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Conserved domains on  [gi|2537605254|ref|WP_294123142|]
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SurA N-terminal domain-containing protein [Pseudoalteromonas sp.]

Protein Classification

peptidyl-prolyl isomerase family protein( domain architecture ID 1001049)

peptidylprolyl isomerase (PPIase) accelerates the folding of proteins; it catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; may be partial

EC:  5.2.1.8
Gene Ontology:  GO:0003755
PubMed:  19866485

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
PRK10788 super family cl32577
periplasmic folding chaperone; Provisional
 1-620 3.93e-151

periplasmic folding chaperone; Provisional


The actual alignment was detected with superfamily member PRK10788:

Pssm-ID: 182731 [Multi-domain]  Cd Length: 623  Bit Score: 450.23  E-value: 3.93e-151
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537605254   1 MLEKIREGSQGPVAKIILGAVILSFALAGIGSYLGQTTEQPVAEVNGIKISQTDFNRAYQNERSRLEQQFGEYFTQIAAD 80
Cdd:PRK10788    1 MMDNLRTAANSVVLKIILALIILSFILTGVGGYLIGGSNNYAAKVNGQEISRAQLEQAFQSERNRLQQQLGDQFSELAAN 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537605254  81 PNYMAQIRQGVVDRLVQQELQSQLAADLGLRVSDESVRKTILELPYFQIGEKFNNDRYLQVIRQMNFQPDAFREYLRKDM 160
Cdd:PRK10788   81 EGYMKQLRQQVLNRLIDEALLDQYARELGLGISDEQVKQAIFATPAFQTDGKFDNNKYLAILNQMGMTADQYAQALRQQL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537605254 161 TRSQVVSAIAGTDFALESELKSAIALQQQTRSIDYLVINKEALAANVEVSDQEVSDYYDLNASQFLSPELISVSYIELKA 240
Cdd:PRK10788  161 TTQQLINGVAGTDFMLPGETDELAALVAQQRVVREATIDVNALAAKQTVTDEEIKSYYDQNKNNFMAPEQFKVSYIKLDA 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537605254 241 AGI-NVESVTEDDVKAYYEQNKAQYVEPEKRRVSHILIdNSEDDdaakekANALHAQLEQGADFAELAQSSSDDIVSGEM 319
Cdd:PRK10788  241 ATMqQKITVSDADIQAYYDQHQDQFTQPERKRYSIIQT-KTEAE------AKAVLDELKKGADFATLAKEKSTDIISARN 313

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537605254 320 GGDLEWIERDVMDPAFEDAtfALQNKGDISEVVASEFGYHIIKLTDIQPQQVKAYDDVKADLRAELEQAEKVDAFYEKQT 399
Cdd:PRK10788  314 GGDLGWLEPATTPDELKNA--GLKEKGQLSGVIKSSVGFLIVRLDDIQPAKVKPLSEVRDDIAAKVKQEKALDAYYALQQ 391

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537605254 400 EMGALAFEISDRLDDAAEVAEVEVKSTPLLALNALPEPLNSPAVVTALTSVDLLEDK----VNSEVIELGEEHAIIVRIN 475
Cdd:PRK10788  392 KVSDAASNDNESLASAEQAAGVKAVQTGWFSRDNVPAELNFKPVAQAIFNGGLVGENgapgSNSDVITVDGDRAFVLRIS 471

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537605254 476 EHKAAATKPLDEVSEQIKARLVNEKSSELAKEKARSLFAEVQAGKSlNDVASEQSLTVRQEAQLTRQSYTvsPAIVTQAF 555
Cdd:PRK10788  472 EHKPEAVKPLAQVRDQVTELVKRQKAEQQAKVDAEKLLAALKAGKG-EEAMKAAGLSFGEPKTLSRTSQD--DPLSQAAF 548

                         570       580       590       600       610       620
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2537605254 556 KMAHPA-DSAIVELVNLNNGDAAIVALKSVTDAQVAaniDPQAKQSITMAQANKNYMVFiEALKAN 620
Cdd:PRK10788  549 ALPLPAkDKPSYGMAQDMQGNVVLIALDEVTPGSMP---EEQKKAMVQGITQNNAQIAF-EALMSN 610
 
