|
Name |
Accession |
Description |
Interval |
E-value |
| pgi |
PRK00179 |
glucose-6-phosphate isomerase; Reviewed |
26-638 |
0e+00 |
|
glucose-6-phosphate isomerase; Reviewed
Pssm-ID: 234679 Cd Length: 548 Bit Score: 867.18 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 26 QPIDVATTREWNSLVDVFETVRGRHLRDLLA-ESGRRTAMTLEVGDLYLDFTRHRATPELLDALVVVAERAGLSERRDAM 104
Cdd:PRK00179 1 KNINLTQTPAWQALQAHADEIKDVHLRDLFAaDPDRFERFSLTAGGLLLDYSKNRITDETLALLLDLAREAGLEGARDAM 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 105 FAGEHINSTEDRAVGHVALRAPDDASFEIDGTDVVPEVHEVLEAMAELTDRVHSGEWVGATGEPIRTVINVGIGGSDLGP 184
Cdd:PRK00179 81 FAGEKINTTEDRAVLHTALRNPSNTPILVDGQDVMPEVHAVLARMKAFAEAVRSGEWKGYTGKAITDVVNIGIGGSDLGP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 185 EMAYRALRSYRQDGIECRFVSNVDPAGIAAATDGVDPATTLVVVVSKTFTTDETLTNAQTLKEWIRAGLAgptdaaatgd 264
Cdd:PRK00179 161 VMVTEALRPYADPGLRVHFVSNVDGAHLAETLKKLDPETTLFIVASKTFTTQETLTNAHSARDWFLAAGG---------- 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 265 adaagtiEESDgepaptqehgfaaelaskltddaddaddaddaddaddvdadadadadaddaeddddddddadadadddg 344
Cdd:PRK00179 231 -------DEAA--------------------------------------------------------------------- 234
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 345 ddeawVAKHFVAVSTNAEAVVEFGIDLDNMFRIWDWVGGRYSVWSAVGLSLMLAVGEDDFRALLDGAHTMDEHFRTAPLR 424
Cdd:PRK00179 235 -----VAKHFVAVSTNAEAVAEFGIDPDNMFGFWDWVGGRYSLWSAIGLSIALAIGPDNFEELLAGAHAMDEHFRTAPLE 309
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 425 DNAPVLVGLLRVLYRDLYGFPTHAVLPYAADLARFPAYLQQLDMESNGKRVRLDGSPATLRTGSVVWGQPGTNGQHAFYQ 504
Cdd:PRK00179 310 KNLPVLLALIGVWYRNFFGAQSHAVLPYDQYLHRFPAYLQQLEMESNGKSVDRDGTPVDYQTGPIIWGEPGTNGQHAFFQ 389
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 505 LLHQGTSIVPVDLIAFSESVDDEGDHQRKLLANVLAQGRALAEGRTAEEAEA--------AGVPADQVAHRTFPGNRPST 576
Cdd:PRK00179 390 LLHQGTKLVPADFIAPAQPHNPLGDHHDLLLANCFAQTEALMFGKTAEEVRAelrakgldEAEAEELAPHKVFPGNRPST 469
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2528069500 577 TILAPELTPAVLGQLIAMYEHSVFTQGVIWGINSFDQWGVELGKELASEILEQLESDEAQQA 638
Cdd:PRK00179 470 TILLDRLTPFTLGALIALYEHKVFVQGVIWGINSFDQWGVELGKQLAKRILPELEGDSEASA 531
|
|
| Pgi |
COG0166 |
Glucose-6-phosphate isomerase [Carbohydrate transport and metabolism]; Glucose-6-phosphate ... |
60-644 |
0e+00 |
|
Glucose-6-phosphate isomerase [Carbohydrate transport and metabolism]; Glucose-6-phosphate isomerase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 439936 Cd Length: 484 Bit Score: 659.14 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 60 RRTAMTLEVGDLYLDFTRHRATPELLDALVVVAERAglsERRDAMFAGEHINSTEDRAVGHVALRAPDDasfeidGTDVV 139
Cdd:COG0166 12 RFERFSLEAAGLLLDYSKNRITDETLELLLELAEEE---EAREALFAGEKINPTEGRAVLHGALRLPEA------GEDVM 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 140 PEVHEVLEAMAELTDRVHsgewvgaTGEPIRTVINVGIGGSDLGPEMAYRALRSYRQDGIECRFVSNVDPAGIAAATDGV 219
Cdd:COG0166 83 PEVREELARIKAFAEKVR-------TGKRITDVVNIGIGGSDLGPRAVIEALKPYFRDGPRVHFVSNVDPDYLAELLAGL 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 220 DPATTLVVVVSKTFTTDETLTNAQTLKEWIRaglagptdaaatgdadaagtieesdgepaptqEHGFAAelaskltddad 299
Cdd:COG0166 156 DPETTLFIVISKSGTTQETLTNARVAREWLE--------------------------------KAGGED----------- 192
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 300 daddaddaddaddvdadadadadaddaeddddddddadadadddgddeawVAKHFVAVSTNAEAVVEFGIDLD-NMFRIW 378
Cdd:COG0166 193 --------------------------------------------------AAKHFVAVTDNAGALRAFGIDEGyNTFPFP 222
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 379 DWVGGRYSVWSAVGLSLMLAVGEDdFRALLDGAHTMDEHFRTAPLRDNAPVLVGLLRVLYRDLYGFPTHAVLPYAADLAR 458
Cdd:COG0166 223 DWVGGRYSVLSAVGLLPAAAIGID-FEELLAGAHAMDEHFRTAPLEENPPVLLALLGIWYRNFKGAETEAVLPYDQRLER 301
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 459 FPAYLQQLDMESNGKRVRLDGSPATLRTGSVvwGQPGTNGQHAFYQLLHQGTSIVPVDLIAFSESVDDEGDhqrKLLANv 538
Cdd:COG0166 302 FPAWLQQLWMESNGKSVDRDGNPVGYGTGPV--GEPGTTDQHSFGQLLHQGTRDIPVTFIAVAEPHHDIPD---LLLAN- 375
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 539 lAQGRALAEGRTAEEAEAAGvpADQVAHRTFPGNRPSTTILAPELTPAVLGQLIAMYEHSVFTQGVIWGINSFDQWGVEL 618
Cdd:COG0166 376 -LQGLALLAGKTLDEVLALA--AEATPHALFPGNRPSNTILLPKLTPYTLGALIALYEHAVFVQGVLWGINPFDQPGVEL 452
|
570 580
....*....|....*....|....*.
gi 2528069500 619 GKELASEILEQLESDEAQQASGGAAR 644
Cdd:COG0166 453 GKKLAFALLGKLGGEEAAAGDSTEAL 478
|
|
| PGI |
pfam00342 |
Phosphoglucose isomerase; Phosphoglucose isomerase catalyzes the interconversion of ... |
74-634 |
0e+00 |
|
Phosphoglucose isomerase; Phosphoglucose isomerase catalyzes the interconversion of glucose-6-phosphate and fructose-6-phosphate.
