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Conserved domains on  [gi|2537525202|ref|WP_294091294|]
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TonB-dependent receptor domain-containing protein [Pseudoalteromonas sp.]

Protein Classification

porin family protein( domain architecture ID 229388)

porin family protein is a member of a large superfamily consisting of classical (gram-negative ) porins which are non-specific channels for small hydrophillic molecules, maltoporin-like channels which have specificities for various sugars, and ligand-gated protein channels which cooperate with a TonB associated inner membrane complex to actively transport ligands via the proton motive force

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
OM_channels super family cl21487
Porin superfamily. These outer membrane channels share a beta-barrel structure that differ in ...
 52-975 2.97e-44

Porin superfamily. These outer membrane channels share a beta-barrel structure that differ in strand and shear number. Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20), which associate as trimers. Maltoporin-like channels have specificities for various sugars and form 18 beta-stranded barrels (18,22), which associate as trimers. Ligand-gated protein channels cooperate with a TonB associated inner membrane complex to actively transport ligands via the proton motive force and they form monomeric, (22,24) barrels. The 150-200 N-terminal residues form a plug that blocks the channel from the periplasmic end.


The actual alignment was detected with superfamily member cd01347:

Pssm-ID: 473880 [Multi-domain]  Cd Length: 635  Bit Score: 170.71  E-value: 2.97e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202  52 PLTVLDQDAIKRSGANTIHELLKDLSvfkggsgTFSTSESGGTSTSTPagqsaaSLRGMGPSATLTLINGRRVApssfAA 131
Cdd:cd01347     1 SVSVITAEDIEKQPATSLADLLRRIP-------GVSVTRGGGGGGSTI------SIRGFGPDRTLVLVDGLPLA----SS 63

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 132 GTENFVDVNSIPLAAIERIDILATGASAIYGADAVAGVINYILKDDYQ--GAEVNTSYTNSFDSHDEGKkqlnlvygtni 209
Cdd:cd01347    64 NYGRGVDLNTIPPELIERVEVLKGPSSALYGSGAIGGVVNIITKRPTDefGGSVTAGYGSDNSGSSGGG----------- 132

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 210 gesNLTVFADIYDRNAFKAtdRSYtatpnlvngysylpklenspnvyyyssrdgnelpapncktelvtteygeeicAYYA 289
Cdd:cd01347   133 ---GFDVSGALADDGAFGA--RLY----------------------------------------------------GAYR 155

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 290 NQDDYLETQFESLSTGFMFNSTLGDLDWhtdffysqtkskaysspapinQINDDDgpYIIEDALFIYDNADGSNdlmDQL 369
Cdd:cd01347   156 DGDGTIDGDGQADDSDEERYNVAGKLDW---------------------RPDDDT--RLTLDAGYQDQDADGPG---GTL 209

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 370 YIDPFTTQAgrdmyGFAFDARFNSPRTVEVETKNFRLVSslAGYIGDWSWEsGITFSrskseqeaIDGVYNRYQFHaait 449
Cdd:cd01347   210 PANGTGSSL-----GGGPSSNTNGDRDWDYRDRYRKRAS--LGLEHDLNDT-GWTLR--------ANLSYSYTDND---- 269

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 450 gelcsdgsmatydgtqlncaqgqlmpfYNPFLQGDANNDAVLELAKANPSRSGESTVYGWGLNFNGDLFTFNeLPIYAAF 529
Cdd:cd01347   270 ---------------------------GDPLILNGGNNAAGGDLGRSGYSSERDTTQLGFDAGLNAPFGTGP-VAHTLTL 321

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 530 GIEARREELkdipsldsqaraengylvdvfgfgsslseaDRTQYAAFVELNMPVTEQLELQVAGRYDHYD---------- 599
Cdd:cd01347   322 GVEYRREEL------------------------------DEKQTALYAQDTIELTDDLTLTLGLRYDHYDqdskdtiagg 371

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 600 ----DFGGTFNPKVGLSYRPSDSLIIRSSWSTSFRAPSLTQAGvklrttqssfdcganqavadlycmgdGTEVRVNSLEL 675
Cdd:cd01347   372 ttakKSYSHWSPSLGLVYKLTDGLSLYASYSQGFRAPSLGELY--------------------------GGGSHGGTAAV 425

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 676 GNQTLKAEESEALSIGFAWSPSVNTNLTVDYWHFDHEQVIDTnmtavldraitdaslrhcglvpqgqqgisyeeqlceit 755
Cdd:cd01347   426 GNPNLKPEKSKQYELGLKYDPGDGLTLSAALFRIDIKNEIVS-------------------------------------- 467

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 756 dnaglnieSDGANLSEILTNYIsefnpredelflplfrdhvipleNTGTQTLAGIDFKFDHRF---LFAQGNLTlafdgt 832
Cdd:cd01347   468 --------TPTNTGLGLVTVYV-----------------------NGGKARIRGVELEASYDLtdgLGLTGSYT------ 510

                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 833 hYLEFERNKPGSDATEKLIGTyrYPENVGRFSIDWD--AESYYINLGANYTSSYEDDIEGLRGReideleelgelndelk 910
Cdd:cd01347   511 -YTDTEVKRTDGATTGNRLPG--IPKHTANLGLDYElpDEGLTAGGGVRYRGKQYADTANGNNT---------------- 571

                         890       900       910       920       930       940
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2537525202 911 RDVDEWLVWDLSAGYFINDALSIRARIDNIFDKEPPkLYGSSRGFDSINHNAYGSRYTLSLSYRF 975
Cdd:cd01347   572 VKVPGYTLVDLSASYQFTKNLTLRLGVNNLFDKDYY-TSLSVRGSGLYGYYGPGRTYYLSVSYKF 635
 
Name Accession Description Interval E-value
ligand_gated_channel cd01347
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ...
 52-975 2.97e-44

TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.


Pssm-ID: 238657 [Multi-domain]  Cd Length: 635  Bit Score: 170.71  E-value: 2.97e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202  52 PLTVLDQDAIKRSGANTIHELLKDLSvfkggsgTFSTSESGGTSTSTPagqsaaSLRGMGPSATLTLINGRRVApssfAA 131
Cdd:cd01347     1 SVSVITAEDIEKQPATSLADLLRRIP-------GVSVTRGGGGGGSTI------SIRGFGPDRTLVLVDGLPLA----SS 63

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 132 GTENFVDVNSIPLAAIERIDILATGASAIYGADAVAGVINYILKDDYQ--GAEVNTSYTNSFDSHDEGKkqlnlvygtni 209
Cdd:cd01347    64 NYGRGVDLNTIPPELIERVEVLKGPSSALYGSGAIGGVVNIITKRPTDefGGSVTAGYGSDNSGSSGGG----------- 132

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 210 gesNLTVFADIYDRNAFKAtdRSYtatpnlvngysylpklenspnvyyyssrdgnelpapncktelvtteygeeicAYYA 289
Cdd:cd01347   133 ---GFDVSGALADDGAFGA--RLY----------------------------------------------------GAYR 155

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 290 NQDDYLETQFESLSTGFMFNSTLGDLDWhtdffysqtkskaysspapinQINDDDgpYIIEDALFIYDNADGSNdlmDQL 369
Cdd:cd01347   156 DGDGTIDGDGQADDSDEERYNVAGKLDW---------------------RPDDDT--RLTLDAGYQDQDADGPG---GTL 209

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 370 YIDPFTTQAgrdmyGFAFDARFNSPRTVEVETKNFRLVSslAGYIGDWSWEsGITFSrskseqeaIDGVYNRYQFHaait 449
Cdd:cd01347   210 PANGTGSSL-----GGGPSSNTNGDRDWDYRDRYRKRAS--LGLEHDLNDT-GWTLR--------ANLSYSYTDND---- 269

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 450 gelcsdgsmatydgtqlncaqgqlmpfYNPFLQGDANNDAVLELAKANPSRSGESTVYGWGLNFNGDLFTFNeLPIYAAF 529
Cdd:cd01347   270 ---------------------------GDPLILNGGNNAAGGDLGRSGYSSERDTTQLGFDAGLNAPFGTGP-VAHTLTL 321

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 530 GIEARREELkdipsldsqaraengylvdvfgfgsslseaDRTQYAAFVELNMPVTEQLELQVAGRYDHYD---------- 599
Cdd:cd01347   322 GVEYRREEL------------------------------DEKQTALYAQDTIELTDDLTLTLGLRYDHYDqdskdtiagg 371

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 600 ----DFGGTFNPKVGLSYRPSDSLIIRSSWSTSFRAPSLTQAGvklrttqssfdcganqavadlycmgdGTEVRVNSLEL 675
Cdd:cd01347   372 ttakKSYSHWSPSLGLVYKLTDGLSLYASYSQGFRAPSLGELY--------------------------GGGSHGGTAAV 425

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 676 GNQTLKAEESEALSIGFAWSPSVNTNLTVDYWHFDHEQVIDTnmtavldraitdaslrhcglvpqgqqgisyeeqlceit 755
Cdd:cd01347   426 GNPNLKPEKSKQYELGLKYDPGDGLTLSAALFRIDIKNEIVS-------------------------------------- 467

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 756 dnaglnieSDGANLSEILTNYIsefnpredelflplfrdhvipleNTGTQTLAGIDFKFDHRF---LFAQGNLTlafdgt 832
Cdd:cd01347   468 --------TPTNTGLGLVTVYV-----------------------NGGKARIRGVELEASYDLtdgLGLTGSYT------ 510

                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 833 hYLEFERNKPGSDATEKLIGTyrYPENVGRFSIDWD--AESYYINLGANYTSSYEDDIEGLRGReideleelgelndelk 910
Cdd:cd01347   511 -YTDTEVKRTDGATTGNRLPG--IPKHTANLGLDYElpDEGLTAGGGVRYRGKQYADTANGNNT---------------- 571

                         890       900       910       920       930       940
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2537525202 911 RDVDEWLVWDLSAGYFINDALSIRARIDNIFDKEPPkLYGSSRGFDSINHNAYGSRYTLSLSYRF 975
Cdd:cd01347   572 VKVPGYTLVDLSASYQFTKNLTLRLGVNNLFDKDYY-TSLSVRGSGLYGYYGPGRTYYLSVSYKF 635
FepA COG4771
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and ...
 6-728 9.21e-44

Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism];


