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Conserved domains on  [gi|2527434832|ref|WP_288450629|]
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glycosyltransferase family 4 protein [uncultured Acinetobacter sp.]

Protein Classification

glycosyltransferase family 4 protein( domain architecture ID 10133538)

glycosyltransferase family 4 (GT4) protein catalyzes the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds

CAZY:  GT4
EC:  2.4.-.-
Gene Ontology:  GO:0016757|GO:0006486
PubMed:  12691742|10521532|16037492
SCOP:  3001586

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
GT4_CapM-like cd03808
capsular polysaccharide biosynthesis glycosyltransferase CapM and similar proteins; This ...
 2-373 6.83e-114

capsular polysaccharide biosynthesis glycosyltransferase CapM and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. CapM in Staphylococcus aureus is required for the synthesis of type 1 capsular polysaccharides.


:

Pssm-ID: 340837 [Multi-domain]  Cd Length: 358  Bit Score: 336.10  E-value: 6.83e-114
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832   2 KFLMISSYLPSVLNFRGKLLEAIATQGHEVVVIAPthaDFPEQVTALTQLGYTVLEVPMQRTGTNPLADLNTLFALYRVI 81
Cdd:cd03808     1 KILFIVNVDGGFQSFRLPLIKALVKKGYEVHVIAP---DGDKLSDELKELGVKVIDIPILRRGINPLKDLKALFKLYKLL 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832  82 RRVQPDMVLSYTIKPVIYGTWAAWLARVPQRFALITGLGYAFqrGEGQAKSLFQRAvhsLYKKALTYSDKVFFQNPDDLA 161
Cdd:cd03808    78 KKEKPDIVHCHTPKPGILGRLAARLAGVPKVIYTVHGLGFVF--TEGKLLRLLYLL---LEKLALLFTDKVIFVNEDDRD 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832 162 LFRHMNLIeRNKPAVVVNGSGIDLAKFdQVELPRQANGQPKVAFllIARLLGDKGVREYAAAAAKIKATYPEIEFHLVGW 241
Cdd:cd03808   153 LAIKKGII-KKKKTVLIPGSGVDLDRF-QYSPESLPSEKVVFLF--VARLLKDKGIDELIEAAKILKKKGPNVRFLLVGD 228

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832 242 IDQNPSAidQKELDQWVQEQRVTYWGKLKDVRPAIAATSVYVLPSYREGTPRTVLEAMAMGRAVITTDAPGCRETVIEGE 321
Cdd:cd03808   229 GELENPS--EILIEKLGLEGRIEFLGFRSDVPELLAESDVFVLPSYREGLPRSLLEAMAAGRPVITTDVPGCRELVIDGV 306

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2527434832 322 NGHLVAVKSVDALVNAMQQCIDQPARVEDMGQRSREIALTKYDVHRVNAHML 373
Cdd:cd03808   307 NGFLVPPGDVEALADAIEKLIEDPELRKEMGEAARKRVEEKFDEEKVVNKLL 358
 
Name Accession Description Interval E-value
GT4_CapM-like cd03808
capsular polysaccharide biosynthesis glycosyltransferase CapM and similar proteins; This ...
 2-373 6.83e-114

capsular polysaccharide biosynthesis glycosyltransferase CapM and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. CapM in Staphylococcus aureus is required for the synthesis of type 1 capsular polysaccharides.


Pssm-ID: 340837 [Multi-domain]  Cd Length: 358  Bit Score: 336.10  E-value: 6.83e-114
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832   2 KFLMISSYLPSVLNFRGKLLEAIATQGHEVVVIAPthaDFPEQVTALTQLGYTVLEVPMQRTGTNPLADLNTLFALYRVI 81
Cdd:cd03808     1 KILFIVNVDGGFQSFRLPLIKALVKKGYEVHVIAP---DGDKLSDELKELGVKVIDIPILRRGINPLKDLKALFKLYKLL 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832  82 RRVQPDMVLSYTIKPVIYGTWAAWLARVPQRFALITGLGYAFqrGEGQAKSLFQRAvhsLYKKALTYSDKVFFQNPDDLA 161
Cdd:cd03808    78 KKEKPDIVHCHTPKPGILGRLAARLAGVPKVIYTVHGLGFVF--TEGKLLRLLYLL---LEKLALLFTDKVIFVNEDDRD 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832 162 LFRHMNLIeRNKPAVVVNGSGIDLAKFdQVELPRQANGQPKVAFllIARLLGDKGVREYAAAAAKIKATYPEIEFHLVGW 241
Cdd:cd03808   153 LAIKKGII-KKKKTVLIPGSGVDLDRF-QYSPESLPSEKVVFLF--VARLLKDKGIDELIEAAKILKKKGPNVRFLLVGD 228

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832 242 IDQNPSAidQKELDQWVQEQRVTYWGKLKDVRPAIAATSVYVLPSYREGTPRTVLEAMAMGRAVITTDAPGCRETVIEGE 321
Cdd:cd03808   229 GELENPS--EILIEKLGLEGRIEFLGFRSDVPELLAESDVFVLPSYREGLPRSLLEAMAAGRPVITTDVPGCRELVIDGV 306

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2527434832 322 NGHLVAVKSVDALVNAMQQCIDQPARVEDMGQRSREIALTKYDVHRVNAHML 373
Cdd:cd03808   307 NGFLVPPGDVEALADAIEKLIEDPELRKEMGEAARKRVEEKFDEEKVVNKLL 358
Glyco_trans_1_4 pfam13692
Glycosyl transferases group 1;
233-343 1.49e-27

Glycosyl transferases group 1;


Pssm-ID: 463957 [Multi-domain]  Cd Length: 138  Bit Score: 105.67  E-value: 1.49e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832 233 EIEFHLVGwidqnpsAIDQKELDQWVQ--EQRVTYWGKLKDVRPAIAATSVYVLPSYREGTPRTVLEAMAMGRAVITTDA 310
Cdd:pfam13692  33 DVRLVIVG-------DGPEEELEELAAglEDRVIFTGFVEDLAELLAAADVFVLPSLYEGFGLKLLEAMAAGLPVVATDV 105

                          90       100       110
                  ....*....|....*....|....*....|...
gi 2527434832 311 PGCREtVIEGENGHLVAVKSVDALVNAMQQCID 343
Cdd:pfam13692 106 GGIPE-LVDGENGLLVPPGDPEALAEAILRLLE 137
RfaB COG0438
Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis]; ...
 275-373 3.38e-27

Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440207 [Multi-domain]  Cd Length: 123  Bit Score: 104.30  E-value: 3.38e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832 275 AIAATSVYVLPSYREGTPRTVLEAMAMGRAVITTDAPGCRETVIEGENGHLVAVKSVDALVNAMQQCIDQPARVEDMGQR 354
Cdd:COG0438    17 LLAAADVFVLPSRSEGFGLVLLEAMAAGLPVIATDVGGLPEVIEDGETGLLVPPGDPEALAEAILRLLEDPELRRRLGEA 96

                          90
                  ....*....|....*....
gi 2527434832 355 SREIALTKYDVHRVNAHML 373
Cdd:COG0438    97 ARERAEERFSWEAIAERLL 115
stp2 TIGR03088
sugar transferase, PEP-CTERM/EpsH1 system associated; Members of this family include a match ...
 45-359 8.98e-17

sugar transferase, PEP-CTERM/EpsH1 system associated; Members of this family include a match to the pfam00534 Glycosyl transferases group 1 domain. Nearly all are found in species that encode the PEP-CTERM/exosortase system predicted to act in protein sorting in a number of Gram-negative bacteria. In particular, these transferases are found proximal to a particular variant of exosortase, EpsH1, which appears to travel with a conserved group of genes summarized by Genome Property GenProp0652. The nature of the sugar transferase reaction catalyzed by members of this clade is unknown and may conceivably be variable with respect to substrate by species, but we hypothesize a conserved substrate.


Pssm-ID: 132132 [Multi-domain]  Cd Length: 374  Bit Score: 80.92  E-value: 8.98e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832  45 VTALTQlgYTVLEVPMQRTGTN-------PLADLNTLFALYRVIRRVQPDMVLSYTIKpVIYGTWAAWLARVPQRFALIT 117
Cdd:TIGR03088  36 VVALTE--VSAFRKRIQRPDVAfyalhkqPGKDVAVYPQLYRLLRQLRPDIVHTRNLA-ALEAQLPAALAGVPARIHGEH 112

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832 118 GLGYAFQRGEGQAKSLFQRAVHSLYKKALTYSDkvffqnpdDLALFrhMNLIERNKPAVVVN-GSGIDLAKF-----DQV 191
Cdd:TIGR03088 113 GRDVFDLDGSNWKYRWLRRLYRPLIHHYVAVSR--------DLEDW--LRGPVKVPPAKIHQiYNGVDTERFhpsrgDRS 182

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832 192 E-LPRQANGQPKVAFLLIARLLGDKG----VREYAAAAAKIKATYPEIEFHLVGWIDQNPSAidQKELDQWVQEQRVTYW 266
Cdd:TIGR03088 183 PiLPPDFFADESVVVGTVGRLQAVKDqptlVRAFALLVRQLPEGAERLRLVIVGDGPARGAC--EQMVRAAGLAHLVWLP 260

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832 267 GKLKDVRPAIAATSVYVLPSYREGTPRTVLEAMAMGRAVITTDAPGCRETVIEGENGHLVAVKSVDALVNAMQQCIDQPA 346
Cdd:TIGR03088 261 GERDDVPALMQALDLFVLPSLAEGISNTILEAMASGLPVIATAVGGNPELVQHGVTGALVPPGDAVALARALQPYVSDPA 340

                         330
                  ....*....|...
gi 2527434832 347 RVEDMGQRSREIA 359
Cdd:TIGR03088 341 ARRAHGAAGRARA 353
PelF NF038011
GT4 family glycosyltransferase PelF; Proteins of this family are components of the ...
 182-320 5.47e-08

GT4 family glycosyltransferase PelF; Proteins of this family are components of the exopolysaccharide Pel transporter. It has been reported that PelF is a soluble glycosyltransferase that uses UDP-glucose as the substrate for the synthesis of exopolysaccharide Pel, whereas PelG is a Wzx-like and PST family exopolysaccharide transporter.


