|
Name |
Accession |
Description |
Interval |
E-value |
| PRK10614 |
PRK10614 |
multidrug efflux system subunit MdtC; Provisional |
1-1024 |
0e+00 |
|
multidrug efflux system subunit MdtC; Provisional
Pssm-ID: 182589 [Multi-domain] Cd Length: 1025 Bit Score: 2068.56 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 1 MKFFALFIYRPVATILISLAITLCGVLGFRLLPVAPLPQVDFPVIMVSASLPGASPETMASSVATPLERSLGRIAGVNEM 80
Cdd:PRK10614 1 MKFFALFIYRPVATILLSLAITLCGILGFRLLPVAPLPQVDFPVIMVSASLPGASPETMASSVATPLERSLGRIAGVNEM 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 81 TSSSSLGSTRIILEFSFDRDINGAARDVQAAINAAQSLLPSGMPSRPTYRKANPSDAPIMILTLTSDTYSQGQLYDFAST 160
Cdd:PRK10614 81 TSSSSLGSTRIILQFDFDRDINGAARDVQAAINAAQSLLPSGMPSRPTYRKANPSDAPIMILTLTSDTYSQGQLYDFAST 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 161 QLAQTISQINGVGDVSVGGSSLPAVRVGLNPQALFNQGVSLDDVRSAISNANVRKPQGAIEDGSHRWQIHTNDELKTAAE 240
Cdd:PRK10614 161 QLAQTISQIDGVGDVDVGGSSLPAVRVGLNPQALFNQGVSLDDVRQAISNANVRRPQGAVEDGTHRWQIQTNDELKTAAE 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 241 YQPLIIHYNNGAAVRLSDVASVTDSVQDVRNAGMTNAKPAILLMIRKLPEANIIETVNSIRARLPELQQTIPAAIDLQIA 320
Cdd:PRK10614 241 YQPLIIHYNNGAAVRLGDVATVTDSVQDVRNAGMTNAKPAILLMIRKLPEANIIQTVDRIRAKLPELRETIPAAIDLQIA 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 321 QDRSPTIRASLEEVEQTLVISVALVILVVFLFLRSGRATLIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMALTIATGFVV 400
Cdd:PRK10614 321 QDRSPTIRASLEEVEQTLAISVALVILVVFLFLRSGRATLIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMALTIATGFVV 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 401 DDAIVVLENISRHLEAGVNPLQAALQGTREVGFTVLSMSLSLVAVFLPLLLMGGLPGRLLREFAVTLSVAIGISLIISLT 480
Cdd:PRK10614 401 DDAIVVLENISRHLEAGMKPLQAALQGVREVGFTVLSMSLSLVAVFLPLLLMGGLPGRLFREFAVTLSVAIGISLLVSLT 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 481 LTPMMCGWMLKRSKPHSQPRRKGFGRVLLAMQEGYGKSLKWVLNHTRLVGLVLIGTIVLNVWLYISIPKTFFPEQDTGVL 560
Cdd:PRK10614 481 LTPMMCAWLLKSSKPREQKRLRGFGRMLVALQQGYGRSLKWVLNHTRWVGVVLLGTIALNVWLYISIPKTFFPEQDTGRL 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 561 MGGIQADQSISFQAMRGKLQDFMKIIREDKAVDNVTGFTGGSRVNSGMMFITLKPRGERNETAQQVIDRLRVKLAKEPGA 640
Cdd:PRK10614 561 MGFIQADQSISFQAMRGKLQDFMKIIRDDPAVDNVTGFTGGSRVNSGMMFITLKPLSERSETAQQVIDRLRVKLAKEPGA 640
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 641 NLFLMAVQDIRVGGRQANASYQYTLLSDDLAALREWEPKIRKALAALPQLADVNSDQQDNGAEMALTYDRETMSRLGINV 720
Cdd:PRK10614 641 NLFLMAVQDIRVGGRQSNASYQYTLLSDDLAALREWEPKIRKALAALPELADVNSDQQDKGAEMALTYDRDTMARLGIDV 720
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 721 EAANSLLNNAFGQREISTIYQPMNQYKVVMEVDPRYTQDISALDKMFVINNDGKAIPLSYFASWQPANAPLSVNHQGLSA 800
Cdd:PRK10614 721 QAANSLLNNAFGQRQISTIYQPLNQYKVVMEVDPRYTQDISALEKMFVINNEGKAIPLSYFAKWQPANAPLSVNHQGLSA 800
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 801 ASTISFNLPAGSSLSEASDAINRAMTQLGVPSTVRGSFAGTAQVFQETMNSQVILILAAIATVYIVLGVLYESYVHPLTI 880
Cdd:PRK10614 801 ASTISFNLPTGKSLSDASAAIERAMTQLGVPSTVRGSFAGTAQVFQETMNSQLILILAAIATVYIVLGILYESYVHPLTI 880
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 881 LSTLPSAGVGALLALELFDAPFSLIALIGIMLLIGIVKKNAIMMVDFALDAQRNGNLSPEEAIFQACLLRFRPIMMTTLA 960
Cdd:PRK10614 881 LSTLPSAGVGALLALELFNAPFSLIALIGIMLLIGIVKKNAIMMVDFALEAQRNGNLTAQEAIFQACLLRFRPIMMTTLA 960
|
970 980 990 1000 1010 1020
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2526274827 961 ALFGALPLVISGGDGSELRQPLGITIVGGLVMSQLLTLYTTPVVYLFFDRLRLRVARKNRTTVT 1024
Cdd:PRK10614 961 ALFGALPLVLSGGDGAELRQPLGITIVGGLVMSQLLTLYTTPVVYLFFDRLRLRFSRKPKQTVT 1024
|
|
| RND_permease_2 |
NF033617 |
multidrug efflux RND transporter permease subunit; |
4-1010 |
0e+00 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 411236 [Multi-domain] Cd Length: 1009 Bit Score: 1405.15 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 4 FALFIYRPVATILISLAITLCGVLGFRLLPVAPLPQVDFPVIMVSASLPGASPETMASSVATPLERSLGRIAGVNEMTSS 83
Cdd:NF033617 1 SDVFIKRPVATLLLSLLILLLGLLAFRKLPVREYPEVDFPTITVSTSYPGASPELMQSSITQPLEQQLAQIEGIDEMTSQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 84 SSLGSTRIILEFSFDRDINGAARDVQAAINAAQSLLPSGMPSRPTYRKANPSDAPIMILTLTSDTYSQGQLYDFASTQLA 163
Cdd:NF033617 81 SSLGYSTITLQFRLGTDLDVALSEVQAAINAAQSLLPSEAPDPPVYRKANSADTPIMYIGLTSEEMPRGQLTDYAERVLA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 164 QTISQINGVGDVSVGGSSLPAVRVGLNPQALFNQGVSLDDVRSAISNANVRKPQGAIEDGSHRWQIHTNDELKTAAEYQP 243
Cdd:NF033617 161 PKLSQINGVGSVDVSGGQRPAMRVWLDPEKMAARGLTADDVRSALNSNNVNSPKGAVRGDSVVSTVRANDQLKTAEDYED 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 244 LIIHYN-NGAAVRLSDVASVTDSVQDVRNAGMTNAKPAILLMIRKLPEANIIETVNSIRARLPELQQTIPAAIDLQIAQD 322
Cdd:NF033617 241 LVIKYAdNGAPVRLGDVATVELGAENVRNRAWANGVPAVVLGINRQPGANPIEVADEIRALLPELQETLPKNIKVNVLYD 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 323 RSPTIRASLEEVEQTLVISVALVILVVFLFLRSGRATLIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMALTIATGFVVDD 402
Cdd:NF033617 321 RTRFIRASIDEVESTLLEAVALVILVVFLFLRNLRATLIPAVTVPLSLIGTFAVMYLFGFSINLLTLMALVLAIGLVVDD 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 403 AIVVLENISRHLEAGVNPLQAALQGTREVGFTVLSMSLSLVAVFLPLLLMGGLPGRLLREFAVTLSVAIGISLIISLTLT 482
Cdd:NF033617 401 AIVVVENIHRHIEEGESPLEAALKGAREIGFTVIAMTLTLVAVYLPILFMGGLTGRLFREFAVTLAGAVIISGIVALTLT 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 483 PMMCGWMLKRskpHSQPRR--KGFGRVLLAMQEGYGKSLKWVLNHTRLVGLVLIGTIVLNVWLYISIPKTFFPEQDTGVL 560
Cdd:NF033617 481 PMMCSRLLKA---NEKPGRfaRAVDRFFDGLTARYGRGLKWVLKHRPLTLVVALATLALLPLLYVFIPKELAPSEDRGVI 557
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 561 MGGIQADQSISFQAMRGKLQDFMKIIREDKAVDNVTGFTGGSRVNS---GMMFITLKPRGERNETAQQVIDRLRVKLAKE 637
Cdd:NF033617 558 FGMIQAPQSISLDYMSAKMRDVEKILSSDPEVQSLTSFNGVGGNPGdntGFGIINLKPWDERDVSAQEIIDRLRPKLAKV 637
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 638 PGANLFLMAVQDIRVGGRQANASYQYTLLSDDLAALREWEPKIRKALAALPQLADVNSDQQDNGAEMALTYDRETMSRLG 717
Cdd:NF033617 638 PGMDLFLFPLQDLPGGAGSSLPQYQVTLTPSDYDSLFTWAEKLKEKLRKSPQFADVDSDLQDKGPELNVDIDRDKAARLG 717
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 718 INVEAANSLLNNAFGQREISTIYQPMNQYKVVMEVDPRYTQDISALDKMFVINNDGKAIPLSYFASWQPANAPLSVNHQG 797
Cdd:NF033617 718 ISMQDIGSTLEVAFGQRQVNTIYTDGNQYKVVLEVDRRYRLNPEALNQIYVRSNDGKLVPLSTLAKIEERAAPLSLNHFN 797
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 798 LSAASTISFNLPAGSSLSEASDAINRAMTQLgVPSTVRGSFAGTAQVFQETMNSQVILILAAIATVYIVLGVLYESYVHP 877
Cdd:NF033617 798 QFNSATLSFNLAPGVSLGEAIEALDQAAKEL-LPSGISGSFQGAARAFQEEGSSLLFLFLLALAAIYLVLAIQYESFVDP 876
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 878 LTILSTLPSAGVGALLALELFDAPFSLIALIGIMLLIGIVKKNAIMMVDFALDAQRNGNLSPEEAIFQACLLRFRPIMMT 957
Cdd:NF033617 877 LTILSTVPLAGCGALLALALGGQSMNIYAQIGLITLIGLVKKNGILMVEFANELQRHQGLSRREAIYQAAALRLRPILMT 956
|
970 980 990 1000 1010
....*....|....*....|....*....|....*....|....*....|...
gi 2526274827 958 TLAALFGALPLVISGGDGSELRQPLGITIVGGLVMSQLLTLYTTPVVYLFFDR 1010
Cdd:NF033617 957 TLAMLLGAIPLMLSTGAGAESRFPLGIVIVGGLGVGTLFTLFVLPVVYLLLAR 1009
|
|
| ACR_tran |
pfam00873 |
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ... |
3-1009 |
0e+00 |
|
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.