Pssm-ID: 443803 [Multi-domain]  Cd Length: 612  Bit Score: 168.88  E-value: 9.21e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202   6 TIAVAISAVLCPVQSVYAQNDQQSEKIERVEVTGSRIKGVDLEGTIPLTVLDQDAIKRSGANTIHELLKDLSvfkggsGT 85
Cdd:COG4771     1 LLLASLLLLLALAAQAADALAEDATELEEVVVTATRTEQSLSDAPASVSVITAEEIEKLGATDLADALRLLP------GV 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202  86 FSTSESGGTSTSTPagqsaaSLRGMGPSATLTLINGRRVAPSSFAagteNFVDVNSIPLAAIERIDILATGASAIYGADA 165
Cdd:COG4771    75 SVTRSGGRGGSSGI------SIRGLGGDRVLVLIDGVPVNNPALG----GGGDLSYIPPDDIERIEVIRGPASALYGSDA 144

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 166 VAGVINYILKD--DYQGAEVNTSYTnsfdSHDEGKKQLNLVYGTNIGESNLTVFADIYDRNAFKATDRSYTATPNLVNGY 243
Cdd:COG4771   145 IGGVINIITKKptDELEGSVSLGYG----SNGNGTYSGSLSLGGPGDKLSFLLSGSYRDRDGYLDYRNGGFVGNSGYERY 220

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 244 SYLPKLEnspnvyyyssrdgnelpapncktelvtteygeeicaYYANQDDYLEtqfeslstgfmfnstlgdldwhtdFFY 323
Cdd:COG4771   221 NLNAKLG------------------------------------YRLSDNHRLS------------------------LSG 240

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 324 SQTKSKAYSSPAPINQINDDDGPYIIEDALFIYDNADgsndlmdqlyidpfttqagrdmygfafdarfnsprtvevetkn 403
Cdd:COG4771   241 GYSRQDRDGGPPTLGDTEISSDNAGDRDTTTDRGNYS------------------------------------------- 277

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 404 frlvsslAGYIGDWSWESGITFSRSKSEQEAIDGVYNRYQfhaaitgelcsdgsmatydgtqlncaqgqlmpfynpflqg 483
Cdd:COG4771   278 -------LRYNGDLGDNLDLSLYYSRTDRDSTNGSLGGST---------------------------------------- 310

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 484 danndavlelakaNPSRSGESTVYGWGLNFNGDLFTFNELpiyaAFGIEARREELKDipsldsqaraengylvdvfGFGS 563
Cdd:COG4771   311 -------------GSFSDSDDTTYGLELDLTYPLGGNHTL----TLGAEYRYDDLDS-------------------SSFL 354

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 564 SLSEADRTQYAAFVELNMPVTEQLELQVAGRYDHYDDFGGT----FNPKVGLSYRPSDSLIIRSSWSTSFRAPSLTQagv 639
Cdd:COG4771   355 GGADASRDTYGLFAQDEWKLTDKLTLTAGLRYDYYSTFGASnytaFSPRLGLRYDLSDNLTLRASYGRGFRAPSLAE--- 431

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 640 klrttqssfdcganqavadlycMGDGTEVRVNSLELGNQTLKAEESEALSIGFAWSPSVNT-NLTVDYWHFDHEQVIDTN 718
Cdd:COG4771   432 ----------------------LYGSGTGTPGRYVLGNPDLKPETSDNYELGLEYRLGNGGlSLSLTGFYTDIKDLIVLV 489

                         730
                  ....*....|
gi 2537525202 719 MTAVLDRAIT 728
Cdd:COG4771   490 PVGPGPGDVL 499
TonB_dep_Rec pfam00593
TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
 496-974 1.69e-26

TonB dependent receptor; This model now only covers the conserved part of the barrel structure.


Pssm-ID: 395474 [Multi-domain]  Cd Length: 475  Bit Score: 114.48  E-value: 1.69e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 496 ANPSRSGESTVYGWGLNFNGDLFTFNELPIYAAFGIEARREELkdipSLDSQARAENGYLVDVFGFGSSLSEADRTQYAA 575
Cdd:pfam00593 102 SGAGDYLSDDRLYGLYGLDGDLELSLDLSHDLLLGVELRTAGL----DYRRLDDDAYDPYDPANPSSSSYSDTTTDSYGL 177

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 576 FVELNMPVTEQLELQVAGRYDHYDDFGGT--------------FNPKVGLSYRPSDSLIIRSSWSTSFRAPSLtqagvkl 641
Cdd:pfam00593 178 YLQDNIKLTDRLTLTLGLRYDHYSTDGDDgngggdnfsrsysaFSPRLGLVYKPTDNLSLYASYSRGFRAPSL------- 250

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 642 rttqssfdcganqavADLYcmGDGTEVRVNSLELGNQTLKAEESEALSIGFAWSPSvNTNLTVDYWHFDHEQVIDTNMTA 721
Cdd:pfam00593 251 ---------------GELY--GSGSGGGGGAVAGGNPDLKPETSDNYELGLKYDDG-RLSLSLALFYIDIKNLITSDPDG 312

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 722 vldraitdaslrhcglvpqgqqgisyeeqlceitdnaglniesdganlseiltnyisefnpredelflPLFRDHVIPLEN 801
Cdd:pfam00593 313 --------------------------------------------------------------------PGLGGTVYTYTN 324

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 802 TGTQTLAGIDFKFDHRFLfaqgNLTLAFDGTHYLEFERNKPGSDATEKLIGTyryPENVGRFSIDWD--AESYYINLGAN 879
Cdd:pfam00593 325 VGKARIRGVELELSGRLW----GLGLSGGGYTYTDADDDADADDTGNPLPNV---PRHTANLGLTYDfpLGGWGARLGAR 397

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 880 YTSSYEDDIeglrgreideleelgeLNDELKRDVDEWLVWDLSAGYFINDALSIRARIDNIFDKEPPKlYGSSRGFDSIN 959
Cdd:pfam00593 398 YVGSGERRY----------------GDAANTFKTPGYTLVDLSAGYRLNKNLTLRLGVNNLFDKYYKR-YYSSGGGNLGG 460

                         490
                  ....*....|....*
gi 2537525202 960 HNAYGSRYTLSLSYR 974
Cdd:pfam00593 461 YPGPGRTFYLGLSYK 475
PRK10064 PRK10064
catecholate siderophore receptor CirA; Provisional
 29-975 7.72e-16

catecholate siderophore receptor CirA; Provisional


Pssm-ID: 236646 [Multi-domain]  Cd Length: 663  Bit Score: 82.24  E-value: 7.72e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202  29 SEKIERVEVTGSRIKGVDLEGTIPLTVLDQDAIKRSGANTIHELLKDLSvfkggsgtfstsesGGTSTSTPAGQSAASLR 108
Cdd:PRK10064   27 DDDGETMVVTASAVEQNLKDAPASISVITQEDLQRKPVQNLKDVLKEVP--------------GVQLTNEGDNRKGVSIR 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 109 GMGPSATLTLINGRRVApSSFAAGTENFVDVNSIPLAAIERIDILATGASAIYGADAVAGVINYILKddyqgaEVNTSYT 188
Cdd:PRK10064   93 GLDSSYTLILIDGKRVN-SRNAVFRHNDFDLNWIPVDAIERIEVVRGPMSSLYGSDALGGVVNIITK------KIGQKWH 165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 189 NSFDSHdegkkqlnlvygTNIGEsnltvfadiydrnafkatDRSYTATPNLvNGYSYLPKLENSPNVYYYSSRDGNELPA 268
Cdd:PRK10064  166 GTVTVD------------TTIQE------------------HRDRGDTYNG-QFFTSGPLIDGVLGMKAYGSLAKREKDD 214

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 269 PNCKTelvTTEYGEEicayyanqdDYLEtqfeslstGFMFNstlgdlDWHTDFFYSQTKSKAYSspapinqindddgpyi 348
Cdd:PRK10064  215 PQNST---TTDTGET---------PRIE--------GFTSR------DGNVEFAWTPNQNHDFT---------------- 252

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 349 iedALFIYDNADGSNDLMDQLYIDpfttqagRDMYGFAFDARF---NSPRTV---EVETKNfrlvsslagyigdwswesG 422
Cdd:PRK10064  253 ---AGYGFDRQDRDSDSLDKNRLE-------RQNYSLSHNGRWdygNSELKYygeKVENKN------------------P 304

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 423 ITFSRSKSEQEAIDGVYnryqfhaaitgelcsdgsmatydgtqlncaqgqlmpfynpflqgdanndaVLELAKANpsrsg 502
Cdd:PRK10064  305 GNSSPITSESNSIDGKY--------------------------------------------------TLPLTAIN----- 329

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 503 estvygwglnfngDLFTFnelpiyaafGIEARREELKDIPSLDsqaraengylvdvfgfGSSLSEADRTQYAAFVELNMP 582
Cdd:PRK10064  330 -------------QFLTF---------GGEWRHDKLSDAVNLT----------------GGTSSKTSASQYALFVEDEWR 371

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 583 VTEQLELQVAGRYDHYDDFGGTFNPKVGLSYRPSDSLIIRSSWSTSFRAPSLTQagvkLRTTQSSFDCGANQAVadlycm 662
Cdd:PRK10064  372 IFEPLALTTGVRMDDHETYGDHWSPRAYLVYNATDTVTVKGGWATAFKAPSLLQ----LSPDWTSNSCRGACKI------ 441

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 663 gdgtevrvnsleLGNQTLKAEESEALSIGF------AWSPSVNTNLTVdyWHFDHEQVIDTNMTAvldraitdaslrhcg 736
Cdd:PRK10064  442 ------------VGSPDLKPETSESWELGLyymgeeGWLEGVESSVTV--FRNDVDDRISISRTS--------------- 492

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 737 lvpqgqqgisyeeqlceitdnaglniesdGANLSEILTNYISeFNPREDELFLPLFRdhvipLENTGTQTLAGIDFKFdh 816
Cdd:PRK10064  493 -----------------------------DVNAAPGYQNFVG-FETNGRGRRVPVFR-----YYNVNKARIQGVETEL-- 535

                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 817 RFLFAQG-NLTLAF---DGTHyLEFERNKPGSDatekligtyrYPENVGRFSIDWD---AESYYINLGANYTSSYEDDie 889
Cdd:PRK10064  536 KIPFNDEwKLSLNYtynDGRD-VSNGENKPLSD----------LPFHTANGTLDWKplaLEDWSFYVSGNYTGQKRAD-- 602

                         890       900       910       920       930       940       950       960
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 890 glrgreideleelgelnDELKRDVDEWLVWDLSAGYFINDALSIRARIDNIFDKEPPKlygssrgfDSINHNAYGSRYTL 969
Cdd:PRK10064  603 -----------------SATAKTPGGYTIWNTGAAWQVTKDVKLRAGVLNLGDKDLSR--------DDYSYNEDGRRYFM 657


                  ....*.
gi 2537525202 970 SLSYRF 975
Cdd:PRK10064  658 AVDYRF 663
TonB-siderophor TIGR01783
TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of ...
 54-176 5.22e-06

TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of TonB-dependent outer membrane siderophore receptors. It has no overlap with TonB receptors known to transport other substances, but is likely incomplete due to lack of characterizations. It is likely that genuine siderophore receptors will be identified which score below the noise cutoff to this model at which point the model should be updated. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273805 [Multi-domain]  Cd Length: 651  Bit Score: 50.49  E-value: 5.22e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202  54 TVLDQDAIKRSGANTIHELLKDLSvfkggSGTFSTSESGGTStstpagqSAASLRGMGPSATL--TLINGRR-VAPSSFA 130
Cdd:TIGR01783   7 SVITRQELEDQQAGSLSEALQRVP-----GVVVGGSGGTTQF-------GNITIRGFGLEVDIdnVYLDGVPlLSRGNLA 74

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 2537525202 131 agtenfvdvnSIPLAAIERIDILATGASAIYGADAVAGVINYILKD 176
Cdd:TIGR01783  75 ----------IVDPAMVERVEVLRGPASLLYGGSAPGGVINIVTKR 110
 
Name Accession Description Interval E-value
ligand_gated_channel cd01347
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ...
 52-975 2.97e-44

TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.


