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Conserved domains on  [gi|2528006379|ref|WP_288957378|]
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APC family permease [uncultured Thomasclavelia sp.]

Protein Classification

APC family permease( domain architecture ID 11425014)

APC (amino acid/polyamine/organocation) family permease is involved in the uptake of a specific amino acid and/or polyamine substrate with the concomitant import of a proton

Gene Ontology:  GO:0016020|GO:0055085|GO:0022857|GO:0015171|GO:0006865
PubMed:  23177982|24038584|25043943|10931886
SCOP:  4006243
TCDB:  2.A.3.1|2.A.3

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PotE COG0531
Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
10-430 4.30e-45

Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];


:

Pssm-ID: 440297 [Multi-domain]  Cd Length: 438  Bit Score: 162.37  E-value: 4.30e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528006379  10 KKYGLFTAITMIVGICIGSGIFFKSDNVLIATNGSIalgVLSFILAAISIIFGCLTIGELASRTDKVGGLISYAEMFLTR 89
Cdd:COG0531    11 RKLGLFDLVALGVGAIIGAGIFVLPGLAAGLAGPAA---ILAWLIAGLLALLVALSYAELASAFPRAGGAYTYARRALGP 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528006379  90 KVACAMGWFQtFVYYPTITSVVAWVIGVYINILFNLQASlefeILIGYIFLLLCFVYNILLPKFGAFIQNSTTLIKLLPL 169
Cdd:COG0531    88 LLGFLAGWAL-LLSYVLAVAAVAVAFGGYLSSLFPAGGS----VLIALVLILLLTLLNLRGVKESAKVNNILTVLKLLVL 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528006379 170 FILGILGIIFGDPINgLANTSINTLNGTGWISALGPIAYSFDGWIVTTSISHELKDAKKNMPKALMLGPLIVLSIYVLYF 249
Cdd:COG0531   163 LLFIVVGLFAFDPAN-FTPFLPAGGGLSGVLAALALAFFAFTGFEAIANLAEEAKNPKRNIPRAIILSLLIVGVLYILVS 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528006379 250 IGISCYVTPEVVMTLGDrHVSLAAQNLFGPAFSKMIIIFIVISVIGTVNGLVIGYIRMPYSLSlRKNMFPfsKHLRKIDK 329
Cdd:COG0531   242 LALTGVVPYDELAASGA-PLADAAEAVFGPWGAILIALGALLSLLGALNASILGASRLLYAMA-RDGLLP--KVFAKVHP 317

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528006379 330 RFQMPLNSAICSLIICTIWMFVhyLCTKYNLLYNsdVSEGAIGISYIFYTLLYIRVFKMYLDKEIKSKFKGLVCPILATI 409
Cdd:COG0531   318 RFGTPVNAILLTGVIALLLLLL--GAASFTALAS--LASVGVLLAYLLVALAVIVLRRRRPDLPRPFRVPLPLIPILGIL 393

                         410       420
                  ....*....|....*....|.
gi 2528006379 410 GSLIILSGGIQNKLFIFYIIF 430
Cdd:COG0531   394 LCLFLLYLLGPGALLIGLVLL 414
 
Name Accession Description Interval E-value
PotE COG0531
Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
10-430 4.30e-45

Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];


Pssm-ID: 440297 [Multi-domain]  Cd Length: 438  Bit Score: 162.37  E-value: 4.30e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528006379  10 KKYGLFTAITMIVGICIGSGIFFKSDNVLIATNGSIalgVLSFILAAISIIFGCLTIGELASRTDKVGGLISYAEMFLTR 89
Cdd:COG0531    11 RKLGLFDLVALGVGAIIGAGIFVLPGLAAGLAGPAA---ILAWLIAGLLALLVALSYAELASAFPRAGGAYTYARRALGP 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528006379  90 KVACAMGWFQtFVYYPTITSVVAWVIGVYINILFNLQASlefeILIGYIFLLLCFVYNILLPKFGAFIQNSTTLIKLLPL 169
Cdd:COG0531    88 LLGFLAGWAL-LLSYVLAVAAVAVAFGGYLSSLFPAGGS----VLIALVLILLLTLLNLRGVKESAKVNNILTVLKLLVL 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528006379 170 FILGILGIIFGDPINgLANTSINTLNGTGWISALGPIAYSFDGWIVTTSISHELKDAKKNMPKALMLGPLIVLSIYVLYF 249
Cdd:COG0531   163 LLFIVVGLFAFDPAN-FTPFLPAGGGLSGVLAALALAFFAFTGFEAIANLAEEAKNPKRNIPRAIILSLLIVGVLYILVS 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528006379 250 IGISCYVTPEVVMTLGDrHVSLAAQNLFGPAFSKMIIIFIVISVIGTVNGLVIGYIRMPYSLSlRKNMFPfsKHLRKIDK 329
Cdd:COG0531   242 LALTGVVPYDELAASGA-PLADAAEAVFGPWGAILIALGALLSLLGALNASILGASRLLYAMA-RDGLLP--KVFAKVHP 317

