|
Name |
Accession |
Description |
Interval |
E-value |
| PykF |
COG0469 |
Pyruvate kinase [Carbohydrate transport and metabolism]; Pyruvate kinase is part of the ... |
3-468 |
0e+00 |
|
Pyruvate kinase [Carbohydrate transport and metabolism]; Pyruvate kinase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 440237 [Multi-domain] Cd Length: 471 Bit Score: 726.44 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 3 RHRNVKIVATLGPSSNDYNMIRALFEAGADVFRLNMSHGSHDEIRERHTIIRQIEKDLDRPIAILADLQGPKLRCGVFSG 82
Cdd:COG0469 1 MMRRTKIVATLGPASDSPEVLRKLIEAGMDVARLNFSHGDHEEHRERIELIREAAKELGRPVAILLDLQGPKIRTGKFKE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 83 DSEELVVGEPFRFDLDPAEGNARRVCLPHKEIFQALRPGATLLVNDGKIRLKVEECGADFAECTVMVGGTISNRKGVNVP 162
Cdd:COG0469 81 GPVELKKGDTFTLTTDDVEGDAERVSVTYPELPEDVKPGDRILLDDGKIELRVEEVEGDEVVCEVVNGGVLSSRKGVNLP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 163 DVVLPLAALSPKDRKDLEFVCELGVDWIALSFVQRPEDVLEARTLVR---GRAAILSKIEKPAAVTAFAEILEVSDGIMV 239
Cdd:COG0469 161 GVGLSLPALTEKDREDLKFALELGVDFIALSFVRSAEDVLEARELLEeagGRAPIIAKIEKPEAVENLDEIIEASDGIMV 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 240 ARGDLGVELPVQNVSPIQKRLVRACRAAAKPVIVATQMLESMIESPVPTRAEVSDVATAIYEGADAVMLSAESAAGAYPI 319
Cdd:COG0469 241 ARGDLGVEIPLEEVPLIQKRIIRKARRAGKPVITATQMLESMIENPRPTRAEVSDVANAVLDGTDAVMLSGETAVGKYPV 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 320 EAVTTMNNVAEEVEHDPTYREVIEASRGASRPGVAGGIVAAAREIAETADIKVICCFTHSGTTAALTARERPRVPILALT 399
Cdd:COG0469 321 EAVETMARIAEEAEKSLDYRRILDRLRDEPERTITDAIARAAVELAEDLGAKAIVAFTESGSTARRISRYRPKVPILALT 400
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2525123055 400 PFAATARRLCLTWGIQCFFTGEVDRFKMAVVSAARAAREGGYATEQDQIVVTAGVPFNEPGTTNILRVA 468
Cdd:COG0469 401 PNERTARRLALVWGVYPVLVDDVESTDEMIEEAVEALLEEGLVKPGDLVVITAGVPVGVPGTTNTLKVH 469
|
|
| PRK06247 |
PRK06247 |
pyruvate kinase; Provisional |
1-468 |
0e+00 |
|
pyruvate kinase; Provisional
Pssm-ID: 180487 [Multi-domain] Cd Length: 476 Bit Score: 693.98 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 1 MRRHRNVKIVATLGPSSNDYNMIRALFEAGADVFRLNMSHGSHDEIRERHTIIRQIEKDLDRPIAILADLQGPKLRCGVF 80
Cdd:PRK06247 1 MKRNRRVKILATLGPASSSEDMIRKLVEAGADVFRLNFSHGDHDDHRELYKRIREVEDETGRPIGILADLQGPKLRLGRF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 81 SGDSEELVVGEPFRFDLDPAEGNARRVCLPHKEIFQALRPGATLLVNDGKIRLKVEECGADFAECTVMVGGTISNRKGVN 160
Cdd:PRK06247 81 ADGKVQLANGQTFRLDVDDAPGDHDRVSLPHPEIAAALKPGDRLLVDDGKVRLVVEACDGDDVVCRVVEGGPVSDRKGVS 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 161 VPDVVLPLAALSPKDRKDLEFVCELGVDWIALSFVQRPEDVLEARTLVRGRAAILSKIEKPAAVTAFAEILEVSDGIMVA 240
Cdd:PRK06247 161 LPGTVLSVSALTEKDRADLEFALELGVDWVALSFVQRPEDVEEVRKIIGGRVPVMAKIEKPQAIDRLEAIVEASDAIMVA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 241 RGDLGVELPVQNVSPIQKRLVRACRAAAKPVIVATQMLESMIESPVPTRAEVSDVATAIYEGADAVMLSAESAAGAYPIE 320
Cdd:PRK06247 241 RGDLGVEVPLEQVPLIQKRIIRAARRAGKPVVVATQMLESMIENPVPTRAEVSDVATAVLDGADAVMLSAETASGKYPVE 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 321 AVTTMNNVAEEVEHDPTYREVIEASRGASRPGVAGGIVAAAREIAETADIKVICCFTHSGTTAALTARERPRVPILALTP 400
Cdd:PRK06247 321 AVRTMARIIRQVERDPTYPPLIHAQRPQPEATKRDAISYAARDIAERLDLAALVAYTSSGDTALRAARERPPLPILALTP 400
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2525123055 401 FAATARRLCLTWGIQCFFTGEVDRFKMAVVSAARAAREGGYATEQDQIVVTAGVPFNEPGTTNILRVA 468
Cdd:PRK06247 401 NPETARRLALTWGVHCVVVDDARDTDDMVRRADRIALAEGFYKRGDRVVIVAGVPPGTPGSTNMLRIA 468
|
|
| pyruv_kin |
TIGR01064 |
pyruvate kinase; This enzyme is a homotetramer. Some forms are active only in the presence of ... |
5-467 |
7.49e-179 |
|
pyruvate kinase; This enzyme is a homotetramer. Some forms are active only in the presence of fructose-1,6-bisphosphate or similar phosphorylated sugars. [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 273424 [Multi-domain] Cd Length: 472 Bit Score: 509.51 E-value: 7.49e-179
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 5 RNVKIVATLGPSSNDYNMIRALFEAGADVFRLNMSHGSHDEIRERHTIIRQIEKDLDRPIAILADLQGPKLRCGVFSGDS 84
Cdd:TIGR01064 1 RRTKIVCTIGPATNSPEMLKKLLDAGMNVARLNFSHGSHEEHGKRIENVREAAEKLGRPVAILLDTKGPEIRTGEIKGGE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 85 EELVVGEPFRFDLDPA--EGNARRVCLPHKEIFQALRPGATLLVNDGKIRLKVEECGADFAECTVMVGGTISNRKGVNVP 162
Cdd:TIGR01064 81 VKLKKGDKVIITTDDIkgEGDEEKVYVDYKGLTKDVVEGDKILVDDGKISLVVVSVEGDKVICEVLNGGTLKSKKGVNLP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 163 DVVLPLAALSPKDRKDLEFVCELGVDWIALSFVQRPEDVLEARTLVR----GRAAILSKIEKPAAVTAFAEILEVSDGIM 238
Cdd:TIGR01064 161 GADVDLPALSEKDKKDLKFGVEQGVDMVAASFVRTAEDVLEVREVLGekgaKDVKIIAKIENQEGVDNIDEIAEASDGIM 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 239 VARGDLGVELPVQNVSPIQKRLVRACRAAAKPVIVATQMLESMIESPVPTRAEVSDVATAIYEGADAVMLSAESAAGAYP 318
Cdd:TIGR01064 241 VARGDLGVEIPAEEVPIAQKKMIRKCNRAGKPVITATQMLDSMIKNPRPTRAEVSDVANAVLDGTDAVMLSGETAKGKYP 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 319 IEAVTTMNNVAEEVEHDPTYREVI-EASRGASRPG-VAGGIVAAAREIAETADIKVICCFTHSGTTAALTARERPRVPIL 396
Cdd:TIGR01064 321 VEAVQMMAKIAKEAEKALAYLTNFnDRKNSDPKPStITEAIALSAVEAAEKLDAKAIVVLTESGRTARLLSKYRPNAPII 400
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2525123055 397 ALTPFAATARRLCLTWGIQCFFTGE-VDRFKMAVVSAARAAREGGYATEQDQIVVTAGVPFNEPGTTNILRV 467
Cdd:TIGR01064 401 AVTPNERVARQLALYWGVFPFLVDEePSDTDARVNKALELLKEKGIVKKGDLVVVIQGGPIGGEGGTNTIRV 472
|
|
| Pyruvate_Kinase |
cd00288 |
Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of ... |
4-467 |
2.09e-158 |
|
Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low affinity T state. PK exists as several different isozymes, depending on organism and tissue type. In mammals, there are four PK isozymes: R, found in red blood cells, L, found in liver, M1, found in skeletal muscle, and M2, found in kidney, adipose tissue, and lung. PK forms a homotetramer, with each subunit containing three domains. The T state to R state transition of PK is more complex than in most allosteric enzymes, involving a concerted rotation of all 3 domains of each monomer in the homotetramer.