Pssm-ID: 395701 [Multi-domain] Cd Length: 1021 Bit Score: 1185.94 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 3 FFALFIYRPVATILISLAITLCGVLGFRLLPVAPLPQVDFPVIMVSASLPGASPETMASSVATPLERSLGRIAGVNEMTS 82
Cdd:pfam00873 1 MSKFFIRRPIFTLVLAIAILLAGILSFFSLPVDAFPEIAPPTVQVSTSYPGASPEEVEDTVTQPIEQAMNGLDGLKYMSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 83 SSSLGSTRIILEFSFDRDINGAARDVQAAINAAQSLLPSGMpSRPTYRKANPSDAPIMILTLTSD--TYSQGQLYDFAST 160
Cdd:pfam00873 81 QSSYGLSSITLTFELGTDIDIARQDVQNRLQLATPLLPEGV-QRPGISVIKTSLGPIMVLAVTSPdgSYTQTDLRDYADT 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 161 QLAQTISQINGVGDVSVGGSSLPAVRVGLNPQALFNQGVSLDDVRSAISNANVRKPQGAIEDGSHRWQIHTNDELKTAAE 240
Cdd:pfam00873 160 NIKPQLSRVPGVGDVQLFGGSEYAMRIWLDPQKLARYGLTLTDVVSALKEQNVNIGAGQLEGQGLQALIRAQGQLQSAED 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 241 YQPLIIHYNNGAAVRLSDVASVTDSVQDVRNAGMTNAKPAILLMIRKLPEANIIETVNSIRARLPELQQTIPAAIDLQIA 320
Cdd:pfam00873 240 FEKIIVKNQDGSPVRLRDVATVELGSELYRGFATFNGKPAVGLGVQKLPGANAIETADAVRAKLAELKPTFPQGVEIVVV 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 321 QDRSPTIRASLEEVEQTLVISVALVILVVFLFLRSGRATLIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMALTIATGFVV 400
Cdd:pfam00873 320 YDTTPFIRASIEEVVKTLLEAIVLVILVMFLFLQNWRATLIPAIAIPLSLLGTFAVMKAFGFSINTLTLGGLVLAIGLVV 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 401 DDAIVVLENISRHLEA-GVNPLQAALQGTREVGFTVLSMSLSLVAVFLPLLLMGGLPGRLLREFAVTLSVAIGISLIISL 479
Cdd:pfam00873 400 DDAIVVVENIERVLEEnGLKPLEAAYKSMGEIGGALVAIALVLSAVFLPILFLGGLTGRIFRQFAITIVLAILLSVLVAL 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 480 TLTPMMCGWMLK-RSKPHSQPRRKGFGRVLLAMQEGYGKSLKWVLNHTRLVGLVLIGTIVLNVWLYISIPKTFFPEQDTG 558
Cdd:pfam00873 480 TLTPALCATLLKpRREPKHGGFFRWFNRMFDRLTRGYAKLLAKVLRHTAVVLLVALLLVVGSVWLFVRIPTEFLPEEDEG 559
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 559 VLMGGIQADQSISFQAMRGKLQDFMKIIREDKAVDNVTGFTGGS------RVNSGMMFITLKPRGER---NETAQQVIDR 629
Cdd:pfam00873 560 VFVTSAQLPPGVSLDQTQRVMKQVEKILKEKPEVESVFAVTGFAfsgdnnGPNSGDAFISLKPWKERpgpEKSVQALIER 639
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 630 LRVKLAKEPGANLFLMAVQDIRV--GGRQANASYQYTLLSDDLAALREWEPKIRKALAALPQLADVNSDQQDNGAEMALT 707
Cdd:pfam00873 640 LRKALKQIPGANVFLFQPIQLRGlgTISGFRSDLQVKIFGDDLDALDEARNQILAALAQLPGLSDVRSDGQEDQPQLQVN 719
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 708 YDRETMSRLGINVEAANSLLNNAFGQREISTIYQPMNQYKVVMEVDPRYTQDISALDKMFVINNDGKAIPLSYFASWQPA 787
Cdd:pfam00873 720 IDREKAARLGVSIQDINDTLSTALGGSYVNDFPEGGRVYDVVVQLPEDFRSSPEDIGQLYVRNPYGKMIPLSAFAKIEWG 799
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 788 NAPLSVNHQGLSAASTISFNLPAGSSLSEASDAINRAMTQLGVPSTVRGSFAGTAQVFQETMNSQVILILAAIATVYIVL 867
Cdd:pfam00873 800 YGPPSINRYNGFRSIVISGNVAAGDSLGDAMEAMAQIAKQVKLPPGYGYTWTGQFEQEQLAGNSLPILIALALLVVFLVL 879
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 868 GVLYESYVHPLTILSTLPSAGVGALLALELFDAPFSLIALIGIMLLIGIVKKNAIMMVDFALDAQRNGNLSPEEAIFQAC 947
Cdd:pfam00873 880 AALYESWSDPLSIMLTVPLALVGALLALWLRGLPNSVYAQVGLILLIGLAVKNAILMVEFANELREQEGKSLEEAILEAC 959
|
970 980 990 1000 1010 1020
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2526274827 948 LLRFRPIMMTTLAALFGALPLVISGGDGSELRQPLGITIVGGLVMSQLLTLYTTPVVYLFFD 1009
Cdd:pfam00873 960 RLRLRPILMTALAAILGVLPLALSTGAGSELQQPLGIVVFGGLVTSTVLTLLVVPVFYVLFH 1021
|
|
| AcrB |
COG0841 |
Multidrug efflux pump subunit AcrB [Defense mechanisms]; |
1-1015 |
0e+00 |
|
Multidrug efflux pump subunit AcrB [Defense mechanisms];
Pssm-ID: 440603 [Multi-domain] Cd Length: 1015 Bit Score: 1166.03 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 1 MKFFALFIYRPVATILISLAITLCGVLGFRLLPVAPLPQVDFPVIMVSASLPGASPETMASSVATPLERSLGRIAGVNEM 80
Cdd:COG0841 1 MNLSRFFIRRPVAAIVLSLLILLAGLLAYLRLPVEQFPDIDPPTVTVSTTYPGASPEEVESTVTTPIEEALNGVEGIKYI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 81 TSSSSLGSTRIILEFSFDRDINGAARDVQAAINAAQSLLPSGMpSRPTYRKANPSDAPIMILTLTSDTYSQGQLYDFAST 160
Cdd:COG0841 81 TSTSSEGSSSITVEFELGTDIDEALVDVQNAVDRARSDLPEDV-EPPGVTKVNPSDFPVMVLALSSDDLDELELSDYAER 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 161 QLAQTISQINGVGDVSVGGSSLPAVRVGLNPQALFNQGVSLDDVRSAISNANVRKPQGAIEDGSHRWQIHTNDELKTAAE 240
Cdd:COG0841 160 NIKDRLERVPGVGQVQIFGGREREIRIWLDPDKLAAYGLTLADVANAIRAQNVDVPAGRIGGGDREYTVRTNGRLKTPEE 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 241 YQPLIIHYNNGAAVRLSDVASVTDSVQDVRNAGMTNAKPAILLMIRKLPEANIIETVNSIRARLPELQQTIPAAIDLQIA 320
Cdd:COG0841 240 FENIVIRTNDGSVVRLGDVARVEDGAEDYRSIARLNGKPAVGLAIQKQPGANALEVADAVRAKLEELQASLPEGVELTIV 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 321 QDRSPTIRASLEEVEQTLVISVALVILVVFLFLRSGRATLIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMALTIATGFVV 400
Cdd:COG0841 320 YDQSEFIRASIEEVVKTLLEAILLVVLVVFLFLRSWRATLIPAVAIPVSLIGTFAVMYLLGFSLNILTLFALVLAIGIVV 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 401 DDAIVVLENISRHLEAGVNPLQAALQGTREVGFTVLSMSLSLVAVFLPLLLMGGLPGRLLREFAVTLSVAIGISLIISLT 480
Cdd:COG0841 400 DDAIVVVENIERHMEEGLSPLEAAIKGAREVAGAVIASTLTLVAVFLPLAFMGGITGQLFRQFALTVAIALLISLFVALT 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 481 LTPMMCGWMLKRSKPHSQPR-RKGFGRVLLAMQEGYGKSLKWVLNHTRLVGLVLIGTIVLNVWLYISIPKTFFPEQDTGV 559
Cdd:COG0841 480 LTPALCARLLKPHPKGKKGRfFRAFNRGFDRLTRGYGRLLRWALRHRKLTLLVALALLALSVLLFGRLPTEFFPEEDQGQ 559
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 560 LMGGIQADQSISFQAMRGKLQDFMKIIREDKAVDNVTGFTG----GSRVNSGMMFITLKPRGERNETAQQVIDRLRVKLA 635
Cdd:COG0841 560 IIVSVQLPPGTSLERTEAVVRQVEEILLEVPEVESVFSVVGfsggGSGSNSGTIFVTLKPWDERDRSADEIIARLREKLA 639
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 636 KEPGANLFLMAVQDirvGGRQANASYQYTLLSDDLAALREWEPKIRKALAALPQLADVNSDQQDNGAEMALTYDRETMSR 715
Cdd:COG0841 640 KIPGARVFVFQPPA---GGLGSGAPIEVQLQGDDLEELAAAAEKLLAALRQIPGLVDVRSDLQLGKPELQLDIDREKAAA 716
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 716 LGINVEAANSLLNNAFGQREISTIYQPMNQYKVVMEVDPRYTQDISALDKMFVINNDGKAIPLSYFASWQPANAPLSVNH 795
Cdd:COG0841 717 LGVTVADVASTLRAALGGRYVNDFNRGGREYDVRVQAPEEDRNSPEDLENLYVRTPDGEMVPLSSVATIEEGTGPSSINR 796
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 796 QGLSAASTISFNLPAGSSLSEASDAINRAMTQLGVPSTVRGSFAGTAQVFQETMNSQVILILAAIATVYIVLGVLYESYV 875
Cdd:COG0841 797 YNGQRSVTVSANLAPGVSLGEALAAIEELAAELKLPPGVSIEFTGQAEEEQESFSSLGLAFLLALLLVYLVLAAQFESFI 876
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 876 HPLTILSTLPSAGVGALLALELFDAPFSLIALIGIMLLIGIVKKNAIMMVDFALDAQRNGnLSPEEAIFQACLLRFRPIM 955
Cdd:COG0841 877 QPLIILLTVPLALIGALLGLLLTGTPLNIYSQIGLIMLIGIVVKNAILLVDFANQLREEG-MSLREAILEAARLRLRPIL 955
|
970 980 990 1000 1010 1020
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 956 MTTLAALFGALPLVISGGDGSELRQPLGITIVGGLVMSQLLTLYTTPVVYLFFDRLRLRV 1015
Cdd:COG0841 956 MTSLATILGLLPLALGTGAGAEFRQPLGIAVIGGLLFSTLLTLFVVPVLYVLLDRLRRRL 1015
|
|
| PRK10503 |
PRK10503 |
MdtB/MuxB family multidrug efflux RND transporter permease subunit; |
6-1020 |
0e+00 |
|
MdtB/MuxB family multidrug efflux RND transporter permease subunit;
Pssm-ID: 182501 [Multi-domain] Cd Length: 1040 Bit Score: 1067.81 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 6 LFIYRPVATILISLAITLCGVLGFRLLPVAPLPQVDFPVIMVSASLPGASPETMASSVATPLERSLGRIAGVNEMTSSSS 85