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528006379 330 RFQMPLNSAICSLIICTIWMFVhyLCTKYNLLYNsdVSEGAIGISYIFYTLLYIRVFKMYLDKEIKSKFKGLVCPILATI 409
Cdd:COG0531   318 RFGTPVNAILLTGVIALLLLLL--GAASFTALAS--LASVGVLLAYLLVALAVIVLRRRRPDLPRPFRVPLPLIPILGIL 393

                         410       420
                  ....*....|....*....|.
gi 2528006379 410 GSLIILSGGIQNKLFIFYIIF 430
Cdd:COG0531   394 LCLFLLYLLGPGALLIGLVLL 414
AA_permease_2 pfam13520
Amino acid permease;
13-432 1.56e-26

Amino acid permease;


Pssm-ID: 404414 [Multi-domain]  Cd Length: 427  Bit Score: 110.86  E-value: 1.56e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528006379  13 GLFTAITMIVGICIGSGIFFKSDnvliATNGSIALGVLSFILAAISIIFGCLTIGELASRTDKVGGLISYAEMFLTRKVA 92
Cdd:pfam13520   2 GLLSAFALVIGSVIGSGIFVAPL----VASGGPALIVWGWIAAIIFSLAVGLVYAELSSALPRSGGIYVYLENAFGKFVA 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528006379  93 CAMGWFQTFVYYPTITSVVAWVIGVYINILF-NLQASLEFEILIGYIFLLLCFVYNILLPKFGAFIQNSTTLIKL-LPLF 170
Cdd:pfam13520  78 FLAGWSNWFAYVLGLASSASVAASYLLSALGpDLVPTTWLTYGIAIAILIIFAIINIRGVRESAKIQNILGILKLlLPLI 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528006379 171 ILGILGIIFGD----PINGLANTSINTLNGTGWISALGPIAYSFDGWIVTTSISHELKdaKKNMPKALMLGPLIVLSIYV 246
Cdd:pfam13520 158 LIIILGLVTADgggfNLLSGEWHTFFPDGWPGVFAGFLGVLWSFTGFESAANVSEEVK--KRNVPKAIFIGVIIVGVLYI 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528006379 247 LYFIGISCYVTPEVVMTLGDRH--VSLAAQNLFGPAFSKMIIIFIVISVIGTVNGLVIGYIRMPYSLSlRKNMFPFSKHL 324
Cdd:pfam13520 236 LVNIAFFGVVPDDEIALSSGLGqvAALLFQAVGGKWGAIIVVILLALSLLGAVNTAIVGASRLLYALA-RDGVLPFSRFF 314

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528006379 325 RKIDKrFQMPLNSAICSLIICTIWMFvhyLCTKYNLLYNSDVSEGAIGIsYIFYTLLYIRVFKMYLDKEIKSKFKG---- 400
Cdd:pfam13520 315 AKVNK-FGSPIRAIILTAILSLILLL---LFLLSPAAYNALLSLSAYGY-LLSYLLPIIGLLILRKKRPDLGRIPGrwpv 389

                         410       420       430
                  ....*....|....*....|....*....|....*
gi 2528006379 401 ---LVCPILATIGSLIILSGGIQNKLFIFYIIFCI 432
Cdd:pfam13520 390 aifGILFSLFLIVALFFPPVGPATGSSLNYAIILI 424
2A0308 TIGR00911
L-type amino acid transporter; [Transport and binding proteins, Amino acids, peptides and ...
 10-349 1.17e-17

L-type amino acid transporter; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273332 [Multi-domain]  Cd Length: 501  Bit Score: 85.18  E-value: 1.17e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528006379  10 KKYGLFTAITMIVGICIGSGIFFKSDNVLIATnGSIALGVLSFILAAISIIFGCLTIGELASRTDKVGGLISYAEMFLTR 89
Cdd:TIGR00911  42 KEITLLSGVGIIVGTIIGSGIFVSPKGVLKNA-GSVGLALIMWAVCGIFSIVGALVYAELGTTIPKSGGEYNYILEVFGP 120

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528006379  90 KVACAMGWFQTFVYYPTITSVVAWVIGVYINILFNLQASLEFEI--LIGYIFLLLCFVYNILLPKFGAFIQNSTTLIKLL 167
Cdd:TIGR00911 121 LLAFLRLWIELLVIRPGSQAVNALNFAIYILTPVFPDCEVPEWAirLVAVLCVLLLTLVNCLSVKWATRVQDIFTACKLL 200