Name Accession Description Interval E-value
PRK10788 PRK10788
periplasmic folding chaperone; Provisional
 1-620 3.93e-151

periplasmic folding chaperone; Provisional


Pssm-ID: 182731 [Multi-domain]  Cd Length: 623  Bit Score: 450.23  E-value: 3.93e-151
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537605254   1 MLEKIREGSQGPVAKIILGAVILSFALAGIGSYLGQTTEQPVAEVNGIKISQTDFNRAYQNERSRLEQQFGEYFTQIAAD 80
Cdd:PRK10788    1 MMDNLRTAANSVVLKIILALIILSFILTGVGGYLIGGSNNYAAKVNGQEISRAQLEQAFQSERNRLQQQLGDQFSELAAN 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537605254  81 PNYMAQIRQGVVDRLVQQELQSQLAADLGLRVSDESVRKTILELPYFQIGEKFNNDRYLQVIRQMNFQPDAFREYLRKDM 160
Cdd:PRK10788   81 EGYMKQLRQQVLNRLIDEALLDQYARELGLGISDEQVKQAIFATPAFQTDGKFDNNKYLAILNQMGMTADQYAQALRQQL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537605254 161 TRSQVVSAIAGTDFALESELKSAIALQQQTRSIDYLVINKEALAANVEVSDQEVSDYYDLNASQFLSPELISVSYIELKA 240
Cdd:PRK10788  161 TTQQLINGVAGTDFMLPGETDELAALVAQQRVVREATIDVNALAAKQTVTDEEIKSYYDQNKNNFMAPEQFKVSYIKLDA 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537605254 241 AGI-NVESVTEDDVKAYYEQNKAQYVEPEKRRVSHILIdNSEDDdaakekANALHAQLEQGADFAELAQSSSDDIVSGEM 319
Cdd:PRK10788  241 ATMqQKITVSDADIQAYYDQHQDQFTQPERKRYSIIQT-KTEAE------AKAVLDELKKGADFATLAKEKSTDIISARN 313

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537605254 320 GGDLEWIERDVMDPAFEDAtfALQNKGDISEVVASEFGYHIIKLTDIQPQQVKAYDDVKADLRAELEQAEKVDAFYEKQT 399
Cdd:PRK10788  314 GGDLGWLEPATTPDELKNA--GLKEKGQLSGVIKSSVGFLIVRLDDIQPAKVKPLSEVRDDIAAKVKQEKALDAYYALQQ 391

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537605254 400 EMGALAFEISDRLDDAAEVAEVEVKSTPLLALNALPEPLNSPAVVTALTSVDLLEDK----VNSEVIELGEEHAIIVRIN 475
Cdd:PRK10788  392 KVSDAASNDNESLASAEQAAGVKAVQTGWFSRDNVPAELNFKPVAQAIFNGGLVGENgapgSNSDVITVDGDRAFVLRIS 471

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537605254 476 EHKAAATKPLDEVSEQIKARLVNEKSSELAKEKARSLFAEVQAGKSlNDVASEQSLTVRQEAQLTRQSYTvsPAIVTQAF 555
Cdd:PRK10788  472 EHKPEAVKPLAQVRDQVTELVKRQKAEQQAKVDAEKLLAALKAGKG-EEAMKAAGLSFGEPKTLSRTSQD--DPLSQAAF 548

                         570       580       590       600       610       620
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2537605254 556 KMAHPA-DSAIVELVNLNNGDAAIVALKSVTDAQVAaniDPQAKQSITMAQANKNYMVFiEALKAN 620
Cdd:PRK10788  549 ALPLPAkDKPSYGMAQDMQGNVVLIALDEVTPGSMP---EEQKKAMVQGITQNNAQIAF-EALMSN 610
SurA_N_3 pfam13624
SurA N-terminal domain; This domain is found at the N-terminus of the chaperone SurA. It is a ...
 1-166 1.23e-53

SurA N-terminal domain; This domain is found at the N-terminus of the chaperone SurA. It is a helical domain of unknown function. The C-terminus of the SurA protein folds back and forms part of this domain also but is not included in the current alignment.