Cdd:PRK10503 15 LFILRPVATTLLMVAILLAGIIGYRALPVSALPEVDYPTIQVVTLYPGASPDVMTSAVTAPLERQFGQMSGLKQMSSQSS 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 86 LGSTRIILEFSFDRDINGAARDVQAAINAAQSLLPSGMPSRPTYRKANPSDAPIMILTLTSDTYSQGQLYDFASTQLAQT 165
Cdd:PRK10503 95 GGASVITLQFQLTLPLDVAEQEVQAAINAATNLLPSDLPNPPVYSKVNPADPPIMTLAVTSTAMPMTQVEDMVETRVAQK 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 166 ISQINGVGDVSVGGSSLPAVRVGLNPQALFNQGVSLDDVRSAISNANVRKPQGAIEDGSHRWQIHTNDELKTAAEYQPLI 245
Cdd:PRK10503 175 ISQVSGVGLVTLSGGQRPAVRVKLNAQAIAALGLTSETVRTAITGANVNSAKGSLDGPTRAVTLSANDQMQSAEEYRQLI 254
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 246 IHYNNGAAVRLSDVASVTDSVQDVRNAGMTNAKPAILLMIRKLPEANIIETVNSIRARLPELQQTIPAAIDLQIAQDRSP 325
Cdd:PRK10503 255 IAYQNGAPIRLGDVATVEQGAENSWLGAWANKQQAIVMNVQRQPGANIIATADSIRQMLPQLTESLPKSVKVTVLSDRTT 334
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 326 TIRASLEEVEQTLVISVALVILVVFLFLRSGRATLIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMALTIATGFVVDDAIV 405
Cdd:PRK10503 335 NIRASVDDTQFELMLAIALVVMIIYLFLRNIPATIIPGVAVPLSLIGTFAVMVFLDFSINNLTLMALTIATGFVVDDAIV 414
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 406 VLENISRHLEAGVNPLQAALQGTREVGFTVLSMSLSLVAVFLPLLLMGGLPGRLLREFAVTLSVAIGISLIISLTLTPMM 485
Cdd:PRK10503 415 VIENISRYIEKGEKPLAAALKGAGEIGFTIISLTFSLIAVLIPLLFMGDIVGRLFREFAVTLAVAILISAVVSLTLTPMM 494
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 486 CGWMLkrsKPHSQPRRKGFGRVLLAMQE----GYGKSLKWVLNHTRLVGLVLIGTIVLNVWLYISIPKTFFPEQDTGVLM 561
Cdd:PRK10503 495 CARML---SQESLRKQNRFSRASERMFDrviaAYGRGLAKVLNHPWLTLSVALSTLLLTVLLWIFIPKGFFPVQDNGIIQ 571
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 562 GGIQADQSISFQAMRGKLQDFMKIIREDKAVDNVTGFTG----GSRVNSGMMFITLKPRGERNETAQQVIDRLRVKLAKE 637
Cdd:PRK10503 572 GTLQAPQSSSFANMAQRQRQVADVILQDPAVQSLTSFVGvdgtNPSLNSARLQINLKPLDERDDRVQKVIARLQTAVAKV 651
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 638 PGANLFLMAVQDIRVGGRQANASYQYTLLSDDLAALREWEPKIRKALAALPQLADVNSDQQDNGAEMALTYDRETMSRLG 717
Cdd:PRK10503 652 PGVDLYLQPTQDLTIDTQVSRTQYQFTLQATSLDALSTWVPKLMEKLQQLPQLSDVSSDWQDKGLVAYVNVDRDSASRLG 731
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 718 INVEAANSLLNNAFGQREISTIYQPMNQYKVVMEVDPRYTQDISALDKMFVINNDGKAIPLSYFASWQPANAPLSVNHQG 797
Cdd:PRK10503 732 ISMADVDNALYNAFGQRLISTIYTQANQYRVVLEHNTENTPGLAALDTIRLTSSDGGVVPLSSIATIEQRFGPLSINHLD 811
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 798 LSAASTISFNLPAGSSLSEASDAINRAMTQLGVPSTVRGSFAGTAQVFQETMNSQVILILAAIATVYIVLGVLYESYVHP 877
Cdd:PRK10503 812 QFPSTTISFNVPDGYSLGDAVQAIMDTEKTLNLPADITTQFQGSTLAFQSALGSTVWLIVAAVVAMYIVLGVLYESFIHP 891
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 878 LTILSTLPSAGVGALLALELFDAPFSLIALIGIMLLIGIVKKNAIMMVDFALDAQRNGNLSPEEAIFQACLLRFRPIMMT 957
Cdd:PRK10503 892 ITILSTLPTAGVGALLALMIAGSELDVIAIIGIILLIGIVKKNAIMMIDFALAAEREQGMSPRDAIYQACLLRFRPILMT 971
|
970 980 990 1000 1010 1020
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2526274827 958 TLAALFGALPLVISGGDGSELRQPLGITIVGGLVMSQLLTLYTTPVVYLFFDRLRLRVARKNR 1020
Cdd:PRK10503 972 TLAALLGALPLMLSTGVGAELRRPLGICMVGGLIVSQVLTLFTTPVIYLLFDRLALYTKSRFP 1034
|
|
| 2A0602 |
TIGR00915 |
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins ... |
7-1024 |
1.70e-173 |
|
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins scoring above the trusted cutoff (1000) form a tight clade within the RND (Resistance-Nodulation-Cell Division) superfamily. Proteins scoring greater than the noise cutoff (100) appear to form a larger clade, cleanly separated from more distant homologs that include cadmium/zinc/cobalt resistance transporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]
Pssm-ID: 273335 [Multi-domain] Cd Length: 1044 Bit Score: 534.69 E-value: 1.70e-173
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 7 FIYRPVATILISLAITLCGVLGFRLLPVAPLPQVDFPVIMVSASLPGASPETMASSVATPLERSLGRIAGVNEMTSSS-S 85
Cdd:TIGR00915 5 FIDRPIFAWVIAIIIMLAGTLSILSLPVSQYPSIAPPAITVSASYPGASAQTVQDTVTQVIEQNMNGIDGLRYMSSSSdS 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 86 LGSTRIILEFSFDRDINGAARDVQAAINAAQSLLPSGMpSRPTYRKANPSDAPIMILTLTSD--TYSQGQLYDFASTQLA 163
Cdd:TIGR00915 85 DGSMTITLTFEQGTDPDIAQVQVQNKLQLATPLLPQEV-QRQGVRVEKASSNFLMVIGLVSDdgSMTKEDLSDYAASNMV 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 164 QTISQINGVGDVSVGGSsLPAVRVGLNPQALFNQGVSLDDVRSAISNANVRKPQG------AIEDGSHRWQIHTNDELKT 237
Cdd:TIGR00915 164 DPLSRLEGVGDVQLFGS-QYAMRIWLDPAKLNSYQLTPADVISAISAQNAQISAGqlgglpAVPGQQLNATIIAQTRLQT 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 238 AAEYQPLIIHYN-NGAAVRLSDVASVTDSVQDVRNAGMTNAKPAILLMIRKLPEANIIETVNSIRARLPELQQTIPAAID 316
Cdd:TIGR00915 243 PEQFENILLKVNtDGSQVRLKDVARVELGGENYSISARFNGKPASGLAIKLATGANALDTAKAVKAELAVLEPFFPQGMK 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 317 LQIAQDRSPTIRASLEEVEQTLVISVALVILVVFLFLRSGRATLIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMALTIAT 396
Cdd:TIGR00915 323 YVYPYDTTPFVEASIEEVVHTLIEAIVLVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFAMVLAI 402
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 397 GFVVDDAIVVLENISRHL-EAGVNPLQAALQGTREVGFTVLSMSLSLVAVFLPLLLMGGLPGRLLREFAVTLSVAIGISL 475
Cdd:TIGR00915 403 GLLVDDAIVVVENVERVMaEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMALSV 482
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 476 IISLTLTPMMCGWMLKRSKPHSQPRRKG-----FGRVLLAMQEGYGKSLKWVLNHTRLVGLVLIGTIVLNVWLYISIPKT 550
Cdd:TIGR00915 483 LVALILTPALCATMLKPIEKGEHHEKKGgffgwFNRMFDSSTHGYENGVGKILRRRGRYLLVYVLLVGGMVFLFVRLPTS 562
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 551 FFPEQDTGVLMGGIQADQSISFQAMRGKLQD-----FMKIIREDKAVDNVTGFT-GGSRVNSGMMFITLKPRGER---NE 621
Cdd:TIGR00915 563 FLPDEDQGVFMTIVQLPAGATAERTQAVLAQvtkylLAKEKANVESVFTVNGFSfAGRGQNMGMAFIRLKDWEERtgkEN 642
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 622 TAQQVIDRLRVKLAKEPGANLFLMAVQDIRVGGRQANASYQytlLSD----DLAALREWEPKIRKALAALPQLADVNSDQ 697
Cdd:TIGR00915 643 SVFAIAGRATGHFMQIKDAMVIAFVPPAILELGNATGFDFF---LQDraglGHEALLQARNQLLGLAAQNPALTRVRPNG 719
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 698 QDNGAEMALTYDRETMSRLGINVEAANSLLNNAFGQREISTIYQPMNQYKVVMEVDPRYTQDISALDKMFVINNDGKAIP 777
Cdd:TIGR00915 720 LEDEPQLKIDIDREKAQALGVSIADINTTLSTAWGSSYVNDFIDRGRVKRVYVQAEEDARMSPEDINKWYVRNASGEMVP 799
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 778 LSYFASWQPAN-APLSVNHQGLSAAStISFNLPAGSSLSEASDAINRAMTQLgvPSTVrgSFAGTAQVFQETMN-SQVIL 855
Cdd:TIGR00915 800 FSAFATVRWEYgSPQLERYNGLPSME-ILGSAAPGVSTGQAMAAMEAIAQKL--PPGF--GFSWTGMSYEERLSgSQAPA 874
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 856 ILA-AIATVYIVLGVLYESYVHPLTILSTLPSAGVGALLALELFDAPFSLIALIGIMLLIGIVKKNAIMMVDFALDAQRN 934
Cdd:TIGR00915 875 LYAlSLLVVFLCLAALYESWSIPVSVMLVVPLGIIGALLATTLRGLSNDVYFQVGLLTTIGLSAKNAILIVEFAKELMAQ 954
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 935 GNlSPEEAIFQACLLRFRPIMMTTLAALFGALPLVISGGDGSELRQPLGITIVGGLVMSQLLTLYTTPVVYLFFDRLRLR 1014
Cdd:TIGR00915 955 GK-SIVEAALEAARLRLRPILMTSLAFILGVVPLAISTGAGSGSQHAIGTGVFGGMVTATVLAIFFVPLFYVVVRRLFKR 1033
