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Conserved domains on  [gi|2538030866|ref|WP_294397760|]
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TonB-dependent receptor domain-containing protein [Prosthecobacter sp.]

Protein Classification

TonB-dependent receptor family protein( domain architecture ID 11469151)

TonB-dependent receptor family protein such as Escherichia coli Fe(3+) dicitrate transport protein FecA which is the outer membrane receptor protein in the Fe(3+) dicitrate transport system

Gene Ontology:  GO:0038023|GO:0009279|GO:0015343|GO:0015891
PubMed:  12948487
TCDB:  1.B.14

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
FecA COG4772
Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];
26-714 9.24e-128

Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];


:

Pssm-ID: 443804 [Multi-domain]  Cd Length: 681  Bit Score: 394.68  E-value: 9.24e-128
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866  26 AIASHARSQSVSKPKLVTELPNVVITADAPEEPQVK-IPylppveGTkiyagkrASIIELKALPEVISNNYRQAFALTPG 104
Cdd:COG4772     4 ALAAALLLAAAAAAEAATTLETVVVTGSRAAEARLKdVP------GS-------VSVVDREELENQAATSLREVLRRVPG 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 105 LLVAEETTPLVSL--GYRGIGgPDRAQFMQILQDGIPISADPIGYPEAYWTPQLESVQRIDFLRGGASLLYGPQPA-GAL 181
Cdd:COG4772    71 VNVQEEDGFGLRPniGIRGLG-PRRSRGITLLEDGIPIAPAPYGDPAAYYFPDLERMERIEVLRGAAALRYGPQTVgGAI 149

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 182 NYVTLMPRADKPLGVRQQFimGTDDLISSYTSMDGTIGKLGYHGYFAHRSADGFRQaNSDYETNGGRVKLVYQQDEDTRW 261
Cdd:COG4772   150 NFVTRTIPTAFGGELRVTG--GSFGYRRTHASVGGTVGNFGYLVEYSRKRGDGFRD-NSGFDINDFNAKLGYRLSDRQEL 226

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 262 IFGLEAFQQENGEPGGLSSAGYAADRNQTVRFNDRFKLSRYAMSIELQHRMSSDTELCIKTWAAYYDR-WSRRQNGGGFG 340
Cdd:COG4772   227 TLKFQYYDEDANTPGGLTDAQFDADPRQSYRPADQFDTRRTQLSLRYEHQLSDNTTLTTTAYYNDFSRnWYIRQNTADPN 306

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 341 IVPVGVTTSiDRQeFYNWGIEPRIRHDYEAWGGKHTISAGMHFYLSHSPTTTKTGATVTSNDGPILRdaqRDIIYG---- 416
Cdd:COG4772   307 TPGLGLRGN-PRG-YRSYGIEPRLTHRFELGGVPHTLEVGLRYHREEEDRKQYVNTYGQGRSGAGLR---RDRRFSadal 381

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 417 AVFVENKFTF-GRLTITPGFRMELVNQDMTlQNFAVGAVPETNNSKFDSQPLFGLGLAYDLGSETMLYANISQSYRATTF 495
Cdd:COG4772   382 AAYAQNRFELtGRLTLTPGLRYEHIRRDRT-DRYSTRTGGDDSGSNSYSEFLPGLGLLYQLTDNLQLYANVSRGFEPPTF 460

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 496 SQSLIPAagGTANDAAPSLGWHYELGMRGTPRPWITWDSAFFLIDLDNKFGT------TGTALTSVGRSINYGWDGALQF 569
Cdd:COG4772   461 GDLAYGN--GGNPDLKPEKSWNYELGTRGRIGNGLSAEVALFYIDYDNELGScsaaggDRSTFTNAGETRHQGLELALDY 538

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 570 DVigaldaangthRGDRLGALNLYANASLLEARL--SGGPNNGGTPQ-FAPPYMVRTGVIYSRKsKLKLAFLGTLM--AR 644
Cdd:COG4772   539 DL-----------LKGGGLGLPLFAAYTYTDAEFtsDFGPVFAGNRLpYVPRHQLTAGLGYEHG-GWTANLNGRYVseQF 606

                         650       660       670       680       690       700       710
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2538030866 645 HSGSDTAAAGFD--IPAYTTWDLTAEIPVTQNLKLIGGLNNVFDKQYFARV---NAGGIDPAYGRNFYVGGSLTF 714
Cdd:COG4772   607 TDAANTVADGSFgkIPSYTVLDLSASYDFGKNLSLFAGVNNLFDKRYIASRapnYAAGIRPGPPRTVYAGLRLKF 681
 
Name Accession Description Interval E-value
FecA COG4772
Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];
26-714 9.24e-128

Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];


Pssm-ID: 443804 [Multi-domain]  Cd Length: 681  Bit Score: 394.68  E-value: 9.24e-128
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866  26 AIASHARSQSVSKPKLVTELPNVVITADAPEEPQVK-IPylppveGTkiyagkrASIIELKALPEVISNNYRQAFALTPG 104
Cdd:COG4772     4 ALAAALLLAAAAAAEAATTLETVVVTGSRAAEARLKdVP------GS-------VSVVDREELENQAATSLREVLRRVPG 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 105 LLVAEETTPLVSL--GYRGIGgPDRAQFMQILQDGIPISADPIGYPEAYWTPQLESVQRIDFLRGGASLLYGPQPA-GAL 181
Cdd:COG4772    71 VNVQEEDGFGLRPniGIRGLG-PRRSRGITLLEDGIPIAPAPYGDPAAYYFPDLERMERIEVLRGAAALRYGPQTVgGAI 149

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 182 NYVTLMPRADKPLGVRQQFimGTDDLISSYTSMDGTIGKLGYHGYFAHRSADGFRQaNSDYETNGGRVKLVYQQDEDTRW 261
Cdd:COG4772   150 NFVTRTIPTAFGGELRVTG--GSFGYRRTHASVGGTVGNFGYLVEYSRKRGDGFRD-NSGFDINDFNAKLGYRLSDRQEL 226

