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MULTISPECIES: TonB-dependent receptor domain-containing protein [Asaia]
Protein Classification
TonB-dependent receptor ( domain architecture ID 11446927 )
TonB dependent receptor having a carboxypeptidase regulatory-like domain, may act as a channel to allow import of extracellular nutrients, such as iron-siderophore complexes or non-Fe compounds
List of domain hits
Name
Accession
Description
Interval
E-value
CirA
COG1629 Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];
55-737
5.24e-52
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];
Pssm-ID: 441236 [Multi-domain]
Cd Length: 644
Bit Score: 192.35
E-value: 5.24e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 55 IS VT SS R RA lnggggm MRHETASH S IQTVT R QYIDM Q s PA STAL D MVKNL P S V V V STV dss G ILG GQI NS R -- SLTDSDM 132
Cdd:COG1629 4 VV VT AT R TD ------- ESLQDVPG S VSVIS R EQLED Q - PA TDLG D LLRRV P G V S V TSA --- G GGA GQI SI R gf GGGGNRV 72
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 133 GI L L DGVP VATAYYLNQN --- V D T E NLAAIS V TP G SAA i D L PVTS A AA G IM N SE T FQ P S D KF GG LMDF SYG TNNLS R EF L 209
Cdd:COG1629 73 LV L V DGVP LNDPSGGDGG lsy I D P E DIERVE V LR G PSS - A L YGSG A LG G VI N IV T KK P K D GK GG EVSA SYG SYGTY R AS L 151
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 210 RVES G aig HSGIRTYT S F S HTHARTWDGPGTNE R RH L DVGATKDFQ D GSFVN L FV S WNHQFTMA P LNP T AQQFFDKKSRV 289
Cdd:COG1629 152 SLSG G --- NGKLAYRL S A S YRDSDGYRDNSDSD R YN L RAKLGYQLG D DTRLT L SA S YSDSDQDS P GYL T LAALRPRGAMD 228
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 290 RTF N YS S SYDQA N PS D YGM L NGN mwdqvfvtlpl HVQ L PSRFS L DFKP YY V Y NGGYTYN gslfngs ATPA T VGPN G NAIS 369
Cdd:COG1629 229 DGT N PY S NDTDD N TR D RYS L SLE ----------- YEH L GDGLK L SASA YY R Y DDTDLDS ------- DFTP T PADG G TLEQ 290
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 370 GNLPAAS Y ysvyrpha G AVAK L N YD IDVHDRL T FGYWF DYQ DNQV D NRYSA L SSTGKQPFPYA S S A GIYVSGSRY mpykg 449
Cdd:COG1629 291 TDFDNRT Y -------- G LELR L T YD LGFGGKH T LLVGL DYQ RQDL D GSGYP L DLGSGSLPTLT S G A DDDGTTTSL ----- 357
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 450 dsgwkih S L FIE D DT KL l N DKL RIN AG FKI -- AMINRWSGNYASTAPRIQSNQVVPL P QAAIS Y NIDSHNMV Y VNAEGD F 527
Cdd:COG1629 358 ------- A L YAQ D TY KL - T DKL TLT AG LRY dy VSYDVDDTVTGTDSASGSRSYSAFS P SLGLT Y QLSPNLSL Y ASYSRG F 429
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 528 R M P DP G S L GQVF da QTGTY VGNP y NA KP QY S IKE ELG W R FN -- NQY L MAD L E LF NYAIT N RL LS TNVYLNNQSISSTI NA 605
Cdd:COG1629 430 R A P TF G E L YANG -- TDPYS VGNP - DL KP ET S TNY ELG L R YR ll DGR L SLS L A LF YSDVD N EI LS VPLPNDSGFSTYYT NA 506
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 606 G NQTAR GV DFMI S GHPYHHV S PFV S VE Y LN A TT D SN iattgtlngkt VGDLLPTK GN TAVQS P HVH A SA GLTY D - N G TFF 684
Cdd:COG1629 507 G KARSY GV ELEL S YQLTPGL S LNA S YS Y TD A KF D DD ----------- TDGSADLD GN RLPGV P PLT A NL GLTY E f P G GWS 575
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....
gi 2520615286 685 ANGS V S YV SSQ Y STFM N D Q KM P - GY VTDN L AI GYRF K sfgam KTPKFQ L NFS NL 737
Cdd:COG1629 576 LGLG V R YV GDR Y LDDA N T Q GA P g GY TLVD L GA GYRF G ----- DNLTLS L GVD NL 624
Name
Accession
Description
Interval
E-value
CirA
COG1629 Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];
55-737
5.24e-52
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];
Pssm-ID: 441236 [Multi-domain]
Cd Length: 644
Bit Score: 192.35
E-value: 5.24e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 55 IS VT SS R RA lnggggm MRHETASH S IQTVT R QYIDM Q s PA STAL D MVKNL P S V V V STV dss G ILG GQI NS R -- SLTDSDM 132
Cdd:COG1629 4 VV VT AT R TD ------- ESLQDVPG S VSVIS R EQLED Q - PA TDLG D LLRRV P G V S V TSA --- G GGA GQI SI R gf GGGGNRV 72
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 133 GI L L DGVP VATAYYLNQN --- V D T E NLAAIS V TP G SAA i D L PVTS A AA G IM N SE T FQ P S D KF GG LMDF SYG TNNLS R EF L 209
Cdd:COG1629 73 LV L V DGVP LNDPSGGDGG lsy I D P E DIERVE V LR G PSS - A L YGSG A LG G VI N IV T KK P K D GK GG EVSA SYG SYGTY R AS L 151
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 210 RVES G aig HSGIRTYT S F S HTHARTWDGPGTNE R RH L DVGATKDFQ D GSFVN L FV S WNHQFTMA P LNP T AQQFFDKKSRV 289
Cdd:COG1629 152 SLSG G --- NGKLAYRL S A S YRDSDGYRDNSDSD R YN L RAKLGYQLG D DTRLT L SA S YSDSDQDS P GYL T LAALRPRGAMD 228
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 290 RTF N YS S SYDQA N PS D YGM L NGN mwdqvfvtlpl HVQ L PSRFS L DFKP YY V Y NGGYTYN gslfngs ATPA T VGPN G NAIS 369
Cdd:COG1629 229 DGT N PY S NDTDD N TR D RYS L SLE ----------- YEH L GDGLK L SASA YY R Y DDTDLDS ------- DFTP T PADG G TLEQ 290
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 370 GNLPAAS Y ysvyrpha G AVAK L N YD IDVHDRL T FGYWF DYQ DNQV D NRYSA L SSTGKQPFPYA S S A GIYVSGSRY mpykg 449
Cdd:COG1629 291 TDFDNRT Y -------- G LELR L T YD LGFGGKH T LLVGL DYQ RQDL D GSGYP L DLGSGSLPTLT S G A DDDGTTTSL ----- 357
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 450 dsgwkih S L FIE D DT KL l N DKL RIN AG FKI -- AMINRWSGNYASTAPRIQSNQVVPL P QAAIS Y NIDSHNMV Y VNAEGD F 527
Cdd:COG1629 358 ------- A L YAQ D TY KL - T DKL TLT AG LRY dy VSYDVDDTVTGTDSASGSRSYSAFS P SLGLT Y QLSPNLSL Y ASYSRG F 429
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 528 R M P DP G S L GQVF da QTGTY VGNP y NA KP QY S IKE ELG W R FN -- NQY L MAD L E LF NYAIT N RL LS TNVYLNNQSISSTI NA 605
Cdd:COG1629 430 R A P TF G E L YANG -- TDPYS VGNP - DL KP ET S TNY ELG L R YR ll DGR L SLS L A LF YSDVD N EI LS VPLPNDSGFSTYYT NA 506
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 606 G NQTAR GV DFMI S GHPYHHV S PFV S VE Y LN A TT D SN iattgtlngkt VGDLLPTK GN TAVQS P HVH A SA GLTY D - N G TFF 684
Cdd:COG1629 507 G KARSY GV ELEL S YQLTPGL S LNA S YS Y TD A KF D DD ----------- TDGSADLD GN RLPGV P PLT A NL GLTY E f P G GWS 575
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....