Pssm-ID: 411604 [Multi-domain]  Cd Length: 489  Bit Score: 54.55  E-value: 5.47e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832 182 GIDLAKFDQVELPRQANGQPKVAflLIARLLGDKGVREYAAAAAKIKATYPEIEfhlvGWI----DQNPS-AIDQKELDQ 256
Cdd:NF038011  288 GIDLPRLAPLRAQRPAGIPPVVG--LIGRVVPIKDIKTFIRAMRTVVRAMPEAE----GWIvgpeEEDPAyAAECRSLVA 361

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2527434832 257 WVQ-EQRVTYWG--KLKDVRPAIAatsVYVLPSYREGTPRTVLEAMAMGRAVITTDAPGCREtVIEG 320
Cdd:NF038011  362 SLGlQDKVKFLGfqKIDDLLPQVG---LMVLSSISEALPLVVLEAFAAGVPVVTTDVGSCRQ-LIEG 424
PRK15490 PRK15490
Vi polysaccharide biosynthesis glycosyltransferase TviE;
208-326 2.56e-07

Vi polysaccharide biosynthesis glycosyltransferase TviE;


Pssm-ID: 185387 [Multi-domain]  Cd Length: 578  Bit Score: 52.39  E-value: 2.56e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832 208 IARLLGDKGVREYAAAAAKIKATYPEIEFHLVGwiDQNPSAIDQKELDQWVQEQRVTYWGKLKDVRPAIAATSVYVLPSY 287
Cdd:PRK15490  404 VFRFVGDKNPFAWIDFAARYLQHHPATRFVLVG--DGDLRAEAQKRAEQLGILERILFVGASRDVGYWLQKMNVFILFSR 481

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 2527434832 288 REGTPRTVLEAMAMGRAVITTDAPGCRETVIEGENGHLV 326
Cdd:PRK15490  482 YEGLPNVLIEAQMVGVPVISTPAGGSAECFIEGVSGFIL 520
 
Name Accession Description Interval E-value
GT4_CapM-like cd03808
capsular polysaccharide biosynthesis glycosyltransferase CapM and similar proteins; This ...
 2-373 6.83e-114

capsular polysaccharide biosynthesis glycosyltransferase CapM and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. CapM in Staphylococcus aureus is required for the synthesis of type 1 capsular polysaccharides.


Pssm-ID: 340837 [Multi-domain]  Cd Length: 358  Bit Score: 336.10  E-value: 6.83e-114
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832   2 KFLMISSYLPSVLNFRGKLLEAIATQGHEVVVIAPthaDFPEQVTALTQLGYTVLEVPMQRTGTNPLADLNTLFALYRVI 81
Cdd:cd03808     1 KILFIVNVDGGFQSFRLPLIKALVKKGYEVHVIAP---DGDKLSDELKELGVKVIDIPILRRGINPLKDLKALFKLYKLL 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832  82 RRVQPDMVLSYTIKPVIYGTWAAWLARVPQRFALITGLGYAFqrGEGQAKSLFQRAvhsLYKKALTYSDKVFFQNPDDLA 161
Cdd:cd03808    78 KKEKPDIVHCHTPKPGILGRLAARLAGVPKVIYTVHGLGFVF--TEGKLLRLLYLL---LEKLALLFTDKVIFVNEDDRD 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832 162 LFRHMNLIeRNKPAVVVNGSGIDLAKFdQVELPRQANGQPKVAFllIARLLGDKGVREYAAAAAKIKATYPEIEFHLVGW 241
Cdd:cd03808   153 LAIKKGII-KKKKTVLIPGSGVDLDRF-QYSPESLPSEKVVFLF--VARLLKDKGIDELIEAAKILKKKGPNVRFLLVGD 228

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832 242 IDQNPSAidQKELDQWVQEQRVTYWGKLKDVRPAIAATSVYVLPSYREGTPRTVLEAMAMGRAVITTDAPGCRETVIEGE 321
Cdd:cd03808   229 GELENPS--EILIEKLGLEGRIEFLGFRSDVPELLAESDVFVLPSYREGLPRSLLEAMAAGRPVITTDVPGCRELVIDGV 306

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2527434832 322 NGHLVAVKSVDALVNAMQQCIDQPARVEDMGQRSREIALTKYDVHRVNAHML 373
Cdd:cd03808   307 NGFLVPPGDVEALADAIEKLIEDPELRKEMGEAARKRVEEKFDEEKVVNKLL 358
GT4_PimA-like cd03801
phosphatidyl-myo-inositol mannosyltransferase; This family is most closely related to the GT4 ...
 2-368 6.29e-44

phosphatidyl-myo-inositol mannosyltransferase; This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.


Pssm-ID: 340831 [Multi-domain]  Cd Length: 366  Bit Score: 155.77  E-value: 6.29e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832   2 KFLMISSYLPSVLNFRGK----LLEAIATQGHEVVVIAPTHADFPEqvtaltqlgytvlEVPMQRTGTNPLADLNTLFAL 77
Cdd:cd03801     1 KILLLSPELPPPVGGAERhvreLARALAARGHDVTVLTPADPGEPP-------------EELEDGVIVPLLPSLAALLRA 67

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832  78 YRVIRRVQ-------PDMVLSYTIKPVIYGTWAAWLARVPQRFALITGLGYAFQRGEGQAKSLFQRAVhslykKALTYSD 150
Cdd:cd03801    68 RRLLRELRpllrlrkFDVVHAHGLLAALLAALLALLLGAPLVVTLHGAEPGRLLLLLAAERRLLARAE-----ALLRRAD 142

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832 151 KVFFQNPDDLALFRHMNLIERNKPAVVVNGsgIDLAKFDQVELPRQANGQPKVAFLLIARLLGDKGVREYAAAAAKIKAT 230
Cdd:cd03801   143 AVIAVSEALRDELRALGGIPPEKIVVIPNG--VDLERFSPPLRRKLGIPPDRPVLLFVGRLSPRKGVDLLLEALAKLLRR 220

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832 231 YPEIEFHLVGWIDQNPSAIDQKELDQwvqEQRVTYWGKL--KDVRPAIAATSVYVLPSYREGTPRTVLEAMAMGRAVITT 308
Cdd:cd03801   221 GPDVRLVIVGGDGPLRAELEELELGL---GDRVRFLGFVpdEELPALYAAADVFVLPSRYEGFGLVVLEAMAAGLPVVAT 297

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832 309 DAPGCRETVIEGENGHLVAVKSVDALVNAMQQCIDQPARVEDMGQRSREIALTKYDVHRV 368
Cdd:cd03801   298 DVGGLPEVVEDGEGGLVVPPDDVEALADALLRLLADPELRARLGRAARERVAERFSWERV 357
GT4_WavL-like cd03819
Vibrio cholerae WavL and similar sequences; This family is most closely related to the GT4 ...
 19-359 6.48e-29

Vibrio cholerae WavL and similar sequences; This family is most closely related to the GT4 family of glycosyltransferases. WavL in Vibrio cholerae has been shown to be involved in the biosynthesis of the lipopolysaccharide core.


Pssm-ID: 340846 [Multi-domain]  Cd Length: 345  Bit Score: 115.14  E-value: 6.48e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832  19 KLLEAIATQGHEVVVIAPThadfpeqVTALTQLGYTVLEVPMQRTgtNPLADLNTLFALYRVIRRVQPDMVLSYTIKPVI 98
Cdd:cd03819    19 DLARALAERGHRVLVVTAG-------GPLLPRLRQIGIGLPGLKV--PLLRALLGNVRLARLIRRERIDLIHAHSRAPAW 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832  99 YGTWAAWLARVP--------QRFALITGLGYAFQRgegqAKSLFQRAVHSLYKKALTYSDKVFfqnpddlalfrhmnlie 170
Cdd:cd03819    90 LGWLASRLTGVPlvttvhgsYLATYHPKDFALAVR----ARGDRVIAVSELVRDHLIEALGVD----------------- 148

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832 171 RNKPAVVVNGSGIDLAKFDQVELPRQ----ANGQPKVAFllIARLLGDKGVREYAAAAAKIKATyPEIEFHLVGwiDQNP 246
Cdd:cd03819   149 PERIRVIPNGVDTDRFPPEAEAEERAqlglPEGKPVVGY--VGRLSPEKGWLLLVDAAAELKDE-PDFRLLVAG--DGPE 223

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832 247 SAIDQKELDQWVQEQRVTYWGKLKDVRPAIAATSVYVLPSYREGTPRTVLEAMAMGRAVITTDAPGCRETVIEGENGHLV 326
Cdd:cd03819   224 RDEIRRLVERLGLRDRVTFTGFREDVPAALAASDVVVLPSLHEEFGRVALEAMACGTPVVATDVGGAREIVVHGRTGLLV 303

                         330       340       350
                  ....*....|....*....|....*....|...
gi 2527434832 327 AVKSVDALVNAMQQCIDQPARVEDMGQRSREIA 359
Cdd:cd03819   304 PPGDAEALADAIRAAKLLPEAREKLQAAAALTE 336
Glyco_trans_1_4 pfam13692
Glycosyl transferases group 1;
233-343 1.49e-27

Glycosyl transferases group 1;


Pssm-ID: 463957 [Multi-domain]  Cd Length: 138  Bit Score: 105.67  E-value: 1.49e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832 233 EIEFHLVGwidqnpsAIDQKELDQWVQ--EQRVTYWGKLKDVRPAIAATSVYVLPSYREGTPRTVLEAMAMGRAVITTDA 310
Cdd:pfam13692  33 DVRLVIVG-------DGPEEELEELAAglEDRVIFTGFVEDLAELLAAADVFVLPSLYEGFGLKLLEAMAAGLPVVATDV 105