Pssm-ID: 395271 Cd Length: 487 Bit Score: 634.90 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 74 DFTRHRATPELLDALVVVAERAGLSERRDAMFAGEHINSTEDRAVGHVALRAPDDASFEIDGTDVVPEVHEVLEAMAELT 153
Cdd:pfam00342 1 DYSKNHINDEILTALVKLAEERGVDAAREAMFNGEKINSTENRAVLHVALRNRSNTPIYVDGKDVMPEVNAVLAKMKSFS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 154 DRVHSGEWVGATGEPIRTVINVGIGGSDLGPEMAYRALRSYRQDGIECRFVSNVDPAGIAAATDGVDPATTLVVVVSKTF 233
Cdd:pfam00342 81 ERVRSGEWKGYTGKAITDVVNIGIGGSDLGPVMVTEALKPYSGRDLDVHFVSNVDGTHIAEVLKKLNPETTLFIVASKTF 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 234 TTDETLTNAQTLKEWIRAGLAGPTDaaatgdadaagtieesdgepaptqehgfaaelaskltddaddaddaddaddaddv 313
Cdd:pfam00342 161 TTAETMTNAESAKEWLLKALKDDSA------------------------------------------------------- 185
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 314 dadadadadaddaeddddddddadadadddgddeawVAKHFVAVSTNAEAVVEFGIDLDNMFRIWDWVGGRYSVWSAVGL 393
Cdd:pfam00342 186 ------------------------------------VAKHFIALSTNAEKVEEFGIDTKNMFEFWDWVGGRYSLWSAIGL 229
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 394 SLMLAVGEDDFRALLDGAHTMDEHFRTAPLRDNAPVLVGLLRVLYRDLYGFPTHAVLPYAADLARFPAYLQQLDMESNGK 473
Cdd:pfam00342 230 PIALSIGFENFQQLLEGAHAMDKHFLSAPPEKNIPVLLALLGVWYNNFFGAQTHAILPYDQYLHRFPAYLQQLDMESNGK 309
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 474 RVRLDGSPATLRTGSVVWGQPGTNGQHAFYQLLHQGTSIVPVDLIAFSESVDDE-GDHQRKLLANVLAQGRALAEGRTAE 552
Cdd:pfam00342 310 YVTRDGVLVDHQTGPIIFGEPGTNGQHAFYQLIHQGTRLIPCDFIGAVQSQNPEnGDHHKILLSNFFAQTEALMVGKSPE 389
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 553 EAE---AAGVPADQVAHRTFPGNRPSTTILAPELTPAVLGQLIAMYEHSVFTQGVIWGINSFDQWGVELGKELASEILEQ 629
Cdd:pfam00342 390 EVRkelAAADVEHLIPHKTFTGNRPSNSILVQKLTPATLGALIAMYEHKIFVQGAIWGINSFDQWGVELGKVLAKSILPE 469
|
....*
gi 2528069500 630 LESDE 634
Cdd:pfam00342 470 LENSN 474
|
|
| SIS_PGI_2 |
cd05016 |
Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification ... |
445-626 |
3.99e-78 |
|
Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of glucose 6-phosphate to fructose 6-phosphate. As an extracellular protein, PGI also has functions equivalent to neuroleukin (NLK), autocrine motility factor (AMF), and maturation factor (MF). Evidence suggests that PGI, NLK, AMF, and MF are closely related or identical. NLK is a neurotrophic growth factor that promotes regeneration and survival of neurons. The dimeric form of NLK has isomerase function, whereas its monomeric form carries out neurotrophic activity. AMF is a cytokine that stimulates cell migration and metastasis. MF mediates the differentiation of human myeloid leukemic HL-60 cells to terminal monocytic cells.
Pssm-ID: 240147 Cd Length: 164 Bit Score: 245.59 E-value: 3.99e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 445 PTHAVLPYAADLARFPAYLQQLDMESNGKRVRLDGSPAtlRTGSVVWGQPGTNGQHAFYQLLHQGTSIVPVDLIAFSESV 524
Cdd:cd05016 1 KTHALLPYSQRLERFPAWLQQLDMESNGKSVTRDGEDY--PTGPIPWGAPGTNDQHSFFQLIHQGTKDKPVDFIAVKKPQ 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 525 DD------EGDHQRKLLANVLAQGRALAegrtaeeaeaagvpadqvahrtFPGNRPSTTILAPELTPAVLGQLIAMYEHS 598
Cdd:cd05016 79 NDvldylaGKTLHDLLLANCLATREALM----------------------FPGGRPSNTIVLPELTPYTLGALLALYEHK 136
|
170 180
....*....|....*....|....*...