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 262 IFGLEAFQQENGEPGGLSSAGYAADRNQTVRFNDRFKLSRYAMSIELQHRMSSDTELCIKTWAAYYDR-WSRRQNGGGFG 340
Cdd:COG4772   227 TLKFQYYDEDANTPGGLTDAQFDADPRQSYRPADQFDTRRTQLSLRYEHQLSDNTTLTTTAYYNDFSRnWYIRQNTADPN 306

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 341 IVPVGVTTSiDRQeFYNWGIEPRIRHDYEAWGGKHTISAGMHFYLSHSPTTTKTGATVTSNDGPILRdaqRDIIYG---- 416
Cdd:COG4772   307 TPGLGLRGN-PRG-YRSYGIEPRLTHRFELGGVPHTLEVGLRYHREEEDRKQYVNTYGQGRSGAGLR---RDRRFSadal 381

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 417 AVFVENKFTF-GRLTITPGFRMELVNQDMTlQNFAVGAVPETNNSKFDSQPLFGLGLAYDLGSETMLYANISQSYRATTF 495
Cdd:COG4772   382 AAYAQNRFELtGRLTLTPGLRYEHIRRDRT-DRYSTRTGGDDSGSNSYSEFLPGLGLLYQLTDNLQLYANVSRGFEPPTF 460

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 496 SQSLIPAagGTANDAAPSLGWHYELGMRGTPRPWITWDSAFFLIDLDNKFGT------TGTALTSVGRSINYGWDGALQF 569
Cdd:COG4772   461 GDLAYGN--GGNPDLKPEKSWNYELGTRGRIGNGLSAEVALFYIDYDNELGScsaaggDRSTFTNAGETRHQGLELALDY 538

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 570 DVigaldaangthRGDRLGALNLYANASLLEARL--SGGPNNGGTPQ-FAPPYMVRTGVIYSRKsKLKLAFLGTLM--AR 644
Cdd:COG4772   539 DL-----------LKGGGLGLPLFAAYTYTDAEFtsDFGPVFAGNRLpYVPRHQLTAGLGYEHG-GWTANLNGRYVseQF 606

                         650       660       670       680       690       700       710
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2538030866 645 HSGSDTAAAGFD--IPAYTTWDLTAEIPVTQNLKLIGGLNNVFDKQYFARV---NAGGIDPAYGRNFYVGGSLTF 714
Cdd:COG4772   607 TDAANTVADGSFgkIPSYTVLDLSASYDFGKNLSLFAGVNNLFDKRYIASRapnYAAGIRPGPPRTVYAGLRLKF 681
ligand_gated_channel cd01347
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ...
 110-714 9.21e-47

TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.


Pssm-ID: 238657 [Multi-domain]  Cd Length: 635  Bit Score: 176.10  E-value: 9.21e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 110 ETTPLVSLGYRGIGGPDR-------AQFMQILQDGIPISADPIGYPEAYWTPQLESVQRIDFLRGGASLLYGPQ-PAGAL 181
Cdd:cd01347    23 RRIPGVSVTRGGGGGGSTisirgfgPDRTLVLVDGLPLASSNYGRGVDLNTIPPELIERVEVLKGPSSALYGSGaIGGVV 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 182 NYVTlmPRADKPLGVRQQFIMGTDDLISSYTSMDGTIGKLGYHGYFAHRSADGFRQAN-----------SDYETNGGRVK 250
Cdd:cd01347   103 NIIT--KRPTDEFGGSVTAGYGSDNSGSSGGGGFDVSGALADDGAFGARLYGAYRDGDgtidgdgqaddSDEERYNVAGK 180

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 251 LVYQQDEDTRWIFGLEAFQQENGEPGGLSSAGYAA--------DRNQTVRFNDRFKLSRYAMSIELQHRmSSDTELCIKT 322
Cdd:cd01347   181 LDWRPDDDTRLTLDAGYQDQDADGPGGTLPANGTGsslgggpsSNTNGDRDWDYRDRYRKRASLGLEHD-LNDTGWTLRA 259

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 323 WAAY-YDRWSRRQNGGGFGIVPVGVTTSIDRQEFY----NWGIEPRIRHDYEAWGGKHTISAGMHFylshsptttktgat 397
Cdd:cd01347   260 NLSYsYTDNDGDPLILNGGNNAAGGDLGRSGYSSErdttQLGFDAGLNAPFGTGPVAHTLTLGVEY-------------- 325

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 398 vtsndgpilRDAQRDIIYGAVFVENKFTFG-RLTITPGFRMELVNQDMTLQNfavgaVPETNNSKFDSQPLFGLGLAYDL 476
Cdd:cd01347   326 ---------RREELDEKQTALYAQDTIELTdDLTLTLGLRYDHYDQDSKDTI-----AGGTTAKKSYSHWSPSLGLVYKL 391

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 477 GSETMLYANISQSYRA-----TTFSQSLIPAAGGTANDAAPSLGWHYELGMRGTPRPWITWDSAFFLIDLDNK--FGTTG 549
Cdd:cd01347   392 TDGLSLYASYSQGFRApslgeLYGGGSHGGTAAVGNPNLKPEKSKQYELGLKYDPGDGLTLSAALFRIDIKNEivSTPTN 471

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 550 TALTSVGRSIN------YGWDGALQFDVIGALdaangthrgdrlgalNLYANASLL--EARLSGGPNNGGTPQFAPPYMV 621
Cdd:cd01347   472 TGLGLVTVYVNggkariRGVELEASYDLTDGL---------------GLTGSYTYTdtEVKRTDGATTGNRLPGIPKHTA 536

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 622 RTGVIYSRKSKlklAFLGTLMARHSGSDTA-----AAGFDIPAYTTWDLTAEIPVTQNLKLIGGLNNVFDKQYFARVNAG 696
Cdd:cd01347   537 NLGLDYELPDE---GLTAGGGVRYRGKQYAdtangNNTVKVPGYTLVDLSASYQFTKNLTLRLGVNNLFDKDYYTSLSVR 613

                         650       660
                  ....*....|....*....|..
gi 2538030866 697 GID----PAYGRNFYVGGSLTF 714
Cdd:cd01347   614 GSGlygyYGPGRTYYLSVSYKF 635
TonB-siderophor TIGR01783
TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of ...
 79-714 2.86e-41

TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of TonB-dependent outer membrane siderophore receptors. It has no overlap with TonB receptors known to transport other substances, but is likely incomplete due to lack of characterizations. It is likely that genuine siderophore receptors will be identified which score below the noise cutoff to this model at which point the model should be updated. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273805 [Multi-domain]  Cd Length: 651  Bit Score: 160.27  E-value: 2.86e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866  79 ASIIELKALPEVISNNYRQAFALTPGLLVAEE--TTPLVSLGYRGIGGpdRAQFMQILQDGIPISADPIGYPEAywtpqL 156
Cdd:TIGR01783   6 VSVITRQELEDQQAGSLSEALQRVPGVVVGGSggTTQFGNITIRGFGL--EVDIDNVYLDGVPLLSRGNLAIVD-----P 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 157 ESVQRIDFLRGGASLLYGPQ-PAGALNYVTLMPRaDKPLGVrQQFIMGTDDLISSYTSMDGTIG---KLGYHGYFAHRSA 232
Cdd:TIGR01783  79 AMVERVEVLRGPASLLYGGSaPGGVINIVTKRPQ-DEPKGS-VTFGAGTRSGYRTAFDLGGPLGadgTFRGRLNGARQDG 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 233 DGFRqANSDYETNGGRVKLVYQQDEDTRWIFGLEaFQQENGEP--------GGLSSAGYAADRNQTV---RFNDRFKLSR 301
Cdd:TIGR01783 157 DSFY-DGAGEETRLGATATDWQLDDRTLLRLGAY-YQKERDRGgygglpasGGTSGRDLSSDRYLGTssnRNYDDREYLS 234

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 302 YAMSIELQHRmssdtelciKTWAAYYD-RWSR-------------RQNGGGFGIVPVGVTTSIDRqefynWGIEPRIRHD 367
Cdd:TIGR01783 235 YGLSLEYQFN---------DVWTGKQNlRYSYfdtdsnqvqasgySSDGGLFGRSLTVVNVKQDR-----VQIDAGLDGE 300

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 368 YEAWGGKHTISAG------------MHFYLSHSPTTTKTGATVTSNDGPILRD-AQRDIIY--GAVFVENKFTFGRLTIT 432
Cdd:TIGR01783 301 FETGPIEHDLLLGvsygqrttnrfnNTGYPSDNIYSLTATSSARTDIGDSPKDrALSSTTKalNGVALQRILLADKWTLT 380

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 433 PGFRMELVNQDmtlqnfAVGAVPETNNSKFDSQPLFGLGLAYDLGSETMLYANISQSYRAttfSQSLIPAAGGTANDAAP 512
Cdd:TIGR01783 381 LGGRYDSVDVK------SNNGVAGSTGKRDDSQFTPSLGVAYKPTDDWSLYASYAESFKP---GGYYPKGAGNSGDILEP 451

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 513 SLGWHYELGMRGTPRPWITWDSAFFLIDLDNKF---GTTGTALTSVGRSINYGwdgaLQFDVIGALdaangthrgdrLGA 589
Cdd:TIGR01783 452 EKGKNYELGVRYDLGDSLLATAALFRITKDNQLvqdPVNGTFSVNAGKTRNRG----VELEARGYL-----------TPG 516

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 590 LNLYANASLLEARL---SGGPNNGGTPQFAPPYMVRTGVIYS---RKSKLKLAFLGTLMARHSGSDtaAAGFDIPAYTTW 663
Cdd:TIGR01783 517 LSLSAGYTYTDAEFtedTNGDTQGNTVPFVPKHTASLWASYAppvGDNGLTLGGGVQYTGKAYVDG--GNTGKVPSYTVV 594

                         650       660       670       680       690
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2538030866 664 DLTA--EIPVTQNLKLIGGLNNVFDKQYFARV----NAGGIDPAYGRNFYVGGSLTF 714
Cdd:TIGR01783 595 DLSVryDLTKKKNLTLALNVNNLFDRDYYTSGyrwgPSAYIYPGAPRTVGLSVSYDF 651
TonB_dep_Rec pfam00593
TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
 272-713 6.70e-30

TonB dependent receptor; This model now only covers the conserved part of the barrel structure.


Pssm-ID: 395474 [Multi-domain]  Cd Length: 475  Bit Score: 124.11  E-value: 6.70e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 272 NGEPGGLSSAGYAADRNQTVRFNDRFKLSRYAMSIELQHRMSSDTELCIKTWAAYYDRWSRR--QNGGGFGIVPVGVTTS 349
Cdd:pfam00593  33 TLDGYGNDGGYLGDRPLYYGRDYSDTDRKRLSLGYDYDLGDGLSWLSTLRLGLRYSSLDGDYtsNSSGLSGAGDYLSDDR 112

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 350 IDRQEFYNWGIEPRIRHDYEAWGGKHTISAGMHFYLSHSPTTTKTGATVTSNDGPILRDAQRdiiyGAVFVENKFTF-GR 428
Cdd:pfam00593 113 LYGLYGLDGDLELSLDLSHDLLLGVELRTAGLDYRRLDDDAYDPYDPANPSSSSYSDTTTDS----YGLYLQDNIKLtDR 188

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 429 LTITPGFRMELVNQDMTLQNfavgaVPETNNSKFDSQPLFGLGLAYDLGSETMLYANISQSYRATTFSQ---SLIPAAGG 505
Cdd:pfam00593 189 LTLTLGLRYDHYSTDGDDGN-----GGGDNFSRSYSAFSPRLGLVYKPTDNLSLYASYSRGFRAPSLGElygSGSGGGGG 263

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 506 TANDAAPSL----GWHYELGMRGTPRpWITWDSAFFLIDLDNK---------FGTTGTALTSVGRSINYGWDGALQfdvi 572
Cdd:pfam00593 264 AVAGGNPDLkpetSDNYELGLKYDDG-RLSLSLALFYIDIKNLitsdpdgpgLGGTVYTYTNVGKARIRGVELELS---- 338