                          90       100       110
                  ....*....|....*....|....*....|...
gi 2527434832 311 PGCREtVIEGENGHLVAVKSVDALVNAMQQCID 343
Cdd:pfam13692 106 GGIPE-LVDGENGLLVPPGDPEALAEAILRLLE 137
RfaB COG0438
Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis]; ...
 275-373 3.38e-27

Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440207 [Multi-domain]  Cd Length: 123  Bit Score: 104.30  E-value: 3.38e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832 275 AIAATSVYVLPSYREGTPRTVLEAMAMGRAVITTDAPGCRETVIEGENGHLVAVKSVDALVNAMQQCIDQPARVEDMGQR 354
Cdd:COG0438    17 LLAAADVFVLPSRSEGFGLVLLEAMAAGLPVIATDVGGLPEVIEDGETGLLVPPGDPEALAEAILRLLEDPELRRRLGEA 96

                          90
                  ....*....|....*....
gi 2527434832 355 SREIALTKYDVHRVNAHML 373
Cdd:COG0438    97 ARERAEERFSWEAIAERLL 115
GT4_WbnK-like cd03807
Shigella dysenteriae WbnK and similar proteins; This family is most closely related to the GT4 ...
 19-357 6.71e-26

Shigella dysenteriae WbnK and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. WbnK in Shigella dysenteriae has been shown to be involved in the type 7 O-antigen biosynthesis.


Pssm-ID: 340836 [Multi-domain]  Cd Length: 362  Bit Score: 107.02  E-value: 6.71e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832  19 KLLEAIATQGHEVVVIAPTHADfpEQVTALTQLGYTVLEVPMqrtgtNPLADLNTLFALYRVIRRVQPDMVLSYTIKPVI 98
Cdd:cd03807    20 RLLEHMDKSRFEHVVISLTGDG--VLGEELLAAGVPVVCLGL-----SSGKDPGVLLRLAKLIRKRNPDVVHTWMYHADL 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832  99 YGTWAAWLARVPQRFALITglgyafQRGEGQAKSLFQRAVhslyKKALTYSDKVFFQNPDDLALFrHMNLIERNKPAVVV 178
Cdd:cd03807    93 IGGLAAKLAGGVKVIWSVR------SSNIPQRLTRLVRKL----CLLLSKFSPATVANSSAVAEF-HQEQGYAKNKIVVI 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832 179 -NGsgIDLAKFD----QVELPRQANGQPKVAFLLI--ARLLGDKGVREYAAAAAKIKATYPEIEFHLVGWIDQNPSAidQ 251
Cdd:cd03807   162 yNG--IDLFKLSpddaSRARARRRLGLAEDRRVIGivGRLHPVKDHSDLLRAAALLVETHPDLRLLLVGRGPERPNL--E 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832 252 KELDQWVQEQRVTYWGKLKDVRPAIAATSVYVLPSYREGTPRTVLEAMAMGRAVITTDAPGCRETVIEGeNGHLVAVKSV 331
Cdd:cd03807   238 RLLLELGLEDRVHLLGERSDVPALLPAMDIFVLSSRTEGFPNALLEAMACGLPVVATDVGGAAELVDDG-TGFLVPAGDP 316

                         330       340
                  ....*....|....*....|....*.
gi 2527434832 332 DALVNAMQQCIDQPARVEDMGQRSRE 357
Cdd:cd03807   317 QALADAIRALLEDPEKRARLGRAARE 342
GT4_WlbH-like cd03798
Bordetella parapertussis WlbH and similar proteins; This family is most closely related to the ...
 4-359 5.95e-24

Bordetella parapertussis WlbH and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Staphylococcus aureus CapJ may be involved in capsule polysaccharide biosynthesis. WlbH in Bordetella parapertussis has been shown to be required for the biosynthesis of a trisaccharide that, when attached to the B. pertussis lipopolysaccharide (LPS) core (band B), generates band A LPS.


Pssm-ID: 340828 [Multi-domain]  Cd Length: 376  Bit Score: 101.69  E-value: 5.95e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832   4 LMISSYLPSVLNFRG-----KLLEAIATQGHEVVVIAPTHADFPEQVTALTQLGYTVLEVP-MQRTGTNPLADLN----- 72
Cdd:cd03798     2 LILTNIYPNANSPGRgifvrRQVRALSRRGVDVEVLAPAPWGPAAARLLRKLLGEAVPPRDgRRLLPLKPRLRLLaplra 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832  73 -TLFALYRVIRRVQPDMVLsytikpVIYGTWAAWLARvpqRFALITGLGYAF-QRGEGQAKSLFQRAVHSLYKKALTYSD 150
Cdd:cd03798    82 pSLAKLLKRRRRGPPDLIH------AHFAYPAGFAAA---LLARLYGVPYVVtEHGSDINVFPPRSLLRKLLRWALRRAA 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832 151 KVFFQNPDDLALFRhmNLIERNKPAVVVNgSGIDLAKFDQV-ELPRQANGQPKVAFllIARLLGDKGVREYAAAAAKIKA 229
Cdd:cd03798   153 RVIAVSKALAEELV--ALGVPRDRVDVIP-NGVDPARFQPEdRGLGLPLDAFVILF--VGRLIPRKGIDLLLEAFARLAK 227

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832 230 TYPEIEFHLVGwidqnpSAIDQKELDQWVQEQ----RVTYWGKL--KDVRPAIAATSVYVLPSYREGTPRTVLEAMAMGR 303
Cdd:cd03798   228 ARPDVVLLIVG------DGPLREALRALAEDLglgdRVTFTGRLphEQVPAYYRACDVFVLPSRHEGFGLVLLEAMACGL 301

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2527434832 304 AVITTDAPGCRETVIEGENGHLVAVKSVDALVNAMQQCIDQPARVEDMGQRSREIA 359
Cdd:cd03798   302 PVVATDVGGIPEVVGDPETGLLVPPGDADALAAALRRALAEPYLRELGEAARARVA 357
GT4_GT28_WabH-like cd03811
family 4 and family 28 glycosyltransferases similar to Klebsiella WabH; This family is most ...
 20-351 2.26e-23

family 4 and family 28 glycosyltransferases similar to Klebsiella WabH; This family is most closely related to the GT1 family of glycosyltransferases. WabH in Klebsiella pneumoniae has been shown to transfer a GlcNAc residue from UDP-GlcNAc onto the acceptor GalUA residue in the cellular outer core.


Pssm-ID: 340839 [Multi-domain]  Cd Length: 351  Bit Score: 99.74  E-value: 2.26e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832  20 LLEAIATQGHEV-VVIAPTHADFPEQVtaltQLGYTVLEVPMQRTGTNPLADLNTLFALYRVIRRVQPDMVLSYTIKPVI 98
Cdd:cd03811    21 LANALDKRGYDVtLVLLRDEGDLDKQL----NGDVKLIRLLIRVLKLIKLGLLKAILKLKRILKRAKPDVVISFLGFATY 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832  99 YgtWAAWLARVPQRFALITGlgYAFQRGEGQAKSLFQRAvhsLYKKAltysDKVFFQNPDDLALFRHMNLIERNKPAVVV 178
Cdd:cd03811    97 I--VAKLAAARSKVIAWIHS--SLSKLYYLKKKLLLKLK---LYKKA----DKIVCVSKGIKEDLIRLGPSPPEKIEVIY 165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832 179 NGsgIDLAKFDQVELPRQANGQPKVAFLL-IARLLGDKGVREYAAAAAKIKATYPEIEFHLVGWIDQNPSAIDQ-KELDq 256
Cdd:cd03811   166 NP--IDIDRIRALAKEPILNEPEDGPVILaVGRLDPQKGHDLLIEAFAKLRKKYPDVKLVILGDGPLREELEKLaKELG- 242

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832 257 wVQEqRVTYWGKLKDVRPAIAATSVYVLPSYREGTPRTVLEAMAMGRAVITTDAPGCRETVIEGENGHLVAVKSVDALVN 336
Cdd:cd03811   243 -LAE-RVIFLGFQSNPYPYLKKADLFVLSSRYEGFPNVLLEAMALGTPVVSTDCPGPREILDDGENGLLVPDGDAAALAG 320

                         330
                  ....*....|....*
gi 2527434832 337 AMQQCIDQPARVEDM 351
Cdd:cd03811   321 ILAALLQKKLDAALR 335
Glycos_transf_1 pfam00534
Glycosyl transferases group 1; Mutations in this domain of Swiss:P37287 lead to disease ...
 205-357 3.61e-21

Glycosyl transferases group 1; Mutations in this domain of Swiss:P37287 lead to disease (Paroxysmal Nocturnal haemoglobinuria). Members of this family transfer activated sugars to a variety of substrates, including glycogen, Fructose-6-phosphate and lipopolysaccharides. Members of this family transfer UDP, ADP, GDP or CMP linked sugars. The eukaryotic glycogen synthases may be distant members of this family.


Pssm-ID: 425737 [Multi-domain]  Cd Length: 158  Bit Score: 88.87  E-value: 3.61e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832 205 FLLIARLLGDKGVREYAAAAAKIKATYPEIEFHLVGwiDQNpsaiDQKELDQWVQE------QRVTYWGKLKDVRPAIAA 278
Cdd:pfam00534   5 ILFVGRLEPEKGLDLLIKAFALLKEKNPNLKLVIAG--DGE----EEKRLKKLAEKlglgdnVIFLGFVSDEDLPELLKI 78

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2527434832 279 TSVYVLPSYREGTPRTVLEAMAMGRAVITTDAPGCRETVIEGENGHLVAVKSVDALVNAMQQCIDQPARVEDMGQRSRE 357
Cdd:pfam00534  79 ADVFVLPSRYEGFGIVLLEAMACGLPVIASDVGGPPEVVKDGETGFLVKPNNAEALAEAIDKLLEDEELRERLGENARK 157
GT4_WcaC-like cd03825
putative colanic acid biosynthesis glycosyl transferase WcaC and similar proteins; This family ...
 171-364 3.32e-18

putative colanic acid biosynthesis glycosyl transferase WcaC and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Escherichia coli WcaC has been predicted to function in colanic acid biosynthesis. WcfI in Bacteroides fragilis has been shown to be involved in the capsular polysaccharide biosynthesis.


