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Concise Results
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Full Results
CMY-2 family class C beta-lactamase [Citrobacter sp. Cb009]
Protein Classification
beta-lactamase ( domain architecture ID 10013775 )
beta-lactamase, belonging to the class C family, catalyzes the hydrolysis of beta-lactams such as cephalosporins
List of domain hits
Name
Accession
Description
Interval
E-value
ampC
PRK11289 beta-lactamase/D-alanine carboxypeptidase; Provisional
1-381
0e+00
beta-lactamase/D-alanine carboxypeptidase; Provisional
Pssm-ID: 236894
Cd Length: 384
Bit Score: 642.71
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524296444 1 MM KKSICC ALLLTAS F S T FAAA K T E QQ IA DIV N RTITPLM Q EQ A IPGMAVA I IY Q GKPYYF TW G K AD I A NNR PVTQ Q TLF 80
Cdd:PRK11289 4 MM LLLLLA ALLLTAS A S A FAAA A T P QQ LK DIV D RTITPLM E EQ D IPGMAVA V IY N GKPYYF NY G V AD K A TGQ PVTQ D TLF 83
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524296444 81 ELGSVSKTF NGV L G G D A I ARGE IK LSDP VTQ Y W PEL T G KQWQ GI S LLHLATYTAGGLPLQVPD D V T D K A A LLR FY Q N WQP 160
Cdd:PRK11289 84 ELGSVSKTF TAT L A G Y A Q ARGE LS LSDP ASK Y L PEL K G SPFD GI T LLHLATYTAGGLPLQVPD E V K D D A Q LLR YF Q A WQP 163
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524296444 161 QW APG AK RLY A N S SIGLFG A LA V K PS G MSY E EA M SK R VLH PL K L A HT W I T VP QS E QK DYA W GY - R EGKPV H V S PG Q LDAE 239
Cdd:PRK11289 164 AY APG TQ RLY S N P SIGLFG Y LA A K AM G QPF E QL M EQ R LFP PL G L T HT Y I N VP EA E MA DYA Q GY n K EGKPV R V N PG V LDAE 243
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524296444 240 AYGVKS SVI DM T R W VQAN MDASQV q EK TLQQ G I E L A Q SR Y W R I GDM Y QGLGWEM LNW PV KA D SIIS G SDS K V AL AAL P AV 319
Cdd:PRK11289 244 AYGVKS TAA DM L R F VQAN LGPQDL - DP TLQQ A I Q L T Q TG Y F R V GDM T QGLGWEM YPY PV SL D TLLA G NSN K M AL EPQ P VT 322
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2524296444 320 EVN PP A P A V K A S W VH KTGST G GFG S YVAFVP E K N LGIVMLANK S YPNP V R IE AA WR IL EK L Q 381
Cdd:PRK11289 323 AIT PP Q P P V R A V W IN KTGST N GFG A YVAFVP A K R LGIVMLANK N YPNP A R VK AA YQ IL NA L A 384
Name
Accession
Description
Interval
E-value
ampC
PRK11289 beta-lactamase/D-alanine carboxypeptidase; Provisional
1-381
0e+00
beta-lactamase/D-alanine carboxypeptidase; Provisional
Pssm-ID: 236894
Cd Length: 384
Bit Score: 642.71
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524296444 1 MM KKSICC ALLLTAS F S T FAAA K T E QQ IA DIV N RTITPLM Q EQ A IPGMAVA I IY Q GKPYYF TW G K AD I A NNR PVTQ Q TLF 80
Cdd:PRK11289 4 MM LLLLLA ALLLTAS A S A FAAA A T P QQ LK DIV D RTITPLM E EQ D IPGMAVA V IY N GKPYYF NY G V AD K A TGQ PVTQ D TLF 83
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524296444 81 ELGSVSKTF NGV L G G D A I ARGE IK LSDP VTQ Y W PEL T G KQWQ GI S LLHLATYTAGGLPLQVPD D V T D K A A LLR FY Q N WQP 160
Cdd:PRK11289 84 ELGSVSKTF TAT L A G Y A Q ARGE LS LSDP ASK Y L PEL K G SPFD GI T LLHLATYTAGGLPLQVPD E V K D D A Q LLR YF Q A WQP 163
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524296444 161 QW APG AK RLY A N S SIGLFG A LA V K PS G MSY E EA M SK R VLH PL K L A HT W I T VP QS E QK DYA W GY - R EGKPV H V S PG Q LDAE 239
Cdd:PRK11289 164 AY APG TQ RLY S N P SIGLFG Y LA A K AM G QPF E QL M EQ R LFP PL G L T HT Y I N VP EA E MA DYA Q GY n K EGKPV R V N PG V LDAE 243
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524296444 240 AYGVKS SVI DM T R W VQAN MDASQV q EK TLQQ G I E L A Q SR Y W R I GDM Y QGLGWEM LNW PV KA D SIIS G SDS K V AL AAL P AV 319
Cdd:PRK11289 244 AYGVKS TAA DM L R F VQAN LGPQDL - DP TLQQ A I Q L T Q TG Y F R V GDM T QGLGWEM YPY PV SL D TLLA G NSN K M AL EPQ P VT 322
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2524296444 320 EVN PP A P A V K A S W VH KTGST G GFG S YVAFVP E K N LGIVMLANK S YPNP V R IE AA WR IL EK L Q 381
Cdd:PRK11289 323 AIT PP Q P P V R A V W IN KTGST N GFG A YVAFVP A K R LGIVMLANK N YPNP A R VK AA YQ IL NA L A 384
ampC_Kaer
NF041662 CMY2-MIR-ACT-EC family cephalosporin-hydrolyzing class C beta-lactamase; This narrowly defined ...