gi 2528069500 599 VFTQGVIWGINSFDQWGVELGKELASEI 626
Cdd:cd05016 137 TAVQGALLGINPFDQPGVELGKKLAKKI 164
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| pgi |
PRK00179 |
glucose-6-phosphate isomerase; Reviewed |
26-638 |
0e+00 |
|
glucose-6-phosphate isomerase; Reviewed
Pssm-ID: 234679 Cd Length: 548 Bit Score: 867.18 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 26 QPIDVATTREWNSLVDVFETVRGRHLRDLLA-ESGRRTAMTLEVGDLYLDFTRHRATPELLDALVVVAERAGLSERRDAM 104
Cdd:PRK00179 1 KNINLTQTPAWQALQAHADEIKDVHLRDLFAaDPDRFERFSLTAGGLLLDYSKNRITDETLALLLDLAREAGLEGARDAM 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 105 FAGEHINSTEDRAVGHVALRAPDDASFEIDGTDVVPEVHEVLEAMAELTDRVHSGEWVGATGEPIRTVINVGIGGSDLGP 184
Cdd:PRK00179 81 FAGEKINTTEDRAVLHTALRNPSNTPILVDGQDVMPEVHAVLARMKAFAEAVRSGEWKGYTGKAITDVVNIGIGGSDLGP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 185 EMAYRALRSYRQDGIECRFVSNVDPAGIAAATDGVDPATTLVVVVSKTFTTDETLTNAQTLKEWIRAGLAgptdaaatgd 264
Cdd:PRK00179 161 VMVTEALRPYADPGLRVHFVSNVDGAHLAETLKKLDPETTLFIVASKTFTTQETLTNAHSARDWFLAAGG---------- 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 265 adaagtiEESDgepaptqehgfaaelaskltddaddaddaddaddaddvdadadadadaddaeddddddddadadadddg 344
Cdd:PRK00179 231 -------DEAA--------------------------------------------------------------------- 234
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 345 ddeawVAKHFVAVSTNAEAVVEFGIDLDNMFRIWDWVGGRYSVWSAVGLSLMLAVGEDDFRALLDGAHTMDEHFRTAPLR 424
Cdd:PRK00179 235 -----VAKHFVAVSTNAEAVAEFGIDPDNMFGFWDWVGGRYSLWSAIGLSIALAIGPDNFEELLAGAHAMDEHFRTAPLE 309
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 425 DNAPVLVGLLRVLYRDLYGFPTHAVLPYAADLARFPAYLQQLDMESNGKRVRLDGSPATLRTGSVVWGQPGTNGQHAFYQ 504
Cdd:PRK00179 310 KNLPVLLALIGVWYRNFFGAQSHAVLPYDQYLHRFPAYLQQLEMESNGKSVDRDGTPVDYQTGPIIWGEPGTNGQHAFFQ 389
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 505 LLHQGTSIVPVDLIAFSESVDDEGDHQRKLLANVLAQGRALAEGRTAEEAEA--------AGVPADQVAHRTFPGNRPST 576
Cdd:PRK00179 390 LLHQGTKLVPADFIAPAQPHNPLGDHHDLLLANCFAQTEALMFGKTAEEVRAelrakgldEAEAEELAPHKVFPGNRPST 469
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2528069500 577 TILAPELTPAVLGQLIAMYEHSVFTQGVIWGINSFDQWGVELGKELASEILEQLESDEAQQA 638
Cdd:PRK00179 470 TILLDRLTPFTLGALIALYEHKVFVQGVIWGINSFDQWGVELGKQLAKRILPELEGDSEASA 531
|
|
| Pgi |
COG0166 |
Glucose-6-phosphate isomerase [Carbohydrate transport and metabolism]; Glucose-6-phosphate ... |
60-644 |
0e+00 |
|
Glucose-6-phosphate isomerase [Carbohydrate transport and metabolism]; Glucose-6-phosphate isomerase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 439936 Cd Length: 484 Bit Score: 659.14 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 60 RRTAMTLEVGDLYLDFTRHRATPELLDALVVVAERAglsERRDAMFAGEHINSTEDRAVGHVALRAPDDasfeidGTDVV 139
Cdd:COG0166 12 RFERFSLEAAGLLLDYSKNRITDETLELLLELAEEE---EAREALFAGEKINPTEGRAVLHGALRLPEA------GEDVM 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 140 PEVHEVLEAMAELTDRVHsgewvgaTGEPIRTVINVGIGGSDLGPEMAYRALRSYRQDGIECRFVSNVDPAGIAAATDGV 219
Cdd:COG0166 83 PEVREELARIKAFAEKVR-------TGKRITDVVNIGIGGSDLGPRAVIEALKPYFRDGPRVHFVSNVDPDYLAELLAGL 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 220 DPATTLVVVVSKTFTTDETLTNAQTLKEWIRaglagptdaaatgdadaagtieesdgepaptqEHGFAAelaskltddad 299
Cdd:COG0166 156 DPETTLFIVISKSGTTQETLTNARVAREWLE--------------------------------KAGGED----------- 192
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 300 daddaddaddaddvdadadadadaddaeddddddddadadadddgddeawVAKHFVAVSTNAEAVVEFGIDLD-NMFRIW 378
Cdd:COG0166 193 --------------------------------------------------AAKHFVAVTDNAGALRAFGIDEGyNTFPFP 222
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 379 DWVGGRYSVWSAVGLSLMLAVGEDdFRALLDGAHTMDEHFRTAPLRDNAPVLVGLLRVLYRDLYGFPTHAVLPYAADLAR 458
Cdd:COG0166 223 DWVGGRYSVLSAVGLLPAAAIGID-FEELLAGAHAMDEHFRTAPLEENPPVLLALLGIWYRNFKGAETEAVLPYDQRLER 301
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 459 FPAYLQQLDMESNGKRVRLDGSPATLRTGSVvwGQPGTNGQHAFYQLLHQGTSIVPVDLIAFSESVDDEGDhqrKLLANv 538
Cdd:COG0166 302 FPAWLQQLWMESNGKSVDRDGNPVGYGTGPV--GEPGTTDQHSFGQLLHQGTRDIPVTFIAVAEPHHDIPD---LLLAN- 375
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 539 lAQGRALAEGRTAEEAEAAGvpADQVAHRTFPGNRPSTTILAPELTPAVLGQLIAMYEHSVFTQGVIWGINSFDQWGVEL 618
Cdd:COG0166 376 -LQGLALLAGKTLDEVLALA--AEATPHALFPGNRPSNTILLPKLTPYTLGALIALYEHAVFVQGVLWGINPFDQPGVEL 452
|
570 580
....*....|....*....|....*.