Pssm-ID: 340851 [Multi-domain]  Cd Length: 364  Bit Score: 85.08  E-value: 3.32e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832 171 RNKPAVVVNgSGIDLAKF---DQVELPRQAN-GQPKVAFLLIARLLGD--KGVReYAAAAAKIKATYPEIEFHLVGWIDQ 244
Cdd:cd03825   159 KGLPVVVIP-NGIDTEIFapvDKAKARKRLGiPQDKKVILFGAESVTKprKGFD-ELIEALKLLATKDDLLLVVFGKNDP 236

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832 245 N--PSAIDqkeldqwvqeqrVTYWGKLKDV---RPAIAATSVYVLPSYREGTPRTVLEAMAMGRAVITTDAPGCRETVIE 319
Cdd:cd03825   237 QivILPFD------------IISLGYIDDDeqlVDIYSAADLFVHPSLADNLPNTLLEAMACGTPVVAFDTGGSPEIVQH 304

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 2527434832 320 GENGHLVAVKSVDALVNAMQQCIDQPARVEDMGQRSREIALTKYD 364
Cdd:cd03825   305 GVTGYLVPPGDVQALAEAIEWLLANPKERESLGERARALAENHFD 349
GT4_ExpE7-like cd03823
glycosyltransferase ExpE7 and similar proteins; This family is most closely related to the GT4 ...
 20-363 6.86e-18

glycosyltransferase ExpE7 and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. ExpE7 in Sinorhizobium meliloti has been shown to be involved in the biosynthesis of galactoglucans (exopolysaccharide II).


Pssm-ID: 340850 [Multi-domain]  Cd Length: 357  Bit Score: 83.92  E-value: 6.86e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832  20 LLEAIATQGHEVVVIAPTHAdfPEQVTALTQLGYTVLEVPMQRTGTNPLADLNTLFALY---------RVIRRVQPDMVL 90
Cdd:cd03823    24 LAEALVAEGHEVAVLTAGVG--PPGQATVARSVVRYRRAPDETLPLALKRRGYELFETYnpglrrllaRLLEDFRPDVVH 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832  91 SYTIkpviygtwaawlarvpqrfaliTGLGYAFQRgegQAKSLFQRAVHSLYKKALTY---------SDKVFFQNPDDLA 161
Cdd:cd03823   102 THNL----------------------SGLGASLLD---AARDLGIPVVHTLHDYWLLCprqflfkkgGDAVLAPSRFTAN 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832 162 LFRHmNLIERNKPAVVVNGSGIDLAKfdqveLPRQANGQPKVAFLLIARLLGDKGVreYAAAAAKIKATYPEIEFHLVGw 241
Cdd:cd03823   157 LHEA-NGLFSARISVIPNAVEPDLAP-----PPRRRPGTERLRFGYIGRLTEEKGI--DLLVEAFKRLPREDIELVIAG- 227

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832 242 idqnpSAIDQKELDQWVQEqRVTYWGKLKDVRPAI--AATSVYVLPS-YREGTPRTVLEAMAMGRAVITTDAPGCRETVI 318
Cdd:cd03823   228 -----HGPLSDERQIEGGR-RIAFLGRVPTDDIKDfyEKIDVLVVPSiWPEPFGLVVREAIAAGLPVIASDLGGIAELIQ 301

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*
gi 2527434832 319 EGENGHLVAVKSVDALVNAMQQCIDQPARVEDMGQRSREIALTKY 363
Cdd:cd03823   302 PGVNGLLFAPGDAEDLAAAMRRLLTDPALLERLRAGAEPPRSTES 346
GT4_AmsK-like cd03799
Erwinia amylovora AmsK and similar proteins; This is a family of GT4 glycosyltransferases ...
 176-369 8.09e-18

Erwinia amylovora AmsK and similar proteins; This is a family of GT4 glycosyltransferases found specifically in certain bacteria. AmsK in Erwinia amylovora, has been reported to be involved in the biosynthesis of amylovoran, a exopolysaccharide acting as a virulence factor.


Pssm-ID: 340829 [Multi-domain]  Cd Length: 350  Bit Score: 83.65  E-value: 8.09e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832 176 VVVNGSGIDLAKFdQVELPRQANGQpKVAFLLIARLLGDKGVREYAAAAAKIKATYPEIEFHLVGWID---QNPSAIDQK 252
Cdd:cd03799   150 IIVHRSGIDCNKF-RFKPRYLPLDG-KIRILTVGRLTEKKGLEYAIEAVAKLAQKYPNIEYQIIGDGDlkeQLQQLIQEL 227

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832 253 ELDQWVqeqRVTYWGKLKDVRPAIAATSVYVLPSY------REGTPRTVLEAMAMGRAVITTDAPGCRETVIEGENGHLV 326
Cdd:cd03799   228 NIGDCV---KLLGWKPQEEIIEILDEADIFIAPSVtaadgdQDGPPNTLKEAMAMGLPVISTEHGGIPELVEDGVSGFLV 304

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 2527434832 327 AVKSVDALVNAMQQCIDQPARVEDMGQRSREIALTKYDVHRVN 369
Cdd:cd03799   305 PERDAEAIAEKLTYLIEHPAIWPEMGKAGRARVEEEYDINKLN 347
GT4_Bme6-like cd03821
Brucella melitensis Bme6 and similar proteins; This family is most closely related to the GT4 ...
 127-360 9.01e-18

Brucella melitensis Bme6 and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Bme6 in Brucella melitensis has been shown to be involved in the biosynthesis of a polysaccharide.


Pssm-ID: 340848 [Multi-domain]  Cd Length: 377  Bit Score: 83.96  E-value: 9.01e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832 127 EGQAKSLFQRAVHSLYKKALTYSDKVFFQNPDDLALFRHMNLieRNKPAVVVNGsgIDLAKFD-QVELPRQANGQPKVAF 205
Cdd:cd03821   131 LQQKHWKKRIALHLIERRNLNNAALVHFTSEQEADELRRFGL--EPPIAVIPNG--VDIPEFDpGLRDRRKHNGLEDRRI 206

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832 206 LL-IARLLGDKGVREYAAAAAKIKATYPEIEFHLVGWIDQNPSAIDQKELDQWVQEqRVTYWGKLK-DVRPAI-AATSVY 282
Cdd:cd03821   207 ILfLGRIHPKKGLDLLIRAARKLAEQGRDWHLVIAGPDDGAYPAFLQLQSSLGLGD-RVTFTGPLYgEAKWALyASADLF 285

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2527434832 283 VLPSYREGTPRTVLEAMAMGRAVITTDAPGCREtVIEGENGhLVAVKSVDALVNAMQQCIDQPARVEDMGQRSREIAL 360
Cdd:cd03821   286 VLPSYSENFGNVVAEALACGLPVVITDKCGLSE-LVEAGCG-VVVDPNVSSLAEALAEALRDPADRKRLGEMARRARQ 361
GT4_WbuB-like cd03794
Escherichia coli WbuB and similar proteins; This family is most closely related to the GT1 ...
 2-365 7.23e-17

Escherichia coli WbuB and similar proteins; This family is most closely related to the GT1 family of glycosyltransferases. WbuB in E. coli is involved in the biosynthesis of the O26 O-antigen. It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase.


Pssm-ID: 340825 [Multi-domain]  Cd Length: 391  Bit Score: 81.23  E-value: 7.23e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832   2 KFLMIS-SYLPSVLNFRG---KLLEAIATQGHEVVVIAPTHADFPEQVTALTQ---LGYTVLEVPM-QRTGTNPLADLNT 73
Cdd:cd03794     1 KILLISqYYPPPKGAAAArvyELAKELVRRGHEVTVLTPSPNYPLGRIFAGATetkDGIRVIRVKLgPIKKNGLIRRLLN 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832  74 LF------ALYRVIRRVQPDMVLSYTIKPVIY--GTWAAWLARVPqrFALI-----------TGLGYafqrgegqaKSLF 134
Cdd:cd03794    81 YLsfalaaLLKLLVREERPDVIIAYSPPITLGlaALLLKKLRGAP--FILDvrdlwpesliaLGVLK---------KGSL 149

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832 135 QRAVHSLYKKALTYSDKVFFQNPDDLALFRHMNlIERNKPAVVVNGSGIDLAKFDQVELPRQANGQPKVAFLLIARLLGD 214
Cdd:cd03794   150 LKLLKKLERKLYRLADAIIVLSPGLKEYLLRKG-VPKEKIIVIPNWADLEEFKPPPKDELRKKLGLDDKFVVVYAGNIGK 228

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832 215 KGVREYAAAAAKIKATYPEIEFHLVGWIDQNPSAIDQKELDQWvqeQRVTYWGKL--KDVRPAIAATSVYVLP-----SY 287
Cdd:cd03794   229 AQGLETLLEAAERLKRRPDIRFLFVGDGDEKERLKELAKARGL---DNVTFLGRVpkEEVPELLSAADVGLVPlkdnpAN 305

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2527434832 288 REGTPRTVLEAMAMGRAVITTDAPGCRETVIEGENGHLVAVKSVDALVNAMQQCIDQPARVEDMGQRSREIALTKYDV 365
Cdd:cd03794   306 RGSSPSKLFEYMAAGKPILASDDGGSDLAVEINGCGLVVEPGDPEALADAILELLDDPELRRAMGENGRELAEEKFSR 383
GT4_AmsD-like cd03820
amylovoran biosynthesis glycosyltransferase AmsD and similar proteins; This family is most ...
 22-359 8.63e-17

amylovoran biosynthesis glycosyltransferase AmsD and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. AmSD in Erwinia amylovora has been shown to be involved in the biosynthesis of amylovoran, the acidic exopolysaccharide acting as a virulence factor. This enzyme may be responsible for the formation of galactose alpha-1,6 linkages in amylovoran.