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528006379 168 PLFILGILGIIF--------GDPINGLANTSintLNGTGWISALGPIAYSFDGWIVTTSISHELKDAKKNMPKALMLGPL 239
Cdd:TIGR00911 201 ALLLIIITGWVQlgkggvesLNPKNAFEGTE---TSAGGIVLAFYSGIWAYGGWNYLNFVTEEVKNPYRTLPIAIIISMP 277

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528006379 240 IVLSIYVLYFIGISCYVTPE-------VVMTLGDRHVSLAAqnLFGPAFSKMiiifiviSVIGTVNGLVIGYIRMPYSLS 312
Cdd:TIGR00911 278 IVTFIYVLTNIAYFTVLSPEellaslaVAVDFGERLLGVMS--WAMPALVGL-------SCFGSVNGSLFSSSRLFFVGG 348

                         330       340       350
                  ....*....|....*....|....*....|....*..
gi 2528006379 313 lRKNMFPFSKHLRKIDkrfqmPLNSAICSLIICTIWM 349
Cdd:TIGR00911 349 -REGHLPSLLSMIHVK-----RLTPLPSLLIVCTLTL 379
frlA PRK11357
amino acid permease;
6-348 1.51e-14

amino acid permease;


Pssm-ID: 183096 [Multi-domain]  Cd Length: 445  Bit Score: 75.28  E-value: 1.51e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528006379   6 NDVTKKYGLFTAITMIVGICIGSGIFFKSDNVLIATnGSIALGVLSFILAAISIIFGCLTIGELASRTDKVGGLISYAEM 85
Cdd:PRK11357    4 QELQRKLGFWAVLAIAVGTTVGSGIFVSVGEVAKAA-GTPWLTVLAFVIGGLIVIPQMCVYAELSTAYPENGADYVYLKN 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528006379  86 FLTRKVACAMGWFQTFVYYPTITSVVAWVIGVYINILFNLQASLEFEILIGYIFLLLcfVYNILLPKFGAFIQNSTTLIK 165
Cdd:PRK11357   83 AGSRPLAFLSGWASFWANDAPSLSIMALAIVSNLGFLTPIDPLLGKFIAAGLIIAFM--LLHLRSVEGGAAFQTLITIAK 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528006379 166 LLPLFILGILGIIF--GDPINGLANTSIN-TLNGTGWISALGPIAYSFDGWIVTTSISHELKDAKKNMPKALMLGPLIVL 242
Cdd:PRK11357  161 IIPFTIVIGLGIFWfkAENFAAPTTTAIGaTGSFMALLAGISATSWSYTGMASICYMTGEIKNPGKTMPRALIGSCLLVL 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528006379 243 SIYVLYFIGISCYVtPEVVMTLGDRHVSLAAQNL--FGPAFSKMIIIFIVISVIGTVNGLVIGYIRMPYSLSlRKNMfpF 320
Cdd:PRK11357  241 VLYTLLALVISGLM-PFDKLANSETPISDALTWIpaLGSTAGIFVAITAMIVILGSLSSCVMYQPRLEYAMA-KDNL--F 316

                         330       340       350
                  ....*....|....*....|....*....|
gi 2528006379 321 SKHLRKIDKRFQMPLNSAI--CSLIICTIW 348
Cdd:PRK11357  317 FKCFGHVHPKYNTPDVSIIlqGALGIFFIF 346
 
Name Accession Description Interval E-value
PotE COG0531
Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
10-430 4.30e-45

Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];


Pssm-ID: 440297 [Multi-domain]  Cd Length: 438  Bit Score: 162.37  E-value: 4.30e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528006379  10 KKYGLFTAITMIVGICIGSGIFFKSDNVLIATNGSIalgVLSFILAAISIIFGCLTIGELASRTDKVGGLISYAEMFLTR 89
Cdd:COG0531    11 RKLGLFDLVALGVGAIIGAGIFVLPGLAAGLAGPAA---ILAWLIAGLLALLVALSYAELASAFPRAGGAYTYARRALGP 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528006379  90 KVACAMGWFQtFVYYPTITSVVAWVIGVYINILFNLQASlefeILIGYIFLLLCFVYNILLPKFGAFIQNSTTLIKLLPL 169
Cdd:COG0531    88 LLGFLAGWAL-LLSYVLAVAAVAVAFGGYLSSLFPAGGS----VLIALVLILLLTLLNLRGVKESAKVNNILTVLKLLVL 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528006379 170 FILGILGIIFGDPINgLANTSINTLNGTGWISALGPIAYSFDGWIVTTSISHELKDAKKNMPKALMLGPLIVLSIYVLYF 249
Cdd:COG0531   163 LLFIVVGLFAFDPAN-FTPFLPAGGGLSGVLAALALAFFAFTGFEAIANLAEEAKNPKRNIPRAIILSLLIVGVLYILVS 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528006379 250 IGISCYVTPEVVMTLGDrHVSLAAQNLFGPAFSKMIIIFIVISVIGTVNGLVIGYIRMPYSLSlRKNMFPfsKHLRKIDK 329
Cdd:COG0531   242 LALTGVVPYDELAASGA-PLADAAEAVFGPWGAILIALGALLSLLGALNASILGASRLLYAMA-RDGLLP--KVFAKVHP 317