1-381
0e+00
CMY2-MIR-ACT-EC family cephalosporin-hydrolyzing class C beta-lactamase; This narrowly defined subfamily of AmpC class C beta-lactamases covers chromosomal ly encoded proteins apparently restricted to and universal in Klebsiella (previously Enterobacter) aerogenes. Strains encoding this enzyme tend to be resistant to penicillins and first and second generation cephalosporins.
Pssm-ID: 469544
Cd Length: 381
Bit Score: 630.28
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524296444 1 MMKKS ICCA LLL T ASFSTFAA AK T EQ Q IADI VN R TITPLM Q EQAIPGMAVA I IY Q GKPYYFTWG K AD I A NN RPVT Q QTLF 80
Cdd:NF041662 1 MMKKS LTGV LLL G ASFSTFAA PQ T AE Q LREL VN Q TITPLM K EQAIPGMAVA V IY H GKPYYFTWG Q AD V A GQ RPVT R QTLF 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524296444 81 ELGSVSKTF N GVLGGDA I ARGEIKLSDP VTQ YWP E LTG K QWQGISLLHLATYTAGGLPLQVPD D VTD K AALLR F YQNWQP 160
Cdd:NF041662 81 ELGSVSKTF T GVLGGDA V ARGEIKLSDP AQK YWP Q LTG Q QWQGISLLHLATYTAGGLPLQVPD E VTD E AALLR Y YQNWQP 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524296444 161 QWAPG A KRLYAN S SIGLFGALAVKPSGMS Y E E AMS K RVL H PLKL A HTWI T VP QSEQ KDYAWGYR E GK P VHVSPGQLDAEA 240
Cdd:NF041662 161 QWAPG S KRLYAN A SIGLFGALAVKPSGMS F E Q AMS Q RVL Q PLKL S HTWI N VP PAQS KDYAWGYR D GK A VHVSPGQLDAEA 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524296444 241 YGVKSS VI DM TR WV Q ANM DASQ VQ E K T L Q QGI E LAQSRYWR I G D MYQGLGWEMLNWPV K A DSI I S GSD S KVALAA L P AVE 320
Cdd:NF041662 241 YGVKSS IE DM AH WV L ANM NREA VQ D K N L R QGI Q LAQSRYWR A G E MYQGLGWEMLNWPV S A EVL I N GSD N KVALAA T P VTA 320
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2524296444 321 VNPPAP A VKASWVHKTGSTGGFGSYVAF V P EKN LGIVMLANKSYPNP V R IE AA WR ILE K LQ 381
Cdd:NF041662 321 VNPPAP P VKASWVHKTGSTGGFGSYVAF I P QQD LGIVMLANKSYPNP E R VK AA YH ILE A LQ 381
ampC_Ecan
NF041666 CMY2-MIR-ACT-EC family cephalosporin-hydrolyzing class C beta-lactamase; This HMM identifies a ...
1-381
0e+00
CMY2-MIR-ACT-EC family cephalosporin-hydrolyzing class C beta-lactamase; This HMM identifies a small subset of chromosomal class C beta-lactamases (AmpC) typical of Enterobacter cancerogenus.
