTTVLIATHDLELVDRMPKRV 207
                         250
                  ....*....|...
gi 2506233547 220 IMMHEGNVIFDAR 232
Cdd:COG2884   208 LELEDGRLVRDEA 220
ThiQ COG3840
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];
1-235 1.11e-36

ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];


Pssm-ID: 443051 [Multi-domain]  Cd Length: 232  Bit Score: 129.49  E-value: 1.11e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   1 MLVLKGVTKTFNKSTVNekpaltgVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRAT 80
Cdd:COG3840     1 MLRLDDLTYRYGDFPLR-------FDLTIAAGERVAILGPSGAGKSTLLNLIAGFLPPDSGRILWNGQDLTALPPAERPV 73
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  81 DLgrVFQD----PmrgtaaDMQIVENLALaarrgesrGLSWG--ITRDERASYRERLAEldLGLEERLTSKVGLLSGGQR 154
Cdd:COG3840    74 SM--LFQEnnlfP------HLTVAQNIGL--------GLRPGlkLTAEQRAQVEQALER--VGLAGLLDRLPGQLSGGQR 135
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 155 QALTLLMAILKKPKLLLLDEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNVIFDARDD 234
Cdd:COG3840   136 QRVALARCLVRKRPILLLDEPFSALDPALRQEMLDLVDELCRERGLTVLMVTHDPEDAARIADRVLLVADGRIAADGPTA 215

                  .
gi 2506233547 235 E 235
Cdd:COG3840   216 A 216
ABC_PhnC_transporter cd03256
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ...
2-230 1.63e-36

ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213223 [Multi-domain]  Cd Length: 241  Bit Score: 129.61  E-value: 1.63e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   2 LVLKGVTKTFNkstvNEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDV-----SRLPEH 76
Cdd:cd03256     1 IEVENLSKTYP----NGKKALKDVSLSINPGEFVALIGPSGAGKSTLLRCLNGLVEPTSGSVLIDGTDInklkgKALRQL 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  77 RRatDLGRVFQDPmrgtaadmQIVENL--------ALAARRGESRGLSWGITRDERASYRERLAelDLGLEERLTSKVGL 148
Cdd:cd03256    77 RR--QIGMIFQQF--------NLIERLsvlenvlsGRLGRRSTWRSLFGLFPKEEKQRALAALE--RVGLLDKAYQRADQ 144
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 149 LSGGQRQALTLLMAILKKPKLLLLDEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNVI 228
Cdd:cd03256   145 LSGGQQQRVAIARALMQQPKLILADEPVASLDPASSRQVMDLLKRINREEGITVIVSLHQVDLAREYADRIVGLKDGRIV 224

                  ..
gi 2506233547 229 FD 230
Cdd:cd03256   225 FD 226
MlaF COG1127
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ...
1-230 2.48e-36

ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440744 [Multi-domain]  Cd Length: 241  Bit Score: 128.94  E-value: 2.48e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   1 MLVLKGVTKTFNKSTVnekpaLTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRA- 79
Cdd:COG1127     5 MIEVRNLTKSFGDRVV-----LDGVSLDVPRGEILAIIGGSGSGKSVLLKLIIGLLRPDSGEILVDGQDITGLSEKELYe 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  80 --TDLGRVFQDpmrgtAA---DMQIVENLALAARrgESRGLSWGITRdERAsyRERLAELDL-GLEERLTSKvglLSGGQ 153
Cdd:COG1127    80 lrRRIGMLFQG-----GAlfdSLTVFENVAFPLR--EHTDLSEAEIR-ELV--LEKLELVGLpGAADKMPSE---LSGGM 146
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 154 RQ------ALTL----LMAilkkpkllllDEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIRLGNRLIMMH 223
Cdd:COG1127   147 RKrvalarALALdpeiLLY----------DEPTAGLDPITSAVIDELIRELRDELGLTSVVVTHDLDSAFAIADRVAVLA 216

                  ....*..
gi 2506233547 224 EGNVIFD 230
Cdd:COG1127   217 DGKIIAE 223
ABC_NikE_OppD_transporters cd03257
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ...
1-228 2.80e-36

ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.


Pssm-ID: 213224 [Multi-domain]  Cd Length: 228  Bit Score: 128.39  E-value: 2.80e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   1 MLVLKGVTKTFnKSTVNEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHR--- 77
Cdd:cd03257     1 LLEVKNLSVSF-PTGGGSVKALDDVSFSIKKGETLGLVGESGSGKSTLARAILGLLKPTSGSIIFDGKDLLKLSRRLrki 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  78 RATDLGRVFQDPM-----RGTAADmQIVENLalaarrgesrgLSWGITRDERAsYRERLAELDLGL---EERLTSKVGLL 149
Cdd:cd03257    80 RRKEIQMVFQDPMsslnpRMTIGE-QIAEPL-----------RIHGKLSKKEA-RKEAVLLLLVGVglpEEVLNRYPHEL 146
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2506233547 150 SGGQRQALTLLMAILKKPKLLLLDEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNVI 228
Cdd:cd03257   147 SGGQRQRVAIARALALNPKLLIADEPTSALDVSVQAQILDLLKKLQEELGLTLLFITHDLGVVAKIADRVAVMYAGKIV 225
ABC_Iron-Siderophores_B12_Hemin cd03214
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ...
16-228 6.47e-36

ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.


Pssm-ID: 213181 [Multi-domain]  Cd Length: 180  Bit Score: 126.01  E-value: 6.47e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  16 VNEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRATDLGRVFQdpmrgtaa 95
Cdd:cd03214     9 YGGRTVLDDLSLSIEAGEIVGILGPNGAGKSTLLKTLAGLLKPSSGEILLDGKDLASLSPKELARKIAYVPQ-------- 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  96 dmqivenlALAArrgesrglswgitrderasyrerlaeldLGLEERLTSKVGLLSGGQRQALTLLMAILKKPKLLLLDEH 175
Cdd:cd03214    81 --------ALEL----------------------------LGLAHLADRPFNELSGGERQRVLLARALAQEPPILLLDEP 124
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2506233547 176 TAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNVI 228
Cdd:cd03214   125 TSHLDIAHQIELLELLRRLARERGKTVVMVLHDLNLAARYADRVILLKDGRIV 177
ABC_NrtD_SsuB_transporters cd03293
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ...
2-222 1.34e-35

ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213260 [Multi-domain]  Cd Length: 220  Bit Score: 126.43  E-value: 1.34e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   2 LVLKGVTKTFnKSTVNEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRratd 81
Cdd:cd03293     1 LEVRNVSKTY-GGGGGAVTALEDISLSVEEGEFVALVGPSGCGKSTLLRIIAGLERPTSGEVLVDGEPVTGPGPDR---- 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  82 lGRVFQD----PMRgtaadmQIVENLALAARRGesrglswGITRDERASYRERLAELdLGLEERLTSKVGLLSGGQRQAL 157
Cdd:cd03293    76 -GYVFQQdallPWL------TVLDNVALGLELQ-------GVPKAEARERAEELLEL-VGLSGFENAYPHQLSGGMRQRV 140
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2506233547 158 TLLMAILKKPKLLLLDEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIRLGNRLIMM 222
Cdd:cd03293   141 ALARALAVDPDVLLLDEPFSALDALTREQLQEELLDIWRETGKTVLLVTHDIDEAVFLADRVVVL 205
MalK COG3839
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism]; ...
1-227 1.34e-35

ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism];


Pssm-ID: 443050 [Multi-domain]  Cd Length: 352  Bit Score: 129.81  E-value: 1.34e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   1 MLVLKGVTKTFNKstvneKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRat 80
Cdd:COG3839     3 SLELENVSKSYGG-----VEALKDIDLDIEDGEFLVLLGPSGCGKSTLLRMIAGLEDPTSGEILIGGRDVTDLPPKDR-- 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  81 DLGRVFQDP-----MrgTAAdmqivENLALAAR-RGESRGlswgiTRDERAsyrERLAELdLGLEERLTSKVGLLSGGQR 154
Cdd:COG3839    76 NIAMVFQSYalyphM--TVY-----ENIAFPLKlRKVPKA-----EIDRRV---REAAEL-LGLEDLLDRKPKQLSGGQR 139
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 155 Q------ALT-----LLMailkkpkllllDEHTAALDPKtaSKVLALTE--RLVGEHGLTTLMVTHNMNDAIRLGNRLIM 221
Cdd:COG3839   140 QrvalgrALVrepkvFLL-----------DEPLSNLDAK--LRVEMRAEikRLHRRLGTTTIYVTHDQVEAMTLADRIAV 206

                  ....*.
gi 2506233547 222 MHEGNV 227
Cdd:COG3839   207 MNDGRI 212
DppF COG1124
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...
1-254 7.79e-35

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440741 [Multi-domain]  Cd Length: 248  Bit Score: 125.30  E-value: 7.79e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   1 MLVLKGVTKTFnKSTVNEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRAT 80
Cdd:COG1124     1 MLEVRNLSVSY-GQGGRRVPVLKDVSLEVAPGESFGLVGESGSGKSTLLRALAGLERPWSGEVTFDGRPVTRRRRKAFRR 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  81 DLGRVFQDPMrgTAAD--MQIVENLALAARrgesrglswgITRdeRASYRERLAEL--DLGLEER-LTSKVGLLSGGQRQ 155
Cdd:COG1124    80 RVQMVFQDPY--ASLHprHTVDRILAEPLR----------IHG--LPDREERIAELleQVGLPPSfLDRYPHQLSGGQRQ 145
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 156 ALTLLMAILKKPKLLLLDEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNVIFDARDDE 235
Cdd:COG1124   146 RVAIARALILEPELLLLDEPTSALDVSVQAEILNLLKDLREERGLTYLFVSHDLAVVAHLCDRVAVMQNGRIVEELTVAD 225
                         250
                  ....*....|....*....
gi 2506233547 236 KRRLRVHDLLQKFEEASGG 254
Cdd:COG1124   226 LLAGPKHPYTRELLAASLA 244
ABC_Class3 cd03229
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ...
2-225 1.03e-34

ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213196 [Multi-domain]  Cd Length: 178  Bit Score: 123.07  E-value: 1.03e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   2 LVLKGVTKTFNkstvnEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRL----PEHR 77
Cdd:cd03229     1 LELKNVSKRYG-----QKTVLNDVSLNIEAGEIVALLGPSGSGKSTLLRCIAGLEEPDSGSILIDGEDLTDLedelPPLR 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  78 RatDLGRVFQDPmrGTAADMQIVENLALAarrgesrglswgitrderasyrerlaeldlgleerltskvglLSGGQRQAL 157
Cdd:cd03229    76 R--RIGMVFQDF--ALFPHLTVLENIALG------------------------------------------LSGGQQQRV 109
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2506233547 158 TLLMAILKKPKLLLLDEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIRLGNRLIMMHEG 225
Cdd:cd03229   110 ALARALAMDPDVLLLDEPTSALDPITRREVRALLKSLQAQLGITVVLVTHDLDEAARLADRVVVLRDG 177
ABC_MetN_methionine_transporter cd03258
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ...
1-228 1.70e-34

ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213225 [Multi-domain]  Cd Length: 233  Bit Score: 123.85  E-value: 1.70e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   1 MLVLKGVTKTFnKSTVNEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPE----H 76
Cdd:cd03258     1 MIELKNVSKVF-GDTGGKVTALKDVSLSVPKGEIFGIIGRSGAGKSTLIRCINGLERPTSGSVLVDGTDLTLLSGkelrK 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  77 RRAtDLGRVFQDpmRGTAADMQIVENLALAARrgesrglSWGITRDERASYRERLAELdLGLEERLTSKVGLLSGGQRQA 156
Cdd:cd03258    80 ARR-RIGMIFQH--FNLLSSRTVFENVALPLE-------IAGVPKAEIEERVLELLEL-VGLEDKADAYPAQLSGGQKQR 148
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2506233547 157 LTLLMAILKKPKLLLLDEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNVI 228
Cdd:cd03258   149 VGIARALANNPKVLLCDEATSALDPETTQSILALLRDINRELGLTIVLITHEMEVVKRICDRVAVMEKGEVV 220
FetA COG4619
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];
15-227 1.95e-34

ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443661 [Multi-domain]  Cd Length: 209  Bit Score: 123.00  E-value: 1.95e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  15 TVNEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRL--PEHRRatDLGRVFQDP--M 90
Cdd:COG4619     9 RVGGKPILSPVSLTLEAGECVAITGPSGSGKSTLLRALADLDPPTSGEIYLDGKPLSAMppPEWRR--QVAYVPQEPalW 86
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  91 RGTAADmqiveNLALAARRgesRGLSWGITRDERAsyrerLAELDLGlEERLTSKVGLLSGGQRQALTLLMAILKKPKLL 170
Cdd:COG4619    87 GGTVRD-----NLPFPFQL---RERKFDRERALEL-----LERLGLP-PDILDKPVERLSGGERQRLALIRALLLQPDVL 152
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2506233547 171 LLDEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNV 227
Cdd:COG4619   153 LLDEPTSALDPENTRRVEELLREYLAEEGRAVLWVSHDPEQIERVADRVLTLEAGRL 209
ABC_Org_Solvent_Resistant cd03261
ATP-binding cassette transport system involved in resistance to organic solvents; ABC ...
4-235 7.68e-34

ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213228 [Multi-domain]  Cd Length: 235  Bit Score: 122.23  E-value: 7.68e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   4 LKGVTKTFNKSTVnekpaLTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRR---AT 80
Cdd:cd03261     3 LRGLTKSFGGRTV-----LKGVDLDVRRGEILAIIGPSGSGKSTLLRLIVGLLRPDSGEVLIDGEDISGLSEAELyrlRR 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  81 DLGRVFQDpmrgtAA---DMQIVENLALAARRGesrglswgiTRDERASYRERLAE-LDL-GLEERLTSKVGLLSGGQRQ 155
Cdd:cd03261    78 RMGMLFQS-----GAlfdSLTVFENVAFPLREH---------TRLSEEEIREIVLEkLEAvGLRGAEDLYPAELSGGMKK 143
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 156 ALTLLMAILKKPKLLLLDEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNVIFDARDDE 235
Cdd:cd03261   144 RVALARALALDPELLLYDEPTAGLDPIASGVIDDLIRSLKKELGLTSIMVTHDLDTAFAIADRIAVLYDGKIVAEGTPEE 223
LivF COG0410
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid ...
1-239 1.24e-33

ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid transport and metabolism];


Pssm-ID: 440179 [Multi-domain]  Cd Length: 236  Bit Score: 121.63  E-value: 1.24e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   1 MLVLKGVTKTFNKStvnekPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRAt 80
Cdd:COG0410     3 MLEVENLHAGYGGI-----HVLHGVSLEVEEGEIVALLGRNGAGKTTLLKAISGLLPPRSGSIRFDGEDITGLPPHRIA- 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  81 DLG--------RVFqdpmrgtaADMQIVENLALAARrgesrglswgiTRDERASYRERLAE-LDL--GLEERLTSKVGLL 149
Cdd:COG0410    77 RLGigyvpegrRIF--------PSLTVEENLLLGAY-----------ARRDRAEVRADLERvYELfpRLKERRRQRAGTL 137
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 150 SGGQRQALT----------LLMailkkpklllLDEHTAALDPKTASKVLALTERLVGEhGLTTLMVTHNMNDAIRLGNRL 219
Cdd:COG0410   138 SGGEQQMLAigralmsrpkLLL----------LDEPSLGLAPLIVEEIFEIIRRLNRE-GVTILLVEQNARFALEIADRA 206
                         250       260
                  ....*....|....*....|....*.
gi 2506233547 220 IMMHEGNVIFD------ARDDEKRRL 239
Cdd:COG0410   207 YVLERGRIVLEgtaaelLADPEVREA 232
ABC_phnC TIGR02315
phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of ...
1-231 1.72e-33

phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of phosphorus-containing organic compound with a stable direct C-P bond rather than a C-O-P linkage. A number of bacterial species have operons, typically about 14 genes in size, with genes for ATP-dependent transport of phosphonates, degradation, and regulation of the expression of the system. Members of this protein family are the ATP-binding cassette component of tripartite ABC transporters of phosphonates. [Transport and binding proteins, Anions]


Pssm-ID: 131368 [Multi-domain]  Cd Length: 243  Bit Score: 121.64  E-value: 1.72e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   1 MLVLKGVTKTFNkstvNEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSR-----LPE 75
Cdd:TIGR02315   1 MLEVENLSKVYP----NGKQALKNINLNINPGEFVAIIGPSGAGKSTLLRCINRLVEPSSGSILLEGTDITKlrgkkLRK 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  76 HRRATdlGRVFQDpmrgtaadMQIVENLA-----LAARRGESRGLSWGITRDERASYRERLAELD-LGLEERLTSKVGLL 149
Cdd:TIGR02315  77 LRRRI--GMIFQH--------YNLIERLTvlenvLHGRLGYKPTWRSLLGRFSEEDKERALSALErVGLADKAYQRADQL 146
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 150 SGGQRQALTLLMAILKKPKLLLLDEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNVIF 229
Cdd:TIGR02315 147 SGGQQQRVAIARALAQQPDLILADEPIASLDPKTSKQVMDYLKRINKEDGITVIINLHQVDLAKKYADRIVGLKAGEIVF 226

                  ..
gi 2506233547 230 DA 231
Cdd:TIGR02315 227 DG 228
NatA COG4555
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, ...
1-247 3.79e-33

ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 443618 [Multi-domain]  Cd Length: 243  Bit Score: 120.73  E-value: 3.79e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   1 MLVLKGVTKTFNKstvneKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRAt 80
Cdd:COG4555     1 MIEVENLSKKYGK-----VPALKDVSFTAKDGEITGLLGPNGAGKTTLLRMLAGLLKPDSGSILIDGEDVRKEPREARR- 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  81 DLGRVFQDpmRGTAADMQIVENLALAARrgesrglSWGITRDERASYRERLAELdLGLEERLTSKVGLLSGGQRQALTLL 160
Cdd:COG4555    75 QIGVLPDE--RGLYDRLTVRENIRYFAE-------LYGLFDEELKKRIEELIEL-LGLEEFLDRRVGELSTGMKKKVALA 144
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 161 MAILKKPKLLLLDEHTAALDPKTASKVLALTERLvGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNVIFDARDDEKRRLR 240
Cdd:COG4555   145 RALVHDPKVLLLDEPTNGLDVMARRLLREILRAL-KKEGKTVLFSSHIMQEVEALCDRVVILHKGKVVAQGSLDELREEI 223

                  ....*..
gi 2506233547 241 VHDLLQK 247
Cdd:COG4555   224 GEENLED 230
ECF_ATPase_1 TIGR04520
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ...
17-230 1.58e-32

energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the upstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 275313 [Multi-domain]  Cd Length: 268  Bit Score: 119.84  E-value: 1.58e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  17 NEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDG---RDVSRLPEHRRAtdLGRVFQDPmrgt 93
Cdd:TIGR04520  13 SEKPALKNVSLSIEKGEFVAIIGHNGSGKSTLAKLLNGLLLPTSGKVTVDGldtLDEENLWEIRKK--VGMVFQNP---- 86
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  94 aaDMQIV------------ENLalaarrgesrglswGITRDErasYRERLAE-LDL-GLEERLTSKVGLLSGGQRQ--AL 157
Cdd:TIGR04520  87 --DNQFVgatveddvafglENL--------------GVPREE---MRKRVDEaLKLvGMEDFRDREPHLLSGGQKQrvAI 147
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2506233547 158 TLLMA------ILkkpkllllDEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIrLGNRLIMMHEGNVIFD 230
Cdd:TIGR04520 148 AGVLAmrpdiiIL--------DEATSMLDPKGRKEVLETIRKLNKEEGITVISITHDMEEAV-LADRVIVMNKGKIVAE 217
ABC_ModC_like cd03299
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely ...
22-228 5.58e-32

ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely related to ModC. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213266 [Multi-domain]  Cd Length: 235  Bit Score: 117.44  E-value: 5.58e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  22 LTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRatDLGRVFQD----PmrgtaaDM 97
Cdd:cd03299    15 LKNVSLEVERGDYFVILGPTGSGKSVLLETIAGFIKPDSGKILLNGKDITNLPPEKR--DISYVPQNyalfP------HM 86
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  98 QIVENLALAARrgesrglswgITRDERASYRERLAEL--DLGLEERLTSKVGLLSGGQRQALTLLMAILKKPKLLLLDEH 175
Cdd:cd03299    87 TVYKNIAYGLK----------KRKVDKKEIERKVLEIaeMLGIDHLLNRKPETLSGGEQQRVAIARALVVNPKILLLDEP 156
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2506233547 176 TAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNVI 228
Cdd:cd03299   157 FSALDVRTKEKLREELKKIRKEFGVTVLHVTHDFEEAWALADKVAIMLNGKLI 209
GlnQ COG1126
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and ...
1-231 6.31e-32

ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 440743 [Multi-domain]  Cd Length: 239  Bit Score: 117.40  E-value: 6.31e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   1 MLVLKGVTKTFNKSTVnekpaLTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRA- 79
Cdd:COG1126     1 MIEIENLHKSFGDLEV-----LKGISLDVEKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTITVDGEDLTDSKKDINKl 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  80 -TDLGRVFQD----PmrgtaaDMQIVENLALAARRgeSRGLSwgitrdeRASYRER-LAELD-LGLEERLTSKVGLLSGG 152
Cdd:COG1126    76 rRKVGMVFQQfnlfP------HLTVLENVTLAPIK--VKKMS-------KAEAEERaMELLErVGLADKADAYPAQLSGG 140
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 153 QRQ------ALT-----LLMailkkpkllllDEHTAALDPKTASKVLALTERLVGEhGLTTLMVTHNMNDAIRLGNRLIM 221
Cdd:COG1126   141 QQQrvaiarALAmepkvMLF-----------DEPTSALDPELVGEVLDVMRDLAKE-GMTMVVVTHEMGFAREVADRVVF 208
                         250
                  ....*....|
gi 2506233547 222 MHEGNVIFDA 231
Cdd:COG1126   209 MDGGRIVEEG 218
AbcC COG1135
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];
1-228 8.59e-32

ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 440750 [Multi-domain]  Cd Length: 339  Bit Score: 119.41  E-value: 8.59e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   1 MLVLKGVTKTFnKSTVNEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGvfaL---DGGQVILDGRDVSRLPEH- 76
Cdd:COG1135     1 MIELENLSKTF-PTKGGPVTALDDVSLTIEKGEIFGIIGYSGAGKSTLIRCINL---LerpTSGSVLVDGVDLTALSERe 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  77 ----RRatDLGRVFQDP---MRGTAAdmqivENLALAARRgesrglsWGITRDERasyRERLAEL-DL-GLEERLTSKVG 147
Cdd:COG1135    77 lraaRR--KIGMIFQHFnllSSRTVA-----ENVALPLEI-------AGVPKAEI---RKRVAELlELvGLSDKADAYPS 139
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 148 LLSGGQRQ------AL----TLLMAilkkpkllllDEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMnDAIR-LG 216
Cdd:COG1135   140 QLSGGQKQrvgiarALannpKVLLC----------DEATSALDPETTRSILDLLKDINRELGLTIVLITHEM-DVVRrIC 208
                         250
                  ....*....|..
gi 2506233547 217 NRLIMMHEGNVI 228
Cdd:COG1135   209 DRVAVLENGRIV 220
glnQ PRK09493
glutamine ABC transporter ATP-binding protein GlnQ;
1-246 2.06e-31

glutamine ABC transporter ATP-binding protein GlnQ;


Pssm-ID: 181906 [Multi-domain]  Cd Length: 240  Bit Score: 116.35  E-value: 2.06e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   1 MLVLKGVTKTFNKSTVnekpaLTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDV--SRLPEHRR 78
Cdd:PRK09493    1 MIEFKNVSKHFGPTQV-----LHNIDLNIDQGEVVVIIGPSGSGKSTLLRCINKLEEITSGDLIVDGLKVndPKVDERLI 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  79 ATDLGRVFQD----PmrgtaaDMQIVENLALAARRgeSRGLSwgiTRDERASYRERLAELdlGLEERLTSKVGLLSGGQR 154
Cdd:PRK09493   76 RQEAGMVFQQfylfP------HLTALENVMFGPLR--VRGAS---KEEAEKQARELLAKV--GLAERAHHYPSELSGGQQ 142
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 155 QALTLLMAILKKPKLLLLDEHTAALDPKTASKVLALTERLvGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNVIFDARDD 234
Cdd:PRK09493  143 QRVAIARALAVKPKLMLFDEPTSALDPELRHEVLKVMQDL-AEEGMTMVIVTHEIGFAEKVASRLIFIDKGRIAEDGDPQ 221
                         250
                  ....*....|....*...
gi 2506233547 235 E------KRRLRvhDLLQ 246
Cdd:PRK09493  222 VliknppSQRLQ--EFLQ 237
ABC_PotA_N cd03300
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ...
2-227 2.16e-31

ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213267 [Multi-domain]  Cd Length: 232  Bit Score: 115.80  E-value: 2.16e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   2 LVLKGVTKTFNKSTvnekpALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRatD 81
Cdd:cd03300     1 IELENVSKFYGGFV-----ALDGVSLDIKEGEFFTLLGPSGCGKTTLLRLIAGFETPTSGEILLDGKDITNLPPHKR--P 73
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  82 LGRVFQD----PmrgtaaDMQIVENLALAARRgesRGLSwgitrdeRASYRERLAE-LDL-GLEERLTSKVGLLSGGQRQ 155
Cdd:cd03300    74 VNTVFQNyalfP------HLTVFENIAFGLRL---KKLP-------KAEIKERVAEaLDLvQLEGYANRKPSQLSGGQQQ 137
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2506233547 156 ALTLLMAILKKPKLLLLDEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNV 227
Cdd:cd03300   138 RVAIARALVNEPKVLLLDEPLGALDLKLRKDMQLELKRLQKELGITFVFVTHDQEEALTMSDRIAVMNKGKI 209
ABC_MalK_N cd03301
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ...
2-227 2.54e-31

The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.


Pssm-ID: 213268 [Multi-domain]  Cd Length: 213  Bit Score: 115.04  E-value: 2.54e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   2 LVLKGVTKTFNKstvneKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRatD 81
Cdd:cd03301     1 VELENVTKRFGN-----VTALDDLNLDIADGEFVVLLGPSGCGKTTTLRMIAGLEEPTSGRIYIGGRDVTDLPPKDR--D 73
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  82 LGRVFQD----PmrgtaaDMQIVENLALAARrgeSRGLSwgitRDERASYRERLAELdLGLEERLTSKVGLLSGGQRQAL 157
Cdd:cd03301    74 IAMVFQNyalyP------HMTVYDNIAFGLK---LRKVP----KDEIDERVREVAEL-LQIEHLLDRKPKQLSGGQRQRV 139
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 158 TLLMAILKKPKLLLLDEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNV 227
Cdd:cd03301   140 ALGRAIVREPKVFLMDEPLSNLDAKLRVQMRAELKRLQQRLGTTTIYVTHDQVEAMTMADRIAVMNDGQI 209
ZnuC COG1121
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ...
1-234 2.59e-31

ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440738 [Multi-domain]  Cd Length: 245  Bit Score: 115.96  E-value: 2.59e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   1 MLVLKGVTKTFNkstvnEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEH---- 76
Cdd:COG1121     6 AIELENLTVSYG-----GRPVLEDVSLTIPPGEFVAIVGPNGAGKSTLLKAILGLLPPTSGTVRLFGKPPRRARRRigyv 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  77 --RRATDLGrvFqdPMRgtaadmqiVENLALAARRGEsRGLSWGITRDERASYRERLAEldLGLEERLTSKVGLLSGGQR 154
Cdd:COG1121    81 pqRAEVDWD--F--PIT--------VRDVVLMGRYGR-RGLFRRPSRADREAVDEALER--VGLEDLADRPIGELSGGQQ 145
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 155 Q------ALT-----LLMailkkpkllllDEHTAALDPKTASKVLALTERLVgEHGLTTLMVTHNMNDAIRLGNRLIMMH 223
Cdd:COG1121   146 QrvllarALAqdpdlLLL-----------DEPFAGVDAATEEALYELLRELR-REGKTILVVTHDLGAVREYFDRVLLLN 213
                         250
                  ....*....|.
gi 2506233547 224 EGNVIFDARDD 234
Cdd:COG1121   214 RGLVAHGPPEE 224
ABC_ATPase cd00267
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ...
4-225 1.34e-29

ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213179 [Multi-domain]  Cd Length: 157  Bit Score: 108.87  E-value: 1.34e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   4 LKGVTKTFNKstvneKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRATDLG 83
Cdd:cd00267     2 IENLSFRYGG-----RTALDNVSLTLKAGEIVALVGPNGSGKSTLLRAIAGLLKPTSGEILIDGKDIAKLPLEELRRRIG 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  84 RVFQdpmrgtaadmqivenlalaarrgesrglswgitrderasyrerlaeldlgleerltskvglLSGGQRQALTLLMAI 163
Cdd:cd00267    77 YVPQ-------------------------------------------------------------LSGGQRQRVALARAL 95
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2506233547 164 LKKPKLLLLDEHTAALDPKTASKVLALTERLVgEHGLTTLMVTHNMNDAIRLGNRLIMMHEG 225
Cdd:cd00267    96 LLNPDLLLLDEPTSGLDPASRERLLELLRELA-EEGRTVIIVTHDPELAELAADRVIVLKDG 156
ECF_ATPase_2 TIGR04521
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ...
4-230 1.45e-29

energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the downstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 275314 [Multi-domain]  Cd Length: 277  Bit Score: 112.16  E-value: 1.45e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   4 LKGVTKTFNKSTVNEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVS-----RLPEHRR 78
Cdd:TIGR04521   3 LKNVSYIYQPGTPFEKKALDDVSLTIEDGEFVAIIGHTGSGKSTLIQHLNGLLKPTSGTVTIDGRDITakkkkKLKDLRK 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  79 atDLGRVFQDPmrgtaaDMQIVE------------NLalaarrgesrGLSwgitrDERAsyRERLAE-LDL-GLEERLTS 144
Cdd:TIGR04521  83 --KVGLVFQFP------EHQLFEetvykdiafgpkNL----------GLS-----EEEA--EERVKEaLELvGLDEEYLE 137
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 145 KVGL-LSGGQ--RQAL---------TLLMailkkpkllllDEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDA 212
Cdd:TIGR04521 138 RSPFeLSGGQmrRVAIagvlamepeVLIL-----------DEPTAGLDPKGRKEILDLFKRLHKEKGLTVILVTHSMEDV 206
                         250
                  ....*....|....*...
gi 2506233547 213 IRLGNRLIMMHEGNVIFD 230
Cdd:TIGR04521 207 AEYADRVIVMHKGKIVLD 224
ABC_PstB_phosphate_transporter cd03260
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ...
17-228 3.50e-29

ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).


Pssm-ID: 213227 [Multi-domain]  Cd Length: 227  Bit Score: 109.96  E-value: 3.50e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  17 NEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFAL-----DGGQVILDGRDVSRLP----EHRRAtdLGRVFQ 87
Cdd:cd03260    11 GDKHALKDISLDIPKGEITALIGPSGCGKSTLLRLLNRLNDLipgapDEGEVLLDGKDIYDLDvdvlELRRR--VGMVFQ 88
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  88 DPmrgTAADMQIVENLALAARrgeSRGLSWGITRDERAsyRERLAELDLGLEERLTSKVGLLSGGQRQALTLLMAILKKP 167
Cdd:cd03260    89 KP---NPFPGSIYDNVAYGLR---LHGIKLKEELDERV--EEALRKAALWDEVKDRLHALGLSGGQQQRLCLARALANEP 160
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2506233547 168 KLLLLDEHTAALDPKTASKVlaltERLVGE--HGLTTLMVTHNMNDAIRLGNRLIMMHEGNVI 228
Cdd:cd03260   161 EVLLLDEPTSALDPISTAKI----EELIAElkKEYTIVIVTHNMQQAARVADRTAFLLNGRLV 219
ABC_DR_subfamily_A cd03230
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ...
2-227 1.84e-28

ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213197 [Multi-domain]  Cd Length: 173  Bit Score: 106.33  E-value: 1.84e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   2 LVLKGVTKTFNKstvneKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRAtD 81
Cdd:cd03230     1 IEVRNLSKRYGK-----KTALDDISLTVEKGEIYGLLGPNGAGKTTLIKIILGLLKPDSGEIKVLGKDIKKEPEEVKR-R 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  82 LGRVFQDPMrgTAADMQIVENLalaarrgesrglswgitrderasyrerlaeldlgleerltskvgLLSGGQRQALTLLM 161
Cdd:cd03230    75 IGYLPEEPS--LYENLTVRENL--------------------------------------------KLSGGMKQRLALAQ 108
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2506233547 162 AILKKPKLLLLDEHTAALDPKTASKVLALTERLVGEhGLTTLMVTHNMNDAIRLGNRLIMMHEGNV 227
Cdd:cd03230   109 ALLHDPELLILDEPTSGLDPESRREFWELLRELKKE-GKTILLSSHILEEAERLCDRVAILNNGRI 173
ABC_CysA_sulfate_importer cd03296
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ...
2-228 2.08e-28

ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213263 [Multi-domain]  Cd Length: 239  Bit Score: 108.20  E-value: 2.08e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   2 LVLKGVTKTFNKStvnekPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRatD 81
Cdd:cd03296     3 IEVRNVSKRFGDF-----VALDDVSLDIPSGELVALLGPSGSGKTTLLRLIAGLERPDSGTILFGGEDATDVPVQER--N 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  82 LGRVFQDpmRGTAADMQIVENLA--LAARRGESRGLSWGItrDERASYRERLAELDlGLEERLTSKvglLSGGQRQALTL 159
Cdd:cd03296    76 VGFVFQH--YALFRHMTVFDNVAfgLRVKPRSERPPEAEI--RAKVHELLKLVQLD-WLADRYPAQ---LSGGQRQRVAL 147
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2506233547 160 LMAILKKPKLLLLDEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNVI 228
Cdd:cd03296   148 ARALAVEPKVLLLDEPFGALDAKVRKELRRWLRRLHDELHVTTVFVTHDQEEALEVADRVVVMNKGRIE 216
ABC_drug_resistance_like cd03264
ABC-type multidrug transport system, ATPase component; The biological function of this family ...
2-230 2.71e-28

ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213231 [Multi-domain]  Cd Length: 211  Bit Score: 107.28  E-value: 2.71e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   2 LVLKGVTKTFNKstvneKPALTGVDLHLEPGDFVtVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRATd 81
Cdd:cd03264     1 LQLENLTKRYGK-----KRALDGVSLTLGPGMYG-LLGPNGAGKTTLMRILATLTPPSSGTIRIDGQDVLKQPQKLRRR- 73
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  82 LGRVFQDPmrGTAADMQIVENLALAARRGesrglswGITRDERASYRERLAELdLGLEERLTSKVGLLSGGQRQALTLLM 161
Cdd:cd03264    74 IGYLPQEF--GVYPNFTVREFLDYIAWLK-------GIPSKEVKARVDEVLEL-VNLGDRAKKKIGSLSGGMRRRVGIAQ 143
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2506233547 162 AILKKPKLLLLDEHTAALDPKTASKVLALTERLVGEHglTTLMVTHNMNDAIRLGNRLIMMHEGNVIFD 230
Cdd:cd03264   144 ALVGDPSILIVDEPTAGLDPEERIRFRNLLSELGEDR--IVILSTHIVEDVESLCNQVAVLNKGKLVFE 210
MglA COG1129
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
1-228 4.42e-28

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440745 [Multi-domain]  Cd Length: 497  Bit Score: 111.65  E-value: 4.42e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   1 MLVLKGVTKTFnkSTVnekPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRL-PehRRA 79
Cdd:COG1129     4 LLEMRGISKSF--GGV---KALDGVSLELRPGEVHALLGENGAGKSTLMKILSGVYQPDSGEILLDGEPVRFRsP--RDA 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  80 TDLG--RVFQDPMrgTAADMQIVENLALAARRGESRGLSWgitRDERASYRERLAEldLGLEERLTSKVGLLSGGQRQ-- 155
Cdd:COG1129    77 QAAGiaIIHQELN--LVPNLSVAENIFLGREPRRGGLIDW---RAMRRRARELLAR--LGLDIDPDTPVGDLSVAQQQlv 149
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 156 ----ALT-----LLMailkkpkllllDEHTAALDPKTASKVLALTERLVgEHGLTTLMVTHNMNDAIRLGNRLIMMHEGN 226
Cdd:COG1129   150 eiarALSrdarvLIL-----------DEPTASLTEREVERLFRIIRRLK-AQGVAIIYISHRLDEVFEIADRVTVLRDGR 217

                  ..
gi 2506233547 227 VI 228
Cdd:COG1129   218 LV 219
ABC_HisP_GlnQ cd03262
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ...
4-225 4.54e-28

ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.