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528006379 330 RFQMPLNSAICSLIICTIWMFVhyLCTKYNLLYNsdVSEGAIGISYIFYTLLYIRVFKMYLDKEIKSKFKGLVCPILATI 409
Cdd:COG0531   318 RFGTPVNAILLTGVIALLLLLL--GAASFTALAS--LASVGVLLAYLLVALAVIVLRRRRPDLPRPFRVPLPLIPILGIL 393

                         410       420
                  ....*....|....*....|.
gi 2528006379 410 GSLIILSGGIQNKLFIFYIIF 430
Cdd:COG0531   394 LCLFLLYLLGPGALLIGLVLL 414
AA_permease_2 pfam13520
Amino acid permease;
13-432 1.56e-26

Amino acid permease;


Pssm-ID: 404414 [Multi-domain]  Cd Length: 427  Bit Score: 110.86  E-value: 1.56e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528006379  13 GLFTAITMIVGICIGSGIFFKSDnvliATNGSIALGVLSFILAAISIIFGCLTIGELASRTDKVGGLISYAEMFLTRKVA 92
Cdd:pfam13520   2 GLLSAFALVIGSVIGSGIFVAPL----VASGGPALIVWGWIAAIIFSLAVGLVYAELSSALPRSGGIYVYLENAFGKFVA 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528006379  93 CAMGWFQTFVYYPTITSVVAWVIGVYINILF-NLQASLEFEILIGYIFLLLCFVYNILLPKFGAFIQNSTTLIKL-LPLF 170
Cdd:pfam13520  78 FLAGWSNWFAYVLGLASSASVAASYLLSALGpDLVPTTWLTYGIAIAILIIFAIINIRGVRESAKIQNILGILKLlLPLI 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528006379 171 ILGILGIIFGD----PINGLANTSINTLNGTGWISALGPIAYSFDGWIVTTSISHELKdaKKNMPKALMLGPLIVLSIYV 246
Cdd:pfam13520 158 LIIILGLVTADgggfNLLSGEWHTFFPDGWPGVFAGFLGVLWSFTGFESAANVSEEVK--KRNVPKAIFIGVIIVGVLYI 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528006379 247 LYFIGISCYVTPEVVMTLGDRH--VSLAAQNLFGPAFSKMIIIFIVISVIGTVNGLVIGYIRMPYSLSlRKNMFPFSKHL 324
Cdd:pfam13520 236 LVNIAFFGVVPDDEIALSSGLGqvAALLFQAVGGKWGAIIVVILLALSLLGAVNTAIVGASRLLYALA-RDGVLPFSRFF 314

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528006379 325 RKIDKrFQMPLNSAICSLIICTIWMFvhyLCTKYNLLYNSDVSEGAIGIsYIFYTLLYIRVFKMYLDKEIKSKFKG---- 400
Cdd:pfam13520 315 AKVNK-FGSPIRAIILTAILSLILLL---LFLLSPAAYNALLSLSAYGY-LLSYLLPIIGLLILRKKRPDLGRIPGrwpv 389

                         410       420       430
                  ....*....|....*....|....*....|....*
gi 2528006379 401 ---LVCPILATIGSLIILSGGIQNKLFIFYIIFCI 432
Cdd:pfam13520 390 aifGILFSLFLIVALFFPPVGPATGSSLNYAIILI 424
2A0308 TIGR00911
L-type amino acid transporter; [Transport and binding proteins, Amino acids, peptides and ...
 10-349 1.17e-17

L-type amino acid transporter; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273332 [Multi-domain]  Cd Length: 501  Bit Score: 85.18  E-value: 1.17e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528006379  10 KKYGLFTAITMIVGICIGSGIFFKSDNVLIATnGSIALGVLSFILAAISIIFGCLTIGELASRTDKVGGLISYAEMFLTR 89
Cdd:TIGR00911  42 KEITLLSGVGIIVGTIIGSGIFVSPKGVLKNA-GSVGLALIMWAVCGIFSIVGALVYAELGTTIPKSGGEYNYILEVFGP 120