Pssm-ID: 433358 [Multi-domain]  Cd Length: 162  Bit Score: 180.46  E-value: 1.23e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537605254   1 MLEKIREGSQGPVAKIILGAVILSFALAGIGSYLGQTTEqPVAEVNGIKISQTDFNRAYQNERSRLEQQFGEYFTQIAAD 80
Cdd:pfam13624   1 MLEFIRKHAKSWIAKIILGLIILSFVFWGVGSYFSGGGG-AVAKVNGEKISRAEFQRAYRRQLDQLRQQFGPNLDAELLD 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537605254  81 PnymAQIRQGVVDRLVQQELQSQLAADLGLRVSDESVRKTILELPYFQIGEKFNNDRYLQVIRQMNFQPDAFREYLRKDM 160
Cdd:pfam13624  80 E---LGLRQQVLDQLIDRALLLQEAKKLGLAVSDEEVRQAIASIPAFQEDGKFDKERYRQLLRANGLTPAEFEASLRQDL 156


                  ....*.
gi 2537605254 161 TRSQVV 166
Cdd:pfam13624 157 LLQQLL 162
SurA COG0760
Peptidyl-prolyl isomerase, parvulin family [Posttranslational modification, protein turnover, ...
 262-397 1.92e-39

Peptidyl-prolyl isomerase, parvulin family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440523 [Multi-domain]  Cd Length: 143  Bit Score: 141.64  E-value: 1.92e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537605254 262 AQYVEPEKRRVSHILI--DNSEDDDAAKEKANALHAQLEQGADFAELAQSSSDDIVSGEMGGDLEWIERDVMDPAFEDAT 339
Cdd:COG0760     1 DQFDSPEEVRASHILVkvPPSEDRAKAEAKAEELLAQLKAGADFAELAKEYSQDPGSAANGGDLGWFSRGQLVPEFEEAA 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2537605254 340 FALQnKGDISEVVASEFGYHIIKLTDIQPQQVKAYDDVKADLRAELEQaEKVDAFYEK 397
Cdd:COG0760    81 FALK-PGEISGPVKTQFGYHIIKVEDRRPAETPPFEEVKQQIRQELFQ-QALEAWLEE 136
 
Name Accession Description Interval E-value
PRK10788 PRK10788
periplasmic folding chaperone; Provisional
 1-620 3.93e-151

periplasmic folding chaperone; Provisional


Pssm-ID: 182731 [Multi-domain]  Cd Length: 623  Bit Score: 450.23  E-value: 3.93e-151
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537605254   1 MLEKIREGSQGPVAKIILGAVILSFALAGIGSYLGQTTEQPVAEVNGIKISQTDFNRAYQNERSRLEQQFGEYFTQIAAD 80
Cdd:PRK10788    1 MMDNLRTAANSVVLKIILALIILSFILTGVGGYLIGGSNNYAAKVNGQEISRAQLEQAFQSERNRLQQQLGDQFSELAAN 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537605254  81 PNYMAQIRQGVVDRLVQQELQSQLAADLGLRVSDESVRKTILELPYFQIGEKFNNDRYLQVIRQMNFQPDAFREYLRKDM 160
Cdd:PRK10788   81 EGYMKQLRQQVLNRLIDEALLDQYARELGLGISDEQVKQAIFATPAFQTDGKFDNNKYLAILNQMGMTADQYAQALRQQL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537605254 161 TRSQVVSAIAGTDFALESELKSAIALQQQTRSIDYLVINKEALAANVEVSDQEVSDYYDLNASQFLSPELISVSYIELKA 240
Cdd:PRK10788  161 TTQQLINGVAGTDFMLPGETDELAALVAQQRVVREATIDVNALAAKQTVTDEEIKSYYDQNKNNFMAPEQFKVSYIKLDA 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537605254 241 AGI-NVESVTEDDVKAYYEQNKAQYVEPEKRRVSHILIdNSEDDdaakekANALHAQLEQGADFAELAQSSSDDIVSGEM 319
Cdd:PRK10788  241 ATMqQKITVSDADIQAYYDQHQDQFTQPERKRYSIIQT-KTEAE------AKAVLDELKKGADFATLAKEKSTDIISARN 313