|
1050
....*....|
gi 2526274827 1015 VARKNRTTVT 1024
Cdd:TIGR00915 1034 KAHEKEMSVE 1043
|
|
| CusA |
COG3696 |
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism]; |
10-1018 |
9.18e-153 |
|
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism];
Pssm-ID: 442911 [Multi-domain] Cd Length: 1031 Bit Score: 479.91 E-value: 9.18e-153
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 10 RPVATILISLAITLCGVLGFRLLPVAPLP-----QVdfpVIMVSAslPGASPETMASSVATPLERSLGRIAGVNEMTSSS 84
Cdd:COG3696 12 NRLLVLLLTLLLAAAGIYSLRRLPIDAFPditnvQV---QVITEA--PGLSPEEVEQQVTYPIETALNGLPGVKEVRSIS 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 85 SLGSTRIILEFSFDRDINGAARDVQAAINAAQSLLPSGmpsrptyrkANPSDAP-------IMILTLTSD--TYSQGQLY 155
Cdd:COG3696 87 RFGLSVVTVIFEDGTDIYWARQLVLERLQQVREQLPAG---------VTPELGPistglgeIYQYTLESDpgKYSLMELR 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 156 DFASTQLAQTISQINGVGDV-SVGGsslpAVR---VGLNPQALFNQGVSLDDVRSAISNANVRKPQGAIEDGSHRWQIHT 231
Cdd:COG3696 158 TLQDWVIRPQLRSVPGVAEVnSFGG----FVKqyqVLVDPAKLRAYGLTLDDVIEALERNNANVGGGYIERGGQEYLVRG 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 232 NDELKTAAEYQPLIIHYNNGAAVRLSDVASVTDSvQDVRN--AGMTNAKPAILLMIRKLPEANIIETVNSIRARLPELQQ 309
Cdd:COG3696 234 IGLIRSLEDIENIVVKTRNGTPVLLRDVAEVRIG-PAPRRgaATLNGEGEVVGGIVLMLKGENALEVIEAVKAKLAELKP 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 310 TIPAAIDLQIAQDRSPTIRASLEEVEQTLVISVALVILVVFLFLRSGRATLIPAVAVPVSLIGTFAAMYLCGFSLNNLSL 389
Cdd:COG3696 313 SLPEGVKIVPFYDRSDLIDRAIHTVTKNLLEGALLVILVLFLFLGNLRAALIVALAIPLSLLFAFIVMRLFGISANLMSL 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 390 MALTIATGFVVDDAIVVLENISRHLE------AGVNPLQAALQGTREVG----FTVLSMSLSLVAVFLplllmgglpgrl 459
Cdd:COG3696 393 GGLAIDFGIIVDGAVVMVENILRRLEenraagTPRERLEVVLEAAREVRrpifFATLIIILVFLPIFT------------ 460
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 460 lreF-----------AVTLSVAIGISLIISLTLTPMMCGWMLKRSKPHSQPrrkgfgRVLLAMQEGYGKSLKWVLNHTRL 528
Cdd:COG3696 461 ---LegvegklfrpmALTVIFALLGALLLSLTLVPVLASLLLRGKVPEKEN------PLVRWLKRLYRPLLRWALRHPKL 531
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 529 VGLVLIGTIVLNVWLYISIPKTFFPEQDTGVLMGGIQADQSISFQAMRGKLQDFMKIIREDKAVDNVTGFTGgsR----- 603
Cdd:COG3696 532 VLAVALVLLVLALALFPRLGSEFLPELDEGDLLVMATLPPGISLEESVELGQQVERILKSFPEVESVVSRTG--Raedat 609
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 604 ----VNSGMMFITLKPRGE--RNETAQQVIDRLRVKLAKEPGANL-FLMAVQDiRV-----GGRQANAsyqYTLLSDDLA 671
Cdd:COG3696 610 dpmgVNMSETFVILKPRSEwrSGRTKEELIAEMREALEQIPGVNFnFSQPIQM-RVdellsGVRADVA---VKIFGDDLD 685
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 672 ALREWEPKIRKALAALPQLADVNSDQQDNGAEMALTYDRETMSRLGINVEAANSLLNNAFGQREISTIYQPMNQYKVVME 751
Cdd:COG3696 686 VLRRLAEQIEAVLKTVPGAADVQVERVTGLPQLDIRIDRDAAARYGLNVADVQDVVETAIGGKAVGQVYEGERRFDIVVR 765
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 752 VDPRYTQDISALDKMFVINNDGKAIPLSYFASWQPANAPLSVNHQGLSAASTISFNL---PAGSSLSEASDAINRamtQL 828
Cdd:COG3696 766 LPEELRDDPEAIRNLPIPTPSGAQVPLSQVADIEVVEGPNQISRENGRRRIVVQANVrgrDLGSFVAEAQAKVAE---QV 842
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 829 GVPSTVRGSFAGTAQVFQETMNSQVILILAAIATVYIVLGVLYESYVHPLTILSTLPSAGVGALLALELFDAPFSLIALI 908
Cdd:COG3696 843 KLPPGYYIEWGGQFENLQRATARLAIVVPLALLLIFLLLYLAFGSVRDALLILLNVPFALIGGVLALWLRGMPLSVSAGV 922
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 909 GIMLLIGIVKKNAIMMVDFALDAQRNGnLSPEEAIFQACLLRFRPIMMTTLAALFGALPLVISGGDGSELRQPLGITIVG 988
Cdd:COG3696 923 GFIALFGVAVLNGVVLVSYINQLRAEG-LDLREAIIEGALERLRPVLMTALVAALGLLPMALSTGPGSEVQRPLATVVIG 1001
|
1050 1060 1070
....*....|....*....|....*....|
gi 2526274827 989 GLVMSQLLTLYTTPVVYLFFDRLRLRVARK 1018
Cdd:COG3696 1002 GLITSTLLTLLVLPALYLLFGRRRLRRAAA 1031
|
|
| PRK09579 |
PRK09579 |
multidrug efflux RND transporter permease subunit; |
1-1005 |
9.38e-140 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169983 [Multi-domain] Cd Length: 1017 Bit Score: 445.43 E-value: 9.38e-140
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 1 MKFFALFIYRPVATILISLAITLCGVLGFRLLPVAPLPQVDFPVIMVSASLPGASPETMASSVATPLERSLGRIAGVNEM 80
Cdd:PRK09579 1 MAFTDPFIRRPVLASVVSLLIVLLGFQAWSKLQIRQYPQMENALITVTTAYPGANAETIQGYITQPLQQSLASAEGIDYM 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 81 TSSSSLGSTRIILEFSFDRDINGAARDVQAAINAAQSLLPSGMPSrPTYRKANPSDAPIMILTLTSDTYSQGQLYDFAST 160
Cdd:PRK09579 81 TSVSRQNFSIISIYARIGADSDRLFTELLAKANEVKNQLPQDAED-PVLSKEAADASALMYISFYSEEMSNPQITDYLSR 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 161 QLAQTISQINGVGDVSVGGSSLPAVRVGLNPQALFNQGVSLDDVRSAISNANVRKPQGAIEDGSHRWQIHTNDELKTAAE 240
Cdd:PRK09579 160 VIQPKLATLPGMAEAEILGNQVFAMRLWLDPVKLAGFGLSAGDVTQAVRRYNFLSAAGEVKGEYVVTSINASTELKSAEA 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 241 YQPLIIHYNNGAAVRLSDVASVTDSVQDVRNAGMTNAKPAILLMIRKLPEANIIETVNSIRARLPELQQTIPAAIDLQIA 320
Cdd:PRK09579 240 FAAIPVKTSGDSRVLLGDVARVEMGAENYDSISSFDGIPSVYIGIKATPSANPLDVIKEVRAIMPELESQLPPNLKVSIA 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 321 QDRSPTIRASLEEVEQTLVISVALVILVVFLFLRSGRATLIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMALTIATGFVV 400
Cdd:PRK09579 320 YDATLFIQASIDEVVKTLGEAVLIVIVVVFLFLGALRSVLIPVVTIPLSMIGVLFFMQMMGYSINLLTLLAMVLAIGLVV 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 401 DDAIVVLENISRHLEAGVNPLQAALQGTREVGFTVLSMSLSLVAVFLPLLLMGGLPGRLLREFAVTLSVAIGISLIISLT 480
Cdd:PRK09579 400 DDAIVVVENIHRHIEEGKSPFDAALEGAREIAMPVVSMTITLAAVYAPIGFLTGLTGALFKEFALTLAGAVIISGIVALT 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 481 LTPMMCGWMLKRSK-PHSQPRRkgFGRVLLAMQEGYGKSLKWVLNhTRLVGLVLiGTIVLNVW--LYISIPKTFFPEQDT 557
Cdd:PRK09579 480 LSPMMCALLLRHEEnPSGLAHR--LDRLFERLKQRYQRALHGTLN-TRPVVLVF-AVIVLALIpvLLKFTQSELAPEEDQ 555
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 558 GVLMGGIQADQSISFQAMRGKLQDFMKIIR---EDKAVDNVTGFTGgsrVNSGMMFITLKPRGERNETAQQVIDRLRVKL 634
Cdd:PRK09579 556 GIIFMMSSSPQPANLDYLNAYTDEFTPIFKsfpEYYSSFQINGFNG---VQSGIGGFLLKPWNERERTQMELLPLVQAKL 632
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 635 AKEPGANLFLMAVQDIRVGGRqaNASYQYTL-LSDDLAALREWEPKIRKALAALPQLADVNSDQQDNGAEMALTYDRETM 713
Cdd:PRK09579 633 EEIPGLQIFGFNLPSLPGTGE--GLPFQFVInTANDYESLLQVAQRVKQRAQESGKFAFLDIDLAFDKPEVVVDIDRAKA 710
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 714 SRLGINVEAANSLLNNAFGQREISTIYQPMNQYKVVMEVDPRYTQDISALDKMFVINNDGKAIPLSYFASWQPANAPLSV 793
Cdd:PRK09579 711 AQMGVSMQDLGGTLATLLGEGEINRFTIDGRSYKVIAQVERPYRDNPGWLNNYYVKNEQGQLLPLSTLITLSDRARPRQL 790
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 794 NH-QGLSAASTISFNLpagSSLSEASDAInRAMTQLGVPSTVRGSFAGTAQVFQETMNSQVILILAAIATVYIVLGVLYE 872
Cdd:PRK09579 791 NQfQQLNSAIISGFPI---VSMGEAIETV-QQIAREEAPEGFAFDYAGASRQYVQEGSALWVTFGLALAIIFLVLAAQFE 866
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 873 SYVHPLTILSTLPSAGVGALLALELFDAPFSLIALIGIMLLIGIVKKNAIMMVDFALDAQRNGNLSPEEAIFQACLLRFR 952
Cdd:PRK09579 867 SFRDPLVILVTVPLSICGALIPLFLGVSSMNIYTQVGLVTLIGLISKHGILIVEFANQLRHEQGLSRREAIEEAAAIRLR 946
|
970 980 990 1000 1010
....*....|....*....|....*....|....*....|....*....|...