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 573 galdaangthrGDRLGALNLYANASLLEARLSGGPNNGGTP-QFAPPYMVRTGVIYSrksKLKLAFLGTLMARHSGSDT- 650
Cdd:pfam00593 339 -----------GRLWGLGLSGGGYTYTDADDDADADDTGNPlPNVPRHTANLGLTYD---FPLGGWGARLGARYVGSGEr 404

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2538030866 651 ----AAAGFDIPAYTTWDLTAEIPVTQNLKLIGGLNNVFDKQYFARVNAGGID----PAYGRNFYVGGSLT 713
Cdd:pfam00593 405 rygdAANTFKTPGYTLVDLSAGYRLNKNLTLRLGVNNLFDKYYKRYYSSGGGNlggyPGPGRTFYLGLSYK 475
PRK13513 PRK13513
ligand-gated channel protein;
25-714 5.03e-07

ligand-gated channel protein;


Pssm-ID: 184104 [Multi-domain]  Cd Length: 659  Bit Score: 53.23  E-value: 5.03e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866  25 LAIASHARSQSVSKPKLVTELPN--VVITADAPEEpqvKIPYLPpvegtkiyagkrASI-------IELKALPEVISnny 95
Cdd:PRK13513   13 LVIAAAISSQAYAAEKTNTATPTdtMVVTASGFQQ---RIQDAP------------ASIsvvtreqLENKAYRDVTD--- 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866  96 rqAFALTPGLLVAE-ETTPLVSLgyRGIGgpdrAQFMQILQDGIPIS-------ADPIGYpEAYWTPQLESVQRIDFLRG 167
Cdd:PRK13513   75 --ALKDVPGVVVTGgGSTSDISI--RGMA----AKYTLILVDGKRVDtrstrpnSDGSGI-EQGWLPPLAAIERIEVVRG 145

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 168 GASLLYGPQP-AGALNYVTLMP--------RADKPLGVRQQfiMGTDDLISSYTS---MDGTIGkLGYHGYFAHRSADGF 235
Cdd:PRK13513  146 PMSSLYGSDAmGGVINIITRKVqkewhgslRADATLQEDSK--SGDIFQTNAYASgplIDGLLG-LKVSGLLSHRSEDKI 222

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 236 RQANSDYETNGGRVKLVYQQDEDTRWIFGLEAFQQENGepgglSSAGYAADRNQTVRFNdRFKLSRYAMsielqhrmssd 315
Cdd:PRK13513  223 IDGYNEQRMRNGTATFSLTPDDNNEFDFEIGRYVQDRN-----STPGRTLALNGTNSDT-QYDRNNYAI----------- 285

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 316 telcikTWAAYYDrwsrrqngggFGivpvGVTTSIDRQEFYNWGIEprIRHDYEAWGGKHTISAGMHfYLSHSPTTTKTG 395
Cdd:PRK13513  286 ------THNGYYD----------FG----NSTSYIQRDETRNPSRQ--MKSVDTIFNTQTSFLLDDH-TLSLGGQYRYEE 342

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 396 ATVTSNDGPILRDAQRDIIYG-AVFVENKFTF-GRLTITPGFRMelvNQDmtlQNFAVGAVPEtnnskfdsqpLFGLgla 473
Cdd:PRK13513  343 LYDKGNQLPSASDLNKLTRWSwALFAEDEWQMtNDFALTGGIRM---DQD---QNYGTHWTPR----------LYGV--- 403

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 474 YDLGSETMLYANISQSYRATTFSQSLIP----AAGGTAN-------DAAPSLGWHYELGmrgtprpwITWDS-------- 534
Cdd:PRK13513  404 WHLADQWTLKGGVSTGYRSPDLRQATDNwgqlTGGGGLPalilgnsDLKPEKSISQEIG--------ILWDNqenlnasv 475

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 535 AFFLIDLDNKfgttgtaLTSVGRSINYGWDGALQ-----FDVIGA---LDAAN-----GTHRGDRLGALNLYANASLLEA 601
Cdd:PRK13513  476 TLFNTDFKDK-------ITEVRNCDTTNTDGQCVfnginYDFISDrinVDKANmrgveATFNWDINQAWSLATNYTFTQS 548

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 602 RLSGGPNNGGTPQFAPPYMVRTGVIYSRKSKL----KLAFLGTLMARHSGSDTAAAgfdIPAYTTWDLTAEIPVTQNLKL 677
Cdd:PRK13513  549 EQKSGAFAGQPLNQMPKHMANATLNWQTTEDFatwiRINYRGKTSEYLNRTSMGSG---TPSYTFVDLGASYQLTKELRL 625

                         730       740       750
                  ....*....|....*....|....*....|....*..
gi 2538030866 678 IGGLNNVFDKQYFARVNAGGIDpayGRNFYVGGSLTF 714
Cdd:PRK13513  626 MGGVYNLLDKRVDIDVNDKVLD---GRRYMVGASYDF 659
 
Name Accession Description Interval E-value
FecA COG4772
Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];
26-714 9.24e-128

Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];


Pssm-ID: 443804 [Multi-domain]  Cd Length: 681  Bit Score: 394.68  E-value: 9.24e-128
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866  26 AIASHARSQSVSKPKLVTELPNVVITADAPEEPQVK-IPylppveGTkiyagkrASIIELKALPEVISNNYRQAFALTPG 104
Cdd:COG4772     4 ALAAALLLAAAAAAEAATTLETVVVTGSRAAEARLKdVP------GS-------VSVVDREELENQAATSLREVLRRVPG 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 105 LLVAEETTPLVSL--GYRGIGgPDRAQFMQILQDGIPISADPIGYPEAYWTPQLESVQRIDFLRGGASLLYGPQPA-GAL 181
Cdd:COG4772    71 VNVQEEDGFGLRPniGIRGLG-PRRSRGITLLEDGIPIAPAPYGDPAAYYFPDLERMERIEVLRGAAALRYGPQTVgGAI 149

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 182 NYVTLMPRADKPLGVRQQFimGTDDLISSYTSMDGTIGKLGYHGYFAHRSADGFRQaNSDYETNGGRVKLVYQQDEDTRW 261
Cdd:COG4772   150 NFVTRTIPTAFGGELRVTG--GSFGYRRTHASVGGTVGNFGYLVEYSRKRGDGFRD-NSGFDINDFNAKLGYRLSDRQEL 226