Pssm-ID: 238178 [Multi-domain] Cd Length: 480 Bit Score: 457.93 E-value: 2.09e-158
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 4 HRNVKIVATLGPSSNDYNMIRALFEAGADVFRLNMSHGSHDEIRERHTIIRQIEKDLDRPIAILADLQGPKLRCGVFSGD 83
Cdd:cd00288 1 LRRTKIVCTIGPATDSVENLKKLIKAGMNVARMNFSHGSHEYHQSRIDNVREAAEKTGGPVAIALDTKGPEIRTGLFKGG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 84 SE-ELVVGEPFRFDLDPA--EGNARRVCLPHKEIFQALRPGATLLVNDGKIRLKVEECGAD-FAECTVMVGGTISNRKGV 159
Cdd:cd00288 81 KDiSLKAGDKFLVTTDPAakKGTKEKIYVDYKNLTKDVSPGNTILVDDGLLSLKVLSKDDDkTLVCEVLNGGVLGSRKGV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 160 NVPDVVLPLAALSPKDRKDLEFVCELGVDWIALSFVQRPEDVLEARTLVRG---RAAILSKIEKPAAVTAFAEILEVSDG 236
Cdd:cd00288 161 NLPGTDVDLPALSEKDKADLRFGVEQGVDMIFASFVRKASDVLEIREVLGEkgkDIKIIAKIENQEGVNNFDEILEASDG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 237 IMVARGDLGVELPVQNVSPIQKRLVRACRAAAKPVIVATQMLESMIESPVPTRAEVSDVATAIYEGADAVMLSAESAAGA 316
Cdd:cd00288 241 IMVARGDLGVEIPAEEVFLAQKMLIAKCNLAGKPVITATQMLESMIYNPRPTRAEVSDVANAVLDGTDCVMLSGETAKGK 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 317 YPIEAVTTMNNVAEEVEHDPTYREVI-EASRGASRPG-VAGGIVAAAREIAETADIKVICCFTHSGTTAALTARERPRVP 394
Cdd:cd00288 321 YPVEAVKAMARICLEAEKALSHRVLFnEMRRLTPRPTsTTEAVAMSAVRAAFELGAKAIVVLTTSGRTARLVSKYRPNAP 400
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2525123055 395 ILALTPFAATARRLCLTWGIQCFFTGEV------DRFKMaVVSAARAAREGGYATEQDQIVVTAGVPFnEPGTTNILRV 467
Cdd:cd00288 401 IIAVTRNEQTARQLHLYRGVYPVLFEEPkpgwqeDTDAR-LKAAVNVAKEKGLLKKGDLVVVVQGWPV-GSGSTNTMRI 477
|
|
| PK |
pfam00224 |
Pyruvate kinase, barrel domain; This domain of the is actually a small beta-barrel domain ... |
5-341 |
8.58e-127 |
|
Pyruvate kinase, barrel domain; This domain of the is actually a small beta-barrel domain nested within a larger TIM barrel. The active site is found in a cleft between the two domains.
Pssm-ID: 395168 [Multi-domain] Cd Length: 348 Bit Score: 372.47 E-value: 8.58e-127
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 5 RNVKIVATLGPSSNDYNMIRALFEAGADVFRLNMSHGSHDEIRERHTIIRQIEKDLDRPIAILADLQGPKLRCGVFSGDS 84
Cdd:pfam00224 2 RRTKIVCTIGPASNSVENLEKLIEAGANVARMNFSHGSHEYHQSRIDNVREAEEKTGGTVAIALDTKGPEIRTGNTKDGK 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 85 E--ELVVGEPFRFDLDPA---EGNARRVCLPHKEIFQALRPGATLLVNDGKIRLKVEECGADFA-ECTVMVGGTISNRKG 158
Cdd:pfam00224 82 KdiELKAGDEMIVSTDAKykgACDDEMIYVDYKNIVKDVSVGGTILVDDGLLSLKVLSKDDDKTlVVEVLNGGVIGSRKG 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 159 VNVPDVVLPLAALSPKDRKDLEFVCELGVDWIALSFVQRPEDVLEARTLVRG---RAAILSKIEKPAAVTAFAEILEVSD 235
Cdd:pfam00224 162 VNLPGTDVDLPALSEKDKADLRFGVKNGVDMIFASFVRKASDVLEIREVLGEagkNIQIIAKIENQEGVNNFDEILEATD 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 236 GIMVARGDLGVELPVQNVSPIQKRLVRACRAAAKPVIVATQMLESMIESPVPTRAEVSDVATAIYEGADAVMLSAESAAG 315
Cdd:pfam00224 242 GIMVARGDLGIEIPAEEVFLAQKMLIAKCNLAGKPVITATQMLESMIYNPRPTRAEVSDVANAVLDGTDCVMLSGETAKG 321
|
330 340
....*....|....*....|....*.