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528006379  90 KVACAMGWFQTFVYYPTITSVVAWVIGVYINILFNLQASLEFEI--LIGYIFLLLCFVYNILLPKFGAFIQNSTTLIKLL 167
Cdd:TIGR00911 121 LLAFLRLWIELLVIRPGSQAVNALNFAIYILTPVFPDCEVPEWAirLVAVLCVLLLTLVNCLSVKWATRVQDIFTACKLL 200

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528006379 168 PLFILGILGIIF--------GDPINGLANTSintLNGTGWISALGPIAYSFDGWIVTTSISHELKDAKKNMPKALMLGPL 239
Cdd:TIGR00911 201 ALLLIIITGWVQlgkggvesLNPKNAFEGTE---TSAGGIVLAFYSGIWAYGGWNYLNFVTEEVKNPYRTLPIAIIISMP 277

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528006379 240 IVLSIYVLYFIGISCYVTPE-------VVMTLGDRHVSLAAqnLFGPAFSKMiiifiviSVIGTVNGLVIGYIRMPYSLS 312
Cdd:TIGR00911 278 IVTFIYVLTNIAYFTVLSPEellaslaVAVDFGERLLGVMS--WAMPALVGL-------SCFGSVNGSLFSSSRLFFVGG 348

                         330       340       350
                  ....*....|....*....|....*....|....*..
gi 2528006379 313 lRKNMFPFSKHLRKIDkrfqmPLNSAICSLIICTIWM 349
Cdd:TIGR00911 349 -REGHLPSLLSMIHVK-----RLTPLPSLLIVCTLTL 379
frlA PRK11357
amino acid permease;
6-348 1.51e-14

amino acid permease;


Pssm-ID: 183096 [Multi-domain]  Cd Length: 445  Bit Score: 75.28  E-value: 1.51e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528006379   6 NDVTKKYGLFTAITMIVGICIGSGIFFKSDNVLIATnGSIALGVLSFILAAISIIFGCLTIGELASRTDKVGGLISYAEM 85
Cdd:PRK11357    4 QELQRKLGFWAVLAIAVGTTVGSGIFVSVGEVAKAA-GTPWLTVLAFVIGGLIVIPQMCVYAELSTAYPENGADYVYLKN 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528006379  86 FLTRKVACAMGWFQTFVYYPTITSVVAWVIGVYINILFNLQASLEFEILIGYIFLLLcfVYNILLPKFGAFIQNSTTLIK 165
Cdd:PRK11357   83 AGSRPLAFLSGWASFWANDAPSLSIMALAIVSNLGFLTPIDPLLGKFIAAGLIIAFM--LLHLRSVEGGAAFQTLITIAK 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528006379 166 LLPLFILGILGIIF--GDPINGLANTSIN-TLNGTGWISALGPIAYSFDGWIVTTSISHELKDAKKNMPKALMLGPLIVL 242
Cdd:PRK11357  161 IIPFTIVIGLGIFWfkAENFAAPTTTAIGaTGSFMALLAGISATSWSYTGMASICYMTGEIKNPGKTMPRALIGSCLLVL 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528006379 243 SIYVLYFIGISCYVtPEVVMTLGDRHVSLAAQNL--FGPAFSKMIIIFIVISVIGTVNGLVIGYIRMPYSLSlRKNMfpF 320
Cdd:PRK11357  241 VLYTLLALVISGLM-PFDKLANSETPISDALTWIpaLGSTAGIFVAITAMIVILGSLSSCVMYQPRLEYAMA-KDNL--F 316

                         330       340       350
                  ....*....|....*....|....*....|
gi 2528006379 321 SKHLRKIDKRFQMPLNSAI--CSLIICTIW 348
Cdd:PRK11357  317 FKCFGHVHPKYNTPDVSIIlqGALGIFFIF 346
AA_permease pfam00324
Amino acid permease;
26-377 4.72e-13

Amino acid permease;


Pssm-ID: 366028 [Multi-domain]  Cd Length: 467  Bit Score: 70.81  E-value: 4.72e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528006379  26 IGSGIFFKSDNVLIatNGSIALGVLSFILAAISIIFGCLTIGELASRTDKVGGLISYAEMFLTRKVACAMGWFQTFVYYP 105
Cdd:pfam00324  11 IGTGLFVGSGSVLG--QAGPAGALLGYLISGVVIFLVMLSLGEISTNGPVSGGFYTYASRFLGPSLGFATGWNYWLSWIT 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528006379 106 TITSVVAWVIGVYINILFNLQASLEFeiLIGYIFLLLCFVYNILLPKFGAFIQNSTTLIKLLPLFILGILGIIFGDPING 185
Cdd:pfam00324  89 VLALELTAASILIQFWELVPDIPYLW--VWGAVFLVLLTIINLVGVKWYGEAEFWFALIKIIAIIGFIIVGIILLSGGNP 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528006379 186 LA---------NTSINTL---NGTGWISALGPIAYSFDGWIVTTSISHELKDAKKNMPKALMLGPLIVLSIYVLYFIGIS 253
Cdd:pfam00324 167 NDgaifrylgdNGGKNNFppgFGKGFISVFVIAFFAFTGIELVGIAAGEVKNPEKSIPKAILQVIWRITIFYILSLLAIG 246