Pssm-ID: 469548
Cd Length: 381
Bit Score: 596.37
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524296444 1 M M KK SIC CALLL TA S F S TF A AAKT E QQI A DI V N RT I TPLM QE Q A IPGMAVA I IYQG K P Y YFT W GKAD I A N N R PVT Q QTLF 80
Cdd:NF041666 1 M K KK LVF CALLL GV S C S AL A SSLS E KEL A KV V K RT V TPLM KA Q S IPGMAVA V IYQG Q P H YFT F GKAD V A A N I PVT P QTLF 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524296444 81 ELGSVSKTF N GVLGGDAIARGEI K L S DPVT Q YWPELTGKQWQGI S LL H LATYTAGGLPLQVPD D VTD K AALL R FYQ N WQP 160
Cdd:NF041666 81 ELGSVSKTF T GVLGGDAIARGEI S L N DPVT R YWPELTGKQWQGI R LL D LATYTAGGLPLQVPD N VTD P AALL N FYQ T WQP 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524296444 161 QW A PG AK RLYANSSIGLFGALAVKPSGM SY E E AM SK RVL H PLKL A HTWI TV P Q SE QKD YAWGYR E GK P VHVSPG Q LD A EA 240
Cdd:NF041666 161 QW K PG TT RLYANSSIGLFGALAVKPSGM GF E Q AM TT RVL K PLKL D HTWI QI P K SE EQH YAWGYR D GK A VHVSPG M LD G EA 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524296444 241 YGVKS SVI DM TR WV QA NM DASQ VQ EKT L Q QGI E LAQSRYWR I G D MYQGLGWEMLNWPV KADS II S GSD S K V ALAALPA V E 320
Cdd:NF041666 241 YGVKS NAE DM AS WV MV NM ALER VQ ATS L K QGI A LAQSRYWR V G S MYQGLGWEMLNWPV DGKT II D GSD N K I ALAALPA R E 320
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2524296444 321 VNPPAP A VKASWVHKTGSTGGFGSYVAF V PEK N LGIVMLANKSYPNP V R I EAA WR IL EK LQ 381
Cdd:NF041666 321 VNPPAP P VKASWVHKTGSTGGFGSYVAF I PEK Q LGIVMLANKSYPNP A R V EAA YQ IL NA LQ 381
Beta-lactamase
pfam00144 Beta-lactamase; This family appears to be distantly related to pfam00905 and PF00768 ...
32-381
1.13e-98
Beta-lactamase; This family appears to be distantly related to pfam00905 and PF00768 D-alanyl-D-alanine carboxypeptidase.
Pssm-ID: 395092 [Multi-domain]
Cd Length: 327
Bit Score: 296.34
E-value: 1.13e-98
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524296444 32 VN R T I TP LM QEQA IPG M AVA IIYQ GK PYYFTW - G K AD IANN RPVT QQ TLF ELG SV S KTF NGVLGGDAIA RG EIK L S DPV T 110
Cdd:pfam00144 1 LD R L I RE LM AQGG IPG V AVA VTRD GK VVVDRG g G V AD LEGG RPVT AD TLF RIA SV T KTF TAAAVLQLVE RG KLD L D DPV S 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524296444 111 Q Y W PE LT G KQWQ GI S L LH L A T Y T A G GL PL QV PDD VTDK AA ---- L L R FYQNWQ P Q W A PG AKRL Y A N SSI GL F G A L AVKPS 186
Cdd:pfam00144 81 K Y L PE FA G PGKG GI T L RD L L T H T S G LP PL FA PDD LEEA AA daae L V R ALAALP P V W P PG TRWG Y S N TAY GL L G E L LERVT 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524296444 187 G M SYEE AMSK R V L H PL KLAH T WIT VP QSEQKDY A W GY - R EG K PV H V S PG Q L D A E AY - G V KS SVI D MT R WVQ A NMDASQVQ 264
Cdd:pfam00144 161 G Q SYEE LLGD R I L R PL GMTD T ELG VP EPGDPRD A A GY t G EG P PV R V P PG P L P A G AY g G L KS TAR D LA R FLL A LLGGLLLS 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524296444 265 EKT L Q Q GIELAQSRYWRI G DMYQ GLG wem L N W PVK adsiisgsdskvalaalpavevnp PAPAVKASWVHK tgs TGG F G S 344
Cdd:pfam00144 241 AAA L A Q LTDWLRGGTTGV G GIRA GLG --- L G W VLA ------------------------ DKTGAGPGLFGH --- TGG Y G T 290
330 340 350
....*....|....*....|....*....|....*..