gi 2525123055 316 AYPIEAVTTMNNVAEEVEHDPTYREV 341
Cdd:pfam00224 322 NYPVEAVRMMHEICLEAEKALPHRNL 347
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PykF |
COG0469 |
Pyruvate kinase [Carbohydrate transport and metabolism]; Pyruvate kinase is part of the ... |
3-468 |
0e+00 |
|
Pyruvate kinase [Carbohydrate transport and metabolism]; Pyruvate kinase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 440237 [Multi-domain] Cd Length: 471 Bit Score: 726.44 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 3 RHRNVKIVATLGPSSNDYNMIRALFEAGADVFRLNMSHGSHDEIRERHTIIRQIEKDLDRPIAILADLQGPKLRCGVFSG 82
Cdd:COG0469 1 MMRRTKIVATLGPASDSPEVLRKLIEAGMDVARLNFSHGDHEEHRERIELIREAAKELGRPVAILLDLQGPKIRTGKFKE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 83 DSEELVVGEPFRFDLDPAEGNARRVCLPHKEIFQALRPGATLLVNDGKIRLKVEECGADFAECTVMVGGTISNRKGVNVP 162
Cdd:COG0469 81 GPVELKKGDTFTLTTDDVEGDAERVSVTYPELPEDVKPGDRILLDDGKIELRVEEVEGDEVVCEVVNGGVLSSRKGVNLP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 163 DVVLPLAALSPKDRKDLEFVCELGVDWIALSFVQRPEDVLEARTLVR---GRAAILSKIEKPAAVTAFAEILEVSDGIMV 239
Cdd:COG0469 161 GVGLSLPALTEKDREDLKFALELGVDFIALSFVRSAEDVLEARELLEeagGRAPIIAKIEKPEAVENLDEIIEASDGIMV 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 240 ARGDLGVELPVQNVSPIQKRLVRACRAAAKPVIVATQMLESMIESPVPTRAEVSDVATAIYEGADAVMLSAESAAGAYPI 319
Cdd:COG0469 241 ARGDLGVEIPLEEVPLIQKRIIRKARRAGKPVITATQMLESMIENPRPTRAEVSDVANAVLDGTDAVMLSGETAVGKYPV 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 320 EAVTTMNNVAEEVEHDPTYREVIEASRGASRPGVAGGIVAAAREIAETADIKVICCFTHSGTTAALTARERPRVPILALT 399
Cdd:COG0469 321 EAVETMARIAEEAEKSLDYRRILDRLRDEPERTITDAIARAAVELAEDLGAKAIVAFTESGSTARRISRYRPKVPILALT 400
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2525123055 400 PFAATARRLCLTWGIQCFFTGEVDRFKMAVVSAARAAREGGYATEQDQIVVTAGVPFNEPGTTNILRVA 468
Cdd:COG0469 401 PNERTARRLALVWGVYPVLVDDVESTDEMIEEAVEALLEEGLVKPGDLVVITAGVPVGVPGTTNTLKVH 469
|
|
| PRK06247 |
PRK06247 |
pyruvate kinase; Provisional |
1-468 |
0e+00 |
|
pyruvate kinase; Provisional
Pssm-ID: 180487 [Multi-domain] Cd Length: 476 Bit Score: 693.98 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 1 MRRHRNVKIVATLGPSSNDYNMIRALFEAGADVFRLNMSHGSHDEIRERHTIIRQIEKDLDRPIAILADLQGPKLRCGVF 80
Cdd:PRK06247 1 MKRNRRVKILATLGPASSSEDMIRKLVEAGADVFRLNFSHGDHDDHRELYKRIREVEDETGRPIGILADLQGPKLRLGRF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 81 SGDSEELVVGEPFRFDLDPAEGNARRVCLPHKEIFQALRPGATLLVNDGKIRLKVEECGADFAECTVMVGGTISNRKGVN 160
Cdd:PRK06247 81 ADGKVQLANGQTFRLDVDDAPGDHDRVSLPHPEIAAALKPGDRLLVDDGKVRLVVEACDGDDVVCRVVEGGPVSDRKGVS 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 161 VPDVVLPLAALSPKDRKDLEFVCELGVDWIALSFVQRPEDVLEARTLVRGRAAILSKIEKPAAVTAFAEILEVSDGIMVA 240
Cdd:PRK06247 161 LPGTVLSVSALTEKDRADLEFALELGVDWVALSFVQRPEDVEEVRKIIGGRVPVMAKIEKPQAIDRLEAIVEASDAIMVA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 241 RGDLGVELPVQNVSPIQKRLVRACRAAAKPVIVATQMLESMIESPVPTRAEVSDVATAIYEGADAVMLSAESAAGAYPIE 320
Cdd:PRK06247 241 RGDLGVEVPLEQVPLIQKRIIRAARRAGKPVVVATQMLESMIENPVPTRAEVSDVATAVLDGADAVMLSAETASGKYPVE 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 321 AVTTMNNVAEEVEHDPTYREVIEASRGASRPGVAGGIVAAAREIAETADIKVICCFTHSGTTAALTARERPRVPILALTP 400
Cdd:PRK06247 321 AVRTMARIIRQVERDPTYPPLIHAQRPQPEATKRDAISYAARDIAERLDLAALVAYTSSGDTALRAARERPPLPILALTP 400
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2525123055 401 FAATARRLCLTWGIQCFFTGEVDRFKMAVVSAARAAREGGYATEQDQIVVTAGVPFNEPGTTNILRVA 468
Cdd:PRK06247 401 NPETARRLALTWGVHCVVVDDARDTDDMVRRADRIALAEGFYKRGDRVVIVAGVPPGTPGSTNMLRIA 468
|
|
| PRK05826 |
PRK05826 |
pyruvate kinase; Provisional |
1-460 |
0e+00 |
|
pyruvate kinase; Provisional
Pssm-ID: 235619 [Multi-domain] Cd Length: 465 Bit Score: 530.49 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 1 MRRHRnVKIVATLGPSSNDYNMIRALFEAGADVFRLNMSHGSHDEIRERHTIIRQIEKDLDRPIAILADLQGPKLRCGVF 80
Cdd:PRK05826 1 RMLRR-TKIVATLGPASDSPENLEKLIEAGVNVVRLNFSHGSHEEHGKRAALVREIAAKLGRPVAILLDLKGPKIRVGKF 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 81 SGDSEELVVGEPFRFDLDPA-EGNARRVCLPHKEIFQALRPGATLLVNDGKIRLKVEECGADFAECTVMVGGTISNRKGV 159
Cdd:PRK05826 80 KEGKITLKTGDKFTLDTDQKeEGDKERVGVDYKGLPKDVKPGDILLLDDGKLQLKVVEVDGDEVETEVKNGGPLSNNKGI 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 160 NVPDVVLPLAALSPKDRKDLEFVCELGVDWIALSFVQRPEDVLEARTLVR----GRAAILSKIEKPAAVTAFAEILEVSD 235
Cdd:PRK05826 160 NIPGGGLSLPALTEKDKADIKFAAEQGVDYIAVSFVRSAEDVEEARRLLReagcPHAKIIAKIERAEAVDNIDEIIEASD 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 236 GIMVARGDLGVELPVQNVSPIQKRLVRACRAAAKPVIVATQMLESMIESPVPTRAEVSDVATAIYEGADAVMLSAESAAG 315
Cdd:PRK05826 240 GIMVARGDLGVEIPDEEVPGLQKKIIRKAREAGKPVITATQMLESMIENPRPTRAEVSDVANAVLDGTDAVMLSGETAAG 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 316 AYPIEAVTTMNNVAEEVEHDPT---YREVIEASRGASRPGVAGGIVAAAREIaetADIKVICCFTHSGTTAALTARERPR 392
Cdd:PRK05826 320 KYPVEAVEAMARICKGAEKEFSinlSKHRLDRQFDRIDEAIAMSAMYAANHL---KGVKAIVALTESGRTARLISRFRPG 396
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2525123055 393 VPILALTPFAATARRLCLTWGIQCFFTGEVDRFKMAVVSAARAAREGGYATEQDQIVVTAGVPFNEPG 460
Cdd:PRK05826 397 APIFAVTRDEKTQRRLALYRGVYPVLFDSAADTDDAAEEALRLLLEKGLVESGDLVVVTSGDPMGTAG 464
|
|
| pyruv_kin |
TIGR01064 |
pyruvate kinase; This enzyme is a homotetramer. Some forms are active only in the presence of ... |
5-467 |
7.49e-179 |
|
pyruvate kinase; This enzyme is a homotetramer. Some forms are active only in the presence of fructose-1,6-bisphosphate or similar phosphorylated sugars. [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 273424 [Multi-domain] Cd Length: 472 Bit Score: 509.51 E-value: 7.49e-179