Pssm-ID: 238657 [Multi-domain]  Cd Length: 635  Bit Score: 170.71  E-value: 2.97e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202  52 PLTVLDQDAIKRSGANTIHELLKDLSvfkggsgTFSTSESGGTSTSTPagqsaaSLRGMGPSATLTLINGRRVApssfAA 131
Cdd:cd01347     1 SVSVITAEDIEKQPATSLADLLRRIP-------GVSVTRGGGGGGSTI------SIRGFGPDRTLVLVDGLPLA----SS 63

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 132 GTENFVDVNSIPLAAIERIDILATGASAIYGADAVAGVINYILKDDYQ--GAEVNTSYTNSFDSHDEGKkqlnlvygtni 209
Cdd:cd01347    64 NYGRGVDLNTIPPELIERVEVLKGPSSALYGSGAIGGVVNIITKRPTDefGGSVTAGYGSDNSGSSGGG----------- 132

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 210 gesNLTVFADIYDRNAFKAtdRSYtatpnlvngysylpklenspnvyyyssrdgnelpapncktelvtteygeeicAYYA 289
Cdd:cd01347   133 ---GFDVSGALADDGAFGA--RLY----------------------------------------------------GAYR 155

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 290 NQDDYLETQFESLSTGFMFNSTLGDLDWhtdffysqtkskaysspapinQINDDDgpYIIEDALFIYDNADGSNdlmDQL 369
Cdd:cd01347   156 DGDGTIDGDGQADDSDEERYNVAGKLDW---------------------RPDDDT--RLTLDAGYQDQDADGPG---GTL 209

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 370 YIDPFTTQAgrdmyGFAFDARFNSPRTVEVETKNFRLVSslAGYIGDWSWEsGITFSrskseqeaIDGVYNRYQFHaait 449
Cdd:cd01347   210 PANGTGSSL-----GGGPSSNTNGDRDWDYRDRYRKRAS--LGLEHDLNDT-GWTLR--------ANLSYSYTDND---- 269

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 450 gelcsdgsmatydgtqlncaqgqlmpfYNPFLQGDANNDAVLELAKANPSRSGESTVYGWGLNFNGDLFTFNeLPIYAAF 529
Cdd:cd01347   270 ---------------------------GDPLILNGGNNAAGGDLGRSGYSSERDTTQLGFDAGLNAPFGTGP-VAHTLTL 321

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 530 GIEARREELkdipsldsqaraengylvdvfgfgsslseaDRTQYAAFVELNMPVTEQLELQVAGRYDHYD---------- 599
Cdd:cd01347   322 GVEYRREEL------------------------------DEKQTALYAQDTIELTDDLTLTLGLRYDHYDqdskdtiagg 371

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 600 ----DFGGTFNPKVGLSYRPSDSLIIRSSWSTSFRAPSLTQAGvklrttqssfdcganqavadlycmgdGTEVRVNSLEL 675
Cdd:cd01347   372 ttakKSYSHWSPSLGLVYKLTDGLSLYASYSQGFRAPSLGELY--------------------------GGGSHGGTAAV 425

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 676 GNQTLKAEESEALSIGFAWSPSVNTNLTVDYWHFDHEQVIDTnmtavldraitdaslrhcglvpqgqqgisyeeqlceit 755
Cdd:cd01347   426 GNPNLKPEKSKQYELGLKYDPGDGLTLSAALFRIDIKNEIVS-------------------------------------- 467

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 756 dnaglnieSDGANLSEILTNYIsefnpredelflplfrdhvipleNTGTQTLAGIDFKFDHRF---LFAQGNLTlafdgt 832
Cdd:cd01347   468 --------TPTNTGLGLVTVYV-----------------------NGGKARIRGVELEASYDLtdgLGLTGSYT------ 510

                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 833 hYLEFERNKPGSDATEKLIGTyrYPENVGRFSIDWD--AESYYINLGANYTSSYEDDIEGLRGReideleelgelndelk 910
Cdd:cd01347   511 -YTDTEVKRTDGATTGNRLPG--IPKHTANLGLDYElpDEGLTAGGGVRYRGKQYADTANGNNT---------------- 571

                         890       900       910       920       930       940
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2537525202 911 RDVDEWLVWDLSAGYFINDALSIRARIDNIFDKEPPkLYGSSRGFDSINHNAYGSRYTLSLSYRF 975
Cdd:cd01347   572 VKVPGYTLVDLSASYQFTKNLTLRLGVNNLFDKDYY-TSLSVRGSGLYGYYGPGRTYYLSVSYKF 635
FepA COG4771
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and ...
 6-728 9.21e-44

Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism];


Pssm-ID: 443803 [Multi-domain]  Cd Length: 612  Bit Score: 168.88  E-value: 9.21e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202   6 TIAVAISAVLCPVQSVYAQNDQQSEKIERVEVTGSRIKGVDLEGTIPLTVLDQDAIKRSGANTIHELLKDLSvfkggsGT 85
Cdd:COG4771     1 LLLASLLLLLALAAQAADALAEDATELEEVVVTATRTEQSLSDAPASVSVITAEEIEKLGATDLADALRLLP------GV 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202  86 FSTSESGGTSTSTPagqsaaSLRGMGPSATLTLINGRRVAPSSFAagteNFVDVNSIPLAAIERIDILATGASAIYGADA 165
Cdd:COG4771    75 SVTRSGGRGGSSGI------SIRGLGGDRVLVLIDGVPVNNPALG----GGGDLSYIPPDDIERIEVIRGPASALYGSDA 144

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 166 VAGVINYILKD--DYQGAEVNTSYTnsfdSHDEGKKQLNLVYGTNIGESNLTVFADIYDRNAFKATDRSYTATPNLVNGY 243
Cdd:COG4771   145 IGGVINIITKKptDELEGSVSLGYG----SNGNGTYSGSLSLGGPGDKLSFLLSGSYRDRDGYLDYRNGGFVGNSGYERY 220

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 244 SYLPKLEnspnvyyyssrdgnelpapncktelvtteygeeicaYYANQDDYLEtqfeslstgfmfnstlgdldwhtdFFY 323
Cdd:COG4771   221 NLNAKLG------------------------------------YRLSDNHRLS------------------------LSG 240

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 324 SQTKSKAYSSPAPINQINDDDGPYIIEDALFIYDNADgsndlmdqlyidpfttqagrdmygfafdarfnsprtvevetkn 403
Cdd:COG4771   241 GYSRQDRDGGPPTLGDTEISSDNAGDRDTTTDRGNYS------------------------------------------- 277

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 404 frlvsslAGYIGDWSWESGITFSRSKSEQEAIDGVYNRYQfhaaitgelcsdgsmatydgtqlncaqgqlmpfynpflqg 483
Cdd:COG4771   278 -------LRYNGDLGDNLDLSLYYSRTDRDSTNGSLGGST---------------------------------------- 310

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 484 danndavlelakaNPSRSGESTVYGWGLNFNGDLFTFNELpiyaAFGIEARREELKDipsldsqaraengylvdvfGFGS 563
Cdd:COG4771   311 -------------GSFSDSDDTTYGLELDLTYPLGGNHTL----TLGAEYRYDDLDS-------------------SSFL 354

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 564 SLSEADRTQYAAFVELNMPVTEQLELQVAGRYDHYDDFGGT----FNPKVGLSYRPSDSLIIRSSWSTSFRAPSLTQagv 639
Cdd:COG4771   355 GGADASRDTYGLFAQDEWKLTDKLTLTAGLRYDYYSTFGASnytaFSPRLGLRYDLSDNLTLRASYGRGFRAPSLAE--- 431

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 640 klrttqssfdcganqavadlycMGDGTEVRVNSLELGNQTLKAEESEALSIGFAWSPSVNT-NLTVDYWHFDHEQVIDTN 718
Cdd:COG4771   432 ----------------------LYGSGTGTPGRYVLGNPDLKPETSDNYELGLEYRLGNGGlSLSLTGFYTDIKDLIVLV 489

                         730
                  ....*....|
gi 2537525202 719 MTAVLDRAIT 728
Cdd:COG4771   490 PVGPGPGDVL 499
BtuB COG4206
Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism];
35-317 2.74e-27

Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism];


Pssm-ID: 443355 [Multi-domain]  Cd Length: 276  Bit Score: 112.66  E-value: 2.74e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202  35 VEVTGSRIKGVDLEGTIPLTVLDQDAIKRSGANTIHELLKDLSvfkggsGtFSTSESGGtststPAGQSAASLRGMGPSA 114
Cdd:COG4206     1 VVVTATRLEQSKSDLTGSVTVIDAEELERSGATSLADALRRVP------G-VQVSSSGG-----PGSAASISIRGLGSNQ 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 115 TLTLINGRRVAPSSFaagteNFVDVNSIPLAAIERIDILATGASAIYGADAVAGVINYILKDDYQGAEVNTSYT-NSFDS 193
Cdd:COG4206    69 TLVLIDGVPLNDPSL-----GGVDLSLIPPDDIERIEVLKGAASALYGSDAIGGVINITTKKGKKGFKGSVSASyGSFGT 143

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 194 HdegkkQLNLVYGTNIGESNLTVFADIYDRNAFKATDRSYTATP-----NLVNGYSYLPKLENSPNVYYYSSRDGNELPA 268
Cdd:COG4206   144 R-----RLSASLSGGAGKFSYSLSASYRRSDGYRYNDPDLRNNDgyentSLNARLGYKLGDNGSLSLSGGYSDSERGYPG 218

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2537525202 269 PNCKTELVT---------TEYGEEICAYYANQDDYLETQFESLSTGFMFNSTLGDLDW 317
Cdd:COG4206   219 AVGSDRNLRlslsleyklSDGWSLLLLAYYYYDRDYEDGGGDSAGTSNTDGARAGLSY 276
TonB_dep_Rec pfam00593
TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
 496-974 1.69e-26

TonB dependent receptor; This model now only covers the conserved part of the barrel structure.