gi 2524296444 345 Y V A FV P EKN L GI V M L A N KSY PNP VRI E A A WR I LEKLQ 381
Cdd:pfam00144 291 Y L A VD P DIG L VV V V L S N RLG PNP DAA E D A RL I ALAAA 327
AmpC
COG1680 CubicO group peptidase, beta-lactamase class C family [Defense mechanisms];
16-377
5.34e-73
CubicO group peptidase, beta-lactamase class C family [Defense mechanisms];
Pssm-ID: 441286 [Multi-domain]
Cd Length: 355
Bit Score: 231.50
E-value: 5.34e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524296444 16 F STF A A A KTEQQIADIVNRTITPLMQ E QA IPG M AVA IIYQ GK PY Y F - TW G K AD IANN RPVT QQ TLF ELG SV S K T F NGVLG 94
Cdd:COG1680 3 F AAA A P A AGLSADLAALDAALDAALA E GG IPG A AVA VVRD GK VV Y E k AY G V AD LETG RPVT PD TLF RIA SV T K S F TATAV 82
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524296444 95 GDAIAR G EIK L S DPV TQ Y W PE LTGK -- QWQG I SLL HL A T Y T A G g LP LQV PD -------- DVTDKAA LL RFYQNWQPQWA P 164
Cdd:COG1680 83 LQLVEE G KLD L D DPV SK Y L PE FKLP dd AKRD I TVR HL L T H T S G - LP DYE PD pydaadva RPYTPDD LL ARLAALPLLFE P 161
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524296444 165 G AKRL Y A N SSIG L F G ALAVKPS G MSY E EAMSK R VLH PL KLAH T WITV P QS E QKDY A W GY REGKP VH VS P GQ L D A E -- A Y G 242
Cdd:COG1680 162 G TRFS Y S N LGYD L L G EIIERVT G QPL E DYLRE R IFE PL GMTD T GFGL P DA E AARL A P GY EADGE VH DA P AW L G A V ag A G G 241
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524296444 243 VK S SVI D MT R WV QA NMDASQVQE K T L -- QQGIELAQSRYWRI GD -- MYQ GLGW EMLNWP vkadsiis GS D skvalaalpa 318
Cdd:COG1680 242 LF S TAR D LA R FG QA LLNGGEWDG K R L ls PETLAEMTTPQVPS GD ag GGY GLGW WLNDDG -------- GS G ---------- 303
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*....
gi 2524296444 319 vevnppapavkas WVHKT G S T G GF GSYVAFV PE KN LG I V M L A N KSY P NPVRIE A AWRI L 377
Cdd:COG1680 304 ------------- SFGHG G A T P GF STFLWVD PE RG LG V V V L T N RDD P GAGDRA A LLEA L 349
Name
Accession
Description
Interval
E-value
ampC
PRK11289 beta-lactamase/D-alanine carboxypeptidase; Provisional
1-381
0e+00
beta-lactamase/D-alanine carboxypeptidase; Provisional
Pssm-ID: 236894
Cd Length: 384
Bit Score: 642.71
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524296444 1 MM KKSICC ALLLTAS F S T FAAA K T E QQ IA DIV N RTITPLM Q EQ A IPGMAVA I IY Q GKPYYF TW G K AD I A NNR PVTQ Q TLF 80
Cdd:PRK11289 4 MM LLLLLA ALLLTAS A S A FAAA A T P QQ LK DIV D RTITPLM E EQ D IPGMAVA V IY N GKPYYF NY G V AD K A TGQ PVTQ D TLF 83
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524296444 81 ELGSVSKTF NGV L G G D A I ARGE IK LSDP VTQ Y W PEL T G KQWQ GI S LLHLATYTAGGLPLQVPD D V T D K A A LLR FY Q N WQP 160
Cdd:PRK11289 84 ELGSVSKTF TAT L A G Y A Q ARGE LS LSDP ASK Y L PEL K G SPFD GI T LLHLATYTAGGLPLQVPD E V K D D A Q LLR YF Q A WQP 163
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524296444 161 QW APG AK RLY A N S SIGLFG A LA V K PS G MSY E EA M SK R VLH PL K L A HT W I T VP QS E QK DYA W GY - R EGKPV H V S PG Q LDAE 239
Cdd:PRK11289 164 AY APG TQ RLY S N P SIGLFG Y LA A K AM G QPF E QL M EQ R LFP PL G L T HT Y I N VP EA E MA DYA Q GY n K EGKPV R V N PG V LDAE 243
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524296444 240 AYGVKS SVI DM T R W VQAN MDASQV q EK TLQQ G I E L A Q SR Y W R I GDM Y QGLGWEM LNW PV KA D SIIS G SDS K V AL AAL P AV 319
Cdd:PRK11289 244 AYGVKS TAA DM L R F VQAN LGPQDL - DP TLQQ A I Q L T Q TG Y F R V GDM T QGLGWEM YPY PV SL D TLLA G NSN K M AL EPQ P VT 322
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2524296444 320 EVN PP A P A V K A S W VH KTGST G GFG S YVAFVP E K N LGIVMLANK S YPNP V R IE AA WR IL EK L Q 381
Cdd:PRK11289 323 AIT PP Q P P V R A V W IN KTGST N GFG A YVAFVP A K R LGIVMLANK N YPNP A R VK AA YQ IL NA L A 384
ampC_Kaer
NF041662 CMY2-MIR-ACT-EC family cephalosporin-hydrolyzing class C beta-lactamase; This narrowly defined ...