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537605254 320 GGDLEWIERDVMDPAFEDAtfALQNKGDISEVVASEFGYHIIKLTDIQPQQVKAYDDVKADLRAELEQAEKVDAFYEKQT 399
Cdd:PRK10788  314 GGDLGWLEPATTPDELKNA--GLKEKGQLSGVIKSSVGFLIVRLDDIQPAKVKPLSEVRDDIAAKVKQEKALDAYYALQQ 391

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537605254 400 EMGALAFEISDRLDDAAEVAEVEVKSTPLLALNALPEPLNSPAVVTALTSVDLLEDK----VNSEVIELGEEHAIIVRIN 475
Cdd:PRK10788  392 KVSDAASNDNESLASAEQAAGVKAVQTGWFSRDNVPAELNFKPVAQAIFNGGLVGENgapgSNSDVITVDGDRAFVLRIS 471

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537605254 476 EHKAAATKPLDEVSEQIKARLVNEKSSELAKEKARSLFAEVQAGKSlNDVASEQSLTVRQEAQLTRQSYTvsPAIVTQAF 555
Cdd:PRK10788  472 EHKPEAVKPLAQVRDQVTELVKRQKAEQQAKVDAEKLLAALKAGKG-EEAMKAAGLSFGEPKTLSRTSQD--DPLSQAAF 548

                         570       580       590       600       610       620
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2537605254 556 KMAHPA-DSAIVELVNLNNGDAAIVALKSVTDAQVAaniDPQAKQSITMAQANKNYMVFiEALKAN 620
Cdd:PRK10788  549 ALPLPAkDKPSYGMAQDMQGNVVLIALDEVTPGSMP---EEQKKAMVQGITQNNAQIAF-EALMSN 610
SurA_N_3 pfam13624
SurA N-terminal domain; This domain is found at the N-terminus of the chaperone SurA. It is a ...
 1-166 1.23e-53

SurA N-terminal domain; This domain is found at the N-terminus of the chaperone SurA. It is a helical domain of unknown function. The C-terminus of the SurA protein folds back and forms part of this domain also but is not included in the current alignment.


Pssm-ID: 433358 [Multi-domain]  Cd Length: 162  Bit Score: 180.46  E-value: 1.23e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537605254   1 MLEKIREGSQGPVAKIILGAVILSFALAGIGSYLGQTTEqPVAEVNGIKISQTDFNRAYQNERSRLEQQFGEYFTQIAAD 80
Cdd:pfam13624   1 MLEFIRKHAKSWIAKIILGLIILSFVFWGVGSYFSGGGG-AVAKVNGEKISRAEFQRAYRRQLDQLRQQFGPNLDAELLD 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537605254  81 PnymAQIRQGVVDRLVQQELQSQLAADLGLRVSDESVRKTILELPYFQIGEKFNNDRYLQVIRQMNFQPDAFREYLRKDM 160
Cdd:pfam13624  80 E---LGLRQQVLDQLIDRALLLQEAKKLGLAVSDEEVRQAIASIPAFQEDGKFDKERYRQLLRANGLTPAEFEASLRQDL 156


                  ....*.
gi 2537605254 161 TRSQVV 166
Cdd:pfam13624 157 LLQQLL 162
SurA COG0760
Peptidyl-prolyl isomerase, parvulin family [Posttranslational modification, protein turnover, ...
 262-397 1.92e-39

Peptidyl-prolyl isomerase, parvulin family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440523 [Multi-domain]  Cd Length: 143  Bit Score: 141.64  E-value: 1.92e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537605254 262 AQYVEPEKRRVSHILI--DNSEDDDAAKEKANALHAQLEQGADFAELAQSSSDDIVSGEMGGDLEWIERDVMDPAFEDAT 339
Cdd:COG0760     1 DQFDSPEEVRASHILVkvPPSEDRAKAEAKAEELLAQLKAGADFAELAKEYSQDPGSAANGGDLGWFSRGQLVPEFEEAA 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2537605254 340 FALQnKGDISEVVASEFGYHIIKLTDIQPQQVKAYDDVKADLRAELEQaEKVDAFYEK 397
Cdd:COG0760    81 FALK-PGEISGPVKTQFGYHIIKVEDRRPAETPPFEEVKQQIRQELFQ-QALEAWLEE 136
prsA PRK00059
peptidylprolyl isomerase; Provisional
 13-400 9.50e-35