Pssm-ID: 395474 [Multi-domain]  Cd Length: 475  Bit Score: 114.48  E-value: 1.69e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 496 ANPSRSGESTVYGWGLNFNGDLFTFNELPIYAAFGIEARREELkdipSLDSQARAENGYLVDVFGFGSSLSEADRTQYAA 575
Cdd:pfam00593 102 SGAGDYLSDDRLYGLYGLDGDLELSLDLSHDLLLGVELRTAGL----DYRRLDDDAYDPYDPANPSSSSYSDTTTDSYGL 177

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 576 FVELNMPVTEQLELQVAGRYDHYDDFGGT--------------FNPKVGLSYRPSDSLIIRSSWSTSFRAPSLtqagvkl 641
Cdd:pfam00593 178 YLQDNIKLTDRLTLTLGLRYDHYSTDGDDgngggdnfsrsysaFSPRLGLVYKPTDNLSLYASYSRGFRAPSL------- 250

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 642 rttqssfdcganqavADLYcmGDGTEVRVNSLELGNQTLKAEESEALSIGFAWSPSvNTNLTVDYWHFDHEQVIDTNMTA 721
Cdd:pfam00593 251 ---------------GELY--GSGSGGGGGAVAGGNPDLKPETSDNYELGLKYDDG-RLSLSLALFYIDIKNLITSDPDG 312

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 722 vldraitdaslrhcglvpqgqqgisyeeqlceitdnaglniesdganlseiltnyisefnpredelflPLFRDHVIPLEN 801
Cdd:pfam00593 313 --------------------------------------------------------------------PGLGGTVYTYTN 324

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 802 TGTQTLAGIDFKFDHRFLfaqgNLTLAFDGTHYLEFERNKPGSDATEKLIGTyryPENVGRFSIDWD--AESYYINLGAN 879
Cdd:pfam00593 325 VGKARIRGVELELSGRLW----GLGLSGGGYTYTDADDDADADDTGNPLPNV---PRHTANLGLTYDfpLGGWGARLGAR 397

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 880 YTSSYEDDIeglrgreideleelgeLNDELKRDVDEWLVWDLSAGYFINDALSIRARIDNIFDKEPPKlYGSSRGFDSIN 959
Cdd:pfam00593 398 YVGSGERRY----------------GDAANTFKTPGYTLVDLSAGYRLNKNLTLRLGVNNLFDKYYKR-YYSSGGGNLGG 460

                         490
                  ....*....|....*
gi 2537525202 960 HNAYGSRYTLSLSYR 974
Cdd:pfam00593 461 YPGPGRTFYLGLSYK 475
CirA COG1629
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];
32-944 2.39e-23

Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];


Pssm-ID: 441236 [Multi-domain]  Cd Length: 644  Bit Score: 106.07  E-value: 2.39e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202  32 IERVEVTGSRIKGVDLEGTIPLTVLDQDAIKRSGANTIHELLKDLSvfkggsGTFSTSESGGtststpagQSAASLRGMG 111
Cdd:COG1629     1 LEEVVVTATRTDESLQDVPGSVSVISREQLEDQPATDLGDLLRRVP------GVSVTSAGGG--------AGQISIRGFG 66

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 112 --PSATLTLINGRRVAPSSFAAGtenfvDVNSIPLAAIERIDILATGASAIYGADAVAGVINYILKD--DYQGAEVNTSY 187
Cdd:COG1629    67 ggGNRVLVLVDGVPLNDPSGGDG-----GLSYIDPEDIERVEVLRGPSSALYGSGALGGVINIVTKKpkDGKGGEVSASY 141

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 188 tNSFdshdeGKKQLNLVYGTNIGESNLTVFADIYDRNAFKATDRSytatpnlvNGYSYLPKLENSPN------VYYYSSR 261
Cdd:COG1629   142 -GSY-----GTYRASLSLSGGNGKLAYRLSASYRDSDGYRDNSDS--------DRYNLRAKLGYQLGddtrltLSASYSD 207

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 262 DGNELPAPNCKTELVTTEYGEEicAYYANQDDYLETQFESLSTGFMFNSTLGDLDWHTDFFYSqtkskaysspapinqin 341
Cdd:COG1629   208 SDQDSPGYLTLAALRPRGAMDD--GTNPYSNDTDDNTRDRYSLSLEYEHLGDGLKLSASAYYR----------------- 268

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 342 dddgpyiiedalfiYDNADGSNDLMDQLYIDPFTTQAGRDMYGFAFDARFNSPRTVEvetknfrlvsslagyiGDWSWES 421
Cdd:COG1629   269 --------------YDDTDLDSDFTPTPADGGTLEQTDFDNRTYGLELRLTYDLGFG----------------GKHTLLV 318

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 422 GITFSRSKSEQeaidgvynryqfhaaitgelcsdgsmatyDGTQLNCAQGQLMPFYNPFLQgdanndavlelakanpsrs 501
Cdd:COG1629   319 GLDYQRQDLDG-----------------------------SGYPLDLGSGSLPTLTSGADD------------------- 350

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 502 gestvygwglnfngdlftfnelpiyaafgiearreelkdipsldsqaraengylvdvfgfgsslsEADRTQYAAFVELNM 581
Cdd:COG1629   351 -----------------------------------------------------------------DGTTTSLALYAQDTY 365

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 582 PVTEQLELQVAGRYDHY-----DDFGGT-----------FNPKVGLSYRPSDSLIIRSSWSTSFRAPSltqagvklrttq 645
Cdd:COG1629   366 KLTDKLTLTAGLRYDYVsydvdDTVTGTdsasgsrsysaFSPSLGLTYQLSPNLSLYASYSRGFRAPT------------ 433

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 646 ssfdcganqaVADLYCMGdgtevrVNSLELGNQTLKAEESEALSIGFAWSPSVNT-NLTVDYWHFDHEQVIDTnmtavld 724
Cdd:COG1629   434 ----------FGELYANG------TDPYSVGNPDLKPETSTNYELGLRYRLLDGRlSLSLALFYSDVDNEILS------- 490

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 725 raitdaslrhcglvpqgqQGISYEEQLCEITDNAGlNIESDGANLSeiltnyisefnpredelflplfrdhviplentgt 804
Cdd:COG1629   491 ------------------VPLPNDSGFSTYYTNAG-KARSYGVELE---------------------------------- 517

                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 805 qtlagIDFKFDHRFlfaqgNLTLAFDGTHYlefeRNKPGSDATEKLIGTY--RYPENVGRFSIDWDAES-YYINLGANYT 881
Cdd:COG1629   518 -----LSYQLTPGL-----SLNASYSYTDA----KFDDDTDGSADLDGNRlpGVPPLTANLGLTYEFPGgWSLGLGVRYV 583

                         890       900       910       920       930       940
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2537525202 882 SSYEDDieglrgreideleelgELNDElkRDVDEWLVWDLSAGYFINDALSIRARIDNIFDKE 944
Cdd:COG1629   584 GDRYLD----------------DANTQ--GAPGGYTLVDLGAGYRFGDNLTLSLGVDNLFDKK 628
Plug pfam07715
TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently ...
 48-169 1.18e-18

TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently folding subunit of the TonB-dependent receptors. It acts as the channel gate, blocking the pore until the channel is bound by ligand. At this point it under goes conformational changes opens the channel.


Pssm-ID: 462243 [Multi-domain]  Cd Length: 107  Bit Score: 82.32  E-value: 1.18e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202  48 EGTIPLTVLDQDAIKRSGANTIHELLKDLSvfkggsGTFSTSESGGtststpaGQSAASLRGMGPSATLTLINGRRVAPS 127
Cdd:pfam07715   4 DTPGSVSVVTAEDIEDQGATNLADALRGVP------GVSVSSGGGG-------GGSSISIRGFGSNRVLVLVDGVPLNSG 70

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 2537525202 128 SFaagteNFVDVNSIPLAAIERIDILATGASAIYGADAVAGV 169
Cdd:pfam07715  71 GG-----GSVDLNSIDPEDIERVEVLKGPASALYGSGAIGGV 107
FecA COG4772
Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];
13-975 7.07e-16

Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];


Pssm-ID: 443804 [Multi-domain]  Cd Length: 681  Bit Score: 82.28  E-value: 7.07e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202  13 AVLCPVQSVYAQndQQSEKIERVEVTGSRIKGVDLE---GTIplTVLDQDAIKRSGANTIHELLKDLSvfkggsGTFSTS 89
Cdd:COG4772     6 AAALLLAAAAAA--EAATTLETVVVTGSRAAEARLKdvpGSV--SVVDREELENQAATSLREVLRRVP------GVNVQE 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202  90 ESGgtststpAGQSAA-SLRGMGPSAT---LTLINGRRVAPSSFAAGTENFvdvnSIPLAAIERIDILATGASAIYGADA 165
Cdd:COG4772    76 EDG-------FGLRPNiGIRGLGPRRSrgiTLLEDGIPIAPAPYGDPAAYY----FPDLERMERIEVLRGAAALRYGPQT 144

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 166 VAGVINYILKDDYQGAEVNTSytNSFDSHdeGKKQLNLVYGTNIGESNLTVFADIYDRNAFK---ATDRsytatpNLVNG 242
Cdd:COG4772   145 VGGAINFVTRTIPTAFGGELR--VTGGSF--GYRRTHASVGGTVGNFGYLVEYSRKRGDGFRdnsGFDI------NDFNA 214

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 243 ysylpKLEnspnvyyYSSRDGNELpapncktelvTTEYGeeicAYYANQDDYLetqfeslstgfmfnsTLGDLDWHTDff 322
Cdd:COG4772   215 -----KLG-------YRLSDRQEL----------TLKFQ----YYDEDANTPG---------------GLTDAQFDAD-- 251

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 323 ysqtkskAYSSPAPINQINDDdgpyiiedalfiydnadgsndlmdqlyidpfttqagRDMYGFAFDARFNSprTVEVETK 402
Cdd:COG4772   252 -------PRQSYRPADQFDTR------------------------------------RTQLSLRYEHQLSD--NTTLTTT 286