gi 2528069500 619 GKELASEILEQLESDEAQQASGGAAR 644
Cdd:COG0166 453 GKKLAFALLGKLGGEEAAAGDSTEAL 478
|
|
| PLN02649 |
PLN02649 |
glucose-6-phosphate isomerase |
27-639 |
0e+00 |
|
glucose-6-phosphate isomerase
Pssm-ID: 215351 [Multi-domain] Cd Length: 560 Bit Score: 635.54 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 27 PIDVATTREWNSLVDVFETVRGRHLRDLLAESGRRTAMTLEVGDLYLDFTRHRATPELLDALVVVAERAGLSERRDAMFA 106
Cdd:PLN02649 5 TLLISDTPAWKRLVAHVYQIKKTHLRELLNDAERCQSMIAEFDGIYLDYSRQRVTDETMELLFPLAEAANLFEKIEAMFS 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 107 GEHINSTEDRAVGHVALRAPDDASFEIDGTDVVPEVHEVLEAMAELTDRVHSGEWVGATGEPIRTVINVGIGGSDLGPEM 186
Cdd:PLN02649 85 GEIINSTEDRAVLHVALRAPRLAPILVDGKNVVPEVWEVLDKIKAFSEDVRSGKWKGATGKRFTNVVSIGIGGSFLGPLF 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 187 AYRALRSY-----RQDGIECRFVSNVDPAGIAAATDGVDPATTLVVVVSKTFTTDETLTNAQTLKEWIRAGLAGPTdaaa 261
Cdd:PLN02649 165 VHEALATDpealkSAKGRKLRFLANVDPVDIARQIAQLDPETTLVVVVSKTFTTAETMLNARTVRKWLRDALGGLA---- 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 262 tgdadaagtieesdgepaptqehgfaaelaskltddaddaddaddaddaddvdadadadadaddaeddddddddadadad 341
Cdd:PLN02649 --------------------------------------------------------------------------------
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 342 ddgddeawVAKHFVAVSTNAEAVVEFGIDLDNMFRIWDWVGGRYSVWSAVG-LSLMLAVGEDDFRALLDGAHTMDEHFRT 420
Cdd:PLN02649 241 --------VAKHMVAVSTNLLLVNKFGIDPWNAFPFWDWVGGRYSVCSAVGlLPLSLQYGFDVVEEFLEGAASMDEHFRT 312
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 421 APLRDNAPVLVGLLRVLYRDLYGFPTHAVLPYAADLARFPAYLQQLDMESNGKRVRLDGSPATLRTGSVVWGQPGTNGQH 500
Cdd:PLN02649 313 APLKENIPVLLGLLSVWNSSFLGYPARAILPYSQALLKFAPHIQQLDMESNGKGVDLDGNPLPVNTGEIDFGEPGTNGQH 392
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 501 AFYQLLHQGtSIVPVDLIAFSES----VDDEG---DHQRKLLANVLAQGRALAEGRTAEEAEAAGVPADQVAHRTFPGNR 573
Cdd:PLN02649 393 SFYQLIHQG-RNIPCDFIGVVRSqqpvHLWLGegvSNHDELMSNFFAQPDALAYGKTPEQLRAEGVPEELIPHKVFAGNR 471
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2528069500 574 PSTTILAPELTPAVLGQLIAMYEHSVFTQGVIWGINSFDQWGVELGKELASEILEQLESDEAQQAS 639
Cdd:PLN02649 472 PSLSILLPELTAYTVGQLLALYEHRVAVQGFIWNINSFDQWGVELGKALAKRVRAVLNEARTKGEP 537
|
|
| PGI |
pfam00342 |
Phosphoglucose isomerase; Phosphoglucose isomerase catalyzes the interconversion of ... |
74-634 |
0e+00 |
|
Phosphoglucose isomerase; Phosphoglucose isomerase catalyzes the interconversion of glucose-6-phosphate and fructose-6-phosphate.
Pssm-ID: 395271 Cd Length: 487 Bit Score: 634.90 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 74 DFTRHRATPELLDALVVVAERAGLSERRDAMFAGEHINSTEDRAVGHVALRAPDDASFEIDGTDVVPEVHEVLEAMAELT 153
Cdd:pfam00342 1 DYSKNHINDEILTALVKLAEERGVDAAREAMFNGEKINSTENRAVLHVALRNRSNTPIYVDGKDVMPEVNAVLAKMKSFS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 154 DRVHSGEWVGATGEPIRTVINVGIGGSDLGPEMAYRALRSYRQDGIECRFVSNVDPAGIAAATDGVDPATTLVVVVSKTF 233
Cdd:pfam00342 81 ERVRSGEWKGYTGKAITDVVNIGIGGSDLGPVMVTEALKPYSGRDLDVHFVSNVDGTHIAEVLKKLNPETTLFIVASKTF 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 234 TTDETLTNAQTLKEWIRAGLAGPTDaaatgdadaagtieesdgepaptqehgfaaelaskltddaddaddaddaddaddv 313
Cdd:pfam00342 161 TTAETMTNAESAKEWLLKALKDDSA------------------------------------------------------- 185
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 314 dadadadadaddaeddddddddadadadddgddeawVAKHFVAVSTNAEAVVEFGIDLDNMFRIWDWVGGRYSVWSAVGL 393
Cdd:pfam00342 186 ------------------------------------VAKHFIALSTNAEKVEEFGIDTKNMFEFWDWVGGRYSLWSAIGL 229
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 394 SLMLAVGEDDFRALLDGAHTMDEHFRTAPLRDNAPVLVGLLRVLYRDLYGFPTHAVLPYAADLARFPAYLQQLDMESNGK 473
Cdd:pfam00342 230 PIALSIGFENFQQLLEGAHAMDKHFLSAPPEKNIPVLLALLGVWYNNFFGAQTHAILPYDQYLHRFPAYLQQLDMESNGK 309
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 474 RVRLDGSPATLRTGSVVWGQPGTNGQHAFYQLLHQGTSIVPVDLIAFSESVDDE-GDHQRKLLANVLAQGRALAEGRTAE 552
Cdd:pfam00342 310 YVTRDGVLVDHQTGPIIFGEPGTNGQHAFYQLIHQGTRLIPCDFIGAVQSQNPEnGDHHKILLSNFFAQTEALMVGKSPE 389
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 553 EAE---AAGVPADQVAHRTFPGNRPSTTILAPELTPAVLGQLIAMYEHSVFTQGVIWGINSFDQWGVELGKELASEILEQ 629
Cdd:pfam00342 390 EVRkelAAADVEHLIPHKTFTGNRPSNSILVQKLTPATLGALIAMYEHKIFVQGAIWGINSFDQWGVELGKVLAKSILPE 469
|
....*
gi 2528069500 630 LESDE 634
Cdd:pfam00342 470 LENSN 474
|
|
| PTZ00430 |
PTZ00430 |
glucose-6-phosphate isomerase; Provisional |
29-626 |
0e+00 |
|
glucose-6-phosphate isomerase; Provisional
Pssm-ID: 185612 Cd Length: 552 Bit Score: 565.41 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 29 DVATTREWNSLVDVFETVRGRHLRDLLAESGRRTAMTLEVGDLYLDFTRHRATPELLDALVVVAERAGLSERRDAMFAGE 108