Pssm-ID: 213229 [Multi-domain]  Cd Length: 213  Bit Score: 106.85  E-value: 4.54e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   4 LKGVTKTFNKSTVnekpaLTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVS----RLPEHRRa 79
Cdd:cd03262     3 IKNLHKSFGDFHV-----LKGIDLTVKKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTIIIDGLKLTddkkNINELRQ- 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  80 tDLGRVFQD----PmrgtaaDMQIVENLALAARRgesrglSWGITRDE-RASYRERLAELdlGLEERLTSKVGLLSGGQR 154
Cdd:cd03262    77 -KVGMVFQQfnlfP------HLTVLENITLAPIK------VKGMSKAEaEERALELLEKV--GLADKADAYPAQLSGGQQ 141
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2506233547 155 QALTLLMAILKKPKLLLLDEHTAALDPKTASKVLALTERLVGEhGLTTLMVTHNMNDAIRLGNRLIMMHEG 225
Cdd:cd03262   142 QRVAIARALAMNPKVMLFDEPTSALDPELVGEVLDVMKDLAEE-GMTMVVVTHEMGFAREVADRVIFMDDG 211
cbiO PRK13637
energy-coupling factor transporter ATPase;
4-235 1.05e-27

energy-coupling factor transporter ATPase;


Pssm-ID: 237455 [Multi-domain]  Cd Length: 287  Bit Score: 107.44  E-value: 1.05e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   4 LKGVTKTFNKSTVNEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVS----RLPEHRRa 79
Cdd:PRK13637    5 IENLTHIYMEGTPFEKKALDNVNIEIEDGEFVGLIGHTGSGKSTLIQHLNGLLKPTSGKIIIDGVDITdkkvKLSDIRK- 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  80 tDLGRVFQDPmrgtaaDMQIVE-----NLALAARRgesRGLSwgitrDERASYRERLAELDLGLE-ERLTSKVGL-LSGG 152
Cdd:PRK13637   84 -KVGLVFQYP------EYQLFEetiekDIAFGPIN---LGLS-----EEEIENRVKRAMNIVGLDyEDYKDKSPFeLSGG 148
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 153 QRQALTLLMAILKKPKLLLLDEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNVIFDAR 232
Cdd:PRK13637  149 QKRRVAIAGVVAMEPKILILDEPTAGLDPKGRDEILNKIKELHKEYNMTIILVSHSMEDVAKLADRIIVMNKGKCELQGT 228

                  ...
gi 2506233547 233 DDE 235
Cdd:PRK13637  229 PRE 231
SunT COG2274
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ...
2-235 1.07e-27

ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];


Pssm-ID: 441875 [Multi-domain]  Cd Length: 711  Bit Score: 111.46  E-value: 1.07e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   2 LVLKGVTKTFNKstvNEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRL-PEHRRAt 80
Cdd:COG2274   474 IELENVSFRYPG---DSPPVLDNISLTIKPGERVAIVGRSGSGKSTLLKLLLGLYEPTSGRILIDGIDLRQIdPASLRR- 549
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  81 DLGRVFQDP--MRGTaadmqIVENLALAARrgesrglswGITRDE--RASyreRLAELD-------LGLEERLTSKVGLL 149
Cdd:COG2274   550 QIGVVLQDVflFSGT-----IRENITLGDP---------DATDEEiiEAA---RLAGLHdfiealpMGYDTVVGEGGSNL 612
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 150 SGGQRQALTLLMAILKKPKLLLLDEHTAALDPKTASKVLALTERLVgeHGLTTLMVTHNMnDAIRLGNRLIMMHEGNVIF 229
Cdd:COG2274   613 SGGQRQRLAIARALLRNPRILILDEATSALDAETEAIILENLRRLL--KGRTVIIIAHRL-STIRLADRIIVLDKGRIVE 689

                  ....*.
gi 2506233547 230 DARDDE 235
Cdd:COG2274   690 DGTHEE 695
CysA COG1118
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and ...
2-228 1.50e-27

ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440735 [Multi-domain]  Cd Length: 348  Bit Score: 108.31  E-value: 1.50e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   2 LVLKGVTKTFNKstvneKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDV-SRLPEHRRAT 80
Cdd:COG1118     3 IEVRNISKRFGS-----FTLLDDVSLEIASGELVALLGPSGSGKTTLLRIIAGLETPDSGRIVLNGRDLfTNLPPRERRV 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  81 dlGRVFQDP--MRgtaaDMQIVENLALAAR-RGESRglswgitRDERASYRERLAELDL-GLEERLTSKvglLSGGQRQ- 155
Cdd:COG1118    78 --GFVFQHYalFP----HMTVAENIAFGLRvRPPSK-------AEIRARVEELLELVQLeGLADRYPSQ---LSGGQRQr 141
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 156 -----ALT-----LLMailkkpkllllDEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIRLGNRLIMMHEG 225
Cdd:COG1118   142 valarALAvepevLLL-----------DEPFGALDAKVRKELRRWLRRLHDELGGTTVFVTHDQEEALELADRVVVMNQG 210

                  ...
gi 2506233547 226 NVI 228
Cdd:COG1118   211 RIE 213
ABC_subfamily_A cd03263
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ...
2-228 1.89e-27

ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.


Pssm-ID: 213230 [Multi-domain]  Cd Length: 220  Bit Score: 105.28  E-value: 1.89e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   2 LVLKGVTKTFNKSTvneKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRAtD 81
Cdd:cd03263     1 LQIRNLTKTYKKGT---KPAVDDLSLNVYKGEIFGLLGHNGAGKTTTLKMLTGELRPTSGTAYINGYSIRTDRKAARQ-S 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  82 LGRVFQDpmRGTAADMQIVENLALAARrgeSRGLSWGITRDERASYRErlaelDLGLEERLTSKVGLLSGGQRQALTLLM 161
Cdd:cd03263    77 LGYCPQF--DALFDELTVREHLRFYAR---LKGLPKSEIKEEVELLLR-----VLGLTDKANKRARTLSGGMKRKLSLAI 146
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2506233547 162 AILKKPKLLLLDEHTAALDPKTASKVLALTERLVgeHGLTTLMVTHNMNDAIRLGNRLIMMHEGNVI 228
Cdd:cd03263   147 ALIGGPSVLLLDEPTSGLDPASRRAIWDLILEVR--KGRSIILTTHSMDEAEALCDRIAIMSDGKLR 211
ABCC_Glucan_exporter_like cd03254
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ...
17-228 3.67e-27

ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213221 [Multi-domain]  Cd Length: 229  Bit Score: 104.61  E-value: 3.67e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  17 NEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRATDLGRVFQDP--MRGTa 94
Cdd:cd03254    14 EKKPVLKDINFSIKPGETVAIVGPTGAGKTTLINLLMRFYDPQKGQILIDGIDIRDISRKSLRSMIGVVLQDTflFSGT- 92
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  95 admqIVENLALAARrgesrglswgITRDERASYRERLAELDL-------GLEERLTSKVGLLSGGQRQALTLLMAILKKP 167
Cdd:cd03254    93 ----IMENIRLGRP----------NATDEEVIEAAKEAGAHDfimklpnGYDTVLGENGGNLSQGERQLLAIARAMLRDP 158
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2506233547 168 KLLLLDEHTAALDPKTASKVLALTERLVgeHGLTTLMVTHNMNdAIRLGNRLIMMHEGNVI 228
Cdd:cd03254   159 KILILDEATSNIDTETEKLIQEALEKLM--KGRTSIIIAHRLS-TIKNADKILVLDDGKII 216
ssuB PRK11247
aliphatic sulfonates transport ATP-binding subunit; Provisional
2-230 3.67e-27

aliphatic sulfonates transport ATP-binding subunit; Provisional


Pssm-ID: 183055 [Multi-domain]  Cd Length: 257  Bit Score: 105.53  E-value: 3.67e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   2 LVLKGVTKTFNKSTVnekpaLTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQvILDGRdvSRLPEHRRATD 81
Cdd:PRK11247   13 LLLNAVSKRYGERTV-----LNQLDLHIPAGQFVAVVGRSGCGKSTLLRLLAGLETPSAGE-LLAGT--APLAEAREDTR 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  82 LgrVFQD----PMRgtaadmQIVENLALaarrgesrglswGITRDERASYRERLAELdlGLEERLTSKVGLLSGGQRQAL 157
Cdd:PRK11247   85 L--MFQDarllPWK------KVIDNVGL------------GLKGQWRDAALQALAAV--GLADRANEWPAALSGGQKQRV 142
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2506233547 158 TLLMAILKKPKLLLLDEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNVIFD 230
Cdd:PRK11247  143 ALARALIHRPGLLLLDEPLGALDALTRIEMQDLIESLWQQHGFTVLLVTHDVSEAVAMADRVLLIEEGKIGLD 215
CydD COG4988
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease ...
2-235 4.29e-27

ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444012 [Multi-domain]  Cd Length: 563  Bit Score: 109.46  E-value: 4.29e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   2 LVLKGVTKTFNkstvNEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRATD 81
Cdd:COG4988   337 IELEDVSFSYP----GGRPALDGLSLTIPPGERVALVGPSGAGKSTLLNLLLGFLPPYSGSILINGVDLSDLDPASWRRQ 412
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  82 LGRVFQDP--MRGTaadmqIVENLALAARrgesrglswGITRDE------RASYRERLAELDLGLEERLTSKVGLLSGGQ 153
Cdd:COG4988   413 IAWVPQNPylFAGT-----IRENLRLGRP---------DASDEEleaaleAAGLDEFVAALPDGLDTPLGEGGRGLSGGQ 478
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 154 RQALTLLMAILKKPKLLLLDEHTAALDPKTASKVLALTERLVgeHGLTTLMVTHNMnDAIRLGNRLIMMHEGNVIFDARD 233
Cdd:COG4988   479 AQRLALARALLRDAPLLLLDEPTAHLDAETEAEILQALRRLA--KGRTVILITHRL-ALLAQADRILVLDDGRIVEQGTH 555

                  ..
gi 2506233547 234 DE 235
Cdd:COG4988   556 EE 557
ABC_OpuCA_Osmoprotection cd03295
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ...
2-228 5.34e-27

ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213262 [Multi-domain]  Cd Length: 242  Bit Score: 104.69  E-value: 5.34e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   2 LVLKGVTKTFNKStvneKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRATD 81
Cdd:cd03295     1 IEFENVTKRYGGG----KKAVNNLNLEIAKGEFLVLIGPSGSGKTTTMKMINRLIEPTSGEIFIDGEDIREQDPVELRRK 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  82 LGRVFQDPmrGTAADMQIVENLALAARRgesrgLSWgitrdERASYRERLAEL--DLGLE-----ERLTSKvglLSGGQR 154
Cdd:cd03295    77 IGYVIQQI--GLFPHMTVEENIALVPKL-----LKW-----PKEKIRERADELlaLVGLDpaefaDRYPHE---LSGGQQ 141
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2506233547 155 QALTLLMAILKKPKLLLLDEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNVI 228
Cdd:cd03295   142 QRVGVARALAADPPLLLMDEPFGALDPITRDQLQEEFKRLQQELGKTIVFVTHDIDEAFRLADRIAIMKNGEIV 215
ABC_Metallic_Cations cd03235
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ...
17-222 6.25e-27

ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.


Pssm-ID: 213202 [Multi-domain]  Cd Length: 213  Bit Score: 103.77  E-value: 6.25e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  17 NEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSR-------LPEHRratDLGRVFqdP 89
Cdd:cd03235    10 GGHPVLEDVSFEVKPGEFLAIVGPNGAGKSTLLKAILGLLKPTSGSIRVFGKPLEKerkrigyVPQRR---SIDRDF--P 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  90 MRgtaadmqiVENLALAARRGESRGLSWgITRDERASYRERLAEldLGLEERLTSKVGLLSGGQRQALTLLMAILKKPKL 169
Cdd:cd03235    85 IS--------VRDVVLMGLYGHKGLFRR-LSKADKAKVDEALER--VGLSELADRQIGELSGGQQQRVLLARALVQDPDL 153
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2506233547 170 LLLDEHTAALDPKTASKVLALTERLvGEHGLTTLMVTHNMNDAIRLGNRLIMM 222
Cdd:cd03235   154 LLLDEPFAGVDPKTQEDIYELLREL-RREGMTILVVTHDLGLVLEYFDRVLLL 205
ABC_Carb_Monos_I cd03216
First domain of the ATP-binding cassette component of monosaccharide transport system; This ...
2-228 6.42e-27

First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.


Pssm-ID: 213183 [Multi-domain]  Cd Length: 163  Bit Score: 102.12  E-value: 6.42e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   2 LVLKGVTKTFNKStvnekPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRL-PEHRRAT 80
Cdd:cd03216     1 LELRGITKRFGGV-----KALDGVSLSVRRGEVHALLGENGAGKSTLMKILSGLYKPDSGEILVDGKEVSFAsPRDARRA 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  81 DLGRVFQdpmrgtaadmqivenlalaarrgesrglswgitrderasyrerlaeldlgleerltskvglLSGGQRQALTLL 160
Cdd:cd03216    76 GIAMVYQ-------------------------------------------------------------LSVGERQMVEIA 94
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2506233547 161 MAILKKPKLLLLDEHTAALDPKTASKVLALTERLVgEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNVI 228
Cdd:cd03216    95 RALARNARLLILDEPTAALTPAEVERLFKVIRRLR-AQGVAVIFISHRLDEVFEIADRVTVLRDGRVV 161
YnjD COG4136
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function ...
1-224 2.56e-26

ABC-type uncharacterized transport system YnjBCD, ATPase component [General function prediction only];


Pssm-ID: 443311 [Multi-domain]  Cd Length: 211  Bit Score: 102.17  E-value: 2.56e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   1 MLVLKGVTktfnkSTVNEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAG----VFALDGgQVILDGRDVSRLPEH 76
Cdd:COG4136     1 MLSLENLT-----ITLGGRPLLAPLSLTVAPGEILTLMGPSGSGKSTLLAAIAGtlspAFSASG-EVLLNGRRLTALPAE 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  77 RRAtdLGRVFQDPMrgTAADMQIVENLALAARRGESRGLswgitRDERASyrERLAELDL-GLEERLtskVGLLSGGQRQ 155
Cdd:COG4136    75 QRR--IGILFQDDL--LFPHLSVGENLAFALPPTIGRAQ-----RRARVE--QALEEAGLaGFADRD---PATLSGGQRA 140
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2506233547 156 ALTLLMAILKKPKLLLLDEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAiRLGNRLIMMHE 224
Cdd:COG4136   141 RVALLRALLAEPRALLLDEPFSKLDAALRAQFREFVFEQIRQRGIPALLVTHDEEDA-PAAGRVLDLGN 208
ABC_ThiQ_thiamine_transporter cd03298
ATP-binding cassette domain of the thiamine transport system; Part of the ...
26-230 2.61e-26

ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213265 [Multi-domain]  Cd Length: 211  Bit Score: 102.19  E-value: 2.61e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  26 DLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRATDLgrVFQDpmRGTAADMQIVENLAL 105
Cdd:cd03298    18 DLTFAQGEITAIVGPSGSGKSTLLNLIAGFETPQSGRVLINGVDVTAAPPADRPVSM--LFQE--NNLFAHLTVEQNVGL 93
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 106 aarrGESRGLSwgITRDERASYRERLAELdlGLEERLTSKVGLLSGGQRQALTLLMAILKKPKLLLLDEHTAALDPKTAS 185
Cdd:cd03298    94 ----GLSPGLK--LTAEDRQAIEVALARV--GLAGLEKRLPGELSGGERQRVALARVLVRDKPVLLLDEPFAALDPALRA 165
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 2506233547 186 KVLALTERLVGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNVIFD 230
Cdd:cd03298   166 EMLDLVLDLHAETKMTVLMVTHQPEDAKRLAQRVVFLDNGRIAAQ 210
thiQ PRK10771
thiamine ABC transporter ATP-binding protein ThiQ;
26-235 8.04e-26

thiamine ABC transporter ATP-binding protein ThiQ;


Pssm-ID: 182716 [Multi-domain]  Cd Length: 232  Bit Score: 101.20  E-value: 8.04e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  26 DLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRATDLgrVFQDpmRGTAADMQIVENLAL 105
Cdd:PRK10771   19 DLTVERGERVAILGPSGAGKSTLLNLIAGFLTPASGSLTLNGQDHTTTPPSRRPVSM--LFQE--NNLFSHLTVAQNIGL 94
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 106 aarrgesrGLSWGITRDerASYRERLAEL--DLGLEERLTSKVGLLSGGQRQALTLLMAILKKPKLLLLDEHTAALDPKT 183
Cdd:PRK10771   95 --------GLNPGLKLN--AAQREKLHAIarQMGIEDLLARLPGQLSGGQRQRVALARCLVREQPILLLDEPFSALDPAL 164
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2506233547 184 ASKVLALTERLVGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNVIFDARDDE 235
Cdd:PRK10771  165 RQEMLTLVSQVCQERQLTLLMVSHSLEDAARIAPRSLVVADGRIAWDGPTDE 216
ABCC_MRP_Like cd03228
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ...
2-225 8.49e-26

ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213195 [Multi-domain]  Cd Length: 171  Bit Score: 99.38  E-value: 8.49e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   2 LVLKGVTKTFNKstvNEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRATD 81
Cdd:cd03228     1 IEFKNVSFSYPG---RPKPVLKDVSLTIKPGEKVAIVGPSGSGKSTLLKLLLRLYDPTSGEILIDGVDLRDLDLESLRKN 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  82 LGRVFQDP--MRGTaadmqIVENLalaarrgesrglswgitrderasyrerlaeldlgleerltskvglLSGGQRQALTL 159
Cdd:cd03228    78 IAYVPQDPflFSGT-----IRENI---------------------------------------------LSGGQRQRIAI 107
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2506233547 160 LMAILKKPKLLLLDEHTAALDPKTASKVLALTERLvgEHGLTTLMVTHNMNdAIRLGNRLIMMHEG 225
Cdd:cd03228   108 ARALLRDPPILILDEATSALDPETEALILEALRAL--AKGKTVIVIAHRLS-TIRDADRIIVLDDG 170
MdlB COG1132
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];
17-228 1.33e-25

ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];


Pssm-ID: 440747 [Multi-domain]  Cd Length: 579  Bit Score: 105.25  E-value: 1.33e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  17 NEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLP--EHRRAtdLGRVFQDPMR--G 92
Cdd:COG1132   351 GDRPVLKDISLTIPPGETVALVGPSGSGKSTLVNLLLRFYDPTSGRILIDGVDIRDLTleSLRRQ--IGVVPQDTFLfsG 428
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  93 TAAdmqivENLALAARrgesrglswGITRDE------RASYRERLAELDLGLEERLTSKVGLLSGGQRQALT-------- 158
Cdd:COG1132   429 TIR-----ENIRYGRP---------DATDEEveeaakAAQAHEFIEALPDGYDTVVGERGVNLSGGQRQRIAiarallkd 494
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2506233547 159 ---LLMailkkpkllllDEHTAALDPKTASKVLALTERLVgeHGLTTLMVTHNMNdAIRLGNRLIMMHEGNVI 228
Cdd:COG1132   495 ppiLIL-----------DEATSALDTETEALIQEALERLM--KGRTTIVIAHRLS-TIRNADRILVLDDGRIV 553
ntrCD TIGR01184
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits ...
22-225 2.17e-25

nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits of nitrate transport in bacteria and archaea. This protein belongs to the ATP-binding cassette (ABC) superfamily. It is thought that the two subunits encoded by ntrC and ntrD form the binding surface for interaction with ATP. This model is restricted in identifying ATP binding subunit associated with the nitrate transport. Nitrate assimilation is aided by other proteins derived from the operon which among others include products of ntrA - a regulatory protein; ntrB - a hydropbobic transmembrane permease and narB - a reductase. [Transport and binding proteins, Anions, Transport and binding proteins, Other]


Pssm-ID: 130252 [Multi-domain]  Cd Length: 230  Bit Score: 100.23  E-value: 2.17e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  22 LTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRAtdlgrVFQD----PMrgtaadM 97
Cdd:TIGR01184   1 LKGVNLTIQQGEFISLIGHSGCGKSTLLNLISGLAQPTSGGVILEGKQITEPGPDRMV-----VFQNysllPW------L 69
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  98 QIVENLALAARRgesrglswgITRDERASYRERLAE--LDL-GLEERLTSKVGLLSGGQRQALTLLMAILKKPKLLLLDE 174
Cdd:TIGR01184  70 TVRENIALAVDR---------VLPDLSKSERRAIVEehIALvGLTEAADKRPGQLSGGMKQRVAIARALSIRPKVLLLDE 140
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2506233547 175 HTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIRLGNRLIMMHEG 225
Cdd:TIGR01184 141 PFGALDALTRGNLQEELMQIWEEHRVTVLMVTHDVDEALLLSDRVVMLTNG 191
CeuD COG4604
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and ...
1-235 2.55e-25

ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443654 [Multi-domain]  Cd Length: 252  Bit Score: 100.54  E-value: 2.55e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   1 MLVLKGVTKTFNKSTVnekpaLTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRAT 80
Cdd:COG4604     1 MIEIKNVSKRYGGKVV-----LDDVSLTIPKGGITALIGPNGAGKSTLLSMISRLLPPDSGEVLVDGLDVATTPSRELAK 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  81 DLGRVFQDP---MRGTaadmqiVENLALAARRGESRGlswGITRDERASYRERLAELDLG-LEER-LTSkvglLSGGQRQ 155
Cdd:COG4604    76 RLAILRQENhinSRLT------VRELVAFGRFPYSKG---RLTAEDREIIDEAIAYLDLEdLADRyLDE----LSGGQRQ 142
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 156 ALTLLMAILKKPKLLLLDEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNVIFDARDDE 235
Cdd:COG4604   143 RAFIAMVLAQDTDYVLLDEPLNNLDMKHSVQMMKLLRRLADELGKTVVIVLHDINFASCYADHIVAMKDGRVVAQGTPEE 222
TauB COG4525
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];
1-222 3.19e-25

ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443596 [Multi-domain]  Cd Length: 262  Bit Score: 100.32  E-value: 3.19e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   1 MLVLKGVTKTFNKStVNEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRlPEHRRAT 80
Cdd:COG4525     3 MLTVRHVSVRYPGG-GQPQPALQDVSLTIESGEFVVALGASGCGKTTLLNLIAGFLAPSSGEITLDGVPVTG-PGADRGV 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  81 dlgrVFQD----PMRgtaadmQIVENLALAAR-RGESRglswgITRDERAsyRERLAELdlGLEERLTSKVGLLSGGQRQ 155
Cdd:COG4525    81 ----VFQKdallPWL------NVLDNVAFGLRlRGVPK-----AERRARA--EELLALV--GLADFARRRIWQLSGGMRQ 141
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2506233547 156 ------ALT-----LLMailkkpkllllDEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIRLGNRLIMM 222
Cdd:COG4525   142 rvgiarALAadprfLLM-----------DEPFGALDALTREQMQELLLDVWQRTGKGVFLITHSVEEALFLATRLVVM 208
ABC_NatA_like cd03267
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ...
4-230 3.28e-25

ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.


Pssm-ID: 213234 [Multi-domain]  Cd Length: 236  Bit Score: 99.71  E-value: 3.28e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   4 LKGVTKTFNKSTVNEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRD-VSRLPEHRRatDL 82
Cdd:cd03267    19 LIGSLKSLFKRKYREVEALKGISFTIEKGEIVGFIGPNGAGKTTTLKILSGLLQPTSGEVRVAGLVpWKRRKKFLR--RI 96
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  83 GRVFQDpmRGTAA-DMQIVENLALAARrgesrglswgITRDERASYRERLAELD--LGLEERLTSKVGLLSGGQRQALTL 159
Cdd:cd03267    97 GVVFGQ--KTQLWwDLPVIDSFYLLAA----------IYDLPPARFKKRLDELSelLDLEELLDTPVRQLSLGQRMRAEI 164
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2506233547 160 LMAILKKPKLLLLDEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNVIFD 230
Cdd:cd03267   165 AAALLHEPEILFLDEPTIGLDVVAQENIRNFLKEYNRERGTTVLLTSHYMKDIEALARRVLVIDKGRLLYD 235
YbbA COG4181
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase ...
1-235 3.67e-25

Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443338 [Multi-domain]  Cd Length: 233  Bit Score: 99.43  E-value: 3.67e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   1 MLVLKGVTKTFNKSTvNEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRAT 80
Cdd:COG4181     8 IIELRGLTKTVGTGA-GELTILKGISLEVEAGESVAIVGASGSGKSTLLGLLAGLDRPTSGTVRLAGQDLFALDEDARAR 86
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  81 DLGR----VFQD-PMRGTaadMQIVENLALAArrgESRGlswgiTRDERASYRERLAEldLGLEERLTSKVGLLSGG--Q 153
Cdd:COG4181    87 LRARhvgfVFQSfQLLPT---LTALENVMLPL---ELAG-----RRDARARARALLER--VGLGHRLDHYPAQLSGGeqQ 153
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 154 RQAL--------TLLMAilkkpkllllDEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIRLGnRLIMMHEG 225
Cdd:COG4181   154 RVALarafatepAILFA----------DEPTGNLDAATGEQIIDLLFELNRERGTTLVLVTHDPALAARCD-RVLRLRAG 222
                         250
                  ....*....|
gi 2506233547 226 NVIFDARDDE 235
Cdd:COG4181   223 RLVEDTAATA 232
CcmA COG4133
ABC-type transport system involved in cytochrome c biogenesis, ATPase component ...
1-207 1.68e-24

ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443308 [Multi-domain]  Cd Length: 206  Bit Score: 97.16  E-value: 1.68e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   1 MLVLKGVTKTFNkstvnEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRAt 80
Cdd:COG4133     2 MLEAENLSCRRG-----ERLLFSGLSFTLAAGEALALTGPNGSGKTTLLRILAGLLPPSAGEVLWNGEPIRDAREDYRR- 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  81 DLGRVFQDPmrGTAADMQIVENLALAARrgesrglSWGITRDeRASYRERLAEldLGLEERLTSKVGLLSGGQRQALTLL 160
Cdd:COG4133    76 RLAYLGHAD--GLKPELTVRENLRFWAA-------LYGLRAD-REAIDEALEA--VGLAGLADLPVRQLSAGQKRRVALA 143
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 2506233547 161 MAILKKPKLLLLDEHTAALDPKTASKVLALTERLVgEHGLTTLMVTH 207
Cdd:COG4133   144 RLLLSPAPLWLLDEPFTALDAAGVALLAELIAAHL-ARGGAVLLTTH 189
DppD COG0444
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...
1-228 1.72e-24

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440213 [Multi-domain]  Cd Length: 320  Bit Score: 99.74  E-value: 1.72e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   1 MLVLKGVTKTF--NKSTVnekPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGV---FALDGGQVILDGRDVSRLPE 75
Cdd:COG0444     1 LLEVRNLKVYFptRRGVV---KAVDGVSFDVRRGETLGLVGESGSGKSTLARAILGLlppPGITSGEILFDGEDLLKLSE 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  76 HR----RATDLGRVFQDPM-----RGTAADmQIVEnlALAARRGESRglswgitrderASYRERLAELdlgLEerltsKV 146
Cdd:COG0444    78 KElrkiRGREIQMIFQDPMtslnpVMTVGD-QIAE--PLRIHGGLSK-----------AEARERAIEL---LE-----RV 135
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 147 GL-------------LSGGQRQ------AL----TLLMAilkkpkllllDEHTAALDPKTASKVLALTERLVGEHGLTTL 203
Cdd:COG0444   136 GLpdperrldrypheLSGGMRQrvmiarALalepKLLIA----------DEPTTALDVTIQAQILNLLKDLQRELGLAIL 205
                         250       260
                  ....*....|....*....|....*
gi 2506233547 204 MVTHNMNDAIRLGNRLIMMHEGNVI 228
Cdd:COG0444   206 FITHDLGVVAEIADRVAVMYAGRIV 230
ABC_Pro_Gly_Betaine cd03294
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This ...
20-228 3.18e-24

ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This family comprises the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporters is the obligatory coupling of ATP hydrolysis to substrate translocation. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213261 [Multi-domain]  Cd Length: 269  Bit Score: 97.71  E-value: 3.18e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  20 PALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHR----RATDLGRVFQDpmRGTAA 95
Cdd:cd03294    38 VGVNDVSLDVREGEIFVIMGLSGSGKSTLLRCINRLIEPTSGKVLIDGQDIAAMSRKElrelRRKKISMVFQS--FALLP 115
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  96 DMQIVENLALaarrgesrGLS-WGITRDERasyRERLAE-LDL-GLEERLTSKVGLLSGGQRQALTLLMAILKKPKLLLL 172
Cdd:cd03294   116 HRTVLENVAF--------GLEvQGVPRAER---EERAAEaLELvGLEGWEHKYPDELSGGMQQRVGLARALAVDPDILLM 184
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2506233547 173 DEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNVI 228
Cdd:cd03294   185 DEAFSALDPLIRREMQDELLRLQAELQKTIVFITHDLDEALRLGDRIAIMKDGRLV 240
ABC_DrrA cd03265
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ...
2-228 4.62e-24

Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213232 [Multi-domain]  Cd Length: 220  Bit Score: 96.28  E-value: 4.62e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   2 LVLKGVTKTFNKSTvnekpALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRATd 81
Cdd:cd03265     1 IEVENLVKKYGDFE-----AVRGVSFRVRRGEIFGLLGPNGAGKTTTIKMLTTLLKPTSGRATVAGHDVVREPREVRRR- 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  82 LGRVFQDPmrgtAADMQIV--ENLALAARrgesrglSWGITRDERasyRERLAEL--DLGLEERLTSKVGLLSGGQRQAL 157
Cdd:cd03265    75 IGIVFQDL----SVDDELTgwENLYIHAR-------LYGVPGAER---RERIDELldFVGLLEAADRLVKTYSGGMRRRL 140
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2506233547 158 TLLMAILKKPKLLLLDEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNVI 228
Cdd:cd03265   141 EIARSLVHRPEVLFLDEPTIGLDPQTRAHVWEYIEKLKEEFGMTILLTTHYMEEAEQLCDRVAIIDHGRII 211
CydC TIGR02868
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ...
20-208 5.02e-24

thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.


Pssm-ID: 274331 [Multi-domain]  Cd Length: 530  Bit Score: 100.51  E-value: 5.02e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  20 PALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRATDLGRVFQDPMrgtAADMQI 99
Cdd:TIGR02868 349 PVLDGVSLDLPPGERVAILGPSGSGKSTLLATLAGLLDPLQGEVTLDGVPVSSLDQDEVRRRVSVCAQDAH---LFDTTV 425
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 100 VENLALAARRGESRGLSWGItrdERASYRERLAELDLGLEERLTSKVGLLSGGQRQALTLLMAILKKPKLLLLDEHTAAL 179
Cdd:TIGR02868 426 RENLRLARPDATDEELWAAL---ERVGLADWLRALPDGLDTVLGEGGARLSGGERQRLALARALLADAPILLLDEPTEHL 502
                         170       180
                  ....*....|....*....|....*....
gi 2506233547 180 DPKTASKVLALTerLVGEHGLTTLMVTHN 208
Cdd:TIGR02868 503 DAETADELLEDL--LAALSGRTVVLITHH 529
ABC_KpsT_Wzt cd03220
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ...
4-230 5.25e-24

ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.


Pssm-ID: 213187 [Multi-domain]  Cd Length: 224  Bit Score: 96.06  E-value: 5.25e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   4 LKGVTKTFNKSTVNEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLpehrratDLG 83
Cdd:cd03220    20 LKKLGILGRKGEVGEFWALKDVSFEVPRGERIGLIGRNGAGKSTLLRLLAGIYPPDSGTVTVRGRVSSLL-------GLG 92
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  84 RVFQDPMRGtaadmqiVENLALaarrgesRGLSWGITRDERASYRERLAELDlGLEERLTSKVGLLSGGQRQALTLLMAI 163
Cdd:cd03220    93 GGFNPELTG-------RENIYL-------NGRLLGLSRKEIDEKIDEIIEFS-ELGDFIDLPVKTYSSGMKARLAFAIAT 157
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2506233547 164 LKKPKLLLLDEHTAALDPKTASKVLALTERLVgEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNVIFD 230
Cdd:cd03220   158 ALEPDILLIDEVLAVGDAAFQEKCQRRLRELL-KQGKTVILVSHDPSSIKRLCDRALVLEKGKIRFD 223
ABC_ModC_molybdenum_transporter cd03297
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ...
31-231 7.41e-24

ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213264 [Multi-domain]  Cd Length: 214  Bit Score: 95.44  E-value: 7.41e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  31 PGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGR--DVSR----LPEHRRAtdLGRVFQDpmrgtAA---DMQIVE 101
Cdd:cd03297    22 NEEVTGIFGASGAGKSTLLRCIAGLEKPDGGTIVLNGTvlFDSRkkinLPPQQRK--IGLVFQQ-----YAlfpHLNVRE 94
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 102 NLALAARRGESRglswgitrDERASYRERLAELdlGLEERLTSKVGLLSGGQRQALTLLMAILKKPKLLLLDEHTAALDP 181
Cdd:cd03297    95 NLAFGLKRKRNR--------EDRISVDELLDLL--GLDHLLNRYPAQLSGGEKQRVALARALAAQPELLLLDEPFSALDR 164
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 2506233547 182 KTASKVLALTERLVGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNVIFDA 231
Cdd:cd03297   165 ALRLQLLPELKQIKKNLNIPVIFVTHDLSEAEYLADRIVVMEDGRLQYIG 214
PRK13633 PRK13633
energy-coupling factor transporter ATPase;
17-230 9.05e-24

energy-coupling factor transporter ATPase;


Pssm-ID: 237453 [Multi-domain]  Cd Length: 280  Bit Score: 97.08  E-value: 9.05e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  17 NEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVS---RLPEHRRATdlGRVFQDPmrgt 93
Cdd:PRK13633   21 TEKLALDDVNLEVKKGEFLVILGRNGSGKSTIAKHMNALLIPSEGKVYVDGLDTSdeeNLWDIRNKA--GMVFQNP---- 94
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  94 aaDMQIV-----ENLALAARrgesrglSWGITRDErasYRERLAEL--DLGLEERLTSKVGLLSGGQRQALTLLMAILKK 166
Cdd:PRK13633   95 --DNQIVativeEDVAFGPE-------NLGIPPEE---IRERVDESlkKVGMYEYRRHAPHLLSGGQKQRVAIAGILAMR 162
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2506233547 167 PKLLLLDEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIRlGNRLIMMHEGNVIFD 230
Cdd:PRK13633  163 PECIIFDEPTAMLDPSGRREVVNTIKELNKKYGITIILITHYMEEAVE-ADRIIVMDSGKVVME 225
LptB COG1137
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope ...
1-235 2.28e-23

ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440752 [Multi-domain]  Cd Length: 240  Bit Score: 94.71  E-value: 2.28e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   1 MLVLKGVTKTFNKSTVnekpaLTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRAT 80
Cdd:COG1137     3 TLEAENLVKSYGKRTV-----VKDVSLEVNQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGRIFLDGEDITHLPMHKRAR 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  81 D-LGRVFQDP--MRGtaadMQIVENLALAArrgESRGLSwgitRDERasyRERLAEL--DLGLEERLTSKVGLLSGGQRQ 155
Cdd:COG1137    78 LgIGYLPQEAsiFRK----LTVEDNILAVL---ELRKLS----KKER---EERLEELleEFGITHLRKSKAYSLSGGERR 143
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 156 ------ALT------LLmailkkpkllllDEHTAALDPKTASKVLALTERLVgEHGLTTLMVTHNMNDAIRLGNRLIMMH 223
Cdd:COG1137   144 rveiarALAtnpkfiLL------------DEPFAGVDPIAVADIQKIIRHLK-ERGIGVLITDHNVRETLGICDRAYIIS 210
                         250
                  ....*....|..
gi 2506233547 224 EGNVIFDARDDE 235
Cdd:COG1137   211 EGKVLAEGTPEE 222
ABC_NatA_sodium_exporter cd03266
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ...
1-230 2.93e-23

ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.


Pssm-ID: 213233 [Multi-domain]  Cd Length: 218  Bit Score: 93.97  E-value: 2.93e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   1 MLVLKGVTKTFNKSTVNEKpALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRAt 80
Cdd:cd03266     1 MITADALTKRFRDVKKTVQ-AVDGVSFTVKPGEVTGLLGPNGAGKTTTLRMLAGLLEPDAGFATVDGFDVVKEPAEARR- 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  81 DLGRVFQDpmRGTAADMQIVENLALAARRgesrglsWGITRDERASYRERLAELdLGLEERLTSKVGLLSGGQRQALTLL 160
Cdd:cd03266    79 RLGFVSDS--TGLYDRLTARENLEYFAGL-------YGLKGDELTARLEELADR-LGMEELLDRRVGGFSTGMRQKVAIA 148
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 161 MAILKKPKLLLLDEHTAALDpKTASKVLALTERLVGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNVIFD 230
Cdd:cd03266   149 RALVHDPPVLLLDEPTTGLD-VMATRALREFIRQLRALGKCILFSTHIMQEVERLCDRVVVLHRGRVVYE 217
PRK10584 PRK10584
putative ABC transporter ATP-binding protein YbbA; Provisional
22-219 3.44e-23

putative ABC transporter ATP-binding protein YbbA; Provisional


Pssm-ID: 182569 [Multi-domain]  Cd Length: 228  Bit Score: 94.08  E-value: 3.44e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  22 LTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRAT----DLGRVFQDPMrgTAADM 97
Cdd:PRK10584   26 LTGVELVVKRGETIALIGESGSGKSTLLAILAGLDDGSSGEVSLVGQPLHQMDEEARAKlrakHVGFVFQSFM--LIPTL 103
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  98 QIVENLALAAR-RGESrglswgiTRDERASYRERLAELdlGLEERLTSKVGLLSGGQRQALTLLMAILKKPKLLLLDEHT 176
Cdd:PRK10584  104 NALENVELPALlRGES-------SRQSRNGAKALLEQL--GLGKRLDHLPAQLSGGEQQRVALARAFNGRPDVLFADEPT 174
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 2506233547 177 AALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIRLGNRL 219
Cdd:PRK10584  175 GNLDRQTGDKIADLLFSLNREHGTTLILVTHDLQLAARCDRRL 217
ABC_YhbG cd03218
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ...
2-235 5.00e-23

ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.