peptidylprolyl isomerase; Provisional


Pssm-ID: 234605 [Multi-domain]  Cd Length: 336  Bit Score: 134.45  E-value: 9.50e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537605254  13 VAKIILGAVILSFALAGIGSYLGQTTEQ-----PVAEVNGIKISQTDFNRAYQNER--SRLEQQFGEYFTQIAADPNYMA 85
Cdd:PRK00059    4 IKKLVASLLVGVFIFSAVGCNMIEKTPEaiaksTVATVNGEKITRGDLDKDPKMQQvlEQLKQQYGDNYEKNEQVKEQIK 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537605254  86 QIRQGVVDRLVQQELQSQLAADLGLRVSDESVRKTILE-LPYFQIGEKFNNDRYLQVIRQMNFQPDAFREYLRkdmtrSQ 164
Cdd:PRK00059   84 QQKEQILDSLITEKVLLQKAKELKLIPSEEELNKEVDKkINEIKKQFNNDEEQFEEALKATGFTEETFKEYLK-----NQ 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537605254 165 VVSAiagtdfaleselksaiALQQQtrsidylvinkeaLAANVEVSDQEVSDYYDLNASQFlspelisvsyielkaagin 244
Cdd:PRK00059  159 IIIE----------------KVINE-------------VVKDVKVTDKDAQKYYNENKSKF------------------- 190

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537605254 245 vesvteddvkayyeqnkaqYVEPEKRRVSHILIDNsedddaaKEKANALHAQLEQGADFAELAQSSSDDIVSGEMGGDLE 324
Cdd:PRK00059  191 -------------------TEKPNTMHLAHILVKT-------EDEAKKVKKRLDKGEDFAKVAKEVSQDPGSKDKGGDLG 244

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2537605254 325 WIERDV--MDPAFEDATFALqNKGDISEVVASEFGYHIIKLTDIQPQQVKAYDDVKADLRAELEQAEKVDAFYEKQTE 400
Cdd:PRK00059  245 DVPYSDsgYDKEFMDGAKAL-KEGEISAPVKTQFGYHIIKAIKKKEYPVKPFDSVKEDIKKQLLQEKQSEVFKKKIEE 321
SurA_N_2 pfam13623
SurA N-terminal domain; This domain is found at the N-terminus of the chaperone SurA. It is a ...
 2-142 1.99e-32

SurA N-terminal domain; This domain is found at the N-terminus of the chaperone SurA. It is a helical domain of unknown function. The C-terminus of the SurA protein folds back and forms part of this domain also but is not included in the current alignment.


Pssm-ID: 463938  Cd Length: 145  Bit Score: 121.92  E-value: 1.99e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537605254   2 LEKIREGSQGPVAKIIlGAVILSFA---LAGIGSYLGQTTEQPVAEVNGIKISQTDFNRAYQNERSRLEQQFGEYFTQIA 78
Cdd:pfam13623   1 LQKIREKSGGLLAIII-GLALLAFIigdLFGVGSYLFGGSSNVVAEVNGEEISYQEFQQAVENQRNRLRQQLGQNFDPAE 79

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2537605254  79 ADpnyMAQIRQGVVDRLVQQELQSQLAADLGLRVSDESVRKTILELP----YFQIGE-KFNNDRYLQVI 142
Cdd:pfam13623  80 LD---EAQLREQVWDQLVREKLLLQEAEKLGLTVSDEELVDAIQGNPailqQFQPQTgKFDKQKYQQFL 145
Rotamase_3 pfam13616
PPIC-type PPIASE domain; Rotamases increase the rate of protein folding by catalysing the ...
 267-367 4.48e-27

PPIC-type PPIASE domain; Rotamases increase the rate of protein folding by catalysing the interconversion of cis-proline and trans-proline.


Pssm-ID: 404499 [Multi-domain]  Cd Length: 116  Bit Score: 105.91  E-value: 4.48e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537605254 267 PEKRRVSHILI----DNSEDDDAAKEKANALHAQLEQGADFAELAQSSSDDIVSGEMGGDLEWIERDVMDPAFEDATFAL 342
Cdd:pfam13616  13 PDSVKASHILIsysqAVSRTEEEAKAKADSLLAALKNGADFAALAKTYSDDPASKNNGGDLGWFTKGQMVKEFEDAVFSL 92

                          90       100
                  ....*....|....*....|....*
gi 2537605254 343 qNKGDISEVVASEFGYHIIKLTDIQ 367
Cdd:pfam13616  93 -KVGEISGVVKTQFGFHIIKVTDKK 116
Rotamase pfam00639
PPIC-type PPIASE domain; Rotamases increase the rate of protein folding by catalysing the ...
 274-365 1.28e-25

PPIC-type PPIASE domain; Rotamases increase the rate of protein folding by catalysing the interconversion of cis-proline and trans-proline.