1-381
0e+00
CMY2-MIR-ACT-EC family cephalosporin-hydrolyzing class C beta-lactamase; This narrowly defined subfamily of AmpC class C beta-lactamases covers chromosomal ly encoded proteins apparently restricted to and universal in Klebsiella (previously Enterobacter) aerogenes. Strains encoding this enzyme tend to be resistant to penicillins and first and second generation cephalosporins.
Pssm-ID: 469544
Cd Length: 381
Bit Score: 630.28
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524296444 1 MMKKS ICCA LLL T ASFSTFAA AK T EQ Q IADI VN R TITPLM Q EQAIPGMAVA I IY Q GKPYYFTWG K AD I A NN RPVT Q QTLF 80
Cdd:NF041662 1 MMKKS LTGV LLL G ASFSTFAA PQ T AE Q LREL VN Q TITPLM K EQAIPGMAVA V IY H GKPYYFTWG Q AD V A GQ RPVT R QTLF 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524296444 81 ELGSVSKTF N GVLGGDA I ARGEIKLSDP VTQ YWP E LTG K QWQGISLLHLATYTAGGLPLQVPD D VTD K AALLR F YQNWQP 160
Cdd:NF041662 81 ELGSVSKTF T GVLGGDA V ARGEIKLSDP AQK YWP Q LTG Q QWQGISLLHLATYTAGGLPLQVPD E VTD E AALLR Y YQNWQP 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524296444 161 QWAPG A KRLYAN S SIGLFGALAVKPSGMS Y E E AMS K RVL H PLKL A HTWI T VP QSEQ KDYAWGYR E GK P VHVSPGQLDAEA 240
Cdd:NF041662 161 QWAPG S KRLYAN A SIGLFGALAVKPSGMS F E Q AMS Q RVL Q PLKL S HTWI N VP PAQS KDYAWGYR D GK A VHVSPGQLDAEA 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524296444 241 YGVKSS VI DM TR WV Q ANM DASQ VQ E K T L Q QGI E LAQSRYWR I G D MYQGLGWEMLNWPV K A DSI I S GSD S KVALAA L P AVE 320
Cdd:NF041662 241 YGVKSS IE DM AH WV L ANM NREA VQ D K N L R QGI Q LAQSRYWR A G E MYQGLGWEMLNWPV S A EVL I N GSD N KVALAA T P VTA 320
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2524296444 321 VNPPAP A VKASWVHKTGSTGGFGSYVAF V P EKN LGIVMLANKSYPNP V R IE AA WR ILE K LQ 381
Cdd:NF041662 321 VNPPAP P VKASWVHKTGSTGGFGSYVAF I P QQD LGIVMLANKSYPNP E R VK AA YH ILE A LQ 381
ampC_Ecan
NF041666 CMY2-MIR-ACT-EC family cephalosporin-hydrolyzing class C beta-lactamase; This HMM identifies a ...
1-381
0e+00
CMY2-MIR-ACT-EC family cephalosporin-hydrolyzing class C beta-lactamase; This HMM identifies a small subset of chromosomal class C beta-lactamases (AmpC) typical of Enterobacter cancerogenus.