gi 2526274827 953 PIMMTTLAALFGALPLVISGGDGSELRQPLGITIVGGLVMSQLLTLYTTPVVY 1005
Cdd:PRK09579 947 PVLMTTAAMVFGMVPLILATGAGAVSRFDIGLVIATGMSIGTLFTLFVLPCIY 999
|
|
| PRK09577 |
PRK09577 |
multidrug efflux RND transporter permease subunit; |
7-1018 |
2.45e-137 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169981 [Multi-domain] Cd Length: 1032 Bit Score: 439.29 E-value: 2.45e-137
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 7 FIYRPVATILISLAITLCGVLGFRLLPVAPLPQVDFPVIMVSASLPGASPETMASSVATPLERSLGRIAGVNEMTSSSSL 86
Cdd:PRK09577 5 FIDRPVFAWVISLFIMLGGIFAIRALPVAQYPDIAPPVVSIYATYPGASAQVVEESVTALIEREMNGAPGLLYTSATSSA 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 87 GSTRIILEFSFDRDINGAARDVQAAINAAQSLLPSGMpSRPTYRKANPSDAPIMILTLTSDT--YSQGQLYDFASTQLAQ 164
Cdd:PRK09577 85 GQASLSLTFKQGVNADLAAVEVQNRLKTVEARLPEPV-RRDGIQVEKAADNIQLIVSLTSDDgrLTGVELGEYASANVLQ 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 165 TISQINGVGDVSVGGSSLpAVRVGLNPQALFNQGVSLDDVRSAISNANVRKPQGAI------EDGSHRWQIHTNDELKTA 238
Cdd:PRK09577 164 ALRRVEGVGKVQFWGAEY-AMRIWPDPVKLAALGLTASDIASAVRAHNARVTIGDIgrsavpDSAPIAATVFADAPLKTP 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 239 AEYQPLIIHYN-NGAAVRLSDVASVTDSVQDVRNAGMTNAKPAILLMIRKLPEANIIETVNSIRARLPELQQTIPAAIDL 317
Cdd:PRK09577 243 EDFGAIALRARaDGSALYLRDVARIEFGGNDYNYPSYVNGKTATGMGIKLAPGSNAVATEKRVRATMDELSRYFPPGVKY 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 318 QIAQDRSPTIRASLEEVEQTLVISVALVILVVFLFLRSGRATLIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMALTIATG 397
Cdd:PRK09577 323 QIPYETSSFVRVSMNKVVTTLIEAGVLVFLVMFLFMQNFRATLIPTLVVPVALLGTFGVMLAAGFSINVLTMFGMVLAIG 402
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 398 FVVDDAIVVLENISRHL-EAGVNPLQAALQGTREVGFTVLSMSLSLVAVFLPLLLMGGLPGRLLREFAVTLSVAIGISLI 476
Cdd:PRK09577 403 ILVDDAIVVVENVERLMvEEGLSPYDATVKAMKQISGAIVGITVVLTSVFVPMAFFGGAVGNIYRQFALSLAVSIGFSAF 482
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 477 ISLTLTPMMCGWMLKRSKPHSQPRRKGFG---RVLLAMQEGYGKSLKWVLNHTrLVGLVLIGTIV-LNVWLYISIPKTFF 552
Cdd:PRK09577 483 LALSLTPALCATLLKPVDGDHHEKRGFFGwfnRFVARSTQRYATRVGAILKRP-LRWLVVYGALTaAAALLFTRLPTAFL 561
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 553 PEQDTGVLMGGIQADQSISFQAMRGKLQDFMKIIREDKAVDNVTGFTG----GSRVNSGMMFITLKPRGERNETAQQV-- 626
Cdd:PRK09577 562 PDEDQGNFMVMVIRPQGTPLAETMQSVREVESYLRRHEPVAYTFALGGfnlyGEGPNGGMIFVTLKDWKERKAARDHVqa 641
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 627 -IDRLRVKLAKEPGANLFLMAVQ-----------DIRVGGRqANASYQytllsdDLAALREwepKIRKALAALPQLADVN 694
Cdd:PRK09577 642 iVARINERFAGTPNTTVFAMNSPalpdlgstsgfDFRLQDR-GGLGYA------AFVAARE---QLLAEGAKDPALTDLM 711
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 695 SDQQDNGAEMALTYDRETMSRLGINVEAANSLLNNAFGQREISTIYQPMNQYKVVMEVDPRYTQDISALDKMFVINNDGK 774
Cdd:PRK09577 712 FAGTQDAPQLKLDIDRAKASALGVSMDEINTTLAVMFGSDYIGDFMHGSQVRRVIVQADGRHRLDPDDVKKLRVRNAQGE 791
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 775 AIPLSYFASWQPANAPLSVNHQGLSAASTISFNLPAGSSLSEASDAINRAMTQLgvPSTVrgSFAGTAQVFQETMN-SQV 853
Cdd:PRK09577 792 MVPLAAFATLHWTLGPPQLTRYNGYPSFTINGSAAPGHSSGEAMAAIERIAATL--PAGI--GYAWSGQSFEERLSgAQA 867
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 854 ILILA-AIATVYIVLGVLYESYVHPLTILSTLPSAGVGALLALELFDAPFSLIALIGIMLLIGIVKKNAIMMVDFALDAQ 932
Cdd:PRK09577 868 PMLFAlSVLVVFLALAALYESWSIPFAVMLVVPLGVIGAVLGVTLRGMPNDIYFKVGLIATIGLSAKNAILIVEVAKDLV 947
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 933 RNGnLSPEEAIFQACLLRFRPIMMTTLAALFGALPLVISGGDGSELRQPLGITIVGGLVMSQLLTLYTTPVVYLFFDRLR 1012
Cdd:PRK09577 948 AQR-MSLADAALEAARLRLRPIVMTSLAFGVGVLPLAFASGAASGAQIAIGTGVLGGVITATVLAVFLVPLFFVVVGRLF 1026
|
....*.
gi 2526274827 1013 LRVARK 1018
Cdd:PRK09577 1027 DVGPRR 1032
|
|
| PRK10555 |
PRK10555 |
multidrug efflux RND transporter permease AcrD; |
7-1022 |
1.72e-125 |
|
multidrug efflux RND transporter permease AcrD;
Pssm-ID: 182544 [Multi-domain] Cd Length: 1037 Bit Score: 407.68 E-value: 1.72e-125
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 7 FIYRPVATILISLAITLCGVLGFRLLPVAPLPQVDFPVIMVSASLPGASPETMASSVATPLERSLGRIAGVNEMTS-SSS 85
Cdd:PRK10555 5 FIDRPIFAWVLAILLCLTGTLAIFSLPVEQYPDLAPPNVRITANYPGASAQTLENTVTQVIEQNMTGLDNLMYMSSqSSG 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 86 LGSTRIILEFSFDRDINGAARDVQAAINAAQSLLPSGMPSRP-TYRKANPSDAPIMILTLTSDTYSQGQLYDFASTQLAQ 164
Cdd:PRK10555 85 TGQASVTLSFKAGTDPDEAVQQVQNQLQSAMRKLPQAVQNQGvTVRKTGDTNILTIAFVSTDGSMDKQDIADYVASNIQD 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 165 TISQINGVGDVSVGGSSLpAVRVGLNPQALFNQGVSLDDVRSAISNANVRKPQG------AIEDGSHRWQIHTNDELKTA 238
Cdd:PRK10555 165 PLSRVNGVGDIDAYGSQY-SMRIWLDPAKLNSFQMTTKDVTDAIESQNAQIAVGqlggtpSVDKQALNATINAQSLLQTP 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 239 AEYQPLIIHYN-NGAAVRLSDVASVTDSVQDVRNAGMTNAKPAILLMIRKLPEANIIETVNSIRARLPELQQTIPAAIDL 317
Cdd:PRK10555 244 EQFRDITLRVNqDGSEVTLGDVATVELGAEKYDYLSRFNGKPASGLGVKLASGANEMATAKLVLNRLDELAQYFPHGLEY 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 318 QIAQDRSPTIRASLEEVEQTLVISVALVILVVFLFLRSGRATLIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMALTIATG 397
Cdd:PRK10555 324 KVAYETTSFVKASIEDVVKTLLEAIALVFLVMYLFLQNFRATLIPTIAVPVVLMGTFSVLYAFGYSINTLTMFAMVLAIG 403
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 398 FVVDDAIVVLENISRHL-EAGVNPLQAALQGTREVGFTVLSMSLSLVAVFLPLLLMGGLPGRLLREFAVTLSVAIGISLI 476
Cdd:PRK10555 404 LLVDDAIVVVENVERIMsEEGLTPREATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGTTGAIYRQFSITIVSAMVLSVL 483
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 477 ISLTLTPMMCGWMLKRSKPHSQPRRKG--------FGRVLLAMQEGYGK----SLKWVlnhtrLVGLVLIGTIvlnVWLY 544
Cdd:PRK10555 484 VAMILTPALCATLLKPLKKGEHHGQKGffgwfnrmFNRNAERYEKGVAKilhrSLRWI-----LIYVLLLGGM---VFLF 555
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 545 ISIPKTFFPEQDTGVLMGGIQADQSISfqamrgkLQDFMKIIRE------DKAVDNVTGF-------TGGSRVNSGMMFI 611
Cdd:PRK10555 556 LRLPTSFLPLEDRGMFTTSVQLPSGST-------QQQTLKVVEKvekyyfTHEKDNVMSVfatvgsgPGGNGQNVARMFI 628
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 612 TLKPRGER---NETAQQVIDRLRVKLAKEPGANLFlmAVQDIRVGGRQANASYQYTLLS------DDLAALREwepKIRK 682
Cdd:PRK10555 629 RLKDWDERdskTGTSFAIIERATKAFNKIKEARVI--ASSPPAISGLGSSAGFDMELQDhagaghDALMAARN---QLLA 703
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 683 ALAALPQLADVNSDQQDNGAEMALTYDRETMSRLGINVEAANSLLNNAFGQREISTIYQPMNQYKVVMEVDPRYTQDISA 762
Cdd:PRK10555 704 LAAKNPELTRVRHNGLDDSPQLQIDIDQRKAQALGVSIDDINDTLQTAWGSSYVNDFMDRGRVKKVYVQAAAPYRMLPDD 783
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 763 LDKMFVINNDGKAIPLSYFAS--WQpANAPLSVNHQGLSAASTISFNLPaGSSLSEASDAINRAMTQLgvPSTVrgSFAG 840
Cdd:PRK10555 784 INLWYVRNKDGGMVPFSAFATsrWE-TGSPRLERYNGYSAVEIVGEAAP-GVSTGTAMDIMESLVKQL--PNGF--GLEW 857
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 841 TAQVFQETMNSQVILILAAIA--TVYIVLGVLYESYVHPLTILSTLPSAGVGALLALELFDAPFSLIALIGIMLLIGIVK 918
Cdd:PRK10555 858 TAMSYQERLSGAQAPALYAISllVVFLCLAALYESWSVPFSVMLVVPLGVIGALLATWMRGLENDVYFQVGLLTVIGLSA 937
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 919 KNAIMMVDFALDAQRNGNlSPEEAIFQACLLRFRPIMMTTLAALFGALPLVISGGDGSELRQPLGITIVGGLVMSQLLTL 998
Cdd:PRK10555 938 KNAILIVEFANEMNQKGH-DLFEATLHASRQRLRPILMTSLAFIFGVLPMATSTGAGSGSQHAVGTGVMGGMISATILAI 1016
|
1050 1060
....*....|....*....|....