Pssm-ID: 425792 [Multi-domain]  Cd Length: 96  Bit Score: 101.22  E-value: 1.28e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537605254 274 HILI----DNSEDDDAAKEKANALHAQLEQGAD-FAELAQSSSDDIVSGEMGGDLEWIERDVMDPAFEDATFALQnKGDI 348
Cdd:pfam00639   1 HILIktpeASERDRAEAKAKAEEILEQLKSGEDsFAELARKYSDDCPSAANGGDLGWFTRGQLPPEFEKAAFALK-PGEI 79

                          90
                  ....*....|....*..
gi 2537605254 349 SEVVASEFGYHIIKLTD 365
Cdd:pfam00639  80 SGPVETRFGFHIIKLTD 96
prsA PRK03002
peptidylprolyl isomerase PrsA;
246-410 5.85e-23

peptidylprolyl isomerase PrsA;


Pssm-ID: 101162 [Multi-domain]  Cd Length: 285  Bit Score: 99.24  E-value: 5.85e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537605254 246 ESVTEDDVKAYYEqnkaqyvePEKRrVSHILIDNsedddaaKEKANALHAQLEQGADFAELAQSSSDDIVSGEMGGDLEW 325
Cdd:PRK03002  122 KSVTEKDVKDHYK--------PEIK-ASHILVSD-------ENEAKEIKKKLDAGASFEELAKQESQDLLSKEKGGDLGY 185

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537605254 326 IERDVMDPAFEDATFALqNKGDISEVVASEFGYHIIKLTDiqPQQVKAYDDVKADLRAELEQAEKVDAFYEK---QTEMG 402
Cdd:PRK03002  186 FNSGRMAPEFETAAYKL-KVGQISNPVKSPNGYHIIKLTD--KKDLKPYDEVKDSIRKNLEEERTADPIFGKkllQSELK 262


                  ....*...
gi 2537605254 403 ALAFEISD 410
Cdd:PRK03002  263 KANIKIND 270
prsA PRK03095
peptidylprolyl isomerase PrsA;
179-393 1.56e-20

peptidylprolyl isomerase PrsA;


Pssm-ID: 179537 [Multi-domain]  Cd Length: 287  Bit Score: 92.36  E-value: 1.56e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537605254 179 ELKSAIALQQQTRSIDYLVINKeALAANVEVSDQEVSDYYD------------LNASQFLSPELISVSYIELKAAGINVE 246
Cdd:PRK03095   39 EFYEQMKTQAGKQVLNNMVMEK-VLIKNYKVEDKEVDKKYDemkkqygdqfdtLLKQQGIKEETLKTGVRAQLAQEKAIE 117

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537605254 247 -SVTEDDVKAYYEQnkaqyvepeKRRVSHILIDNSEDDDAAKEkanalhaQLEQGADFAELAQSSSDDIVSGEMGGDLEW 325
Cdd:PRK03095  118 kTITDKELKDNYKP---------EIKASHILVKDEATAKKVKE-------ELGQGKSFEELAKQYSEDTGSKEKGGDLGF 181

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2537605254 326 IERDVMDPAFEDATFALQnKGDISEVVASEFGYHIIKLTDIQPQQvKAYDDVKADLRAELEQAEKVDA 393
Cdd:PRK03095  182 FGAGKMVKEFEDAAYKLK-KDEVSEPVKSQFGYHIIKVTDIKEPE-KSFEQSKADIKKELVQKKAQDG 247
prsA PRK02998
peptidylprolyl isomerase; Reviewed
 247-426 4.19e-19

peptidylprolyl isomerase; Reviewed


Pssm-ID: 179522 [Multi-domain]  Cd Length: 283  Bit Score: 88.10  E-value: 4.19e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537605254 247 SVTEDDVKAYYEqnkaqyvepEKRRVSHILIDNSEDDDAAKEKANalhaqleQGADFAELAQSSSDDIVSGEMGGDLEWI 326
Cdd:PRK02998  121 TVTEKDVKDNYK---------PEMKVSHILVKDEKTAKEVKEKVN-------NGEDFAALAKQYSEDTGSKEQGGEISGF 184