Pssm-ID: 340847 [Multi-domain]  Cd Length: 351  Bit Score: 80.74  E-value: 8.63e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832  22 EAIATQGHEVVVI------APTHADFPEQVTaLTQLGytvleVPMQRTGTNPLADLNTLFALYRVIRRVQPDMVLSYTik 95
Cdd:cd03820    24 NHLAKKGYDVTIIsldsaeKPPFYELDDNIK-IKNLG-----DRKYSHFKLLLKYFKKVRRLRKYLKNNKPDVVISFR-- 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832  96 PVIYGTWAAWLARVP----QRFAlitglgYAFQRGEGQAKSLFQRavhsLYKKA-----LTYSDKVFFQNPDdlalfrhm 166
Cdd:cd03820    96 TSLLTFLALIGLKSKlivwEHNN------YEAYNKGLRRLLLRRL----LYKRAdkivvLTEADKLKKYKQP-------- 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832 167 nlierNKPAVVVNGSgIDLAKFDQVELPRQangqpKVaFLLIARLLGDKGVREYAAAAAKIKATYPEIEFHLVGwidqnp 246
Cdd:cd03820   158 -----NSNVVVIPNP-LSFPSEEPSTNLKS-----KR-ILAVGRLTYQKGFDLLIEAWALIAKKHPDWKLRIYG------ 219

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832 247 SAIDQKELDQWVQ----EQRVTYWGKLKDVRPAIAATSVYVLPSYREGTPRTVLEAMAMGRAVITTDAP-GCRETVIEGE 321
Cdd:cd03820   220 DGPEREELEKLIDklglEDRVKLLGPTKNIAEEYANSSIFVLSSRYEGFPMVLLEAMAYGLPIISFDCPtGPSEIIEDGE 299

                         330       340       350
                  ....*....|....*....|....*....|....*...
gi 2527434832 322 NGHLVAVKSVDALVNAMQQCIDQPARVEDMGQRSREIA 359
Cdd:cd03820   300 NGLLVPNGDVDALAEALLRLMEDEELRKKMGKNARKNA 337
stp2 TIGR03088
sugar transferase, PEP-CTERM/EpsH1 system associated; Members of this family include a match ...
 45-359 8.98e-17

sugar transferase, PEP-CTERM/EpsH1 system associated; Members of this family include a match to the pfam00534 Glycosyl transferases group 1 domain. Nearly all are found in species that encode the PEP-CTERM/exosortase system predicted to act in protein sorting in a number of Gram-negative bacteria. In particular, these transferases are found proximal to a particular variant of exosortase, EpsH1, which appears to travel with a conserved group of genes summarized by Genome Property GenProp0652. The nature of the sugar transferase reaction catalyzed by members of this clade is unknown and may conceivably be variable with respect to substrate by species, but we hypothesize a conserved substrate.


Pssm-ID: 132132 [Multi-domain]  Cd Length: 374  Bit Score: 80.92  E-value: 8.98e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832  45 VTALTQlgYTVLEVPMQRTGTN-------PLADLNTLFALYRVIRRVQPDMVLSYTIKpVIYGTWAAWLARVPQRFALIT 117
Cdd:TIGR03088  36 VVALTE--VSAFRKRIQRPDVAfyalhkqPGKDVAVYPQLYRLLRQLRPDIVHTRNLA-ALEAQLPAALAGVPARIHGEH 112

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832 118 GLGYAFQRGEGQAKSLFQRAVHSLYKKALTYSDkvffqnpdDLALFrhMNLIERNKPAVVVN-GSGIDLAKF-----DQV 191
Cdd:TIGR03088 113 GRDVFDLDGSNWKYRWLRRLYRPLIHHYVAVSR--------DLEDW--LRGPVKVPPAKIHQiYNGVDTERFhpsrgDRS 182

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832 192 E-LPRQANGQPKVAFLLIARLLGDKG----VREYAAAAAKIKATYPEIEFHLVGWIDQNPSAidQKELDQWVQEQRVTYW 266
Cdd:TIGR03088 183 PiLPPDFFADESVVVGTVGRLQAVKDqptlVRAFALLVRQLPEGAERLRLVIVGDGPARGAC--EQMVRAAGLAHLVWLP 260

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832 267 GKLKDVRPAIAATSVYVLPSYREGTPRTVLEAMAMGRAVITTDAPGCRETVIEGENGHLVAVKSVDALVNAMQQCIDQPA 346
Cdd:TIGR03088 261 GERDDVPALMQALDLFVLPSLAEGISNTILEAMASGLPVIATAVGGNPELVQHGVTGALVPPGDAVALARALQPYVSDPA 340

                         330
                  ....*....|...
gi 2527434832 347 RVEDMGQRSREIA 359
Cdd:TIGR03088 341 ARRAHGAAGRARA 353
Glycosyltransferase_GTB-type cd01635
glycosyltransferase family 1 and related proteins with GTB topology; Glycosyltransferases ...
 150-326 9.07e-17

glycosyltransferase family 1 and related proteins with GTB topology; Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. The structures of the formed glycoconjugates are extremely diverse, reflecting a wide range of biological functions. The members of this family share a common GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.


Pssm-ID: 340816 [Multi-domain]  Cd Length: 235  Bit Score: 78.99  E-value: 9.07e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832 150 DKVFFQNPDDLALFRHMNLIERNKPAVVVNGSGIDLAKFDQVEL--PRQANGQPKVAFLLIARLLGDKGVREYAAAAAKI 227
Cdd:cd01635    56 DVVHAHSPHAAALAALLAARLLGIPIVVTVHGPDSLESTRSELLalARLLVSLPLADKVSVGRLVPEKGIDLLLEALALL 135

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832 228 KATYPEIEFHLVGWIDQNPSAIDQKELDQWVQEQRVTYWGKLKDVRPAIAATS-VYVLPSYREGTPRTVLEAMAMGRAVI 306
Cdd:cd01635   136 KARLPDLVLVLVGGGGEREEEEALAAALGLLERVVIIGGLVDDEVLELLLAAAdVFVLPSRSEGFGLVLLEAMAAGKPVI 215

                         170       180
                  ....*....|....*....|
gi 2527434832 307 TTDAPGCRETVIEGENGHLV 326
Cdd:cd01635   216 ATDVGGIPEFVVDGENGLLV 235
GT4-like cd03813
glycosyltransferase family 4 proteins; This family is most closely related to the GT4 family ...
 131-368 4.57e-16

glycosyltransferase family 4 proteins; This family is most closely related to the GT4 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria, while some of them are also found in Archaea and eukaryotes.


Pssm-ID: 340841 [Multi-domain]  Cd Length: 474  Bit Score: 79.30  E-value: 4.57e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832 131 KSLFQRAVHSLYKKALTYSDKVffqnpddLALFRHMNLIE------RNKPAVVVNGsgIDLAKFDQVELPRQANGQPKVA 204
Cdd:cd03813   227 KKLWIRFFERLGKLAYQQADKI-------ISLYEGNRRRQirlgadPDKTRVIPNG--IDIQRFAPAREERPEKEPPVVG 297

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832 205 flLIARLLGDKGVREYAAAAAKIKATYPEIEFHLVGWIDQNPSAIDQ-KEL-DQWVQEQRVTYWGkLKDVRPAIAATSVY 282
Cdd:cd03813   298 --LVGRVVPIKDVKTFIRAFKLVRRAMPDAEGWLIGPEDEDPEYAQEcKRLvASLGLENKVKFLG-FQNIKEYYPKLGLL 374

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832 283 VLPSYREGTPRTVLEAMAMGRAVITTDAPGCREtVIE------GENGHLVAVKSVDALVNAMQQCIDQPARVEDMGQRSR 356
Cdd:cd03813   375 VLTSISEGQPLVILEAMASGVPVVATDVGSCRE-LIYgaddalGQAGLVVPPADPEALAEALIKLLRDPELRQAFGEAGR 453

                         250
                  ....*....|..
gi 2527434832 357 EIALTKYDVHRV 368
Cdd:cd03813   454 KRVEKYYTLEGM 465
GT4_GtfA-like cd04949
accessory Sec system glycosyltransferase GtfA and similar proteins; This family is most ...
 188-359 1.55e-13

accessory Sec system glycosyltransferase GtfA and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases and is named after gtfA in Streptococcus gordonii, where it plays a role in the O-linked glycosylation of GspB, a cell surface glycoprotein involved in platelet binding. In general glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found in bacteria.


Pssm-ID: 340855 [Multi-domain]  Cd Length: 328  Bit Score: 70.79  E-value: 1.55e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832 188 FDQVELPRQANGQPKVAFLLIARLLGDKGVREYAAAAAKIKATYPEIEFHLVGWID--QNPSA-IDQKELdqwvqEQRVT 264
Cdd:cd04949   146 VDQLDTAESNHERKSNKIITISRLAPEKQLDHLIEAVAKAVKKVPEITLDIYGYGEerEKLKKlIEELHL-----EDNVF 220

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832 265 YWGKLKDVRPAIAATSVYVLPSYREGTPRTVLEAMAMGRAVITTDAP-GCRETVIEGENGHLVAVKSVDALVNAMQQCID 343
Cdd:cd04949   221 LKGYHSNLDQEYQDAYLSLLTSQMEGFGLTLMEAIGHGLPVVSYDVKyGPSELIEDGENGYLIEKNNIDALADKIIELLN 300

                         170
                  ....*....|....*.
gi 2527434832 344 QPARVEDMGQRSREIA 359
Cdd:cd04949   301 DPEKLQQFSEESYKIA 316
GT4_BshA-like cd04962
N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA and similar proteins; This family is most ...
 260-368 1.35e-12

N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA and similar proteins; This family is most closely related to the GT1 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria, while some of them are also found in Archaea and eukaryotes.