gi 2520615286 685 ANGS V S YV SSQ Y STFM N D Q KM P - GY VTDN L AI GYRF K sfgam KTPKFQ L NFS NL 737
Cdd:COG1629 576 LGLG V R YV GDR Y LDDA N T Q GA P g GY TLVD L GA GYRF G ----- DNLTLS L GVD NL 624
ligand_gated_channel
cd01347 TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ...
79-769
1.38e-30
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.
Pssm-ID: 238657 [Multi-domain]
Cd Length: 635
Bit Score: 128.34
E-value: 1.38e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 79 S IQTV T RQY I D m QS PA STAL D MVKNL P S V V V STVDSS G il G GQ I NS R SLTDSDMGI L L DG V P V A TAY Y L ---- NQNVDT E 154
Cdd:cd01347 1 S VSVI T AED I E - KQ PA TSLA D LLRRI P G V S V TRGGGG G -- G ST I SI R GFGPDRTLV L V DG L P L A SSN Y G rgvd LNTIPP E 77
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 155 NLAAIS V TP G SAAI d L PVTS A AA G IM N SE T FQ P S D K FGG LMDFS YG TN N - L S REFLRV - E SGA IGHS G I --- R T Y TSFSH 229
Cdd:cd01347 78 LIERVE V LK G PSSA - L YGSG A IG G VV N II T KR P T D E FGG SVTAG YG SD N s G S SGGGGF d V SGA LADD G A fga R L Y GAYRD 156
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 230 THARTWDGPGTNER rhldvgatkd FQDGSF V NLFVS W N hqftmap LNPTAQQFF D kksrvrt FN Y sss Y DQ ANPSDY G M L 309
Cdd:cd01347 157 GDGTIDGDGQADDS ---------- DEERYN V AGKLD W R ------- PDDDTRLTL D ------- AG Y --- Q DQ DADGPG G T L 209
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 310 NG N MWDQVFVTL P LHVQLPS R FSLDFKP Y YVYNG - G YTYNGSLFNGS atpatvgpngna ISG NL PAASYYSVYR P HAGAV 388
Cdd:cd01347 210 PA N GTGSSLGGG P SSNTNGD R DWDYRDR Y RKRAS l G LEHDLNDTGWT ------------ LRA NL SYSYTDNDGD P LILNG 277
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 389 A k L N YDIDVHD R LTFGYWF D YQDNQV D NRYS A LSS TG KQPF pyassag IYVS G SR Y MPYKG D S gw K IHS L FIE D DTK L l N 468
Cdd:cd01347 278 G - N N AAGGDLG R SGYSSER D TTQLGF D AGLN A PFG TG PVAH ------- TLTL G VE Y RREEL D E -- K QTA L YAQ D TIE L - T 346
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 469 D K L RINA G FKIAMINRW S GNYASTAPRIQSNQVVPL P QAAIS Y NIDSHNMV Y VNAEGD FR M P DP G S L GQVFDAQTGTY VG 548
Cdd:cd01347 347 D D L TLTL G LRYDHYDQD S KDTIAGGTTAKKSYSHWS P SLGLV Y KLTDGLSL Y ASYSQG FR A P SL G E L YGGGSHGGTAA VG 426
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 549 NP y N A KP QY S IKE ELG WRFNNQY - L MADLE LF NYA I T N RLL ST NVYLNNQSISSTI N A G NQTA RGV DFMI S GHPYHHVSP 627
Cdd:cd01347 427 NP - N L KP EK S KQY ELG LKYDPGD g L TLSAA LF RID I K N EIV ST PTNTGLGLVTVYV N G G KARI RGV ELEA S YDLTDGLGL 505
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 628 FV S VE Y LNA ttd SNIA T T G TLN G KTVGDLLPTKG N TAVQ ---- SPHVH A SA G LT Y DNGTF fangsvsyvs SQYSTFM N DQ 703
Cdd:cd01347 506 TG S YT Y TDT --- EVKR T D G ATT G NRLPGIPKHTA N LGLD yelp DEGLT A GG G VR Y RGKQY ---------- ADTANGN N TV 572
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2520615286 704 K M PGY VTDN L AIG Y R F K sfgam K TPKFQ L NFS NL GGSFIR T GV S GLVANAQTTK G i Y G S T VSA S G S 769
Cdd:cd01347 573 K V PGY TLVD L SAS Y Q F T ----- K NLTLR L GVN NL FDKDYY T SL S VRGSGLYGYY G - P G R T YYL S V S 632
TonB-siderophor
TIGR01783 TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of ...