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 403 NFRLVSSLagyigDWSWEsgitFSRSKSEQEAIDGVYNRYQFHaaitgelcsdgsmatYDGTQLNcaqgqlmpfynpflq 482
Cdd:COG4772   287 AYYNDFSR-----NWYIR----QNTADPNTPGLGLRGNPRGYR---------------SYGIEPR--------------- 327

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 483 gdanndavlelakanpsrsgestvygwgLNFNGDLF-TFNELpiyaAFGIEARREELKDIpsldsqaRAENGYLVDVFGF 561
Cdd:COG4772   328 ----------------------------LTHRFELGgVPHTL----EVGLRYHREEEDRK-------QYVNTYGQGRSGA 368

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 562 GSSLSEADRTQ-YAAFVELNMPVTEQLELQVAGRYDH----YDDFGGT--------------FNPKVGLSYRPSDSLIIR 622
Cdd:COG4772   369 GLRRDRRFSADaLAAYAQNRFELTGRLTLTPGLRYEHirrdRTDRYSTrtggddsgsnsyseFLPGLGLLYQLTDNLQLY 448

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 623 SSWSTSFRAPSLTQAGVklrttqssfdcganqavadlycmGDGtevrvnslelGNQTLKAEESEALSIGFAWSPSVNTNL 702
Cdd:COG4772   449 ANVSRGFEPPTFGDLAY-----------------------GNG----------GNPDLKPEKSWNYELGTRGRIGNGLSA 495

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 703 TVDYWH--FDHEQVIDTNMTAVLDraitdaslrhcglvpqgqqgisyeeqlceITDNAGlNIESDGANLSeiltnyiSEF 780
Cdd:COG4772   496 EVALFYidYDNELGSCSAAGGDRS-----------------------------TFTNAG-ETRHQGLELA-------LDY 538

                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 781 NPREDELF-LPLFrdhviplentgtQTLAGIDFKFDHRFLFAQGNLTLAFdgthylefernkpgsdatekligtyrYPEN 859
Cdd:COG4772   539 DLLKGGGLgLPLF------------AAYTYTDAEFTSDFGPVFAGNRLPY--------------------------VPRH 580

                         890       900       910       920       930       940       950       960
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 860 VGRFSIDWDAESYYINLGANYTSSYEDDIEGLRGREIDELeelgelndelkrdVDEWLVWDLSAGYFINDALSIRARIDN 939
Cdd:COG4772   581 QLTAGLGYEHGGWTANLNGRYVSEQFTDAANTVADGSFGK-------------IPSYTVLDLSASYDFGKNLSLFAGVNN 647

                         970       980       990      1000
                  ....*....|....*....|....*....|....*....|..
gi 2537525202 940 IFDKEppklYGSSRgfdsINHNAYGSR------YTLSLSYRF 975
Cdd:COG4772   648 LFDKR----YIASR----APNYAAGIRpgpprtVYAGLRLKF 681
PRK10064 PRK10064
catecholate siderophore receptor CirA; Provisional
 29-975 7.72e-16

catecholate siderophore receptor CirA; Provisional


Pssm-ID: 236646 [Multi-domain]  Cd Length: 663  Bit Score: 82.24  E-value: 7.72e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202  29 SEKIERVEVTGSRIKGVDLEGTIPLTVLDQDAIKRSGANTIHELLKDLSvfkggsgtfstsesGGTSTSTPAGQSAASLR 108
Cdd:PRK10064   27 DDDGETMVVTASAVEQNLKDAPASISVITQEDLQRKPVQNLKDVLKEVP--------------GVQLTNEGDNRKGVSIR 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 109 GMGPSATLTLINGRRVApSSFAAGTENFVDVNSIPLAAIERIDILATGASAIYGADAVAGVINYILKddyqgaEVNTSYT 188
Cdd:PRK10064   93 GLDSSYTLILIDGKRVN-SRNAVFRHNDFDLNWIPVDAIERIEVVRGPMSSLYGSDALGGVVNIITK------KIGQKWH 165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 189 NSFDSHdegkkqlnlvygTNIGEsnltvfadiydrnafkatDRSYTATPNLvNGYSYLPKLENSPNVYYYSSRDGNELPA 268
Cdd:PRK10064  166 GTVTVD------------TTIQE------------------HRDRGDTYNG-QFFTSGPLIDGVLGMKAYGSLAKREKDD 214

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 269 PNCKTelvTTEYGEEicayyanqdDYLEtqfeslstGFMFNstlgdlDWHTDFFYSQTKSKAYSspapinqindddgpyi 348
Cdd:PRK10064  215 PQNST---TTDTGET---------PRIE--------GFTSR------DGNVEFAWTPNQNHDFT---------------- 252

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 349 iedALFIYDNADGSNDLMDQLYIDpfttqagRDMYGFAFDARF---NSPRTV---EVETKNfrlvsslagyigdwswesG 422
Cdd:PRK10064  253 ---AGYGFDRQDRDSDSLDKNRLE-------RQNYSLSHNGRWdygNSELKYygeKVENKN------------------P 304

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 423 ITFSRSKSEQEAIDGVYnryqfhaaitgelcsdgsmatydgtqlncaqgqlmpfynpflqgdanndaVLELAKANpsrsg 502
Cdd:PRK10064  305 GNSSPITSESNSIDGKY--------------------------------------------------TLPLTAIN----- 329

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 503 estvygwglnfngDLFTFnelpiyaafGIEARREELKDIPSLDsqaraengylvdvfgfGSSLSEADRTQYAAFVELNMP 582
Cdd:PRK10064  330 -------------QFLTF---------GGEWRHDKLSDAVNLT----------------GGTSSKTSASQYALFVEDEWR 371

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 583 VTEQLELQVAGRYDHYDDFGGTFNPKVGLSYRPSDSLIIRSSWSTSFRAPSLTQagvkLRTTQSSFDCGANQAVadlycm 662
Cdd:PRK10064  372 IFEPLALTTGVRMDDHETYGDHWSPRAYLVYNATDTVTVKGGWATAFKAPSLLQ----LSPDWTSNSCRGACKI------ 441

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 663 gdgtevrvnsleLGNQTLKAEESEALSIGF------AWSPSVNTNLTVdyWHFDHEQVIDTNMTAvldraitdaslrhcg 736
Cdd:PRK10064  442 ------------VGSPDLKPETSESWELGLyymgeeGWLEGVESSVTV--FRNDVDDRISISRTS--------------- 492

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 737 lvpqgqqgisyeeqlceitdnaglniesdGANLSEILTNYISeFNPREDELFLPLFRdhvipLENTGTQTLAGIDFKFdh 816
Cdd:PRK10064  493 -----------------------------DVNAAPGYQNFVG-FETNGRGRRVPVFR-----YYNVNKARIQGVETEL-- 535

                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 817 RFLFAQG-NLTLAF---DGTHyLEFERNKPGSDatekligtyrYPENVGRFSIDWD---AESYYINLGANYTSSYEDDie 889
Cdd:PRK10064  536 KIPFNDEwKLSLNYtynDGRD-VSNGENKPLSD----------LPFHTANGTLDWKplaLEDWSFYVSGNYTGQKRAD-- 602

                         890       900       910       920       930       940       950       960
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 890 glrgreideleelgelnDELKRDVDEWLVWDLSAGYFINDALSIRARIDNIFDKEPPKlygssrgfDSINHNAYGSRYTL 969
Cdd:PRK10064  603 -----------------SATAKTPGGYTIWNTGAAWQVTKDVKLRAGVLNLGDKDLSR--------DDYSYNEDGRRYFM 657


                  ....*.
gi 2537525202 970 SLSYRF 975
Cdd:PRK10064  658 AVDYRF 663
PRK13524 PRK13524
FepA family TonB-dependent siderophore receptor;
2-944 9.35e-14

FepA family TonB-dependent siderophore receptor;


Pssm-ID: 237410 [Multi-domain]  Cd Length: 744  Bit Score: 75.45  E-value: 9.35e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202   2 FRQLTIAVAISAVLCPVQSVYAQNDQQSE---KIERVEVTGSRIK----GVdlegtiplTVLDQDAI-KRSGANTIHELL 73
Cdd:PRK13524    5 IHSLALLVNLGIYGVAQAAEAEDAKTDDTpasHEDTIVVTAAEQNlqapGV--------STITAEDIrKRPPANDVSEII 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202  74 KDLSvfkggsGTFSTsesgGTSTSTPAG-QSAASLRGMGPSATLTLINGRRVapssfaaGTENFV------------DVN 140
Cdd:PRK13524   77 RTMP------GVNLT----GNSTSGQRGnNRQIDIRGMGPENTLILIDGKPV-------SSRNSVrygwrgerdtrgDTN 139

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 141 SIPLAAIERIDILATGASAIYGADAVAGVINYILK---DDYQGAeVNTsYTNSFDSHDEGKKQ---LNL----------- 203
Cdd:PRK13524  140 WVPPEMIERIEVLRGPAAARYGNGAAGGVVNIITKkptGEWHGS-WNT-YFNAPEHKAEGATKrtnFSLsgplgdelsfr 217

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 204 VYGtNIGESNltvfADIYDRNAFKATDR--SYTATpnlvngysyLPklenspnvyyySSRDGNElpapncktelvtteyg 281
Cdd:PRK13524  218 LYG-NLNKTQ----ADAWDINQGHQSARtgSYAGT---------LP-----------AGREGVI---------------- 256

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 282 eeicayyaNQDdyletqfeslstgfmFNstlGDLDWHtdffysqtkskayssPAPINQINDDDGpYIIEDALFIYDNAD- 360
Cdd:PRK13524  257 --------NKD---------------IN---GLLRWD---------------FAPLQSLELEAG-YSRQGNLYAGDTQNt 294

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 361 GSNDLMDQLYIDPfTTQAGRDMYGFAFDARFNSPRT----VEVE-TKNFRLVSSLAGyigdwswesgitfsrskseqeAI 435
Cdd:PRK13524  295 NSDALVKSLYGKE-TNRMYRQNYALTHRGGWDNGVStsnyAQYEhTRNSRLPEGLAG---------------------GT 352

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 436 DGVYNryqfhaaitgELCSDGSMATYDGTQLNcaqgqlmpfynpflqgdanndavlelakanpsrsGEstvygWGLNFNg 515
Cdd:PRK13524  353 EGIFN----------EKATQFSTIDLDDVMLH----------------------------------SE-----VNLPFD- 382

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 516 dlFTFNELpiyAAFGIEARREELKDiPSLDSQARAENGYLVDVFGFGSSlSEADRTQYAAFVELNMPVTEQLELQVAGRY 595
Cdd:PRK13524  383 --LLVNQT---LTLGTEWNQQRMKD-PSSNTQALTSGGAIPGVSATGRS-PYSKAEIFSLFAEDNMELTDSTMLTPGLRF 455