Pssm-ID: 469548
Cd Length: 381
Bit Score: 596.37
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524296444 1 M M KK SIC CALLL TA S F S TF A AAKT E QQI A DI V N RT I TPLM QE Q A IPGMAVA I IYQG K P Y YFT W GKAD I A N N R PVT Q QTLF 80
Cdd:NF041666 1 M K KK LVF CALLL GV S C S AL A SSLS E KEL A KV V K RT V TPLM KA Q S IPGMAVA V IYQG Q P H YFT F GKAD V A A N I PVT P QTLF 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524296444 81 ELGSVSKTF N GVLGGDAIARGEI K L S DPVT Q YWPELTGKQWQGI S LL H LATYTAGGLPLQVPD D VTD K AALL R FYQ N WQP 160
Cdd:NF041666 81 ELGSVSKTF T GVLGGDAIARGEI S L N DPVT R YWPELTGKQWQGI R LL D LATYTAGGLPLQVPD N VTD P AALL N FYQ T WQP 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524296444 161 QW A PG AK RLYANSSIGLFGALAVKPSGM SY E E AM SK RVL H PLKL A HTWI TV P Q SE QKD YAWGYR E GK P VHVSPG Q LD A EA 240
Cdd:NF041666 161 QW K PG TT RLYANSSIGLFGALAVKPSGM GF E Q AM TT RVL K PLKL D HTWI QI P K SE EQH YAWGYR D GK A VHVSPG M LD G EA 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524296444 241 YGVKS SVI DM TR WV QA NM DASQ VQ EKT L Q QGI E LAQSRYWR I G D MYQGLGWEMLNWPV KADS II S GSD S K V ALAALPA V E 320
Cdd:NF041666 241 YGVKS NAE DM AS WV MV NM ALER VQ ATS L K QGI A LAQSRYWR V G S MYQGLGWEMLNWPV DGKT II D GSD N K I ALAALPA R E 320
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2524296444 321 VNPPAP A VKASWVHKTGSTGGFGSYVAF V PEK N LGIVMLANKSYPNP V R I EAA WR IL EK LQ 381
Cdd:NF041666 321 VNPPAP P VKASWVHKTGSTGGFGSYVAF I PEK Q LGIVMLANKSYPNP A R V EAA YQ IL NA LQ 381
Beta-lactamase
pfam00144 Beta-lactamase; This family appears to be distantly related to pfam00905 and PF00768 ...
32-381
1.13e-98
Beta-lactamase; This family appears to be distantly related to pfam00905 and PF00768 D-alanyl-D-alanine carboxypeptidase.
Pssm-ID: 395092 [Multi-domain]
Cd Length: 327
Bit Score: 296.34
E-value: 1.13e-98
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524296444 32 VN R T I TP LM QEQA IPG M AVA IIYQ GK PYYFTW - G K AD IANN RPVT QQ TLF ELG SV S KTF NGVLGGDAIA RG EIK L S DPV T 110
Cdd:pfam00144 1 LD R L I RE LM AQGG IPG V AVA VTRD GK VVVDRG g G V AD LEGG RPVT AD TLF RIA SV T KTF TAAAVLQLVE RG KLD L D DPV S 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524296444 111 Q Y W PE LT G KQWQ GI S L LH L A T Y T A G GL PL QV PDD VTDK AA ---- L L R FYQNWQ P Q W A PG AKRL Y A N SSI GL F G A L AVKPS 186
Cdd:pfam00144 81 K Y L PE FA G PGKG GI T L RD L L T H T S G LP PL FA PDD LEEA AA daae L V R ALAALP P V W P PG TRWG Y S N TAY GL L G E L LERVT 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524296444 187 G M SYEE AMSK R V L H PL KLAH T WIT VP QSEQKDY A W GY - R EG K PV H V S PG Q L D A E AY - G V KS SVI D MT R WVQ A NMDASQVQ 264
Cdd:pfam00144 161 G Q SYEE LLGD R I L R PL GMTD T ELG VP EPGDPRD A A GY t G EG P PV R V P PG P L P A G AY g G L KS TAR D LA R FLL A LLGGLLLS 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524296444 265 EKT L Q Q GIELAQSRYWRI G DMYQ GLG wem L N W PVK adsiisgsdskvalaalpavevnp PAPAVKASWVHK tgs TGG F G S 344
Cdd:pfam00144 241 AAA L A Q LTDWLRGGTTGV G GIRA GLG --- L G W VLA ------------------------ DKTGAGPGLFGH --- TGG Y G T 290
330 340 350
....*....|....*....|....*....|....*..