79-770
1.04e-20
TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of TonB-dependent outer membrane siderophore receptors. It has no overlap with TonB receptors known to transport other substances, but is likely incomplete due to lack of characterizations. It is likely that genuine siderophore receptors will be identified which score below the noise cutoff to this model at which point the model should be updated. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]
Pssm-ID: 273805 [Multi-domain]
Cd Length: 651
Bit Score: 97.10
E-value: 1.04e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 79 S IQTV TRQ YID m QSP A STALDMVKNL P S VVV STVDSSGIL G GQ - I NSRS L TDSDMGIL LDGVP v ATAYYLNQN VD TENLA 157
Cdd:TIGR01783 5 S VSVI TRQ ELE - DQQ A GSLSEALQRV P G VVV GGSGGTTQF G NI t I RGFG L EVDIDNVY LDGVP - LLSRGNLAI VD PAMVE 82
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 158 AIS V TP G S A AI d L PVT SA AA G IM N SE T FQ P S D KFG G LMD F SY GT NNLS R EFLRVESGAIGHSGI R TYTSFSHTHARTW - D 236
Cdd:TIGR01783 83 RVE V LR G P A SL - L YGG SA PG G VI N IV T KR P Q D EPK G SVT F GA GT RSGY R TAFDLGGPLGADGTF R GRLNGARQDGDSF y D 161
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 237 G P G tn E RRH L DVG AT k D F Q DGSFVN L FVSWNH Q FTMAPLNPTAQQF --- FDKKSRVRTFNYSS S ---- YD QANPSD YG ML 309
Cdd:TIGR01783 162 G A G -- E ETR L GAT AT - D W Q LDDRTL L RLGAYY Q KERDRGGYGGLPA sgg TSGRDLSSDRYLGT S snrn YD DREYLS YG LS 238
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 310 NGNMWDQ V FV tlpl HV Q LPSRFSL D FKPYY V YNG GY TYN G S LF NG S A T PAT V GPNGNA I SGN L PA asyysvyrphagava 389
Cdd:TIGR01783 239 LEYQFND V WT ---- GK Q NLRYSYF D TDSNQ V QAS GY SSD G G LF GR S L T VVN V KQDRVQ I DAG L DG --------------- 299
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 390 kl NYDIDVHDRLTFGYWFDY Q DNQVDNRYSALS S TGKQPFPYA SSA G i YVS G SRYMPYKGD S GW K IHSLFIEDD t K LL N D 469
Cdd:TIGR01783 300 -- EFETGPIEHDLLLGVSYG Q RTTNRFNNTGYP S DNIYSLTAT SSA R - TDI G DSPKDRALS S TT K ALNGVALQR - I LL A D 375
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 470 K LRINA G -- FKIAMINRWS G NYA ST AP R i QSN Q V vp L P QAAIS Y NIDSHNMV Y VNAEGD F RMPDPGSL G QVFDA qtgtyv 547
Cdd:TIGR01783 376 K WTLTL G gr YDSVDVKSNN G VAG ST GK R - DDS Q F -- T P SLGVA Y KPTDDWSL Y ASYAES F KPGGYYPK G AGNSG ------ 446
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 548 gnp YNAK P QYSIKE ELG W R FNNQ - Y L M A DLE LF N ya IT NRLLSTN v YLN N QSI S st I NAG NQTA RGV DFMIS G HPYHHV S 626
Cdd:TIGR01783 447 --- DILE P EKGKNY ELG V R YDLG d S L L A TAA LF R -- IT KDNQLVQ - DPV N GTF S -- V NAG KTRN RGV ELEAR G YLTPGL S 518
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 627 PFVSVE Y LN A -- T T D S N IA T T gtlngktvgdllptk GNT AVQS P HVH AS AGLT Y D ------ NG T FFANGSVSYVSSQYST 698
Cdd:TIGR01783 519 LSAGYT Y TD A ef T E D T N GD T Q --------------- GNT VPFV P KHT AS LWAS Y A ppvgdn GL T LGGGVQYTGKAYVDGG 583
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2520615286 699 fm N DQ K M P G Y VTDN L AIG Y R fks FGAM K TPKFQ LN FS NL GGSFIR T GVSGLVAN A QTTK G I y GS TV SA S G S P 770
Cdd:TIGR01783 584 -- N TG K V P S Y TVVD L SVR Y D --- LTKK K NLTLA LN VN NL FDRDYY T SGYRWGPS A YIYP G A - PR TV GL S V S Y 649
TonB_dep_Rec
pfam00593 TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
288-737
2.93e-18
TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
Pssm-ID: 395474 [Multi-domain]
Cd Length: 475
Bit Score: 88.67
E-value: 2.93e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 288 RVRTFN Y SSSY D QANPS D YGMLN G NMWDQVFVTLPLHVQLPS R FS L DFKPY Y VYNG G YTYNGS L FN G SATPATV G PNGNA 367
Cdd:pfam00593 18 GYDYSR Y TDGL D LGLTL D GYGND G GYLGDRPLYYGRDYSDTD R KR L SLGYD Y DLGD G LSWLST L RL G LRYSSLD G DYTSN 97
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 368 I SG NLP A AS Y Y S VY R PHAGAV ak L NY D IDVHDR L TFGYWFDYQDNQVDNR Y SA L SSTGKQ P FPY A SSAGIYV S GSRY mpy 447
Cdd:pfam00593 98 S SG LSG A GD Y L S DD R LYGLYG -- L DG D LELSLD L SHDLLLGVELRTAGLD Y RR L DDDAYD P YDP A NPSSSSY S DTTT --- 172
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 448 kgdsgw KIHS L FIE D DT KL l N D K L RINA G FKIAMINRWSGNYASTAPRIQSNQVVPL P QAAIS Y NIDSHNMV Y VNAEGD F 527
Cdd:pfam00593 173 ------ DSYG L YLQ D NI KL - T D R L TLTL G LRYDHYSTDGDDGNGGGDNFSRSYSAFS P RLGLV Y KPTDNLSL Y ASYSRG F 245
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 528 R M P DP G S L - G QVFDAQT G TYV G NPYNA KP QY S IKE ELG WRFNNQY L MAD L E LF NYA I T N RLL S - TNVYLNNQSISSTI N A 605
Cdd:pfam00593 246 R A P SL G E L y G SGSGGGG G AVA G GNPDL KP ET S DNY ELG LKYDDGR L SLS L A LF YID I K N LIT S d PDGPGLGGTVYTYT N V 325
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 606 G NQTA RGV DFMI SG HPYHHVSPFVSVE Y LN A TT D SNIAT T gtlngktvgdllptk GN TAVQS P HVH A SA GLTYD -- N G TF 683
Cdd:pfam00593 326 G KARI RGV ELEL SG RLWGLGLSGGGYT Y TD A DD D ADADD T --------------- GN PLPNV P RHT A NL GLTYD fp L G GW 390
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*..