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 5 RNVKIVATLGPSSNDYNMIRALFEAGADVFRLNMSHGSHDEIRERHTIIRQIEKDLDRPIAILADLQGPKLRCGVFSGDS 84
Cdd:TIGR01064 1 RRTKIVCTIGPATNSPEMLKKLLDAGMNVARLNFSHGSHEEHGKRIENVREAAEKLGRPVAILLDTKGPEIRTGEIKGGE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 85 EELVVGEPFRFDLDPA--EGNARRVCLPHKEIFQALRPGATLLVNDGKIRLKVEECGADFAECTVMVGGTISNRKGVNVP 162
Cdd:TIGR01064 81 VKLKKGDKVIITTDDIkgEGDEEKVYVDYKGLTKDVVEGDKILVDDGKISLVVVSVEGDKVICEVLNGGTLKSKKGVNLP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 163 DVVLPLAALSPKDRKDLEFVCELGVDWIALSFVQRPEDVLEARTLVR----GRAAILSKIEKPAAVTAFAEILEVSDGIM 238
Cdd:TIGR01064 161 GADVDLPALSEKDKKDLKFGVEQGVDMVAASFVRTAEDVLEVREVLGekgaKDVKIIAKIENQEGVDNIDEIAEASDGIM 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 239 VARGDLGVELPVQNVSPIQKRLVRACRAAAKPVIVATQMLESMIESPVPTRAEVSDVATAIYEGADAVMLSAESAAGAYP 318
Cdd:TIGR01064 241 VARGDLGVEIPAEEVPIAQKKMIRKCNRAGKPVITATQMLDSMIKNPRPTRAEVSDVANAVLDGTDAVMLSGETAKGKYP 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 319 IEAVTTMNNVAEEVEHDPTYREVI-EASRGASRPG-VAGGIVAAAREIAETADIKVICCFTHSGTTAALTARERPRVPIL 396
Cdd:TIGR01064 321 VEAVQMMAKIAKEAEKALAYLTNFnDRKNSDPKPStITEAIALSAVEAAEKLDAKAIVVLTESGRTARLLSKYRPNAPII 400
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2525123055 397 ALTPFAATARRLCLTWGIQCFFTGE-VDRFKMAVVSAARAAREGGYATEQDQIVVTAGVPFNEPGTTNILRV 467
Cdd:TIGR01064 401 AVTPNERVARQLALYWGVFPFLVDEePSDTDARVNKALELLKEKGIVKKGDLVVVIQGGPIGGEGGTNTIRV 472
|
|
| PRK06354 |
PRK06354 |
pyruvate kinase; Provisional |
5-467 |
1.28e-164 |
|
pyruvate kinase; Provisional
Pssm-ID: 235784 [Multi-domain] Cd Length: 590 Bit Score: 477.50 E-value: 1.28e-164
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 5 RNVKIVATLGPSSNDYNMIRALFEAGADVFRLNMSHGSHDEIRERHTIIRQIEKDLDRPIAILADLQGPKLRCGVFSGDS 84
Cdd:PRK06354 8 RRTKIVATIGPASESPEKLRQLIEAGATTARLNFSHGDHEEHGARIKNIREASKKLGKTVGILQDLQGPKIRLGRFEDGP 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 85 EELVVGEPFRFDLDPAEGNARRVCLPHKEIFQALRPGATLLVNDGKIRLKVEECGADFAE--CTVMVGGTISNRKGVNVP 162
Cdd:PRK06354 88 IELKTGDEFILTSREVLGTQEKFSVTYDGLADEVPVGSRILLDDGLIELEVEEVDKADGElhCKVLVGGVLSNKKGVNFP 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 163 DVVLPLAALSPKDRKDLEFVCELGVDWIALSFVQRPEDVLEARTLVRGRAA----ILSKIEKPAAVTAFAEILEVSDGIM 238
Cdd:PRK06354 168 GVSLSLPAITEKDREDLIFGLEQGVDWIALSFVRNPSDVLEIRELIEEHNGkhipIIAKIEKQEAIDNIDAILELCDGLM 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 239 VARGDLGVELPVQNVSPIQKRLVRACRAAAKPVIVATQMLESMIESPVPTRAEVSDVATAIYEGADAVMLSAESAAGAYP 318
Cdd:PRK06354 248 VARGDLGVEIPAEEVPLLQKRLIKKANRLGKPVITATQMLDSMQRNPRPTRAEASDVANAILDGTDAVMLSNETAAGDYP 327
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 319 IEAVTTMNNVAEEVEHDPTYREvIEASRGASRPGVAGGIVAAAREIAETADIKVICCFTHSGTTAALTARERPRVPILAL 398
Cdd:PRK06354 328 VEAVQTMATIAVRIEKDLPYRD-ILSKRPEFTTTITNAISQAVSHIALQLDAAAIVTLTKSGATARNVSKYRPKTPILAV 406
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2525123055 399 TPFAATARRLCLTWGIQCFFTGEVDRFKMAVVSAARAAREGGYATEQDQIVVTAGVPFNEPGTTNILRV 467
Cdd:PRK06354 407 TPNESVARRLQLVWGVTPLLVLDAPSTDETFDAAINVAQESGLLKQGDLVVITAGTLVGESGSTDLMKV 475
|
|
| Pyruvate_Kinase |
cd00288 |
Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of ... |
4-467 |
2.09e-158 |
|
Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low affinity T state. PK exists as several different isozymes, depending on organism and tissue type. In mammals, there are four PK isozymes: R, found in red blood cells, L, found in liver, M1, found in skeletal muscle, and M2, found in kidney, adipose tissue, and lung. PK forms a homotetramer, with each subunit containing three domains. The T state to R state transition of PK is more complex than in most allosteric enzymes, involving a concerted rotation of all 3 domains of each monomer in the homotetramer.
Pssm-ID: 238178 [Multi-domain] Cd Length: 480 Bit Score: 457.93 E-value: 2.09e-158
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 4 HRNVKIVATLGPSSNDYNMIRALFEAGADVFRLNMSHGSHDEIRERHTIIRQIEKDLDRPIAILADLQGPKLRCGVFSGD 83
Cdd:cd00288 1 LRRTKIVCTIGPATDSVENLKKLIKAGMNVARMNFSHGSHEYHQSRIDNVREAAEKTGGPVAIALDTKGPEIRTGLFKGG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 84 SE-ELVVGEPFRFDLDPA--EGNARRVCLPHKEIFQALRPGATLLVNDGKIRLKVEECGAD-FAECTVMVGGTISNRKGV 159
Cdd:cd00288 81 KDiSLKAGDKFLVTTDPAakKGTKEKIYVDYKNLTKDVSPGNTILVDDGLLSLKVLSKDDDkTLVCEVLNGGVLGSRKGV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 160 NVPDVVLPLAALSPKDRKDLEFVCELGVDWIALSFVQRPEDVLEARTLVRG---RAAILSKIEKPAAVTAFAEILEVSDG 236
Cdd:cd00288 161 NLPGTDVDLPALSEKDKADLRFGVEQGVDMIFASFVRKASDVLEIREVLGEkgkDIKIIAKIENQEGVNNFDEILEASDG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 237 IMVARGDLGVELPVQNVSPIQKRLVRACRAAAKPVIVATQMLESMIESPVPTRAEVSDVATAIYEGADAVMLSAESAAGA 316
Cdd:cd00288 241 IMVARGDLGVEIPAEEVFLAQKMLIAKCNLAGKPVITATQMLESMIYNPRPTRAEVSDVANAVLDGTDCVMLSGETAKGK 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 317 YPIEAVTTMNNVAEEVEHDPTYREVI-EASRGASRPG-VAGGIVAAAREIAETADIKVICCFTHSGTTAALTARERPRVP 394
Cdd:cd00288 321 YPVEAVKAMARICLEAEKALSHRVLFnEMRRLTPRPTsTTEAVAMSAVRAAFELGAKAIVVLTTSGRTARLVSKYRPNAP 400
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2525123055 395 ILALTPFAATARRLCLTWGIQCFFTGEV------DRFKMaVVSAARAAREGGYATEQDQIVVTAGVPFnEPGTTNILRV 467
Cdd:cd00288 401 IIAVTRNEQTARQLHLYRGVYPVLFEEPkpgwqeDTDAR-LKAAVNVAKEKGLLKKGDLVVVVQGWPV-GSGSTNTMRI 477
|
|
| PK |
pfam00224 |
Pyruvate kinase, barrel domain; This domain of the is actually a small beta-barrel domain ... |
5-341 |
8.58e-127 |
|
Pyruvate kinase, barrel domain; This domain of the is actually a small beta-barrel domain nested within a larger TIM barrel. The active site is found in a cleft between the two domains.