gi 2526274827 999 YTTPvvyLFFDRLRLRVARKNRTT 1022
Cdd:PRK10555 1017 FFVP---LFFVLVRRRFPLKPRPE 1037
|
|
| PRK15127 |
PRK15127 |
multidrug efflux RND transporter permease subunit AcrB; |
6-1019 |
4.31e-123 |
|
multidrug efflux RND transporter permease subunit AcrB;
Pssm-ID: 185081 [Multi-domain] Cd Length: 1049 Bit Score: 401.59 E-value: 4.31e-123
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 6 LFIYRPVATILISLAITLCGVLGFRLLPVAPLPQVDFPVIMVSASLPGASPETMASSVATPLERSLGRIAGVNEMTSSS- 84
Cdd:PRK15127 4 FFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSSNSd 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 85 SLGSTRIILEFSFDRDINGAARDVQAAINAAQSLLPSGMPSRP-TYRKANPSDAPIMILTLTSDTYSQGQLYDFASTQLA 163
Cdd:PRK15127 84 STGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQEVQQQGvSVEKSSSSFLMVVGVINTDGTMTQEDISDYVAANMK 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 164 QTISQINGVGDVSVGGSSLpAVRVGLNPQALFNQGVSLDDVRSAISNANVRKPQGA------IEDGSHRWQIHTNDELKT 237
Cdd:PRK15127 164 DPISRTSGVGDVQLFGSQY-AMRIWMNPNELNKFQLTPVDVINAIKAQNAQVAAGQlggtppVKGQQLNASIIAQTRLTS 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 238 AAEYQPLIIHYN-NGAAVRLSDVASVTDSVQDVRNAGMTNAKPAILLMIRKLPEANIIETVNSIRARLPELQQTIPAAID 316
Cdd:PRK15127 243 TEEFGKILLKVNqDGSRVRLRDVAKIELGGENYDIIAEFNGQPASGLGIKLATGANALDTAAAIRAELAKMEPFFPSGLK 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 317 LQIAQDRSPTIRASLEEVEQTLVISVALVILVVFLFLRSGRATLIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMALTIAT 396
Cdd:PRK15127 323 IVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVLAI 402
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 397 GFVVDDAIVVLENISRHL-EAGVNPLQAALQGTREVGFTVLSMSLSLVAVFLPLLLMGGLPGRLLREFAVTLSVAIGISL 475
Cdd:PRK15127 403 GLLVDDAIVVVENVERVMaEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMALSV 482
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 476 IISLTLTPMMCGWMLKR-SKPHSQPRRKG----FGRVLLAMQEGYGKSLKWVLNHTRLVGLVLIGTIVLNVWLYISIPKT 550
Cdd:PRK15127 483 LVALILTPALCATMLKPiAKGDHGEGKKGffgwFNRMFEKSTHHYTDSVGNILRSTGRYLVLYLIIVVGMAYLFVRLPSS 562
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 551 FFPEQDTGVLMGGIQADQSISfQAMRGKLQDFMKIIREDKAVDNVT--------GFTGGSRvNSGMMFITLKPRGERNET 622
Cdd:PRK15127 563 FLPDEDQGVFLTMVQLPAGAT-QERTQKVLNEVTDYYLTKEKNNVEsvfavngfGFAGRGQ-NTGIAFVSLKDWADRPGE 640
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 623 AQQV---IDRLRVKLAKEPGANLFLMAVQDIRVGGRQANASYQYT----LLSDDLAALREwepkirKALAALPQLADVNS 695
Cdd:PRK15127 641 ENKVeaiTMRATRAFSQIKDAMVFAFNLPAIVELGTATGFDFELIdqagLGHEKLTQARN------QLLGEAAKHPDMLV 714
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 696 DQQDNGAE----MALTYDRETMSRLGINVEAANSLLNNAFGQREISTIYQPMNQYKVVMEVDPRYTQDISALDKMFVINN 771
Cdd:PRK15127 715 GVRPNGLEdtpqFKIDIDQEKAQALGVSISDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLPDDIGDWYVRAA 794
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 772 DGKAIPLSYFAS--WQpANAPLSVNHQGLSAASTISFNLPaGSSLSEASDAINRAMTQLgvPSTVrgSFAGTAQVFQETM 849
Cdd:PRK15127 795 DGQMVPFSAFSSsrWE-YGSPRLERYNGLPSMEILGQAAP-GKSTGEAMELMEELASKL--PTGV--GYDWTGMSYQERL 868
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 850 NSQVILILAAIA--TVYIVLGVLYESYVHPLTILSTLPSAGVGALLALELFDAPFSLIALIGIMLLIGIVKKNAIMMVDF 927
Cdd:PRK15127 869 SGNQAPALYAISliVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEF 948
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 928 ALDAQRNGNLSPEEAIFQACLLRFRPIMMTTLAALFGALPLVISGGDGSELRQPLGITIVGGLVMSQLLTLYTTPVvylF 1007
Cdd:PRK15127 949 AKDLMDKEGKGLIEATLEAVRMRLRPILMTSLAFILGVMPLVISSGAGSGAQNAVGTGVMGGMVTATVLAIFFVPV---F 1025
|
1050
....*....|..
gi 2526274827 1008 FDRLRLRVARKN 1019
Cdd:PRK15127 1026 FVVVRRRFSRKN 1037
|
|
| 2A0601 |
TIGR00914 |
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation ... |
15-1015 |
7.58e-85 |
|
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation antiporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Detoxification, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 129992 [Multi-domain] Cd Length: 1051 Bit Score: 296.29 E-value: 7.58e-85
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 15 ILISLAITLCGVLGFRLLPVAPLPQVDFPVIMVSASLPGASPETMASSVATPLERSLGRIAGVNEMTSSSSLGSTRIILE 94
Cdd:TIGR00914 17 LLATLVMAILGIWSYNRLPIDAVPDITNVQVQINTSAPGYSPLEVEQRVTYPIETAMAGLPGLETTRSLSRYGLSQVTVI 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 95 FSFDRDINGAARDVQAAINAAQSLLPSGMpsRPTYRKANPSDAPIMILTLTSD---TYSQGQLYDFASTQLAQ------T 165
Cdd:TIGR00914 97 FKDGTDLYFARQLVNERLQQARDNLPEGV--SPEMGPISTGLGEIFLYTVEAEegaRKKDGGAYTLTDLRTIQdwiirpQ 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 166 ISQINGVGDVSVGGSSLPAVRVGLNPQALFNQGVSLDDVRSAISNANVRKPQGAIEDGSHRWQIHTNDELKTAAEYQPLI 245
Cdd:TIGR00914 175 LRTVPGVAEVNSIGGYVKQFLVAPDPEKLAAYGLSLADVVNALERNNQNVGAGYIERRGEQYLVRAPGQVQSMDDIRNIV 254
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 246 IHYNNGAAVRLSDVASVTDSVQDVRNAGMTNAKPAILLMIRKLPEANIIETVNSIRARLPELQQTIPAAIDLQIAQDRSP 325
Cdd:TIGR00914 255 IATGEGVPIRIRDVARVQIGKELRTGAATENGKEVVLGTVFMLIGENSRTVAQAVGDKLETINKTLPEGVEIVTTYDRSQ 334
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 326 TIRASLEEVEQTLVISVALVILVVFLFLRSGRATLIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMALtiATGFVVDDAIV 405
Cdd:TIGR00914 335 LVDAAIATVKKNLLEGALLVIVILFLFLGNIRAALIAATVIPLSLLITFIGMVFQGISANLMSLGAL--DFGLIVDGAVV 412
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 406 VLENISRHLEAG----------VNPLQAALQGTREVGFTVLSMSLSLVAVFLPLLLMGGLPGRLLREFAVTLSVAIGISL 475
Cdd:TIGR00914 413 IVENAHRRLAEAqhhhgrqltlKERLHEVFAASREVRRPLIFGQLIITLVFLPIFTLTGVEGKMFHPMAFTVVLALAGAM 492
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 476 IISLTLTPMMCGWMLKRSKPHSQprrkgfGRVLLAMQEGYGKSLKWVLNHTRLVGLVLIGTIVLNVWLYISIPKTFFPEQ 555
Cdd:TIGR00914 493 ILSLTFVPAAVALFIRGKVAEKE------NRLMRVLKRRYEPLLERVLAWPAVVLGAAAVSIVLVVWIASRVGGEFIPSL 566
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 556 DTGVL------MGGIQADQSISFQamrgklQDFMKIIREDKAVDNVTGFTGGSRVNSGMM-------FITLKPRGERNE- 621
Cdd:TIGR00914 567 NEGDLayqalrIPGTSLAQSVAMQ------QTLEKLIKSFPEVARVFAKTGTAEIATDPMppnasdtYIILKPESQWPEg 640
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 622 --TAQQVIDRLRVKLAKEPG-ANLFLMAVQ---DIRVGGRQANASYQytLLSDDLAALREWEPKIRKALAALPQLADVNS 695
Cdd:TIGR00914 641 kkTKEDLIEEIQEATVRIPGnNYEFTQPIQmrfNELISGVRSDVAVK--VFGDDLDDLDATAEKISAVLKGVPGAADVKV 718
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 696 DQQDNGAEMALTYDRETMSRLGINVEAANSLLNNAFGQREISTIYQPMNQYKVVMEVDPRYTQDISALDKMFVI---NND 772
Cdd:TIGR00914 719 EQTTGLPYLTVEIDREKAARYGLTVGDVQDTVATAVGGRMSGETFEGDRRFDIVIRLPESLRESPQALRQLPIPlplSED 798
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 773 GK--AIPLSYFASWQPANAPLSVNHQGLSAASTISFNLPAGSSLSEASDAINRAMTQLGVPSTVRGSFAGTAQVFQETMN 850
Cdd:TIGR00914 799 ARkqFIPLSDVADLRVSPGPNQISRENGKRRVVVSANVRGRDLGSFVDDAKKAIAEQVKLPPGYWITWGGQFEQLQSATK 878
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 851 SQVILILAAIATVYIVLGVLYESYVHPLTILSTLPSAGVGALLALELFDAPFSLIALIGIMLLIGIVKKNAIMMVDFaLD 930
Cdd:TIGR00914 879 RLQIVVPVTLLLIFVLLYAAFGNVKDALLVFTGIPFALTGGVFALWLRGIPLSISAAVGFIALSGVAVLNGLVMISF-IR 957
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 931 AQRNGNLSPEEAIFQACLLRFRPIMMTTLAALFGALPLVISGGDGSELRQPLGITIVGGLVMSQLLTLYTTPVVYLFFDR 1010
Cdd:TIGR00914 958 KLLEEGPSLDEAVYEGALTRVRPVLMTALVASLGFVPMAIATGTGAEVQRPLATVVIGGIITATLLTLFVLPALYRLVHR 1037
|
....*
gi 2526274827 1011 LRLRV 1015
Cdd:TIGR00914 1038 RRHKG 1042
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
327-1016 |
4.18e-24 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 109.18 E-value: 4.18e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 327 IRASLEEVEQTLVISVALVILVVFLFLRSGRATLIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMALTIATGFVVDDAIVV 406
Cdd:COG1033 213 AEAIQSDLAIFFPLALLLILLLLFLFFRSLRGVLLPLLVVLLAVIWTLGLMGLLGIPLSPLTILVPPLLLAIGIDYGIHL 292