Pssm-ID: 213185 [Multi-domain]  Cd Length: 232  Bit Score: 93.76  E-value: 5.00e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   2 LVLKGVTKTFNKSTVnekpaLTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRATD 81
Cdd:cd03218     1 LRAENLSKRYGKRKV-----VNGVSLSVKQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGKILLDGQDITKLPMHKRARL 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  82 -LGRVFQDP--MRgtaaDMQIVENLALAArrgESRGLSwgitRDERasyRERLAEL--DLGLEERLTSKVGLLSGGQRQA 156
Cdd:cd03218    76 gIGYLPQEAsiFR----KLTVEENILAVL---EIRGLS----KKER---EEKLEELleEFHITHLRKSKASSLSGGERRR 141
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2506233547 157 LTLLMAILKKPKLLLLDEHTAALDPKTASKVLALTERLVgEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNVIFDARDDE 235
Cdd:cd03218   142 VEIARALATNPKFLLLDEPFAGVDPIAVQDIQKIIKILK-DRGIGVLITDHNVRETLSITDRAYIIYEGKVLAEGTPEE 219
ModC COG4148
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and ...
25-228 5.39e-23

ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, ATPase component ModC is part of the Pathway/BioSystem: Molybdopterin biosynthesis


Pssm-ID: 443319 [Multi-domain]  Cd Length: 358  Bit Score: 95.94  E-value: 5.39e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  25 VDLHLePGDFVTVI-GGNGAGKSTLLNSIAGVFALDGGQVILDGR---DVSR---LPEHRRAtdLGRVFQDPM------- 90
Cdd:COG4148    18 VDFTL-PGRGVTALfGPSGSGKTTLLRAIAGLERPDSGRIRLGGEvlqDSARgifLPPHRRR--IGYVFQEARlfphlsv 94
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  91 RGtaadmqiveNLALAARRgesrglswgITRDERASYRERLAELdLGLEERLTSKVGLLSGGQRQALTLLMAILKKPKLL 170
Cdd:COG4148    95 RG---------NLLYGRKR---------APRAERRISFDEVVEL-LGIGHLLDRRPATLSGGERQRVAIGRALLSSPRLL 155
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2506233547 171 LLDEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNVI 228
Cdd:COG4148   156 LMDEPLAALDLARKAEILPYLERLRDELDIPILYVSHSLDEVARLADHVVLLEQGRVV 213
metN PRK11153
DL-methionine transporter ATP-binding subunit; Provisional
1-228 6.66e-23

DL-methionine transporter ATP-binding subunit; Provisional


Pssm-ID: 236863 [Multi-domain]  Cd Length: 343  Bit Score: 95.64  E-value: 6.66e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   1 MLVLKGVTKTFNKSTvNEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEH---- 76
Cdd:PRK11153    1 MIELKNISKVFPQGG-RTIHALNNVSLHIPAGEIFGVIGASGAGKSTLIRCINLLERPTSGRVLVDGQDLTALSEKelrk 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  77 -RRatDLGRVFQD---PMRGTAADmqiveNLALAARrgesrglswgITRDERASYRERLAEL-DL-GLEERLTSKVGLLS 150
Cdd:PRK11153   80 aRR--QIGMIFQHfnlLSSRTVFD-----NVALPLE----------LAGTPKAEIKARVTELlELvGLSDKADRYPAQLS 142
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2506233547 151 GGQRQALTLLMAILKKPKLLLLDEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNVI 228
Cdd:PRK11153  143 GGQKQRVAIARALASNPKVLLCDEATSALDPATTRSILELLKDINRELGLTIVLITHEMDVVKRICDRVAVIDAGRLV 220
cbiO PRK13635
energy-coupling factor ABC transporter ATP-binding protein;
17-228 7.17e-23

energy-coupling factor ABC transporter ATP-binding protein;


Pssm-ID: 184195 [Multi-domain]  Cd Length: 279  Bit Score: 94.31  E-value: 7.17e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  17 NEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSR--LPEHRRatDLGRVFQDPmrgta 94
Cdd:PRK13635   18 AATYALKDVSFSVYEGEWVAIVGHNGSGKSTLAKLLNGLLLPEAGTITVGGMVLSEetVWDVRR--QVGMVFQNP----- 90
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  95 aDMQIV-----ENLALAArrgESRGlswgITRDERAsyrERLAE-LDL-GLEERLTSKVGLLSGGQRQALTLLMAILKKP 167
Cdd:PRK13635   91 -DNQFVgatvqDDVAFGL---ENIG----VPREEMV---ERVDQaLRQvGMEDFLNREPHRLSGGQKQRVAIAGVLALQP 159
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2506233547 168 KLLLLDEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIRlGNRLIMMHEGNVI 228
Cdd:PRK13635  160 DIIILDEATSMLDPRGRREVLETVRQLKEQKGITVLSITHDLDEAAQ-ADRVIVMNKGEIL 219
cbiO PRK13645
energy-coupling factor transporter ATPase;
2-228 8.86e-23

energy-coupling factor transporter ATPase;


Pssm-ID: 184204 [Multi-domain]  Cd Length: 289  Bit Score: 94.30  E-value: 8.86e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   2 LVLKGVTKTFNKSTVNEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDG----RDVSRLPEHR 77
Cdd:PRK13645    7 IILDNVSYTYAKKTPFEFKALNNTSLTFKKNKVTCVIGTTGSGKSTMIQLTNGLIISETGQTIVGDyaipANLKKIKEVK 86
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  78 R-ATDLGRVFQDPmrgtaaDMQIVENLAlaarrgeSRGLSWG---ITRDERASYRERLAELDL-GLEERLTSKVGL-LSG 151
Cdd:PRK13645   87 RlRKEIGLVFQFP------EYQLFQETI-------EKDIAFGpvnLGENKQEAYKKVPELLKLvQLPEDYVKRSPFeLSG 153
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2506233547 152 GQRQALTLLMAILKKPKLLLLDEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNVI 228
Cdd:PRK13645  154 GQKRRVALAGIIAMDGNTLVLDEPTGGLDPKGEEDFINLFERLNKEYKKRIIMVTHNMDQVLRIADEVIVMHEGKVI 230
cbiO PRK13634
cobalt transporter ATP-binding subunit; Provisional
2-228 8.94e-23

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237454 [Multi-domain]  Cd Length: 290  Bit Score: 94.32  E-value: 8.94e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   2 LVLKGVTKTFNKSTVNEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSrlpEHRRATD 81
Cdd:PRK13634    3 ITFQKVEHRYQYKTPFERRALYDVNVSIPSGSYVAIIGHTGSGKSTLLQHLNGLLQPTSGTVTIGERVIT---AGKKNKK 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  82 L-------GRVFQDPmrgtaaDMQIVENLALaarRGESRG-LSWGITRDE-RASYRERLAELdlGLEERLTSKVGL-LSG 151
Cdd:PRK13634   80 LkplrkkvGIVFQFP------EHQLFEETVE---KDICFGpMNFGVSEEDaKQKAREMIELV--GLPEELLARSPFeLSG 148
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2506233547 152 GQ--RQALTLLMAILKKPKLLllDEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNVI 228
Cdd:PRK13634  149 GQmrRVAIAGVLAMEPEVLVL--DEPTAGLDPKGRKEMMEMFYKLHKEKGLTTVLVTHSMEDAARYADQIVVMHKGTVF 225
ABC_putative_ATPase cd03269
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ...
2-228 1.47e-22

ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213236 [Multi-domain]  Cd Length: 210  Bit Score: 91.96  E-value: 1.47e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   2 LVLKGVTKTFNkstvnEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRratd 81
Cdd:cd03269     1 LEVENVTKRFG-----RVTALDDISFSVEKGEIFGLLGPNGAGKTTTIRMILGIILPDSGEVLFDGKPLDIAARNR---- 71
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  82 LGRVFQDpmRGTAADMQIVENLA-LAARRGESRglswgitRDERASYRERLAEldLGLEERLTSKVGLLSGGQRQALTLL 160
Cdd:cd03269    72 IGYLPEE--RGLYPKMKVIDQLVyLAQLKGLKK-------EEARRRIDEWLER--LELSEYANKRVEELSKGNQQKVQFI 140
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2506233547 161 MAILKKPKLLLLDEHTAALDPKTASKVLALTERLVGEhGLTTLMVTHNMNDAIRLGNRLIMMHEGNVI 228
Cdd:cd03269   141 AAVIHDPELLILDEPFSGLDPVNVELLKDVIRELARA-GKTVILSTHQMELVEELCDRVLLLNKGRAV 207
ABC_FtsE cd03292
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ...
2-227 2.01e-22

Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages


Pssm-ID: 213259 [Multi-domain]  Cd Length: 214  Bit Score: 91.70  E-value: 2.01e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   2 LVLKGVTKTFNKSTvnekPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLpeHRRAT- 80
Cdd:cd03292     1 IEFINVTKTYPNGT----AALDGINISISAGEFVFLVGPSGAGKSTLLKLIYKEELPTSGTIRVNGQDVSDL--RGRAIp 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  81 ----DLGRVFQDPMrgTAADMQIVENLALAARrgesrglswgITRDERASYRERLAE-LDL-GLEERLTSKVGLLSGGQR 154
Cdd:cd03292    75 ylrrKIGVVFQDFR--LLPDRNVYENVAFALE----------VTGVPPREIRKRVPAaLELvGLSHKHRALPAELSGGEQ 142
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2506233547 155 QALTLLMAILKKPKLLLLDEHTAALDPKTASKVLALTERlVGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNV 227
Cdd:cd03292   143 QRVAIARAIVNSPTILIADEPTGNLDPDTTWEIMNLLKK-INKAGTTVVVATHAKELVDTTRHRVIALERGKL 214
ABCC_bacteriocin_exporters cd03245
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ...
4-230 4.38e-22

ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.


Pssm-ID: 213212 [Multi-domain]  Cd Length: 220  Bit Score: 91.11  E-value: 4.38e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   4 LKGVTKTFNKStvnEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRATDLG 83
Cdd:cd03245     5 FRNVSFSYPNQ---EIPALDNVSLTIRAGEKVAIIGRVGSGKSTLLKLLAGLYKPTSGSVLLDGTDIRQLDPADLRRNIG 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  84 RVFQDPM--RGTaadmqIVENLALAARRGESRGLswgITRDERASYRERLAELDLGLEERLTSKVGLLSGGQRQALTLLM 161
Cdd:cd03245    82 YVPQDVTlfYGT-----LRDNITLGAPLADDERI---LRAAELAGVTDFVNKHPNGLDLQIGERGRGLSGGQRQAVALAR 153
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2506233547 162 AILKKPKLLLLDEHTAALDPKTASKVLALTERLVGehGLTTLMVTHNMNdAIRLGNRLIMMHEGNVIFD 230
Cdd:cd03245   154 ALLNDPPILLLDEPTSAMDMNSEERLKERLRQLLG--DKTLIIITHRPS-LLDLVDRIIVMDSGRIVAD 219
CydC COG4987
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease ...
2-228 4.41e-22

ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444011 [Multi-domain]  Cd Length: 569  Bit Score: 94.83  E-value: 4.41e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   2 LVLKGVTKTFNKStvnEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRATD 81
Cdd:COG4987   334 LELEDVSFRYPGA---GRPVLDGLSLTLPPGERVAIVGPSGSGKSTLLALLLRFLDPQSGSITLGGVDLRDLDEDDLRRR 410
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  82 LGRVFQDP--MRGTaadmqIVENLALAARrgesrglswGITRDE------RASYRERLAELDLGLEERLTSKVGLLSGGQ 153
Cdd:COG4987   411 IAVVPQRPhlFDTT-----LRENLRLARP---------DATDEElwaaleRVGLGDWLAALPDGLDTWLGEGGRRLSGGE 476
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2506233547 154 RQALTLLMAILKKPKLLLLDEHTAALDPKTASKVLALTERLVGEHglTTLMVTHNMNdAIRLGNRLIMMHEGNVI 228
Cdd:COG4987   477 RRRLALARALLRDAPILLLDEPTEGLDAATEQALLADLLEALAGR--TVLLITHRLA-GLERMDRILVLEDGRIV 548
cbiO PRK13646
energy-coupling factor transporter ATPase;
7-229 4.54e-22

energy-coupling factor transporter ATPase;


Pssm-ID: 184205 [Multi-domain]  Cd Length: 286  Bit Score: 92.54  E-value: 4.54e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   7 VTKTFNKSTVNEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVsrlpeHRRATD----- 81
Cdd:PRK13646    8 VSYTYQKGTPYEHQAIHDVNTEFEQGKYYAIVGQTGSGKSTLIQNINALLKPTTGTVTVDDITI-----THKTKDkyirp 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  82 ----LGRVFQDPmrgtaaDMQIVENLAlaARRGESRGLSWGITRDERASYRERLAeLDLGLEERLTSKVGL-LSGGQRQA 156
Cdd:PRK13646   83 vrkrIGMVFQFP------ESQLFEDTV--EREIIFGPKNFKMNLDEVKNYAHRLL-MDLGFSRDVMSQSPFqMSGGQMRK 153
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2506233547 157 LTLLMAILKKPKLLLLDEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNVIF 229
Cdd:PRK13646  154 IAIVSILAMNPDIIVLDEPTAGLDPQSKRQVMRLLKSLQTDENKTIILVSHDMNEVARYADEVIVMKEGSIVS 226
COG4559 COG4559
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];
15-235 4.57e-22

ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443620 [Multi-domain]  Cd Length: 258  Bit Score: 91.72  E-value: 4.57e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  15 TVNEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRATdlgrvfqdpMRG-- 92
Cdd:COG4559    10 RLGGRTLLDDVSLTLRPGELTAIIGPNGAGKSTLLKLLTGELTPSSGEVRLNGRPLAAWSPWELAR---------RRAvl 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  93 ----------TAAdmQIVEnLALAARRGESRglswgitRDERASyRERLAELDL-GLEERLTSKvglLSGGQRQ------ 155
Cdd:COG4559    81 pqhsslafpfTVE--EVVA-LGRAPHGSSAA-------QDRQIV-REALALVGLaHLAGRSYQT---LSGGEQQrvqlar 146
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 156 ALT------------LLMailkkpkllllDEHTAALDPKTASKVLALTERLVgEHGLTTLMVTHNMNDAIRLGNRLIMMH 223
Cdd:COG4559   147 VLAqlwepvdggprwLFL-----------DEPTSALDLAHQHAVLRLARQLA-RRGGGVVAVLHDLNLAAQYADRILLLH 214
                         250
                  ....*....|..
gi 2506233547 224 EGNVIFDARDDE 235
Cdd:COG4559   215 QGRLVAQGTPEE 226
potA PRK09452
spermidine/putrescine ABC transporter ATP-binding protein PotA;
4-227 5.04e-22

spermidine/putrescine ABC transporter ATP-binding protein PotA;


Pssm-ID: 236523 [Multi-domain]  Cd Length: 375  Bit Score: 93.47  E-value: 5.04e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   4 LKGVTKTFNkstvnEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLP-EHRratDL 82
Cdd:PRK09452   17 LRGISKSFD-----GKEVISNLDLTINNGEFLTLLGPSGCGKTTVLRLIAGFETPDSGRIMLDGQDITHVPaENR---HV 88
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  83 GRVFQD----PmrgtaaDMQIVENLALAARrgesrglswgITRDERASYRERLAE-LDL-GLEERLTSKVGLLSGGQRQA 156
Cdd:PRK09452   89 NTVFQSyalfP------HMTVFENVAFGLR----------MQKTPAAEITPRVMEaLRMvQLEEFAQRKPHQLSGGQQQR 152
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2506233547 157 LTLLMAILKKPKLLLLDEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNV 227
Cdd:PRK09452  153 VAIARAVVNKPKVLLLDESLSALDYKLRKQMQNELKALQRKLGITFVFVTHDQEEALTMSDRIVVMRDGRI 223
MsbA_lipidA TIGR02203
lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide ...
18-228 5.59e-22

lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide chain transporter in the ATP-binding cassette (ABC) transporter family, MsbA, which exports lipid A. It may also act in multidrug resistance. Lipid A, a part of lipopolysaccharide, is found in the outer leaflet of the outer membrane of most Gram-negative bacteria. Members of this family are restricted to the Proteobacteria (although lipid A is more broadly distributed) and often are clustered with lipid A biosynthesis genes. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other]


Pssm-ID: 131258 [Multi-domain]  Cd Length: 571  Bit Score: 94.78  E-value: 5.59e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  18 EKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVS--RLPEHRRATDLgrVFQDPMrgtAA 95
Cdd:TIGR02203 344 DRPALDSISLVIEPGETVALVGRSGSGKSTLVNLIPRFYEPDSGQILLDGHDLAdyTLASLRRQVAL--VSQDVV---LF 418
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  96 DMQIVENLALAARRGESRGlswGITRDERASY-RERLAELDLGLEERLTSKVGLLSGGQRQALTLLMAILKKPKLLLLDE 174
Cdd:TIGR02203 419 NDTIANNIAYGRTEQADRA---EIERALAAAYaQDFVDKLPLGLDTPIGENGVLLSGGQRQRLAIARALLKDAPILILDE 495
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2506233547 175 HTAALDPKTASKVLALTERLVgeHGLTTLMVTHNMNdAIRLGNRLIMMHEGNVI 228
Cdd:TIGR02203 496 ATSALDNESERLVQAALERLM--QGRTTLVIAHRLS-TIEKADRIVVMDDGRIV 546
cbiO TIGR01166
cobalt transport protein ATP-binding subunit; This model describes the ATP binding subunit of ...
17-208 6.24e-22

cobalt transport protein ATP-binding subunit; This model describes the ATP binding subunit of the multisubunit cobalt transporter in bacteria and its equivalents in archaea. The model is restricted to ATP subunit that is a part of the cobalt transporter, which belongs to the ABC transporter superfamily (ATP Binding Cassette). The model excludes ATP binding subunit that are associated with other transporters belonging to ABC transporter superfamily. This superfamily includes two groups, one which catalyze the uptake of small molecules, including ions from the external milieu and the other group which is engaged in the efflux of small molecular weight compounds and ions from within the cell. Energy derived from the hydrolysis of ATP drive the both the process of uptake and efflux. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 130234 [Multi-domain]  Cd Length: 190  Bit Score: 89.79  E-value: 6.24e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  17 NEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGR--DVSR--LPEHRRAtdLGRVFQDPmrg 92
Cdd:TIGR01166   3 GGPEVLKGLNFAAERGEVLALLGANGAGKSTLLLHLNGLLRPQSGAVLIDGEplDYSRkgLLERRQR--VGLVFQDP--- 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  93 taaDMQIvenlaLAARRGESRG---LSWGITRDE-RASYRERLAELDL-GLEERLTSkvgLLSGGQRQALTLLMAILKKP 167
Cdd:TIGR01166  78 ---DDQL-----FAADVDQDVAfgpLNLGLSEAEvERRVREALTAVGAsGLRERPTH---CLSGGEKKRVAIAGAVAMRP 146
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 2506233547 168 KLLLLDEHTAALDPKTASKVLALTERLVgEHGLTTLMVTHN 208
Cdd:TIGR01166 147 DVLLLDEPTAGLDPAGREQMLAILRRLR-AEGMTVVISTHD 186
livG PRK11300
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional
21-237 1.02e-21

leucine/isoleucine/valine transporter ATP-binding subunit; Provisional


Pssm-ID: 183080 [Multi-domain]  Cd Length: 255  Bit Score: 90.82  E-value: 1.02e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  21 ALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRA-TDLGRVFQDpMRgTAADMQI 99
Cdd:PRK11300   20 AVNNVNLEVREQEIVSLIGPNGAGKTTVFNCLTGFYKPTGGTILLRGQHIEGLPGHQIArMGVVRTFQH-VR-LFREMTV 97
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 100 VENLALAARRGESRGLSWGI--TRDERASYRERLAE----LD-LGLEERLTSKVGLLSGGQRQALTLLMAILKKPKLLLL 172
Cdd:PRK11300   98 IENLLVAQHQQLKTGLFSGLlkTPAFRRAESEALDRaatwLErVGLLEHANRQAGNLAYGQQRRLEIARCMVTQPEILML 177
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2506233547 173 DEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNVIFDARDDEKR 237
Cdd:PRK11300  178 DEPAAGLNPKETKELDELIAELRNEHNVTVLLIEHDMKLVMGISDRIYVVNQGTPLANGTPEEIR 242
hmuV PRK13548
hemin importer ATP-binding subunit; Provisional
19-228 1.12e-21

hemin importer ATP-binding subunit; Provisional


Pssm-ID: 237422 [Multi-domain]  Cd Length: 258  Bit Score: 90.60  E-value: 1.12e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  19 KPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRATDLGRVFQDPmrGTAADMQ 98
Cdd:PRK13548   15 RTLLDDVSLTLRPGEVVAILGPNGAGKSTLLRALSGELSPDSGEVRLNGRPLADWSPAELARRRAVLPQHS--SLSFPFT 92
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  99 IVENLALaarrgesrGLS-WGITRDE-RASYRERLAELDL-GLEERLTSKvglLSGGQRQ------ALTLLMAILKKPKL 169
Cdd:PRK13548   93 VEEVVAM--------GRApHGLSRAEdDALVAAALAQVDLaHLAGRDYPQ---LSGGEQQrvqlarVLAQLWEPDGPPRW 161
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2506233547 170 LLLDEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNVI 228
Cdd:PRK13548  162 LLLDEPTSALDLAHQHHVLRLARQLAHERGLAVIVVLHDLNLAARYADRIVLLHQGRLV 220
YhaQ COG4152
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
1-242 1.24e-21

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 443322 [Multi-domain]  Cd Length: 298  Bit Score: 91.32  E-value: 1.24e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   1 MLVLKGVTKTFNkstvnEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSR-------- 72
Cdd:COG4152     1 MLELKGLTKRFG-----DKTAVDDVSFTVPKGEIFGLLGPNGAGKTTTIRIILGILAPDSGEVLWDGEPLDPedrrrigy 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  73 LPEHrratdlgrvfqdpmRGTAADMQIVENLALAARRgesRGLSwgitrdeRASYRERLAEL--DLGLEERLTSKVGLLS 150
Cdd:COG4152    76 LPEE--------------RGLYPKMKVGEQLVYLARL---KGLS-------KAEAKRRADEWleRLGLGDRANKKVEELS 131
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 151 GGQRQALTLLMAILKKPKLLLLDEHTAALDP------KTAskVLALTERlvgehGLTTLMVTHNMNDAIRLGNRLIMMHE 224
Cdd:COG4152   132 KGNQQKVQLIAALLHDPELLILDEPFSGLDPvnvellKDV--IRELAAK-----GTTVIFSSHQMELVEELCDRIVIINK 204
                         250       260
                  ....*....|....*....|....
gi 2506233547 225 GNVIFDARDDE------KRRLRVH 242
Cdd:COG4152   205 GRKVLSGSVDEirrqfgRNTLRLE 228
fbpC PRK11432
ferric ABC transporter ATP-binding protein;
2-228 1.47e-21

ferric ABC transporter ATP-binding protein;


Pssm-ID: 183133 [Multi-domain]  Cd Length: 351  Bit Score: 92.09  E-value: 1.47e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   2 LVLKGVTKTFNKSTVnekpaLTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRatD 81
Cdd:PRK11432    7 VVLKNITKRFGSNTV-----IDNLNLTIKQGTMVTLLGPSGCGKTTVLRLVAGLEKPTEGQIFIDGEDVTHRSIQQR--D 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  82 LGRVFQD----PmrgtaaDMQIVENLALaarrgesrGLSW-GITRDERAS-YRERLAELDL-GLEERLtskVGLLSGGQR 154
Cdd:PRK11432   80 ICMVFQSyalfP------HMSLGENVGY--------GLKMlGVPKEERKQrVKEALELVDLaGFEDRY---VDQISGGQQ 142
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2506233547 155 QALTLLMAILKKPKLLLLDEHTAALDPK----TASKVLALTERLvgehGLTTLMVTHNMNDAIRLGNRLIMMHEGNVI 228
Cdd:PRK11432  143 QRVALARALILKPKVLLFDEPLSNLDANlrrsMREKIRELQQQF----NITSLYVTHDQSEAFAVSDTVIVMNKGKIM 216
NupO COG3845
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ...
1-218 2.11e-21

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];


Pssm-ID: 443055 [Multi-domain]  Cd Length: 504  Bit Score: 92.78  E-value: 2.11e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   1 MLVLKGVTKTFNKSTvnekpALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVS-RLPEHRRA 79
Cdd:COG3845     5 ALELRGITKRFGGVV-----ANDDVSLTVRPGEIHALLGENGAGKSTLMKILYGLYQPDSGEILIDGKPVRiRSPRDAIA 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  80 TDLGRVFQDPMrgTAADMQIVENLALAARRGESRGLSWgitrderASYRERLAEL--DLGLEERLTSKVGLLSGGQRQ-- 155
Cdd:COG3845    80 LGIGMVHQHFM--LVPNLTVAENIVLGLEPTKGGRLDR-------KAARARIRELseRYGLDVDPDAKVEDLSVGEQQrv 150
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2506233547 156 ----AL-----TLLMailkkpkllllDEHTAALDPKTASKVLALTERLVGEhGLTTLMVTHNMNDAIRLGNR 218
Cdd:COG3845   151 eilkALyrgarILIL-----------DEPTAVLTPQEADELFEILRRLAAE-GKSIIFITHKLREVMAIADR 210
AztA NF040873
zinc ABC transporter ATP-binding protein AztA;
20-214 2.24e-21

zinc ABC transporter ATP-binding protein AztA;


Pssm-ID: 468810 [Multi-domain]  Cd Length: 191  Bit Score: 88.44  E-value: 2.24e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  20 PALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQV-ILDGRDVSRLPEHrraTDLGRVFQDPMRGTAAdmq 98
Cdd:NF040873    6 PVLHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLRPTSGTVrRAGGARVAYVPQR---SEVPDSLPLTVRDLVA--- 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  99 ivenLALAARRGESRGLswgiTRDERASYRERLAELDL-GLEERltsKVGLLSGGQRQALTLLMAILKKPKLLLLDEHTA 177
Cdd:NF040873   80 ----MGRWARRGLWRRL----TRDDRAAVDDALERVGLaDLAGR---QLGELSGGQRQRALLAQGLAQEADLLLLDEPTT 148
                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 2506233547 178 ALDPKTASKVLALTERLVGEhGLTTLMVTHNMNDAIR 214
Cdd:NF040873  149 GLDAESRERIIALLAEEHAR-GATVVVVTHDLELVRR 184
ABC_tran pfam00005
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ...
22-163 2.26e-21

ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.


Pssm-ID: 394964 [Multi-domain]  Cd Length: 150  Bit Score: 87.32  E-value: 2.26e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  22 LTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRATDLGRVFQDPmrGTAADMQIVE 101
Cdd:pfam00005   1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQDLTDDERKSLRKEIGYVFQDP--QLFPRLTVRE 78
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2506233547 102 NLALAARrgeSRGLSWGITRDERASYRERLAELDLgLEERLTSKVGLLSGGQRQALTLLMAI 163
Cdd:pfam00005  79 NLRLGLL---LKGLSKREKDARAEEALEKLGLGDL-ADRPVGERPGTLSGGQRQRVAIARAL 136
cbiO PRK13632
cobalt transporter ATP-binding subunit; Provisional
1-228 2.68e-21

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237452 [Multi-domain]  Cd Length: 271  Bit Score: 90.05  E-value: 2.68e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   1 MLVLKGVTKTFNKStvnEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSR--LPEHRr 78
Cdd:PRK13632    7 MIKVENVSFSYPNS---ENNALKNVSFEINEGEYVAILGHNGSGKSTISKILTGLLKPQSGEIKIDGITISKenLKEIR- 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  79 aTDLGRVFQDPmrgtaaDMQIV-----ENLA--LAARRgesrglswgITRDERASYRERLAElDLGLEERLTSKVGLLSG 151
Cdd:PRK13632   83 -KKIGIIFQNP------DNQFIgatveDDIAfgLENKK---------VPPKKMKDIIDDLAK-KVGMEDYLDKEPQNLSG 145
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2506233547 152 GQRQALTLLMAILKKPKLLLLDEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIrLGNRLIMMHEGNVI 228
Cdd:PRK13632  146 GQKQRVAIASVLALNPEIIIFDESTSMLDPKGKREIKKIMVDLRKTRKKTLISITHDMDEAI-LADKVIVFSEGKLI 221
CydD TIGR02857
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ...
2-222 5.36e-21

thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD


Pssm-ID: 274323 [Multi-domain]  Cd Length: 529  Bit Score: 91.58  E-value: 5.36e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   2 LVLKGVTKTFNkstvNEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRATD 81
Cdd:TIGR02857 322 LEFSGVSVAYP----GRRPALRPVSFTVPPGERVALVGPSGAGKSTLLNLLLGFVDPTEGSIAVNGVPLADADADSWRDQ 397
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  82 LGRVFQDP--MRGTaadmqIVENLALaARRGESRGLSwgitrdERASYRERLAELDLGLEERLTSKVG----LLSGGQRQ 155
Cdd:TIGR02857 398 IAWVPQHPflFAGT-----IAENIRL-ARPDASDAEI------REALERAGLDEFVAALPQGLDTPIGeggaGLSGGQAQ 465
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2506233547 156 ALTLLMAILKKPKLLLLDEHTAALDPKTASKVLALTERLVGehGLTTLMVTHNMNDAIRLgNRLIMM 222
Cdd:TIGR02857 466 RLALARAFLRDAPLLLLDEPTAHLDAETEAEVLEALRALAQ--GRTVLLVTHRLALAALA-DRIVVL 529
urea_trans_UrtE TIGR03410
urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC ...
21-245 6.39e-21

urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC transporter ATP-binding subunits associated with urea transport and metabolism. This protein is found in a conserved five-gene transport operon typically found adjacent to urease genes. It was shown in Cyanobacteria that disruption leads to the loss of high-affinity urea transport activity. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274567 [Multi-domain]  Cd Length: 230  Bit Score: 87.97  E-value: 6.39e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  21 ALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRA-TDLGRVFQDpmRGTAADMQI 99
Cdd:TIGR03410  15 ILRGVSLEVPKGEVTCVLGRNGVGKTTLLKTLMGLLPVKSGSIRLDGEDITKLPPHERArAGIAYVPQG--REIFPRLTV 92
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 100 VENL--ALAARRGESRGLSwgitrderasyrERLAELDLGLEERLTSKVGLLSGGQRQALTLLMAILKKPKLLLLDEHTA 177
Cdd:TIGR03410  93 EENLltGLAALPRRSRKIP------------DEIYELFPVLKEMLGRRGGDLSGGQQQQLAIARALVTRPKLLLLDEPTE 160
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2506233547 178 ALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNVIFDARDDEKRRLRVHDLL 245
Cdd:TIGR03410 161 GIQPSIIKDIGRVIRRLRAEGGMAILLVEQYLDFARELADRYYVMERGRVVASGAGDELDEDKVRRYL 228
nickel_nikE TIGR02769
nickel import ATP-binding protein NikE; This family represents the NikE subunit of a ...
1-228 6.78e-21

nickel import ATP-binding protein NikE; This family represents the NikE subunit of a multisubunit nickel import ABC transporter complex. Nickel, once imported, may be used in urease and in certain classes of hydrogenase and superoxide dismutase. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 131816 [Multi-domain]  Cd Length: 265  Bit Score: 88.71  E-value: 6.78e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   1 MLVLKGVTKTFNKSTVNEK----PALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRL-PE 75
Cdd:TIGR02769   2 LLEVRDVTHTYRTGGLFGAkqraPVLTNVSLSIEEGETVGLLGRSGCGKSTLARLLLGLEKPAQGTVSFRGQDLYQLdRK 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  76 HRRA--TDLGRVFQDPMRGTAADMQIVENLALAARRGESRGLSwgiTRDERASYRERLAELDLGLEERLTSKvglLSGGQ 153
Cdd:TIGR02769  82 QRRAfrRDVQLVFQDSPSAVNPRMTVRQIIGEPLRHLTSLDES---EQKARIAELLDMVGLRSEDADKLPRQ---LSGGQ 155
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2506233547 154 RQALTLLMAILKKPKLLLLDEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNVI 228
Cdd:TIGR02769 156 LQRINIARALAVKPKLIVLDEAVSNLDMVLQAVILELLRKLQQAFGTAYLFITHDLRLVQSFCQRVAVMDKGQIV 230
livF PRK11614
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;
1-230 6.87e-21

high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;


Pssm-ID: 183231 [Multi-domain]  Cd Length: 237  Bit Score: 88.40  E-value: 6.87e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   1 MLVLKGVTKTFNKSTvnekpALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRAT 80
Cdd:PRK11614    5 MLSFDKVSAHYGKIQ-----ALHEVSLHINQGEIVTLIGANGAGKTTLLGTLCGDPRATSGRIVFDGKDITDWQTAKIMR 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  81 DLGRVFQDPMRgTAADMQIVENLALaarrgesrglswGITRDERASYRERLA---ELDLGLEERLTSKVGLLSGGQRQAL 157
Cdd:PRK11614   80 EAVAIVPEGRR-VFSRMTVEENLAM------------GGFFAERDQFQERIKwvyELFPRLHERRIQRAGTMSGGEQQML 146
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2506233547 158 TLLMAILKKPKLLLLDEHTAALDPKTASKVLALTERLvGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNVIFD 230
Cdd:PRK11614  147 AIGRALMSQPRLLLLDEPSLGLAPIIIQQIFDTIEQL-REQGMTIFLVEQNANQALKLADRGYVLENGHVVLE 218
phnK PRK11701
phosphonate C-P lyase system protein PhnK; Provisional
1-228 9.34e-21

phosphonate C-P lyase system protein PhnK; Provisional


Pssm-ID: 183280 [Multi-domain]  Cd Length: 258  Bit Score: 88.44  E-value: 9.34e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   1 MLVLKGVTKTFNkstvnEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGR-----DVSRLPE 75
Cdd:PRK11701    6 LLSVRGLTKLYG-----PRKGCRDVSFDLYPGEVLGIVGESGSGKTTLLNALSARLAPDAGEVHYRMRdgqlrDLYALSE 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  76 HRRA----TDLGRVFQDPMRG----TAADMQIVENL-ALAARRgesrglsWGITRDERASYRERLaELDLgleERLTSKV 146
Cdd:PRK11701   81 AERRrllrTEWGFVHQHPRDGlrmqVSAGGNIGERLmAVGARH-------YGDIRATAGDWLERV-EIDA---ARIDDLP 149
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 147 GLLSGGQRQALTLLMAILKKPKLLLLDEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGN 226
Cdd:PRK11701  150 TTFSGGMQQRLQIARNLVTHPRLVFMDEPTGGLDVSVQARLLDLLRGLVRELGLAVVIVTHDLAVARLLAHRLLVMKQGR 229

                  ..
gi 2506233547 227 VI 228
Cdd:PRK11701  230 VV 231
cbiO PRK13644
energy-coupling factor transporter ATPase;
1-230 1.17e-20

energy-coupling factor transporter ATPase;


Pssm-ID: 106587 [Multi-domain]  Cd Length: 274  Bit Score: 88.51  E-value: 1.17e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   1 MLVLKGVTKTFNKSTvnekPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDV---SRLPEHR 77
Cdd:PRK13644    1 MIRLENVSYSYPDGT----PALENINLVIKKGEYIGIIGKNGSGKSTLALHLNGLLRPQKGKVLVSGIDTgdfSKLQGIR 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  78 RAtdLGRVFQDPM-----RGTAADMQI-VENLALAARrgESRglswgiTRDERAsyrerLAELDLGLEERLTSKVglLSG 151
Cdd:PRK13644   77 KL--VGIVFQNPEtqfvgRTVEEDLAFgPENLCLPPI--EIR------KRVDRA-----LAEIGLEKYRHRSPKT--LSG 139
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2506233547 152 GQRQALTLLMAILKKPKLLLLDEHTAALDPKTASKVLALTERLvGEHGLTTLMVTHNMNDaIRLGNRLIMMHEGNVIFD 230
Cdd:PRK13644  140 GQGQCVALAGILTMEPECLIFDEVTSMLDPDSGIAVLERIKKL-HEKGKTIVYITHNLEE-LHDADRIIVMDRGKIVLE 216
tauB PRK11248
taurine ABC transporter ATP-binding subunit;
19-225 2.77e-20

taurine ABC transporter ATP-binding subunit;


Pssm-ID: 183056 [Multi-domain]  Cd Length: 255  Bit Score: 87.06  E-value: 2.77e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  19 KPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRratdlGRVFQD----PMRgta 94
Cdd:PRK11248   14 KPALEDINLTLESGELLVVLGPSGCGKTTLLNLIAGFVPYQHGSITLDGKPVEGPGAER-----GVVFQNegllPWR--- 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  95 admQIVENLALAARRGesrglswGITRDER-ASYRERLAELDL-GLEERltsKVGLLSGGQRQALTLLMAILKKPKLLLL 172
Cdd:PRK11248   86 ---NVQDNVAFGLQLA-------GVEKMQRlEIAHQMLKKVGLeGAEKR---YIWQLSGGQRQRVGIARALAANPQLLLL 152
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2506233547 173 DEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIRLGNRLIMMHEG 225
Cdd:PRK11248  153 DEPFGALDAFTREQMQTLLLKLWQETGKQVLLITHDIEEAVFMATELVLLSPG 205
potG PRK11607
putrescine ABC transporter ATP-binding subunit PotG;
1-228 3.17e-20

putrescine ABC transporter ATP-binding subunit PotG;


Pssm-ID: 183226 [Multi-domain]  Cd Length: 377  Bit Score: 88.74  E-value: 3.17e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   1 MLVLKGVTKTFNKstvneKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRAT 80
Cdd:PRK11607   19 LLEIRNLTKSFDG-----QHAVDDVSLTIYKGEIFALLGASGCGKSTLLRMLAGFEQPTAGQIMLDGVDLSHVPPYQRPI 93
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  81 DLgrVFQDpmRGTAADMQIVENLAlaarrgesrglsWGITRDE--RASYRERLAELdLGL---EERLTSKVGLLSGGQRQ 155
Cdd:PRK11607   94 NM--MFQS--YALFPHMTVEQNIA------------FGLKQDKlpKAEIASRVNEM-LGLvhmQEFAKRKPHQLSGGQRQ 156
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2506233547 156 ALTLLMAILKKPKLLLLDEHTAALDPKTASK----VLALTERLvgehGLTTLMVTHNMNDAIRLGNRLIMMHEGNVI 228
Cdd:PRK11607  157 RVALARSLAKRPKLLLLDEPMGALDKKLRDRmqleVVDILERV----GVTCVMVTHDQEEAMTMAGRIAIMNRGKFV 229
PRK11264 PRK11264
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional
1-228 3.20e-20

putative amino-acid ABC transporter ATP-binding protein YecC; Provisional


Pssm-ID: 183063 [Multi-domain]  Cd Length: 250  Bit Score: 86.73  E-value: 3.20e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   1 MLVLKGVTKTFNKSTVnekpaLTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQV------ILDGRDVSRLP 74
Cdd:PRK11264    3 AIEVKNLVKKFHGQTV-----LHGIDLEVKPGEVVAIIGPSGSGKTTLLRCINLLEQPEAGTIrvgditIDTARSLSQQK 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  75 EHRRA--TDLGRVFQD----PMRgTAADmQIVENLALAarRGESRGlswgitrDERASYRERLAELdlGLEERLTSKVGL 148
Cdd:PRK11264   78 GLIRQlrQHVGFVFQNfnlfPHR-TVLE-NIIEGPVIV--KGEPKE-------EATARARELLAKV--GLAGKETSYPRR 144
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 149 LSGGQRQALTLLMAILKKPKLLLLDEHTAALDPKTASKVLAlTERLVGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNVI 228
Cdd:PRK11264  145 LSGGQQQRVAIARALAMRPEVILFDEPTSALDPELVGEVLN-TIRQLAQEKRTMVIVTHEMSFARDVADRAIFMDQGRIV 223
TagH COG1134
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ...
1-230 4.26e-20

ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440749 [Multi-domain]  Cd Length: 245  Bit Score: 86.29  E-value: 4.26e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   1 MLVLKGVTKTF-----------------NKSTVNEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQV 63
Cdd:COG1134     4 MIEVENVSKSYrlyhepsrslkelllrrRRTRREEFWALKDVSFEVERGESVGIIGRNGAGKSTLLKLIAGILEPTSGRV 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  64 ILDGRDVSRLpehrratDLGRVFQDPMRGtaadmqiVENLALaarrgesRGLSWGITRDErasYRERLAE-LDL-GLEER 141
Cdd:COG1134    84 EVNGRVSALL-------ELGAGFHPELTG-------RENIYL-------NGRLLGLSRKE---IDEKFDEiVEFaELGDF 139
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 142 LTSKVGLLSGGQRQAL-----------TLLMailkkpkllllDEHTAALDPKTASKVLALTERLVgEHGLTTLMVTHNMN 210
Cdd:COG1134   140 IDQPVKTYSSGMRARLafavatavdpdILLV-----------DEVLAVGDAAFQKKCLARIRELR-ESGRTVIFVSHSMG 207
                         250       260
                  ....*....|....*....|
gi 2506233547 211 DAIRLGNRLIMMHEGNVIFD 230
Cdd:COG1134   208 AVRRLCDRAIWLEKGRLVMD 227
btuD PRK09536
corrinoid ABC transporter ATPase; Reviewed
1-227 8.15e-20

corrinoid ABC transporter ATPase; Reviewed


Pssm-ID: 236554 [Multi-domain]  Cd Length: 402  Bit Score: 87.59  E-value: 8.15e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   1 MLVLKGVTKTFNKSTVnekpaLTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVsrlpEHRRAT 80
Cdd:PRK09536    3 MIDVSDLSVEFGDTTV-----LDGVDLSVREGSLVGLVGPNGAGKTTLLRAINGTLTPTAGTVLVAGDDV----EALSAR 73
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  81 DLGRVFQDPMRGTAADM-----QIVEnlalaARRGESRGLSWGITRDERASYRERLAELDLG--LEERLTSkvglLSGGQ 153
Cdd:PRK09536   74 AASRRVASVPQDTSLSFefdvrQVVE-----MGRTPHRSRFDTWTETDRAAVERAMERTGVAqfADRPVTS----LSGGE 144
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2506233547 154 RQALTLLMAILKKPKLLLLDEHTAALDPKTASKVLALTERLVgEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNV 227
Cdd:PRK09536  145 RQRVLLARALAQATPVLLLDEPTASLDINHQVRTLELVRRLV-DDGKTAVAAIHDLDLAARYCDELVLLADGRV 217
PRK14247 PRK14247
phosphate ABC transporter ATP-binding protein; Provisional
2-248 1.53e-19