Pssm-ID: 395168 [Multi-domain] Cd Length: 348 Bit Score: 372.47 E-value: 8.58e-127
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 5 RNVKIVATLGPSSNDYNMIRALFEAGADVFRLNMSHGSHDEIRERHTIIRQIEKDLDRPIAILADLQGPKLRCGVFSGDS 84
Cdd:pfam00224 2 RRTKIVCTIGPASNSVENLEKLIEAGANVARMNFSHGSHEYHQSRIDNVREAEEKTGGTVAIALDTKGPEIRTGNTKDGK 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 85 E--ELVVGEPFRFDLDPA---EGNARRVCLPHKEIFQALRPGATLLVNDGKIRLKVEECGADFA-ECTVMVGGTISNRKG 158
Cdd:pfam00224 82 KdiELKAGDEMIVSTDAKykgACDDEMIYVDYKNIVKDVSVGGTILVDDGLLSLKVLSKDDDKTlVVEVLNGGVIGSRKG 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 159 VNVPDVVLPLAALSPKDRKDLEFVCELGVDWIALSFVQRPEDVLEARTLVRG---RAAILSKIEKPAAVTAFAEILEVSD 235
Cdd:pfam00224 162 VNLPGTDVDLPALSEKDKADLRFGVKNGVDMIFASFVRKASDVLEIREVLGEagkNIQIIAKIENQEGVNNFDEILEATD 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 236 GIMVARGDLGVELPVQNVSPIQKRLVRACRAAAKPVIVATQMLESMIESPVPTRAEVSDVATAIYEGADAVMLSAESAAG 315
Cdd:pfam00224 242 GIMVARGDLGIEIPAEEVFLAQKMLIAKCNLAGKPVITATQMLESMIYNPRPTRAEVSDVANAVLDGTDCVMLSGETAKG 321
|
330 340
....*....|....*....|....*.
gi 2525123055 316 AYPIEAVTTMNNVAEEVEHDPTYREV 341
Cdd:pfam00224 322 NYPVEAVRMMHEICLEAEKALPHRNL 347
|
|
| PRK09206 |
PRK09206 |
pyruvate kinase PykF; |
8-467 |
1.88e-125 |
|
pyruvate kinase PykF;
Pssm-ID: 181699 [Multi-domain] Cd Length: 470 Bit Score: 373.24 E-value: 1.88e-125
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 8 KIVATLGPSSNDYNMIRALFEAGADVFRLNMSHGSHDEIRERHTIIRQIEKDLDRPIAILADLQGPKLRCGVF-SGDSEE 86
Cdd:PRK09206 5 KIVCTIGPKTESEEMLTKLLDAGMNVMRLNFSHGDYAEHGQRIKNLRNVMSKTGKKAAILLDTKGPEIRTMKLeGGNDVS 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 87 LVVGEPFRFDLDPA-EGNARRVCLPHKEIFQALRPGATLLVNDGKIRLKVEECGADFAECTVMVGGTISNRKGVNVPDVV 165
Cdd:PRK09206 85 LKAGQTFTFTTDKSvVGNKERVAVTYEGFTADLSVGNTVLVDDGLIGMEVTAITGNEVICKVLNNGDLGENKGVNLPGVS 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 166 LPLAALSPKDRKDLEFVCELGVDWIALSFVQRPEDVLEARTLVRG----RAAILSKIEKPAAVTAFAEILEVSDGIMVAR 241
Cdd:PRK09206 165 IALPALAEKDKQDLIFGCEQGVDFVAASFIRKRSDVLEIREHLKAhggeNIQIISKIENQEGLNNFDEILEASDGIMVAR 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 242 GDLGVELPVQNVSPIQKRLVRACRAAAKPVIVATQMLESMIESPVPTRAEVSDVATAIYEGADAVMLSAESAAGAYPIEA 321
Cdd:PRK09206 245 GDLGVEIPVEEVIFAQKMMIEKCNRARKVVITATQMLDSMIKNPRPTRAEAGDVANAILDGTDAVMLSGESAKGKYPLEA 324
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 322 VTTMNNVAEEVehDPTYREVIEASRGASRPGVAGGIVAAAREIAETADIKVICCFTHSGTTAALTARERPRVPILALTPF 401
Cdd:PRK09206 325 VSIMATICERT--DRVMNSRLESNNDNRKLRITEAVCRGAVETAEKLDAPLIVVATQGGKSARSVRKYFPDATILALTTN 402
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2525123055 402 AATARRLCLTWGIQCFFTGEVDRFKMAVVSAARAAREGGYATEQDQIVVTAGVPFnEPGTTNILRV 467
Cdd:PRK09206 403 EKTARQLVLSKGVVPQLVKEIASTDDFYRLGKELALQSGLAQKGDVVVMVSGALV-PSGTTNTASV 467
|
|
| PTZ00066 |
PTZ00066 |
pyruvate kinase; Provisional |
3-471 |
2.97e-103 |
|
pyruvate kinase; Provisional
Pssm-ID: 173361 [Multi-domain] Cd Length: 513 Bit Score: 317.86 E-value: 2.97e-103
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 3 RHRNVKIVATLGPSSNDYNMIRALFEAGADVFRLNMSHGSHDEIRERHTIIRQIEKDldRP---IAILADLQGPKLRCGV 79
Cdd:PTZ00066 36 RQKKTHIVCTMGPACKNVETLVKLIDAGMNICRFNFSHGDHESHKKTLNNVREAAKA--RPnanLGILLDTKGPEIRTGF 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 80 FSGDSE-ELVVGEPFRFDLD-PAEGNARRVCLPHKEIFQALRPGATLLVNDGKIRLKVEECGADFAECTVMVGGTISNRK 157
Cdd:PTZ00066 114 LKNHKPiTLKEGQTLKITTDyTFLGDETCISCSYKKLPQSVKVGNIILIADGSLSCKVLEVHDDYIITKVLNNATIGERK 193
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 158 GVNVPDVVLPLAALSPKDRKD-LEFVCELGVDWIALSFVQRPEDVLEARTLV--RGR-AAILSKIEKPAAVTAFAEILEV 233
Cdd:PTZ00066 194 NMNLPGVKVELPVIGEKDKNDiLNFAIPMGCDFIALSFVQSADDVRLCRQLLgeRGRhIKIIPKIENIEGLINFDEILAE 273
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 234 SDGIMVARGDLGVELPVQNVSPIQKRLVRACRAAAKPVIVATQMLESMIESPVPTRAEVSDVATAIYEGADAVMLSAESA 313
Cdd:PTZ00066 274 SDGIMVARGDLGMEIPPEKVFLAQKMMISKCNVAGKPVITATQMLESMIKNPRPTRAESTDVANAVLDGTDCVMLSGETA 353
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 314 AGAYPIEAVTTMNNVAEEVEHDPTYREVIEASRGASRPGVA--GGIVAAAREIAETADIKVICCFTHSGTTAALTARERP 391
Cdd:PTZ00066 354 NGKFPVEAVNIMAKICFEAETCIDYRVLYHAIHLAVPTPVSvqEAVARSAVETAEDINAKLIIALTETGNTARLISKYRP 433
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 392 RVPILALTPFAATARRLCLTWGIQCFFTGEVDRFKMAVVSAARAAREGGYATEQDQIVVTAGVPFNEPGTTNILRVAPCE 471
Cdd:PTZ00066 434 SCTILALSASPSVVKSLSVARGVTTYVVNSFQGTDVVIRNAIALAKERGLVESGDSAIAVHGVKEEVAGSSNLMKVVKIP 513
|
|
| PRK06739 |
PRK06739 |
pyruvate kinase; Validated |
10-334 |
1.61e-97 |
|
pyruvate kinase; Validated
Pssm-ID: 180676 [Multi-domain] Cd Length: 352 Bit Score: 297.63 E-value: 1.61e-97
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 10 VATLGPSSNDYNMIRALFEAGADVFRLNMSHGSHdeirERHTIIRQIEKDLDRPIAILADLQGPKLRCGVFSGDSEELVV 89
Cdd:PRK06739 6 ICTIGPASNNKETLAQLINNGMKIVRLNLSHGTH----ESHKDIIRLVKSLDDSIKILGDVQGPKIRLGEIKGEQITLQA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 90 GEPFRFDLDPAEGNARRVCLPHKEIFQALRPGATLLVNDGKIRLKVEECGADFAECTVMVGGTISNRKGVNVPDVVLPLA 169
Cdd:PRK06739 82 GDSFILHTQPVTGSSTEASVDYEGIANDVKVGSRILMNDGEVELIVEKVSTDKIETKVKTGGNISSHKGVNLPGAIVRLP 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 170 ALSPKDRKDLEFVCELGVDWIALSFVQRPEDVLEARTLVRGR----AAILSKIEKPAAVTAFAEILEVSDGIMVARGDLG 245
Cdd:PRK06739 162 AITEKDKKDIQFLLEEDVDFIACSFVRKPSHIKEIRDFIQQYketsPNLIAKIETMEAIENFQDICKEADGIMIARGDLG 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 246 VELPVQNVSPIQKRLVRACRAAAKPVIVATQMLESMIESPVPTRAEVSDVATAIYEGADAVMLSAESAAGAYPIEAVTTM 325
Cdd:PRK06739 242 VELPYQFIPLLQKMMIQECNRTNTYVITATQMLQSMVDHSIPTRAEVTDVFQAVLDGTNAVMLSAESASGEHPIESVSTL 321
|
....*....