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 596 DHYDDFGGTFNPKVGLSYRPSDSLIIRSSWSTSFRAPSLTQagvklrtTQSSFdcganqavaDLYCMGDGTEVRVNS--L 673
Cdd:PRK13524  456 DHHSIVGNNWSPSLNLSQGLGDDFTLKMGIARAYKAPNLYQ-------TNPNY---------ILYSKGQGCYASAGNgcY 519

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 674 ELGNQTLKAEESEALSIGFAWSPS-VNTNLTvdYWHFDHEQVIDTNMTAVLDRAITDASLRHCGLVP----QGQQGisye 748
Cdd:PRK13524  520 LQGNDDLKAETSVNKEIGLEFKRDgWLAGLT--WFRNDYRNKIEAGYVPVGTNSVGKTDIYQWENVPkavvEGLEG---- 593

                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 749 eqlceitdnaGLNIE-SDGANLSEILTNYISEFNPREDElflPLfrdHVIPlENTGTQTLagiDFKfdhrflfAQGNLTL 827
Cdd:PRK13524  594 ----------TLNVPvSETVNWTNNLTYMLQSKNKTTGD---PL---SIIP-EYTLNSTL---SWQ-------ATEDLSL 646

                         890       900       910       920       930       940       950       960
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 828 AFDGTHYlefERNKPgsdatekliGTYrypenvgrfsidwdaesyyinlgaNYTSSYEDDIEglrgreideleelgelnd 907
Cdd:PRK13524  647 QSTFTWY---GKQKP---------KKY------------------------NYKGQPVTGSA------------------ 672

                         970       980       990
                  ....*....|....*....|....*....|....*..
gi 2537525202 908 elKRDVDEWLVWDLSAGYFINDALSIRARIDNIFDKE 944
Cdd:PRK13524  673 --TKEVSPYSIVGLSATYDVTKNVSLTGGVDNLFDKR 707
PRK13528 PRK13528
outer membrane receptor FepA; Provisional
 107-975 1.85e-13

outer membrane receptor FepA; Provisional


Pssm-ID: 237413 [Multi-domain]  Cd Length: 727  Bit Score: 74.41  E-value: 1.85e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 107 LRGMGPSATLTLINGRRVApssfaagTENFV------------DVNSIPLAAIERIDILATGASAIYGADAVAGVINYIL 174
Cdd:PRK13528   99 IRGMGPENTLILIDGVPVT-------SRNSVryswrgerdtrgDTNWVPPEMVERIEVIRGPAAARYGSGAAGGVVNIIT 171

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 175 K---DDYQGAEvnTSYTNSFDSHDEG---KKQLNL------------VYGtNIGESNltvfADIYDRNAFKATdrSYTAT 236
Cdd:PRK13528  172 KrptNDWHGSL--SLYTNQPESSKEGatrRANFSLsgplagdaltmrLYG-NLNKTD----ADSWDINSSAGT--KNAAG 242

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 237 PNLV-----NG-YSYLPKLENSPNVYYYSSRDGNelpapncktelvtteygeeicaYYANqddylETQFeslSTGFMFNS 310
Cdd:PRK13528  243 REGVrnkdiNGvLSWKMTPQQILDFEAGYSRQGN----------------------IYAG-----DTQN---SNSSAVTE 292

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 311 TLGDLDWHTDFFYSQTKSKAYSSpapinqindddgpyiiedalfIYDnadgsndlmdqlyidpfttqAGRDMYGFAFDar 390
Cdd:PRK13528  293 SLAKSGKETNRLYRQNYGLTHNG---------------------IWD--------------------WGQSRLGFYYE-- 329

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 391 fnsprtvevETKNFRLVSSLAGYiGDWSWESGITFSRSKSEQEAIDGVYNryqfhaaitgelcsdgsmatydgtqlncaq 470
Cdd:PRK13528  330 ---------KTNNTRMNEGLAGG-GEGRITADQTFTTSRLESYRTSGELN------------------------------ 369

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 471 gqlMPFYNPFLQgdanndaVLELakanpsrsgestvygwglnfngdlftfnelpiyaafGIEARREELKDiPSLDSQARA 550
Cdd:PRK13528  370 ---VPLNWLFEQ-------TLTV------------------------------------GAEWNRDELND-PSSTSLTVK 402

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 551 eNGYLVDVFGFGSSLS-EADRTQYAAFVELNMPVTEQLELQVAGRYDHYDDFGGTFNPKVGLSYRPSDSLIIRSSWSTSF 629
Cdd:PRK13528  403 -DGDIGGISGSAADRSsKNKSEISALYVEDNIEPVPGTNLIPGLRFDYHSEFGSNWSPSLNLSQELGDYFKVKAGIARAF 481

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 630 RAPSLTQAGVKLRttqssfdcganqavadLYCMGDGTEVRVNS---LELGNQTLKAEESEALSIGFAWSPSvNTNLTVDY 706
Cdd:PRK13528  482 KAPNLYQSSEGYL----------------LYSRGNGCPKDITSggcYLVGNKNLDPEISVNKEIGLEFTVD-DYHASVTY 544

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 707 WHFDHEQVIDTnmtavldraitdaslrhcGLVPQGQQGisyeeqlceiTDNAGLNIESDGANLSEILtnyisefnprEDE 786
Cdd:PRK13528  545 FRNDYQNKIVA------------------GDDVIGRTA----------SGAYILQWQNGGKAVVEGL----------EGN 586

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 787 LFLPLFRDhviPLE-NTgtqtlagidfkfdhrflfaqgNLTlafdgthYLEFERNKpgsDATEKLIGTYRYPENVgrfSI 865
Cdd:PRK13528  587 LLVPLMKD---RLNwNT---------------------NAT-------YMITSEQK---DTGNPLSVIPKYTINS---TL 629

                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 866 DW---DAESYYINL-------GANYTSSYEDDIEGLRGREideleelgelndelkrdVDEWLVWDLSAGYFINDALSIRA 935
Cdd:PRK13528  630 DWqitQALSANVNWtlygkqkPRTHAESRSEETGGLSGKE-----------------LGAYSLVGVNVNYDINKNLRLNV 692

                         890       900       910       920
                  ....*....|....*....|....*....|....*....|
gi 2537525202 936 RIDNIFDKEppkLYGSSRGFDSinHNAYGSRYTLSLSYRF 975
Cdd:PRK13528  693 GVSNLFDKQ---IYREGEGANT--YNEPGRAYYAGVTASF 727
btuB PRK10641
TonB-dependent vitamin B12 receptor BtuB;
52-244 2.45e-12

TonB-dependent vitamin B12 receptor BtuB;


Pssm-ID: 236730 [Multi-domain]  Cd Length: 614  Bit Score: 70.79  E-value: 2.45e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202  52 PLTVLDQDAIKRSGANTIHELLKDLSvfkggsgTFSTSESGGtststpAGQSAaSL--RGMGPSATLTLINGRRVApssf 129
Cdd:PRK10641   45 PTTVVTRDDIDRWQSKSVNDVLRRLP-------GVDIAQNGG------LGQLS-SLfiRGTNSSHVLVLIDGVRLN---- 106

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 130 AAGTENFVDVNSIPLAAIERIDILATGASAIYGADAVAGVINYILKDDYQGAEVNTSY-TNSFDSHDEGKKQlnlvygtN 208
Cdd:PRK10641  107 QAGISGSADLSQIPISLVQRIEYIRGPRSAVYGSDAIGGVVNIITTRDKPGTTLSAGWgSNGYQNYDGSTQQ-------Q 179

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 2537525202 209 IGESNLTVFADIYdrnafkATDRSYTATPNLVNGYS 244
Cdd:PRK10641  180 LGDNTRVTLAGDY------TYTKGFDVVAYGNTGTQ 209
PRK13483 PRK13483
ligand-gated channel protein;
527-710 1.04e-11

ligand-gated channel protein;


Pssm-ID: 184080 [Multi-domain]  Cd Length: 660  Bit Score: 69.03  E-value: 1.04e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 527 AAFGIEARREELKDIPSldSQAraengylvdvfgfgSSLSEADRTQYAAFVELNMPVTEQLELQVAGRYDHYDDFGGTFN 606
Cdd:PRK13483  342 LTFGAAYNHQDLTDETS--NQI--------------SDLTDISRTQWAVFSEDEWRIADDFALTGGLRLDHDENFGGHVS 405

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 607 PKVGLSYRPSDSLIIRSSWSTSFRAPSLTQagvklrTTQssfDCGANQAVADLYcmgdgtevrvnslelGNQTLKAEES- 685
Cdd:PRK13483  406 PRVYGVWNLAPSWTVKGGVSTGFRAPSLRQ------TTP---DWGQVSRGGNIY---------------GNPDLKPETSl 461

                         170       180
                  ....*....|....*....|....*.
gi 2537525202 686 -EALSIGFAWSPSVNTNLTVDYWHFD 710
Cdd:PRK13483  462 nKELGLYYDLGSGLTASLTVFYNEFK 487
PRK13483 PRK13483
ligand-gated channel protein;
1-177 1.11e-11

ligand-gated channel protein;


Pssm-ID: 184080 [Multi-domain]  Cd Length: 660  Bit Score: 68.65  E-value: 1.11e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202   1 MFRQLTIAVAISAVLCPVQSVYAQ-NDQQSEKIERVEVTGSRIKGVDLEGTIPLTVLDQDAIKRSGANTIHELLKDLSvf 79
Cdd:PRK13483    1 MKKYLAQVISALCLLPAVFVTHALaQAAPDKTMETVVVTASGYEQQIRDAPASISVITREDLENRFYRDLTDALLDVP-- 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202  80 kggsGTFSTSesGGTSTSTpagqsaaSLRGMGPSATLTLINGRRVA-----PSSFAAGTENfvdVNSIPLAAIERIDILA 154
Cdd:PRK13483   79 ----GVVVTG--GGDRTDI-------SLRGMGSQYTLILVDGKRQSsretrPNSDGPGVEQ---AWTPPLAAIERIEVIR 142

                         170       180
                  ....*....|....*....|...
gi 2537525202 155 TGASAIYGADAVAGVINYILKDD 177
Cdd:PRK13483  143 GPMSSLYGSDAIGGVINIITRKV 165
PRK13486 PRK13486
TonB-dependent receptor;
11-175 2.98e-11

TonB-dependent receptor;