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172735 [Multi-domain]  Cd Length: 250  Bit Score: 84.96  E-value: 1.53e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   2 LVLKGVTKTFNKSTVnekpaLTGVDLHLEPGDFVTVIGGNGAGKSTLL---NSIAGVF--ALDGGQVILDGRDVSRLP-- 74
Cdd:PRK14247    4 IEIRDLKVSFGQVEV-----LDGVNLEIPDNTITALMGPSGSGKSTLLrvfNRLIELYpeARVSGEVYLDGQDIFKMDvi 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  75 EHRRATDLgrVFQDPmrGTAADMQIVENLALaarrgesrGLSWGITRDERASYRERL------AELDLGLEERLTSKVGL 148
Cdd:PRK14247   79 ELRRRVQM--VFQIP--NPIPNLSIFENVAL--------GLKLNRLVKSKKELQERVrwalekAQLWDEVKDRLDAPAGK 146
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 149 LSGGQRQALTLLMAILKKPKLLLLDEHTAALDPKTASKVLALTERLVGEhgLTTLMVTHNMNDAIRLGNRLIMMHEGNVI 228
Cdd:PRK14247  147 LSGGQQQRLCIARALAFQPEVLLADEPTANLDPENTAKIESLFLELKKD--MTIVLVTHFPQQAARISDYVAFLYKGQIV 224
                         250       260
                  ....*....|....*....|
gi 2506233547 229 FDARDDEKRRLRVHDLLQKF 248
Cdd:PRK14247  225 EWGPTREVFTNPRHELTEKY 244
PRK09984 PRK09984
phosphonate ABC transporter ATP-binding protein;
15-230 2.31e-19

phosphonate ABC transporter ATP-binding protein;


Pssm-ID: 182182 [Multi-domain]  Cd Length: 262  Bit Score: 84.68  E-value: 2.31e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  15 TVNEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALD---GGQVILDGRDVSRlpEHRRATDL-------GR 84
Cdd:PRK09984   13 TFNQHQALHAVDLNIHHGEMVALLGPSGSGKSTLLRHLSGLITGDksaGSHIELLGRTVQR--EGRLARDIrksrantGY 90
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  85 VFQDpmRGTAADMQIVENL---ALAARRGESRGLSWGITRDERASYRerlAELDLGLEERLTSKVGLLSGGQRQALTLLM 161
Cdd:PRK09984   91 IFQQ--FNLVNRLSVLENVligALGSTPFWRTCFSWFTREQKQRALQ---ALTRVGMVHFAHQRVSTLSGGQQQRVAIAR 165
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2506233547 162 AILKKPKLLLLDEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNVIFD 230
Cdd:PRK09984  166 ALMQQAKVILADEPIASLDPESARIVMDTLRDINQNDGITVVVTLHQVDYALRYCERIVALRQGHVFYD 234
ABCC_MRP_domain2 cd03244
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C ...
17-228 2.35e-19

ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resistance lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213211 [Multi-domain]  Cd Length: 221  Bit Score: 83.70  E-value: 2.35e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  17 NEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRATDLGRVFQDP--MRGTa 94
Cdd:cd03244    15 NLPPVLKNISFSIKPGEKVGIVGRTGSGKSSLLLALFRLVELSSGSILIDGVDISKIGLHDLRSRISIIPQDPvlFSGT- 93
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  95 admqIVENLALAARRGESRglSWGITrdERASYRERLAELDLGLEERLTSKVGLLSGGQRQALTLLMAILKKPKLLLLDE 174
Cdd:cd03244    94 ----IRSNLDPFGEYSDEE--LWQAL--ERVGLKEFVESLPGGLDTVVEEGGENLSVGQRQLLCLARALLRKSKILVLDE 165
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2506233547 175 HTAALDPKTASKVlaltERLVGEH--GLTTLMVTHNMnDAIRLGNRLIMMHEGNVI 228
Cdd:cd03244   166 ATASVDPETDALI----QKTIREAfkDCTVLTIAHRL-DTIIDSDRILVLDKGRVV 216
PRK10851 PRK10851
sulfate/thiosulfate ABC transporter ATP-binding protein CysA;
6-227 2.76e-19

sulfate/thiosulfate ABC transporter ATP-binding protein CysA;


Pssm-ID: 182778 [Multi-domain]  Cd Length: 353  Bit Score: 85.91  E-value: 2.76e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   6 GVTKTFNKSTVnekpaLTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLpeHRRATDLGRV 85
Cdd:PRK10851    7 NIKKSFGRTQV-----LNDISLDIPSGQMVALLGPSGSGKTTLLRIIAGLEHQTSGHIRFHGTDVSRL--HARDRKVGFV 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  86 FQDpmRGTAADMQIVENLALaarrgesrGLSWgITRDER---ASYRERLAEL----DLG-LEERLTSKvglLSGGQRQAL 157
Cdd:PRK10851   80 FQH--YALFRHMTVFDNIAF--------GLTV-LPRRERpnaAAIKAKVTQLlemvQLAhLADRYPAQ---LSGGQKQRV 145
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 158 TLLMAILKKPKLLLLDEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNV 227
Cdd:PRK10851  146 ALARALAVEPQILLLDEPFGALDAQVRKELRRWLRQLHEELKFTSVFVTHDQEEAMEVADRVVVMSQGNI 215
YejF COG4172
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ...
17-228 3.10e-19

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443332 [Multi-domain]  Cd Length: 533  Bit Score: 86.66  E-value: 3.10e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  17 NEKPALTGVDLHLEPGDFVTVIGGNGAGKS----TLLNSIAGVFALDGGQVILDGRDVSRLPEHR----RATDLGRVFQD 88
Cdd:COG4172    21 GTVEAVKGVSFDIAAGETLALVGESGSGKSvtalSILRLLPDPAAHPSGSILFDGQDLLGLSERElrriRGNRIAMIFQE 100
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  89 PMrgTAAD------MQIVENLALaarrgeSRGLSwgitrdeRASYRERLAEL--DLGL---EERLTSKVGLLSGGQRQAL 157
Cdd:COG4172   101 PM--TSLNplhtigKQIAEVLRL------HRGLS-------GAAARARALELleRVGIpdpERRLDAYPHQLSGGQRQRV 165
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2506233547 158 TLLMAILKKPKLLLLDEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNVI 228
Cdd:COG4172   166 MIAMALANEPDLLIADEPTTALDVTVQAQILDLLKDLQRELGMALLLITHDLGVVRRFADRVAVMRQGEIV 236
ABCC_MsbA cd03251
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ...
2-228 4.50e-19

ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213218 [Multi-domain]  Cd Length: 234  Bit Score: 83.43  E-value: 4.50e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   2 LVLKGVTKTFNKstvNEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVS--RLPEHRRa 79
Cdd:cd03251     1 VEFKNVTFRYPG---DGPPVLRDISLDIPAGETVALVGPSGSGKSTLVNLIPRFYDVDSGRILIDGHDVRdyTLASLRR- 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  80 tDLGRVFQDPM--RGTaadmqIVENLALAARrgesrglswGITRDE-----RASY-RERLAELDLGLEERLTSKVGLLSG 151
Cdd:cd03251    77 -QIGLVSQDVFlfNDT-----VAENIAYGRP---------GATREEveeaaRAANaHEFIMELPEGYDTVIGERGVKLSG 141
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2506233547 152 GQRQALTLLMAILKKPKLLLLDEHTAALDPKTASKVLALTERLVgeHGLTTLMVTHNMNdAIRLGNRLIMMHEGNVI 228
Cdd:cd03251   142 GQRQRIAIARALLKDPPILILDEATSALDTESERLVQAALERLM--KNRTTFVIAHRLS-TIENADRIVVLEDGKIV 215
ModF COG1119
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ...
17-230 6.08e-19

ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];


Pssm-ID: 440736 [Multi-domain]  Cd Length: 250  Bit Score: 83.21  E-value: 6.08e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  17 NEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAG-VFALDGGQVILDGRDVSR--LPEHRR-----ATDLGRVFQD 88
Cdd:COG1119    14 GGKTILDDISWTVKPGEHWAILGPNGAGKSTLLSLITGdLPPTYGNDVRLFGERRGGedVWELRKriglvSPALQLRFPR 93
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  89 PMRgtaadmqiVENLALAARRGeSRGLSWGITRDERASYRERLAELdlGLEERLTSKVGLLSGGQRQaLTLLM-AILKKP 167
Cdd:COG1119    94 DET--------VLDVVLSGFFD-SIGLYREPTDEQRERARELLELL--GLAHLADRPFGTLSQGEQR-RVLIArALVKDP 161
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2506233547 168 KLLLLDEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNVIFD 230
Cdd:COG1119   162 ELLILDEPTAGLDLGARELLLALLDKLAAEGAPTLVLVTHHVEEIPPGITHVLLLKDGRVVAA 224
cbiO PRK13650
energy-coupling factor transporter ATPase;
10-227 7.74e-19

energy-coupling factor transporter ATPase;


Pssm-ID: 184209 [Multi-domain]  Cd Length: 279  Bit Score: 83.63  E-value: 7.74e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  10 TFNKSTVNEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVS--RLPEHRRatDLGRVFQ 87
Cdd:PRK13650   11 TFKYKEDQEKYTLNDVSFHVKQGEWLSIIGHNGSGKSTTVRLIDGLLEAESGQIIIDGDLLTeeNVWDIRH--KIGMVFQ 88
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  88 DPmrgtaaDMQIV-----ENLALAArrgESRGLSwgitrdeRASYRERLAE-LDL-GLEERLTSKVGLLSGGQRQALTLL 160
Cdd:PRK13650   89 NP------DNQFVgatveDDVAFGL---ENKGIP-------HEEMKERVNEaLELvGMQDFKEREPARLSGGQKQRVAIA 152
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2506233547 161 MAILKKPKLLLLDEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMnDAIRLGNRLIMMHEGNV 227
Cdd:PRK13650  153 GAVAMRPKIIILDEATSMLDPEGRLELIKTIKGIRDDYQMTVISITHDL-DEVALSDRVLVMKNGQV 218
ABCC_Protease_Secretion cd03246
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ...
17-227 1.51e-18

ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.


Pssm-ID: 213213 [Multi-domain]  Cd Length: 173  Bit Score: 80.34  E-value: 1.51e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  17 NEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRL-PEHRRATdLGRVFQDPM--RGT 93
Cdd:cd03246    13 AEPPVLRNVSFSIEPGESLAIIGPSGSGKSTLARLILGLLRPTSGRVRLDGADISQWdPNELGDH-VGYLPQDDElfSGS 91
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  94 aadmqIVENLalaarrgesrglswgitrderasyrerlaeldlgleerltskvglLSGGQRQALTLLMAILKKPKLLLLD 173
Cdd:cd03246    92 -----IAENI---------------------------------------------LSGGQRQRLGLARALYGNPRILVLD 121
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2506233547 174 EHTAALDPKTASKVLALTERLvGEHGLTTLMVTHNMNdAIRLGNRLIMMHEGNV 227
Cdd:cd03246   122 EPNSHLDVEGERALNQAIAAL-KAAGATRIVIAHRPE-TLASADRILVLEDGRV 173
ABC_BcrA_bacitracin_resist cd03268
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily ...
2-231 1.60e-18

ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.


Pssm-ID: 213235 [Multi-domain]  Cd Length: 208  Bit Score: 81.11  E-value: 1.60e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   2 LVLKGVTKTFNKstvneKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRatD 81
Cdd:cd03268     1 LKTNDLTKTYGK-----KRVLDDISLHVKKGEIYGFLGPNGAGKTTTMKIILGLIKPDSGEITFDGKSYQKNIEALR--R 73
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  82 LGRVFQDPmrGTAADMQIVENLALAARrgesrglswgITRDERASYRERLAEldLGLEERLTSKVGLLSGGQRQALTLLM 161
Cdd:cd03268    74 IGALIEAP--GFYPNLTARENLRLLAR----------LLGIRKKRIDEVLDV--VGLKDSAKKKVKGFSLGMKQRLGIAL 139
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 162 AILKKPKLLLLDEHTAALDPKTASKVLALTERLVGEhGLTTLMVTHNMNDAIRLGNRLIMMHEGNVIFDA 231
Cdd:cd03268   140 ALLGNPDLLILDEPTNGLDPDGIKELRELILSLRDQ-GITVLISSHLLSEIQKVADRIGIINKGKLIEEG 208
PRK10247 PRK10247
putative ABC transporter ATP-binding protein YbbL; Provisional
16-226 2.11e-18

putative ABC transporter ATP-binding protein YbbL; Provisional


Pssm-ID: 182331 [Multi-domain]  Cd Length: 225  Bit Score: 81.30  E-value: 2.11e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  16 VNEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRATDLGRVFQDPMR--GT 93
Cdd:PRK10247   17 AGDAKILNNISFSLRAGEFKLITGPSGCGKSTLLKIVASLISPTSGTLLFEGEDISTLKPEIYRQQVSYCAQTPTLfgDT 96
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  94 AADmqiveNLALAarrgesrglsWGITRD--ERASYRERLAELDLGlEERLTSKVGLLSGGQRQALTLLMAILKKPKLLL 171
Cdd:PRK10247   97 VYD-----NLIFP----------WQIRNQqpDPAIFLDDLERFALP-DTILTKNIAELSGGEKQRISLIRNLQFMPKVLL 160
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2506233547 172 LDEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMN------DAIRLGNRLIMMHEGN 226
Cdd:PRK10247  161 LDEITSALDESNKHNVNEIIHRYVREQNIAVLWVTHDKDeinhadKVITLQPHAGEMQEAR 221
PstB COG1117
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; ...
17-228 4.58e-18

ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440734 [Multi-domain]  Cd Length: 258  Bit Score: 80.85  E-value: 4.58e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  17 NEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNS-------IAGVFAldGGQVILDGRDVSR----LPEHRRatDLGRV 85
Cdd:COG1117    22 GDKQALKDINLDIPENKVTALIGPSGCGKSTLLRClnrmndlIPGARV--EGEILLDGEDIYDpdvdVVELRR--RVGMV 97
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  86 FQDPmrgTAADMQIVENLALAARRGesrglswGITRderasyRERLAEL------DLGL-EE---RLTSKVGLLSGGQRQ 155
Cdd:COG1117    98 FQKP---NPFPKSIYDNVAYGLRLH-------GIKS------KSELDEIveeslrKAALwDEvkdRLKKSALGLSGGQQQ 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 156 ALT-----------LLMailkkpkllllDEHTAALDPKTASKVLALTERLVGEHglTTLMVTHNMNDAIRLGNRLIMMHE 224
Cdd:COG1117   162 RLCiaralavepevLLM-----------DEPTSALDPISTAKIEELILELKKDY--TIVIVTHNMQQAARVSDYTAFFYL 228

                  ....
gi 2506233547 225 GNVI 228
Cdd:COG1117   229 GELV 232
ABCC_Hemolysin cd03252
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ...
21-235 4.79e-18

ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.


Pssm-ID: 213219 [Multi-domain]  Cd Length: 237  Bit Score: 80.61  E-value: 4.79e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  21 ALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRL-PEHRRAtDLGRVFQDpmrGTAADMQI 99
Cdd:cd03252    17 ILDNISLRIKPGEVVGIVGRSGSGKSTLTKLIQRFYVPENGRVLVDGHDLALAdPAWLRR-QVGVVLQE---NVLFNRSI 92
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 100 VENLALaARRGESRglswgitrdERASYRERLA-------ELDLGLEERLTSKVGLLSGGQRQALTLLMAILKKPKLLLL 172
Cdd:cd03252    93 RDNIAL-ADPGMSM---------ERVIEAAKLAgahdfisELPEGYDTIVGEQGAGLSGGQRQRIAIARALIHNPRILIF 162
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2506233547 173 DEHTAALDPKTASKVLALTERLVGehGLTTLMVTHNMNdAIRLGNRLIMMHEGNVIFDARDDE 235
Cdd:cd03252   163 DEATSALDYESEHAIMRNMHDICA--GRTVIIIAHRLS-TVKNADRIIVMEKGRIVEQGSHDE 222
YejF COG4172
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ...
13-228 9.90e-18

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443332 [Multi-domain]  Cd Length: 533  Bit Score: 82.04  E-value: 9.90e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  13 KSTVNEKPALTGVDLHLEPGDFVTVIGGNGAGKSTL----LNSIAGvfaldGGQVILDGRDVSRLPEH-----RRatDLG 83
Cdd:COG4172   293 RRTVGHVKAVDGVSLTLRRGETLGLVGESGSGKSTLglalLRLIPS-----EGEIRFDGQDLDGLSRRalrplRR--RMQ 365
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  84 RVFQDPM-----RGTAAdmQIV-ENLALAARrgesrglswGITRDERasyRERLAELdlgLEErltskVGL--------- 148
Cdd:COG4172   366 VVFQDPFgslspRMTVG--QIIaEGLRVHGP---------GLSAAER---RARVAEA---LEE-----VGLdpaarhryp 423
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 149 --LSGGQRQ------ALTL----LMAilkkpkllllDEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMnDAIR-L 215
Cdd:COG4172   424 heFSGGQRQriaiarALILepklLVL----------DEPTSALDVSVQAQILDLLRDLQREHGLAYLFISHDL-AVVRaL 492
                         250
                  ....*....|...
gi 2506233547 216 GNRLIMMHEGNVI 228
Cdd:COG4172   493 AHRVMVMKDGKVV 505
AppF COG4608
ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; ...
2-210 1.23e-17

ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443658 [Multi-domain]  Cd Length: 329  Bit Score: 80.93  E-value: 1.23e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   2 LVLKGVTKTF---------NKSTVNekpALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSR 72
Cdd:COG4608     8 LEVRDLKKHFpvrgglfgrTVGVVK---AVDGVSFDIRRGETLGLVGESGCGKSTLGRLLLRLEEPTSGEILFDGQDITG 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  73 LPEHRRAtDLGR----VFQDPM-----RGTAADMqIVENLALAarrgesrglswGI-TRDERasyRERLAELdlgLEerl 142
Cdd:COG4608    85 LSGRELR-PLRRrmqmVFQDPYaslnpRMTVGDI-IAEPLRIH-----------GLaSKAER---RERVAEL---LE--- 142
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 143 tsKVGL-----------LSGGQRQ------ALTL----LMAilkkpkllllDEHTAALDPKTASKVLALTERLVGEHGLT 201
Cdd:COG4608   143 --LVGLrpehadrypheFSGGQRQrigiarALALnpklIVC----------DEPVSALDVSIQAQVLNLLEDLQDELGLT 210

                  ....*....
gi 2506233547 202 TLMVTHNMN 210
Cdd:COG4608   211 YLFISHDLS 219
PhnL COG4778
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion ...
1-222 2.06e-17

Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion transport and metabolism];


Pssm-ID: 443809 [Multi-domain]  Cd Length: 229  Bit Score: 78.63  E-value: 2.06e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   1 MLVLKGVTKTFNKSTVNEK--PALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGR----DVSRLP 74
Cdd:COG4778     4 LLEVENLSKTFTLHLQGGKrlPVLDGVSFSVAAGECVALTGPSGAGKSTLLKCIYGNYLPDSGSILVRHDggwvDLAQAS 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  75 EHR----RATDLGRVFQ----DPmRGTAADmqIVENLALAarRGESRglswgitrdERAsyRERLAEL--DLGLEERL-- 142
Cdd:COG4778    84 PREilalRRRTIGYVSQflrvIP-RVSALD--VVAEPLLE--RGVDR---------EEA--RARARELlaRLNLPERLwd 147
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 143 ----TskvglLSGGQRQALTLLMAILKKPKLLLLDEHTAALDPKTASKVLALTERLVGEhGLTTLMVTHNMNDAIRLGNR 218
Cdd:COG4778   148 lppaT-----FSGGEQQRVNIARGFIADPPLLLLDEPTASLDAANRAVVVELIEEAKAR-GTAIIGIFHDEEVREAVADR 221

                  ....
gi 2506233547 219 LIMM 222
Cdd:COG4778   222 VVDV 225
cbiO PRK13636
cobalt transporter ATP-binding subunit; Provisional
21-230 2.48e-17

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184196 [Multi-domain]  Cd Length: 283  Bit Score: 79.51  E-value: 2.48e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  21 ALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGR--DVSR--LPEHRRAtdLGRVFQDPmrgtaaD 96
Cdd:PRK13636   21 ALKGININIKKGEVTAILGGNGAGKSTLFQNLNGILKPSSGRILFDGKpiDYSRkgLMKLRES--VGMVFQDP------D 92
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  97 MQIvenLALAARRGESRG-LSWGITRDErASYRERLAELDLGLEERLTSKVGLLSGGQRQALTLLMAILKKPKLLLLDEH 175
Cdd:PRK13636   93 NQL---FSASVYQDVSFGaVNLKLPEDE-VRKRVDNALKRTGIEHLKDKPTHCLSFGQKKRVAIAGVLVMEPKVLVLDEP 168
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2506233547 176 TAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNVIFD 230
Cdd:PRK13636  169 TAGLDPMGVSEIMKLLVEMQKELGLTIIIATHDIDIVPLYCDNVFVMKEGRVILQ 223
PRK10253 PRK10253
iron-enterobactin ABC transporter ATP-binding protein;
7-228 3.61e-17

iron-enterobactin ABC transporter ATP-binding protein;


Pssm-ID: 182336 [Multi-domain]  Cd Length: 265  Bit Score: 78.87  E-value: 3.61e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   7 VTKTFNKSTVNEKpaltgVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRATDLGRVF 86
Cdd:PRK10253   13 LTLGYGKYTVAEN-----LTVEIPDGHFTAIIGPNGCGKSTLLRTLSRLMTPAHGHVWLDGEHIQHYASKEVARRIGLLA 87
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  87 QDPMrgTAADMQIVENLALAARRGESRGLSWGiTRDERASYRERLAEldlGLEERLTSKVGLLSGGQRQALTLLMAILKK 166
Cdd:PRK10253   88 QNAT--TPGDITVQELVARGRYPHQPLFTRWR-KEDEEAVTKAMQAT---GITHLADQSVDTLSGGQRQRAWIAMVLAQE 161
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2506233547 167 PKLLLLDEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNVI 228
Cdd:PRK10253  162 TAIMLLDEPTTWLDISHQIDLLELLSELNREKGYTLAAVLHDLNQACRYASHLIALREGKIV 223
PRK10619 PRK10619
histidine ABC transporter ATP-binding protein HisP;
18-227 4.18e-17

histidine ABC transporter ATP-binding protein HisP;


Pssm-ID: 182592 [Multi-domain]  Cd Length: 257  Bit Score: 78.47  E-value: 4.18e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  18 EKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSI-------AGVFALDGGQVIL----DGR----DVSRLPEHRraTDL 82
Cdd:PRK10619   17 EHEVLKGVSLQANAGDVISIIGSSGSGKSTFLRCInflekpsEGSIVVNGQTINLvrdkDGQlkvaDKNQLRLLR--TRL 94
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  83 GRVFQDpmRGTAADMQIVENLALAARrgESRGLSWGITRDERASYRERLaeldlGLEERLTSKVGL-LSGGQRQALTLLM 161
Cdd:PRK10619   95 TMVFQH--FNLWSHMTVLENVMEAPI--QVLGLSKQEARERAVKYLAKV-----GIDERAQGKYPVhLSGGQQQRVSIAR 165
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2506233547 162 AILKKPKLLLLDEHTAALDPKTASKVLALTERLvGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNV 227
Cdd:PRK10619  166 ALAMEPEVLLFDEPTSALDPELVGEVLRIMQQL-AEEGKTMVVVTHEMGFARHVSSHVIFLHQGKI 230
COG4586 COG4586
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
4-230 6.04e-17

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 443643 [Multi-domain]  Cd Length: 323  Bit Score: 78.98  E-value: 6.04e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   4 LKGVTKTFNKSTVNEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRD-VSRLPEHRRatDL 82
Cdd:COG4586    20 LKGALKGLFRREYREVEAVDDISFTIEPGEIVGFIGPNGAGKSTTIKMLTGILVPTSGEVRVLGYVpFKRRKEFAR--RI 97
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  83 GRVF-QdpmRGT-AADMQIVENLALAARrgesrglswgITRDERASYRERLAELD--LGLEERLTSKVGLLSGGQRQALT 158
Cdd:COG4586    98 GVVFgQ---RSQlWWDLPAIDSFRLLKA----------IYRIPDAEYKKRLDELVelLDLGELLDTPVRQLSLGQRMRCE 164
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2506233547 159 LLMAILKKPKLLLLDEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNVIFD 230
Cdd:COG4586   165 LAAALLHRPKILFLDEPTIGLDVVSKEAIREFLKEYNRERGTTILLTSHDMDDIEALCDRVIVIDHGRIIYD 236
ArpD COG4618
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular ...
18-240 6.10e-17

ABC-type protease/lipase transport system, ATPase and permease components [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 443660 [Multi-domain]  Cd Length: 563  Bit Score: 79.79  E-value: 6.10e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  18 EKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEhrraTDLGRVF----QDP--MR 91
Cdd:COG4618   344 KRPILRGVSFSLEPGEVLGVIGPSGSGKSTLARLLVGVWPPTAGSVRLDGADLSQWDR----EELGRHIgylpQDVelFD 419
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  92 GTaadmqIVENLA-----------LAARrgesrglswgitrdeRASYRERLAELDLGLEERLTSKVGLLSGGQRQALTLL 160
Cdd:COG4618   420 GT-----IAENIArfgdadpekvvAAAK---------------LAGVHEMILRLPDGYDTRIGEGGARLSGGQRQRIGLA 479
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 161 MAILKKPKLLLLDEHTAALDPkTASKVLALTERLVGEHGLTTLMVTHNMNdAIRLGNRLIMMHEGNVI-FDARDDEKRRL 239
Cdd:COG4618   480 RALYGDPRLVVLDEPNSNLDD-EGEAALAAAIRALKARGATVVVITHRPS-LLAAVDKLLVLRDGRVQaFGPRDEVLARL 557

                  .
gi 2506233547 240 R 240
Cdd:COG4618   558 A 558
PRK10908 PRK10908
cell division ATP-binding protein FtsE;
12-227 7.00e-17

cell division ATP-binding protein FtsE;


Pssm-ID: 182829 [Multi-domain]  Cd Length: 222  Bit Score: 77.22  E-value: 7.00e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  12 NKSTVNEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRL-----PEHRRatDLGRVF 86
Cdd:PRK10908    8 SKAYLGGRQALQGVTFHMRPGEMAFLTGHSGAGKSTLLKLICGIERPSAGKIWFSGHDITRLknrevPFLRR--QIGMIF 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  87 QDpmRGTAADMQIVENLAL----AARRGEsrglswgitrDERasyRERLAELD-LGLEERLTSKVGLLSGGQRQALTLLM 161
Cdd:PRK10908   86 QD--HHLLMDRTVYDNVAIpliiAGASGD----------DIR---RRVSAALDkVGLLDKAKNFPIQLSGGEQQRVGIAR 150
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2506233547 162 AILKKPKLLLLDEHTAALDPKTASKVLALTERLvGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNV 227
Cdd:PRK10908  151 AVVNKPAVLLADEPTGNLDDALSEGILRLFEEF-NRVGVTVLMATHDIGLISRRSYRMLTLSDGHL 215
PRK09700 PRK09700
D-allose ABC transporter ATP-binding protein AlsA;
4-248 7.12e-17

D-allose ABC transporter ATP-binding protein AlsA;


Pssm-ID: 182036 [Multi-domain]  Cd Length: 510  Bit Score: 79.83  E-value: 7.12e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   4 LKGVTKTFNKSTvnekpALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLpEHRRATDLG 83
Cdd:PRK09700    8 MAGIGKSFGPVH-----ALKSVNLTVYPGEIHALLGENGAGKSTLMKVLSGIHEPTKGTITINNINYNKL-DHKLAAQLG 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  84 --RVFQDpmRGTAADMQIVENLALAarRGESRGLsWGITRDERASYRERLAE--LDLGLEERLTSKVGLLSGGQRQALTL 159
Cdd:PRK09700   82 igIIYQE--LSVIDELTVLENLYIG--RHLTKKV-CGVNIIDWREMRVRAAMmlLRVGLKVDLDEKVANLSISHKQMLEI 156
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 160 LMAILKKPKLLLLDEHTAALDPKTASKVLALTERLVGEhGLTTLMVTHNMNDAIRLGNRLIMMHEGN-----VIFDARDD 234
Cdd:PRK09700  157 AKTLMLDAKVIIMDEPTSSLTNKEVDYLFLIMNQLRKE-GTAIVYISHKLAEIRRICDRYTVMKDGSsvcsgMVSDVSND 235
                         250
                  ....*....|....*
gi 2506233547 235 EKRRLRV-HDLLQKF 248
Cdd:PRK09700  236 DIVRLMVgRELQNRF 250
cbiO PRK13639
cobalt transporter ATP-binding subunit; Provisional
1-228 8.60e-17

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184199 [Multi-domain]  Cd Length: 275  Bit Score: 77.81  E-value: 8.60e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   1 MLVLKGVTKTFNKSTVnekpALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGR----DVSRLPEH 76
Cdd:PRK13639    1 ILETRDLKYSYPDGTE----ALKGINFKAEKGEMVALLGPNGAGKSTLFLHFNGILKPTSGEVLIKGEpikyDKKSLLEV 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  77 RRAtdLGRVFQDPmrgtaaDMQIV-----ENLALAArrgesrgLSWGITRDE-RASYRERLAELDL-GLEERLTSKvglL 149
Cdd:PRK13639   77 RKT--VGIVFQNP------DDQLFaptveEDVAFGP-------LNLGLSKEEvEKRVKEALKAVGMeGFENKPPHH---L 138
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2506233547 150 SGGQRQALTLLMAILKKPKLLLLDEHTAALDPKTASKVLALTERLvGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNVI 228
Cdd:PRK13639  139 SGGQKKRVAIAGILAMKPEIIVLDEPTSGLDPMGASQIMKLLYDL-NKEGITIIISTHDVDLVPVYADKVYVMSDGKII 216
PRK14239 PRK14239
phosphate transporter ATP-binding protein; Provisional
17-228 1.41e-16

phosphate transporter ATP-binding protein; Provisional


Pssm-ID: 184585 [Multi-domain]  Cd Length: 252  Bit Score: 76.74  E-value: 1.41e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  17 NEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALD-----GGQVILDGRDVsrlpeHRRATD-------LGR 84
Cdd:PRK14239   16 NKKKALNSVSLDFYPNEITALIGPSGSGKSTLLRSINRMNDLNpevtiTGSIVYNGHNI-----YSPRTDtvdlrkeIGM 90
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  85 VFQDPmrgTAADMQIVENLALAARrgeSRGLSWGITRDERASYRERLAELDLGLEERLTSKVGLLSGGQRQALTLLMAIL 164
Cdd:PRK14239   91 VFQQP---NPFPMSIYENVVYGLR---LKGIKDKQVLDEAVEKSLKGASIWDEVKDRLHDSALGLSGGQQQRVCIARVLA 164
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2506233547 165 KKPKLLLLDEHTAALDPKTASKVlalTERLVG-EHGLTTLMVTHNMNDAIRLGNRLIMMHEGNVI 228
Cdd:PRK14239  165 TSPKIILLDEPTSALDPISAGKI---EETLLGlKDDYTMLLVTRSMQQASRISDRTGFFLDGDLI 226
bacteriocin_ABC TIGR01193
ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The ...
20-235 1.47e-16

ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The amino terminal domain (pfam03412) processes the N-terminal leader peptide from the bacteriocin while C-terminal domains resemble ABC transporter membrane protein and ATP-binding cassette domain. In general, bacteriocins are agents which are responsible for killing or inhibiting the closely related species or even different strains of the same species. Bacteriocins are usually encoded by bacterial plasmids. Bacteriocins are named after the species and hence in literature one encounters various names e.g., leucocin from Leuconostic geldium; pedicocin from Pedicoccus acidilactici; sakacin from Lactobacillus sake etc. [Protein fate, Protein and peptide secretion and trafficking, Protein fate, Protein modification and repair, Transport and binding proteins, Other]


Pssm-ID: 130261 [Multi-domain]  Cd Length: 708  Bit Score: 79.01  E-value: 1.47e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  20 PALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRATDLGRVFQDPMRGTAAdmqI 99
Cdd:TIGR01193 488 NILSDISLTIKMNSKTTIVGMSGSGKSTLAKLLVGFFQARSGEILLNGFSLKDIDRHTLRQFINYLPQEPYIFSGS---I 564
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 100 VENLALAARRGESRGLSWGITrdERASYRERLAELDLGLEERLTSKVGLLSGGQRQALTLLMAILKKPKLLLLDEHTAAL 179
Cdd:TIGR01193 565 LENLLLGAKENVSQDEIWAAC--EIAEIKDDIENMPLGYQTELSEEGSSISGGQKQRIALARALLTDSKVLILDESTSNL 642
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2506233547 180 DPKTASKVLaltERLVGEHGLTTLMVTHNMNDAIRLgNRLIMMHEGNVIFDARDDE 235
Cdd:TIGR01193 643 DTITEKKIV---NNLLNLQDKTIIFVAHRLSVAKQS-DKIIVLDHGKIIEQGSHDE 694
HisP COG4598
ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism];
1-227 1.78e-16

ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443652 [Multi-domain]  Cd Length: 259  Bit Score: 76.76  E-value: 1.78e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   1 MLVLKGVTKTFNKSTVnekpaLTGVDLHLEPGDFVTVIGGNGAGKSTLLNSI-------AGVFALDGGQVIL-DGRDVSR 72
Cdd:COG4598     8 ALEVRDLHKSFGDLEV-----LKGVSLTARKGDVISIIGSSGSGKSTFLRCInlletpdSGEIRVGGEEIRLkPDRDGEL 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  73 LPEHRRA-----TDLGRVFQDpmRGTAADMQIVENLALAARRgesrglSWGITRDERASYRERLAElDLGLEERLTSKVG 147
Cdd:COG4598    83 VPADRRQlqrirTRLGMVFQS--FNLWSHMTVLENVIEAPVH------VLGRPKAEAIERAEALLA-KVGLADKRDAYPA 153
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 148 LLSGGQRQALTLLMAILKKPKLLLLDEHTAALDPKTASKVLALTERLVGEhGLTTLMVTHNMNDAIRLGNRLIMMHEGNV 227
Cdd:COG4598   154 HLSGGQQQRAAIARALAMEPEVMLFDEPTSALDPELVGEVLKVMRDLAEE-GRTMLVVTHEMGFARDVSSHVVFLHQGRI 232
PRK13657 PRK13657
glucan ABC transporter ATP-binding protein/ permease;
17-235 1.91e-16

glucan ABC transporter ATP-binding protein/ permease;


Pssm-ID: 184214 [Multi-domain]  Cd Length: 588  Bit Score: 78.46  E-value: 1.91e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  17 NEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEH--RRAtdLGRVFQDPMrgtA 94
Cdd:PRK13657  346 NSRQGVEDVSFEAKPGQTVAIVGPTGAGKSTLINLLQRVFDPQSGRILIDGTDIRTVTRAslRRN--IAVVFQDAG---L 420
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  95 ADMQIVENLALA---ARRGESRGLSwgitrdERASYRERLAELDLGLEERLTSKVGLLSGGQRQALTLLMAILKKPKLLL 171
Cdd:PRK13657  421 FNRSIEDNIRVGrpdATDEEMRAAA------ERAQAHDFIERKPDGYDTVVGERGRQLSGGERQRLAIARALLKDPPILI 494
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2506233547 172 LDEHTAALDPKTASKVLALTERLVgeHGLTTLMVTHNMNdAIRLGNRLIMMHEGNVIFDARDDE 235
Cdd:PRK13657  495 LDEATSALDVETEAKVKAALDELM--KGRTTFIIAHRLS-TVRNADRILVFDNGRVVESGSFDE 555
PRK13651 PRK13651
cobalt transporter ATP-binding subunit; Provisional
4-231 2.24e-16

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184210 [Multi-domain]  Cd Length: 305  Bit Score: 77.05  E-value: 2.24e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   4 LKGVTKTFNKSTVNEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRD-------------- 69
Cdd:PRK13651    5 VKNIVKIFNKKLPTELKALDNVSVEINQGEFIAIIGQTGSGKTTFIEHLNALLLPDTGTIEWIFKDeknkkktkekekvl 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  70 ---VSRLPEHRR---ATDL----GRVFQdpmrgtAADMQIVE-----NLALAARrgesrglSWGITRDE---RASYRERL 131
Cdd:PRK13651   85 eklVIQKTRFKKikkIKEIrrrvGVVFQ------FAEYQLFEqtiekDIIFGPV-------SMGVSKEEakkRAAKYIEL 151
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 132 AELDlglEERLTSKVGLLSGGQ--RQALTLLMAILKKPKLLllDEHTAALDPKTASKVLALTERLvGEHGLTTLMVTHNM 209
Cdd:PRK13651  152 VGLD---ESYLQRSPFELSGGQkrRVALAGILAMEPDFLVF--DEPTAGLDPQGVKEILEIFDNL-NKQGKTIILVTHDL 225
                         250       260
                  ....*....|....*....|..
gi 2506233547 210 NDAIRLGNRLIMMHEGNVIFDA 231
Cdd:PRK13651  226 DNVLEWTKRTIFFKDGKIIKDG 247
PRK10535 PRK10535
macrolide ABC transporter ATP-binding protein/permease MacB;
1-239 2.90e-16

macrolide ABC transporter ATP-binding protein/permease MacB;


Pssm-ID: 182528 [Multi-domain]  Cd Length: 648  Bit Score: 78.23  E-value: 2.90e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   1 MLVLKGVTKTFnKSTVNEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSI-------AGVFALDGGQVI-LDGRDVSR 72
Cdd:PRK10535    4 LLELKDIRRSY-PSGEEQVEVLKGISLDIYAGEMVAIVGASGSGKSTLMNILgcldkptSGTYRVAGQDVAtLDADALAQ 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  73 LpehrRATDLGRVFQdpmRG------TAAdmQIVENLALAArrgesrglswGITRDERasyRERLAEL--DLGLEERLTS 144
Cdd:PRK10535   83 L----RREHFGFIFQ---RYhllshlTAA--QNVEVPAVYA----------GLERKQR---LLRAQELlqRLGLEDRVEY 140
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 145 KVGLLSGGQRQALTLLMAILKKPKLLLLDEHTAALDPKTASKVLALTERLvGEHGLTTLMVTHNMNDAIRlGNRLIMMHE 224
Cdd:PRK10535  141 QPSQLSGGQQQRVSIARALMNGGQVILADEPTGALDSHSGEEVMAILHQL-RDRGHTVIIVTHDPQVAAQ-AERVIEIRD 218
                         250
                  ....*....|....*
gi 2506233547 225 GNVIFDARDDEKRRL 239
Cdd:PRK10535  219 GEIVRNPPAQEKVNV 233
lolD PRK11629
lipoprotein-releasing ABC transporter ATP-binding protein LolD;
22-221 3.72e-16

lipoprotein-releasing ABC transporter ATP-binding protein LolD;


Pssm-ID: 183244 [Multi-domain]  Cd Length: 233  Bit Score: 75.24  E-value: 3.72e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  22 LTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRAT----DLGRVFQdpMRGTAADM 97
Cdd:PRK11629   25 LHNVSFSIGEGEMMAIVGSSGSGKSTLLHLLGGLDTPTSGDVIFNGQPMSKLSSAAKAElrnqKLGFIYQ--FHHLLPDF 102
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  98 QIVENLALAARRGESRglswgitrdeRASYRERLAEL--DLGLEERLTSKVGLLSGGQRQALTLLMAILKKPKLLLLDEH 175
Cdd:PRK11629  103 TALENVAMPLLIGKKK----------PAEINSRALEMlaAVGLEHRANHRPSELSGGERQRVAIARALVNNPRLVLADEP 172
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 2506233547 176 TAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIRLGNRLIM 221
Cdd:PRK11629  173 TGNLDARNADSIFQLLGELNRLQGTAFLVVTHDLQLAKRMSRQLEM 218
PRK13537 PRK13537
nodulation factor ABC transporter ATP-binding protein NodI;
2-228 4.49e-16

nodulation factor ABC transporter ATP-binding protein NodI;


Pssm-ID: 237420 [Multi-domain]  Cd Length: 306  Bit Score: 76.38  E-value: 4.49e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   2 LVLKGVTKTFNKSTVnekpaLTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRATd 81
Cdd:PRK13537    8 IDFRNVEKRYGDKLV-----VDGLSFHVQRGECFGLLGPNGAGKTTTLRMLLGLTHPDAGSISLCGEPVPSRARHARQR- 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  82 LGRVFQ----DPmrgtaaDMQIVENLALAARRgesRGLSwgitrdeRASYRERLAEL--DLGLEERLTSKVGLLSGGQRQ 155
Cdd:PRK13537   82 VGVVPQfdnlDP------DFTVRENLLVFGRY---FGLS-------AAAARALVPPLleFAKLENKADAKVGELSGGMKR 145
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2506233547 156 ALTLLMAILKKPKLLLLDEHTAALDPKtASKVLALTERLVGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNVI 228
Cdd:PRK13537  146 RLTLARALVNDPDVLVLDEPTTGLDPQ-ARHLMWERLRSLLARGKTILLTTHFMEEAERLCDRLCVIEEGRKI 217
ABC_cobalt_CbiO_domain2 cd03226
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of ...
22-228 6.04e-16

Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.