gi 2525123055 326 NNVAEEVEH 334
Cdd:PRK06739 322 RLVSEFAEH 330
|
|
| PLN02461 |
PLN02461 |
Probable pyruvate kinase |
1-398 |
2.77e-93 |
|
Probable pyruvate kinase
Pssm-ID: 215255 [Multi-domain] Cd Length: 511 Bit Score: 292.27 E-value: 2.77e-93
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 1 MRRHRNVKIVATLGPSSNDYNMIRALFEAGADVFRLNMSHGSHDEIRERHTIIRQIEKDLDRPIAILADLQGPKLRCGVF 80
Cdd:PLN02461 17 GLRRPKTKIVCTLGPASRSVPMLEKLLRAGMNVARFNFSHGSHEYHQETLDNLRQAMANTGILCAVMLDTKGPEIRTGFL 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 81 -SGDSEELVVGEPFRFDLDPA-EGNARRVCLPHKEIFQALRPGATLLVNDGKIRLKVEECGADFAE--CTVMVGGTISNR 156
Cdd:PLN02461 97 kDGKPVQLKQGQEITITTDYSiKGDENMIAMSYKKLAVDVKPGSVILCADGTITLTVLSCDVEAGTvrCRCENSAMLGER 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 157 KGVNVPDVVLPLAALSPKDRKD-LEFVCELGVDWIALSFVQRPEDVLEARTLVrGRAA----ILSKIEKPAAVTAFAEIL 231
Cdd:PLN02461 177 KNVNLPGVVVDLPTLTEKDKEDiLQWGVPNKIDFIALSFVRKGSDLVEVRKVL-GEHAksilLISKVENQEGLDNFDDIL 255
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 232 EVSDGIMVARGDLGVELPVQNVSPIQKRLVRACRAAAKPVIVATQMLESMIESPVPTRAEVSDVATAIYEGADAVMLSAE 311
Cdd:PLN02461 256 AESDAFMVARGDLGMEIPIEKIFLAQKMMIYKCNLAGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGE 335
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 312 SAAGAYPIEAVTTMNNVAEEVE----HDPTYREVIEAsrgASRP-GVAGGIVAAAREIAETADIKVICCFTHSGTTAALT 386
Cdd:PLN02461 336 TAAGAYPELAVKTMARICREAEasldYGALFKEIMRS---APLPmSPLESLASSAVRTANKVKASLIVVLTRGGTTARLV 412
|
410
....*....|..
gi 2525123055 387 ARERPRVPILAL 398
Cdd:PLN02461 413 AKYRPAVPILSV 424
|
|
| PLN02623 |
PLN02623 |
pyruvate kinase |
5-414 |
3.50e-85 |
|
pyruvate kinase
Pssm-ID: 215334 [Multi-domain] Cd Length: 581 Bit Score: 273.34 E-value: 3.50e-85
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 5 RNVKIVATLGPSSNDYNMIRALFEAGADVFRLNMSHGSHDEIRERHTIIRQIE-KDLDRPIAILADLQGPKLRcgvfSGD 83
Cdd:PLN02623 110 RKTKIVCTIGPSTNTREMIWKLAEAGMNVARLNMSHGDHASHQKVIDLVKEYNaQSKDNVIAIMLDTKGPEVR----SGD 185
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 84 SEE---LVVGEPFRFDLDPAEGNARRVCLPHKEIFQALRPGATLLVNDGKIRLKVEECGADFAECTVMVGGTISNRKGVN 160
Cdd:PLN02623 186 LPQpimLEEGQEFTFTIKRGVSTEDCVSVNYDDFVNDVEVGDMLLVDGGMMSLAVKSKTSDSVKCEVVDGGELKSRRHLN 265
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 161 VPDVVLPLAALSPKDRKDLEFVCELGVDWIALSFVQRPEDVLEARTLVRGRAA---ILSKIEKPAAVTAFAEILEVSDGI 237
Cdd:PLN02623 266 VRGKSATLPSITEKDWEDIKFGVENKVDFYAVSFVKDAQVVHELKDYLKSCNAdihVIVKIESADSIPNLHSIITASDGA 345
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 238 MVARGDLGVELPVQNVSPIQKRLVRACRAAAKPVIVATQMLESMIESPVPTRAEVSDVATAIYEGADAVMLSAESAAGAY 317
Cdd:PLN02623 346 MVARGDLGAELPIEEVPLLQEEIIRRCRSMGKPVIVATNMLESMIVHPTPTRAEVSDIAIAVREGADAVMLSGETAHGKF 425
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 318 PIEAVTTMNNVAEEVEHDPTYREViEASRGASRPGVAGGIVAAAREIAETADIKVICCFTHSGTTAALTARERPRVPILA 397
Cdd:PLN02623 426 PLKAVKVMHTVALRTEATLPEGTT-PPNLGQAFKNHMSEMFAFHATMMANTLGTSIIVFTRTGFMAILLSHYRPSGTIFA 504
|
410
....*....|....*..