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 262 IFGLEAFQQENGEPGGLSSAGYAADRNQTVRFNDRFKLSRYAMSIELQHRMSSDTELCIKTWAAYYDR-WSRRQNGGGFG 340
Cdd:COG4772   227 TLKFQYYDEDANTPGGLTDAQFDADPRQSYRPADQFDTRRTQLSLRYEHQLSDNTTLTTTAYYNDFSRnWYIRQNTADPN 306

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 341 IVPVGVTTSiDRQeFYNWGIEPRIRHDYEAWGGKHTISAGMHFYLSHSPTTTKTGATVTSNDGPILRdaqRDIIYG---- 416
Cdd:COG4772   307 TPGLGLRGN-PRG-YRSYGIEPRLTHRFELGGVPHTLEVGLRYHREEEDRKQYVNTYGQGRSGAGLR---RDRRFSadal 381

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 417 AVFVENKFTF-GRLTITPGFRMELVNQDMTlQNFAVGAVPETNNSKFDSQPLFGLGLAYDLGSETMLYANISQSYRATTF 495
Cdd:COG4772   382 AAYAQNRFELtGRLTLTPGLRYEHIRRDRT-DRYSTRTGGDDSGSNSYSEFLPGLGLLYQLTDNLQLYANVSRGFEPPTF 460

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 496 SQSLIPAagGTANDAAPSLGWHYELGMRGTPRPWITWDSAFFLIDLDNKFGT------TGTALTSVGRSINYGWDGALQF 569
Cdd:COG4772   461 GDLAYGN--GGNPDLKPEKSWNYELGTRGRIGNGLSAEVALFYIDYDNELGScsaaggDRSTFTNAGETRHQGLELALDY 538

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 570 DVigaldaangthRGDRLGALNLYANASLLEARL--SGGPNNGGTPQ-FAPPYMVRTGVIYSRKsKLKLAFLGTLM--AR 644
Cdd:COG4772   539 DL-----------LKGGGLGLPLFAAYTYTDAEFtsDFGPVFAGNRLpYVPRHQLTAGLGYEHG-GWTANLNGRYVseQF 606

                         650       660       670       680       690       700       710
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2538030866 645 HSGSDTAAAGFD--IPAYTTWDLTAEIPVTQNLKLIGGLNNVFDKQYFARV---NAGGIDPAYGRNFYVGGSLTF 714
Cdd:COG4772   607 TDAANTVADGSFgkIPSYTVLDLSASYDFGKNLSLFAGVNNLFDKRYIASRapnYAAGIRPGPPRTVYAGLRLKF 681
CirA COG1629
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];
45-702 2.63e-67

Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];


Pssm-ID: 441236 [Multi-domain]  Cd Length: 644  Bit Score: 233.57  E-value: 2.63e-67
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866  45 LPNVVITADAPEEPQVKIPylppvegtkiyagKRASIIELKALPEVISNNYRQAFALTPGLLVAEETTPLVSLGYRGIGG 124
Cdd:COG1629     1 LEEVVVTATRTDESLQDVP-------------GSVSVISREQLEDQPATDLGDLLRRVPGVSVTSAGGGAGQISIRGFGG 67

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 125 PDRAqfMQILQDGIPISaDPIGYPEAYWTPQLESVQRIDFLRGGASLLYGPQ-PAGALNYVTLMPRADKPLGVRQQFimG 203
Cdd:COG1629    68 GGNR--VLVLVDGVPLN-DPSGGDGGLSYIDPEDIERVEVLRGPSSALYGSGaLGGVINIVTKKPKDGKGGEVSASY--G 142

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 204 TDDLISSYTSMDGTIGKLGYHGYFAHRSADGFRQaNSDYETNGGRVKLVYQQDEDTRWIFGLEAFQQENGEPGGLSSA-- 281
Cdd:COG1629   143 SYGTYRASLSLSGGNGKLAYRLSASYRDSDGYRD-NSDSDRYNLRAKLGYQLGDDTRLTLSASYSDSDQDSPGYLTLAal 221

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 282 ----GYAADRNQTVRFNDRFKLSRYAMSIELQHrMSSDTELcikTWAAYYDRWSRRQNGGGFGIVPVGVTTSIDRQEFYN 357
Cdd:COG1629   222 rprgAMDDGTNPYSNDTDDNTRDRYSLSLEYEH-LGDGLKL---SASAYYRYDDTDLDSDFTPTPADGGTLEQTDFDNRT 297

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 358 WGIEPRIRHDYEaWGGKHTISAGMHFYLSHSPTTTKTGATVTSNDGPILRDAQRDIIY--GAVFVENKFTFG-RLTITPG 434
Cdd:COG1629   298 YGLELRLTYDLG-FGGKHTLLVGLDYQRQDLDGSGYPLDLGSGSLPTLTSGADDDGTTtsLALYAQDTYKLTdKLTLTAG 376

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 435 FRMELVNQDMtlqNFAVGAVPETNNSKFDSQPLFGLGLAYDLGSETMLYANISQSYRATTFSQsLIPAAGGTANDAAPSL 514
Cdd:COG1629   377 LRYDYVSYDV---DDTVTGTDSASGSRSYSAFSPSLGLTYQLSPNLSLYASYSRGFRAPTFGE-LYANGTDPYSVGNPDL 452

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 515 ----GWHYELGMRGTP-RPWITWDSAFFLIDLDNK--------FGTTGTALTSVGRSINYGWDGALQFDVIGALdaangt 581
Cdd:COG1629   453 kpetSTNYELGLRYRLlDGRLSLSLALFYSDVDNEilsvplpnDSGFSTYYTNAGKARSYGVELELSYQLTPGL------ 526

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 582 hrgdrlgalNLYANASLLEARLSGGPNN-----GGTPQFAPPYMVRTGVIYSRKSKLKLAFLGTLMARHSGSDTAAAGFD 656
Cdd:COG1629   527 ---------SLNASYSYTDAKFDDDTDGsadldGNRLPGVPPLTANLGLTYEFPGGWSLGLGVRYVGDRYLDDANTQGAP 597

                         650       660       670       680
                  ....*....|....*....|....*....|....*....|....*.
gi 2538030866 657 iPAYTTWDLTAEIPVTQNLKLIGGLNNVFDKQYFARVNAGGIDPAY 702
Cdd:COG1629   598 -GGYTLVDLGAGYRFGDNLTLSLGVDNLFDKKYATSLSVRASNVRG 642
ligand_gated_channel cd01347
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ...
 110-714 9.21e-47

TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.