Pssm-ID: 340859 [Multi-domain]  Cd Length: 370  Bit Score: 68.15  E-value: 1.35e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832 260 EQRVTYWGKLKDVRPAIAATSVYVLPSYREGTPRTVLEAMAMGRAVITTDAPGCRETVIEGENGHLVAVKSVDALVNAMQ 339
Cdd:cd04962   251 EDRVLFLGKQDDVEELLSIADLFLLPSEKESFGLAALEAMACGVPVVSSNAGGIPEVVKHGETGFLSDVGDVDAMAKSAL 330

                          90       100
                  ....*....|....*....|....*....
gi 2527434832 340 QCIDQPARVEDMGQRSREIALTKYDVHRV 368
Cdd:cd04962   331 SILEDDELYNRMGRAARKRAAERFDPERI 359
Glyco_trans_4_4 pfam13579
Glycosyl transferase 4-like domain;
20-180 1.58e-12

Glycosyl transferase 4-like domain;


Pssm-ID: 433325 [Multi-domain]  Cd Length: 158  Bit Score: 64.73  E-value: 1.58e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832  20 LLEAIATQGHEVVVIAPTHadfPEQVTALTQLGYTVLEVPMQRTGTnPLADLNTLFALYRVIRRVQPDMVLSYTIKPVIY 99
Cdd:pfam13579  10 LARALAALGHEVRVVTPGG---PPGRPELVGDGVRVHRLPVPPRPS-PLADLAALRRLRRLLRAERPDVVHAHSPTAGLA 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832 100 GTWAAWLARVPqrfALITGLGYAFQRGEGQAKSLFQRAVHSLYKKAltysDKVFFQNPDDLALFRHMNlIERNKPAVVVN 179
Cdd:pfam13579  86 ARLARRRRGVP---LVVTVHGLALDYGSGWKRRLARALERRLLRRA----DAVVVVSEAEAELLRALG-VPAARVVVVPN 157


                  .
gi 2527434832 180 G 180
Cdd:pfam13579 158 G 158
GT4_UGDG-like cd03817
UDP-Glc:1,2-diacylglycerol 3-a-glucosyltransferase and similar proteins; This family is most ...
 8-360 2.32e-11

UDP-Glc:1,2-diacylglycerol 3-a-glucosyltransferase and similar proteins; This family is most closely related to the GT1 family of glycosyltransferases. UDP-glucose-diacylglycerol glucosyltransferase (EC 2.4.1.337, UGDG; also known as 1,2-diacylglycerol 3-glucosyltransferase) catalyzes the transfer of glucose from UDP-glucose to 1,2-diacylglycerol forming 3-D-glucosyl-1,2-diacylglycerol.


Pssm-ID: 340844 [Multi-domain]  Cd Length: 372  Bit Score: 64.61  E-value: 2.32e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832   8 SYLP-------SVLNFRgkllEAIATQGHEVVVIAPTH--ADFPEQVtaltqLGYTVLEVPMQRTGTNPLAdLNTLFALY 78
Cdd:cd03817     8 TYLPqvngvatSVRNLA----RALEKRGHEVYVITPSDpgAEDEEEV-----VRYRSFSIPIRKYHRQHIP-FPFKKAVI 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832  79 RVIRRVQPDMVLSYTikPVIYGTWAAWLAR---VPQRFALITG----LGYAfqrgeGQAKSLFQRAVHSLYKKALTYSDK 151
Cdd:cd03817    78 DRIKELGPDIIHTHT--PFSLGKLGLRIARklkIPIVHTYHTMyedyLHYI-----PKGKLLVKAVVRKLVRRFYNHTDA 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832 152 VFFQNPDDLALfrhmnLIERN--KPAVVVNgSGIDLAKF---DQVELPRQAN---GQPKVAFLliARLLGDKGVrEYAAA 223
Cdd:cd03817   151 VIAPSEKIKDT-----LREYGvkGPIEVIP-NGIDLDKFekpLNTEERRKLGlppDEPILLYV--GRLAKEKNI-DFLLR 221

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832 224 AAKIKATYPEIEFHLVGwidQNPsaiDQKELDQWVQE----QRVTYWGKLKDVR-PAIAATS-VYVLPSYREGTPRTVLE 297
Cdd:cd03817   222 AFAELKKEPNIKLVIVG---DGP---EREELKELARElglaDKVIFTGFVPREElPEYYKAAdLFVFASTTETQGLVYLE 295

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2527434832 298 AMAMGRAVITTDAPGCRETVIEGENGHLVAVKSVdALVNAMQQCIDQPARVEDMGQRSREIAL 360
Cdd:cd03817   296 AMAAGLPVVAAKDPAASELVEDGENGFLFEPNDE-TLAEKLLHLRENLELLRKLSKNAEISAR 357
GT4-like cd05844
glycosyltransferase family 4 proteins; Glycosyltransferases catalyze the transfer of sugar ...
 168-373 4.43e-11

glycosyltransferase family 4 proteins; Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to glycosyltransferase family 4 (GT4). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.


Pssm-ID: 340860 [Multi-domain]  Cd Length: 365  Bit Score: 63.63  E-value: 4.43e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832 168 LIERNKPA--VVVNGSGIDLAKFdqveLPRQAnGQPKVAFLLIARLLGDKGVREYAAAAAKIKATYPEIEFHLVGwidqn 245
Cdd:cd05844   158 LLARGLPAerIHVHYIGIDPAKF----APRDP-AERAPTILFVGRLVEKKGCDVLIEAFRRLAARHPTARLVIAG----- 227

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832 246 PSAIDQKELDQWVQEQRVTYWGKL--KDVRPAIAATSVYVLPSY------REGTPRTVLEAMAMGRAVITTDAPGCRETV 317
Cdd:cd05844   228 DGPLRPALQALAAALGRVRFLGALphAEVQDWMRRAEIFCLPSVtaasgdSEGLGIVLLEAAACGVPVVSSRHGGIPEAI 307

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2527434832 318 IEGENGHLVAVKSVDALVNAMQQCIDQPARVEDMGQRSREIALTKYDVhRVNAHML 373
Cdd:cd05844   308 LDGETGFLVPEGDVDALADALQALLADRALADRMGGAARAFVCEQFDI-RVQTAKL 362
GT4_WbdM_like cd04951
LPS/UnPP-GlcNAc-Gal a-1,4-glucosyltransferase WbdM and similar proteins; This family is most ...
 171-365 4.60e-11

LPS/UnPP-GlcNAc-Gal a-1,4-glucosyltransferase WbdM and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases and is named after WbdM in Escherichia coli. In general glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found in bacteria.


Pssm-ID: 340857 [Multi-domain]  Cd Length: 360  Bit Score: 63.62  E-value: 4.60e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832 171 RNKPAVVVNGsgIDLAKFDQVELPRQA-------NGQPKVaFLLIARLLGDKGVREYAAAAAKIKATYPEIEFHLVGwid 243
Cdd:cd04951   153 KNKSVPVYNG--IDLNKFKKDINVRLKirnklnlKNDEFV-ILNVGRLTEAKDYPNLLLAISELILSKNDFKLLIAG--- 226

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832 244 QNPSAIDQKEL-DQWVQEQRVTYWGKLKDVRPAIAATSVYVLPSYREGTPRTVLEAMAMGRAVITTDAPGCRETVieGEN 322
Cdd:cd04951   227 DGPLRNELERLiCNLNLVDRVILLGQISNISEYYNAADLFVLSSEWEGFGLVVAEAMACERPVVATDAGGVAEVV--GDH 304

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 2527434832 323 GHLVAVKSVDALVNAMQQCIDQPARVEDMGQRSREIALTKYDV 365
Cdd:cd04951   305 NYVVPVSDPQLLAEKIKEIFDMSDEERDILGNKNEYIAKNFSI 347
GT4-like cd03814
glycosyltransferase family 4 proteins; This family is most closely related to the GT4 family ...
 3-377 7.43e-11

glycosyltransferase family 4 proteins; This family is most closely related to the GT4 family of glycosyltransferases and includes a sequence annotated as alpha-D-mannose-alpha(1-6)phosphatidyl myo-inositol monomannoside transferase from Bacillus halodurans. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria and eukaryotes.