Pssm-ID: 213193 [Multi-domain]  Cd Length: 205  Bit Score: 74.22  E-value: 6.04e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  22 LTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRlpeHRRATDLGRVFQDPmrgtaaDMQIVE 101
Cdd:cd03226    16 LDDLSLDLYAGEIIALTGKNGAGKTTLAKILAGLIKESSGSILLNGKPIKA---KERRKSIGYVMQDV------DYQLFT 86
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 102 NLAlaarrGESRGLSWGITRDERASYRERLAELDL-GLEERLTSKvglLSGGQRQALTLLMAILKKPKLLLLDEHTAALD 180
Cdd:cd03226    87 DSV-----REELLLGLKELDAGNEQAETVLKDLDLyALKERHPLS---LSGGQKQRLAIAAALLSGKDLLIFDEPTSGLD 158
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 2506233547 181 PKTASKVLALTERLVGEhGLTTLMVTHNMNDAIRLGNRLIMMHEGNVI 228
Cdd:cd03226   159 YKNMERVGELIRELAAQ-GKAVIVITHDYEFLAKVCDRVLLLANGAIV 205
ugpC PRK11650
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;
1-227 8.80e-16

sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;


Pssm-ID: 236947 [Multi-domain]  Cd Length: 356  Bit Score: 75.65  E-value: 8.80e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   1 MLVLKGVTKTFNkstvNEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRL-PEHRra 79
Cdd:PRK11650    3 GLKLQAVRKSYD----GKTQVIKGIDLDVADGEFIVLVGPSGCGKSTLLRMVAGLERITSGEIWIGGRVVNELePADR-- 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  80 tDLGRVFQD----PmrgtaaDMQIVENLALAARrgeSRGLSwgitRDERasyRERLAELD--LGLEERLTSKVGLLSGGQ 153
Cdd:PRK11650   77 -DIAMVFQNyalyP------HMSVRENMAYGLK---IRGMP----KAEI---EERVAEAAriLELEPLLDRKPRELSGGQ 139
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2506233547 154 RQALTLLMAILKKPKLLLLDEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNV 227
Cdd:PRK11650  140 RQRVAMGRAIVREPAVFLFDEPLSNLDAKLRVQMRLEIQRLHRRLKTTSLYVTHDQVEAMTLADRVVVMNGGVA 213
PRK10575 PRK10575
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;
27-228 1.06e-15

Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;


Pssm-ID: 182561 [Multi-domain]  Cd Length: 265  Bit Score: 74.44  E-value: 1.06e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  27 LHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRATDLGRVfqdPMRGTAADMQIVENLaLA 106
Cdd:PRK10575   32 LTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARKVAYL---PQQLPAAEGMTVREL-VA 107
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 107 ARRGESRGLSWGITRDERASYRERLAELDLG-LEERLtskVGLLSGGQRQALTLLMAILKKPKLLLLDEHTAALDPKTAS 185
Cdd:PRK10575  108 IGRYPWHGALGRFGAADREKVEEAISLVGLKpLAHRL---VDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSALDIAHQV 184
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 2506233547 186 KVLALTERLVGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNVI 228
Cdd:PRK10575  185 DVLALVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMI 227
fecE PRK11231
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;
18-235 1.08e-15

Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;


Pssm-ID: 183044 [Multi-domain]  Cd Length: 255  Bit Score: 74.28  E-value: 1.08e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  18 EKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRATDLGRVFQDPMrgTAADM 97
Cdd:PRK11231   14 TKRILNDLSLSLPTGKITALIGPNGCGKSTLLKCFARLLTPQSGTVFLGDKPISMLSSRQLARRLALLPQHHL--TPEGI 91
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  98 QIVENLALaarrGESRGLS-WG-ITRDERASYRERLAelDLGLEERLTSKVGLLSGGQRQALTLLMAILKKPKLLLLDEH 175
Cdd:PRK11231   92 TVRELVAY----GRSPWLSlWGrLSAEDNARVNQAME--QTRINHLADRRLTDLSGGQRQRAFLAMVLAQDTPVVLLDEP 165
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 176 TAALDPKTASKVLALTERLVGEhGLTTLMVTHNMNDAIRLGNRLIMMHEGNVIFDARDDE 235
Cdd:PRK11231  166 TTYLDINHQVELMRLMRELNTQ-GKTVVTVLHDLNQASRYCDHLVVLANGHVMAQGTPEE 224
cbiO PRK13642
energy-coupling factor transporter ATPase;
7-235 1.12e-15

energy-coupling factor transporter ATPase;


Pssm-ID: 184202 [Multi-domain]  Cd Length: 277  Bit Score: 74.74  E-value: 1.12e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   7 VTKTFNKSTVNEkpaLTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRATDLGRVF 86
Cdd:PRK13642   11 VFKYEKESDVNQ---LNGVSFSITKGEWVSIIGQNGSGKSTTARLIDGLFEEFEGKVKIDGELLTAENVWNLRRKIGMVF 87
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  87 QDPmrgtaaDMQIV-----ENLALAARrgesrglSWGITRDERASyRERLAELDLGLEERLTSKVGLLSGGQRQALTLLM 161
Cdd:PRK13642   88 QNP------DNQFVgatveDDVAFGME-------NQGIPREEMIK-RVDEALLAVNMLDFKTREPARLSGGQKQRVAVAG 153
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2506233547 162 AILKKPKLLLLDEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIRlGNRLIMMHEGNVIFDARDDE 235
Cdd:PRK13642  154 IIALRPEIIILDESTSMLDPTGRQEIMRVIHEIKEKYQLTVLSITHDLDEAAS-SDRILVMKAGEIIKEAAPSE 226
BtuD COG4138
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism]; ...
22-229 1.75e-15

ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism];


Pssm-ID: 443313 [Multi-domain]  Cd Length: 248  Bit Score: 73.72  E-value: 1.75e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  22 LTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVfaLDG-GQVILDGRDVSRLPehrrATDLGRvfqdpMRG-------T 93
Cdd:COG4138    12 LGPISAQVNAGELIHLIGPNGAGKSTLLARMAGL--LPGqGEILLNGRPLSDWS----AAELAR-----HRAylsqqqsP 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  94 AADMQIVENLALAARRGESrglswgitrdeRASYRERLAEL--DLGLEERLTSKVGLLSGGQRQ----ALTLLM---AIL 164
Cdd:COG4138    81 PFAMPVFQYLALHQPAGAS-----------SEAVEQLLAQLaeALGLEDKLSRPLTQLSGGEWQrvrlAAVLLQvwpTIN 149
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2506233547 165 KKPKLLLLDEHTAALDPKTASKVLALTERLVgEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNVIF 229
Cdd:COG4138   150 PEGQLLLLDEPMNSLDVAQQAALDRLLRELC-QQGITVVMSSHDLNHTLRHADRVWLLKQGKLVA 213
cbiO PRK13649
energy-coupling factor transporter ATPase;
4-228 2.16e-15

energy-coupling factor transporter ATPase;


Pssm-ID: 184208 [Multi-domain]  Cd Length: 280  Bit Score: 74.01  E-value: 2.16e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   4 LKGVTKTFNKSTVNEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRATDL- 82
Cdd:PRK13649    5 LQNVSYTYQAGTPFEGRALFDVNLTIEDGSYTAFIGHTGSGKSTIMQLLNGLHVPTQGSVRVDDTLITSTSKNKDIKQIr 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  83 ---GRVFQDPmRGTAADMQIVENLALAARrgesrglSWGITRDE-RASYRERLAEldLGLEERLTSKVGL-LSGGQRQAL 157
Cdd:PRK13649   85 kkvGLVFQFP-ESQLFEETVLKDVAFGPQ-------NFGVSQEEaEALAREKLAL--VGISESLFEKNPFeLSGGQMRRV 154
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2506233547 158 TLLMAILKKPKLLLLDEHTAALDPKTASKVLALTERLvGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNVI 228
Cdd:PRK13649  155 AIAGILAMEPKILVLDEPTAGLDPKGRKELMTLFKKL-HQSGMTIVLVTHLMDDVANYADFVYVLEKGKLV 224
ABC_MTABC3_MDL1_MDL2 cd03249
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ...
3-228 4.19e-15

ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.


Pssm-ID: 213216 [Multi-domain]  Cd Length: 238  Bit Score: 72.57  E-value: 4.19e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   3 VLKGVTktFNKSTVNEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRATDL 82
Cdd:cd03249     2 EFKNVS--FRYPSRPDVPILKGLSLTIPPGKTVALVGSSGCGKSTVVSLLERFYDPTSGEILLDGVDIRDLNLRWLRSQI 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  83 GRVFQDPmrgTAADMQIVENLALAARRGESrglswgiTRDERASyreRLAELD---LGLEERLTSKVG----LLSGGQRQ 155
Cdd:cd03249    80 GLVSQEP---VLFDGTIAENIRYGKPDATD-------EEVEEAA---KKANIHdfiMSLPDGYDTLVGergsQLSGGQKQ 146
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2506233547 156 ALTLLMAILKKPKLLLLDEHTAALDPKTASKVLALTERLVGehGLTTLMVTHNMNdAIRLGNRLIMMHEGNVI 228
Cdd:cd03249   147 RIAIARALLRNPKILLLDEATSALDAESEKLVQEALDRAMK--GRTTIVIAHRLS-TIRNADLIAVLQNGQVV 216
cbiO PRK13640
energy-coupling factor transporter ATPase;
5-228 5.98e-15

energy-coupling factor transporter ATPase;


Pssm-ID: 184200 [Multi-domain]  Cd Length: 282  Bit Score: 72.91  E-value: 5.98e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   5 KGVTKTFNKStvnEKPALTGVDLHLEPGDFVTVIGGNGAGKST---LLNSIAGVFALDGGQVILDGRDVSRLPEHRRATD 81
Cdd:PRK13640    9 KHVSFTYPDS---KKPALNDISFSIPRGSWTALIGHNGSGKSTiskLINGLLLPDDNPNSKITVDGITLTAKTVWDIREK 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  82 LGRVFQDPmrgtaaDMQIV-----ENLALAArrgESRGLSwgitRDERASYRERLAElDLGLEERLTSKVGLLSGGQRQA 156
Cdd:PRK13640   86 VGIVFQNP------DNQFVgatvgDDVAFGL---ENRAVP----RPEMIKIVRDVLA-DVGMLDYIDSEPANLSGGQKQR 151
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2506233547 157 LTLLMAILKKPKLLLLDEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIrLGNRLIMMHEGNVI 228
Cdd:PRK13640  152 VAIAGILAVEPKIIILDESTSMLDPAGKEQILKLIRKLKKKNNLTVISITHDIDEAN-MADQVLVLDDGKLL 222
modC PRK11144
molybdenum ABC transporter ATP-binding protein ModC;
25-228 9.34e-15

molybdenum ABC transporter ATP-binding protein ModC;


Pssm-ID: 182993 [Multi-domain]  Cd Length: 352  Bit Score: 72.98  E-value: 9.34e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  25 VDLHLePGDFVTVI-GGNGAGKSTLLNSIAGVFALDGGQVILDGR---DVSR---LPEHRRatDLGRVFQDpmrgtaadm 97
Cdd:PRK11144   17 VNLTL-PAQGITAIfGRSGAGKTSLINAISGLTRPQKGRIVLNGRvlfDAEKgicLPPEKR--RIGYVFQD--------- 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  98 qivenlalaAR-------RGEsrgLSWGITRDERASYrERLAELdLGLEERLTSKVGLLSGG--QRQA-----LT----L 159
Cdd:PRK11144   85 ---------ARlfphykvRGN---LRYGMAKSMVAQF-DKIVAL-LGIEPLLDRYPGSLSGGekQRVAigralLTapelL 150
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2506233547 160 LMailkkpkllllDEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNVI 228
Cdd:PRK11144  151 LM-----------DEPLASLDLPRKRELLPYLERLAREINIPILYVSHSLDEILRLADRVVVLEQGKVK 208
PRK10070 PRK10070
proline/glycine betaine ABC transporter ATP-binding protein ProV;
4-248 1.06e-14

proline/glycine betaine ABC transporter ATP-binding protein ProV;


Pssm-ID: 182221 [Multi-domain]  Cd Length: 400  Bit Score: 73.14  E-value: 1.06e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   4 LKGVTKTFNKSTVNEKPALT-GV---DLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHR-- 77
Cdd:PRK10070   22 FKYIEQGLSKEQILEKTGLSlGVkdaSLAIEEGEIFVIMGLSGSGKSTMVRLLNRLIEPTRGQVLIDGVDIAKISDAElr 101
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  78 --RATDLGRVFQDpmRGTAADMQIVENLALAARRGesrglswGITRDERasyRERL--AELDLGLEERLTSKVGLLSGGQ 153
Cdd:PRK10070  102 evRRKKIAMVFQS--FALMPHMTVLDNTAFGMELA-------GINAEER---REKAldALRQVGLENYAHSYPDELSGGM 169
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 154 RQALTLLMAILKKPKLLLLDEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNVIFDARD 233
Cdd:PRK10070  170 RQRVGLARALAINPDILLMDEAFSALDPLIRTEMQDELVKLQAKHQRTIVFISHDLDEAMRIGDRIAIMQNGEVVQVGTP 249
                         250
                  ....*....|....*
gi 2506233547 234 DEKRRLRVHDLLQKF 248
Cdd:PRK10070  250 DEILNNPANDYVRTF 264
nikE PRK10419
nickel ABC transporter ATP-binding protein NikE;
22-228 1.54e-14

nickel ABC transporter ATP-binding protein NikE;


Pssm-ID: 236689 [Multi-domain]  Cd Length: 268  Bit Score: 71.26  E-value: 1.54e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  22 LTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRAT---DLGRVFQDPMRGTAADMQ 98
Cdd:PRK10419   28 LNNVSLSLKSGETVALLGRSGCGKSTLARLLVGLESPSQGNVSWRGEPLAKLNRAQRKAfrrDIQMVFQDSISAVNPRKT 107
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  99 IVENLALAARRgesrglswgITRDERASYRERLAEL--DLGLEERLTSKV-GLLSGGQRQALTLLMAILKKPKLLLLDEH 175
Cdd:PRK10419  108 VREIIREPLRH---------LLSLDKAERLARASEMlrAVDLDDSVLDKRpPQLSGGQLQRVCLARALAVEPKLLILDEA 178
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2506233547 176 TAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNVI 228
Cdd:PRK10419  179 VSNLDLVLQAGVIRLLKKLQQQFGTACLFITHDLRLVERFCQRVMVMDNGQIV 231
cbiO PRK13643
energy-coupling factor transporter ATPase;
1-228 1.72e-14

energy-coupling factor transporter ATPase;


Pssm-ID: 184203 [Multi-domain]  Cd Length: 288  Bit Score: 71.69  E-value: 1.72e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   1 MLVLKGVTKTFNKSTVNEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRAT 80
Cdd:PRK13643    1 MIKFEKVNYTYQPNSPFASRALFDIDLEVKKGSYTALIGHTGSGKSTLLQHLNGLLQPTEGKVTVGDIVVSSTSKQKEIK 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  81 ----DLGRVFQDPmRGTAADMQIVENLALAARrgesrglSWGITRDERASYRERLAELdLGLEERLTSKVGL-LSGGQRQ 155
Cdd:PRK13643   81 pvrkKVGVVFQFP-ESQLFEETVLKDVAFGPQ-------NFGIPKEKAEKIAAEKLEM-VGLADEFWEKSPFeLSGGQMR 151
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2506233547 156 ALTLLMAILKKPKLLLLDEHTAALDPKTASKVLALTERlVGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNVI 228
Cdd:PRK13643  152 RVAIAGILAMEPEVLVLDEPTAGLDPKARIEMMQLFES-IHQSGQTVVLVTHLMDDVADYADYVYLLEKGHII 223
PRK14271 PRK14271
phosphate ABC transporter ATP-binding protein; Provisional
19-228 3.77e-14

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172759 [Multi-domain]  Cd Length: 276  Bit Score: 70.51  E-value: 3.77e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  19 KPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVF-----------ALDGGQVILDGRDVSrlpEHRRAtdLGRVFQ 87
Cdd:PRK14271   34 KTVLDQVSMGFPARAVTSLMGPTGSGKTTFLRTLNRMNdkvsgyrysgdVLLGGRSIFNYRDVL---EFRRR--VGMLFQ 108
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  88 DPmrgTAADMQIVENLALAAR------RGESRGLSwgitrderasyRERLAELDL--GLEERLTSKVGLLSGGQRQALTL 159
Cdd:PRK14271  109 RP---NPFPMSIMDNVLAGVRahklvpRKEFRGVA-----------QARLTEVGLwdAVKDRLSDSPFRLSGGQQQLLCL 174
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2506233547 160 LMAILKKPKLLLLDEHTAALDPKTASKVLALTERLVGEhgLTTLMVTHNMNDAIRLGNRLIMMHEGNVI 228
Cdd:PRK14271  175 ARTLAVNPEVLLLDEPTSALDPTTTEKIEEFIRSLADR--LTVIIVTHNLAQAARISDRAALFFDGRLV 241
ArtP COG4161
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];
4-228 4.23e-14

ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443326 [Multi-domain]  Cd Length: 242  Bit Score: 69.66  E-value: 4.23e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   4 LKGVTKTFNKStvnekPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNsiagVFAL----DGGQVILDGR--DVSRLPEHR 77
Cdd:COG4161     5 LKNINCFYGSH-----QALFDINLECPSGETLVLLGPSGAGKSSLLR----VLNLletpDSGQLNIAGHqfDFSQKPSEK 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  78 RATDL----GRVFQD----PmrgtaaDMQIVENLALAARRgeSRGLSWGITRDERASYRERLaeldlgleeRLTSKVG-- 147
Cdd:COG4161    76 AIRLLrqkvGMVFQQynlwP------HLTVMENLIEAPCK--VLGLSKEQAREKAMKLLARL---------RLTDKADrf 138
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 148 --LLSGGQRQALTLLMAILKKPKLLLLDEHTAALDPKTASKVLALTERLvGEHGLTTLMVTHNMNDAIRLGNRLIMMHEG 225
Cdd:COG4161   139 plHLSGGQQQRVAIARALMMEPQVLLFDEPTAALDPEITAQVVEIIREL-SQTGITQVIVTHEVEFARKVASQVVYMEKG 217

                  ...
gi 2506233547 226 NVI 228
Cdd:COG4161   218 RII 220
ABCG_EPDR cd03213
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ...
2-229 4.75e-14

Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.


Pssm-ID: 213180 [Multi-domain]  Cd Length: 194  Bit Score: 68.73  E-value: 4.75e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   2 LVLKGVTKTFNKSTVN-EKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAG--VFALDGGQVILDGRDVSRLPEHRR 78
Cdd:cd03213     4 LSFRNLTVTVKSSPSKsGKQLLKNVSGKAKPGELTAIMGPSGAGKSTLLNALAGrrTGLGVSGEVLINGRPLDKRSFRKI 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  79 atdLGRVFQDPMrgTAADMQIVENLALAAR-RGesrglswgitrderasyrerlaeldlgleerltskvglLSGGQRQAL 157
Cdd:cd03213    84 ---IGYVPQDDI--LHPTLTVRETLMFAAKlRG--------------------------------------LSGGERKRV 120
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2506233547 158 TLLMAILKKPKLLLLDEHTAALDPKTASKVLALTERLvGEHGLTTLMVTHN-MNDAIRLGNRLIMMHEGNVIF 229
Cdd:cd03213   121 SIALELVSNPSLLFLDEPTSGLDSSSALQVMSLLRRL-ADTGRTIICSIHQpSSEIFELFDKLLLLSQGRVIY 192
PRK15439 PRK15439
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
1-229 7.58e-14

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional


Pssm-ID: 185336 [Multi-domain]  Cd Length: 510  Bit Score: 70.85  E-value: 7.58e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   1 MLVLKGVTKTFnkSTVnekPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRL-PEHRRA 79
Cdd:PRK15439   11 LLCARSISKQY--SGV---EVLKGIDFTLHAGEVHALLGGNGAGKSTLMKIIAGIVPPDSGTLEIGGNPCARLtPAKAHQ 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  80 TDLGRVFQDPMrgTAADMQIVENLALaarrgesrglswGITRDERASyrERLAEL--DLGLEERLTSKVGLLSGGQRQAL 157
Cdd:PRK15439   86 LGIYLVPQEPL--LFPNLSVKENILF------------GLPKRQASM--QKMKQLlaALGCQLDLDSSAGSLEVADRQIV 149
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2506233547 158 TLLMAILKKPKLLLLDEHTAALDPktaskvlALTERLVG------EHGLTTLMVTHNMNDAIRLGNRLIMMHEGNVIF 229
Cdd:PRK15439  150 EILRGLMRDSRILILDEPTASLTP-------AETERLFSrirellAQGVGIVFISHKLPEIRQLADRISVMRDGTIAL 220
PRK15079 PRK15079
oligopeptide ABC transporter ATP-binding protein OppF; Provisional
21-235 7.81e-14

oligopeptide ABC transporter ATP-binding protein OppF; Provisional


Pssm-ID: 185037 [Multi-domain]  Cd Length: 331  Bit Score: 70.12  E-value: 7.81e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  21 ALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRL-PEHRRAT--DLGRVFQDPM-----RG 92
Cdd:PRK15079   36 AVDGVTLRLYEGETLGVVGESGCGKSTFARAIIGLVKATDGEVAWLGKDLLGMkDDEWRAVrsDIQMIFQDPLaslnpRM 115
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  93 TAADMqIVENLalaarrgesRGLSWGITRDErasYRERLAELDLgleerltsKVGLL-----------SGGQRQALTLLM 161
Cdd:PRK15079  116 TIGEI-IAEPL---------RTYHPKLSRQE---VKDRVKAMML--------KVGLLpnlinryphefSGGQCQRIGIAR 174
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2506233547 162 AILKKPKLLLLDEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNVIFDARDDE 235
Cdd:PRK15079  175 ALILEPKLIICDEPVSALDVSIQAQVVNLLQQLQREMGLSLIFIAHDLAVVKHISDRVLVMYLGHAVELGTYDE 248
3a01208 TIGR00958
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]
18-227 8.23e-14

Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273363 [Multi-domain]  Cd Length: 711  Bit Score: 70.91  E-value: 8.23e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  18 EKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRATDLGRVFQDP--MRGTaa 95
Cdd:TIGR00958 493 DVPVLKGLTFTLHPGEVVALVGPSGSGKSTVAALLQNLYQPTGGQVLLDGVPLVQYDHHYLHRQVALVGQEPvlFSGS-- 570
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  96 dmqIVENLALaarrgesrGLSWGITRDERASYRERLA-----ELDLGLEERLTSKVGLLSGGQRQALTLLMAILKKPKLL 170
Cdd:TIGR00958 571 ---VRENIAY--------GLTDTPDEEIMAAAKAANAhdfimEFPNGYDTEVGEKGSQLSGGQKQRIAIARALVRKPRVL 639
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2506233547 171 LLDEHTAALDpktaskvlALTERLVGE----HGLTTLMVTHNMNdAIRLGNRLIMMHEGNV 227
Cdd:TIGR00958 640 ILDEATSALD--------AECEQLLQEsrsrASRTVLLIAHRLS-TVERADQILVLKKGSV 691
Uup COG0488
ATPase components of ABC transporters with duplicated ATPase domains [General function ...
4-154 8.54e-14

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];


Pssm-ID: 440254 [Multi-domain]  Cd Length: 520  Bit Score: 70.48  E-value: 8.54e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   4 LKGVTKTFNKstvneKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGR-DVSRLPEHRRATDL 82
Cdd:COG0488     1 LENLSKSFGG-----RPLLDDVSLSINPGDRIGLVGRNGAGKSTLLKILAGELEPDSGEVSIPKGlRIGYLPQEPPLDDD 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  83 GRVFQDPMRGTAADMQIVENLALAARRGESRGLSWgitrDERASYRERLAELD--------------LGLEER-LTSKVG 147
Cdd:COG0488    76 LTVLDTVLDGDAELRALEAELEELEAKLAEPDEDL----ERLAELQEEFEALGgweaearaeeilsgLGFPEEdLDRPVS 151

                  ....*..
gi 2506233547 148 LLSGGQR 154
Cdd:COG0488   152 ELSGGWR 158
cbiO PRK13641
energy-coupling factor transporter ATPase;
5-228 1.04e-13

energy-coupling factor transporter ATPase;


Pssm-ID: 237456 [Multi-domain]  Cd Length: 287  Bit Score: 69.47  E-value: 1.04e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   5 KGVTKTFNKSTVNEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVS------RLPEHRR 78
Cdd:PRK13641    6 ENVDYIYSPGTPMEKKGLDNISFELEEGSFVALVGHTGSGKSTLMQHFNALLKPSSGTITIAGYHITpetgnkNLKKLRK 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  79 ATDLgrVFQDPmrgtaaDMQIVENLALaaRRGESRGLSWGITRDERasyRERLAEL--DLGLEERLTSKVGL-LSGGQ-- 153
Cdd:PRK13641   86 KVSL--VFQFP------EAQLFENTVL--KDVEFGPKNFGFSEDEA---KEKALKWlkKVGLSEDLISKSPFeLSGGQmr 152
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2506233547 154 RQALTLLMAIlkKPKLLLLDEHTAALDPKTASKVLALTERLVGEhGLTTLMVTHNMNDAIRLGNRLIMMHEGNVI 228
Cdd:PRK13641  153 RVAIAGVMAY--EPEILCLDEPAAGLDPEGRKEMMQLFKDYQKA-GHTVILVTHNMDDVAEYADDVLVLEHGKLI 224
ccmA TIGR01189
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein ...
17-207 1.23e-13

heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein encoded by ccmA in bacteria. An exception is, an arabidopsis protein. Quite likely this is encoded by an organelle. Bacterial c-type cytocromes are located on the periplasmic side of the cytoplasmic membrane. Several gene products encoded in a locus designated as 'ccm' are implicated in the transport and assembly of the functional cytochrome C. This cluster includes genes: ccmA;B;C;D;E;F;G and H. The posttranslational pathway includes the transport of heme moiety, the secretion of the apoprotein and the covalent attachment of the heme with the apoprotein. The proteins ccmA and B represent an ABC transporter; ccmC and D participate in heme transfer to ccmE, which function as a periplasmic heme chaperone. The presence of ccmF, G and H is suggested to be obligatory for the final functional assembly of cytochrome c. [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Other]


Pssm-ID: 273491 [Multi-domain]  Cd Length: 198  Bit Score: 67.77  E-value: 1.23e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  17 NEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRATDLGRVFQDPMRGtaaD 96
Cdd:TIGR01189  11 GERMLFEGLSFTLNAGEALQVTGPNGIGKTTLLRILAGLLRPDSGEVRWNGTPLAEQRDEPHENILYLGHLPGLKP---E 87
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  97 MQIVENLALAARrgesrglswgITRDERASYRERLAELDL-GLEERLtskVGLLSGGQRQALTLLMAILKKPKLLLLDEH 175
Cdd:TIGR01189  88 LSALENLHFWAA----------IHGGAQRTIEDALAAVGLtGFEDLP---AAQLSAGQQRRLALARLWLSRRPLWILDEP 154
                         170       180       190
                  ....*....|....*....|....*....|....*
gi 2506233547 176 TAALDPKTaskvLALTERLVGEH---GLTTLMVTH 207
Cdd:TIGR01189 155 TTALDKAG----VALLAGLLRAHlarGGIVLLTTH 185
ABCC_ATM1_transporter cd03253
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ...
18-228 1.84e-13

ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213220 [Multi-domain]  Cd Length: 236  Bit Score: 68.03  E-value: 1.84e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  18 EKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEH--RRAtdLGRVFQDPM----- 90
Cdd:cd03253    13 GRPVLKDVSFTIPAGKKVAIVGPSGSGKSTILRLLFRFYDVSSGSILIDGQDIREVTLDslRRA--IGVVPQDTVlfndt 90
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  91 --------RGTAADMQIVEnlalAARRGesrglswgitrderasyreRLAELDLGLEERLTSKVG----LLSGGQRQALT 158
Cdd:cd03253    91 igynirygRPDATDEEVIE----AAKAA-------------------QIHDKIMRFPDGYDTIVGerglKLSGGEKQRVA 147
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 159 LLMAILKKPKLLLLDEHTAALDPKTASKVLALTERLVGehGLTTLMVTHNMNDAIRlGNRLIMMHEGNVI 228
Cdd:cd03253   148 IARAILKNPPILLLDEATSALDTHTEREIQAALRDVSK--GRTTIVIAHRLSTIVN-ADKIIVLKDGRIV 214
ABC_FeS_Assembly cd03217
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of ...
16-91 2.10e-13

ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.


Pssm-ID: 213184 [Multi-domain]  Cd Length: 200  Bit Score: 67.17  E-value: 2.10e-13
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2506233547  16 VNEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGV--FALDGGQVILDGRDVSRLPEHRRA-TDLGRVFQDPMR 91
Cdd:cd03217    10 VGGKEILKGVNLTIKKGEVHALMGPNGSGKSTLAKTIMGHpkYEVTEGEILFKGEDITDLPPEERArLGIFLAFQYPPE 88
3a01204 TIGR00955
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ...
17-235 2.98e-13

The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273361 [Multi-domain]  Cd Length: 617  Bit Score: 68.92  E-value: 2.98e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  17 NEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALD---GGQVILDGRDVSRLPEHRRAtdlGRVFQD----P 89
Cdd:TIGR00955  36 PRKHLLKNVSGVAKPGELLAVMGSSGAGKTTLMNALAFRSPKGvkgSGSVLLNGMPIDAKEMRAIS---AYVQQDdlfiP 112
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  90 MRGTAADMQIVENLALAARrgesrglswgITRDERasyRERLAEL--DLGLEERLTSKVGL------LSGGQRQALTLLM 161
Cdd:TIGR00955 113 TLTVREHLMFQAHLRMPRR----------VTKKEK---RERVDEVlqALGLRKCANTRIGVpgrvkgLSGGERKRLAFAS 179
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2506233547 162 AILKKPKLLLLDEHTAALDPKTASKVLALTERLvGEHGLTTLMVTHNMNDAI-RLGNRLIMMHEGNVIFDARDDE 235
Cdd:TIGR00955 180 ELLTDPPLLFCDEPTSGLDSFMAYSVVQVLKGL-AQKGKTIICTIHQPSSELfELFDKIILMAEGRVAYLGSPDQ 253
artP PRK11124
arginine transporter ATP-binding subunit; Provisional
21-228 3.06e-13

arginine transporter ATP-binding subunit; Provisional


Pssm-ID: 182980 [Multi-domain]  Cd Length: 242  Bit Score: 67.35  E-value: 3.06e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  21 ALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGR--DVSRLP------EHRRatDLGRVFQD---- 88
Cdd:PRK11124   17 ALFDITLDCPQGETLVLLGPSGAGKSSLLRVLNLLEMPRSGTLNIAGNhfDFSKTPsdkairELRR--NVGMVFQQynlw 94
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  89 PmrgtaaDMQIVENLALAARRgeSRGLSwgitrdeRASYRERLAELDLGLeeRLTSKVGL----LSGGQRQALTLLMAIL 164
Cdd:PRK11124   95 P------HLTVQQNLIEAPCR--VLGLS-------KDQALARAEKLLERL--RLKPYADRfplhLSGGQQQRVAIARALM 157
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2506233547 165 KKPKLLLLDEHTAALDPKTASKVLALTERLvGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNVI 228
Cdd:PRK11124  158 MEPQVLLFDEPTAALDPEITAQIVSIIREL-AETGITQVIVTHEVEVARKTASRVVYMENGHIV 220
cbiO PRK13652
cobalt transporter ATP-binding subunit; Provisional
8-228 3.10e-13

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 172200 [Multi-domain]  Cd Length: 277  Bit Score: 67.91  E-value: 3.10e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   8 TKTFNKSTVNEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRATDLGRVFQ 87
Cdd:PRK13652    6 TRDLCYSYSGSKEALNNINFIAPRNSRIAVIGPNGAGKSTLFRHFNGILKPTSGSVLIRGEPITKENIREVRKFVGLVFQ 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  88 DPmrgtaaDMQIVENLAlaarrgeSRGLSWGITR----DERASYRERLAELDLGLEERLTSKVGLLSGGQRQALTLLMAI 163
Cdd:PRK13652   86 NP------DDQIFSPTV-------EQDIAFGPINlgldEETVAHRVSSALHMLGLEELRDRVPHHLSGGEKKRVAIAGVI 152
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2506233547 164 LKKPKLLLLDEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNVI 228
Cdd:PRK13652  153 AMEPQVLVLDEPTAGLDPQGVKELIDFLNDLPETYGMTVIFSTHQLDLVPEMADYIYVMDKGRIV 217
PRK14267 PRK14267
phosphate ABC transporter ATP-binding protein; Provisional
22-228 4.09e-13

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 184596 [Multi-domain]  Cd Length: 253  Bit Score: 67.17  E-value: 4.09e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  22 LTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDG-----GQVILDGRDVSRLP----EHRRatDLGRVFQDPmrG 92
Cdd:PRK14267   20 IKGVDLKIPQNGVFALMGPSGCGKSTLLRTFNRLLELNEearveGEVRLFGRNIYSPDvdpiEVRR--EVGMVFQYP--N 95
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  93 TAADMQIVENLALAARRGesrGLSWGITR-DERASYRERLAELDLGLEERLTSKVGLLSGGQRQALTLLMAILKKPKLLL 171
Cdd:PRK14267   96 PFPHLTIYDNVAIGVKLN---GLVKSKKElDERVEWALKKAALWDEVKDRLNDYPSNLSGGQRQRLVIARALAMKPKILL 172
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2506233547 172 LDEHTAALDPKTASKVLALTERLVGEhgLTTLMVTHNMNDAIRLGNRLIMMHEGNVI 228
Cdd:PRK14267  173 MDEPTANIDPVGTAKIEELLFELKKE--YTIVLVTHSPAQAARVSDYVAFLYLGKLI 227
PRK10790 PRK10790
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;
17-228 5.21e-13

SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;


Pssm-ID: 182733 [Multi-domain]  Cd Length: 592  Bit Score: 68.21  E-value: 5.21e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  17 NEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRATDLGRVFQDPMrgTAAD 96
Cdd:PRK10790  352 DDNLVLQNINLSVPSRGFVALVGHTGSGKSTLASLLMGYYPLTEGEIRLDGRPLSSLSHSVLRQGVAMVQQDPV--VLAD 429
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  97 mQIVENLALAarRGESRGLSWgitrdeRASYRERLAELDLGLEERLTSKVG----LLSGGQRQALTLLMAILKKPKLLLL 172
Cdd:PRK10790  430 -TFLANVTLG--RDISEEQVW------QALETVQLAELARSLPDGLYTPLGeqgnNLSVGQKQLLALARVLVQTPQILIL 500
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2506233547 173 DEHTAALDPKTASKVL-ALteRLVGEHglTTLMVTHNMNDAIRLGNRLIMMHEGNVI 228
Cdd:PRK10790  501 DEATANIDSGTEQAIQqAL--AAVREH--TTLVVIAHRLSTIVEADTILVLHRGQAV 553
PRK15112 PRK15112
peptide ABC transporter ATP-binding protein SapF;
1-255 7.51e-13

peptide ABC transporter ATP-binding protein SapF;


Pssm-ID: 185067 [Multi-domain]  Cd Length: 267  Bit Score: 66.74  E-value: 7.51e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   1 MLVLKGVTKTFNKST----VNEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEH 76
Cdd:PRK15112    4 LLEVRNLSKTFRYRTgwfrRQTVEAVKPLSFTLREGQTLAIIGENGSGKSTLAKMLAGMIEPTSGELLIDDHPLHFGDYS 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  77 RRATDLGRVFQDPMRGTAADMQIVENLALAARrgesrgLSWGITRDERA-SYRERLAELDLgLEERLTSKVGLLSGGQRQ 155
Cdd:PRK15112   84 YRSQRIRMIFQDPSTSLNPRQRISQILDFPLR------LNTDLEPEQREkQIIETLRQVGL-LPDHASYYPHMLAPGQKQ 156
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 156 ALTLLMAILKKPKLLLLDEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNVIFDARDDE 235
Cdd:PRK15112  157 RLGLARALILRPKVIIADEALASLDMSMRSQLINLMLELQEKQGISYIYVTQHLGMMKHISDQVLVMHQGEVVERGSTAD 236
                         250       260
                  ....*....|....*....|
gi 2506233547 236 KRRLRVHDLLQKFEEASGGE 255
Cdd:PRK15112  237 VLASPLHELTKRLIAGHFGE 256
PRK14246 PRK14246
phosphate ABC transporter ATP-binding protein; Provisional
5-228 8.35e-13