Cdd:PTZ00430 2 DLESLKSYKNLLSLAEKLKKVHLRDLLKDEERNKSLIKEFKGVTLDLSRQRLDEETLKLLIELAEEAKLKEKIKDMFNGE 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 109 HINSTEDRAVGHVALRAPDDASFEIDGTDVVPEVHEVLEAMAELTDRVHSGEWVGATGEPIRTVINVGIGGSDLGPEMAY 188
Cdd:PTZ00430 82 KINTTENRAVLHTALRAPRGEKVVVDGKNVLEDVHEVLDRIKKFSDKIRSGEILGSTGKKLKNVICIGIGGSYLGTEFVY 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 189 RALRSY-----RQDGIECRFVSNVDPAGIAAATDGVDPATTLVVVVSKTFTTDETLTNAQTLKEWIRAGLAGPTDaaatg 263
Cdd:PTZ00430 162 EALRTYgeareASKGRKLRFLANVDPIDVRRATEGLDPEETLVVIISKTFTTAETMLNAKTVRQWLLDNIKSKEA----- 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 264 dadaagtieesdgepaptqehgfaaelaskltddaddaddaddaddaddvdadadadadaddaeddddddddadadaddd 343
Cdd:PTZ00430 --------------------------------------------------------------------------------
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 344 gddeawVAKHFVAVSTNAEAVVEFGIDLDNMFRIWDWVGGRYSVWSAVG-LSLMLAVGEDDFRALLDGAHTMDEHFRTAP 422
Cdd:PTZ00430 237 ------LSKHLCAVSTNLKLTSEFGIPDENVFGFWDWVGGRFSVTSAVGiLPLSIQFGYDIVQQFLNGCHDMDEHFRTAP 310
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 423 LRDNAPVLVGLLRVLYRDLYGFPTHAVLPYAADLARFPAYLQQLDMESNGKRVRLDGSPATLRTGSVVWGQPGTNGQHAF 502
Cdd:PTZ00430 311 LEENLPVLLGLTSFYNSTFLGYNCVAILPYCQALLKFPAHVQQLLMESNGKSVTLDGNTLDYNTGEIYFGEPGTNGQHSF 390
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 503 YQLLHQGTsIVPVDLIAFSESVDDEG------DHQRKLLANVLAQGRALAEGRTAEEAEAAGVPADQVAHRTFPGNRPST 576
Cdd:PTZ00430 391 YQLLHQGR-VVPSEFIGFAKSQNPIKllgepvSNHDELMSNFFAQPDALAFGKTYEELEKEGVPEELIPHKVFPGNRPSL 469
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|
gi 2528069500 577 TILAPELTPAVLGQLIAMYEHSVFTQGVIWGINSFDQWGVELGKELASEI 626
Cdd:PTZ00430 470 LLLFPELNPYTIGQLLALYEHRTVVEGFLWNINSFDQWGVELGKVLAKDV 519
|
|
| pgi |
PRK14095 |
glucose-6-phosphate isomerase; Provisional |
66-635 |
2.66e-138 |
|
glucose-6-phosphate isomerase; Provisional
Pssm-ID: 237608 Cd Length: 533 Bit Score: 414.80 E-value: 2.66e-138
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 66 LEVGDLYLDFTRHRATPELLDALVVVAERAGLSERRDAMFAGEHINS-----TEDRAVGHVALRAP-DDASFEIDGTDVV 139
Cdd:PRK14095 42 LSGEGFTYNYATERVDDRILAALQNLADEAELIEKMKAMQNGAVINRiegfpSENRPVLHTATRGQvGDSVLTDEAEDMA 121
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 140 PEVHEVLEAMAELTDRVHSGEWVGATGEPIRTVINVGIGGSDLGPEMAYRALRSYRQDGIECRFVSNVDPAGIAAATDGV 219
Cdd:PRK14095 122 EFSKRELERLAEFLKKVRSGEIKNSNGKKFTTVVQIGIGGSDLGPKALYLALKNYAKKDKRVHFISNVDPDDAAEVLSEI 201
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 220 DPATTLVVVVSKTFTTDETLTNAQTLKEWIR-AGLAgptdaaatgdadaagtieesdgepaptqehgfaaelaskltdda 298
Cdd:PRK14095 202 DLAKTLFIVVSKSGTTLETAANEEFVRDALKkAGLD-------------------------------------------- 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 299 ddaddaddaddaddvdadadadadaddaeddddddddadadadddgddeawVAKHFVAVSTNaeavvefGIDLDN----- 373
Cdd:PRK14095 238 ---------------------------------------------------YKKHFIAVTSE-------GSPMDDesgyl 259
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 374 -MFRIWDWVGGRYSVWSAVGLSLM-LAVGEDDFRALLDGAHTMDEHFRTAPLRDNAPVLVGLLRVLYRDLYGFPTHAVLP 451
Cdd:PRK14095 260 eVFHMWDSIGGRFSSTSMVGGVVLgFAFGFEVFKEFLKGAAAMDKAALNPNIRENLPLLAALIGIWNRNFLGYPTTAVIP 339
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 452 YAADLARFPAYLQQLDMESNGKRVRLDGSPATLRTGSVVWGQPGTNGQHAFYQLLHQGTSIVPVDLIAFSES------VD 525
Cdd:PRK14095 340 YSQALERFPAHLQQLDMESNGKSVNRFGEPINFKTGPIIWGEPGTNGQHSFFQLLHQGTDIVPVEFIGFKESqlgqdiVI 419
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 526 DEGDHQRKLLANVLAQGRALAEGRTaeeaeaagvpaDQVAHRTFPGNRPSTTILAPELTPAVLGQLIAMYEHSVFTQGVI 605
Cdd:PRK14095 420 QGSTSQQKLFANLIAQIIALACGKE-----------NTNPNKNFKGNRPSSLLVAKQLTPYTLGALLAHYENKVMFQGFC 488
|
570 580 590
....*....|....*....|....*....|
gi 2528069500 606 WGINSFDQWGVELGKELASEILEQLESDEA 635
Cdd:PRK14095 489 WNINSFDQEGVQLGKVLANQILGIMKGEAP 518
|
|
| SIS_PGI_2 |
cd05016 |
Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification ... |
445-626 |
3.99e-78 |
|
Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of glucose 6-phosphate to fructose 6-phosphate. As an extracellular protein, PGI also has functions equivalent to neuroleukin (NLK), autocrine motility factor (AMF), and maturation factor (MF). Evidence suggests that PGI, NLK, AMF, and MF are closely related or identical. NLK is a neurotrophic growth factor that promotes regeneration and survival of neurons. The dimeric form of NLK has isomerase function, whereas its monomeric form carries out neurotrophic activity. AMF is a cytokine that stimulates cell migration and metastasis. MF mediates the differentiation of human myeloid leukemic HL-60 cells to terminal monocytic cells.