gi 2525123055 398 LTPFAATARRLCLTWGI 414
Cdd:PLN02623 505 FTNEKRIQQRLALYQGV 521
|
|
| PTZ00300 |
PTZ00300 |
pyruvate kinase; Provisional |
33-418 |
1.53e-84 |
|
pyruvate kinase; Provisional
Pssm-ID: 140321 [Multi-domain] Cd Length: 454 Bit Score: 267.69 E-value: 1.53e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 33 VFRLNMSHGSHDEIRERHTIIRQIEKDLDRPIAILADLQGPKLRCGVFSGDSEELVVGEPFRFDLDPA---EGNARRVCL 109
Cdd:PTZ00300 3 VARMNFSHGSHEYHQTTINNVRQAAAELGVNIAIALDTKGPEIRTGLFVGGEAVMERGATCYVTTDPAfadKGTKDKFYI 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 110 PHKEIFQALRPGATLLVNDGKIRLKVEECGADFA-ECTVMVGGTISNRKGVNVPDVVLPLAALSPKDRKDLEFVCELGVD 188
Cdd:PTZ00300 83 DYQNLSKVVRPGGYIYIDDGILILHVQSHEDEQTlKCTVTNAHTISDRRGVNLPGCDVDLPAVSAKDCADLQFGVEQGVD 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 189 WIALSFVQRPEDVLEARTLVRGRAA---ILSKIEKPAAVTAFAEILEVSDGIMVARGDLGVELPVQNVSPIQKRLVRACR 265
Cdd:PTZ00300 163 MIFASFIRSAEQVGEVRKALGAKGGdimIICKIENHQGVQNIDSIIEESDGIMVARGDLGVEIPAEKVVVAQKILISKCN 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 266 AAAKPVIVATQMLESMIESPVPTRAEVSDVATAIYEGADAVMLSAESAAGAYPIEAVTTMNNVAEEVEhDPTYREVIEAS 345
Cdd:PTZ00300 243 VAGKPVICATQMLESMTYNPRPTRAEVSDVANAVFNGADCVMLSGETAKGKYPNEVVQYMARICLEAQ-SAVNEYVFFNS 321
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2525123055 346 RGASRP---GVAGGIVAAAREIAETADIKVICCFTHSGTTAALTARERPRVPILALTPFAATARRLCLTWGIQCFF 418
Cdd:PTZ00300 322 IKKLQPipmSAEEAVCSSAVNSVYETKAKALVVLSNTGRSARLVAKYRPNCPIVCVTTRLQTCRQLNITQGVESVF 397
|
|
| PLN02762 |
PLN02762 |
pyruvate kinase complex alpha subunit |
2-414 |
3.35e-76 |
|
pyruvate kinase complex alpha subunit
Pssm-ID: 215407 [Multi-domain] Cd Length: 509 Bit Score: 247.74 E-value: 3.35e-76
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 2 RRHRNVKIVATLGPSSNDYNMIRALFEAGADVFRLNMSHGSHDEIRERHTIIRQIEKDLDRPIAILADLQGPKLRC---- 77
Cdd:PLN02762 22 RSTRRTKLVCTIGPACCGFEQLEALAMGGMNVARLNMCHGTREWHRDVIRRVRRLNEEKGFAVAVMMDTEGSEIHMgdlg 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 78 GVFSGDSEElvvGEPFRFDLDPAEGN--ARRVCLPHKEIFQALRPGATLLVNDGKIRLKV-EECGADF-AECT----VMV 149
Cdd:PLN02762 102 GASSAKAED---GEEWTFTVRKFDGSrpEFTIQVNYDGFAEDVKVGDELVVDGGMVRFEViEKIGPDVkCKCTdpglLLP 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 150 GGTISN-RKGVNVPDVVLPLAALSPKDRKDLEFVCELGVDWIALSFVQRPEDVLEARTLVRGRA-----AILSKIEKPAA 223
Cdd:PLN02762 179 RANLTFwRDGSLVRERNAMLPTISSKDWLDIDFGISEGVDFIAVSFVKSAEVIKHLKSYIAARSrdsdiGVIAKIESLDS 258
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 224 VTAFAEILEVSDGIMVARGDLGVELPVQNVSPIQKRLVRACRAAAKPVIVATQMLESMIESPVPTRAEVSDVATAIYEGA 303
Cdd:PLN02762 259 LKNLEEIIRASDGAMVARGDLGAQIPLEQVPSVQEKIVRLCRQLNKPVIVASQLLESMIEYPTPTRAEVADVSEAVRQRA 338
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 304 DAVMLSAESAAGAYPIEAVTTMNNVAEEVE---HDPTYREVIEASR-GASRPG-VAGGIVAAAREIAETADIKVICCFTH 378
Cdd:PLN02762 339 DALMLSGESAMGLYPEKALSVLRSVSLRMElwsREEKRHEALELPQlSSSLSDrISEEICNSAAKMANNLGVDAIFVYTK 418
|
410 420 430
....*....|....*....|....*....|....*.
gi 2525123055 379 SGTTAALTARERPRVPILALTPFAATARRLCLTWGI 414
Cdd:PLN02762 419 HGHMASLLSRNRPDCPIFAFTDTTSVRRRLNLQWGL 454
|
|
| PRK08187 |
PRK08187 |
pyruvate kinase; Validated |
2-328 |
2.24e-61 |
|
pyruvate kinase; Validated
Pssm-ID: 236178 Cd Length: 493 Bit Score: 208.33 E-value: 2.24e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 2 RRHRNVKIVATLgPS--SNDYNMIRALFEAGADVFRLNMSHGSHDEIRERHTIIRQIEKDLDRPIAILADLQGPKLRCGV 79
Cdd:PRK08187 130 PAARRTRIMVTL-PSeaADDPDFVLRLAERGMDCARINCAHDDPAAWQAMIGHLRQAERATGRRCKILMDLAGPKIRTGA 208
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 80 FSGDSEE--LVVGEPFRF----DLDPAEGNARRVCLPHKEIFQALRPGATLLVNDGKIRLKVEECGADFAECTVMVGGTI 153
Cdd:PRK08187 209 VAGPLGKtrLYTGDRLALvaqgPPRRIDEEHFQVTCTLPEILARLAVGARVWIDDGKLGARVERVGPGGALLEVTHARPK 288
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 154 SNR----KGVNVPDVVLPLAALSPKDRKDLEFVCElGVDWIALSFVQRPEDV------LEAR-TLVRGRAAILSKIEKPA 222
Cdd:PRK08187 289 GLKlkpeKGLNFPDTALDLPALTEKDRADLDFVAR-HADLVGYSFVQSPGDVealqaaLAARrPDDWRKLGLVLKIETPR 367
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 223 AVTAFAEILEVSDG-----IMVARGDLGVELPVQNVSPIQKRLVRACRAAAKPVIVATQMLESMIESPVPTRAEVSDVAT 297
Cdd:PRK08187 368 AVANLPELIVQAAGrqpfgVMIARGDLAVEIGFERLAEMQEEILWLCEAAHVPVIWATQVLEGLVKKGLPSRAEMTDAAM 447
|
330 340 350
....*....|....*....|....*....|.