Pssm-ID: 340842 [Multi-domain]  Cd Length: 365  Bit Score: 63.08  E-value: 7.43e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832   3 FLMISSYLPS---VLNFRGKLLEAIATQGHEVVVIAPTHADFPEQVTALTqlgYTVLEVPMQRTGTNPLADLNTLfALYR 79
Cdd:cd03814     3 ALVTDTYHPQvngVVRTLERLVDHLRRRGHEVRVVAPGPFDEAESAEGRV---VSVPSFPLPFYPEYRLALPLPR-RVRR 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832  80 VIRRVQPDMVLSYTikPVIYGTWAAWLAR---VP------QRFAlitglGYAFQRGEGQAKSLFQRAVHSLYKKAltysD 150
Cdd:cd03814    79 LIKEFQPDIIHIAT--PGPLGLAALRAARrlgLPvvtsyhTDFP-----EYLSYYTLGPLSWLAWAYLRWFHNPF----D 147

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832 151 KVFFQNPDDLALFRHmNLIERnkpaVVVNGSGIDLAKFD---QVELPRQANGQP-KVAFLLIARLLGDKGVREYAAAAAK 226
Cdd:cd03814   148 TTLVPSPSIARELEG-HGFER----VRLWPRGVDTELFHpsrRDAALRRRLGPPgRPLLLYVGRLAPEKNLEALLDADLP 222

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832 227 IKATYPeieFHLVgWIDQNPSAidqkeldQWVQEQR--VTYWGKLK--DVRPAIAATSVYVLPSYREGTPRTVLEAMAMG 302
Cdd:cd03814   223 LAASPP---VRLV-VVGDGPAR-------AELEARGpdVIFTGFLTgeELARAYASADVFVFPSRTETFGLVVLEAMASG 291

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2527434832 303 RAVITTDAPGCRETVIEGENGHLVAVKSVDALVNAMQQCIDQPARVEDMGQRSREIALTkYDVHRVNAHMLTEMG 377
Cdd:cd03814   292 LPVVAADAGGPRDIVRPGGTGALVEPGDAAAFAAALRALLEDPELRRRMAARARAEAER-YSWEAFLDNLLDYYA 365
Glyco_trans_4_2 pfam13477
Glycosyl transferase 4-like;
19-156 8.52e-11

Glycosyl transferase 4-like;


Pssm-ID: 433241 [Multi-domain]  Cd Length: 139  Bit Score: 59.26  E-value: 8.52e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832  19 KLLEAIATQGHEVVVIAPTHADFPEQVTAltqlGYTVLEVPMQRTGtnPLADLNtLFALYRVIRRVQPDMVLSYTIKPV- 97
Cdd:pfam13477  15 RWADALADRGYDVHVISSKGPAKDELIAE----GIHVHRLKVPRKG--PLGYLK-AFRLKKLIKKIKPDVVHVHYAKPYg 87

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832  98 IYGTWAAWLARVPQRFALITGLG-YAFQRgegqaKSLFQRAvhsLYKKALTYSDKVFFQN 156
Cdd:pfam13477  88 LLAGLAARLSGFPPVVLSAWGLDvYKFPN-----KSRLKKL---LLKLNLKKATLIISTS 139
GT4_sucrose_synthase cd03800
sucrose-phosphate synthase and similar proteins; This family is most closely related to the ...
 232-374 3.09e-10

sucrose-phosphate synthase and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. The sucrose-phosphate synthases in this family may be unique to plants and photosynthetic bacteria. This enzyme catalyzes the synthesis of sucrose 6-phosphate from fructose 6-phosphate and uridine 5'-diphosphate-glucose, a key regulatory step of sucrose metabolism. The activity of this enzyme is regulated by phosphorylation and moderated by the concentration of various metabolites and light.


Pssm-ID: 340830 [Multi-domain]  Cd Length: 398  Bit Score: 61.10  E-value: 3.09e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832 232 PEIEFHLVGWIDQNPSAIDQKELDQWVQE----QRVTYWGKLKDVR-PAI-AATSVYVLPSYREGTPRTVLEAMAMGRAV 305
Cdd:cd03800   250 ELANLVLVGGPSDDPLSMDREELAELAEElgliDRVRFPGRVSRDDlPELyRAADVFVVPSLYEPFGLTAIEAMACGTPV 329

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2527434832 306 ITTDAPGCRETVIEGENGHLVAVKSVDALVNAMQQCIDQPARVEDMGQRSREIALTKYDVHRVNAHMLT 374
Cdd:cd03800   330 VATAVGGLQDIVRDGRTGLLVDPHDPEALAAALRRLLDDPALWQRLSRAGLERARAHYTWESVADQLLT 398
GT4_ExpC-like cd03818
Rhizobium meliloti ExpC and similar proteins; This family is most closely related to the GT4 ...
 295-370 1.21e-09

Rhizobium meliloti ExpC and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. ExpC in Rhizobium meliloti has been shown to be involved in the biosynthesis of galactoglucan (exopolysaccharide II).


Pssm-ID: 340845 [Multi-domain]  Cd Length: 396  Bit Score: 59.30  E-value: 1.21e-09
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2527434832 295 VLEAMAMGRAVITTDAPGCRETVIEGENGHLVAVKSVDALVNAMQQCIDQPARVEDMGQRSREIALTKYDVHRVNA 370
Cdd:cd03818   317 LLEAMACGCPVIGSDTAPVREVIRDGRNGLLVDFFDPDALAAAVLELLEDPDRAAALRRAARRTVERSDSLDVCLA 392
GT4_MtfB-like cd03809
glycosyltransferases MtfB, WbpX, and similar proteins; This family is most closely related to ...
 231-359 1.99e-09

glycosyltransferases MtfB, WbpX, and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. MtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the previously synthesized polysaccharide.


Pssm-ID: 340838 [Multi-domain]  Cd Length: 362  Bit Score: 58.53  E-value: 1.99e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832 231 YPEIEFHLVGwIDQNPSAIDQKELDQWVQEQRVTYWGKL--KDVRPAIAATSVYVLPSYREGTPRTVLEAMAMGRAVITT 308
Cdd:cd03809   221 GGDLKLVIVG-GKGWEDEELLDLVKKLGLGGRVRFLGYVsdEDLPALYRGARAFVFPSLYEGFGLPVLEAMACGTPVIAS 299

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2527434832 309 DAPGCREtvIEGENGHLVAVKSVDALVNAMQQCIDQPARVEDMGQRSREIA 359
Cdd:cd03809   300 NISVLPE--VAGDAALYFDPLDPESIADAILRLLEDPSLREELIRKGLERA 348
Glyco_transf_4 pfam13439
Glycosyltransferase Family 4;
20-186 4.25e-09

Glycosyltransferase Family 4;


Pssm-ID: 463877 [Multi-domain]  Cd Length: 169  Bit Score: 55.23  E-value: 4.25e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832  20 LLEAIATQGHEVVVIAPTHADFPEQVtaltQLGYTVLEVPMQRTGTNPLADLNTLFALYRVIRRVQPDMVLSYTIKPVIY 99
Cdd:pfam13439  10 LARALARRGHEVTVVTPGGPGPLAEE----VVRVVRVPRVPLPLPPRLLRSLAFLRRLRRLLRRERPDVVHAHSPFPLGL 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832 100 GTWAAWLARvpqRFALITGL--GYAFQRGEGQAKSLFQRAVHSLYKKALTYSDKVFFQNPDDLALFRHMNLIERNKPAVV 177
Cdd:pfam13439  86 AALAARLRL---GIPLVVTYhgLFPDYKRLGARLSPLRRLLRRLERRLLRRADRVIAVSEAVADELRRLYGVPPEKIRVI 162


                  ....*....
gi 2527434832 178 VNgsGIDLA 186
Cdd:pfam13439 163 PN--GVDLE 169
PelF NF038011
GT4 family glycosyltransferase PelF; Proteins of this family are components of the ...
 182-320 5.47e-08

GT4 family glycosyltransferase PelF; Proteins of this family are components of the exopolysaccharide Pel transporter. It has been reported that PelF is a soluble glycosyltransferase that uses UDP-glucose as the substrate for the synthesis of exopolysaccharide Pel, whereas PelG is a Wzx-like and PST family exopolysaccharide transporter.


Pssm-ID: 411604 [Multi-domain]  Cd Length: 489  Bit Score: 54.55  E-value: 5.47e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832 182 GIDLAKFDQVELPRQANGQPKVAflLIARLLGDKGVREYAAAAAKIKATYPEIEfhlvGWI----DQNPS-AIDQKELDQ 256
Cdd:NF038011  288 GIDLPRLAPLRAQRPAGIPPVVG--LIGRVVPIKDIKTFIRAMRTVVRAMPEAE----GWIvgpeEEDPAyAAECRSLVA 361

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2527434832 257 WVQ-EQRVTYWG--KLKDVRPAIAatsVYVLPSYREGTPRTVLEAMAMGRAVITTDAPGCREtVIEG 320
Cdd:NF038011  362 SLGlQDKVKFLGfqKIDDLLPQVG---LMVLSSISEALPLVVLEAFAAGVPVVTTDVGSCRQ-LIEG 424
PRK15490 PRK15490
Vi polysaccharide biosynthesis glycosyltransferase TviE;
208-326 2.56e-07

Vi polysaccharide biosynthesis glycosyltransferase TviE;


Pssm-ID: 185387 [Multi-domain]  Cd Length: 578  Bit Score: 52.39  E-value: 2.56e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832 208 IARLLGDKGVREYAAAAAKIKATYPEIEFHLVGwiDQNPSAIDQKELDQWVQEQRVTYWGKLKDVRPAIAATSVYVLPSY 287
Cdd:PRK15490  404 VFRFVGDKNPFAWIDFAARYLQHHPATRFVLVG--DGDLRAEAQKRAEQLGILERILFVGASRDVGYWLQKMNVFILFSR 481

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 2527434832 288 REGTPRTVLEAMAMGRAVITTDAPGCRETVIEGENGHLV 326
Cdd:PRK15490  482 YEGLPNVLIEAQMVGVPVISTPAGGSAECFIEGVSGFIL 520
Glyco_trans_1_2 pfam13524
Glycosyl transferases group 1;
281-368 6.41e-07

Glycosyl transferases group 1;


Pssm-ID: 433281 [Multi-domain]  Cd Length: 93  Bit Score: 47.21  E-value: 6.41e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832 281 VYVLPSYREGTP-RTVLEAMAMGRAVITTDAPGCRETVIEGEngHLVAVKSVDALVNAMQQCIDQPARVEDMGQRSREIA 359
Cdd:pfam13524   1 IVLNPSRRPDSPnMRVFEAAACGAPLLTDRTPGLEELFEPGE--EILLYRDPEELAEKIRYLLEHPEERRAIAAAGRERV 78

                          90
                  ....*....|
gi 2527434832 360 LTKYD-VHRV 368
Cdd:pfam13524  79 LAEHTyAHRA 88
GT4_WbaZ-like cd03804
mannosyltransferase WbaZ and similar proteins; This family is most closely related to the GT4 ...
 296-349 1.31e-06

mannosyltransferase WbaZ and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. WbaZ in Salmonella enterica has been shown to possess mannosyltransferase activity.