gi 2524296444 345 Y V A FV P EKN L GI V M L A N KSY PNP VRI E A A WR I LEKLQ 381
Cdd:pfam00144 291 Y L A VD P DIG L VV V V L S N RLG PNP DAA E D A RL I ALAAA 327
AmpC
COG1680 CubicO group peptidase, beta-lactamase class C family [Defense mechanisms];
16-377
5.34e-73
CubicO group peptidase, beta-lactamase class C family [Defense mechanisms];
Pssm-ID: 441286 [Multi-domain]
Cd Length: 355
Bit Score: 231.50
E-value: 5.34e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524296444 16 F STF A A A KTEQQIADIVNRTITPLMQ E QA IPG M AVA IIYQ GK PY Y F - TW G K AD IANN RPVT QQ TLF ELG SV S K T F NGVLG 94
Cdd:COG1680 3 F AAA A P A AGLSADLAALDAALDAALA E GG IPG A AVA VVRD GK VV Y E k AY G V AD LETG RPVT PD TLF RIA SV T K S F TATAV 82
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524296444 95 GDAIAR G EIK L S DPV TQ Y W PE LTGK -- QWQG I SLL HL A T Y T A G g LP LQV PD -------- DVTDKAA LL RFYQNWQPQWA P 164
Cdd:COG1680 83 LQLVEE G KLD L D DPV SK Y L PE FKLP dd AKRD I TVR HL L T H T S G - LP DYE PD pydaadva RPYTPDD LL ARLAALPLLFE P 161
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524296444 165 G AKRL Y A N SSIG L F G ALAVKPS G MSY E EAMSK R VLH PL KLAH T WITV P QS E QKDY A W GY REGKP VH VS P GQ L D A E -- A Y G 242
Cdd:COG1680 162 G TRFS Y S N LGYD L L G EIIERVT G QPL E DYLRE R IFE PL GMTD T GFGL P DA E AARL A P GY EADGE VH DA P AW L G A V ag A G G 241
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524296444 243 VK S SVI D MT R WV QA NMDASQVQE K T L -- QQGIELAQSRYWRI GD -- MYQ GLGW EMLNWP vkadsiis GS D skvalaalpa 318
Cdd:COG1680 242 LF S TAR D LA R FG QA LLNGGEWDG K R L ls PETLAEMTTPQVPS GD ag GGY GLGW WLNDDG -------- GS G ---------- 303
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*....
gi 2524296444 319 vevnppapavkas WVHKT G S T G GF GSYVAFV PE KN LG I V M L A N KSY P NPVRIE A AWRI L 377
Cdd:COG1680 304 ------------- SFGHG G A T P GF STFLWVD PE RG LG V V V L T N RDD P GAGDRA A LLEA L 349
PRK10662
PRK10662 beta-lactam binding protein AmpH; Provisional
1-363
1.77e-29
beta-lactam binding protein AmpH; Provisional
Pssm-ID: 236732 [Multi-domain]
Cd Length: 378
Bit Score: 117.06
E-value: 1.77e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524296444 1 M MKKSICC A L L LT A SFSTFA AA KT --- EQQIA DIV N R TITPLMQEQAIP GMA VAI I YQGKPYYFTW G KADIA NN RPVTQQ 77
Cdd:PRK10662 1 M KRSLLFS A A L CA A ALTSAH AA QP aad PLLAS DIV D R YAEHIFYGSGAT GMA LVV I DGNQRVFRSY G ETRPG NN VRPQLD 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524296444 78 T L FELG S VS K TFNGVLGGDAIAR G EI KL S DP VTQ Y W P --- ELTGKQW Q G I S LL H LAT Y T AG g LP LQV P DDVTDKAALL -- 152
Cdd:PRK10662 81 S L IRIA S IT K LMTSEVLVKLADD G TV KL T DP LSK Y A P pga RVPTYNG Q P I T LL N LAT H T SA - LP REQ P GGAAHRPVFV wp 159
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524296444 153 RFY Q N W Q ------ PQW APG AKRL Y A N SSIG L FG - ALA v K PS G MS Y EEAMSKRVLH PL KLAH T WI T VPQSEQKDYAW G YRE 225
Cdd:PRK10662 160 TRE Q R W K wlstak LKA APG TQAA Y S N LAFD L LA d ALA - K AA G KP Y TQLLREKITR PL GMKD T TF T PSPDQCARLMV G EKG 238
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524296444 226 GK P VHVSPG ql DAEAY GV K S SVI DM T RW V Q ANMD a S QVQEKTL Q qg IELA Q SRYWRIGDMYQGL G WEM lnw P V KAD SIIS 305
Cdd:PRK10662 239 AS P CNNTLA -- AIGSG GV Y S TPG DM M RW M Q QFLS - S DNYQRSQ Q -- ADRM Q TLIYQRAQLTSVI G MDV --- P G KAD ALGL 310
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*...