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 407 LENISRHLEAGVNPLQAALQGTREVGFTVLSMSLSLVAVFlplLLMGGLPGRLLREFAVTLSVAIGISLIISLTLTPMMC 486
Cdd:COG1033 293 LNRYREERRKGLDKREALREALRKLGPPVLLTSLTTAIGF---LSLLFSDIPPIRDFGIVAAIGVLLAFLTSLTLLPALL 369
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 487 GWMLKRSKPHSQPRRKGFGRVLLAmqegygKSLKWVLNHTRlvgLVLIGTIVLNVWLYISIPKTffpeqdtgvlmggiqa 566
Cdd:COG1033 370 SLLPRPKPKTRRLKKPPELGRLLA------KLARFVLRRPK---VILVVALVLAVVSLYGISRL---------------- 424
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 567 dqSISFQaMRGKLQDFMKIIREDKAVDNVtgFTGGSRVNsgMMFITLKPRGERNETAQQVIDRLRVKLAKEPGanlflma 646
Cdd:COG1033 425 --KVEYD-FEDYLPEDSPIRQDLDFIEEN--FGGSDPLE--VVVDTGEPDGLKDPEVLKEIDRLQDYLESLPE------- 490
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 647 vqdirvggrqanasyqytllsddlaalrewepkIRKALAalpqLADVnsdqqdngaemaltydretmsrlginVEAANSL 726
Cdd:COG1033 491 ---------------------------------VGKVLS----LADL--------------------------VKELNQA 507
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 727 LNNafGQREISTIyqPMNQYKVVMEVDPRYTQDISALDKMfvINNDGKAIPLSYFASWQPANAplsvnhqglsaastisf 806
Cdd:COG1033 508 LNE--GDPKYYAL--PESRELLAQLLLLLSSPPGDDLSRF--VDEDYSAARVTVRLKDLDSEE----------------- 564
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 807 nlpagssLSEASDAINRAMTQLGVPSTVRGSFAGTAQVFQETMN----SQVILILAAIATVYIVLGVLYESYVHPLTIL- 881
Cdd:COG1033 565 -------IKALVEEVRAFLAENFPPDGVEVTLTGSAVLFAAINEsvieSQIRSLLLALLLIFLLLLLAFRSLRLGLISLi 637
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 882 -STLPSAGVGALLAleLFDAPFSLIALIGIMLLIGIVKKNAIMMVDFALDAQRNGnLSPEEAIFQACLLRFRPIMMTTLA 960
Cdd:COG1033 638 pNLLPILLTFGLMG--LLGIPLNIATAVVASIALGIGVDYTIHFLSRYREERRKG-GDLEEAIRRALRTTGKAILFTSLT 714
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....*.
gi 2526274827 961 ALFGALPLVISGGDGseLRQpLGITIVGGLVMSQLLTLYTTPVVYLFFDRLRLRVA 1016
Cdd:COG1033 715 LAAGFGVLLFSSFPP--LAD-FGLLLALGLLVALLAALLLLPALLLLLDPRIAKKR 767
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
793-1020 |
6.42e-09 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 59.87 E-value: 6.42e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 793 VNHQGLSAASTISFNLPAGSSLSEASDAINRAMTQL------GVPSTVRGSFAGTAQVFQETMNSQVILILAAIATVYIV 866
Cdd:COG1033 155 VSPDGKATLIVVTLDPDPLSSDLDRKEVVAEIRAIIakyedpGVEVYLTGFPVLRGDIAEAIQSDLAIFFPLALLLILLL 234
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 867 LGVLYESyvhPLTILSTLPSAGVGALLAL---ELFDAPFSLIALIGIMLLIGIVKKNAIMMVDFALDAQRNGnLSPEEAI 943
Cdd:COG1033 235 LFLFFRS---LRGVLLPLLVVLLAVIWTLglmGLLGIPLSPLTILVPPLLLAIGIDYGIHLLNRYREERRKG-LDKREAL 310
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2526274827 944 FQACLLRFRPIMMTTLAALFGALPLVISGgdgSELRQPLGITIVGGLVMSQLLTLYTTPVVYLFFDRLRLRVARKNR 1020
Cdd:COG1033 311 REALRKLGPPVLLTSLTTAIGFLSLLFSD---IPPIRDFGIVAAIGVLLAFLTSLTLLPALLSLLPRPKPKTRRLKK 384
|
|
| 2A067 |
TIGR00921 |
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ... |
820-1019 |
3.82e-08 |
|
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273340 [Multi-domain] Cd Length: 719 Bit Score: 57.54 E-value: 3.82e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 820 AINRAMTQLGVPSTVRGSFAGTAQVFQETMNSQVILILAAIATVYIVLGVLYESYVHPLTILSTLPSAGVGALLALELFD 899
Cdd:TIGR00921 163 SLERTNPPSGKFLDVTGSPAINYDIEREFGKDMGTTMAISGILVVLVLLLDFKRWWRPLLPLVIILFGVAWVLGIMGWLG 242
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 900 APFSLIALIGIMLLIGIVKKNAIMMVDFALDAQRNGNlSPEEAIFQACLLRFRPIMMTTLAALFGALPLVISggdGSELR 979
Cdd:TIGR00921 243 IPLYATTLLAVPMLIGVGIDYGIQTLNRYEEERDIGR-AKGEAIVTAVRRTGRAVLIALLTTSAGFAALALS---EFPMV 318
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 2526274827 980 QPLGITIVGGLVMSQLLTLYTTPVVYLFFDRLRLRVARKN 1019
Cdd:TIGR00921 319 SEFGLGLVAGLITAYLLTLLVLPALLQSIDIGREKVKKEI 358
|
|
| YdfJ |
COG2409 |
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function ... |
295-631 |
8.40e-08 |
|
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function prediction only];
Pssm-ID: 441964 [Multi-domain] Cd Length: 697 Bit Score: 56.31 E-value: 8.40e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 295 ETVNSIRARLPELQQ-------TIPAAIDLQIAQdrsptirASLEEVEQTLVISVALVILVVFLFLRSGRATLIPAVAVP 367
Cdd:COG2409 132 EAVDALRDAVAAAPApgltvyvTGPAALAADLNE-------AFEEDLGRAELITLPVALVVLLLVFRSLVAALLPLLTAG 204
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 368 VSLIGTFAAMYLCGFSLnNLSLMALTIATGFV----VDDAIVVlenISRH---LEAGVNPLQA---ALQGTREV----GF 433
Cdd:COG2409 205 LAVGVALGLLALLAAFT-DVSSFAPNLLTMLGlgvgIDYALFL---VSRYreeLRAGEDREEAvarAVATAGRAvlfsGL 280
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 434 TV----LSMSLSLVAVFlplllmgglpgrllREFAVTLSVAIGISLIISLTLTPMMCGWMLKRSKPhsqPRRKGFGRVLL 509
Cdd:COG2409 281 TVaialLGLLLAGLPFL--------------RSMGPAAAIGVAVAVLAALTLLPALLALLGRRVFW---PRRPRRRRAAA 343
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 510 AMQEGYGKSLKWVLNHTRLV------GLVLIGTIVLNVWLYISIPKTF----------------FPEQDTGVLMGGIQAD 567
Cdd:COG2409 344 PESGFWRRLARAVVRRPVPVlvaavaVLLALALPALGLRLGLPDADSLpadspsrqgydalaehFPPGSNGPLTVVVESD 423
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2526274827 568 QSISfQAMRGKLQDFMKIIREDKAVDNVTGFTGGSRVNSGMMFITLKPRGE-RNETAQQVIDRLR 631
Cdd:COG2409 424 DDLD-PADLAALDALAAALAAVPGVASVQPPTRPEGTDGDAARLQVVPDGDpDSPEAIDLVDRLR 487
|
|
| 2A067 |
TIGR00921 |
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ... |
224-483 |
9.77e-08 |
|
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273340 [Multi-domain] Cd Length: 719 Bit Score: 56.00 E-value: 9.77e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 224 SHRWQIHTNDELKTAAEYQPLIIHYNN-------GAAVRLSDVASVTDSVQDVRNAG---------------MTNAKPAI 281
Cdd:TIGR00921 41 SYKWYHVLQREFGTSTKTLLVVIEGDDvtrkpvlDYMRRLEQRLREKPYVTNVRSAAdimrqipgnfplpvtMPEVRPLM 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 282 LLMIRKLpEANII--ETVNSIRARL---PELQQTIPAAIDLQIAQDR-------------SPTIRASLEEVEQ-----TL 338
Cdd:TIGR00921 121 SEYPRSK-EMFLSkdHTVAIIIVQLksdADYKQVVPIYNDVERSLERtnppsgkfldvtgSPAINYDIEREFGkdmgtTM 199
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 339 VISVALVILVVFLFLRSGRATLIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMALTIATGFVVDDAIVVLENISRHLEAGV 418
Cdd:TIGR00921 200 AISGILVVLVLLLDFKRWWRPLLPLVIILFGVAWVLGIMGWLGIPLYATTLLAVPMLIGVGIDYGIQTLNRYEEERDIGR 279
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2526274827 419 NPLQAALQGTREVGFTVLSMSLSLVAVFlplLLMGGLPGRLLREFAVTLSVAIGISLIISLTLTP 483
Cdd:TIGR00921 280 AKGEAIVTAVRRTGRAVLIALLTTSAGF---AALALSEFPMVSEFGLGLVAGLITAYLLTLLVLP 341
|
|
| PRK13023 |
PRK13023 |
protein translocase subunit SecDF; |
292-502 |
1.47e-06 |
|
protein translocase subunit SecDF;
Pssm-ID: 171842 [Multi-domain] Cd Length: 758 Bit Score: 52.31 E-value: 1.47e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 292 NIIETVNSIRARLPELQQTIPAAIDLQIAQDRSPTIRASL------------------EEVEQTLVISVALVILVV--FL 351
Cdd:PRK13023 216 NQVVSAPTVSGPLDTSELQIEGAFDLQAANNMAVVLRSGAlpqavtvleertiasalgEDYASAAVLAALLAALVVglFM 295
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 352 FLRSGRATLIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMALTIATGFVVDDAIVVLENISRHLEAGVNPLQAALQGTREV 431
Cdd:PRK13023 296 VLSYGILGVIALVALVVNIIILTAVLSLIGASISLASIAGLVLTIGLAVDAHILIYERVREDRRKGYSVVQAMESGFYRA 375
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2526274827 432 GFTVLSMSLSlvaVFLPLLLMGGLPGRLLREFAVTLSVAIGISLIISLTLTPMMCGWMLKRSKPHSQPRRK 502
Cdd:PRK13023 376 LSTIVDANLT---TLIAALVLFLLGSGTVHGFALTVAIGIGTTLFTTLTFTRLLIAQWVRTAKPKEVPKRR 443
|
|
| MMPL |
pfam03176 |
MMPL family; Members of this family are putative integral membrane proteins from bacteria. ... |
786-1022 |
3.73e-04 |
|
MMPL family; Members of this family are putative integral membrane proteins from bacteria. Several of the members are mycobacterial proteins. Many of the proteins contain two copies of this aligned region. The function of these proteins is not known, although it has been suggested that they may be involved in lipid transport.