Pssm-ID: 240147 Cd Length: 164 Bit Score: 245.59 E-value: 3.99e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 445 PTHAVLPYAADLARFPAYLQQLDMESNGKRVRLDGSPAtlRTGSVVWGQPGTNGQHAFYQLLHQGTSIVPVDLIAFSESV 524
Cdd:cd05016 1 KTHALLPYSQRLERFPAWLQQLDMESNGKSVTRDGEDY--PTGPIPWGAPGTNDQHSFFQLIHQGTKDKPVDFIAVKKPQ 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 525 DD------EGDHQRKLLANVLAQGRALAegrtaeeaeaagvpadqvahrtFPGNRPSTTILAPELTPAVLGQLIAMYEHS 598
Cdd:cd05016 79 NDvldylaGKTLHDLLLANCLATREALM----------------------FPGGRPSNTIVLPELTPYTLGALLALYEHK 136
|
170 180
....*....|....*....|....*...
gi 2528069500 599 VFTQGVIWGINSFDQWGVELGKELASEI 626
Cdd:cd05016 137 TAVQGALLGINPFDQPGVELGKKLAKKI 164
|
|
| SIS_PGI_1 |
cd05015 |
Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification ... |
143-398 |
5.36e-55 |
|
Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of glucose 6-phosphate to fructose 6-phosphate. As an extracellular protein, PGI also has functions equivalent to neuroleukin (NLK), autocrine motility factor (AMF), and maturation factor (MF). Evidence suggests that PGI, NLK, AMF, and MF are closely related or identical. NLK is a neurotrophic growth factor that promotes regeneration and survival of neurons. The dimeric form of NLK has isomerase function, whereas its monomeric form carries out neurotrophic activity. AMF is a cytokine that stimulates cell migration and metastasis. MF mediates the differentiation of human myeloid leukemic HL-60 cells to terminal monocytic cells.
Pssm-ID: 240146 Cd Length: 158 Bit Score: 184.27 E-value: 5.36e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 143 HEVLEAMAELTDRVHSGEwvgatgePIRTVINVGIGGSDLGPEMAYRALRSYRQDGIECRFVSNVDPAGIAAATDGVDPA 222
Cdd:cd05015 1 RAELERIKEFAEKVRSGK-------KITDVVVIGIGGSDLGPRAVYEALKPYFKGGLRLHFVSNVDPDDLAELLKKLDPE 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 223 TTLVVVVSKTFTTDETLTNAQTLKEWIRAGLagptdaaatgdadaagtieesdgepaptqehgfaaelaskltddaddad 302
Cdd:cd05015 74 TTLFIVISKSGTTLETLANARLAREWLEEAG------------------------------------------------- 104
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 303 daddaddaddvdadadadadaddaeddddddddadadadddgddEAWVAKHFVAVSTNAEAVVE-FGIDLDNMFRIWDWV 381
Cdd:cd05015 105 --------------------------------------------GDDLAKHFVAITDNGSGLLKkAGIEGLNTFEIPDWV 140
|
250
....*....|....*...
gi 2528069500 382 GGRYSV-WSAVGLSLMLA 398
Cdd:cd05015 141 GGRFSVlSSVGGLPLALA 158
|
|
| pgi |
PRK14096 |
glucose-6-phosphate isomerase; Provisional |
70-642 |
4.84e-50 |
|
glucose-6-phosphate isomerase; Provisional
Pssm-ID: 237609 [Multi-domain] Cd Length: 528 Bit Score: 182.39 E-value: 4.84e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 70 DLYLDFTRHRATPELLDALVVVAERAglSERRDAMFAGEHINSTEDRAVGHVALRAPDDASFEidgtDVVPEVHEVLEAM 149
Cdd:PRK14096 21 GLWLDISRMNFDDAFLESLEPKFQKA--FAAMAALEAGAIANPDEGRMVGHYWLRNPELAPTP----EIRAEITETLAQI 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 150 AELTDRVHSGEWVGATGEPIRTVINVGIGGSDLGPEMAYRALRSyRQDGIECRFVSNVDPAGIAAATDGVDP--ATTLVV 227
Cdd:PRK14096 95 EAFAAKVHSGTIKPPNGEKFTDVLWIGIGGSALGPQFVAEALQP-NSDGLNIHFIDNTDPDGIDRVLAELGDrlATTLVV 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 228 VVSKTFTTDETLtNA--QTLKEWIRAGLagptdaaatgdadaagtieesdgepaptqehgfaaelaskltddaddaddad 305
Cdd:PRK14096 174 VISKSGGTPETR-NGmlEAKAAYEAAGL---------------------------------------------------- 200
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 306 daddaddvdadadadadaddaeddddddddadadadddgddeAWvAKHFVAVSTNaeavvefGIDLDN---------MFR 376
Cdd:PRK14096 201 ------------------------------------------DF-ASHAVAITMK-------GSKLDQlaqsegwlaRFP 230
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 377 IWDWVGGRYSVWSAVGLsLMLAVGEDDFRALLDGAHTMDEHFRTAPLRDNAPVLVGLLRVLYRDLYGFPTHAVLPYAADL 456
Cdd:PRK14096 231 MWDWVGGRTSETSAVGL-LPAALQGIDIRAFLAGAKQMDEATRVPDLKNNPAALLALAWYYAGDGKGKKDMVVLPYKDRL 309
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 457 ARFPAYLQQLDMESNGKRVRLDGSpaTLRTGSVVWGQPGTNGQHAFYQLLHQGtsiVPVDLIAFSESVDDEGDHQRKLLA 536
Cdd:PRK14096 310 LLFSRYLQQLVMESLGKELDLDGN--VVHQGIAVYGNKGSTDQHAYVQQLRDG---VDNFFVTFIEVLEDRQGSSIEVEP 384
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 537 NVLA--------QG--RALAEgrtaeeaeaagvpadqvahrtfpGNRPSTTILAPELTPAVLGQLIAMYEHSVFTQGVIW 606
Cdd:PRK14096 385 GVTSgdylsgflQGtrQALYE-----------------------NGRQSITITIPEVNPRTLGALIALFERAVGLYASLV 441
|
570 580 590
....*....|....*....|....*....|....*..