gi 2525123055 298 AiyEGADAVMLSaesaAGAYPIEAVTTMNNV 328
Cdd:PRK08187 448 A--ARAECVMLN----KGPYLVEAVTFLDDL 472
|
|
| PLN02765 |
PLN02765 |
pyruvate kinase |
8-398 |
1.73e-58 |
|
pyruvate kinase
Pssm-ID: 215409 [Multi-domain] Cd Length: 526 Bit Score: 201.44 E-value: 1.73e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 8 KIVATLGPSSNDYNMIRALFEAGADVFRLNMSHGSHDEIRERHTIIRQIEKDLDRPIAILADLQGPKLRCGVFSGDSEEL 87
Cdd:PLN02765 31 KIVGTLGPKSRSVEVIEACLKAGMSVARFDFSWGDAEYHQETLENLKIAVKNTKKLCAVMLDTVGPELQVINKTEKPISL 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 88 VVGEpfRFDLDP-AEGNARRVCLP--HKEIFQALRPGATLLVND--------GKIRLKVEECGADFAECTVMVGGTISnr 156
Cdd:PLN02765 111 KAGN--TVTLTPdQSKEASSEVLPinFPGLAKAVKPGDTIFVGQylftgsetTSVWLEVDEVKGDDVVCTVKNSATLA-- 186
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 157 kG----VNVPDVVLPLAALSPKDRKDLEfvcELGV----DWIALSFVQRPEDVLEARTLVR----GRAAILSKIEKPAAV 224
Cdd:PLN02765 187 -GslftLHVSQVRIDLPTLSEKDKEVIS---TWGVpnkiDFLSLSYTRHAEDVREAREFLSslglSQTQIFAKIENVEGL 262
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 225 TAFAEILEVSDGIMVARGDLGVELPVQNVSPIQKRLVRACRAAAKPVIVaTQMLESMIESPVPTRAEVSDVATAIYEGAD 304
Cdd:PLN02765 263 THFDEILQEADGIILSRGNLGIDLPPEKVFLFQKAALYKCNMAGKPAVV-TRVVDSMTDNLRPTRAEATDVANAVLDGAD 341
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 305 AVMLSAESAAGAYPIEAVTTMNNVAEEVE----HDPTYREVIEASRG--ASRPGVAGGIVAAAREIAETadikVICCFTH 378
Cdd:PLN02765 342 AILLGAETLRGLYPVETISTVGRICAEAEkvfnQDLYFKKTVKYVGEpmSHLESIASSAVRAAIKVKAS----VIIVFTS 417
|
410 420
....*....|....*....|
gi 2525123055 379 SGTTAALTARERPRVPILAL 398
Cdd:PLN02765 418 SGRAARLIAKYRPTMPVLSV 437
|
|
| PykA2 |
COG3848 |
Phosphohistidine swiveling domain of PEP-utilizing enzymes [Signal transduction mechanisms]; |
264-467 |
3.37e-49 |
|
Phosphohistidine swiveling domain of PEP-utilizing enzymes [Signal transduction mechanisms];
Pssm-ID: 443058 Cd Length: 321 Bit Score: 171.24 E-value: 3.37e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 264 CRAAAKPVIVATQMLESMIESPVPTRAEVSDVATAIYEGADAVMLSAESAAGAYPIEAVTTMNNVAEEVEHDPTYREVIE 343
Cdd:COG3848 2 CNAAGKPVITATQMLDSMMRNPRPTRAEAADVANAIFDGTDAIMLSGETAAGKYPVEAVVTMVRIAERAEEDLEYREQRV 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 344 ASRGASRPGVAGGIVAAAREIAETADIKVICCFTHSGTTAALTARERPRVPILALTPFAATARRLCLTWGIQCFFTGEVD 423
Cdd:COG3848 82 PRAKESSTTITDAISHAVATTAADLGAAAIITATESGATARMVSKYRPKAPIIAVTPSERVARQLSLVWGVYPLLVEESA 161
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 2525123055 424 RFKMAVVSAARAAREGGYATEQDQIVVTAGVPFNEPGTTNILRV 467
Cdd:COG3848 162 STDEMFAVAVALALEAGLVKDGDLVVITAGVPVGVSGTTNLLKV 205
|
|
| PRK14725 |
PRK14725 |
pyruvate kinase; Provisional |
2-333 |
1.82e-42 |
|
pyruvate kinase; Provisional
Pssm-ID: 237804 Cd Length: 608 Bit Score: 158.96 E-value: 1.82e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 2 RRHRNVKIVATLgPSS--NDYNMIRALFEAGADVFRLNMSHGSHDEIRERHTIIRQIEKDLDRPIAILADLQGPKLRCG- 78
Cdd:PRK14725 136 PSGRPTRIMVTL-PTEaaDDPDLVRRLLAAGMDIARINCAHDDPEAWRAMIANVRTAEEELGRRCRIAMDLAGPKLRTGp 214
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 --------------------------------------------------------------------------------
Cdd:PRK14725 215 iapgprviklrptrdalgrvltparlwltasespppspppgpvglpvdpewlarlepgdelrftdargkkrkltvtevdd 294
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 79 ----------------------------------------VFSGDseELVV---GEPFRFDLDPAEGnARRVC-LPhkEI 114
Cdd:PRK14725 295 egvlaegsqtaylangtllrlgrhdstrvgglppveqklrLKVGD--RLVLtrdDAPGDPAQGDAPP-ARISCtLP--EA 369
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 115 FQALRPGATLLVNDGKIRLKVEECGADFAECTV----MVGGTISNRKGVNVPDVVLPLAALSPKDRKDLEFVCELGvDWI 190
Cdd:PRK14725 370 FRAARVGERVWFDDGKIGAVVVKVEADEVELRItharPGGSKLKAGKGINLPDSHLPLPALTDKDLEDLAFVAKHA-DIV 448
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 191 ALSFVQRPEDVLEARTLVRGRAA----ILSKIEKPAAVTAFAEIL-----EVSDGIMVARGDLGVELPVQNVSPIQKRLV 261
Cdd:PRK14725 449 ALSFVRSPEDVRLLLDALEKLGAddlgVVLKIETRRAFENLPRILleamrHPRFGVMIARGDLAVEVGFERLAEVQEEIL 528
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2525123055 262 RACRAAAKPVIVATQMLESMIESPVPTRAEVSDVATAIYegADAVMLSaesaAGAYPIEAVTTMNNVAEEVE 333
Cdd:PRK14725 529 WLCEAAHVPVIWATQVLESLAKKGLPSRAEITDAAMALR--AECVMLN----KGPHIVEAVRVLDDILRRME 594
|
|
| PK_C |
pfam02887 |
Pyruvate kinase, alpha/beta domain; As well as being found in pyruvate kinase this family is ... |
357-467 |
4.12e-32 |
|
Pyruvate kinase, alpha/beta domain; As well as being found in pyruvate kinase this family is found as an isolated domain in some bacterial proteins.
Pssm-ID: 460738 [Multi-domain] Cd Length: 114 Bit Score: 118.74 E-value: 4.12e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 357 IVAAAREIAETADIKVICCFTHSGTTAALTARERPRVPILALTPFAATARRLCLTWGIQCFFTGEVDRFKMAVVSAARAA 436
Cdd:pfam02887 3 IAHAAVEAAEELGAKAIVVLTESGYTARLISRYRPGVPIIAVTPNELTARQLALYWGVYPVLFDEAETTDEMLRRAVKVA 82
|
90 100 110
....*....|....*....|....*....|.
gi 2525123055 437 REGGYATEQDQIVVTAGVPFNEPGTTNILRV 467
Cdd:pfam02887 83 KEAGLVKKGDLVVITAGVPFGVSGTTNTLKV 113
|
|
| CitE |
COG2301 |
Citrate lyase beta subunit [Carbohydrate transport and metabolism]; |
172-272 |
7.91e-03 |
|
Citrate lyase beta subunit [Carbohydrate transport and metabolism];
Pssm-ID: 441876 Cd Length: 288 Bit Score: 38.21 E-value: 7.91e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525123055 172 SPKDRKDLEFVCELGVDWIALSFVQRPEDVLEARTLVR------GRAAILSKIEKPAAVTAFAEILEVSDGIMVAR---- 241
Cdd:COG2301 74 TPWGLDDLAALVGAGLDGIVLPKVESAEDVRALAALLTeleaegGSIPLMALIETARGLLNAAEIAAASPRVEALVfgae 153
|
90 100 110
....*....|....*....|....*....|....*.
gi 2525123055 242 ---GDLGVELPVQN--VSPIQKRLVRACRAAAKPVI 272
Cdd:COG2301 154 dlaADLGARRTRDGdeLLYARSRIVLAARAAGLAAI 189
|
|
| |