Pssm-ID: 238657 [Multi-domain]  Cd Length: 635  Bit Score: 176.10  E-value: 9.21e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 110 ETTPLVSLGYRGIGGPDR-------AQFMQILQDGIPISADPIGYPEAYWTPQLESVQRIDFLRGGASLLYGPQ-PAGAL 181
Cdd:cd01347    23 RRIPGVSVTRGGGGGGSTisirgfgPDRTLVLVDGLPLASSNYGRGVDLNTIPPELIERVEVLKGPSSALYGSGaIGGVV 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 182 NYVTlmPRADKPLGVRQQFIMGTDDLISSYTSMDGTIGKLGYHGYFAHRSADGFRQAN-----------SDYETNGGRVK 250
Cdd:cd01347   103 NIIT--KRPTDEFGGSVTAGYGSDNSGSSGGGGFDVSGALADDGAFGARLYGAYRDGDgtidgdgqaddSDEERYNVAGK 180

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 251 LVYQQDEDTRWIFGLEAFQQENGEPGGLSSAGYAA--------DRNQTVRFNDRFKLSRYAMSIELQHRmSSDTELCIKT 322
Cdd:cd01347   181 LDWRPDDDTRLTLDAGYQDQDADGPGGTLPANGTGsslgggpsSNTNGDRDWDYRDRYRKRASLGLEHD-LNDTGWTLRA 259

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 323 WAAY-YDRWSRRQNGGGFGIVPVGVTTSIDRQEFY----NWGIEPRIRHDYEAWGGKHTISAGMHFylshsptttktgat 397
Cdd:cd01347   260 NLSYsYTDNDGDPLILNGGNNAAGGDLGRSGYSSErdttQLGFDAGLNAPFGTGPVAHTLTLGVEY-------------- 325

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 398 vtsndgpilRDAQRDIIYGAVFVENKFTFG-RLTITPGFRMELVNQDMTLQNfavgaVPETNNSKFDSQPLFGLGLAYDL 476
Cdd:cd01347   326 ---------RREELDEKQTALYAQDTIELTdDLTLTLGLRYDHYDQDSKDTI-----AGGTTAKKSYSHWSPSLGLVYKL 391

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 477 GSETMLYANISQSYRA-----TTFSQSLIPAAGGTANDAAPSLGWHYELGMRGTPRPWITWDSAFFLIDLDNK--FGTTG 549
Cdd:cd01347   392 TDGLSLYASYSQGFRApslgeLYGGGSHGGTAAVGNPNLKPEKSKQYELGLKYDPGDGLTLSAALFRIDIKNEivSTPTN 471

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 550 TALTSVGRSIN------YGWDGALQFDVIGALdaangthrgdrlgalNLYANASLL--EARLSGGPNNGGTPQFAPPYMV 621
Cdd:cd01347   472 TGLGLVTVYVNggkariRGVELEASYDLTDGL---------------GLTGSYTYTdtEVKRTDGATTGNRLPGIPKHTA 536

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 622 RTGVIYSRKSKlklAFLGTLMARHSGSDTA-----AAGFDIPAYTTWDLTAEIPVTQNLKLIGGLNNVFDKQYFARVNAG 696
Cdd:cd01347   537 NLGLDYELPDE---GLTAGGGVRYRGKQYAdtangNNTVKVPGYTLVDLSASYQFTKNLTLRLGVNNLFDKDYYTSLSVR 613

                         650       660
                  ....*....|....*....|..
gi 2538030866 697 GID----PAYGRNFYVGGSLTF 714
Cdd:cd01347   614 GSGlygyYGPGRTYYLSVSYKF 635
FepA COG4771
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and ...
 16-677 1.43e-42

Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism];


Pssm-ID: 443803 [Multi-domain]  Cd Length: 612  Bit Score: 163.49  E-value: 1.43e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866  16 AVAAASLLFLAIASHARSQSVSKpklVTELPNVVITADAPEEPQVKIPYlppvegtkiyagkRASII---ELKALPeviS 92
Cdd:COG4771     1 LLLASLLLLLALAAQAADALAED---ATELEEVVVTATRTEQSLSDAPA-------------SVSVItaeEIEKLG---A 61

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866  93 NNYRQAFALTPGLLVAEETTPLVS--LGYRGIGGpdraQFMQILQDGIPISADPIGYPEAY-WTPqLESVQRIDFLRGGA 169
Cdd:COG4771    62 TDLADALRLLPGVSVTRSGGRGGSsgISIRGLGG----DRVLVLIDGVPVNNPALGGGGDLsYIP-PDDIERIEVIRGPA 136

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 170 SLLYGPQP-AGALNYVTLMPRADKPLGVRQQFIMGTDDLISSYTSMDGTIGKLGYHGYFAHRSADGFR-------QANSD 241
Cdd:COG4771   137 SALYGSDAiGGVINIITKKPTDELEGSVSLGYGSNGNGTYSGSLSLGGPGDKLSFLLSGSYRDRDGYLdyrnggfVGNSG 216

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 242 YETNGGRVKLVYQQDEDTRWIFGLEAFQQENGEPGGLSSAGYAADRNQTVRFNDRfklSRYAMSIELQHRMSSDTELcik 321
Cdd:COG4771   217 YERYNLNAKLGYRLSDNHRLSLSGGYSRQDRDGGPPTLGDTEISSDNAGDRDTTT---DRGNYSLRYNGDLGDNLDL--- 290

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 322 twAAYYDRWSRRQNGGGFGivpvGVTTSIDRQEFYNWGIEPRIRHDyeaWGGKHTISAGMHFYLShsptttktgatvTSN 401
Cdd:COG4771   291 --SLYYSRTDRDSTNGSLG----GSTGSFSDSDDTTYGLELDLTYP---LGGNHTLTLGAEYRYD------------DLD 349