gi 2520615286 684 F A NGSVS YV S S QYSTFMNDQ --- K M PGY VTDN L AI GYR FK sfgam K TPKFQ L NFS NL 737
Cdd:pfam00593 391 G A RLGAR YV G S GERRYGDAA ntf K T PGY TLVD L SA GYR LN ----- K NLTLR L GVN NL 442
Name
Accession
Description
Interval
E-value
CirA
COG1629 Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];
55-737
5.24e-52
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];
Pssm-ID: 441236 [Multi-domain]
Cd Length: 644
Bit Score: 192.35
E-value: 5.24e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 55 IS VT SS R RA lnggggm MRHETASH S IQTVT R QYIDM Q s PA STAL D MVKNL P S V V V STV dss G ILG GQI NS R -- SLTDSDM 132
Cdd:COG1629 4 VV VT AT R TD ------- ESLQDVPG S VSVIS R EQLED Q - PA TDLG D LLRRV P G V S V TSA --- G GGA GQI SI R gf GGGGNRV 72
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 133 GI L L DGVP VATAYYLNQN --- V D T E NLAAIS V TP G SAA i D L PVTS A AA G IM N SE T FQ P S D KF GG LMDF SYG TNNLS R EF L 209
Cdd:COG1629 73 LV L V DGVP LNDPSGGDGG lsy I D P E DIERVE V LR G PSS - A L YGSG A LG G VI N IV T KK P K D GK GG EVSA SYG SYGTY R AS L 151
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 210 RVES G aig HSGIRTYT S F S HTHARTWDGPGTNE R RH L DVGATKDFQ D GSFVN L FV S WNHQFTMA P LNP T AQQFFDKKSRV 289
Cdd:COG1629 152 SLSG G --- NGKLAYRL S A S YRDSDGYRDNSDSD R YN L RAKLGYQLG D DTRLT L SA S YSDSDQDS P GYL T LAALRPRGAMD 228
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 290 RTF N YS S SYDQA N PS D YGM L NGN mwdqvfvtlpl HVQ L PSRFS L DFKP YY V Y NGGYTYN gslfngs ATPA T VGPN G NAIS 369
Cdd:COG1629 229 DGT N PY S NDTDD N TR D RYS L SLE ----------- YEH L GDGLK L SASA YY R Y DDTDLDS ------- DFTP T PADG G TLEQ 290
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 370 GNLPAAS Y ysvyrpha G AVAK L N YD IDVHDRL T FGYWF DYQ DNQV D NRYSA L SSTGKQPFPYA S S A GIYVSGSRY mpykg 449
Cdd:COG1629 291 TDFDNRT Y -------- G LELR L T YD LGFGGKH T LLVGL DYQ RQDL D GSGYP L DLGSGSLPTLT S G A DDDGTTTSL ----- 357
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 450 dsgwkih S L FIE D DT KL l N DKL RIN AG FKI -- AMINRWSGNYASTAPRIQSNQVVPL P QAAIS Y NIDSHNMV Y VNAEGD F 527
Cdd:COG1629 358 ------- A L YAQ D TY KL - T DKL TLT AG LRY dy VSYDVDDTVTGTDSASGSRSYSAFS P SLGLT Y QLSPNLSL Y ASYSRG F 429
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 528 R M P DP G S L GQVF da QTGTY VGNP y NA KP QY S IKE ELG W R FN -- NQY L MAD L E LF NYAIT N RL LS TNVYLNNQSISSTI NA 605
Cdd:COG1629 430 R A P TF G E L YANG -- TDPYS VGNP - DL KP ET S TNY ELG L R YR ll DGR L SLS L A LF YSDVD N EI LS VPLPNDSGFSTYYT NA 506
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 606 G NQTAR GV DFMI S GHPYHHV S PFV S VE Y LN A TT D SN iattgtlngkt VGDLLPTK GN TAVQS P HVH A SA GLTY D - N G TFF 684
Cdd:COG1629 507 G KARSY GV ELEL S YQLTPGL S LNA S YS Y TD A KF D DD ----------- TDGSADLD GN RLPGV P PLT A NL GLTY E f P G GWS 575
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....
gi 2520615286 685 ANGS V S YV SSQ Y STFM N D Q KM P - GY VTDN L AI GYRF K sfgam KTPKFQ L NFS NL 737
Cdd:COG1629 576 LGLG V R YV GDR Y LDDA N T Q GA P g GY TLVD L GA GYRF G ----- DNLTLS L GVD NL 624
ligand_gated_channel
cd01347 TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ...
79-769
1.38e-30
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.
Pssm-ID: 238657 [Multi-domain]
Cd Length: 635
Bit Score: 128.34
E-value: 1.38e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 79 S IQTV T RQY I D m QS PA STAL D MVKNL P S V V V STVDSS G il G GQ I NS R SLTDSDMGI L L DG V P V A TAY Y L ---- NQNVDT E 154
Cdd:cd01347 1 S VSVI T AED I E - KQ PA TSLA D LLRRI P G V S V TRGGGG G -- G ST I SI R GFGPDRTLV L V DG L P L A SSN Y G rgvd LNTIPP E 77
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 155 NLAAIS V TP G SAAI d L PVTS A AA G IM N SE T FQ P S D K FGG LMDFS YG TN N - L S REFLRV - E SGA IGHS G I --- R T Y TSFSH 229
Cdd:cd01347 78 LIERVE V LK G PSSA - L YGSG A IG G VV N II T KR P T D E FGG SVTAG YG SD N s G S SGGGGF d V SGA LADD G A fga R L Y GAYRD 156
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 230 THARTWDGPGTNER rhldvgatkd FQDGSF V NLFVS W N hqftmap LNPTAQQFF D kksrvrt FN Y sss Y DQ ANPSDY G M L 309
Cdd:cd01347 157 GDGTIDGDGQADDS ---------- DEERYN V AGKLD W R ------- PDDDTRLTL D ------- AG Y --- Q DQ DADGPG G T L 209
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 310 NG N MWDQVFVTL P LHVQLPS R FSLDFKP Y YVYNG - G YTYNGSLFNGS atpatvgpngna ISG NL PAASYYSVYR P HAGAV 388
Cdd:cd01347 210 PA N GTGSSLGGG P SSNTNGD R DWDYRDR Y RKRAS l G LEHDLNDTGWT ------------ LRA NL SYSYTDNDGD P LILNG 277
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 389 A k L N YDIDVHD R LTFGYWF D YQDNQV D NRYS A LSS TG KQPF pyassag IYVS G SR Y MPYKG D S gw K IHS L FIE D DTK L l N 468
Cdd:cd01347 278 G - N N AAGGDLG R SGYSSER D TTQLGF D AGLN A PFG TG PVAH ------- TLTL G VE Y RREEL D E -- K QTA L YAQ D TIE L - T 346
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 469 D K L RINA G FKIAMINRW S GNYASTAPRIQSNQVVPL P QAAIS Y NIDSHNMV Y VNAEGD FR M P DP G S L GQVFDAQTGTY VG 548
Cdd:cd01347 347 D D L TLTL G LRYDHYDQD S KDTIAGGTTAKKSYSHWS P SLGLV Y KLTDGLSL Y ASYSQG FR A P SL G E L YGGGSHGGTAA VG 426
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 549 NP y N A KP QY S IKE ELG WRFNNQY - L MADLE LF NYA I T N RLL ST NVYLNNQSISSTI N A G NQTA RGV DFMI S GHPYHHVSP 627
Cdd:cd01347 427 NP - N L KP EK S KQY ELG LKYDPGD g L TLSAA LF RID I K N EIV ST PTNTGLGLVTVYV N G G KARI RGV ELEA S YDLTDGLGL 505
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 628 FV S VE Y LNA ttd SNIA T T G TLN G KTVGDLLPTKG N TAVQ ---- SPHVH A SA G LT Y DNGTF fangsvsyvs SQYSTFM N DQ 703
Cdd:cd01347 506 TG S YT Y TDT --- EVKR T D G ATT G NRLPGIPKHTA N LGLD yelp DEGLT A GG G VR Y RGKQY ---------- ADTANGN N TV 572
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2520615286 704 K M PGY VTDN L AIG Y R F K sfgam K TPKFQ L NFS NL GGSFIR T GV S GLVANAQTTK G i Y G S T VSA S G S 769
Cdd:cd01347 573 K V PGY TLVD L SAS Y Q F T ----- K NLTLR L GVN NL FDKDYY T SL S VRGSGLYGYY G - P G R T YYL S V S 632
FepA
COG4771 Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and ...