Pssm-ID: 139606 [Multi-domain]  Cd Length: 696  Bit Score: 67.35  E-value: 2.98e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202  11 ISAVLCPVQSVYAQNDQQSEKIERVEVTGSRIKGVDLEGTIplTVLDQDAIKrsgANTIHELLKDLSVFKGGSGTFSTSE 90
Cdd:PRK13486    6 LASVVIPCLGFSASSIAAAEDVMIVSASGYEKKLTNAAASV--SVISQEELQ---SSQYHDLAEALRSVEGVDVESGTGK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202  91 SGGTSTStpagqsaasLRGMGPSATLTLINGRR------VAPSSFAAGTENFVDvnsiPLAAIERIDILATGASAIYGAD 164
Cdd:PRK13486   81 TGGLEIS---------IRGMPASYTLILIDGVRqggssdVTPNGFSAMNTGFMP----PLAAIERIEVIRGPMSTLYGSD 147

                         170
                  ....*....|.
gi 2537525202 165 AVAGVINYILK 175
Cdd:PRK13486  148 AMGGVVNIITR 158
PRK13513 PRK13513
ligand-gated channel protein;
5-175 8.95e-11

ligand-gated channel protein;


Pssm-ID: 184104 [Multi-domain]  Cd Length: 659  Bit Score: 65.94  E-value: 8.95e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202   5 LTIAVAISA-VLCPVQSVYAQNDqqseKIERVEVTGSRIKGVDLEGTIplTVLDQDAIKRSGANTIHELLKDLSvfkggs 83
Cdd:PRK13513   13 LVIAAAISSqAYAAEKTNTATPT----DTMVVTASGFQQRIQDAPASI--SVVTREQLENKAYRDVTDALKDVP------ 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202  84 GTFSTsesGGTSTSTpagqsaASLRGMGPSATLTLINGRRVA-----PSSFAAGTENFVdvnSIPLAAIERIDILATGAS 158
Cdd:PRK13513   81 GVVVT---GGGSTSD------ISIRGMAAKYTLILVDGKRVDtrstrPNSDGSGIEQGW---LPPLAAIERIEVVRGPMS 148

                         170
                  ....*....|....*..
gi 2537525202 159 AIYGADAVAGVINYILK 175
Cdd:PRK13513  149 SLYGSDAMGGVINIITR 165
PRK13484 PRK13484
IreA family TonB-dependent siderophore receptor;
1-175 2.40e-09

IreA family TonB-dependent siderophore receptor;


Pssm-ID: 139605 [Multi-domain]  Cd Length: 682  Bit Score: 61.18  E-value: 2.40e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202   1 MFRQLTIAVAISAVL-CPVQSVYAQNDqqsEKIERVEVTGSRIKGVDLEGTIPLTVLDQDAIKRSGANTIHELLKDLSvf 79
Cdd:PRK13484    1 MKNKYIIAPGIAVMCsAVISSGYASSD---KKEDTLVVTASGFTQQLRNAPASVSVITSEQLQKKPVSDLVDAVKDVE-- 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202  80 kggsgtfstsesgGTSTSTPAGQSAASLRGMGPSATLTLINGRRVAP-SSFAAGTENFVDVNSIPLAAIERIDILATGAS 158
Cdd:PRK13484   76 -------------GISITGGNEKPDISIRGLSGDYTLILVDGRRQSGrESRPNGSGGFEAGFIPPVEAIERIEVIRGPMS 142

                         170
                  ....*....|....*..
gi 2537525202 159 AIYGADAVAGVINYILK 175
Cdd:PRK13484  143 SLYGSDAIGGVINIITK 159
Fiu COG4774
Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism];
54-975 6.34e-08

Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism];


Pssm-ID: 443806 [Multi-domain]  Cd Length: 639  Bit Score: 56.42  E-value: 6.34e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202  54 TVLDQDAIKRSGANTIHELLK-DLSVfkggsgTFSTSESGGtststpagQSAASLRGMGPSATlTLINGRRVAPSsfaag 132
Cdd:COG4774    14 TVVTRELIEDQGATSLADALRnVPGV------TFGAGEGGN--------GDSFSIRGFSASGD-IYVDGLRDPGQ----- 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 133 tenfvdvNSIPLAAIERIDILATGASAIYGADAVAGVINYILK--DDYQGAEVNTSYtNSFDShdegkKQLNLVYGTNIG 210
Cdd:COG4774    74 -------YRRDTFNLERVEVLKGPASVLYGRGSPGGVINLVTKrpTDEPFTEVTLTY-GSDGQ-----RRATLDVNGPLG 140

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 211 ESnltvfadiydrNAFkatdRsytatpnlVNGysylpklenspnvyyySSRDGNelpapncktelvtteygeeicAYYAN 290
Cdd:COG4774   141 DD-----------LAY----R--------LNG----------------MYRDSD---------------------SYRDG 160

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 291 QDDylETQFESLSTGFMFNStlgDLDWHTDFFYSQTKSKAYSS-PApinqinDDDGPYIIEDALFIYDNADGSNDLMDql 369
Cdd:COG4774   161 VDN--DRWGIAPSLTWRLGD---RTRLTLDYEYQDDDRTPDYGvPA------VANGRPVDVDRSTFYGQPDDYSDSET-- 227

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 370 yidpfttqagrDMYGFAFDARFNSprtvevetknfrlvsslagyigDWSWESGITFSRskseqeaidgvYNRYQFHAAIT 449
Cdd:COG4774   228 -----------DSATLRLEHDFND----------------------NWTLRNALRYSD-----------YDRDYRNTYPT 263

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 450 GelcsdgsmatydgtqlncaqgqlmpfynpflqGDANNDavleLAKANPSRSGESTVYGWGLNFNGDLFTF---NELpiy 526
Cdd:COG4774   264 G--------------------------------GNATGT----VTRSAYRRDQDNDTLSNQTDLTGKFDTGgvkHTL--- 304

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 527 aAFGIEARREELKDIPSLDSQARA-------ENGYLVDVFGFGSSLSEADRTQYAAFVELNMPVTEQLELQVAGRYDHYD 599
Cdd:COG4774   305 -LAGVEYSREDSDNARYSGGGTAPtvnlynpVYGAPVTGPTLGGADNDSRTDTTGLYLQDTISLTDRWSLLAGLRYDRFD 383

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 600 ------DFGGT--------FNPKVGLSYRPSDSLIIRSSWSTSFRAPSltqagvklrttqssfdcGANQAVADlycmgdg 665
Cdd:COG4774   384 tdytdrTTGATtssyddsaFSPRAGLVYKPTPNLSLYASYSTSFNPGG-----------------GAPSLSNA------- 439

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 666 tevrvnslelgNQTLKAEESEALSIGFAWSPsvntnltvdywhFDheqvidtnmtavlDRAITDASLrhcglvpqgqqgi 745
Cdd:COG4774   440 -----------GQALDPEKSRQYEVGVKWDL------------LD-------------GRLSLTAAL------------- 470

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 746 sYeeqlceitdnaglniesdganlseiltnYISEFNPREDELFLPLFrdhvipLENTGTQTLAGIDfkfdhrfLFAQGNL 825
Cdd:COG4774   471 -F----------------------------RIEKTNVRTTDPANPGV------YVQTGEQRSRGVE-------LEATGEL 508

                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 826 T--LAFDGTH-YLEFERNKPGSDATE--KLIGTyryPENVGRFSIDWD--AESYYINLGANYTSS-YEDDIEGLRgreid 897
Cdd:COG4774   509 TpgWSVLAGYtYLDAEITKSANAANVgnRLPNV---PRHSASLWTTYDlpLPGLTLGGGVRYVGSrYADAANTVK----- 580

                         890       900       910       920       930       940       950       960
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 898 eleelgelndelkrdVDEWLVWDLSAGYFINDALSIRARIDNIFDKeppKLYGSSRGFdsiNHNAYGS--RYTLSLSYRF 975
Cdd:COG4774   581 ---------------LPSYTRFDAGASYRLNKNLTLRLNVNNLTDK---RYYASAYGS---GYVTPGAprTVLLSASYRF 639
FhuE COG4773
Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion ...
 499-975 2.62e-06

Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion transport and metabolism];


Pssm-ID: 443805 [Multi-domain]  Cd Length: 692  Bit Score: 51.43  E-value: 2.62e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 499 SRSGESTVYGWGLNFNGDLFTF---NELpiyaAFGIEARREELK----DIPSLDsqARAENGYLVDVFGFGSSLSEADRT 571
Cdd:COG4773   337 ARDGDSRSDSLDANLNGKFETGgleHTL----LVGADYSRYDSDsdsaTAGTIN--IYNPVYGNLPEPDFDASDTDTTTR 410

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 572 QYAAFVELNMPVTEQLELQVAGRYDHYDDFGGT-------------FNPKVGLSYRPSDSLIIRSSWSTSFRapsltqag 638
Cdd:COG4773   411 QTGLYAQDQISLTDRLSLLLGGRYDWYETDSTNrlggsttsyddsaFTPRAGLVYDLTPGLSLYASYSESFE-------- 482

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 639 vklrttqssfdcgaNQAVADLYcmgdgtevrvnslelgNQTLKAEESEALSIGFAWSP---SVNTNLTVdywhFDheqvI 715
Cdd:COG4773   483 --------------PQSGADNN----------------GNPLDPETGKQYEAGVKGELfdgRLNATLAV----FD----I 524

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 716 DTNMTAVLDRAITDASlrhcglVPQGQQgisyeeqlceitdnaglniESDGAnlseiltnyisEFNpredelflplfrdh 795
Cdd:COG4773   525 TQKNVATTDPDNPNFY------VQVGEV-------------------RSRGV-----------ELE-------------- 554

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 796 viplentgtqtlagidfkfdhrflfAQGNLT--------LAFDGTHYLEFERNKPGSDATekligtyRYPENVGRFSIDW 867
Cdd:COG4773   555 -------------------------LSGELTpglnliagYTYTDAKITKDADALEGKRLT-------NVPRHTASLWTTY 602

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 868 DAESYY-----INLGANYTSSYEDDIEGlrgreideleelgelndelKRDVDEWLVWDLSAGYFINDALSIRARIDNIFD 942
Cdd:COG4773   603 RFPSGAlkglgLGGGVRYVGERYGDAAN-------------------TFTLPSYTLVDAGARYDLGKNWTLQLNVNNLFD 663

                         490       500       510
                  ....*....|....*....|....*....|....*
gi 2537525202 943 KeppKLYGSSRGFDSINhnaYGSR--YTLSLSYRF 975
Cdd:COG4773   664 K---KYYASSGSRGYVY---YGAPrnVRLSLSYKF 692
FhuE COG4773
Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion ...
 18-194 4.33e-06

Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion transport and metabolism];