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172734 [Multi-domain]  Cd Length: 257  Bit Score: 66.22  E-value: 8.35e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   5 KGVTKTFNKST----VNEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDG------GQVILDGRDVSRLP 74
Cdd:PRK14246    5 KSAEDVFNISRlylyINDKAILKDITIKIPNNSIFGIMGPSGSGKSTLLKVLNRLIEIYDskikvdGKVLYFGKDIFQID 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  75 EHRRATDLGRVFQDPmrGTAADMQIVENLALAARrgesrglSWGIT--RDERASYRERLAELDLGLE--ERLTSKVGLLS 150
Cdd:PRK14246   85 AIKLRKEVGMVFQQP--NPFPHLSIYDNIAYPLK-------SHGIKekREIKKIVEECLRKVGLWKEvyDRLNSPASQLS 155
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2506233547 151 GGQRQALTLLMAILKKPKLLLLDEHTAALDPKTASKVLALTERLVGEhgLTTLMVTHNMNDAIRLGNRLIMMHEGNVI 228
Cdd:PRK14246  156 GGQQQRLTIARALALKPKVLLMDEPTSMIDIVNSQAIEKLITELKNE--IAIVIVSHNPQQVARVADYVAFLYNGELV 231
rim_protein TIGR01257
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...
4-227 9.07e-13

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]


Pssm-ID: 130324 [Multi-domain]  Cd Length: 2272  Bit Score: 68.12  E-value: 9.07e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547    4 LKGVTKTFNKSTvneKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRATdLG 83
Cdd:TIGR01257  931 VKNLVKIFEPSG---RPAVDRLNITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLVGGKDIETNLDAVRQS-LG 1006
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   84 RVFQDPMrgTAADMQIVENLALAArrgESRGLSWgitrDERASYRERLAElDLGLEERLTSKVGLLSGGQRQALTLLMAI 163
Cdd:TIGR01257 1007 MCPQHNI--LFHHLTVAEHILFYA---QLKGRSW----EEAQLEMEAMLE-DTGLHHKRNEEAQDLSGGMQRKLSVAIAF 1076
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2506233547  164 LKKPKLLLLDEHTAALDPKTASKVLALTerLVGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNV 227
Cdd:TIGR01257 1077 VGDAKVVVLDEPTSGVDPYSRRSIWDLL--LKYRSGRTIIMSTHHMDEADLLGDRIAIISQGRL 1138
PLN03232 PLN03232
ABC transporter C family member; Provisional
20-228 1.20e-12

ABC transporter C family member; Provisional


Pssm-ID: 215640 [Multi-domain]  Cd Length: 1495  Bit Score: 67.69  E-value: 1.20e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   20 PALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSR--LPEHRRAtdLGRVFQDPM--RGTaa 95
Cdd:PLN03232  1250 PVLHGLSFFVSPSEKVGVVGRTGAGKSSMLNALFRIVELEKGRIMIDDCDVAKfgLTDLRRV--LSIIPQSPVlfSGT-- 1325
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   96 dmqIVENLALAARRGESrGLsWGITrdERASYRERLAELDLGLEERLTSKVGLLSGGQRQALTLLMAILKKPKLLLLDEH 175
Cdd:PLN03232  1326 ---VRFNIDPFSEHNDA-DL-WEAL--ERAHIKDVIDRNPFGLDAEVSEGGENFSVGQRQLLSLARALLRRSKILVLDEA 1398
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 2506233547  176 TAALDPKTASkvlaLTERLVGEH--GLTTLMVTHNMNDAIRLgNRLIMMHEGNVI 228
Cdd:PLN03232  1399 TASVDVRTDS----LIQRTIREEfkSCTMLVIAHRLNTIIDC-DKILVLSSGQVL 1448
oppD PRK09473
oligopeptide transporter ATP-binding component; Provisional
21-225 1.36e-12

oligopeptide transporter ATP-binding component; Provisional


Pssm-ID: 181888 [Multi-domain]  Cd Length: 330  Bit Score: 66.29  E-value: 1.36e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  21 ALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDG---GQVILDGRDVSRLPEHR----RATDLGRVFQDPMRGT 93
Cdd:PRK09473   31 AVNDLNFSLRAGETLGIVGESGSGKSQTAFALMGLLAANGrigGSATFNGREILNLPEKElnklRAEQISMIFQDPMTSL 110
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  94 AADMQIVENLAlaarrgESRGLSWGITRDEraSYRERLAELD-LGLEE---RLTSKVGLLSGGQRQALTLLMAILKKPKL 169
Cdd:PRK09473  111 NPYMRVGEQLM------EVLMLHKGMSKAE--AFEESVRMLDaVKMPEarkRMKMYPHEFSGGMRQRVMIAMALLCRPKL 182
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2506233547 170 LLLDEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIRLGNRLIMMHEG 225
Cdd:PRK09473  183 LIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAG 238
PRK11174 PRK11174
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
21-211 1.45e-12

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed


Pssm-ID: 236870 [Multi-domain]  Cd Length: 588  Bit Score: 67.18  E-value: 1.45e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  21 ALTG-VDLHLEPGDFVTVIGGNGAGKSTLLNSIAGvFALDGGQVILDGRDVSRL-PEHRRATdLGRVFQDPM--RGTaad 96
Cdd:PRK11174  364 TLAGpLNFTLPAGQRIALVGPSGAGKTSLLNALLG-FLPYQGSLKINGIELRELdPESWRKH-LSWVGQNPQlpHGT--- 438
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  97 mqIVENLALAARRGESRGLSWGItrdERASYRERLAELDLGLEERLTSKVGLLSGGQRQALTLLMAILKKPKLLLLDEHT 176
Cdd:PRK11174  439 --LRDNVLLGNPDASDEQLQQAL---ENAWVSEFLPLLPQGLDTPIGDQAAGLSVGQAQRLALARALLQPCQLLLLDEPT 513
                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 2506233547 177 AALDPKTASKVL-ALTErlvGEHGLTTLMVTHNMND 211
Cdd:PRK11174  514 ASLDAHSEQLVMqALNA---ASRRQTTLMVTHQLED 546
ABCC_TAP cd03248
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; ...
4-227 1.74e-12

ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; TAP (Transporter Associated with Antigen Processing) is essential for peptide delivery from the cytosol into the lumen of the endoplasmic reticulum (ER), where these peptides are loaded on major histocompatibility complex (MHC) I molecules. Loaded MHC I leave the ER and display their antigenic cargo on the cell surface to cytotoxic T cells. Subsequently, virus-infected or malignantly transformed cells can be eliminated. TAP belongs to the large family of ATP-binding cassette (ABC) transporters, which translocate a vast variety of solutes across membranes.


Pssm-ID: 213215 [Multi-domain]  Cd Length: 226  Bit Score: 64.80  E-value: 1.74e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   4 LKGVTK----TFNKSTVNEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSrLPEHR-- 77
Cdd:cd03248     8 LKGIVKfqnvTFAYPTRPDTLVLQDVSFTLHPGEVTALVGPSGSGKSTVVALLENFYQPQGGQVLLDGKPIS-QYEHKyl 86
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  78 ---------RATDLGRVFQDPMR---GTAADMQIVEnlalAARRGESRGLswgitrderasyrerLAELDLGLEERLTSK 145
Cdd:cd03248    87 hskvslvgqEPVLFARSLQDNIAyglQSCSFECVKE----AAQKAHAHSF---------------ISELASGYDTEVGEK 147
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 146 VGLLSGGQRQALTLLMAILKKPKLLLLDEHTAALDPKTASKV-LALTErlvGEHGLTTLMVTHNMNdAIRLGNRLIMMHE 224
Cdd:cd03248   148 GSQLSGGQKQRVAIARALIRNPQVLILDEATSALDAESEQQVqQALYD---WPERRTVLVIAHRLS-TVERADQILVLDG 223

                  ...
gi 2506233547 225 GNV 227
Cdd:cd03248   224 GRI 226
PRK13536 PRK13536
nodulation factor ABC transporter ATP-binding protein NodI;
4-235 2.00e-12

nodulation factor ABC transporter ATP-binding protein NodI;


Pssm-ID: 237419 [Multi-domain]  Cd Length: 340  Bit Score: 66.01  E-value: 2.00e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   4 LKGVTKTFNkstvnEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRATdLG 83
Cdd:PRK13536   44 LAGVSKSYG-----DKAVVNGLSFTVASGECFGLLGPNGAGKSTIARMILGMTSPDAGKITVLGVPVPARARLARAR-IG 117
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  84 RVFQ----DPmrgtaaDMQIVENLALAARrgesrglSWGITRDERASYRERLAELdLGLEERLTSKVGLLSGGQRQALTL 159
Cdd:PRK13536  118 VVPQfdnlDL------EFTVRENLLVFGR-------YFGMSTREIEAVIPSLLEF-ARLESKADARVSDLSGGMKRRLTL 183
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2506233547 160 LMAILKKPKLLLLDEHTAALDPKtASKVLALTERLVGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNVIFDARDDE 235
Cdd:PRK13536  184 ARALINDPQLLILDEPTTGLDPH-ARHLIWERLRSLLARGKTILLTTHFMEEAERLCDRLCVLEAGRKIAEGRPHA 258
ABCC_cytochrome_bd cd03247
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ...
17-230 2.46e-12

ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.


Pssm-ID: 213214 [Multi-domain]  Cd Length: 178  Bit Score: 63.49  E-value: 2.46e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  17 NEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRATdLGRVFQDPMrgtAAD 96
Cdd:cd03247    13 QEQQVLKNLSLELKQGEKIALLGRSGSGKSTLLQLLTGDLKPQQGEITLDGVPVSDLEKALSSL-ISVLNQRPY---LFD 88
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  97 MQIVENLAlaaRRgesrglswgitrderasyrerlaeldlgleerltskvglLSGGQRQALTLLMAILKKPKLLLLDEHT 176
Cdd:cd03247    89 TTLRNNLG---RR---------------------------------------FSGGERQRLALARILLQDAPIVLLDEPT 126
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2506233547 177 AALDPKTASKVLalteRLVGEH--GLTTLMVTHNMNdAIRLGNRLIMMHEGNVIFD 230
Cdd:cd03247   127 VGLDPITERQLL----SLIFEVlkDKTLIWITHHLT-GIEHMDKILFLENGKIIMQ 177
nikD PRK10418
nickel transporter ATP-binding protein NikD; Provisional
19-228 3.35e-12

nickel transporter ATP-binding protein NikD; Provisional


Pssm-ID: 236688 [Multi-domain]  Cd Length: 254  Bit Score: 64.72  E-value: 3.35e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  19 KPALTGVDLHLEPGDFVTVIGGNGAGKS-TLLNSI----AGVFALdGGQVILDGRDVSrlPEHRRATDLGRVFQDPMRGt 93
Cdd:PRK10418   16 QPLVHGVSLTLQRGRVLALVGGSGSGKSlTCAAALgilpAGVRQT-AGRVLLDGKPVA--PCALRGRKIATIMQNPRSA- 91
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  94 aadMQIVENLALAARRgesRGLSWGITRDErASYRERLAELDLGLEERLTSKVGL-LSGGQRQALTLLMAILKKPKLLLL 172
Cdd:PRK10418   92 ---FNPLHTMHTHARE---TCLALGKPADD-ATLTAALEAVGLENAARVLKLYPFeMSGGMLQRMMIALALLCEAPFIIA 164
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2506233547 173 DEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNVI 228
Cdd:PRK10418  165 DEPTTDLDVVAQARILDLLESIVQKRALGMLLVTHDMGVVARLADDVAVMSHGRIV 220
PRK10261 PRK10261
glutathione transporter ATP-binding protein; Provisional
1-228 4.14e-12

glutathione transporter ATP-binding protein; Provisional


Pssm-ID: 182342 [Multi-domain]  Cd Length: 623  Bit Score: 65.65  E-value: 4.14e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   1 MLVLKGVTKTFNKSTvNEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDG-------RDVSRL 73
Cdd:PRK10261   12 VLAVENLNIAFMQEQ-QKIAAVRNLSFSLQRGETLAIVGESGSGKSVTALALMRLLEQAGGLVQCDKmllrrrsRQVIEL 90
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  74 PE-------HRRATDLGRVFQDPMRGTAADMQIVENLAlaarrgESRGLSWGITRDERASYRERLAELDLGLEER--LTS 144
Cdd:PRK10261   91 SEqsaaqmrHVRGADMAMIFQEPMTSLNPVFTVGEQIA------ESIRLHQGASREEAMVEAKRMLDQVRIPEAQtiLSR 164
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 145 KVGLLSGGQRQALTLLMAILKKPKLLLLDEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIRLGNRLIMMHE 224
Cdd:PRK10261  165 YPHQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQKEMSMGVIFITHDMGVVAEIADRVLVMYQ 244

                  ....
gi 2506233547 225 GNVI 228
Cdd:PRK10261  245 GEAV 248
type_I_sec_PrtD TIGR01842
type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in ...
18-239 4.25e-12

type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 200134 [Multi-domain]  Cd Length: 544  Bit Score: 65.45  E-value: 4.25e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  18 EKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRATDLGRVFQDP--MRGTAA 95
Cdd:TIGR01842 330 KKPTLRGISFSLQAGEALAIIGPSGSGKSTLARLIVGIWPPTSGSVRLDGADLKQWDRETFGKHIGYLPQDVelFPGTVA 409
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  96 dmqivENLAlaaRRGESrglswgiTRDERASYRERLA---ELDLGLEERLTSKVGL----LSGGQRQALTLLMAILKKPK 168
Cdd:TIGR01842 410 -----ENIA---RFGEN-------ADPEKIIEAAKLAgvhELILRLPDGYDTVIGPggatLSGGQRQRIALARALYGDPK 474
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2506233547 169 LLLLDEHTAALDPK----TASKVLALTERlvgehGLTTLMVTHNMNdAIRLGNRLIMMHEGNV-IFDARDDEKRRL 239
Cdd:TIGR01842 475 LVVLDEPNSNLDEEgeqaLANAIKALKAR-----GITVVVITHRPS-LLGCVDKILVLQDGRIaRFGERDEVLAKL 544
PRK10895 PRK10895
lipopolysaccharide ABC transporter ATP-binding protein; Provisional
25-228 4.41e-12

lipopolysaccharide ABC transporter ATP-binding protein; Provisional


Pssm-ID: 182817 [Multi-domain]  Cd Length: 241  Bit Score: 64.14  E-value: 4.41e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  25 VDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRA-TDLGRVFQDPmrGTAADMQIVENL 103
Cdd:PRK10895   22 VSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRDAGNIIIDDEDISLLPLHARArRGIGYLPQEA--SIFRRLSVYDNL 99
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 104 -ALAARRGEsrglswgITRDERASYRERLAElDLGLEERLTSKVGLLSGGQRQALTLLMAILKKPKLLLLDEHTAALDPK 182
Cdd:PRK10895  100 mAVLQIRDD-------LSAEQREDRANELME-EFHIEHLRDSMGQSLSGGERRRVEIARALAANPKFILLDEPFAGVDPI 171
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 2506233547 183 TASKVLALTERLvGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNVI 228
Cdd:PRK10895  172 SVIDIKRIIEHL-RDSGLGVLITDHNVRETLAVCERAYIVSQGHLI 216
PRK11176 PRK11176
lipid A ABC transporter ATP-binding protein/permease MsbA;
18-180 6.09e-12

lipid A ABC transporter ATP-binding protein/permease MsbA;


Pssm-ID: 183016 [Multi-domain]  Cd Length: 582  Bit Score: 65.04  E-value: 6.09e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  18 EKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVS--RLPEHRRATDLG----RVFQDpmr 91
Cdd:PRK11176  355 EVPALRNINFKIPAGKTVALVGRSGSGKSTIANLLTRFYDIDEGEILLDGHDLRdyTLASLRNQVALVsqnvHLFND--- 431
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  92 gtaadmQIVENLALAARRGESRGlswGITRDERASY-RERLAELDLGLEERLTSKVGLLSGGQRQALTLLMAILKKPKLL 170
Cdd:PRK11176  432 ------TIANNIAYARTEQYSRE---QIEEAARMAYaMDFINKMDNGLDTVIGENGVLLSGGQRQRIAIARALLRDSPIL 502
                         170
                  ....*....|
gi 2506233547 171 LLDEHTAALD 180
Cdd:PRK11176  503 ILDEATSALD 512
Uup COG0488
ATPase components of ABC transporters with duplicated ATPase domains [General function ...
1-162 1.21e-11

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];


Pssm-ID: 440254 [Multi-domain]  Cd Length: 520  Bit Score: 64.32  E-value: 1.21e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   1 MLVLKGVTKTFNkstvnEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILdGRDVSR--LPEHRR 78
Cdd:COG0488   315 VLELEGLSKSYG-----DKTLLDDLSLRIDRGDRIGLIGPNGAGKSTLLKLLAGELEPDSGTVKL-GETVKIgyFDQHQE 388
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  79 ATDLgrvfqdpmrgtaaDMQIVENLALAA---RRGESRGL--SWGITRDerasyrerlaeldlgleeRLTSKVGLLSGGQ 153
Cdd:COG0488   389 ELDP-------------DKTVLDELRDGApggTEQEVRGYlgRFLFSGD------------------DAFKPVGVLSGGE 437
                         170
                  ....*....|.
gi 2506233547 154 RQ--ALTLLMA 162
Cdd:COG0488   438 KArlALAKLLL 448
PRK13539 PRK13539
cytochrome c biogenesis protein CcmA; Provisional
17-208 1.24e-11

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 237421 [Multi-domain]  Cd Length: 207  Bit Score: 62.20  E-value: 1.24e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  17 NEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDvSRLPEHR-RATDLGRvfQDPMRGTaa 95
Cdd:PRK13539   13 GGRVLFSGLSFTLAAGEALVLTGPNGSGKTTLLRLIAGLLPPAAGTIKLDGGD-IDDPDVAeACHYLGH--RNAMKPA-- 87
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  96 dMQIVENLALAARrgesrglswgITRDERASYRERLAELDLGLEERLtsKVGLLSGGQRQALTLLMAILKKPKLLLLDEH 175
Cdd:PRK13539   88 -LTVAENLEFWAA----------FLGGEELDIAAALEAVGLAPLAHL--PFGYLSAGQKRRVALARLLVSNRPIWILDEP 154
                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 2506233547 176 TAALDpkTASKvlALTERLVGEH---GLTTLMVTHN 208
Cdd:PRK13539  155 TAALD--AAAV--ALFAELIRAHlaqGGIVIAATHI 186
PRK11160 PRK11160
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
17-228 1.30e-11

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed


Pssm-ID: 236865 [Multi-domain]  Cd Length: 574  Bit Score: 64.08  E-value: 1.30e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  17 NEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEH--RRATDL--GRV--FQDPM 90
Cdd:PRK11160  351 QPQPVLKGLSLQIKAGEKVALLGRTGCGKSTLLQLLTRAWDPQQGEILLNGQPIADYSEAalRQAISVvsQRVhlFSATL 430
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  91 RgtaadmqivENLALAArrgesrglswgitrdERASyRERLAEL--DLGLEERLTSKVGL----------LSGGQRQALT 158
Cdd:PRK11160  431 R---------DNLLLAA---------------PNAS-DEALIEVlqQVGLEKLLEDDKGLnawlgeggrqLSGGEQRRLG 485
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2506233547 159 LLMAILKKPKLLLLDEHTAALDPKTASKVLALTErlvgEH--GLTTLMVTHNMNdAIRLGNRLIMMHEGNVI 228
Cdd:PRK11160  486 IARALLHDAPLLLLDEPTEGLDAETERQILELLA----EHaqNKTVLMITHRLT-GLEQFDRICVMDNGQII 552
xylG TIGR02633
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ...
1-225 1.34e-11

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 131681 [Multi-domain]  Cd Length: 500  Bit Score: 64.08  E-value: 1.34e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   1 MLVLKGVTKTFNKSTvnekpALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDG--GQVILDGRDVSrlPEHRR 78
Cdd:TIGR02633   1 LLEMKGIVKTFGGVK-----ALDGIDLEVRPGECVGLCGENGAGKSTLMKILSGVYPHGTwdGEIYWSGSPLK--ASNIR 73
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  79 ATD---LGRVFQDPMrgTAADMQIVENLALaarrGESRGLSWGITRDERASYR--ERLAELDLGLEErLTSKVGLLSGGQ 153
Cdd:TIGR02633  74 DTEragIVIIHQELT--LVPELSVAENIFL----GNEITLPGGRMAYNAMYLRakNLLRELQLDADN-VTRPVGDYGGGQ 146
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2506233547 154 RQALTLLMAILKKPKLLLLDEHTAALDPKTASKVLALTERLvGEHGLTTLMVTHNMNDAIRLGNRLIMMHEG 225
Cdd:TIGR02633 147 QQLVEIAKALNKQARLLILDEPSSSLTEKETEILLDIIRDL-KAHGVACVYISHKLNEVKAVCDTICVIRDG 217
PRK11000 PRK11000
maltose/maltodextrin ABC transporter ATP-binding protein MalK;
4-227 1.64e-11

maltose/maltodextrin ABC transporter ATP-binding protein MalK;


Pssm-ID: 182893 [Multi-domain]  Cd Length: 369  Bit Score: 63.51  E-value: 1.64e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   4 LKGVTKTFNKSTVNEKpaltgVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRAtdLG 83
Cdd:PRK11000    6 LRNVTKAYGDVVISKD-----INLDIHEGEFVVFVGPSGCGKSTLLRMIAGLEDITSGDLFIGEKRMNDVPPAERG--VG 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  84 RVFQD----PMRGTAADMQIveNLALAarrgesrglswGITRDERASYRERLAELdLGLEERLTSKVGLLSGGQRQALTL 159
Cdd:PRK11000   79 MVFQSyalyPHLSVAENMSF--GLKLA-----------GAKKEEINQRVNQVAEV-LQLAHLLDRKPKALSGGQRQRVAI 144
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 160 LMAILKKPKLLLLDEHTAALDpkTASKVLALTE--RLVGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNV 227
Cdd:PRK11000  145 GRTLVAEPSVFLLDEPLSNLD--AALRVQMRIEisRLHKRLGRTMIYVTHDQVEAMTLADKIVVLDAGRV 212
ABCC_MRP_domain1 cd03250
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ...
2-225 1.69e-11

ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213217 [Multi-domain]  Cd Length: 204  Bit Score: 61.72  E-value: 1.69e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   2 LVLKGVTKTFNKSTVNEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRdvsrlpehrratd 81
Cdd:cd03250     1 ISVEDASFTWDSGEQETSFTLKDINLEVPKGELVAIVGPVGSGKSSLLSALLGELEKLSGSVSVPGS------------- 67
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  82 LGRVFQDP--MRGTaadmqIVENLALAARRGESRglswgitrderasYRE---------RLAELDLGLE----ERLTSkv 146
Cdd:cd03250    68 IAYVSQEPwiQNGT-----IRENILFGKPFDEER-------------YEKvikacalepDLEILPDGDLteigEKGIN-- 127
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 147 glLSGGQRQALTLLMAILKKPKLLLLDEHTAALDPKTASKvlaLTERLVGEHGL---TTLMVTHNMnDAIRLGNRLIMMH 223
Cdd:cd03250   128 --LSGGQKQRISLARAVYSDADIYLLDDPLSAVDAHVGRH---IFENCILGLLLnnkTRILVTHQL-QLLPHADQIVVLD 201

                  ..
gi 2506233547 224 EG 225
Cdd:cd03250   202 NG 203
araG PRK11288
L-arabinose ABC transporter ATP-binding protein AraG;
2-225 1.88e-11

L-arabinose ABC transporter ATP-binding protein AraG;


Pssm-ID: 183077 [Multi-domain]  Cd Length: 501  Bit Score: 63.78  E-value: 1.88e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   2 LVLKGVTKTFnkstvnekP---ALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVsRLPEHRR 78
Cdd:PRK11288    5 LSFDGIGKTF--------PgvkALDDISFDCRAGQVHALMGENGAGKSTLLKILSGNYQPDAGSILIDGQEM-RFASTTA 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  79 ATDLGR--VFQD----PmrgtaaDMQIVENL---ALAARRGesrglsWGITRDERASYRERLAELDLGLEERltSKVGLL 149
Cdd:PRK11288   76 ALAAGVaiIYQElhlvP------EMTVAENLylgQLPHKGG------IVNRRLLNYEAREQLEHLGVDIDPD--TPLKYL 141
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2506233547 150 SGGQRQALTLLMAILKKPKLLLLDEHTAALDPKTASKVLALTERLVGEhGLTTLMVTHNMNDAIRLGNRLIMMHEG 225
Cdd:PRK11288  142 SIGQRQMVEIAKALARNARVIAFDEPTSSLSAREIEQLFRVIRELRAE-GRVILYVSHRMEEIFALCDAITVFKDG 216
3a01205 TIGR00956
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
6-229 1.91e-11

Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273362 [Multi-domain]  Cd Length: 1394  Bit Score: 63.97  E-value: 1.91e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547    6 GVTKTFNKSTVNEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGV---FALD-GGQVILDGRDVSRLPEHRRAtd 81
Cdd:TIGR00956   61 GFRKLKKFRDTKTFDILKPMDGLIKPGELTVVLGRPGSGCSTLLKTIASNtdgFHIGvEGVITYDGITPEEIKKHYRG-- 138
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   82 lgrvfqDPMRGTAAD-----MQIVENLALAAR-RG-ESRGLswGITRDERASYRERLAELDLGLEERLTSKVGL-----L 149
Cdd:TIGR00956  139 ------DVVYNAETDvhfphLTVGETLDFAARcKTpQNRPD--GVSREEYAKHIADVYMATYGLSHTRNTKVGNdfvrgV 210
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  150 SGGQRQALTLLMAILKKPKLLLLDEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMN-DAIRLGNRLIMMHEGNVI 228
Cdd:TIGR00956  211 SGGERKRVSIAEASLGGAKIQCWDNATRGLDSATALEFIRALKTSANILDTTPLVAIYQCSqDAYELFDKVIVLYEGYQI 290

                   .
gi 2506233547  229 F 229
Cdd:TIGR00956  291 Y 291
cbiO PRK13647
cobalt transporter ATP-binding subunit; Provisional
21-228 2.18e-11

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237457 [Multi-domain]  Cd Length: 274  Bit Score: 62.45  E-value: 2.18e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  21 ALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRATDLGRVFQDPMRGTAAdMQIV 100
Cdd:PRK13647   20 ALKGLSLSIPEGSKTALLGPNGAGKSTLLLHLNGIYLPQRGRVKVMGREVNAENEKWVRSKVGLVFQDPDDQVFS-STVW 98
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 101 ENLALAARrgesrglSWGITRDERASyRERLAELDLGLEERLTSKVGLLSGGQRQALTLLMAILKKPKLLLLDEHTAALD 180
Cdd:PRK13647   99 DDVAFGPV-------NMGLDKDEVER-RVEEALKAVRMWDFRDKPPYHLSYGQKKRVAIAGVLAMDPDVIVLDEPMAYLD 170
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 2506233547 181 PKTASKVLALTERLVGEhGLTTLMVTHNMNDAIRLGNRLIMMHEGNVI 228
Cdd:PRK13647  171 PRGQETLMEILDRLHNQ-GKTVIVATHDVDLAAEWADQVIVLKEGRVL 217
dppD PRK11022
dipeptide transporter ATP-binding subunit; Provisional
17-228 2.20e-11

dipeptide transporter ATP-binding subunit; Provisional


Pssm-ID: 182906 [Multi-domain]  Cd Length: 326  Bit Score: 62.84  E-value: 2.20e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  17 NEKPALTGVD---LHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDG----GQVILDGRDVSRLPEHRR----ATDLGRV 85
Cdd:PRK11022   15 DESAPFRAVDrisYSVKQGEVVGIVGESGSGKSVSSLAIMGLIDYPGrvmaEKLEFNGQDLQRISEKERrnlvGAEVAMI 94
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  86 FQDPMRGT----AADMQIVEnlALAARRGESRGlswgiTRDERAsyrerlaeLDL----GL---EERLTSKVGLLSGGQR 154
Cdd:PRK11022   95 FQDPMTSLnpcyTVGFQIME--AIKVHQGGNKK-----TRRQRA--------IDLlnqvGIpdpASRLDVYPHQLSGGMS 159
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2506233547 155 QALTLLMAILKKPKLLLLDEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNVI 228
Cdd:PRK11022  160 QRVMIAMAIACRPKLLIADEPTTALDVTIQAQIIELLLELQQKENMALVLITHDLALVAEAAHKIIVMYAGQVV 233
PRK15134 PRK15134
microcin C ABC transporter ATP-binding protein YejF; Provisional
17-228 2.47e-11

microcin C ABC transporter ATP-binding protein YejF; Provisional


Pssm-ID: 237917 [Multi-domain]  Cd Length: 529  Bit Score: 63.19  E-value: 2.47e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  17 NEKPALTGVDLHLEPGDFVTVIGGNGAGKST-------LLNSIAGVFAldGGQVILDGRDVSRLPEHR----RATDLGRV 85
Cdd:PRK15134   20 TVRTVVNDVSLQIEAGETLALVGESGSGKSVtalsilrLLPSPPVVYP--SGDIRFHGESLLHASEQTlrgvRGNKIAMI 97
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  86 FQDPMRGT----AADMQIVENLALaarrgeSRGLSWGITRDERASYRERLaeldlGLEE---RLTSKVGLLSGGQRQALT 158
Cdd:PRK15134   98 FQEPMVSLnplhTLEKQLYEVLSL------HRGMRREAARGEILNCLDRV-----GIRQaakRLTDYPHQLSGGERQRVM 166
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 159 LLMAILKKPKLLLLDEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNVI 228
Cdd:PRK15134  167 IAMALLTRPELLIADEPTTALDVSVQAQILQLLRELQQELNMGLLFITHNLSIVRKLADRVAVMQNGRCV 236
cbiO PRK13631
cobalt transporter ATP-binding subunit; Provisional
1-228 2.81e-11

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237451 [Multi-domain]  Cd Length: 320  Bit Score: 62.56  E-value: 2.81e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   1 MLVLKGVTKTFNKSTVNEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGV------------------FALDGGQ 62
Cdd:PRK13631   21 ILRVKNLYCVFDEKQENELVALNNISYTFEKNKIYFIIGNSGSGKSTLVTHFNGLikskygtiqvgdiyigdkKNNHELI 100
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  63 VILDGRDVSRLPEHRRAtdLGRVFQDP----MRGTAADMQIVENLALAARRGESRGLSwgitrderASYRERLAeLDLGL 138
Cdd:PRK13631  101 TNPYSKKIKNFKELRRR--VSMVFQFPeyqlFKDTIEKDIMFGPVALGVKKSEAKKLA--------KFYLNKMG-LDDSY 169
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 139 EERltSKVGlLSGGQ--RQALTLLMAIlkKPKLLLLDEHTAALDPKTASKVLALTERlVGEHGLTTLMVTHNMNDAIRLG 216
Cdd:PRK13631  170 LER--SPFG-LSGGQkrRVAIAGILAI--QPEILIFDEPTAGLDPKGEHEMMQLILD-AKANNKTVFVITHTMEHVLEVA 243
                         250
                  ....*....|..
gi 2506233547 217 NRLIMMHEGNVI 228
Cdd:PRK13631  244 DEVIVMDKGKIL 255
cbiO PRK13638
energy-coupling factor ABC transporter ATP-binding protein;
18-228 3.23e-11

energy-coupling factor ABC transporter ATP-binding protein;


Pssm-ID: 184198 [Multi-domain]  Cd Length: 271  Bit Score: 61.95  E-value: 3.23e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  18 EKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGR--DVSRLPEHRRATDLGRVFQDPmrgtaa 95
Cdd:PRK13638   13 DEPVLKGLNLDFSLSPVTGLVGANGCGKSTLFMNLSGLLRPQKGAVLWQGKplDYSKRGLLALRQQVATVFQDP------ 86
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  96 DMQIV-----ENLALAARrgesrglSWGITRDERAsyRERLAELDLGLEERLTSK-VGLLSGGQRQALTLLMAILKKPKL 169
Cdd:PRK13638   87 EQQIFytdidSDIAFSLR-------NLGVPEAEIT--RRVDEALTLVDAQHFRHQpIQCLSHGQKKRVAIAGALVLQARY 157
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2506233547 170 LLLDEHTAALDPKTASKVLALTERLVGEhGLTTLMVTHNMNDAIRLGNRLIMMHEGNVI 228
Cdd:PRK13638  158 LLLDEPTAGLDPAGRTQMIAIIRRIVAQ-GNHVIISSHDIDLIYEISDAVYVLRQGQIL 215
PRK14243 PRK14243
phosphate transporter ATP-binding protein; Provisional
21-214 3.39e-11

phosphate transporter ATP-binding protein; Provisional


Pssm-ID: 184588 [Multi-domain]  Cd Length: 264  Bit Score: 61.72  E-value: 3.39e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  21 ALTGVDLHLEPGDFVTVIGGNGAGKSTLL------NSIAGVFALDG-----GQVILDGrDVSRLPEHRRatdLGRVFQDP 89
Cdd:PRK14243   25 AVKNVWLDIPKNQITAFIGPSGCGKSTILrcfnrlNDLIPGFRVEGkvtfhGKNLYAP-DVDPVEVRRR---IGMVFQKP 100
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  90 mrgTAADMQIVENLALAARRGESRGlswgiTRDERASYRERLAELDLGLEERLTSKVGLLSGGQRQALTLLMAILKKPKL 169
Cdd:PRK14243  101 ---NPFPKSIYDNIAYGARINGYKG-----DMDELVERSLRQAALWDEVKDKLKQSGLSLSGGQQQRLCIARAIAVQPEV 172
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 2506233547 170 LLLDEHTAALDPKTASKVLALTERLVGEHglTTLMVTHNMNDAIR 214
Cdd:PRK14243  173 ILMDEPCSALDPISTLRIEELMHELKEQY--TIIIVTHNMQQAAR 215
PLN03130 PLN03130
ABC transporter C family member; Provisional
20-228 4.34e-11

ABC transporter C family member; Provisional


Pssm-ID: 215595 [Multi-domain]  Cd Length: 1622  Bit Score: 62.83  E-value: 4.34e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   20 PALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSR--LPEHRRAtdLGRVFQDPM--RGTA- 94
Cdd:PLN03130  1253 PVLHGLSFEISPSEKVGIVGRTGAGKSSMLNALFRIVELERGRILIDGCDISKfgLMDLRKV--LGIIPQAPVlfSGTVr 1330
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   95 ---------ADMQIVENLalaarrgesrglswgitrdERASYRERLAELDLGLEERLTSKVGLLSGGQRQALTLLMAILK 165
Cdd:PLN03130  1331 fnldpfnehNDADLWESL-------------------ERAHLKDVIRRNSLGLDAEVSEAGENFSVGQRQLLSLARALLR 1391
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2506233547  166 KPKLLLLDEHTAALDPKTAskvlALTERLVGEH--GLTTLMVTHNMNDAIRLgNRLIMMHEGNVI 228
Cdd:PLN03130  1392 RSKILVLDEATAAVDVRTD----ALIQKTIREEfkSCTMLIIAHRLNTIIDC-DRILVLDAGRVV 1451
cbiO PRK13648
cobalt transporter ATP-binding subunit; Provisional
21-227 6.49e-11

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184207 [Multi-domain]  Cd Length: 269  Bit Score: 60.92  E-value: 6.49e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  21 ALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVS--RLPEHRRatDLGRVFQDPmrgtaaDMQ 98
Cdd:PRK13648   24 TLKDVSFNIPKGQWTSIVGHNGSGKSTIAKLMIGIEKVKSGEIFYNNQAITddNFEKLRK--HIGIVFQNP------DNQ 95
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  99 IVENLAlaaRRGESRGL-SWGITRDErasYRERLAEL--DLGLEERLTSKVGLLSGGQRQALTLLMAILKKPKLLLLDEH 175
Cdd:PRK13648   96 FVGSIV---KYDVAFGLeNHAVPYDE---MHRRVSEAlkQVDMLERADYEPNALSGGQKQRVAIAGVLALNPSVIILDEA 169
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2506233547 176 TAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIRlGNRLIMMHEGNV 227
Cdd:PRK13648  170 TSMLDPDARQNLLDLVRKVKSEHNITIISITHDLSEAME-ADHVIVMNKGTV 220
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
4-228 9.48e-11

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 61.68  E-value: 9.48e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   4 LKGVTKTFNKSTvnekpALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRlPEHRRAT--- 80
Cdd:NF033858    4 LEGVSHRYGKTV-----ALDDVSLDIPAGCMVGLIGPDGVGKSSLLSLIAGARKIQQGRVEVLGGDMAD-ARHRRAVcpr 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  81 ------DLGR-------VFqdpmrgtaadmqivENLALAARrgesrgLsWGITRDERasyRERLAEL--DLGLEERLTSK 145
Cdd:NF033858   78 iaympqGLGKnlyptlsVF--------------ENLDFFGR------L-FGQDAAER---RRRIDELlrATGLAPFADRP 133
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 146 VGLLSGGQRQALTLLMAILKKPKLLLLDEHTAALDPKTASKVLALTERLVGEH-GLTTLMVTHNMNDAIRLgNRLIMMHE 224
Cdd:NF033858  134 AGKLSGGMKQKLGLCCALIHDPDLLILDEPTTGVDPLSRRQFWELIDRIRAERpGMSVLVATAYMEEAERF-DWLVAMDA 212

                  ....
gi 2506233547 225 GNVI 228
Cdd:NF033858  213 GRVL 216
PRK13543 PRK13543
heme ABC exporter ATP-binding protein CcmA;
17-220 1.13e-10

heme ABC exporter ATP-binding protein CcmA;


Pssm-ID: 184129 [Multi-domain]  Cd Length: 214  Bit Score: 59.86  E-value: 1.13e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  17 NEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRATDLGRvfqdpMRGTAAD 96
Cdd:PRK13543   22 NEEPVFGPLDFHVDAGEALLVQGDNGAGKTTLLRVLAGLLHVESGQIQIDGKTATRGDRSRFMAYLGH-----LPGLKAD 96
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  97 MQIVENL----ALAARRGESRGLSwgitrderasyrerlAELDLGLEERLTSKVGLLSGGQRQALTLLMAILKKPKLLLL 172
Cdd:PRK13543   97 LSTLENLhflcGLHGRRAKQMPGS---------------ALAIVGLAGYEDTLVRQLSAGQKKRLALARLWLSPAPLWLL 161
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2506233547 173 DEHTAALDPKTaskvLALTERLVGEH---GLTTLMVTHNMNDAIRLGNRLI 220
Cdd:PRK13543  162 DEPYANLDLEG----ITLVNRMISAHlrgGGAALVTTHGAYAAPPVRTRML 208
SufC COG0396
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, ...
15-208 1.22e-10

Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440165 [Multi-domain]  Cd Length: 245  Bit Score: 60.08  E-value: 1.22e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  15 TVNEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAG--VFALDGGQVILDGRDVSRLPEHRRATD-LGRVFQDPMR 91
Cdd:COG0396     9 SVEGKEILKGVNLTIKPGEVHAIMGPNGSGKSTLAKVLMGhpKYEVTSGSILLDGEDILELSPDERARAgIFLAFQYPVE 88
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  92 --GTAadmqiVENL---ALAARRGESRGLswgitRDERASYRERLAELdlGLEERLTSK---VGLlSGGQRQALTLLMAI 163
Cdd:COG0396    89 ipGVS-----VSNFlrtALNARRGEELSA-----REFLKLLKEKMKEL--GLDEDFLDRyvnEGF-SGGEKKRNEILQML 155
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 2506233547 164 LKKPKLLLLDEHTAALDPKTASKVLALTERLVGEHGlTTLMVTHN 208
Cdd:COG0396   156 LLEPKLAILDETDSGLDIDALRIVAEGVNKLRSPDR-GILIITHY 199
PRK14258 PRK14258
phosphate ABC transporter ATP-binding protein; Provisional
22-238 2.93e-10

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 184593 [Multi-domain]  Cd Length: 261  Bit Score: 59.28  E-value: 2.93e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  22 LTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDG-----------GQVILDGR-DVSRLpehRRATDLgrVFQDP 89
Cdd:PRK14258   23 LEGVSMEIYQSKVTAIIGPSGCGKSTFLKCLNRMNELESevrvegrveffNQNIYERRvNLNRL---RRQVSM--VHPKP 97
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  90 mrgTAADMQIVENLALAARRgesrgLSW--GITRDERASYRERLAELDLGLEERLTSKVGLLSGGQRQALTLLMAILKKP 167
Cdd:PRK14258   98 ---NLFPMSVYDNVAYGVKI-----VGWrpKLEIDDIVESALKDADLWDEIKHKIHKSALDLSGGQQQRLCIARALAVKP 169
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 168 KLLLLDEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIRLG----------NRLIMMHE---GNVIFDARDD 234
Cdd:PRK14258  170 KVLLMDEPCFGLDPIASMKVESLIQSLRLRSELTMVIVSHNLHQVSRLSdftaffkgneNRIGQLVEfglTKKIFNSPHD 249

                  ....
gi 2506233547 235 EKRR 238
Cdd:PRK14258  250 SRTR 253
PRK03695 PRK03695
vitamin B12-transporter ATPase; Provisional
16-235 5.59e-10

vitamin B12-transporter ATPase; Provisional


Pssm-ID: 235150 [Multi-domain]  Cd Length: 248  Bit Score: 58.02  E-value: 5.59e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  16 VNEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVfaLDG-GQVILDGRDVSRLPehrrATDLGRvfqdpMRG-- 92
Cdd:PRK03695    6 VAVSTRLGPLSAEVRAGEILHLVGPNGAGKSTLLARMAGL--LPGsGSIQFAGQPLEAWS----AAELAR-----HRAyl 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  93 -----TAADMQIVENLALAarrgesrgLSWGITRDERASYRERLAELdLGLEERLTSKVGLLSGGQ----RQALTLLM-- 161
Cdd:PRK03695   75 sqqqtPPFAMPVFQYLTLH--------QPDKTRTEAVASALNEVAEA-LGLDDKLGRSVNQLSGGEwqrvRLAAVVLQvw 145
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2506233547 162 -AILKKPKLLLLDEHTAALDPKTASKVLALTERLVgEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNVIFDARDDE 235
Cdd:PRK03695  146 pDINPAGQLLLLDEPMNSLDVAQQAALDRLLSELC-QQGIAVVMSSHDLNHTLRHADRVWLLKQGKLLASGRRDE 219
ABCC_SUR2 cd03288
ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The ...
17-228 5.70e-10

ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The sulfonylurea receptor SUR is an ATP binding cassette (ABC) protein of the ABCC/MRP family. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.