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 402 DGPILRDAQRDIIYGAVFVENKFTFG-RLTITPGFRMELVNQDmtlqnfavgavpetnNSKFDSQPLFGLGLAYDLGSET 480
Cdd:COG4771   350 SSSFLGGADASRDTYGLFAQDEWKLTdKLTLTAGLRYDYYSTF---------------GASNYTAFSPRLGLRYDLSDNL 414

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 481 MLYANISQSYRATTFSQSLIPAAGGTANDAAPSLG------WHYELGMRGTPRPW-ITWDSAFFLIDLDNKFGTTGTALT 553
Cdd:COG4771   415 TLRASYGRGFRAPSLAELYGSGTGTPGRYVLGNPDlkpetsDNYELGLEYRLGNGgLSLSLTGFYTDIKDLIVLVPVGPG 494

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 554 S--------VGRSINYGWDGALQFDVigaldaangthrgdrLGALNLYANASLLEARLSGGpNNGGTPQFAPPYMVRTGV 625
Cdd:COG4771   495 PgdvlqyenVGKARTYGLELELKYRL---------------GKGLTLTASYTYLDSKIDDG-DTGEPLPNVPPHKANLGL 558

                         650       660       670       680       690
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2538030866 626 IYSRKSKLKLAFLGTLMARHSGSDTAAAG-FDIPAYTTWDLTAEIPVTQNLKL 677
Cdd:COG4771   559 DYRLPKWWLLLLLTRYYGGRYVTPPSGRLeGYTPGYTLLDLRASYKLTKNLTL 611
TonB-siderophor TIGR01783
TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of ...
 79-714 2.86e-41

TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of TonB-dependent outer membrane siderophore receptors. It has no overlap with TonB receptors known to transport other substances, but is likely incomplete due to lack of characterizations. It is likely that genuine siderophore receptors will be identified which score below the noise cutoff to this model at which point the model should be updated. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273805 [Multi-domain]  Cd Length: 651  Bit Score: 160.27  E-value: 2.86e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866  79 ASIIELKALPEVISNNYRQAFALTPGLLVAEE--TTPLVSLGYRGIGGpdRAQFMQILQDGIPISADPIGYPEAywtpqL 156
Cdd:TIGR01783   6 VSVITRQELEDQQAGSLSEALQRVPGVVVGGSggTTQFGNITIRGFGL--EVDIDNVYLDGVPLLSRGNLAIVD-----P 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 157 ESVQRIDFLRGGASLLYGPQ-PAGALNYVTLMPRaDKPLGVrQQFIMGTDDLISSYTSMDGTIG---KLGYHGYFAHRSA 232
Cdd:TIGR01783  79 AMVERVEVLRGPASLLYGGSaPGGVINIVTKRPQ-DEPKGS-VTFGAGTRSGYRTAFDLGGPLGadgTFRGRLNGARQDG 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 233 DGFRqANSDYETNGGRVKLVYQQDEDTRWIFGLEaFQQENGEP--------GGLSSAGYAADRNQTV---RFNDRFKLSR 301
Cdd:TIGR01783 157 DSFY-DGAGEETRLGATATDWQLDDRTLLRLGAY-YQKERDRGgygglpasGGTSGRDLSSDRYLGTssnRNYDDREYLS 234

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 302 YAMSIELQHRmssdtelciKTWAAYYD-RWSR-------------RQNGGGFGIVPVGVTTSIDRqefynWGIEPRIRHD 367
Cdd:TIGR01783 235 YGLSLEYQFN---------DVWTGKQNlRYSYfdtdsnqvqasgySSDGGLFGRSLTVVNVKQDR-----VQIDAGLDGE 300

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 368 YEAWGGKHTISAG------------MHFYLSHSPTTTKTGATVTSNDGPILRD-AQRDIIY--GAVFVENKFTFGRLTIT 432
Cdd:TIGR01783 301 FETGPIEHDLLLGvsygqrttnrfnNTGYPSDNIYSLTATSSARTDIGDSPKDrALSSTTKalNGVALQRILLADKWTLT 380

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 433 PGFRMELVNQDmtlqnfAVGAVPETNNSKFDSQPLFGLGLAYDLGSETMLYANISQSYRAttfSQSLIPAAGGTANDAAP 512
Cdd:TIGR01783 381 LGGRYDSVDVK------SNNGVAGSTGKRDDSQFTPSLGVAYKPTDDWSLYASYAESFKP---GGYYPKGAGNSGDILEP 451

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 513 SLGWHYELGMRGTPRPWITWDSAFFLIDLDNKF---GTTGTALTSVGRSINYGwdgaLQFDVIGALdaangthrgdrLGA 589
Cdd:TIGR01783 452 EKGKNYELGVRYDLGDSLLATAALFRITKDNQLvqdPVNGTFSVNAGKTRNRG----VELEARGYL-----------TPG 516

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 590 LNLYANASLLEARL---SGGPNNGGTPQFAPPYMVRTGVIYS---RKSKLKLAFLGTLMARHSGSDtaAAGFDIPAYTTW 663
Cdd:TIGR01783 517 LSLSAGYTYTDAEFtedTNGDTQGNTVPFVPKHTASLWASYAppvGDNGLTLGGGVQYTGKAYVDG--GNTGKVPSYTVV 594

                         650       660       670       680       690
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2538030866 664 DLTA--EIPVTQNLKLIGGLNNVFDKQYFARV----NAGGIDPAYGRNFYVGGSLTF 714
Cdd:TIGR01783 595 DLSVryDLTKKKNLTLALNVNNLFDRDYYTSGyrwgPSAYIYPGAPRTVGLSVSYDF 651
FhuE COG4773
Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion ...
 16-714 3.68e-38

Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion transport and metabolism];