55-720
2.62e-30
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism];
Pssm-ID: 443803 [Multi-domain]
Cd Length: 612
Bit Score: 127.28
E-value: 2.62e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 55 IS VT SS R RA lnggggm MRHET A SH S IQTV T RQY I D m QSP A STAL D MVKN LP S V V V STVDSS G I l GGQ I NS R S L TDSDMGI 134
Cdd:COG4771 30 VV VT AT R TE ------- QSLSD A PA S VSVI T AEE I E - KLG A TDLA D ALRL LP G V S V TRSGGR G G - SSG I SI R G L GGDRVLV 100
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 135 L L DGVPV ATAYYLN ---- QNVDTENLAA I S V TP G S A AIDLP v TS A AA G IM N SE T FQ P S D KFG G LMDFS YG T N NLSREFLR 210
Cdd:COG4771 101 L I DGVPV NNPALGG ggdl SYIPPDDIER I E V IR G P A SALYG - SD A IG G VI N II T KK P T D ELE G SVSLG YG S N GNGTYSGS 179
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 211 VE - S G AIGHSGIRTYT S FSHTHA ---- R TWDGP G TNERRHLDVG A TKDFQDGSFVN L FV S WN hqftmaplnptaqq FFDK 285
Cdd:COG4771 180 LS l G G PGDKLSFLLSG S YRDRDG yldy R NGGFV G NSGYERYNLN A KLGYRLSDNHR L SL S GG -------------- YSRQ 245
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 286 KSRVRTFNYSSSYDQANPSDYGMLNGNMWD qvfvt LP L HVQLPSRFS LD FKP YY VYNGGYTY NGSL FNG sa T PATVGPNG 365
Cdd:COG4771 246 DRDGGPPTLGDTEISSDNAGDRDTTTDRGN ----- YS L RYNGDLGDN LD LSL YY SRTDRDST NGSL GGS -- T GSFSDSDD 318
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 366 NAISGN L paasyysvyrphagava K L N Y DIDVHDR LT F G yw FD Y QDNQV D NRYSALSSTGKQ pfpyassagiyvsgsrym 445
Cdd:COG4771 319 TTYGLE L ----------------- D L T Y PLGGNHT LT L G -- AE Y RYDDL D SSSFLGGADASR ------------------ 361
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 446 pykgdsgw KIHS LF IE D DT KL l N DKL RIN AG F kiamin R WSGNYAST A priq SN QVVPL P QAAIS Y NIDSHNMVYVNAEG 525
Cdd:COG4771 362 -------- DTYG LF AQ D EW KL - T DKL TLT AG L ------ R YDYYSTFG A ---- SN YTAFS P RLGLR Y DLSDNLTLRASYGR 422
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 526 D FR M P DPGS L GQVFDAQT G T YV - GNP y NA KP QY S IKE ELG -- W R FN N QY L MAD L EL F NYA I TNRLLSTN V YLNNQSISST 602
Cdd:COG4771 423 G FR A P SLAE L YGSGTGTP G R YV l GNP - DL KP ET S DNY ELG le Y R LG N GG L SLS L TG F YTD I KDLIVLVP V GPGPGDVLQY 501
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 603 I N A G NQTAR G VDFMISGHPYHHVSPFV S VE YL NATT D SN iattgtlngktvgdllp TK G NTAVQS P HVH A SA GL T Y DNG - 681
Cdd:COG4771 502 E N V G KARTY G LELELKYRLGKGLTLTA S YT YL DSKI D DG ----------------- DT G EPLPNV P PHK A NL GL D Y RLP k 564
650 660 670 680
....*....|....*....|....*....|....*....|..