Pssm-ID: 308676 [Multi-domain] Cd Length: 332 Bit Score: 43.82 E-value: 3.73e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 786 PANAPLSVNHQGLSAASTISFNLPAGSSLSEAS-DAINRAMTQLGVPSTVRGSFAGTAQVFQETMNSQ----VILILAAI 860
Cdd:pfam03176 73 PDTAALFVSPDGKAAYVVVTLEGDPGTTEADESvAAVRDAVEQAPPPEGLKAYLTGPAATVADLRDAGdrdlGLIEAVTL 152
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 861 ATVYIVLGVLYESYVHPLTILST-----LPSAGVGALLALELFDAPFSLIALIGIMLLIGIVKKNAIMMVDFALDAQRNG 935
Cdd:pfam03176 153 VVIFIILLIVYRSVVAALLPLLTvglslGAAQGLVAILAHILGIGLSTFALNLLVVLLIAVGTDYALFLVSRYREELRAG 232
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 936 nLSPEEAIFQAcllrfrpiMMTTLAALFGAlPLVISGGDG----SELR--QPLGITIVGGLVMSQLLTLYTTPVVYLFFD 1009
Cdd:pfam03176 233 -EDREEAVIRA--------VRGTGKVVTAA-GLTVAIAMLalsfARLPvfAQVGPTIAIGVLVDVLAALTLLPALLALLG 302
|
250
....*....|...
gi 2526274827 1010 RLRLRVARKNRTT 1022
Cdd:pfam03176 303 RWGLWPPKRDRTA 315
|
|
| MMPL |
pfam03176 |
MMPL family; Members of this family are putative integral membrane proteins from bacteria. ... |
312-501 |
3.93e-04 |
|
MMPL family; Members of this family are putative integral membrane proteins from bacteria. Several of the members are mycobacterial proteins. Many of the proteins contain two copies of this aligned region. The function of these proteins is not known, although it has been suggested that they may be involved in lipid transport.
Pssm-ID: 308676 [Multi-domain] Cd Length: 332 Bit Score: 43.82 E-value: 3.93e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 312 PAAI--DLQIAQDRSPTIrasleeveqTLVISVALVILVVFLFLRSGRATLIPAVAVPVSLIGTFAAM----YLCGFSLN 385
Cdd:pfam03176 129 PAATvaDLRDAGDRDLGL---------IEAVTLVVIFIILLIVYRSVVAALLPLLTVGLSLGAAQGLVailaHILGIGLS 199
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 386 NLS---LMALTIATGfvVDDAIVVlenISRHLE---AGVNPLQAALQGTREVG-----------FTVLSMSLSLVAVFlp 448
Cdd:pfam03176 200 TFAlnlLVVLLIAVG--TDYALFL---VSRYREelrAGEDREEAVIRAVRGTGkvvtaagltvaIAMLALSFARLPVF-- 272
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 2526274827 449 lllmgglpgrllREFAVTLSVAIGISLIISLTLTPMMCG----WMLKRSKPHSQPRR 501
Cdd:pfam03176 273 ------------AQVGPTIAIGVLVDVLAALTLLPALLAllgrWGLWPPKRDRTARW 317
|
|
| SecD |
COG0342 |
Preprotein translocase subunit SecD [Intracellular trafficking, secretion, and vesicular ... |
314-497 |
5.41e-04 |
|
Preprotein translocase subunit SecD [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440111 [Multi-domain] Cd Length: 434 Bit Score: 43.57 E-value: 5.41e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 314 AIDLQIAQDR--SPT-----IRASLeeveQTLVISVALVILVVFLFLRsgratlIPAVAVPVSLIG----TFAAMYLCGF 382
Cdd:COG0342 250 PAPLEIVEERtvGPTlgadsIEKGL----IAGLIGLLLVALFMLLYYR------LPGLVANIALALnvvlLLGVLSLLGA 319
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 383 slnNLSL-----MALTIATGfvVDDAIVVLENISRHLEAGvNPLQAALqgtrEVGF-------------TVLSMS----L 440
Cdd:COG0342 320 ---TLTLpgiagIILTIGMA--VDANVLIFERIREELRAG-RSLRAAI----EAGFkrafstildanvtTLIAAVvlfvL 389
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 2526274827 441 SLVAVflplllmgglpgrllREFAVTLSVAIGISLIISLTLTPMMCGWMLKRSKPHS 497
Cdd:COG0342 390 GTGPV---------------KGFAVTLILGILISMFTAVPVTRPLLNLLLGRRRLKK 431
|
|
| PRK14726 |
PRK14726 |
protein translocase subunit SecDF; |
342-500 |
5.99e-04 |
|
protein translocase subunit SecDF;
Pssm-ID: 237805 [Multi-domain] Cd Length: 855 Bit Score: 43.94 E-value: 5.99e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 342 VALVILVVFLFLRSGRATLIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMALTIATGFVVDDAIVVLENISRHLEAGVNPL 421
Cdd:PRK14726 380 IAAILVAALMIGFYGFLGVIAVIALIVNVVLIIAVLSLLGATLTLPGIAGIVLTIGMAVDSNVLIYERIREEEKTGHSLI 459
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2526274827 422 QAALQGTREVGFTVLSmslSLVAVFLPLLLMGGLPGRLLREFAVTLSVAIGISLIISLTLTPMMCGWMLKRSKPHSQPR 500
Cdd:PRK14726 460 QALDRGFSRALATIVD---ANVTILIAAVILFFLGSGAVRGFAVTLAVGILTTVFTAFTLTRSLVAVWLRRRRPKHLPK 535
|
|
| PRK13024 |
PRK13024 |
bifunctional preprotein translocase subunit SecD/SecF; Reviewed |
329-641 |
7.06e-04 |
|
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
Pssm-ID: 237276 [Multi-domain] Cd Length: 755 Bit Score: 43.68 E-value: 7.06e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 329 ASLEEVEQTLV-------------IS--VALVILVVFLFLRSGRATLIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMALT 393
Cdd:PRK13024 246 APLKIIESRSVgptlgqdaidagiIAgiIGFALIFLFMLVYYGLPGLIANIALLLYIFLTLGALSSLGAVLTLPGIAGLV 325
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 394 IATGFVVDDAIVVLENISRHLEAGVNPLQAALQGTREVGFTVLSMSL-SLVA-----VFLPLLLmgglpgrllREFAVTL 467
Cdd:PRK13024 326 LGIGMAVDANVLIFERIKEELRKGKSLKKAFKKGFKNAFSTILDSNItTLIAaailfFFGTGPV---------KGFATTL 396
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 468 SVAIGISLIISLTLTPMMCGWMLKR--SKPHSQPRRKGFgrvLLAMQEGYGKSLKWVLNHTRLVGLVLIGTIVLnvwlyI 545
Cdd:PRK13024 397 IIGILASLFTAVFLTRLLLELLVKRgdKKPFLFGVKKKK---IHNINEGVTIFDRIDFVKKRKWFLIFSIVLVI-----A 468
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 546 SIPKTFFPEQDTGV-LMGG----IQADQSISFQAMRGKLqdfmkiirEDKAVDNVTGFTGGSRVNSGMmfITLKPRGERN 620
Cdd:PRK13024 469 GIIIFFIFGLNLGIdFTGGtryeIRTDQPVDLEQVRADL--------KELGLGEVNIVTFGSDNNQVL--VRTYGILSDD 538
|
330 340
....*....|....*....|..
gi 2526274827 621 ETAQQ-VIDRLRVKLAKEPGAN 641
Cdd:PRK13024 539 EEADTeIVAKLKNALKNDKGGT 560
|
|
| COG4258 |
COG4258 |
Predicted exporter [General function prediction only]; |
338-404 |
8.56e-04 |
|
Predicted exporter [General function prediction only];
Pssm-ID: 443400 [Multi-domain] Cd Length: 783 Bit Score: 43.30 E-value: 8.56e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2526274827 338 LVISVALVILVVFLFLRSGRATLIpAVAVPV-SLIGTFAAMYLCGFSLNNLSLMALTIATGFVVDDAI 404
Cdd:COG4258 645 LLLALLLILLLLLLRLRSLRRALR-VLLPPLlAVLLTLAILGLLGIPLNLFHLIALLLVLGIGIDYAL 711
|
|
| Patched |
pfam02460 |
Patched family; The transmembrane protein Patched is a receptor for the morphogene Sonic ... |
336-483 |
5.49e-03 |
|
Patched family; The transmembrane protein Patched is a receptor for the morphogene Sonic Hedgehog. This protein associates with the smoothened protein to transduce hedgehog signals.
Pssm-ID: 308203 [Multi-domain] Cd Length: 793 Bit Score: 40.80 E-value: 5.49e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2526274827 336 QTLVISVALVILVVFLFLrsgrATLIPAVAVPVSL----IGTFAAMYLCGFSLNNLSLMALTIATGFVVDDAIVVLENIS 411
Cdd:pfam02460 643 QNIVITLICMFIVCFLFI----PNPPCVFVITLAIasidIGVFGFLSLWGVDLDPISMITIIMSIGFSVDFSAHIAYHFV 718
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2526274827 412 RhlEAGVNPLQAALQGTREVGFTVLSMSLS-LVAVFlpllLMGGLPGRLLREFAVTLSVAIGISLIISLTLTP 483
Cdd:pfam02460 719 R--SRGDTPAERVVDALEALGWPVFQGGLStILGVL----VLLFVPSYMVVVFFKTVFLVVAIGLLHGLFILP 785
|
|
| |