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528006379 254 CYVTPEVVMTLGDRHVSLAAQNLFG-----PAFSKMIIIFIVISVIGTVNGLVIGYIRMPYSLSlRKNMFPfsKHLRKID 328
Cdd:pfam00324 247 LLVPWNDPGLLNDSASAASPFVIFFkflgiSGLAPLINAVILTAALSAANSSLYSGSRMLYSLA-RDGLAP--KFLKKVD 323

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*....
gi 2528006379 329 KRfqmplNSAICSLIICTIWMFVHYLCTKYNLLYNSDVSEGAIGISYIF 377
Cdd:pfam00324 324 KR-----GVPLRAILVSMVISLLALLLASLNPAIVFNFLLAISGLSGLI 367
PRK10644 PRK10644
arginine/agmatine antiporter;
9-247 4.02e-09

arginine/agmatine antiporter;


Pssm-ID: 182613 [Multi-domain]  Cd Length: 445  Bit Score: 58.26  E-value: 4.02e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528006379   9 TKKYGLFTAITMIVGICIGSGIFFKSDNvLIATNGSIALGVLSFILAAISIifgCLTIGELASRTDKVGGLISYAEmflt 88
Cdd:PRK10644    7 AHKVGLIPVTLMVAGNIMGSGVFLLPAN-LASTGGIAIYGWLVTIIGALGL---SMVYAKMSSLDPSPGGSYAYAR---- 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528006379  89 RKVACAMGwFQTFVYY---PTITSVVAWVIGV-YINILFN-LQASLEFEILIgyIFLLLCFVY-NILLPKFGAFIQNSTT 162
Cdd:PRK10644   79 RCFGPFLG-YQTNVLYwlaCWIGNIAMVVIGVgYLSYFFPiLKDPLVLTITC--VVVLWIFVLlNIVGPKMITRVQAVAT 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528006379 163 LIKLLPLFILGILGIIFGDPINGLANTSINTLNGTGWI-SALGPIAYSFDGWIVTTSISHELKDAKKNMPKALMLGPLIV 241
Cdd:PRK10644  156 VLALIPIVGIAVFGWFWFRGETYMAAWNVSGLGTFGAIqSTLNVTLWSFIGVESASVAAGVVKNPKRNVPIATIGGVLIA 235


                  ....*.
gi 2528006379 242 LSIYVL 247
Cdd:PRK10644  236 AVCYVL 241
2A0303 TIGR00906
cationic amino acid transport permease; [Transport and binding proteins, Amino acids, peptides ...
 22-351 8.32e-06

cationic amino acid transport permease; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273330 [Multi-domain]  Cd Length: 557  Bit Score: 48.27  E-value: 8.32e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528006379  22 VGICIGSGIFFKSDNVliATNGSIALGVLSFILAAISIIFGCLTIGELASRTDKVGGLISYAEMFLTRKVACAMGWfQTF 101
Cdd:TIGR00906  40 IGSTIGAGIYVLTGEV--ARNDSGPAIVLSFLISGLAAVLSGFCYAEFGARVPKAGSAYLYSYVTVGELWAFITGW-NLI 116

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528006379 102 VYYPTITSVVAWVIGVYINILFNLQASLEFEILIG-----------YIFLLLCFVYNILLP---KFGAFIQNSTTLIKLL 167
Cdd:TIGR00906 117 LEYVIGTAAVARSWSAYFDELLNKQIGQFRRTYFKlnydglaeypdFFAVCLILLLAVLLSfgvKESAWVNKIFTAINIL 196

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528006379 168 PLFILGILGIIFGDpingLANTSINTLNG---------TGWISALGPIAYSFDGWIVTTSISHELKDAKKNMPKALmLGP 238
Cdd:TIGR00906 197 VLLFVIIAGFTKAD----VANWSITEEKGaggfmpygfTGVLSGAATCFFAFIGFDAIATTGEEVKNPQRAIPIGI-VTS 271