gi 2520615286 682 --- TFFANGSVSYVSSQYSTFMNDQKM PGY VTDN L AIG Y RFK 720
Cdd:COG4771 565 wwl LLLLTRYYGGRYVTPPSGRLEGYT PGY TLLD L RAS Y KLT 606
FecA
COG4772 Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];
134-720
5.94e-24
Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];
Pssm-ID: 443804 [Multi-domain]
Cd Length: 681
Bit Score: 107.71
E-value: 5.94e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 134 I L L DG V P V A T A Y Y ---- LNQNV D T E NLAA I S V TP G S AA I d LPVTSAAA G IM N SE T FQPSDK FGG LMDFSY G TNNLS R EFL 209
Cdd:COG4772 100 L L E DG I P I A P A P Y gdpa AYYFP D L E RMER I E V LR G A AA L - RYGPQTVG G AI N FV T RTIPTA FGG ELRVTG G SFGYR R THA 178
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 210 R V e S G AI G HS G I rt YTSF S HTHA rtw DG -- PGTNERRH --- LDV G A tk DFQ D GSFVN L FVSWNHQFTMA P LNP T AQ QF fd 284
Cdd:COG4772 179 S V - G G TV G NF G Y -- LVEY S RKRG --- DG fr DNSGFDIN dfn AKL G Y -- RLS D RQELT L KFQYYDEDANT P GGL T DA QF -- 248
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 285 kksrvrtfnysssyd Q A N P SDYGMLNGNM - WDQVFVT L PLHV QL PSRFS L DFKP YY VY nggytyng SLF N GSATPA T VG P 363
Cdd:COG4772 249 --------------- D A D P RQSYRPADQF d TRRTQLS L RYEH QL SDNTT L TTTA YY ND -------- FSR N WYIRQN T AD P 305
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 364 N GNAISGNLPAAS Y Y S V yrpha G AVAK L NYDID --- V HDR L TF G YWF d YQDNQVDNR Y SALSST G KQPFPYASS agi YVS 440
Cdd:COG4772 306 N TPGLGLRGNPRG Y R S Y ----- G IEPR L THRFE lgg V PHT L EV G LRY - HREEEDRKQ Y VNTYGQ G RSGAGLRRD --- RRF 376
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 441 GSRY mpykgdsgwki HSLFIEDDTK L l NDK L RINA G FKIAM I N R WSGNY --- ASTAPRIQ SN QV - VP LP QAAIS Y NIDSH 516
Cdd:COG4772 377 SADA ----------- LAAYAQNRFE L - TGR L TLTP G LRYEH I R R DRTDR yst RTGGDDSG SN SY s EF LP GLGLL Y QLTDN 444
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 517 NMV Y V N AEGD F RM P DP G S L GQV fdaqtgty V G NPYNA KP QY S IKE ELG W R FN - NQY L M A DLE LF NYAIT N R L L S TNV yl N 595
Cdd:COG4772 445 LQL Y A N VSRG F EP P TF G D L AYG -------- N G GNPDL KP EK S WNY ELG T R GR i GNG L S A EVA LF YIDYD N E L G S CSA -- A 514
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 596 NQSI S STI NAG NQTAR G VDFMISGHPY ---- HHVSP F VSVE Y LN A TTD S NIAT tgtlngktvgdll PTK GN TAVQS P HVH 671
Cdd:COG4772 515 GGDR S TFT NAG ETRHQ G LELALDYDLL kggg LGLPL F AAYT Y TD A EFT S DFGP ------------- VFA GN RLPYV P RHQ 581
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....*
gi 2520615286 672 AS AGL T Y DN G TFF AN GSVS YVS S Q YSTFM N ------ DQ K M P G Y VTDN L AIG Y R F K 720
Cdd:COG4772 582 LT AGL G Y EH G GWT AN LNGR YVS E Q FTDAA N tvadgs FG K I P S Y TVLD L SAS Y D F G 636
Fiu
COG4774 Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism];
79-737
1.69e-21
Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism];
Pssm-ID: 443806 [Multi-domain]
Cd Length: 639
Bit Score: 99.57
E-value: 1.69e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 79 S IQT VTR QY I DM Q S p A STAL D MVK N L P S V VVSTVD ss G IL G GQINS R SLTD S D m G I LL DG VPVATA Y ylnq NV DT E NL AA 158
Cdd:COG4774 12 S VTV VTR EL I ED Q G - A TSLA D ALR N V P G V TFGAGE -- G GN G DSFSI R GFSA S G - D I YV DG LRDPGQ Y ---- RR DT F NL ER 83
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 159 IS V TP G S A AI d L PVTSAAA G IM N SE T FQ P S D KFGGLMDFS YG TNNLS R EF L R V e S G AI G - HSGI R T yt SFSHTHARTWDG 237
Cdd:COG4774 84 VE V LK G P A SV - L YGRGSPG G VI N LV T KR P T D EPFTEVTLT YG SDGQR R AT L D V - N G PL G d DLAY R L -- NGMYRDSDSYRD 159
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 238 PGT N E R RHLDVGA T KDFQ D GSFVN L FVSWNHQFTMA ---- P LNPTAQQF fd KKS R VRTFNYSSS Y DQAN p S D YGM L NGN m 313
Cdd:COG4774 160 GVD N D R WGIAPSL T WRLG D RTRLT L DYEYQDDDRTP dygv P AVANGRPV -- DVD R STFYGQPDD Y SDSE - T D SAT L RLE - 235
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 314 wdqvfvtlpl H vqlps R F SLDFK pyy VY N GGYTYNGSLFNGSAT P ATVGPN G NAISGNLPAASYYSVY rpha GAVAK L NY 393
Cdd:COG4774 236 ---------- H ----- D F NDNWT --- LR N ALRYSDYDRDYRNTY P TGGNAT G TVTRSAYRRDQDNDTL ---- SNQTD L TG 293
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 394 DI D --- V HDR L TF G yw FD Y QDNQV DN - RYS ALSSTGKQP f P Y ASSA G IY V S G SRYMPYKG DS GWKIHS L FIE D DTK L l N D 469
Cdd:COG4774 294 KF D tgg V KHT L LA G -- VE Y SREDS DN a RYS GGGTAPTVN - L Y NPVY G AP V T G PTLGGADN DS RTDTTG L YLQ D TIS L - T D 369
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 470 KLRIN AG F kiamin R W ------ SGNYAST A PRIQSNQVVPL P Q A AIS Y NIDSHNMV Y VN - AEG dfrmpdpgslgqv F DAQ 542
Cdd:COG4774 370 RWSLL AG L ------ R Y drfdtd YTDRTTG A TTSSYDDSAFS P R A GLV Y KPTPNLSL Y AS y STS ------------- F NPG 430
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 543 T G TYVGNPYNA -- K P QY S IKE E L G -- W RFNNQY L MADLE LF N ya I TN rlls TNV YLNNQSISS - TINA G N Q TA RGV DFMI 617
Cdd:COG4774 431 G G APSLSNAGQ al D P EK S RQY E V G vk W DLLDGR L SLTAA LF R -- I EK ---- TNV RTTDPANPG v YVQT G E Q RS RGV ELEA 504
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 618 S G HPYHHV S PFVSVE YL N A - T T D S NI A TT gtlngktvgdllpt K GN TAVQS P HVH AS AGL TYD -- NGTFFAN G S V S YV S S 694
Cdd:COG4774 505 T G ELTPGW S VLAGYT YL D A e I T K S AN A AN -------------- V GN RLPNV P RHS AS LWT TYD lp LPGLTLG G G V R YV G S 570
650 660 670 680
....*....|....*....|....*....|....*....|...
gi 2520615286 695 Q Y STFM N DQ K M P G Y VTDNLAIG YR FK sfgam K TPKFQ LN FS NL 737
Cdd:COG4774 571 R Y ADAA N TV K L P S Y TRFDAGAS YR LN ----- K NLTLR LN VN NL 608
TonB-siderophor
TIGR01783 TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of ...