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537605254 327 ERDVMDPAFEDATFALQnKGDISEVVASEFGYHIIKLTDiqPQQVKAYDDVKADLRAELEQAEKVDAFYEKQTEMgalaf 406
Cdd:PRK02998  185 APGQTVKEFEEAAYKLD-AGQVSEPVKTTYGYHIIKVTD--KKELKPFDEVKDSIRKDLEQQRLQDTTGKWKQQV----- 256

                         170       180
                  ....*....|....*....|.
gi 2537605254 407 eISDRLDDA-AEVAEVEVKST 426
Cdd:PRK02998  257 -VNDLLKDAdIKVNDKEFKDT 276
Rotamase_2 pfam13145
PPIC-type PPIASE domain;
248-378 3.17e-18

PPIC-type PPIASE domain;


Pssm-ID: 432992 [Multi-domain]  Cd Length: 121  Bit Score: 80.95  E-value: 3.17e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537605254 248 VTEDDVKAYYEQNKAQYVEPEKRRVSHILIDNSEDDDAAKEKANAlhaqlEQGADFAELAQSSSDDIvsgemgGDLEWIE 327
Cdd:pfam13145   1 VTEEELKAYYEENKDEFSTPEGRLLEILVFKDQVAADAALALLKA-----GALEDFAALAKGEGIKA------ATLDIVE 69

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2537605254 328 RD-VMDPAFEDATFALqNKGDISEVVASEFGYHIIKLTDIQPQQVKAYDDVK 378
Cdd:pfam13145  70 SAeLLPEELAKAAFAL-KPGEVSGPIKTGNGYYVVRVTEIKPAQPLPFEEAK 120
PTZ00356 PTZ00356
peptidyl-prolyl cis-trans isomerase (PPIase); Provisional
 265-362 1.80e-13

peptidyl-prolyl cis-trans isomerase (PPIase); Provisional


Pssm-ID: 185573 [Multi-domain]  Cd Length: 115  Bit Score: 66.97  E-value: 1.80e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537605254 265 VEPEKRRVSHILIDNSE----------------DDDAAKEKAnALHAQLEQGA-DFAELAQSSSDdIVSGEMGGDLEWIE 327
Cdd:PTZ00356    1 MEGDTVRAAHLLIKHTGsrnpvsrrtgkpvtrsKEEAIKELA-KWREQIVSGEkTFEEIARQRSD-CGSAAKGGDLGFFG 78

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 2537605254 328 RDVMDPAFEDATFALQnKGDISEVVASEFGYHIIK 362
Cdd:PTZ00356   79 RGQMQKPFEDAAFALK-VGEISDIVHTDSGVHIIL 112
PRK10770 PRK10770
peptidyl-prolyl cis-trans isomerase SurA; Provisional
 274-365 4.24e-13

peptidyl-prolyl cis-trans isomerase SurA; Provisional


Pssm-ID: 236758 [Multi-domain]  Cd Length: 413  Bit Score: 71.70  E-value: 4.24e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537605254 274 HILIDNSE--DDDAAKEKANALHAQLEQG-ADFAELAQSSSDDIVSGEMGGDLEWIERDVMDPAFEDATFALqNKGDISE 350
Cdd:PRK10770  271 HILLKPSPimTDEQARAKLEQIAADIKSGkTTFAAAAKEFSQDPGSANQGGDLGWATPDIFDPAFRDALMRL-NKGQISA 349