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528006379 239 LIVLSIyvlyfigisCYVTPEVVMTLGDRHVSLAAQNLFGPAFSKM-----IIIFIVISVIGTVNGLVIGYIRMP---YS 310
Cdd:TIGR00906 272 LLVCFV---------AYFLMSAALTLMMPYYLLDPDAPFPVAFEYVgwdpaKYIVAVGALCGMSTSLLGGMFPLPrviYA 342

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|.
gi 2528006379 311 LSLRKNMFPFskhLRKIDKRFQMPLNSAICSLIICTIWMFV 351
Cdd:TIGR00906 343 MARDGLLFKW---LAQINSKTKTPINATVVSGAIAALMAFL 380
LysP COG0833
Amino acid permease [Amino acid transport and metabolism];
18-250 7.62e-04

Amino acid permease [Amino acid transport and metabolism];


Pssm-ID: 440595 [Multi-domain]  Cd Length: 467  Bit Score: 41.70  E-value: 7.62e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528006379  18 ITMI-VGICIGSGIFFKSDNVlIATNGsiALG-VLSFILAAISIIFGCLTIGELASRTDKVGGLISYAEMFLTRKVACAM 95
Cdd:COG0833    19 LSMIaLGGVIGTGLFLASGYT-ISQAG--PGGaLLAYLLGGLMVYFLMTSLGELAVAMPVSGSFQTYATRFIDPAFGFAV 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528006379  96 GWFQTFvyyptitsvvAWVIGVyinilfnlqaSLEF---EILIGY------------IFLLLCFVYNILLPKFGAFIQNS 160
Cdd:COG0833    96 GWNYWL----------NWAITV----------AAELtaaGIIMQYwfpdvpvwiwslLFLALIFLLNALSVKAFGESEFW 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528006379 161 TTLIKLLP--LFI----LGILGIIFGDPInGLANTSINT---LNG-TGWISALGPIAYSFDGWIVTTSISHELKDAKKNM 230
Cdd:COG0833   156 FSLIKVITviAFIivglLMIFGIIGGHAP-GFSNFTTGDgpfPGGfLAILGVMMIVGFSFQGTELIGIAAGESENPEKTI 234

                         250       260
                  ....*....|....*....|....*..
gi 2528006379 231 PKA-------LMLgpLIVLSIYVLYFI 250
Cdd:COG0833   235 PKAirqvfwrILL--FYILAIFVIAAL 259
PRK10836 PRK10836
lysine transporter; Provisional
 18-253 7.76e-04

lysine transporter; Provisional


Pssm-ID: 182767  Cd Length: 489  Bit Score: 41.73  E-value: 7.76e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528006379  18 ITMI-VGICIGSGIFFKSDNVLIATNGSIALgvLSFILAAISIIFGCLTIGELASRTDKVGGLISYAEMFLTRKVACAMG 96
Cdd:PRK10836   22 LTMIaIGGSIGTGLFVASGATISQAGPGGAL--LSYMLIGLMVYFLMTSLGELAAYMPVSGSFATYGQNYVEEGFGFALG 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528006379  97 WfqTFVYYPTITSVVAWVIGvyinilfNLQASLEFEILIGYI----FLLLCFVYNILLPK-FG------AFIQnSTTLIK 165
Cdd:PRK10836  100 W--NYWYNWAVTIAVDLVAA-------QLVMSWWFPDTPGWIwsalFLGVIFLLNYISVRgFGeaeywfSLIK-VTTVIV 169

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528006379 166 LLPLFILGILGIIFGDPINGLANTSINTLNGTGWISALGPIA----YSFDGWIVTTSISHELKDAKKNMPKALMLGPLIV 241
Cdd:PRK10836  170 FIIVGVLMIIGIFKGAEPAGWSNWTIGDAPFAGGFAAMIGVAmivgFSFQGTELIGIAAGESEDPAKNIPRAVRQVFWRI 249

                         250
                  ....*....|..
gi 2528006379 242 LSIYVLYFIGIS 253
Cdd:PRK10836  250 LLFYVFAILIIS 261
cadB PRK10435
cadaverine/lysine antiporter;
9-247 1.63e-03

cadaverine/lysine antiporter;


Pssm-ID: 182458  Cd Length: 435  Bit Score: 40.50  E-value: 1.63e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528006379   9 TKKYGLFTAITMIVGICIGSGIFFKSDNvlIATNGSIAlgVLSFILAAISIIFGCLTIGELASRTDKVGGLISYAEmflt 88
Cdd:PRK10435    4 AKKIGLFACTGVVAGNMMGSGIALLPAN--LASIGSIA--IWGWIISIIGAMSLAYVYARLATKNPQQGGPIAYAG---- 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528006379  89 rKVACAMGwFQTFVYYPTITsvvaWVIGVYINILFNLQASLEFEIL-------IGYIFLLLCFVYNILLPkfGAFIQNST 161
Cdd:PRK10435   76 -EISPAFG-FQTGVLYYHAN----WIGNLAIGITAVSYLSTFFPVLndpipagIACIAIVWVFTFVNMLG--GTWVSRLT 147