Pssm-ID: 340833 [Multi-domain]  Cd Length: 356  Bit Score: 49.98  E-value: 1.31e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2527434832 296 LEAMAMGRAVITTDAPGCRETVIEGENGHLVAVKSVDALVNAMQQCIDQPARVE 349
Cdd:cd03804   282 VEAQACGTPVIAFGKGGALETVRPGPTGILFGEQTVESLKAAVEEFEQNFDRFK 335
PRK09922 PRK09922
lipopolysaccharide 1,6-galactosyltransferase;
193-344 1.41e-06

lipopolysaccharide 1,6-galactosyltransferase;


Pssm-ID: 182148 [Multi-domain]  Cd Length: 359  Bit Score: 49.71  E-value: 1.41e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832 193 LPRQANGQPKVaFLLIARLL--GDKGVREyaaAAAKIKATYPEIEFHLVGwidqnpSAIDQKELDQWVQE----QRVTYW 266
Cdd:PRK09922  172 IPPPERDKPAV-FLYVGRLKfeGQKNVKE---LFDGLSQTTGEWQLHIIG------DGSDFEKCKAYSRElgieQRIIWH 241

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832 267 GKLKD----VRPAIAATSVYVLPSYREGTPRTVLEAMAMGRAVITTDAP-GCRETVIEGENGHLVAVKSVDALVNAMQQC 341
Cdd:PRK09922  242 GWQSQpwevVQQKIKNVSALLLTSKFEGFPMTLLEAMSYGIPCISSDCMsGPRDIIKPGLNGELYTPGNIDEFVGKLNKV 321


                  ...
gi 2527434832 342 IDQ 344
Cdd:PRK09922  322 ISG 324
PRK15179 PRK15179
Vi polysaccharide biosynthesis protein TviE; Provisional
 261-374 2.39e-06

Vi polysaccharide biosynthesis protein TviE; Provisional


Pssm-ID: 185101 [Multi-domain]  Cd Length: 694  Bit Score: 49.65  E-value: 2.39e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832 261 QRVTYWgklkdvrpaIAATSVYVLPSYREGTPRTVLEAMAMGRAVITTDAPGCRETVIEGENGHLVAVKSVDA--LVNAM 338
Cdd:PRK15179  583 RRVGYW---------LTQFNAFLLLSRFEGLPNVLIEAQFSGVPVVTTLAGGAGEAVQEGVTGLTLPADTVTApdVAEAL 653

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 2527434832 339 QQCIDQPARVEDMGQRSREIALTKYDVHRVNAHMLT 374
Cdd:PRK15179  654 ARIHDMCAADPGIARKAADWASARFSLNQMIASTVR 689
GT4_trehalose_phosphorylase cd03792
trehalose phosphorylase and similar proteins; Trehalose phosphorylase (TP) reversibly ...
 277-357 2.89e-06

trehalose phosphorylase and similar proteins; Trehalose phosphorylase (TP) reversibly catalyzes trehalose synthesis and degradation from alpha-glucose-1-phosphate (alpha-Glc-1-P) and glucose. The catalyzing activity includes the phosphorolysis of trehalose, which produce alpha-Glc-1-P and glucose, and the subsequent synthesis of trehalose. This family is most closely related to the GT4 family of glycosyltransferases.


Pssm-ID: 340823 [Multi-domain]  Cd Length: 378  Bit Score: 48.86  E-value: 2.89e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832 277 AATSVYVLPSYREGTPRTVLEAMAMGRAVITTDAPGCRETVIEGENGHLVAvkSVDALVNAMQQCIDQPARVEDMGQRSR 356
Cdd:cd03792   278 RAATVVLQLSTREGFGLTVSEALWKGKPVIATPAGGIPLQVIDGETGFLVN--SVEGAAVRILRLLTDPELRRKMGLAAR 355


                  .
gi 2527434832 357 E 357
Cdd:cd03792   356 E 356
GT4_WfcD-like cd03795
Escherichia coli alpha-1,3-mannosyltransferase WfcD and similar proteins; This family is most ...
 261-368 2.90e-06

Escherichia coli alpha-1,3-mannosyltransferase WfcD and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP-linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria and eukaryotes.


Pssm-ID: 340826 [Multi-domain]  Cd Length: 355  Bit Score: 48.81  E-value: 2.90e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832 261 QRVTYWGKLKDVRPAI--AATSVYVLPSY--REGTPRTVLEAMAMGRAVITTDAP-GCRETVIEGENGHLVAVKSVDALV 335
Cdd:cd03795   242 DNVKFLGRVDDEEKVIylHLCDVFVFPSVlrSEAFGIVLLEAMMCGKPVISTNIGtGVPYVNNNGETGLVVPPKDPDALA 321

                          90       100       110
                  ....*....|....*....|....*....|...
gi 2527434832 336 NAMQQCIDQPARVEDMGQRSREIALTKYDVHRV 368
Cdd:cd03795   322 EAIDKLLSDEELRESYGENAKKRFEELFTAEKM 354
PLN02871 PLN02871
UDP-sulfoquinovose:DAG sulfoquinovosyltransferase
 252-364 1.44e-05

UDP-sulfoquinovose:DAG sulfoquinovosyltransferase


Pssm-ID: 215469 [Multi-domain]  Cd Length: 465  Bit Score: 47.01  E-value: 1.44e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832 252 KELDQWVQEQRVTYWGKLK--DVRPAIAATSVYVLPSYREGTPRTVLEAMAMGRAVITTDAPGCRETV---IEGENGHLV 326
Cdd:PLN02871  303 EELEKMFAGTPTVFTGMLQgdELSQAYASGDVFVMPSESETLGFVVLEAMASGVPVVAARAGGIPDIIppdQEGKTGFLY 382

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 2527434832 327 AVKSVDALVNAMQQCIDQPARVEDMGQRSREiALTKYD 364
Cdd:PLN02871  383 TPGDVDDCVEKLETLLADPELRERMGAAARE-EVEKWD 419
GT4_ALG2-like cd03805
alpha-1,3/1,6-mannosyltransferase ALG2 and similar proteins; This family is most closely ...
 296-366 4.60e-05

alpha-1,3/1,6-mannosyltransferase ALG2 and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. ALG2, a 1,3-mannosyltransferase, in yeast catalyzes the mannosylation of Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate. A deficiency of this enzyme causes an abnormal accumulation of Man1GlcNAc2-PP-dolichol and Man2GlcNAc2-PP-dolichol, which is associated with a type of congenital disorders of glycosylation (CDG), designated CDG-Ii, in humans.


Pssm-ID: 340834 [Multi-domain]  Cd Length: 392  Bit Score: 45.27  E-value: 4.60e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2527434832 296 LEAMAMGRAVITTDAPGCRETVIEGENGHLVAvKSVDALVNAMQQCIDQPARVEDMGQRSREIALTKYDVH 366
Cdd:cd03805   317 LEAMYAGKPVIACNSGGPLETVVEGVTGFLCE-PTPEAFAEAMLKLANDPDLADRMGAAGRKRVKEKFSRE 386
GT4_mannosyltransferase-like cd03822
mannosyltransferases of glycosyltransferase family 4 and similar proteins; This family is most ...
 139-359 6.28e-05

mannosyltransferases of glycosyltransferase family 4 and similar proteins; This family is most closely related to the GT1 family of glycosyltransferases. ORF704 in E. coli has been shown to be involved in the biosynthesis of O-specific mannose homopolysaccharides.


Pssm-ID: 340849 [Multi-domain]  Cd Length: 370  Bit Score: 44.68  E-value: 6.28e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832 139 HSLYKKALTYSDKVFFQNPDDLALFRHMNLIERNKPAVVVNGSGIdlAKFDQVElPRQANGQPKVAFLLIA-RLLGD-KG 216
Cdd:cd03822   125 LKVLFRIATLSERVVVMAPISRFLLVRIKLIPAVNIEVIPHGVPE--VPQDPTT-ALKRLLLPEGKKVILTfGFIGPgKG 201

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832 217 VREYAAAAAKIKATYPEIEFHLVGWIDQNPSAiDQKELDQWVQEQR-------VTYWGKL--KDVRPAIAATSVYVLPsY 287
Cdd:cd03822   202 LEILLEALPELKAEFPDVRLVIAGELHPSLAR-YEGERYRKAAIEElglqdhvDFHNNFLpeEEVPRYISAADVVVLP-Y 279

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2527434832 288 RE---GTPRTVLEAMAMGRAVITTDAPGCRETVIEGEnGHLVAVKSVDALVNAMQQCIDQPARVEDMGQRSREIA 359
Cdd:cd03822   280 LNteqSSSGTLSYAIACGKPVISTPLRHAEELLADGR-GVLVPFDDPSAIAEAILRLLEDDERRQAIAERAYAYA 353
GT4_AmsK-like cd04946
amylovoran biosynthesis glycosyltransferase AmsK and similar proteins; This family is most ...
 281-358 1.03e-04

amylovoran biosynthesis glycosyltransferase AmsK and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. AmsK is involved in the biosynthesis of amylovoran, which functions as a virulence factor. It functions as a glycosyl transferase which transfers galactose from UDP-galactose to a lipid-linked amylovoran-subunit precursor. The members of this family are found mainly in bacteria and Archaea.


Pssm-ID: 340854 [Multi-domain]  Cd Length: 401  Bit Score: 43.99  E-value: 1.03e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527434832 281 VYVLPSYREGTPRTVLEAMAMGRAVITTDAPGCRETVIEGENGHLVavkSVDALVNAMQQCI----DQPARVEDMGQRSR 356
Cdd:cd04946   307 VFVNVSESEGIPVSIMEAISFGIPVIATNVGGTREIVENETNGLLL---DKDPTPNEIVSSImkfyLDGGDYKTMKISAR 383


                  ..
gi 2527434832 357 EI 358
Cdd:cd04946   384 EC 385
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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