gi 2528069500 607 GINSFDQWGVELGKELASEILE-QLESDEAQQASGGA 642
Cdd:PRK14096 442 NINAYHQPGVEAGKKAAAAILDlQKKVEELLKEDGGE 478
|
|
| PRK00973 |
PRK00973 |
glucose-6-phosphate isomerase; Provisional |
171-629 |
1.28e-28 |
|
glucose-6-phosphate isomerase; Provisional
Pssm-ID: 179193 [Multi-domain] Cd Length: 446 Bit Score: 119.33 E-value: 1.28e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 171 TVINVGIGGSDLGPEMAYRALR--SYRQDGIECR------FVSNVDPAGIAAATDGVDPATTLVVVVSKTFTTDETLTNA 242
Cdd:PRK00973 73 NVVVLGIGGSALGNLALHYALNplNWNELSKEERngprvfVLDNVDPEKTASILDVIDLEKTLFNVISKSGNTAETLANY 152
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 243 QTLKEWIraglagptdaaatgdadaagtieesdgepaptQEHGFAaelaskltddaddaddaddaddaddvdadadadad 322
Cdd:PRK00973 153 LIIRGIL--------------------------------EKLGLD----------------------------------- 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 323 addaeddddddddadadadddgddeawVAKHFVAVsTNAEAVV------EFGIDldnMFRIWDWVGGRYSVWSAVGLSLM 396
Cdd:PRK00973 166 ---------------------------PKKHLVFT-TDPEKGKlkkiaeKEGYR---TLEIPENVGGRFSVLTPVGLAPA 214
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 397 LAVGEDdFRALLDGAHTMDEHFRTAPLRDNAPVLVGLLRVLYrDLYGFPTHAVLPYAADLARFPAYLQQLDMESNGKRvr 476
Cdd:PRK00973 215 AALGID-IEELLEGAKEMDKICEKEDIFKNPALLNALIHYLY-YNRGKNISVMMPYSERLKYFGDWYRQLWAESLGKK-- 290
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 477 ldgspatlRTGSVVWGQPGTNGQHAFYQLLHQGtsivPVDLIA-------FSESVDDEGDHQRKLLANVLaQGRALAEGR 549
Cdd:PRK00973 291 --------GVGQTPVKALGATDQHSQLQLYMEG----PKDKIItflkvekYRRDVEIPYEYEDIEELSYL-GGHKLSELI 357
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 550 TAEEA--EAAgvpadqVAHRtfpgNRPSTTILAPELTPAVLGQLIAMYEHSVFTQGVIWGINSFDQWGVELGKELASEIL 627
Cdd:PRK00973 358 NSEQKgtEIA------LTEN----GRPNVKITLDELNEYTVGQLFYMYEMQTAFMGELLNINAFDQPGVELGKKITYALL 427
|
..
gi 2528069500 628 EQ 629
Cdd:PRK00973 428 GR 429
|
|
| PRK03868 |
PRK03868 |
glucose-6-phosphate isomerase; Provisional |
169-629 |
5.80e-16 |
|
glucose-6-phosphate isomerase; Provisional
Pssm-ID: 235168 Cd Length: 410 Bit Score: 80.36 E-value: 5.80e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 169 IRTVINVGIGGSDLGPEMAYRALRSYRQDGIECRFVSNVDPAGIAAATDGVDPATTLVVVVSKTFTTDETLTnaqTLKEW 248
Cdd:PRK03868 58 IKNIVVIGIGGSSLGVKAIYSFLKNEKNNKKELHFLENTDPISINKTLSKINLENTLFIVISKSGTTIETIS---IFKYL 134
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 249 IraglagptdaaatgdadaagtieesdgepaptqEHgFAAELASKltddaddaddaddaddaddvdadadadadaddaed 328
Cdd:PRK03868 135 L---------------------------------SH-FKLDQELK----------------------------------- 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 329 dddddddadadadddgddeawvaKHFVAVSTNAEAVVEFGIDLD-NMFRIWDWVGGRYSVWSAVGLsLMLAVGEDDFRAL 407
Cdd:PRK03868 146 -----------------------KNFLFITDPDSKLEQFAKENNiKCFNIPKNVGGRFSVLSAVGI-VPLALCGYDIKAL 201
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 408 LDGAHTMDEHFrtapLRDNAPVLVGLLRVLYRDLYGFPTHAVLPYAADLARFPAYLQQLDMESNGKRVRLDGspatlRTG 487
Cdd:PRK03868 202 LEGAKACKDSF----FEQKEDHILKKAYFYATHKNAYNINVLFSYSDALKGFNDWYVQLWGESLGKKQGYKT-----RVG 272
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 488 SVVWGQPGTNGQHAFYQLLHQGT-----------------SIVPVDLiAFSESVDDEGDHQRKLLANvlAQGRAlaegrT 550
Cdd:PRK03868 273 LTPIGLIGSRDQHSFLQLIMEGPrdktvtfikikdfqnapKIPNISL-KGLESLDFVNGVSFNELIN--AQCDA-----T 344
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 551 AEEAEAAGVPADqvahrtfpgnrpstTILAPELTPAVLGQLIAMYEhsVFTQ--GVIWGINSFDQWGVELGKELASEILE 628
Cdd:PRK03868 345 MEALIAEDIPVD--------------VITLEKLDEFSIGYLIYYYE--LLTSavGKMLGINTYDQPGVEVGKRILKEKLQ 408
|
.