79-770
1.04e-20
TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of TonB-dependent outer membrane siderophore receptors. It has no overlap with TonB receptors known to transport other substances, but is likely incomplete due to lack of characterizations. It is likely that genuine siderophore receptors will be identified which score below the noise cutoff to this model at which point the model should be updated. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]
Pssm-ID: 273805 [Multi-domain]
Cd Length: 651
Bit Score: 97.10
E-value: 1.04e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 79 S IQTV TRQ YID m QSP A STALDMVKNL P S VVV STVDSSGIL G GQ - I NSRS L TDSDMGIL LDGVP v ATAYYLNQN VD TENLA 157
Cdd:TIGR01783 5 S VSVI TRQ ELE - DQQ A GSLSEALQRV P G VVV GGSGGTTQF G NI t I RGFG L EVDIDNVY LDGVP - LLSRGNLAI VD PAMVE 82
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 158 AIS V TP G S A AI d L PVT SA AA G IM N SE T FQ P S D KFG G LMD F SY GT NNLS R EFLRVESGAIGHSGI R TYTSFSHTHARTW - D 236
Cdd:TIGR01783 83 RVE V LR G P A SL - L YGG SA PG G VI N IV T KR P Q D EPK G SVT F GA GT RSGY R TAFDLGGPLGADGTF R GRLNGARQDGDSF y D 161
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 237 G P G tn E RRH L DVG AT k D F Q DGSFVN L FVSWNH Q FTMAPLNPTAQQF --- FDKKSRVRTFNYSS S ---- YD QANPSD YG ML 309
Cdd:TIGR01783 162 G A G -- E ETR L GAT AT - D W Q LDDRTL L RLGAYY Q KERDRGGYGGLPA sgg TSGRDLSSDRYLGT S snrn YD DREYLS YG LS 238
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 310 NGNMWDQ V FV tlpl HV Q LPSRFSL D FKPYY V YNG GY TYN G S LF NG S A T PAT V GPNGNA I SGN L PA asyysvyrphagava 389
Cdd:TIGR01783 239 LEYQFND V WT ---- GK Q NLRYSYF D TDSNQ V QAS GY SSD G G LF GR S L T VVN V KQDRVQ I DAG L DG --------------- 299
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 390 kl NYDIDVHDRLTFGYWFDY Q DNQVDNRYSALS S TGKQPFPYA SSA G i YVS G SRYMPYKGD S GW K IHSLFIEDD t K LL N D 469
Cdd:TIGR01783 300 -- EFETGPIEHDLLLGVSYG Q RTTNRFNNTGYP S DNIYSLTAT SSA R - TDI G DSPKDRALS S TT K ALNGVALQR - I LL A D 375
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 470 K LRINA G -- FKIAMINRWS G NYA ST AP R i QSN Q V vp L P QAAIS Y NIDSHNMV Y VNAEGD F RMPDPGSL G QVFDA qtgtyv 547
Cdd:TIGR01783 376 K WTLTL G gr YDSVDVKSNN G VAG ST GK R - DDS Q F -- T P SLGVA Y KPTDDWSL Y ASYAES F KPGGYYPK G AGNSG ------ 446
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 548 gnp YNAK P QYSIKE ELG W R FNNQ - Y L M A DLE LF N ya IT NRLLSTN v YLN N QSI S st I NAG NQTA RGV DFMIS G HPYHHV S 626
Cdd:TIGR01783 447 --- DILE P EKGKNY ELG V R YDLG d S L L A TAA LF R -- IT KDNQLVQ - DPV N GTF S -- V NAG KTRN RGV ELEAR G YLTPGL S 518
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 627 PFVSVE Y LN A -- T T D S N IA T T gtlngktvgdllptk GNT AVQS P HVH AS AGLT Y D ------ NG T FFANGSVSYVSSQYST 698
Cdd:TIGR01783 519 LSAGYT Y TD A ef T E D T N GD T Q --------------- GNT VPFV P KHT AS LWAS Y A ppvgdn GL T LGGGVQYTGKAYVDGG 583
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2520615286 699 fm N DQ K M P G Y VTDN L AIG Y R fks FGAM K TPKFQ LN FS NL GGSFIR T GVSGLVAN A QTTK G I y GS TV SA S G S P 770
Cdd:TIGR01783 584 -- N TG K V P S Y TVVD L SVR Y D --- LTKK K NLTLA LN VN NL FDRDYY T SGYRWGPS A YIYP G A - PR TV GL S V S Y 649
FhuE
COG4773 Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion ...
79-737
3.39e-20
Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion transport and metabolism];
Pssm-ID: 443805 [Multi-domain]
Cd Length: 692
Bit Score: 95.73
E-value: 3.39e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 79 S IQT VTRQ Y I DM Q S p A S T AL D MVK N L P S V V VS TV D ss G ILGGQINS R SLTDS dm GI L L DG V P VAT ay YLNQNV DT E NL AA 158
Cdd:COG4773 68 S VSV VTRQ L I ED Q G - A T T LD D ALR N V P G V T VS SY D -- G GGRDSFSI R GFSID -- NY L R DG L P LGG -- FGGGQP DT A NL ER 140
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 159 IS V TP G S A AI d L PVTSAAA G IM N SE T FQ P SDKFG G LMDF S Y G TNNLS R EFLR V e S G AIGHS G - I R TYTSFSHTHARTWDG 237
Cdd:COG4773 141 VE V LK G P A GL - L YGAGSPG G LV N LV T KR P TAEPQ G EVSL S A G SWDTY R ATAD V - G G PLNED G t L R YRLNAAYEDGDSFRD 218
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 238 PGT N E R RHLDVGATK D FQ D GSFVN L FVSWNHQ ftma PLNPTAQQFFDKKSRV --- R TF N YSSSY D QAN psdygmlngnm W 314
Cdd:COG4773 219 GVD N R R TLIAPSLDW D LT D DTTLT L GAEYQDD ---- DSTGDRGFLPLDGTLL dlp R ST N LGEPW D YYD ----------- T 283
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 315 DQVFVTLP L HVQLPSRF SL DFK p YYVYNGGYTYNGSLFN G SATP AT vgpngnais G N L PAASYYSVYRPHAGAV - A K LN Y 393
Cdd:COG4773 284 ETTTLFAE L EHRFNDDW SL RAN - ARYSDSDRDGRSAYAY G APDA AT --------- G T L TRYASARDGDSRSDSL d A N LN G 353
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 394 DID --- VHDR L TF G yw F DY QDNQV D NRYSALS stgkq PFPYASSAGIYVSGSRYMPYKG D SGWKIHS L FIE D DTK L l N D K 470
Cdd:COG4773 354 KFE tgg LEHT L LV G -- A DY SRYDS D SDSATAG ----- TINIYNPVYGNLPEPDFDASDT D TTTRQTG L YAQ D QIS L - T D R 425
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 471 L RINA G FKIAMINRW S G N YASTAPRIQSNQVV p L P Q A AIS Y NIDSHNMV Y VN - A E G d F RMPDP - GSL G QVF D AQ TG T yvg 548
Cdd:COG4773 426 L SLLL G GRYDWYETD S T N RLGGSTTSYDDSAF - T P R A GLV Y DLTPGLSL Y AS y S E S - F EPQSG a DNN G NPL D PE TG K --- 500
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 549 npynakp QY sike E L G -- WRFNNQY L M A D L EL F NYAIT N RLLSTNVYL N NQ sisst INA G NQTA RGV DFMI SG HPYHHVS 626
Cdd:COG4773 501 ------- QY ---- E A G vk GELFDGR L N A T L AV F DITQK N VATTDPDNP N FY ----- VQV G EVRS RGV ELEL SG ELTPGLN 564
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 627 PFVSVE Y LN A ttdsniattgtlng K TVG D LLPTK G NTAVQS P HVH AS AGL TY D -- N G T --- FFAN G S V S YV SSQ Y STFM N 701
Cdd:COG4773 565 LIAGYT Y TD A -------------- K ITK D ADALE G KRLTNV P RHT AS LWT TY R fp S G A lkg LGLG G G V R YV GER Y GDAA N 630
650 660 670
....*....|....*....|....*....|....*.