gi 2524296444 306 G S dsk V AL A ALPAV evnppa P AV kasw VH KTG ST GGF GS Y V A FV P EK N L G IVMLANK S 363
Cdd:PRK10662 311 G W --- V YM A PKDGR ------ P GI ---- IQ KTG GG GGF IT Y M A MI P QR N I G VFVVVTR S 355
PRK13128
PRK13128 D-aminopeptidase; Reviewed
46-354
7.79e-07
D-aminopeptidase; Reviewed
Pssm-ID: 171868 [Multi-domain]
Cd Length: 518
Bit Score: 51.01
E-value: 7.79e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524296444 46 PG M AVA IIYQ G KPYY - FT WG K AD I A NNRPV T QQ T LFELG SVSK T F N - G VL g G D A I ARG E I k L SDPVTQ Y WPELTGKQ wqg 123
Cdd:PRK13128 23 PG G AVA VVKD G EVVL r HA WG F AD L A RRKAM T PE T RMPIC SVSK Q F T c A VL - L D C I GEP E M - L DAALAA Y LDQFEDPR --- 97
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524296444 124 ISLLH L A ------------ T YTA G GL P LQV -- PD DVTDKAAL L R fyqnw QPQW APG AKRL Y A N SSIGLFGA L AVKPS G M S 189
Cdd:PRK13128 98 PAVRD L C nnqsglrdywal T VLC G AA P EGI fl PD QAQNLLRR L K ----- TTHF APG THYS Y C N GNFRILAD L IEQHT G R S 172
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524296444 190 YEEAMSK R VLH P LKL a H T WITV P QSEQK D YAW GY r EG KP V H vsp G Q L D A EA ------- Y G VKS S VI DM TR W V Q A n M D ASQ 262
Cdd:PRK13128 173 LADLLAE R IFA P AGM - K T AELI P DTALF D ECT GY - EG DT V R --- G F L P A IN rihwlgd A G ICA S LD DM IA W E Q F - I D RTR 246
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524296444 263 VQ E KT L QQGIELA Q S ------------- RYWRI G ---- DMYQ G L -- GW EMLN W PV k AD SII S -------- G SD S KV AL AA 315
Cdd:PRK13128 247 DD E NG L YRRLSVP Q T fadgapapygfgl KFEET G gkrl TGHG G A lr GW RCQR W HC - AD ERL S tivmfnfe G NA S DA AL KM 325
330 340 350
....*....|....*....|....*....|....*....
gi 2524296444 316 LP A VEVN PPA PA V K A S wvhkt GST G G FGS YVA fv PE KN L 354
Cdd:PRK13128 326 MN A ALGI PPA KP V R A Q ----- ANP G W FGS WLN -- PE TG L 357
PRK03642
PRK03642 putative periplasmic esterase; Provisional
2-207
3.09e-04
putative periplasmic esterase; Provisional
Pssm-ID: 179620 [Multi-domain]
Cd Length: 432
Bit Score: 42.47
E-value: 3.09e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524296444 2 MK KSICCAL LL TA S F S TF AA ------- A KT E QQIADIVNRTITPLMQE Q A I ---- PG MAVA II YQGKPY Y F - T WG K A --- 66
Cdd:PRK03642 1 MK RTLLYTS LL AF S C S AS AA kypvlte A SP E KAGFNSEKLNQMDRWIS Q Q I dagy PG VNLL II KDNQIV Y R k A WG Y A kky 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524296444 67 -- DIANNR PV -- T QQ T LFE L G S VS K TF -- N GV L G g DAIAR G EIKLS D PVTQ Y W P E -------- LT GK - QWQG I S LLH lat 131
Cdd:PRK03642 81 dg STLLAH PV ka T TN T MYD L A S NT K MY at N FA L Q - KLVSE G KLDVN D LISK Y I P G fkdspgdk IK GK n TLRI I D LLH --- 156
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524296444 132 y TAG G L P -- L Q V P DDVT ------- DK AAL L RFYQNWQPQWA PG A K RL Y ANSSIG L F G ALAVKPS G MSYEEAMSKRVLH PL 202
Cdd:PRK03642 157 - HSA G F P ad P Q Y P NKAV agalysq DK STT L EMIKKTPLEYQ PG S K HI Y SDVDYM L L G FIVESIT G QPLDRYVEESIYR PL 235
....*
gi 2524296444 203 K L A HT 207
Cdd:PRK03642 236 G L T HT 240
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