gi 2528069500 629 Q 629
Cdd:PRK03868 409 S 409
|
|
| pgi |
PRK14097 |
glucose-6-phosphate isomerase; Provisional |
374-630 |
3.11e-10 |
|
glucose-6-phosphate isomerase; Provisional
Pssm-ID: 184504 Cd Length: 448 Bit Score: 62.93 E-value: 3.11e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 374 MFRIWDWVGGRYSVWSAVGLsLMLAVGEDDFRALLDGAHTMDEHFRTAPLRDNAPVLVGLLR-VLYRDlyGFPTHAVLPY 452
Cdd:PRK14097 197 TFVIPDDVGGRFSVLTAVGL-LPIAVAGIDIDALMKGAADARKDYSSSDLSENPAYQYAAVRnILYRK--GYTTEILVNY 273
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 453 AADLARFPAYLQQLDMESNGKrvrlDGS---PAtlrtgSVVWgqpgTNGQHAFYQLLHQGTSIV---------PVDLIAF 520
Cdd:PRK14097 274 EPSLQYFSEWWKQLFGESEGK----DQKgifPA-----SANF----STDLHSLGQYIQEGRRNLfetvikvekPRKDLTI 340
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 521 SESVDDEgDhqrKLlaNVLAqGRALAE-GRTAEEAEaagvpadQVAHRTfpGNRPSTTILAPELTPAVLGQLIAMYEHSV 599
Cdd:PRK14097 341 PEDEEDL-D---GL--NYLA-GKTVDFvNKKAFEGT-------LLAHTD--GGVPNIVVNIPELDEYTFGYLVYFFEKAC 404
|
250 260 270 280
....*....|....*....|....*....|....*....|....
gi 2528069500 600 FTQGVIWGINSFDQWGVE---------LGK----ELASEILEQL 630
Cdd:PRK14097 405 AISGYLLGVNPFDQPGVEaykknmfalLGKpgfeELKAELEARL 448
|
|
| PRK09533 |
PRK09533 |
bifunctional transaldolase/phosoglucose isomerase; Validated |
353-633 |
1.81e-05 |
|
bifunctional transaldolase/phosoglucose isomerase; Validated
Pssm-ID: 236551 [Multi-domain] Cd Length: 948 Bit Score: 48.04 E-value: 1.81e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 353 HFVAVS---TNAEAVVEfgidLDNMFRIWDWV---GGRYSVWSAVGLSLMLAVGEdDFRALLDGAHTMDEHFRT-APLRD 425
Cdd:PRK09533 545 HFVAVTdpgSSLEKVAK----EDGFRKIFHGDpdiGGRYSVLSPFGLVPAAAAGI-DVRALLDSALAMVRSCGPsVPPAD 619
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 426 NAPVLVGL----LRVLYRDLYGFPThavlpyAADLARFPAYLQQLDMESNGKrvrldgspatlrtgsvvwgqpgtngqha 501
Cdd:PRK09533 620 NPGVQLGLalgvAATQGRDKVTIVA------SPAIADFGAWAEQLIAESTGK---------------------------- 665
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 502 fyqllhQGTSIVPVDliafSESVDDEGD--HQRkllanVLAQGRALAEGRTAEEA-----EAAGVPadqVAHRTFPgnrp 574
Cdd:PRK09533 666 ------EGKGLIPID----GEPLGDPAVygNDR-----VFVYLRLAGEADAAQDAalaalEAAGHP---VVRIVLD---- 723
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*....
gi 2528069500 575 sttilapelTPAVLGQLIAMYEHSVFTQGVIWGINSFDQWGVELGKELASEILEQLESD 633
Cdd:PRK09533 724 ---------SAEQLGQEFFRWEMATAVAGAVLGINPFDQPDVEASKIKTRELTAAYEKT 773
|
|
| SIS_TAL_PGI |
cd05798 |
SIS_TAL_PGI: Transaldolase (TAL)/ Phosphoglucose isomerase (PGI). This group represents the ... |
456-626 |
4.59e-04 |
|
SIS_TAL_PGI: Transaldolase (TAL)/ Phosphoglucose isomerase (PGI). This group represents the SIS (Sugar ISomerase) PGI domain, of a multifunctional protein (TAL-PGI ) having both TAL and PGI activities. TAL_PGI contains an N-terminal TAL domain and a C-terminal PGI domain. TAL catalyzes the reversible conversion of sedoheptulose-7-phosphate (S7P) and glyceraldehyde-3-phosphate (G3P), to fructose-6-phosphate (F6P) and erythrose-4-phosphate (E4P). PGI catalyzes the reversible isomerization of F6P to glucose-6-phosphate (G6P). It has been suggested for Gluconobacter oxydans TAL_PGI that this enzyme generates E4P and G6P directly from S7P and G3P. G. oxydans TAL_PGI contributes to increased xylitol production from D-arabitol. As xylitol is an alternative natural sweetner to sucrose, the microbial conversion of D-arabitol to xylitol is of interest to food and pharmaceutical industries.
Pssm-ID: 240224 [Multi-domain] Cd Length: 129 Bit Score: 40.51 E-value: 4.59e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 456 LARFPAYLQQLDMESNGKrvrldgspatlrtgsvvwgqpgtngqhafyqllhQGTSIVPVDliafSESVDDEGDHQRKLL 535
Cdd:cd05798 11 IASLGAWLEQLIAESTGK----------------------------------EGKGIIPVD----GEPLGDPAVYGDDRV 52
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2528069500 536 ANVLaqgraLAEGRTAEEAEAAGVPADQVAHrtfpgnrpsTTILAPELTPAVLGQLIAMYEHSVFTQGVIWGINSFDQWG 615
Cdd:cd05798 53 FVYL-----RLAGEADADQEEALLALEAAGH---------PVIRIDLDDAYDLGQEFFRWEMATAVAGAVLGINPFDQPD 118
|
170
....*....|.
gi 2528069500 616 VELGKELASEI 626
Cdd:cd05798 119 VEASKIETRRL 129
|
|
| |