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528006379 162 TL---IKLLPLFILGILGIIFGDPINGLANTSI-NTLNGTGWISALGPIAYSFDGWIVTTSISHELKDAKKNMPKALMLG 237
Cdd:PRK10435  148 TIglvLVLIPVVGTAIVGWHWFDAATYAANWNTsDTTDGHAIIKSILLCLWAFVGVESAAVSTGMVKNPKRTVPLATMLG 227

                         250
                  ....*....|
gi 2528006379 238 PLIVLSIYVL 247
Cdd:PRK10435  228 TGLAGIIYIA 237
2A0310 TIGR00913
amino acid permease (yeast); [Transport and binding proteins, Amino acids, peptides and amines]
 18-256 1.73e-03

amino acid permease (yeast); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273334  Cd Length: 478  Bit Score: 40.73  E-value: 1.73e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528006379  18 ITMI-VGICIGSGIFFKSDNVLiATNGSIALgVLSFILAAISIIFGCLTIGELASRTDKVGGLIS-YAEMFLTRKVACAM 95
Cdd:TIGR00913   9 IQMIaLGGTIGTGLLVGSGTAL-ATGGPAGL-LIGYAIMGSIIYCVMQSLGEMATFYPVVSGSFAtYASRFVDPAFGFAV 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528006379  96 GW---FQTFVYYPTITSVVAWVIGvYINILFNLqaslefeiligYIFLLLCFVYNILLPKFGA-------FIQNSTTLIK 165
Cdd:TIGR00913  87 GWnywLQWLIVLPLELVTASMTIQ-YWTDKVNP-----------AVWIAIFYVFIVIINLFGVkgygeaeFWFSSIKILA 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528006379 166 LLPLFILGILGIIFGDPING------------LANTSINTlNGTGWISALGPIAYSFDGWIVTTSISHELKDAKKNMPKA 233
Cdd:TIGR00913 155 IIGFIILSIILNCGGGPNHGyigfrywhdpgaFAGGTIGG-RFKGVCSVFVTAAFSFGGTELVALTAGEAANPRKSIPRA 233

                         250       260
                  ....*....|....*....|...
gi 2528006379 234 LMLGPLIVLSIYVLYFIGISCYV 256
Cdd:TIGR00913 234 AKRTFWRILVFYILTLFLIGFLV 256
2A0304 TIGR00907
amino acid permease (GABA permease); [Transport and binding proteins, Amino acids, peptides ...
 52-347 2.49e-03

amino acid permease (GABA permease); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273331 [Multi-domain]  Cd Length: 482  Bit Score: 40.11  E-value: 2.49e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528006379  52 FILAAISIIFGcLTIGELASRTDKVGGLISYAEMFLTRK---VACAM-GWFQTFVYYPTITSV---VAWVIGVYINI--- 121
Cdd:TIGR00907  54 IIAGAGSICIA-LSLAELSSAYPTSGGQYFWSAKLAPPRqmpFASWMtGWFNLAGQVAGTASTdlsVAQLILGIVSLttp 132

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528006379 122 --LFNLQASLEFEILIGYIFLLlcFVYNILLPKFGAFIQNSTTLIKLLPLFILGILGI------------IFGDPINgla 187
Cdd:TIGR00907 133 grEYIPTRWHIFGIMIGIHLIH--ALINSLPTKWLPRITSSAAYWSLLGFLTICITLLackspkfndgkfVFTNFNN--- 207

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528006379 188 NTSINTLNGTGWISALGPIAYSFDGWIVTTSISHELKDAKKNMPKALMLGPLIVLSIYVLYFIGIScYVTPEVVMTLGDR 267
Cdd:TIGR00907 208 STGGWKPGGFAFLLGLLNPAWSMTGYDGTAHMAEEIENPEVVGPRAIIGAVAIGIVTGFCFNIVLF-FSMGDIDSLISST 286

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528006379 268 HVSLAAQNLFGPAFSKMIIIFIVISVIGTVNGLVIGYI----RMPYSLSlRKNMFPFSKHLRKIDKRFQMPLNSAICSLI 343
Cdd:TIGR00907 287 TGQPIAQIFYNALGNKAGAIFLLCLILVTSFFCAITCMtansRMIYAFS-RDGGLPFSPLWSRVNPRTQVPLNAVWLSAV 365


                  ....
gi 2528006379 344 ICTI 347
Cdd:TIGR00907 366 WIIL 369
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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