gi 2520615286 702 DQKM P G Y VTDNLAIG Y RFK sfgam K TPKF QLN FS NL 737
Cdd:COG4773 631 TFTL P S Y TLVDAGAR Y DLG ----- K NWTL QLN VN NL 661
TonB_dep_Rec
pfam00593 TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
288-737
2.93e-18
TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
Pssm-ID: 395474 [Multi-domain]
Cd Length: 475
Bit Score: 88.67
E-value: 2.93e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 288 RVRTFN Y SSSY D QANPS D YGMLN G NMWDQVFVTLPLHVQLPS R FS L DFKPY Y VYNG G YTYNGS L FN G SATPATV G PNGNA 367
Cdd:pfam00593 18 GYDYSR Y TDGL D LGLTL D GYGND G GYLGDRPLYYGRDYSDTD R KR L SLGYD Y DLGD G LSWLST L RL G LRYSSLD G DYTSN 97
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 368 I SG NLP A AS Y Y S VY R PHAGAV ak L NY D IDVHDR L TFGYWFDYQDNQVDNR Y SA L SSTGKQ P FPY A SSAGIYV S GSRY mpy 447
Cdd:pfam00593 98 S SG LSG A GD Y L S DD R LYGLYG -- L DG D LELSLD L SHDLLLGVELRTAGLD Y RR L DDDAYD P YDP A NPSSSSY S DTTT --- 172
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 448 kgdsgw KIHS L FIE D DT KL l N D K L RINA G FKIAMINRWSGNYASTAPRIQSNQVVPL P QAAIS Y NIDSHNMV Y VNAEGD F 527
Cdd:pfam00593 173 ------ DSYG L YLQ D NI KL - T D R L TLTL G LRYDHYSTDGDDGNGGGDNFSRSYSAFS P RLGLV Y KPTDNLSL Y ASYSRG F 245
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 528 R M P DP G S L - G QVFDAQT G TYV G NPYNA KP QY S IKE ELG WRFNNQY L MAD L E LF NYA I T N RLL S - TNVYLNNQSISSTI N A 605
Cdd:pfam00593 246 R A P SL G E L y G SGSGGGG G AVA G GNPDL KP ET S DNY ELG LKYDDGR L SLS L A LF YID I K N LIT S d PDGPGLGGTVYTYT N V 325
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 606 G NQTA RGV DFMI SG HPYHHVSPFVSVE Y LN A TT D SNIAT T gtlngktvgdllptk GN TAVQS P HVH A SA GLTYD -- N G TF 683
Cdd:pfam00593 326 G KARI RGV ELEL SG RLWGLGLSGGGYT Y TD A DD D ADADD T --------------- GN PLPNV P RHT A NL GLTYD fp L G GW 390
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*..
gi 2520615286 684 F A NGSVS YV S S QYSTFMNDQ --- K M PGY VTDN L AI GYR FK sfgam K TPKFQ L NFS NL 737
Cdd:pfam00593 391 G A RLGAR YV G S GERRYGDAA ntf K T PGY TLVD L SA GYR LN ----- K NLTLR L GVN NL 442
BtuB
COG4206 Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism];
55-340
4.11e-08
Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism];
Pssm-ID: 443355 [Multi-domain]
Cd Length: 276
Bit Score: 55.26
E-value: 4.11e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 55 IS VT SS R RA lnggggm MRHETASH S IQTVTRQYID m Q S P A STAL D MVKNL P S V V VS TVDSS G I l GGQ I NS R S L TDSDMGI 134
Cdd:COG4206 1 VV VT AT R LE ------- QSKSDLTG S VTVIDAEELE - R S G A TSLA D ALRRV P G V Q VS SSGGP G S - AAS I SI R G L GSNQTLV 71
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 135 L L DGVP VATA --- YYLNQNVDTENLAA I S V TP G S A AI d L PVTS A AA G IM N SE T FQPSDK F G G LMDF SYG TNNLS R EFLRV 211
Cdd:COG4206 72 L I DGVP LNDP slg GVDLSLIPPDDIER I E V LK G A A SA - L YGSD A IG G VI N IT T KKGKKG F K G SVSA SYG SFGTR R LSASL 150
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 212 e SG AI G HSGIRTYT S FSHT --- HARTW D GPGTNERRHLDVG A TKDFQD G SFVN L FV S WNHQF tmaplnp TAQQFFDKKSR 288
Cdd:COG4206 151 - SG GA G KFSYSLSA S YRRS dgy RYNDP D LRNNDGYENTSLN A RLGYKL G DNGS L SL S GGYSD ------- SERGYPGAVGS 222
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|..
gi 2520615286 289 V R TFNY S S S YDQANPSDYGM L NGNMWDQVFVTLPLHVQLPSRFSL D FKPYYV 340
Cdd:COG4206 223 D R NLRL S L S LEYKLSDGWSL L LLAYYYYDRDYEDGGGDSAGTSNT D GARAGL 274
Plug
pfam07715 TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently ...
74-167
3.94e-07
TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently folding subunit of the TonB-dependent receptors. It acts as the channel gate, blocking the pore until the channel is bound by ligand. At this point it under goes conformational changes opens the channel.
Pssm-ID: 462243 [Multi-domain]
Cd Length: 107
Bit Score: 49.19
E-value: 3.94e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2520615286 74 ETASH S IQT VT RQY I DM Q s P A STAL D MVKNL P S V V VS TVDSS G il G GQ I NS R SLTDSDMGI L L DGVP VATAYYLN --- QN 150
Cdd:pfam07715 3 RDTPG S VSV VT AED I ED Q - G A TNLA D ALRGV P G V S VS SGGGG G -- G SS I SI R GFGSNRVLV L V DGVP LNSGGGGS vdl NS 79
90
....*....|....*..
gi 2520615286 151 V D T E NLAAIS V TP G S A A 167
Cdd:pfam07715 80 I D P E DIERVE V LK G P A S 96
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