                          90
                  ....*....|....*
gi 2537605254 351 VVASEFGYHIIKLTD 365
Cdd:PRK10770  350 PVHSSFGWHLIELLD 364
PRK15441 PRK15441
peptidyl-prolyl cis-trans isomerase C; Provisional
 274-363 8.19e-08

peptidyl-prolyl cis-trans isomerase C; Provisional


Pssm-ID: 185338 [Multi-domain]  Cd Length: 93  Bit Score: 50.41  E-value: 8.19e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537605254 274 HILIdnsedddaaKEKANALH--AQLEQGADFAELAQSSSDdIVSGEMGGDLEWIERDVMDPAFEDATFA---LQNKGDI 348
Cdd:PRK15441    9 HILV---------KEEKLALDllEQIKNGADFGKLAKKHSI-CPSGKRGGDLGEFRQGQMVPAFDKVVFScpvLEPTGPL 78

                          90
                  ....*....|....*
gi 2537605254 349 SevvaSEFGYHIIKL 363
Cdd:PRK15441   79 H----TQFGYHIIKV 89
prsA PRK04405
peptidylprolyl isomerase; Provisional
 178-363 4.11e-07

peptidylprolyl isomerase; Provisional


Pssm-ID: 235295 [Multi-domain]  Cd Length: 298  Bit Score: 52.09  E-value: 4.11e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537605254 178 SELKSAIALQQQTRSidyLVINKeALAANV--EVSDQEVSDYYDLNASQ-------FLSPELISVSYIE--------LKA 240
Cdd:PRK04405   46 KEMKQSSAGKTVLAN---MIIYR-ALEKQYgkKVSTKKVDKQYNSYKKQygssfdsVLSQNGMTTSSFKqnlrtnllSEA 121

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537605254 241 AGINVESVTEDDVKAYYEQnkaqyVEPeKRRVSHILIdnsedddAAKEKANALHAQLEQGADFAELAQSSSDDIVSGEMG 320
Cdd:PRK04405  122 ALKKLKKVTNSQLKKAWKS-----YQP-KVTVQHILV-------SKKSTAETVIKKLKDGKDFAKLAKKYSTDTATKNKG 188

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 2537605254 321 GDLEWIER--DVMDPAFEDATFALQNKGDISEVVASEFGYHIIKL 363
Cdd:PRK04405  189 GKLSAFDStdTTLDSTFKTAAFKLKNGEYTTTPVKTTYGYEVIKM 233
PRK10770 PRK10770
peptidyl-prolyl cis-trans isomerase SurA; Provisional
 252-367 9.93e-06

peptidyl-prolyl cis-trans isomerase SurA; Provisional


Pssm-ID: 236758 [Multi-domain]  Cd Length: 413  Bit Score: 48.20  E-value: 9.93e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537605254 252 DVKAYYEQNKAQYVEPEKRRVSHILIDNSEDD-----DAAKEKANALHAQLEQGADFAELAQSSSDD---IVSGEMGgdl 323
Cdd:PRK10770  138 EVDSLAKQIGNQNDASTELNLSHILIPLPENPtqdqvDEAESQARSIVDQARNGADFGKLAIAYSADqqaLKGGQMG--- 214

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 2537605254 324 eWIERDVMDPAFEDatfALQN--KGDISEVVASEFGYHIIKLTDIQ 367
Cdd:PRK10770  215 -WGRIQELPGLFAQ---ALSTakKGDIVGPIRSGVGFHILKVNDLR 256
SurA_N pfam09312
SurA N-terminal domain; This domain is found at the N-terminus of the chaperone SurA. It is a ...
 42-165 1.64e-03

SurA N-terminal domain; This domain is found at the N-terminus of the chaperone SurA. It is a helical domain of unknown function. The C-terminus of the SurA protein folds back and forms part of this domain also but is not included in the current alignment.


Pssm-ID: 430518 [Multi-domain]  Cd Length: 118  Bit Score: 38.80  E-value: 1.64e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537605254  42 VAEVNGIKISQTDFNRAYQNERSRLEQQFgeyfTQIAADpnymAQIRQGVVDRLVQQELQSQLAADLGLRVSDESVRKTI 121
Cdd:pfam09312   5 VAVVNDGVILQSELDRRVDTVKRNLQQQG----TQLPPD----AVLERQVLERLILERIQLQMAEKTGIRVDDAELNQAI 76

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 2537605254 122 LELPyfqigeKFNN---DRYLQVIRQMNFQPDAFREYLRKDMTRSQV 165
Cdd:pfam09312  77 ARIA------QQNNltlDQLRQALAADGLSYDKFREQIRKEIIISRL 117
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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