Pssm-ID: 213255 [Multi-domain]  Cd Length: 257  Bit Score: 58.38  E-value: 5.70e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  17 NEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRATDLGRVFQDPMRGTAAd 96
Cdd:cd03288    32 NLKPVLKHVKAYIKPGQKVGICGRTGSGKSSLSLAFFRMVDIFDGKIVIDGIDISKLPLHTLRSRLSIILQDPILFSGS- 110
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  97 mqIVENLALAARRGESRglSWGITrdERASYRERLAELDLGLEERLTSKVGLLSGGQRQALTLLMAILKKPKLLLLDEHT 176
Cdd:cd03288   111 --IRFNLDPECKCTDDR--LWEAL--EIAQLKNMVKSLPGGLDAVVTEGGENFSVGQRQLFCLARAFVRKSSILIMDEAT 184
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2506233547 177 AALDPKTAS---KVL--ALTERLVgehgLTTLMVTHNMNDAirlgNRLIMMHEGNVI 228
Cdd:cd03288   185 ASIDMATENilqKVVmtAFADRTV----VTIAHRVSTILDA----DLVLVLSRGILV 233
PRK10261 PRK10261
glutathione transporter ATP-binding protein; Provisional
11-228 5.97e-10

glutathione transporter ATP-binding protein; Provisional


Pssm-ID: 182342 [Multi-domain]  Cd Length: 623  Bit Score: 59.10  E-value: 5.97e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  11 FNKSTvNEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEH-----RRatDLGRV 85
Cdd:PRK10261  330 LNRVT-REVHAVEKVSFDLWPGETLSLVGESGSGKSTTGRALLRLVESQGGEIIFNGQRIDTLSPGklqalRR--DIQFI 406
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  86 FQDPM-----RGTAADmQIVENLALAarrgesrglswGITRDERAsyRERLAELdlgLEerltsKVGLL----------- 149
Cdd:PRK10261  407 FQDPYasldpRQTVGD-SIMEPLRVH-----------GLLPGKAA--AARVAWL---LE-----RVGLLpehawryphef 464
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2506233547 150 SGGQRQALTLLMAILKKPKLLLLDEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNVI 228
Cdd:PRK10261  465 SGGQRQRICIARALALNPKVIIADEAVSALDVSIRGQIINLLLDLQRDFGIAYLFISHDMAVVERISHRVAVMYLGQIV 543
dppF PRK11308
dipeptide transporter ATP-binding subunit; Provisional
21-209 6.31e-10

dipeptide transporter ATP-binding subunit; Provisional


Pssm-ID: 236898 [Multi-domain]  Cd Length: 327  Bit Score: 58.44  E-value: 6.31e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  21 ALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDV---SRLPEHRRATDLGRVFQDPM-----RG 92
Cdd:PRK11308   30 ALDGVSFTLERGKTLAVVGESGCGKSTLARLLTMIETPTGGELYYQGQDLlkaDPEAQKLLRQKIQIVFQNPYgslnpRK 109
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  93 TAADmQIVENLALAARrgesrglswgITRDERasyRERLAELdlgleerlTSKVGL-----------LSGGQRQALTLLM 161
Cdd:PRK11308  110 KVGQ-ILEEPLLINTS----------LSAAER---REKALAM--------MAKVGLrpehydryphmFSGGQRQRIAIAR 167
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 2506233547 162 AILKKPKLLLLDEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNM 209
Cdd:PRK11308  168 ALMLDPDVVVADEPVSALDVSVQAQVLNLMMDLQQELGLSYVFISHDL 215
ATM1 COG5265
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components ...
18-228 6.34e-10

ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444078 [Multi-domain]  Cd Length: 605  Bit Score: 59.06  E-value: 6.34e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  18 EKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEH--RRAtdLGRVFQDPM--RGT 93
Cdd:COG5265   370 ERPILKGVSFEVPAGKTVAIVGPSGAGKSTLARLLFRFYDVTSGRILIDGQDIRDVTQAslRAA--IGIVPQDTVlfNDT 447
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  94 aadmqIVENLALAArrgesrglsWGITRDE--RASyreRLAELD---LGLEERLTSKV---GL-LSGGQRQ----ALTLL 160
Cdd:COG5265   448 -----IAYNIAYGR---------PDASEEEveAAA---RAAQIHdfiESLPDGYDTRVgerGLkLSGGEKQrvaiARTLL 510
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2506233547 161 M--AIlkkpklLLLDEHTAALDPKTASKVLALTERLVGEHglTTLMVTHnmndaiRL-----GNRLIMMHEGNVI 228
Cdd:COG5265   511 KnpPI------LIFDEATSALDSRTERAIQAALREVARGR--TTLVIAH------RLstivdADEILVLEAGRIV 571
SapD COG4170
ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];
21-225 7.39e-10

ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];


Pssm-ID: 443330 [Multi-domain]  Cd Length: 331  Bit Score: 58.38  E-value: 7.39e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  21 ALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFAlDGGQVI-----LDGRDVSRL-PEHRRA---TDLGRVFQDPMR 91
Cdd:COG4170    22 AVDRVSLTLNEGEIRGLVGESGSGKSLIAKAICGITK-DNWHVTadrfrWNGIDLLKLsPRERRKiigREIAMIFQEPSS 100
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  92 GTAADMQIVENLALAARRGESRGLSWgitrdERASYRERLAEldlgleeRLTSKVGL-------------LSGGQRQALT 158
Cdd:COG4170   101 CLDPSAKIGDQLIEAIPSWTFKGKWW-----QRFKWRKKRAI-------ELLHRVGIkdhkdimnsypheLTEGECQKVM 168
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2506233547 159 LLMAILKKPKLLLLDEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIRLGNRLIMMHEG 225
Cdd:COG4170   169 IAMAIANQPRLLIADEPTNAMESTTQAQIFRLLARLNQLQGTSILLISHDLESISQWADTITVLYCG 235
ABCF_EF-3 cd03221
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ...
2-68 7.62e-10

ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.


Pssm-ID: 213188 [Multi-domain]  Cd Length: 144  Bit Score: 55.92  E-value: 7.62e-10
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2506233547   2 LVLKGVTKTFNKSTVnekpaLTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGR 68
Cdd:cd03221     1 IELENLSKTYGGKLL-----LKDISLTINPGDRIGLVGRNGAGKSTLLKLIAGELEPDEGIVTWGST 62
NupO COG3845
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ...
19-152 1.13e-09

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];


Pssm-ID: 443055 [Multi-domain]  Cd Length: 504  Bit Score: 58.11  E-value: 1.13e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  19 KPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRL-PEHRRATDLGRVFQDPMR-GTAAD 96
Cdd:COG3845   271 VPALKDVSLEVRAGEILGIAGVAGNGQSELAEALAGLRPPASGSIRLDGEDITGLsPRERRRLGVAYIPEDRLGrGLVPD 350
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2506233547  97 MQIVENLALAARRGE--SRG--LSWGITRdERAsyRERLAELDLgleeRLTS---KVGLLSGG 152
Cdd:COG3845   351 MSVAENLILGRYRRPpfSRGgfLDRKAIR-AFA--EELIEEFDV----RTPGpdtPARSLSGG 406
met_CoM_red_A2 TIGR03269
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ...
4-255 1.26e-09

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]


Pssm-ID: 132313 [Multi-domain]  Cd Length: 520  Bit Score: 58.28  E-value: 1.26e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   4 LKGVTKTFNkstvnEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGV--FALDGGQVILDgrdVSRLPEHRRATD 81
Cdd:TIGR03269   3 VKNLTKKFD-----GKEVLKNISFTIEEGEVLGILGRSGAGKSVLMHVLRGMdqYEPTSGRIIYH---VALCEKCGYVER 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  82 LGRVFQD-PMRGTAADMQIVE--NLALAARR-----------------GESRGLSWGITRDERASYR-----ERLAEL-- 134
Cdd:TIGR03269  75 PSKVGEPcPVCGGTLEPEEVDfwNLSDKLRRrirkriaimlqrtfalyGDDTVLDNVLEALEEIGYEgkeavGRAVDLie 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 135 DLGLEERLTSKVGLLSGGQRQALTLLMAILKKPKLLLLDEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIR 214
Cdd:TIGR03269 155 MVQLSHRITHIARDLSGGEKQRVVLARQLAKEPFLFLADEPTGTLDPQTAKLVHNALEEAVKASGISMVLTSHWPEVIED 234
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|...
gi 2506233547 215 LGNRLIMMHEGNVIFDARDDE--KRRLRVHDLLQKFEEASGGE 255
Cdd:TIGR03269 235 LSDKAIWLENGEIKEEGTPDEvvAVFMEGVSEVEKECEVEVGE 277
ABCC_NFT1 cd03369
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type ...
20-228 2.29e-09

ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type transporter 1). NFT1 belongs to the MRP (multidrug resistance-associated protein) family of ABC transporters. Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213269 [Multi-domain]  Cd Length: 207  Bit Score: 55.88  E-value: 2.29e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  20 PALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRATDLGRVFQDPmrgTAADMQI 99
Cdd:cd03369    22 PVLKNVSFKVKAGEKIGIVGRTGAGKSTLILALFRFLEAEEGKIEIDGIDISTIPLEDLRSSLTIIPQDP---TLFSGTI 98
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 100 VENLalaarrgesrglswgiTRDERASYRERLAELDLgleerltSKVGL-LSGGQRQALTLLMAILKKPKLLLLDEHTAA 178
Cdd:cd03369    99 RSNL----------------DPFDEYSDEEIYGALRV-------SEGGLnLSQGQRQLLCLARALLKRPRVLVLDEATAS 155
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2506233547 179 LDPKTAskvlALTERLVGEH--GLTTLMVTHNMNDAIRLgNRLIMMHEGNVI 228
Cdd:cd03369   156 IDYATD----ALIQKTIREEftNSTILTIAHRLRTIIDY-DKILVMDAGEVK 202
PRK13549 PRK13549
xylose transporter ATP-binding subunit; Provisional
1-211 3.47e-09

xylose transporter ATP-binding subunit; Provisional


Pssm-ID: 184134 [Multi-domain]  Cd Length: 506  Bit Score: 56.86  E-value: 3.47e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   1 MLVLKGVTKTFnkSTVnekPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALD--GGQVILDGRDVSrlPEHRR 78
Cdd:PRK13549    5 LLEMKNITKTF--GGV---KALDNVSLKVRAGEIVSLCGENGAGKSTLMKVLSGVYPHGtyEGEIIFEGEELQ--ASNIR 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  79 ATD---LGRVFQDPMrgTAADMQIVENLALAARRGESrglswGITRDERASYR--ERLAELDLGLEERLtsKVGLLSGGQ 153
Cdd:PRK13549   78 DTEragIAIIHQELA--LVKELSVLENIFLGNEITPG-----GIMDYDAMYLRaqKLLAQLKLDINPAT--PVGNLGLGQ 148
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2506233547 154 RQALTLLMAILKKPKLLLLDEHTAALDPKTASKVLALTERLvGEHGLTTLMVTHNMND 211
Cdd:PRK13549  149 QQLVEIAKALNKQARLLILDEPTASLTESETAVLLDIIRDL-KAHGIACIYISHKLNE 205
ABC_RNaseL_inhibitor_domain2 cd03237
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...
27-220 4.70e-09

The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity of more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213204 [Multi-domain]  Cd Length: 246  Bit Score: 55.49  E-value: 4.70e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  27 LHLEPGDF-----VTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRATDLGRVfqdpmrgtaadmqive 101
Cdd:cd03237    15 LEVEGGSIsesevIGILGPNGIGKTTFIKMLAGVLKPDEGDIEIELDTVSYKPQYIKADYEGTV---------------- 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 102 nlalaarrgesRGLSWGITRD--ERASYRERLAElDLGLEERLTSKVGLLSGGQRQALTLLMAILKKPKLLLLDEHTAAL 179
Cdd:cd03237    79 -----------RDLLSSITKDfyTHPYFKTEIAK-PLQIEQILDREVPELSGGELQRVAIAACLSKDADIYLLDEPSAYL 146
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 2506233547 180 DPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIRLGNRLI 220
Cdd:cd03237   147 DVEQRLMASKVIRRFAENNEKTAFVVEHDIIMIDYLADRLI 187
40850658_otr NF000106
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
4-262 5.49e-09

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;


Pssm-ID: 411078 [Multi-domain]  Cd Length: 351  Bit Score: 55.90  E-value: 5.49e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   4 LKGVTKTFNkstvnEKPALTGVDLHLEPGDFVTVIGGNGAGKSTllnsiaGVFALDggqviLDGRDVSRLP-------EH 76
Cdd:NF000106   16 VRGLVKHFG-----EVKAVDGVDLDVREGTVLGVLGP*GAA**R------GALPAH-----V*GPDAGRRPwrf*twcAN 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  77 RRATDLGRVFQDPMR-GTAADMQIVENLALAARRGE-SRglswgitRDERASYRERLAELDLglEERLTSKVGLLSGGQR 154
Cdd:NF000106   80 RRALRRTIG*HRPVR*GRRESFSGRENLYMIGR*LDlSR-------KDARARADELLERFSL--TEAAGRAAAKYSGGMR 150
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 155 QALTLLMAILKKPKLLLLDEHTAALDPKTASKVLALTERLVGEhGLTTLMVTHNMNDAIRLGNRLIMMHEGNVIFDARDD 234
Cdd:NF000106  151 RRLDLAASMIGRPAVLYLDEPTTGLDPRTRNEVWDEVRSMVRD-GATVLLTTQYMEEAEQLAHELTVIDRGRVIADGKVD 229
                         250       260
                  ....*....|....*....|....*...
gi 2506233547 235 EkRRLRVHDLLQKFEEASGGELanDRML 262
Cdd:NF000106  230 E-LKTKVGGRTLQIRPAHAAEL--DRMV 254
PRK15056 PRK15056
manganese/iron ABC transporter ATP-binding protein;
2-222 6.77e-09

manganese/iron ABC transporter ATP-binding protein;


Pssm-ID: 185016 [Multi-domain]  Cd Length: 272  Bit Score: 55.27  E-value: 6.77e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   2 LVLKGVTKTFNkstvNEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVsrlpehRRATD 81
Cdd:PRK15056    7 IVVNDVTVTWR----NGHTALRDASFTVPGGSIAALVGVNGSGKSTLFKALMGFVRLASGKISILGQPT------RQALQ 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  82 LGRVFQDPmRGTAADMQ---IVENLALAARRGESRGLSWGITRDeRASYRERLAELDLgLEERlTSKVGLLSGGQRQALT 158
Cdd:PRK15056   77 KNLVAYVP-QSEEVDWSfpvLVEDVVMMGRYGHMGWLRRAKKRD-RQIVTAALARVDM-VEFR-HRQIGELSGGQKKRVF 152
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2506233547 159 LLMAILKKPKLLLLDEHTAALDPKTASKVLALTERLVGEhGLTTLMVTHNMNDAIRLGNRLIMM 222
Cdd:PRK15056  153 LARAIAQQGQVILLDEPFTGVDVKTEARIISLLRELRDE-GKTMLVSTHNLGSVTEFCDYTVMV 215
MK0520 COG2401
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction ...
7-207 7.14e-09

ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only];


Pssm-ID: 441957 [Multi-domain]  Cd Length: 222  Bit Score: 54.58  E-value: 7.14e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   7 VTKTFNKS-TVNEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGvfALDGGQViLDGRDVSRLPEHRRATDLGRV 85
Cdd:COG2401    30 VLEAFGVElRVVERYVLRDLNLEIEPGEIVLIVGASGSGKSTLLRLLAG--ALKGTPV-AGCVDVPDNQFGREASLIDAI 106
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  86 fqdPMRGTAADmqIVENLALAarrgesrGLSwgitrdERASYRERLAEldlgleerltskvglLSGGQRQALTLLMAILK 165
Cdd:COG2401   107 ---GRKGDFKD--AVELLNAV-------GLS------DAVLWLRRFKE---------------LSTGQKFRFRLALLLAE 153
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 2506233547 166 KPKLLLLDEHTAALDPKTAsKVLALT-ERLVGEHGLTTLMVTH 207
Cdd:COG2401   154 RPKLLVIDEFCSHLDRQTA-KRVARNlQKLARRAGITLVVATH 195
PRK15134 PRK15134
microcin C ABC transporter ATP-binding protein YejF; Provisional
13-228 9.95e-09

microcin C ABC transporter ATP-binding protein YejF; Provisional


Pssm-ID: 237917 [Multi-domain]  Cd Length: 529  Bit Score: 55.48  E-value: 9.95e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  13 KSTVNEKPALTGVDLHLEPGDFVTVIGGNGAGKST----LLNSIAGvfaldGGQVILDGRDVSR------LPEHRRatdL 82
Cdd:PRK15134  293 KRTVDHNVVVKNISFTLRPGETLGLVGESGSGKSTtglaLLRLINS-----QGEIWFDGQPLHNlnrrqlLPVRHR---I 364
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  83 GRVFQDPmrgtaadmqiveNLALAARRGESRGLSWGITRDERA-SYRERLAELDLGLEErltskVGL-----------LS 150
Cdd:PRK15134  365 QVVFQDP------------NSSLNPRLNVLQIIEEGLRVHQPTlSAAQREQQVIAVMEE-----VGLdpetrhrypaeFS 427
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2506233547 151 GGQRQALTLLMAILKKPKLLLLDEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNVI 228
Cdd:PRK15134  428 GGQRQRIAIARALILKPSLIILDEPTSSLDKTVQAQILALLKSLQQKHQLAYLFISHDLHVVRALCHQVIVLRQGEVV 505
PvdE COG4615
ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion ...
2-72 1.01e-08

ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion transport and metabolism];


Pssm-ID: 443659 [Multi-domain]  Cd Length: 547  Bit Score: 55.57  E-value: 1.01e-08
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2506233547   2 LVLKGVTKTFNKSTVNEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSR 72
Cdd:COG4615   328 LELRGVTYRYPGEDGDEGFTLGPIDLTIRRGELVFIVGGNGSGKSTLAKLLTGLYRPESGEILLDGQPVTA 398
PRK11147 PRK11147
ABC transporter ATPase component; Reviewed
20-91 1.05e-08

ABC transporter ATPase component; Reviewed


Pssm-ID: 236861 [Multi-domain]  Cd Length: 635  Bit Score: 55.34  E-value: 1.05e-08
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2506233547  20 PALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDgRD--VSRLPehrratdlgrvfQDPMR 91
Cdd:PRK11147   17 PLLDNAELHIEDNERVCLVGRNGAGKSTLMKILNGEVLLDDGRIIYE-QDliVARLQ------------QDPPR 77
PRK15064 PRK15064
ABC transporter ATP-binding protein; Provisional
2-63 1.24e-08

ABC transporter ATP-binding protein; Provisional


Pssm-ID: 237894 [Multi-domain]  Cd Length: 530  Bit Score: 55.28  E-value: 1.24e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2506233547   2 LVLKGVTKTFNkstvnEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQV 63
Cdd:PRK15064  320 LEVENLTKGFD-----NGPLFKNLNLLLEAGERLAIIGENGVGKTTLLRTLVGELEPDSGTV 376
sufC PRK09580
cysteine desulfurase ATPase component; Reviewed
15-180 1.32e-08

cysteine desulfurase ATPase component; Reviewed


Pssm-ID: 181965 [Multi-domain]  Cd Length: 248  Bit Score: 54.03  E-value: 1.32e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  15 TVNEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGV--FALDGGQVILDGRDVSRL-PEHRRATDLGRVFQDPMR 91
Cdd:PRK09580   10 SVEDKAILRGLNLEVRPGEVHAIMGPNGSGKSTLSATLAGRedYEVTGGTVEFKGKDLLELsPEDRAGEGIFMAFQYPVE 89
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  92 GTAADMQIVENLALAARRgESRGLSwGITRDERASYRERLAELDLGLEERLTSKVGL-LSGGQRQALTLLMAILKKPKLL 170
Cdd:PRK09580   90 IPGVSNQFFLQTALNAVR-SYRGQE-PLDRFDFQDLMEEKIALLKMPEDLLTRSVNVgFSGGEKKRNDILQMAVLEPELC 167
                         170
                  ....*....|
gi 2506233547 171 LLDEHTAALD 180
Cdd:PRK09580  168 ILDESDSGLD 177
PRK10982 PRK10982
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
21-228 2.03e-08

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional


Pssm-ID: 182880 [Multi-domain]  Cd Length: 491  Bit Score: 54.35  E-value: 2.03e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  21 ALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSrLPEHRRATDLGRVFQDPMRGTAADMQIV 100
Cdd:PRK10982   13 ALDNVNLKVRPHSIHALMGENGAGKSTLLKCLFGIYQKDSGSILFQGKEID-FKSSKEALENGISMVHQELNLVLQRSVM 91
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 101 ENLALAarrgesRGLSWGITRDERASYRERLA---ELDLGLEERltSKVGLLSGGQRQALTLLMAILKKPKLLLLDEHTA 177
Cdd:PRK10982   92 DNMWLG------RYPTKGMFVDQDKMYRDTKAifdELDIDIDPR--AKVATLSVSQMQMIEIAKAFSYNAKIVIMDEPTS 163
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2506233547 178 ALDPKTASKVLALTERLvGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNVI 228
Cdd:PRK10982  164 SLTEKEVNHLFTIIRKL-KERGCGIVYISHKMEEIFQLCDEITILRDGQWI 213
PRK13538 PRK13538
cytochrome c biogenesis heme-transporting ATPase CcmA;
18-207 2.15e-08

cytochrome c biogenesis heme-transporting ATPase CcmA;


Pssm-ID: 184125 [Multi-domain]  Cd Length: 204  Bit Score: 52.88  E-value: 2.15e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  18 EKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPE--HRRATDLGRVfqdpmRGTAA 95
Cdd:PRK13538   13 ERILFSGLSFTLNAGELVQIEGPNGAGKTSLLRILAGLARPDAGEVLWQGEPIRRQRDeyHQDLLYLGHQ-----PGIKT 87
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  96 DMQIVENLALAARrgesrgLSWGITRDERASYRERlaeldLGLEERLTSKVGLLSGGQR------------QALTLLmai 163
Cdd:PRK13538   88 ELTALENLRFYQR------LHGPGDDEALWEALAQ-----VGLAGFEDVPVRQLSAGQQrrvalarlwltrAPLWIL--- 153
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 2506233547 164 lkkpkllllDEHTAALDpKTASKVLaltERLVGEH---GLTTLMVTH 207
Cdd:PRK13538  154 ---------DEPFTAID-KQGVARL---EALLAQHaeqGGMVILTTH 187
ABCG_White cd03234
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ...
17-229 2.20e-08

White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.


Pssm-ID: 213201 [Multi-domain]  Cd Length: 226  Bit Score: 53.04  E-value: 2.20e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  17 NEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDG---GQVILDGRDVSRlpeHRRATDLGRVFQDPMrgT 93
Cdd:cd03234    18 KYARILNDVSLHVESGQVMAILGSSGSGKTTLLDAISGRVEGGGttsGQILFNGQPRKP---DQFQKCVAYVRQDDI--L 92
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  94 AADMQIVENLALAARRGESRGLSWGItRDERAsyrERLAELDLGLEERLTSKVGLLSGGQRQALTLLMAILKKPKLLLLD 173
Cdd:cd03234    93 LPGLTVRETLTYTAILRLPRKSSDAI-RKKRV---EDVLLRDLALTRIGGNLVKGISGGERRRVSIAVQLLWDPKVLILD 168
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2506233547 174 EHTAALDPKTASKVLALTERLvGEHGLTTLMVTHN-MNDAIRLGNRLIMMHEGNVIF 229
Cdd:cd03234   169 EPTSGLDSFTALNLVSTLSQL-ARRNRIVILTIHQpRSDLFRLFDRILLLSSGEIVY 224
hmuV PRK13547
heme ABC transporter ATP-binding protein;
22-230 2.21e-08

heme ABC transporter ATP-binding protein;


Pssm-ID: 184132 [Multi-domain]  Cd Length: 272  Bit Score: 53.68  E-value: 2.21e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  22 LTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDG--------GQVILDGRDVSRLPEHRRATDLGRVFQDPMRGT 93
Cdd:PRK13547   17 LRDLSLRIEPGRVTALLGRNGAGKSTLLKALAGDLTGGGaprgarvtGDVTLNGEPLAAIDAPRLARLRAVLPQAAQPAF 96
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  94 A--ADMQIVENLALAARRG-----ESRGLSWgitrdeRASYRERLAELDlgleerlTSKVGLLSGGQ------RQALTLL 160
Cdd:PRK13547   97 AfsAREIVLLGRYPHARRAgalthRDGEIAW------QALALAGATALV-------GRDVTTLSGGElarvqfARVLAQL 163
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2506233547 161 M---AILKKPKLLLLDEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNVIFD 230
Cdd:PRK13547  164 WpphDAAQPPRYLLLDEPTAALDLAHQHRLLDTVRRLARDWNLGVLAIVHDPNLAARHADRIAMLADGAIVAH 236
ABC_CcmA_heme_exporter cd03231
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ...
18-207 2.36e-08

Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.


Pssm-ID: 213198 [Multi-domain]  Cd Length: 201  Bit Score: 52.88  E-value: 2.36e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  18 EKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRATDLGRVFQDPMRGTaadM 97
Cdd:cd03231    12 GRALFSGLSFTLAAGEALQVTGPNGSGKTTLLRILAGLSPPLAGRVLLNGGPLDFQRDSIARGLLYLGHAPGIKTT---L 88
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  98 QIVENLALAARRGesrglswgitrdERASYRERLAELDL-GLEERLtskVGLLSGGQRQALTLLMAILKKPKLLLLDEHT 176
Cdd:cd03231    89 SVLENLRFWHADH------------SDEQVEEALARVGLnGFEDRP---VAQLSAGQQRRVALARLLLSGRPLWILDEPT 153
                         170       180       190
                  ....*....|....*....|....*....|...
gi 2506233547 177 AALDpktASKVLALTERLVG--EHGLTTLMVTH 207
Cdd:cd03231   154 TALD---KAGVARFAEAMAGhcARGGMVVLTTH 183
rim_protein TIGR01257
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...
1-225 3.36e-08

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]


Pssm-ID: 130324 [Multi-domain]  Cd Length: 2272  Bit Score: 54.25  E-value: 3.36e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547    1 MLVLKGVTKTFNKSTvneKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVsrlpehrrAT 80
Cdd:TIGR01257 1937 ILRLNELTKVYSGTS---SPAVDRLCVGVRPGECFGLLGVNGAGKTTTFKMLTGDTTVTSGDATVAGKSI--------LT 2005
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   81 DLGRVFQD----PMRGTAADMQI-VENLALAAR-RGE-----SRGLSWGITRDERASYRERLAeldlgleerltskvGLL 149
Cdd:TIGR01257 2006 NISDVHQNmgycPQFDAIDDLLTgREHLYLYARlRGVpaeeiEKVANWSIQSLGLSLYADRLA--------------GTY 2071
                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2506233547  150 SGGQRQALTLLMAILKKPKLLLLDEHTAALDPKtASKVLALTERLVGEHGLTTLMVTHNMNDAIRLGNRLIMMHEG 225
Cdd:TIGR01257 2072 SGGNKRKLSTAIALIGCPPLVLLDEPTTGMDPQ-ARRMLWNTIVSIIREGRAVVLTSHSMEECEALCTRLAIMVKG 2146
MglA COG1129
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
19-233 4.49e-08

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440745 [Multi-domain]  Cd Length: 497  Bit Score: 53.48  E-value: 4.49e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  19 KPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSR-------------LPEHRRATdlgrv 85
Cdd:COG1129   265 GGVVRDVSFSVRAGEILGIAGLVGAGRTELARALFGADPADSGEIRLDGKPVRIrsprdairagiayVPEDRKGE----- 339
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  86 fqdpmrGTAADMQIVENLALAARRGESRglsWGI--TRDERASYRERLAELDL---GLEErltsKVGLLSGGQRQ----- 155
Cdd:COG1129   340 ------GLVLDLSIRENITLASLDRLSR---GGLldRRRERALAEEYIKRLRIktpSPEQ----PVGNLSGGNQQkvvla 406
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 156 -ALT-----LLMailkkpkllllDEHTAALDPKTASKVLALTERLVGEhGLTTLMVTHNMNDAIRLGNRLIMMHEGNV-- 227
Cdd:COG1129   407 kWLAtdpkvLIL-----------DEPTRGIDVGAKAEIYRLIRELAAE-GKAVIVISSELPELLGLSDRILVMREGRIvg 474

                  ....*.
gi 2506233547 228 IFDARD 233
Cdd:COG1129   475 ELDREE 480
PRK10762 PRK10762
D-ribose transporter ATP binding protein; Provisional
1-185 5.46e-08

D-ribose transporter ATP binding protein; Provisional


Pssm-ID: 236755 [Multi-domain]  Cd Length: 501  Bit Score: 53.08  E-value: 5.46e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   1 MLVLKGVTKTFnkstvnekP---ALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVS-RLPEH 76
Cdd:PRK10762    4 LLQLKGIDKAF--------PgvkALSGAALNVYPGRVMALVGENGAGKSTMMKVLTGIYTRDAGSILYLGKEVTfNGPKS 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  77 RRATDLGRVFQDpmRGTAADMQIVENLALaarrGESRGLSWGitrdeRASYRERLAELD-----LGLEERLTSKVGLLSG 151
Cdd:PRK10762   76 SQEAGIGIIHQE--LNLIPQLTIAENIFL----GREFVNRFG-----RIDWKKMYAEADkllarLNLRFSSDKLVGELSI 144
                         170       180       190
                  ....*....|....*....|....*....|....*
gi 2506233547 152 GQRQALTLLMAILKKPKLLLLDEHTAAL-DPKTAS 185
Cdd:PRK10762  145 GEQQMVEIAKVLSFESKVIIMDEPTDALtDTETES 179
GguA NF040905
sugar ABC transporter ATP-binding protein;
1-235 8.32e-08

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 52.48  E-value: 8.32e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   1 MLVLKGVTKTFnkstvnekP---ALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFAlDG---GQVILDGrDVSRLP 74
Cdd:NF040905    1 ILEMRGITKTF--------PgvkALDDVNLSVREGEIHALCGENGAGKSTLMKVLSGVYP-HGsyeGEILFDG-EVCRFK 70
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  75 EHRRATDLGRVF--QD----PMrgtaadMQIVENLALAARRGeSRGL-SWGITRdERAsyRERLAELdlGLEERLTSKVG 147
Cdd:NF040905   71 DIRDSEALGIVIihQElaliPY------LSIAENIFLGNERA-KRGViDWNETN-RRA--RELLAKV--GLDESPDTLVT 138
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 148 LLSGGQRQALTLLMAILKKPKLLLLDEHTAALDPKTASKVLALTERLvGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNV 227
Cdd:NF040905  139 DIGVGKQQLVEIAKALSKDVKLLILDEPTAALNEEDSAALLDLLLEL-KAQGITSIIISHKLNEIRRVADSITVLRDGRT 217
                         250
                  ....*....|
gi 2506233547 228 I--FDARDDE 235
Cdd:NF040905  218 IetLDCRADE 227
PLN03211 PLN03211
ABC transporter G-25; Provisional
15-232 8.41e-08

ABC transporter G-25; Provisional


Pssm-ID: 215634 [Multi-domain]  Cd Length: 659  Bit Score: 52.57  E-value: 8.41e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  15 TVNEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDG--GQVILDGRDVSRlPEHRRAtdlGRVFQDPMrg 92
Cdd:PLN03211   77 QIQERTILNGVTGMASPGEILAVLGPSGSGKSTLLNALAGRIQGNNftGTILANNRKPTK-QILKRT---GFVTQDDI-- 150
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  93 TAADMQIVENLALAARRGESRGLswgiTRDERASYRERLAElDLGLEERLTSKVGL-----LSGGQRQALTLLMAILKKP 167
Cdd:PLN03211  151 LYPHLTVRETLVFCSLLRLPKSL----TKQEKILVAESVIS-ELGLTKCENTIIGNsfirgISGGERKRVSIAHEMLINP 225
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2506233547 168 KLLLLDEHTAALDpKTASKVLALTERLVGEHGLTTLMVTHNMNDAI-RLGNRLIMMHEGNVIFDAR 232
Cdd:PLN03211  226 SLLILDEPTSGLD-ATAAYRLVLTLGSLAQKGKTIVTSMHQPSSRVyQMFDSVLVLSEGRCLFFGK 290
ycf16 CHL00131
sulfate ABC transporter protein; Validated
13-89 8.89e-08

sulfate ABC transporter protein; Validated


Pssm-ID: 214372 [Multi-domain]  Cd Length: 252  Bit Score: 51.57  E-value: 8.89e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  13 KSTVNEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAG--VFALDGGQVILDGRDVSRL-PEHRRATDLGRVFQDP 89
Cdd:CHL00131   14 HASVNENEILKGLNLSINKGEIHAIMGPNGSGKSTLSKVIAGhpAYKILEGDILFKGESILDLePEERAHLGIFLAFQYP 93
PRK09700 PRK09700
D-allose ABC transporter ATP-binding protein AlsA;
4-234 1.16e-07

D-allose ABC transporter ATP-binding protein AlsA;


Pssm-ID: 182036 [Multi-domain]  Cd Length: 510  Bit Score: 52.09  E-value: 1.16e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   4 LKGVTKTFNKSTVNEKPALTGVD--------LHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVS-RLP 74
Cdd:PRK09700  253 MKENVSNLAHETVFEVRNVTSRDrkkvrdisFSVCRGEILGFAGLVGSGRTELMNCLFGVDKRAGGEIRLNGKDISpRSP 332
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  75 ------------EHRRATdlgrvfqdpmrGTAADMQIVENLALAARRGESR-GLSWGI--TRDERASYRERLAELDL--- 136
Cdd:PRK09700  333 ldavkkgmayitESRRDN-----------GFFPNFSIAQNMAISRSLKDGGyKGAMGLfhEVDEQRTAENQRELLALkch 401
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 137 GLEERLTSkvglLSGGQRQALTLLMAILKKPKLLLLDEHTAALDPKTASKVLALTERLvGEHGLTTLMVTHNMNDAIRLG 216
Cdd:PRK09700  402 SVNQNITE----LSGGNQQKVLISKWLCCCPEVIIFDEPTRGIDVGAKAEIYKVMRQL-ADDGKVILMVSSELPEIITVC 476
                         250       260
                  ....*....|....*....|
gi 2506233547 217 NRLIMMHEGNV--IFDARDD 234
Cdd:PRK09700  477 DRIAVFCEGRLtqILTNRDD 496
PRK10522 PRK10522
multidrug transporter membrane component/ATP-binding component; Provisional
2-249 1.68e-07

multidrug transporter membrane component/ATP-binding component; Provisional


Pssm-ID: 236707 [Multi-domain]  Cd Length: 547  Bit Score: 51.90  E-value: 1.68e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   2 LVLKGVTKTFNKSTVNEKPaltgVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVS-RLPEHRRA- 79
Cdd:PRK10522  323 LELRNVTFAYQDNGFSVGP----INLTIKRGELLFLIGGNGSGKSTLAMLLTGLYQPQSGEILLDGKPVTaEQPEDYRKl 398
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  80 -----TDLgRVFQDPM--RGTAADMQIVEnlalaarrgesrglswgitrderaSYRERlaeldLGLEERLTSKVGL---- 148
Cdd:PRK10522  399 fsavfTDF-HLFDQLLgpEGKPANPALVE------------------------KWLER-----LKMAHKLELEDGRisnl 448
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 149 -LSGGQRQALTLLMAILKKPKLLLLDEHTAALDP---KTASKVLAlteRLVGEHGLTTLMVTHnmNDA-IRLGNRLIMMH 223
Cdd:PRK10522  449 kLSKGQKKRLALLLALAEERDILLLDEWAADQDPhfrREFYQVLL---PLLQEMGKTIFAISH--DDHyFIHADRLLEMR 523
                         250       260
                  ....*....|....*....|....*.
gi 2506233547 224 EGNVIfdARDDEKRRLRVHDLLQKFE 249
Cdd:PRK10522  524 NGQLS--ELTGEERDAASRDAVARTA 547
PRK10789 PRK10789
SmdA family multidrug ABC transporter permease/ATP-binding protein;
17-228 3.65e-07