Pssm-ID: 443805 [Multi-domain]  Cd Length: 692  Bit Score: 50.66  E-value: 4.33e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202  18 VQSVYAQNDQQSEKIERVEVTGSRIKGVDLE---------GTIPL-------TVLDQDAIKRSGANTIHELLKDLSvfkg 81
Cdd:COG4773    18 LAQAAAAAAAEATTLPEVTVTGTAEGTGGYTakssstatkLDTPLretpqsvSVVTRQLIEDQGATTLDDALRNVP---- 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202  82 gsGTFSTSESGGtststpaGQSAASLRGMgpSATLTLINGRRVAPSSFAagtenfvdvnSIPLAAIERIDILATGASAIY 161
Cdd:COG4773    94 --GVTVSSYDGG-------GRDSFSIRGF--SIDNYLRDGLPLGGFGGG----------QPDTANLERVEVLKGPAGLLY 152

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 2537525202 162 GADAVAGVINYILK--DDYQGAEVNTSYtNSFDSH 194
Cdd:COG4773   153 GAGSPGGLVNLVTKrpTAEPQGEVSLSA-GSWDTY 186
TonB-siderophor TIGR01783
TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of ...
 54-176 5.22e-06

TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of TonB-dependent outer membrane siderophore receptors. It has no overlap with TonB receptors known to transport other substances, but is likely incomplete due to lack of characterizations. It is likely that genuine siderophore receptors will be identified which score below the noise cutoff to this model at which point the model should be updated. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273805 [Multi-domain]  Cd Length: 651  Bit Score: 50.49  E-value: 5.22e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202  54 TVLDQDAIKRSGANTIHELLKDLSvfkggSGTFSTSESGGTStstpagqSAASLRGMGPSATL--TLINGRR-VAPSSFA 130
Cdd:TIGR01783   7 SVITRQELEDQQAGSLSEALQRVP-----GVVVGGSGGTTQF-------GNITIRGFGLEVDIdnVYLDGVPlLSRGNLA 74

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 2537525202 131 agtenfvdvnSIPLAAIERIDILATGASAIYGADAVAGVINYILKD 176
Cdd:TIGR01783  75 ----------IVDPAMVERVEVLRGPASLLYGGSAPGGVINIVTKR 110
btuB PRK10641
TonB-dependent vitamin B12 receptor BtuB;
918-975 5.73e-05

TonB-dependent vitamin B12 receptor BtuB;


Pssm-ID: 236730 [Multi-domain]  Cd Length: 614  Bit Score: 46.91  E-value: 5.73e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2537525202 918 VWDLSAGYFINDALSIRARIDNIFDKEPPKLYGssrgfdsinHNAYGSRYTLSLSYRF 975
Cdd:PRK10641  566 LWDLAVSYPVTSHLTVRGKIANLFDKDYETVYG---------YQTAGREYTLSGSYTF 614
PRK13484 PRK13484
IreA family TonB-dependent siderophore receptor;
572-695 6.10e-05

IreA family TonB-dependent siderophore receptor;


Pssm-ID: 139605 [Multi-domain]  Cd Length: 682  Bit Score: 46.92  E-value: 6.10e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 572 QYAAFVELNMPVTEQLELQVAGRYDHYDDFGGTFNPKVGLSYRPSDSLIIRSSWSTSFRAPSltqagvkLRTTQSSFDCG 651
Cdd:PRK13484  384 QKAVFIENEYAATDSLALTGGLRLDNHEIYGSYWNPRLYAVYNLTDNLTLKGGIAKAFRAPS-------IREVSPGFGTL 456

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 2537525202 652 ANQAVADLYcmgdgtevrvnslelGNQTLKAEESEALSIGFAWS 695
Cdd:PRK13484  457 TQGGASIMY---------------GNRDLKPETSVTEEIGIIYS 485
TonB-Xanth-Caul TIGR01782
TonB-dependent receptor; This model represents a family of TonB-dependent outer-membrane ...
 93-975 6.29e-05

TonB-dependent receptor; This model represents a family of TonB-dependent outer-membrane receptors which are found mainly in Xanthomonas and Caulobacter. These appear to represent the expansion of a paralogous family in that the 22 X. axonopodis (21 in X. campestris) and 18 C. crescentus sequences are more closely related to each other than any of the many TonB-dependent receptors found in other species. In fact, the Crescentus and Xanthomonas sequences are inseparable on a phylogenetic tree using a PAM-weighted neighbor-joining method, indicating that one of the two genuses may have acquired this set of receptors from the other. The mechanism by which this family is shared between Xanthomonas, a gamma proteobacterial plant pathogen and Caulobacter, an alpha proteobacterial aquatic organism is unclear. [Transport and binding proteins, Porins]


Pssm-ID: 273804 [Multi-domain]  Cd Length: 845  Bit Score: 46.94  E-value: 6.29e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202  93 GTSTSTPAGQ-SAASLRGMGPSATLTLINGRRVA--------------PSSFAAGtenfVDVNSIPLAAIER------ID 151
Cdd:TIGR01782  52 GVSIERDQGEgRYVSVRGLGPSYNRTTLNGRTIAstdsggrafsldllPSELVSG----VEVYKTPTADMDEggiggtVD 127

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 152 I------------LATGASAIYGADA--------VAGVINYILKDDYQGAEVNTSYTNSFDSHDEGKKQLNLVYGTNIGE 211
Cdd:TIGR01782 128 LrtrspfdydgrtLSGSAQGGYNDLAgkdkpgprGAASYSWTFGDGQFGVLLSASYQKRDFAEDNVETENWGTYTSADGG 207

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 212 SNLTVFADIYdRNAFKATDRS-YTATPNL---------VNGYSYLPKLENSPNVYYYSSRDGNELPAPNCKTELVTT--- 278
Cdd:TIGR01782 208 AQGLYFPRGV-RYRSYRNDRErKGVNGSLqwrpsdaleLYLDTLYSKYDDDETRQQIEFRTLNGGSTVITSNQTATSgal 286

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 279 EYGEEICAYYANQDDYLET--QFESLSTGFMFNSTLGDLDWhtDFFYSQTK-------SKAYSSPAPInqindDDGPYII 349
Cdd:TIGR01782 287 VQGTVANLQILVEARYNEEkeTTTSLTLGGEWTGDRWTLDG--DLGYSKATrdrpdrvTRFFTAPTPG-----YDFDYRG 359

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 350 EDALFIYDNADGSNDL---------MDQLYIDPftTQAGRDMYGFAFDARFNSPRT-VEVETKNFRLVSSLAGYIGDWSW 419
Cdd:TIGR01782 360 GPTLTLGTPADGDDASnytnpangeLRRTQISY--QKAEDSEDAAQLDATFDGPFTsLKFGVRYRRRDKTNRGSRYRRSI 437

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 420 ESGITFSrskseqeaidGVYNRYQFHAAITGELCSDGSMATYDGTQLNCAQGQLMPFYNPFLQGDANNDAvlelakANPS 499
Cdd:TIGR01782 438 IGATGAS----------GLAGVPSDLAGAGLDGGLGGPLTGWDPADLDAFLNAARGDAAGGGTYTYASTA------PNTY 501

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 500 RSGESTVYGWG-LNFNGDlftfneLPIYAAFGIearREELKDIPSLDSQARAENGYLVDVFGFgsslSEADRTqyaafve 578
Cdd:TIGR01782 502 TVTEDTTAAYAmANFDTG------LRLRGNVGV---RYERTDQTSDGWQSQPAANGTGSVLVP----VSADRD------- 561

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 579 lnmpvteqlelqvagrydhYDDFGGTFNpkvgLSYRPSDSLIIRSSWSTSFRAPSLTQagvkLRTTQSSFDCGANQAVAd 658
Cdd:TIGR01782 562 -------------------YTDVLPSLN----LAYDLTDDLVLRFAASKTITRPDFGD----LAANTSLSDDGTGGTVT- 613

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 659 lycmgdgtevrvnsLELGNQTLKAEESEALSIGFAWSPSVNTNLTVDYWHFDHEQVIdTNMTAVLDRAITDASLRHCGLV 738
Cdd:TIGR01782 614 --------------VSGGNPDLKPYESDNLDLSLEWYFGPGGLLSAAVFYKDIKNFI-VTTTSTETNDGGGGLVVAGVLV 678

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 739 PQGQqgisyeeqlceitdNAGLNIESDGANLseiltNYISEFNpredelFLPlfrdhvIPLENTGTQTlagidfkfdhrf 818
Cdd:TIGR01782 679 SRPV--------------NGGKAGKIRGVEL-----GYQQTFD------FLP------GPLSGFGVQA------------ 715

                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202 819 lfaqgNLTlafdgthYLEFERNKPGSDATEKLIGTYRYPENVGRFSIDWDAESYYINLGANYTSSYEDDIEGLRgreide 898
Cdd:TIGR01782 716 -----NYT-------YVDSEADPSVDGVQRRKLPLPGLSKNTANATLYYEKGGFSARLSYNYRSDYLLDVGGSN------ 777

                         890       900       910       920       930       940       950
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2537525202 899 leelgelNDELKRDVDEWLVWDLSAGYFINDALSIRARIDNIFDkEPPKLYGSSRGFdSINHNAYGSRYTLSLSYRF 975
Cdd:TIGR01782 778 -------INRLDRYVDPRGQLDLSASYQVSDHLSLGLQASNLTN-EPSRWYTGGKQR-PREYVETGRTYMLGLRYKF 845
PRK09840 PRK09840
catecholate siderophore receptor Fiu; Provisional
 2-175 4.03e-04

catecholate siderophore receptor Fiu; Provisional


Pssm-ID: 182105 [Multi-domain]  Cd Length: 761  Bit Score: 44.41  E-value: 4.03e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202   2 FRQLTIAVAISAVLCPVQSVYAQNDQ-QSEKIERVEVTG-SRIKG------------VDLEGTIplTVLDQDAIKRSGAN 67
Cdd:PRK09840   12 FHSLAFFAGLCIGITPVAQALAAEGQtNADDTLVVEASTpSLYAPdqsadpkfsqplADTTQTI--TVISEQVIKDQGAT 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537525202  68 TIHELLKDLSvfkgGSGTFSTSESGGTSTStpagqSAASLRGMGPSATLtLINGRRvapssfaagtenfvDVNSIP--LA 145
Cdd:PRK09840   90 NLTEALRNVP----GVGTFFAGENGNTTTG-----DAIYMRGFDTSNSI-YVDGIR--------------DIGSISrdTF 145

                         170       180       190
                  ....*....|....*....|....*....|
gi 2537525202 146 AIERIDILATGASAIYGADAVAGVINYILK 175
Cdd:PRK09840  146 NTEQVEVIKGPSGTDYGRSAPTGSINMISK 175
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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