SmdA family multidrug ABC transporter permease/ATP-binding protein;


Pssm-ID: 182732 [Multi-domain]  Cd Length: 569  Bit Score: 50.87  E-value: 3.65e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  17 NEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRATDLGRVFQDPMRGTAAd 96
Cdd:PRK10789  326 TDHPALENVNFTLKPGQMLGICGPTGSGKSTLLSLIQRHFDVSEGDIRFHDIPLTKLQLDSWRSRLAVVSQTPFLFSDT- 404
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  97 mqIVENLALaarrGESRGLSWGITRDER-ASYRERLAELDLGLEERLTSKVGLLSGGQRQALTLLMAILKKPKLLLLDEH 175
Cdd:PRK10789  405 --VANNIAL----GRPDATQQEIEHVARlASVHDDILRLPQGYDTEVGERGVMLSGGQKQRISIARALLLNAEILILDDA 478
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2506233547 176 TAALDPKTASKVLAlTERLVGEHglTTLMVTHNMNDAIRLGNRLIMMHEGNVI 228
Cdd:PRK10789  479 LSAVDGRTEHQILH-NLRQWGEG--RTVIISAHRLSALTEASEILVMQHGHIA 528
MRP_assoc_pro TIGR00957
multi drug resistance-associated protein (MRP); This model describes multi drug ...
22-227 6.15e-07

multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]


Pssm-ID: 188098 [Multi-domain]  Cd Length: 1522  Bit Score: 50.33  E-value: 6.15e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   22 LTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRATDLGRVFQDPMRGTAAdmqIVE 101
Cdd:TIGR00957 1302 LRHINVTIHGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGLNIAKIGLHDLRFKITIIPQDPVLFSGS---LRM 1378
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  102 NLALAARRGESRgLSWGItrdERASYRERLAELDLGLEERLTSKVGLLSGGQRQALTLLMAILKKPKLLLLDEHTAALDP 181
Cdd:TIGR00957 1379 NLDPFSQYSDEE-VWWAL---ELAHLKTFVSALPDKLDHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDL 1454
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*.
gi 2506233547  182 KTASKVLAlTERLVGEHgLTTLMVTHNMNdAIRLGNRLIMMHEGNV 227
Cdd:TIGR00957 1455 ETDNLIQS-TIRTQFED-CTVLTIAHRLN-TIMDYTRVIVLDKGEV 1497
PRK10762 PRK10762
D-ribose transporter ATP binding protein; Provisional
20-239 6.46e-07

D-ribose transporter ATP binding protein; Provisional


Pssm-ID: 236755 [Multi-domain]  Cd Length: 501  Bit Score: 50.00  E-value: 6.46e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  20 PALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVS-RLPEHRRATDLGRVFQDPMR-GTAADM 97
Cdd:PRK10762  266 PGVNDVSFTLRKGEILGVSGLMGAGRTELMKVLYGALPRTSGYVTLDGHEVVtRSPQDGLANGIVYISEDRKRdGLVLGM 345
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  98 QIVENLALAARRGESRGlsWGITRDERasyrERLAELDL---------GLEERltskVGLLSGGQRQALTLLMAILKKPK 168
Cdd:PRK10762  346 SVKENMSLTALRYFSRA--GGSLKHAD----EQQAVSDFirlfniktpSMEQA----IGLLSGGNQQKVAIARGLMTRPK 415
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2506233547 169 LLLLDEHTAALDPKTASKVLALTERLVGEhGLTTLMVTHNMNDAIRLGNRLIMMHEGNVI--FDARDDEKRRL 239
Cdd:PRK10762  416 VLILDEPTRGVDVGAKKEIYQLINQFKAE-GLSIILVSSEMPEVLGMSDRILVMHEGRISgeFTREQATQEKL 487
PRK13540 PRK13540
cytochrome c biogenesis protein CcmA; Provisional
17-207 1.24e-06

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 184127 [Multi-domain]  Cd Length: 200  Bit Score: 48.02  E-value: 1.24e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  17 NEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRlpehRRATdlgrvFQdpmrgtaad 96
Cdd:PRK13540   12 HDQPLLQQISFHLPAGGLLHLKGSNGAGKTTLLKLIAGLLNPEKGEILFERQSIKK----DLCT-----YQ--------- 73
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  97 mqivENLALAarrGESRGLSWGITRDERASYRERLAELDLGLEERLT---------SKVGLLSGGQRQALTLLMAILKKP 167
Cdd:PRK13540   74 ----KQLCFV---GHRSGINPYLTLRENCLYDIHFSPGAVGITELCRlfslehlidYPCGLLSSGQKRQVALLRLWMSKA 146
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 2506233547 168 KLLLLDEHTAALDPKTASKVLALTErlvgEH---GLTTLMVTH 207
Cdd:PRK13540  147 KLWLLDEPLVALDELSLLTIITKIQ----EHrakGGAVLLTSH 185
PRK15093 PRK15093
peptide ABC transporter ATP-binding protein SapD;
21-235 3.23e-06

peptide ABC transporter ATP-binding protein SapD;


Pssm-ID: 185049 [Multi-domain]  Cd Length: 330  Bit Score: 47.49  E-value: 3.23e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  21 ALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGV----FALDGGQVILDGRDVSRL-PEHRR---ATDLGRVFQDPMRG 92
Cdd:PRK15093   22 AVDRVSMTLTEGEIRGLVGESGSGKSLIAKAICGVtkdnWRVTADRMRFDDIDLLRLsPRERRklvGHNVSMIFQEPQSC 101
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  93 TAADMQIVENLALAARRGESRGLSWgitrdERASYRERLAeldlgLEerLTSKVGL-------------LSGGQRQALTL 159
Cdd:PRK15093  102 LDPSERVGRQLMQNIPGWTYKGRWW-----QRFGWRKRRA-----IE--LLHRVGIkdhkdamrsfpyeLTEGECQKVMI 169
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2506233547 160 LMAILKKPKLLLLDEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNVIFDARDDE 235
Cdd:PRK15093  170 AIALANQPRLLIADEPTNAMEPTTQAQIFRLLTRLNQNNNTTILLISHDLQMLSQWADKINVLYCGQTVETAPSKE 245
PTZ00243 PTZ00243
ABC transporter; Provisional
22-181 4.56e-06

ABC transporter; Provisional


Pssm-ID: 240327 [Multi-domain]  Cd Length: 1560  Bit Score: 47.47  E-value: 4.56e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   22 LTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSR--LPEHRRATDLgrVFQDPM--RGTAAdm 97
Cdd:PTZ00243  1326 LRGVSFRIAPREKVGIVGRTGSGKSTLLLTFMRMVEVCGGEIRVNGREIGAygLRELRRQFSM--IPQDPVlfDGTVR-- 1401
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   98 QIVENLALAARRGESRGLswgitrdERASYRERLAELDLGLEERLTSKVGLLSGGQRQALTLLMAILKKPKL-LLLDEHT 176
Cdd:PTZ00243  1402 QNVDPFLEASSAEVWAAL-------ELVGLRERVASESEGIDSRVLEGGSNYSVGQRQLMCMARALLKKGSGfILMDEAT 1474

                   ....*
gi 2506233547  177 AALDP 181
Cdd:PTZ00243  1475 ANIDP 1479
MRP_assoc_pro TIGR00957
multi drug resistance-associated protein (MRP); This model describes multi drug ...
17-210 6.03e-06

multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]


Pssm-ID: 188098 [Multi-domain]  Cd Length: 1522  Bit Score: 47.25  E-value: 6.03e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   17 NEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGrDVSRLPEH--------RRATDLGRVFQD 88
Cdd:TIGR00957  649 DLPPTLNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVHMKG-SVAYVPQQawiqndslRENILFGKALNE 727
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   89 PMRgtaadMQIVENLALaarrgesrglswgitrderasyrerLAELDL---GLEERLTSKVGLLSGGQRQALTLLMAILK 165
Cdd:TIGR00957  728 KYY-----QQVLEACAL-------------------------LPDLEIlpsGDRTEIGEKGVNLSGGQKQRVSLARAVYS 777
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*....
gi 2506233547  166 KPKLLLLDEHTAALDPKTASKVLaltERLVGEHGL----TTLMVTHNMN 210
Cdd:TIGR00957  778 NADIYLFDDPLSAVDAHVGKHIF---EHVIGPEGVlknkTRILVTHGIS 823
PLN03232 PLN03232
ABC transporter C family member; Provisional
11-225 8.52e-06

ABC transporter C family member; Provisional


Pssm-ID: 215640 [Multi-domain]  Cd Length: 1495  Bit Score: 46.89  E-value: 8.52e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   11 FNKSTVNEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFA-LDGGQVILDGrDVSRLPEhrratdLGRVFQDP 89
Cdd:PLN03232   622 FSWDSKTSKPTLSDINLEIPVGSLVAIVGGTGEGKTSLISAMLGELShAETSSVVIRG-SVAYVPQ------VSWIFNAT 694
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   90 MRgtaadmqivENLALAARRGESRglsWGITRDERASYRerlaELDLgLEERLTSKVGL----LSGGQRQALTLLMAILK 165
Cdd:PLN03232   695 VR---------ENILFGSDFESER---YWRAIDVTALQH----DLDL-LPGRDLTEIGErgvnISGGQKQRVSMARAVYS 757
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2506233547  166 KPKLLLLDEHTAALDPKTASKVL--ALTERLVGEhglTTLMVTHNMNdAIRLGNRLIMMHEG 225
Cdd:PLN03232   758 NSDIYIFDDPLSALDAHVAHQVFdsCMKDELKGK---TRVLVTNQLH-FLPLMDRIILVSEG 815
CFTR_protein TIGR01271
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ...
20-229 8.52e-06

cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]


Pssm-ID: 273530 [Multi-domain]  Cd Length: 1490  Bit Score: 46.83  E-value: 8.52e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   20 PALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRdVSRLPEhrratdlgrvFQDPMRGTaadmqI 99
Cdd:TIGR01271  440 PVLKNISFKLEKGQLLAVAGSTGSGKSSLLMMIMGELEPSEGKIKHSGR-ISFSPQ----------TSWIMPGT-----I 503
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  100 VENLAlaarrgesrglsWGITRDErasYRERLAELDLGLEERLT-----SKVGL------LSGGQRQALTLLMAILKKPK 168
Cdd:TIGR01271  504 KDNII------------FGLSYDE---YRYTSVIKACQLEEDIAlfpekDKTVLgeggitLSGGQRARISLARAVYKDAD 568
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2506233547  169 LLLLDEHTAALDpktaskvlALTERLVGEHGLTTLM-------VTHNMnDAIRLGNRLIMMHEGNVIF 229
Cdd:TIGR01271  569 LYLLDSPFTHLD--------VVTEKEIFESCLCKLMsnktrilVTSKL-EHLKKADKILLLHEGVCYF 627
met_CoM_red_A2 TIGR03269
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ...
21-228 1.29e-05

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]


Pssm-ID: 132313 [Multi-domain]  Cd Length: 520  Bit Score: 45.95  E-value: 1.29e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  21 ALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQV-ILDGRD----VSRLPEHR-RATD-LGRVFQD----P 89
Cdd:TIGR03269 299 AVDNVSLEVKEGEIFGIVGTSGAGKTTLSKIIAGVLEPTSGEVnVRVGDEwvdmTKPGPDGRgRAKRyIGILHQEydlyP 378
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  90 MRgtaadmQIVENLAlaarrgESRGLSWgitRDERASYRERLAELDLGLEERLTSKV-----GLLSGGQRQALTLLMAIL 164
Cdd:TIGR03269 379 HR------TVLDNLT------EAIGLEL---PDELARMKAVITLKMVGFDEEKAEEIldkypDELSEGERHRVALAQVLI 443
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2506233547 165 KKPKLLLLDEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNVI 228
Cdd:TIGR03269 444 KEPRIVILDEPTGTMDPITKVDVTHSILKAREEMEQTFIIVSHDMDFVLDVCDRAALMRDGKIV 507
ABC_ABC_ChvD TIGR03719
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ...
5-65 1.35e-05

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.


Pssm-ID: 274744 [Multi-domain]  Cd Length: 552  Bit Score: 46.08  E-value: 1.35e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2506233547   5 KGVTKTFNkstvnEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVIL 65
Cdd:TIGR03719 326 ENLTKAFG-----DKLLIDDLSFKLPPGGIVGVIGPNGAGKSTLFRMITGQEQPDSGTIEI 381
PRK13409 PRK13409
ribosome biogenesis/translation initiation ATPase RLI;
27-220 1.95e-05

ribosome biogenesis/translation initiation ATPase RLI;


Pssm-ID: 184037 [Multi-domain]  Cd Length: 590  Bit Score: 45.57  E-value: 1.95e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  27 LHLEPGDF-----VTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRdVSRLPEHRRAtdlgrvfqdpmrgtAADMQIVE 101
Cdd:PRK13409  355 LEVEGGEIyegevIGIVGPNGIGKTTFAKLLAGVLKPDEGEVDPELK-ISYKPQYIKP--------------DYDGTVED 419
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 102 NLALAARRGESrglSWgitrderasYRERLAElDLGLEERLTSKVGLLSGGQRQALTLLMAILKKPKLLLLDEHTAALDP 181
Cdd:PRK13409  420 LLRSITDDLGS---SY---------YKSEIIK-PLQLERLLDKNVKDLSGGELQRVAIAACLSRDADLYLLDEPSAHLDV 486
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 2506233547 182 K---TASKVLaltERLVGEHGLTTLMVTHN--MNDAIrlGNRLI 220
Cdd:PRK13409  487 EqrlAVAKAI---RRIAEEREATALVVDHDiyMIDYI--SDRLM 525
xylG TIGR02633
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ...
25-227 2.19e-05

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 131681 [Multi-domain]  Cd Length: 500  Bit Score: 45.20  E-value: 2.19e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  25 VDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVF-ALDGGQVILDGRDVS-RLPEHRRATDLGRVFQDPMR-GTAADMQIVE 101
Cdd:TIGR02633 279 VSFSLRRGEILGVAGLVGAGRTELVQALFGAYpGKFEGNVFINGKPVDiRNPAQAIRAGIAMVPEDRKRhGIVPILGVGK 358
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 102 NLALAARRGESrglswGITRDERAsyrerlAELDLGLEE--RLTSK-------VGLLSGGQRQALTLLMAILKKPKLLLL 172
Cdd:TIGR02633 359 NITLSVLKSFC-----FKMRIDAA------AELQIIGSAiqRLKVKtaspflpIGRLSGGNQQKAVLAKMLLTNPRVLIL 427
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2506233547 173 DEHTAALDPKTASKVLALTERLVGEhGLTTLMVTHNMNDAIRLGNRLIMMHEGNV 227
Cdd:TIGR02633 428 DEPTRGVDVGAKYEIYKLINQLAQE-GVAIIVVSSELAEVLGLSDRVLVIGEGKL 481
3a01205 TIGR00956
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
22-207 2.61e-05

Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273362 [Multi-domain]  Cd Length: 1394  Bit Score: 45.48  E-value: 2.61e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   22 LTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGvfALDGGqVILDGRDVSRLPEhrRATDLGRVF-----QDPMRGTAAd 96
Cdd:TIGR00956  779 LNNVDGWVKPGTLTALMGASGAGKTTLLNVLAE--RVTTG-VITGGDRLVNGRP--LDSSFQRSIgyvqqQDLHLPTST- 852
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   97 mqIVENLALAA--RRGESrglswgITRDERASYRERLAELdLGLEERLTSKVGL----LSGGQRQALTL---LMAilKKP 167
Cdd:TIGR00956  853 --VRESLRFSAylRQPKS------VSKSEKMEYVEEVIKL-LEMESYADAVVGVpgegLNVEQRKRLTIgveLVA--KPK 921
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|
gi 2506233547  168 KLLLLDEHTAALDPKTASKVLALTERLVgEHGLTTLMVTH 207
Cdd:TIGR00956  922 LLLFLDEPTSGLDSQTAWSICKLMRKLA-DHGQAILCTIH 960
PRK11831 PRK11831
phospholipid ABC transporter ATP-binding protein MlaF;
18-240 3.37e-05

phospholipid ABC transporter ATP-binding protein MlaF;


Pssm-ID: 236997 [Multi-domain]  Cd Length: 269  Bit Score: 43.99  E-value: 3.37e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  18 EKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDV-----SRLPEHRRATDLgrVFQDPMRG 92
Cdd:PRK11831   19 NRCIFDNISLTVPRGKITAIMGPSGIGKTTLLRLIGGQIAPDHGEILFDGENIpamsrSRLYTVRKRMSM--LFQSGALF 96
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  93 TaaDMQIVENLALAARrgESRGLSWGITrdeRASYRERLAELDL-GLEERLTSKvglLSGGQRQALTLLMAILKKPKLLL 171
Cdd:PRK11831   97 T--DMNVFDNVAYPLR--EHTQLPAPLL---HSTVMMKLEAVGLrGAAKLMPSE---LSGGMARRAALARAIALEPDLIM 166
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2506233547 172 LDEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNVIFDA-----RDDEKRRLR 240
Cdd:PRK11831  167 FDEPFVGQDPITMGVLVKLISELNSALGVTCVVVSHDVPEVLSIADHAYIVADKKIVAHGsaqalQANPDPRVR 240
PLN03130 PLN03130
ABC transporter C family member; Provisional
10-227 3.37e-05

ABC transporter C family member; Provisional


Pssm-ID: 215595 [Multi-domain]  Cd Length: 1622  Bit Score: 45.11  E-value: 3.37e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   10 TFNKSTVNEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVF-ALDGGQVILDGRdVSRLPEhrratdLGRVFQD 88
Cdd:PLN03130   621 YFSWDSKAERPTLSNINLDVPVGSLVAIVGSTGEGKTSLISAMLGELpPRSDASVVIRGT-VAYVPQ------VSWIFNA 693
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   89 PMRgtaadmqivENLALaarrgesrGLSWGITRDERASYRERLA-ELDLgLEERLTSKVGL----LSGGQRQALTLLMAI 163
Cdd:PLN03130   694 TVR---------DNILF--------GSPFDPERYERAIDVTALQhDLDL-LPGGDLTEIGErgvnISGGQKQRVSMARAV 755
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2506233547  164 LKKPKLLLLDEHTAALDPKTASKVL--ALTERLVGEhglTTLMVTHNMNDAIRLgNRLIMMHEGNV 227
Cdd:PLN03130   756 YSNSDVYIFDDPLSALDAHVGRQVFdkCIKDELRGK---TRVLVTNQLHFLSQV-DRIILVHEGMI 817
PRK11819 PRK11819
putative ABC transporter ATP-binding protein; Reviewed
5-65 4.08e-05

putative ABC transporter ATP-binding protein; Reviewed


Pssm-ID: 236992 [Multi-domain]  Cd Length: 556  Bit Score: 44.34  E-value: 4.08e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2506233547   5 KGVTKTFNkstvnEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVIL 65
Cdd:PRK11819  328 ENLSKSFG-----DRLLIDDLSFSLPPGGIVGIIGPNGAGKSTLFKMITGQEQPDSGTIKI 383
znuC PRK09544
high-affinity zinc transporter ATPase; Reviewed
1-63 6.61e-05

high-affinity zinc transporter ATPase; Reviewed


Pssm-ID: 181939 [Multi-domain]  Cd Length: 251  Bit Score: 43.18  E-value: 6.61e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2506233547   1 MLVLKGVTKTFNKSTVnekpaLTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQV 63
Cdd:PRK09544    4 LVSLENVSVSFGQRRV-----LSDVSLELKPGKILTLLGPNGAGKSTLVRVVLGLVAPDEGVI 61
YddA COG4178
ABC-type uncharacterized transport system, permease and ATPase components [General function ...
17-54 1.52e-04

ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only];


Pssm-ID: 443337 [Multi-domain]  Cd Length: 571  Bit Score: 42.87  E-value: 1.52e-04
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 2506233547  17 NEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAG 54
Cdd:COG4178   374 DGRPLLEDLSLSLKPGERLLITGPSGSGKSTLLRAIAG 411
tagH PRK13545
teichoic acids export protein ATP-binding subunit; Provisional
21-67 1.95e-04

teichoic acids export protein ATP-binding subunit; Provisional


Pssm-ID: 184130 [Multi-domain]  Cd Length: 549  Bit Score: 42.18  E-value: 1.95e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 2506233547  21 ALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDG 67
Cdd:PRK13545   39 ALNNISFEVPEGEIVGIIGLNGSGKSTLSNLIAGVTMPNKGTVDIKG 85
ABCC_CFTR1 cd03291
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The ...
20-229 1.96e-04

ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The CFTR subfamily domain 1. The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits, or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.


Pssm-ID: 213258 [Multi-domain]  Cd Length: 282  Bit Score: 41.77  E-value: 1.96e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  20 PALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRdVSRLPEhrratdlgrvFQDPMRGTaadmqI 99
Cdd:cd03291    51 PVLKNINLKIEKGEMLAITGSTGSGKTSLLMLILGELEPSEGKIKHSGR-ISFSSQ----------FSWIMPGT-----I 114
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 100 VENLAlaarrgesrglsWGITRDErasYRERLAELDLGLEERLTS----------KVGL-LSGGQRQALTLLMAILKKPK 168
Cdd:cd03291   115 KENII------------FGVSYDE---YRYKSVVKACQLEEDITKfpekdntvlgEGGItLSGGQRARISLARAVYKDAD 179
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2506233547 169 LLLLDEHTAALDpktaskvlALTERLVGEHGLTTLM-------VTHNMnDAIRLGNRLIMMHEGNVIF 229
Cdd:cd03291   180 LYLLDSPFGYLD--------VFTEKEIFESCVCKLManktrilVTSKM-EHLKKADKILILHEGSSYF 238
ABCD_peroxisomal_ALDP cd03223
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding ...
26-76 2.25e-04

ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding cassette transporter (Pat) is involved in the import of very long-chain fatty acids (VLCFA) into the peroxisome. The peroxisomal membrane forms a permeability barrier for a wide variety of metabolites required for and formed during fatty acid beta-oxidation. To communicate with the cytoplasm and mitochondria, peroxisomes need dedicated proteins to transport such hydrophilic molecules across their membranes. X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ALD gene, which encodes ALDP (adrenoleukodystrophy protein ), a peroxisomal integral membrane protein that is a member of the ATP-binding cassette (ABC) transporter protein family. The disease is characterized by a striking and unpredictable variation in phenotypic expression. Phenotypes include the rapidly progressive childhood cerebral form (CCALD), the milder adult form, adrenomyeloneuropathy (AMN), and variants without neurologic involvement (i.e. asymptomatic).


Pssm-ID: 213190 [Multi-domain]  Cd Length: 166  Bit Score: 40.60  E-value: 2.25e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2506233547  26 DLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVIL-DGRDVSRLPEH 76
Cdd:cd03223    21 SFEIKPGDRLLITGPSGTGKSSLFRALAGLWPWGSGRIGMpEGEDLLFLPQR 72
PRK11819 PRK11819
putative ABC transporter ATP-binding protein; Reviewed
3-55 3.08e-04

putative ABC transporter ATP-binding protein; Reviewed


Pssm-ID: 236992 [Multi-domain]  Cd Length: 556  Bit Score: 41.64  E-value: 3.08e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2506233547   3 VLKGVTKTFNkstvNEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGV 55
Cdd:PRK11819    8 TMNRVSKVVP----PKKQILKDISLSFFPGAKIGVLGLNGAGKSTLLRIMAGV 56
PRK10938 PRK10938
putative molybdenum transport ATP-binding protein ModF; Provisional
17-54 3.30e-04

putative molybdenum transport ATP-binding protein ModF; Provisional


Pssm-ID: 182852 [Multi-domain]  Cd Length: 490  Bit Score: 41.54  E-value: 3.30e-04
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 2506233547  17 NEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAG 54
Cdd:PRK10938  271 NDRPILHNLSWQVNPGEHWQIVGPNGAGKSTLLSLITG 308
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
31-110 3.98e-04

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 39.66  E-value: 3.98e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   31 PGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSRLPEHRRATDLGRVFQDPMRGTAADMQIVENLALAARRG 110
Cdd:smart00382   1 PGEVILIVGPPGSGKTTLARALARELGPPGGGVIYIDGEDILEEVLDQLLLIIVGGKKASGSGELRLRLALALARKLKPD 80
ABC_ABC_ChvD TIGR03719
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ...
4-207 4.15e-04

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.


Pssm-ID: 274744 [Multi-domain]  Cd Length: 552  Bit Score: 41.46  E-value: 4.15e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547   4 LKGVTKTFNkstvNEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGV---FalDGGQVILDGRDVSRLPEHRRAT 80
Cdd:TIGR03719   7 MNRVSKVVP----PKKEILKDISLSFFPGAKIGVLGLNGAGKSTLLRIMAGVdkdF--NGEARPQPGIKVGYLPQEPQLD 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  81 DLGRVFQDPMRGTAADMQIVENL---------------ALAARRGESRGL-----SWGITRD-ERASYRERLAELDlgle 139
Cdd:TIGR03719  81 PTKTVRENVEEGVAEIKDALDRFneisakyaepdadfdKLAAEQAELQEIidaadAWDLDSQlEIAMDALRCPPWD---- 156
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2506233547 140 erltSKVGLLSGGQRQALTLLMAILKKPKLLLLDEHTAALDpktASKVLALtERLVGEHGLTTLMVTH 207
Cdd:TIGR03719 157 ----ADVTKLSGGERRRVALCRLLLSKPDMLLLDEPTNHLD---AESVAWL-ERHLQEYPGTVVAVTH 216
Rli1 COG1245
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...
27-209 7.22e-04

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440858 [Multi-domain]  Cd Length: 592  Bit Score: 40.54  E-value: 7.22e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  27 LHLEPGDF-----VTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRdVSRLPEhrratdlgRVFQDpmrgtaADMQIVE 101
Cdd:COG1245   356 LEVEGGEIregevLGIVGPNGIGKTTFAKILAGVLKPDEGEVDEDLK-ISYKPQ--------YISPD------YDGTVEE 420
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 102 NLALAArrGESRGLSWgitrderasYRERLAElDLGLEERLTSKVGLLSGGQRQALTLLMAILKKPKLLLLDEHTAALDP 181
Cdd:COG1245   421 FLRSAN--TDDFGSSY---------YKTEIIK-PLGLEKLLDKNVKDLSGGELQRVAIAACLSRDADLYLLDEPSAHLDV 488
                         170       180       190
                  ....*....|....*....|....*....|.
gi 2506233547 182 K---TASKVLaltERLVGEHGLTTLMVTHNM 209
Cdd:COG1245   489 EqrlAVAKAI---RRFAENRGKTAMVVDHDI 516
araG PRK11288
L-arabinose ABC transporter ATP-binding protein AraG;
25-227 9.75e-04

L-arabinose ABC transporter ATP-binding protein AraG;


Pssm-ID: 183077 [Multi-domain]  Cd Length: 501  Bit Score: 40.28  E-value: 9.75e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  25 VDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVS-RLPehRRATDLGRVFQDPMR---GTAADMQIV 100
Cdd:PRK11288  272 ISFSVRAGEIVGLFGLVGAGRSELMKLLYGATRRTAGQVYLDGKPIDiRSP--RDAIRAGIMLCPEDRkaeGIIPVHSVA 349
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 101 ENLALAARRGESRGLSWGITRDERASYRERLAELDLGLEERLTsKVGLLSGGQRQALTLLMAILKKPKLLLLDEHTAALD 180
Cdd:PRK11288  350 DNINISARRHHLRAGCLINNRWEAENADRFIRSLNIKTPSREQ-LIMNLSGGNQQKAILGRWLSEDMKVILLDEPTRGID 428
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 2506233547 181 PKTASKVLALTERLvGEHGLTTLMVTHNMNDAIRLGNRLIMMHEGNV 227
Cdd:PRK11288  429 VGAKHEIYNVIYEL-AAQGVAVLFVSSDLPEVLGVADRIVVMREGRI 474
ABCG_PDR_domain2 cd03232
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding ...
19-68 1.00e-03

Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213199 [Multi-domain]  Cd Length: 192  Bit Score: 39.15  E-value: 1.00e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2506233547  19 KPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAG--VFALDGGQVILDGR 68
Cdd:cd03232    20 RQLLNNISGYVKPGTLTALMGESGAGKTTLLDVLAGrkTAGVITGEILINGR 71
PRK15439 PRK15439
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
12-225 1.03e-03

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional


Pssm-ID: 185336 [Multi-domain]  Cd Length: 510  Bit Score: 40.03  E-value: 1.03e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  12 NKSTVNEKPALTGVDL----------HLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILDGRDVSR--------- 72
Cdd:PRK15439  259 RRQQAAGAPVLTVEDLtgegfrnislEVRAGEILGLAGVVGAGRTELAETLYGLRPARGGRIMLNGKEINAlstaqrlar 338
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  73 ----LPEHRRATDLgrvFQD-PMRGTAADMqIVENLALAARRGEsrglswgitrdERASYRERLAELDLGLEErLTSKVG 147
Cdd:PRK15439  339 glvyLPEDRQSSGL---YLDaPLAWNVCAL-THNRRGFWIKPAR-----------ENAVLERYRRALNIKFNH-AEQAAR 402
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2506233547 148 LLSGGQRQALTLLMAILKKPKLLLLDEHTAALDPKTASKVLALTERlVGEHGLTTLMVTHNMNDAIRLGNRLIMMHEG 225
Cdd:PRK15439  403 TLSGGNQQKVLIAKCLEASPQLLIVDEPTRGVDVSARNDIYQLIRS-IAAQNVAVLFISSDLEEIEQMADRVLVMHQG 479
AAA_23 pfam13476
AAA domain;
24-60 1.21e-03

AAA domain;


Pssm-ID: 463890 [Multi-domain]  Cd Length: 190  Bit Score: 39.02  E-value: 1.21e-03
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 2506233547  24 GVDLHLEPGdfVTVIGG-NGAGKSTLLNSIAgvFALDG 60
Cdd:pfam13476  11 DQTIDFSKG--LTLITGpNGSGKTTILDAIK--LALYG 44
COG3950 COG3950
Predicted ATP-binding protein involved in virulence [General function prediction only];
25-57 1.23e-03

Predicted ATP-binding protein involved in virulence [General function prediction only];


Pssm-ID: 443150 [Multi-domain]  Cd Length: 276  Bit Score: 39.60  E-value: 1.23e-03
                          10        20        30
                  ....*....|....*....|....*....|....
gi 2506233547  25 VDLHLEPGDFVTVIGG-NGAGKSTLLNSIAGVFA 57
Cdd:COG3950    17 LEIDFDNPPRLTVLVGeNGSGKTTLLEAIALALS 50
ABCG_PDR_domain1 cd03233
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette ...
13-54 1.52e-03

First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213200 [Multi-domain]  Cd Length: 202  Bit Score: 38.78  E-value: 1.52e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 2506233547  13 KSTVNEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAG 54
Cdd:cd03233    14 GKGRSKIPILKDFSGVVKPGEMVLVLGRPGSGCSTLLKALAN 55
COG3910 COG3910
Predicted ATPase [General function prediction only];
20-53 1.66e-03

Predicted ATPase [General function prediction only];


Pssm-ID: 443116 [Multi-domain]  Cd Length: 239  Bit Score: 38.98  E-value: 1.66e-03
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 2506233547  20 PALTGVD-LHLEPGdfVTVI-GGNGAGKSTLLNSIA 53
Cdd:COG3910    25 PAVRNLEgLEFHPP--VTFFvGENGSGKSTLLEAIA 58
PTZ00265 PTZ00265
multidrug resistance protein (mdr1); Provisional
144-222 2.04e-03

multidrug resistance protein (mdr1); Provisional


Pssm-ID: 240339 [Multi-domain]  Cd Length: 1466  Bit Score: 39.63  E-value: 2.04e-03
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2506233547  144 SKVGLLSGGQRQALTLLMAILKKPKLLLLDEHTAALDPKTASKVLALTERLVGEHGLTTLMVTHNMNdAIRLGNRLIMM 222
Cdd:PTZ00265   575 SNASKLSGGQKQRISIARAIIRNPKILILDEATSSLDNKSEYLVQKTINNLKGNENRITIIIAHRLS-TIRYANTIFVL 652
PRK10636 PRK10636
putative ABC transporter ATP-binding protein; Provisional
17-227 3.39e-03

putative ABC transporter ATP-binding protein; Provisional


Pssm-ID: 236729 [Multi-domain]  Cd Length: 638  Bit Score: 38.61  E-value: 3.39e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  17 NEKPALTGVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQVILdgrdvsrlpehRRATDLGRVFQDPMRGTAAD 96
Cdd:PRK10636  323 GDRIILDSIKLNLVPGSRIGLLGRNGAGKSTLIKLLAGELAPVSGEIGL-----------AKGIKLGYFAQHQLEFLRAD 391
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  97 MQIVENLALAARRGESRGLswgitRDERASYrerlaeldlGLE-ERLTSKVGLLSGGQRQALTLLMAILKKPKLLLLDEH 175
Cdd:PRK10636  392 ESPLQHLARLAPQELEQKL-----RDYLGGF---------GFQgDKVTEETRRFSGGEKARLVLALIVWQRPNLLLLDEP 457
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2506233547 176 TAALDPKTASkvlALTERLVGEHGlTTLMVTHNMNDAIRLGNRLIMMHEGNV 227
Cdd:PRK10636  458 TNHLDLDMRQ---ALTEALIDFEG-ALVVVSHDRHLLRSTTDDLYLVHDGKV 505
TMPK cd01672
Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the ...
34-65 6.27e-03

Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step in either de novo or salvage biosynthesis of thymidine triphosphate (TTP).


Pssm-ID: 238835  Cd Length: 200  Bit Score: 36.86  E-value: 6.27e-03
                          10        20        30
                  ....*....|....*....|....*....|..
gi 2506233547  34 FVTVIGGNGAGKSTLLNSIAGVFALDGGQVIL 65
Cdd:cd01672     2 FIVFEGIDGAGKTTLIELLAERLEARGYEVVL 33
SbcC COG0419
DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair];
35-194 6.87e-03

DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair];


Pssm-ID: 440188 [Multi-domain]  Cd Length: 204  Bit Score: 36.91  E-value: 6.87e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  35 VTVIGG-NGAGKSTLLNSIAgvFALdGGQVILDGRDVSRLPehRRATDLGRV-------------------FQDPMRGTA 94
Cdd:COG0419    25 LNLIVGpNGAGKSTILEAIR--YAL-YGKARSRSKLRSDLI--NVGSEEASVelefehggkryrierrqgeFAEFLEAKP 99
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  95 AD-MQIVENLALAARRGESRGLswgiTRDERASYRERLAELD--LGLEERLTSK------VGLLSGGQRQALTLLMAILK 165
Cdd:COG0419   100 SErKEALKRLLGLEIYEELKER----LKELEEALESALEELAelQKLKQEILAQlsgldpIETLSGGERLRLALADLLSL 175
                         170       180
                  ....*....|....*....|....*....
gi 2506233547 166 KPKlllldehTAALDPKTASKVLALTERL 194
Cdd:COG0419   176 ILD-------FGSLDEERLERLLDALEEL 197
PRK13549 PRK13549
xylose transporter ATP-binding subunit; Provisional
25-225 7.15e-03

xylose transporter ATP-binding subunit; Provisional


Pssm-ID: 184134 [Multi-domain]  Cd Length: 506  Bit Score: 37.60  E-value: 7.15e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  25 VDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVFAldG---GQVILDGRDVS-RLPEHRRATDLGRVFQDPMR-GTAADMQI 99
Cdd:PRK13549  281 VSFSLRRGEILGIAGLVGAGRTELVQCLFGAYP--GrweGEIFIDGKPVKiRNPQQAIAQGIAMVPEDRKRdGIVPVMGV 358
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 100 VENLALAARRGESRGlswGITRDErasyrerlAELDLGLEE--RLTSK-------VGLLSGGQRQALTLLMAILKKPKLL 170
Cdd:PRK13549  359 GKNITLAALDRFTGG---SRIDDA--------AELKTILESiqRLKVKtaspelaIARLSGGNQQKAVLAKCLLLNPKIL 427
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2506233547 171 LLDEHTAALDPKTASKVLALTERLVGEhGLTTLMVTHNMNDAIRLGNRLIMMHEG 225
Cdd:PRK13549  428 ILDEPTRGIDVGAKYEIYKLINQLVQQ-GVAIIVISSELPEVLGLSDRVLVMHEG 481
ABC_RNaseL_inhibitor_domain1 cd03236
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...
30-209 7.18e-03

The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI s are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLIs have an N-terminal Fe-S domain and two nucleotide binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213203 [Multi-domain]  Cd Length: 255  Bit Score: 36.96  E-value: 7.18e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547  30 EPGDFVTVIGGNGAGKSTLLNSIAGVFALDGGQvILDGRDVSRLPEHRRATDLGRVFQDPMRGTAADMQIVENLAL--AA 107
Cdd:cd03236    24 REGQVLGLVGPNGIGKSTALKILAGKLKPNLGK-FDDPPDWDEILDEFRGSELQNYFTKLLEGDVKVIVKPQYVDLipKA 102
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2506233547 108 RRGESRGLswgITR-DERASYRERLAELDL-GLEERltsKVGLLSGGQRQALTLLMAILKKPKLLLLDEHTAALDPKTAS 185
Cdd:cd03236   103 VKGKVGEL---LKKkDERGKLDELVDQLELrHVLDR---NIDQLSGGELQRVAIAAALARDADFYFFDEPSSYLDIKQRL 176
                         170       180
                  ....*....|....*....|....
gi 2506233547 186 KVLALTERLVgEHGLTTLMVTHNM 209
Cdd:cd03236   177 NAARLIRELA-EDDNYVLVVEHDL 199
AAA_29 pfam13555
P-loop containing region of AAA domain;
24-56 7.63e-03

P-loop containing region of AAA domain;


Pssm-ID: 433304 [Multi-domain]  Cd Length: 61  Bit Score: 34.11  E-value: 7.63e-03
                          10        20        30
                  ....*....|....*....|....*....|...
gi 2506233547  24 GVDLHLEPGDFVTVIGGNGAGKSTLLNSIAGVF 56
Cdd:pfam13555  14 GHTIPIDPRGNTLLTGPSGSGKSTLLDAIQTLL 46
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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