Pssm-ID: 443805 [Multi-domain]  Cd Length: 692  Bit Score: 151.20  E-value: 3.68e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866  16 AVAAASLLFLAIASHARSQSVSKPKLVTELPNVVITADApeepqvkipylppvEGTKIYAGKRASI-----IELKALPEV 90
Cdd:COG4773     3 ALLAGSGLAAAAAGALAQAAAAAAAEATTLPEVTVTGTA--------------EGTGGYTAKSSSTatkldTPLRETPQS 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866  91 IS------------NNYRQAFALTPGllvaeettplVSLGYRGigGPDRAQFM-------QILQDGIPISADPIGYPEay 151
Cdd:COG4773    69 VSvvtrqliedqgaTTLDDALRNVPG----------VTVSSYD--GGGRDSFSirgfsidNYLRDGLPLGGFGGGQPD-- 134

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 152 wtpqLESVQRIDFLRGGASLLYGP-QPAGALNYVTLMPRADKPLGVRQQFimGTDDLISSYTSMDGTI---GKLGYHGYF 227
Cdd:COG4773   135 ----TANLERVEVLKGPAGLLYGAgSPGGLVNLVTKRPTAEPQGEVSLSA--GSWDTYRATADVGGPLnedGTLRYRLNA 208

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 228 AHRSADGFRQaNSDYETNGGRVKLVYQQDEDTRWIFGLEAFQQE-NGEPGGLSSAGYAADRNQTVRFN---DRFKLSRYA 303
Cdd:COG4773   209 AYEDGDSFRD-GVDNRRTLIAPSLDWDLTDDTTLTLGAEYQDDDsTGDRGFLPLDGTLLDLPRSTNLGepwDYYDTETTT 287

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 304 MSIELQHRMSSDTELcikTWAAYYDRWSRRQNGGGFGIVPVGVTTSIDR------QEFYNWGIEPRIRHDYEAWGGKHTI 377
Cdd:COG4773   288 LFAELEHRFNDDWSL---RANARYSDSDRDGRSAYAYGAPDAATGTLTRyasardGDSRSDSLDANLNGKFETGGLEHTL 364

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 378 SAGMHFYLSHSPTTTKTGAT---------VTSNDGPILRDAQRDIIYGAVFVENKFTFG-RLTITPGFRMELVNQDMTlq 447
Cdd:COG4773   365 LVGADYSRYDSDSDSATAGTiniynpvygNLPEPDFDASDTDTTTRQTGLYAQDQISLTdRLSLLLGGRYDWYETDST-- 442

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 448 NFAVGAVPETNNSKFdsqpLFGLGLAYDLGSETMLYANISQSYRAttfsQSLIPAAGGTAndaAPSLGWHYELGMRGTPR 527
Cdd:COG4773   443 NRLGGSTTSYDDSAF----TPRAGLVYDLTPGLSLYASYSESFEP----QSGADNNGNPL---DPETGKQYEAGVKGELF 511

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 528 PW-ITWDSAFFLIDLDNKF---GTTGTALTSVGRSINYGWDgalqFDVIGALdaangthrgdrLGALNLYANASLLEARL 603
Cdd:COG4773   512 DGrLNATLAVFDITQKNVAttdPDNPNFYVQVGEVRSRGVE----LELSGEL-----------TPGLNLIAGYTYTDAKI 576

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 604 SGGPN--NGGTPQFAPPYMVRTGVIYsRKSKLKLAFLG-TLMARHSGS--DTAAAGFDIPAYTTWDLTAEIPVTQNLKLI 678
Cdd:COG4773   577 TKDADalEGKRLTNVPRHTASLWTTY-RFPSGALKGLGlGGGVRYVGEryGDAANTFTLPSYTLVDAGARYDLGKNWTLQ 655

                         730       740       750
                  ....*....|....*....|....*....|....*..
gi 2538030866 679 GGLNNVFDKQYFARV-NAGGIDPAYGRNFYVGGSLTF 714
Cdd:COG4773   656 LNVNNLFDKKYYASSgSRGYVYYGAPRNVRLSLSYKF 692
Fiu COG4774
Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism];
111-714 4.54e-36

Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism];


Pssm-ID: 443806 [Multi-domain]  Cd Length: 639  Bit Score: 144.64  E-value: 4.54e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 111 TTPLVSLGYRGIGGPDR------AQFMQILQDGIPISADpigypeayWTPQLESVQRIDFLRGGASLLYGP-QPAGALNY 183
Cdd:COG4774    35 NVPGVTFGAGEGGNGDSfsirgfSASGDIYVDGLRDPGQ--------YRRDTFNLERVEVLKGPASVLYGRgSPGGVINL 106

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 184 VTLMPRADKPLGVRQQFimGTDDLISSYTSMDGTIG-KLGYHGYFAHRSADGFRQaNSDYETNGGRVKLVYQQDEDTRWI 262
Cdd:COG4774   107 VTKRPTDEPFTEVTLTY--GSDGQRRATLDVNGPLGdDLAYRLNGMYRDSDSYRD-GVDNDRWGIAPSLTWRLGDRTRLT 183

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 263 FGLEAFQQENGEPGGL--SSAGYAADRNQTVRF---NDRFKLSRYAMSIELQHRMSSDTELciKTWAAYYDRWSRRQNGG 337
Cdd:COG4774   184 LDYEYQDDDRTPDYGVpaVANGRPVDVDRSTFYgqpDDYSDSETDSATLRLEHDFNDNWTL--RNALRYSDYDRDYRNTY 261

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 338 GFGIVP---VGVTTSIDRQEFYNWGIEPRIRHDYEAWGGKHTISAGMHFYL--SHSPTTTKTGATVTSN------DGPIL 406
Cdd:COG4774   262 PTGGNAtgtVTRSAYRRDQDNDTLSNQTDLTGKFDTGGVKHTLLAGVEYSRedSDNARYSGGGTAPTVNlynpvyGAPVT 341

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 407 ------RDAQRDIIYGAVFVENKFTFG-RLTITPGFRMELVNQDMTlqNFAVGAvpeTNNSKFDSQPLFGLGLAYDLGSE 479
Cdd:COG4774   342 gptlggADNDSRTDTTGLYLQDTISLTdRWSLLAGLRYDRFDTDYT--DRTTGA---TTSSYDDSAFSPRAGLVYKPTPN 416

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 480 TMLYANISQSYRATTFSqsliPAAGGTANDAAPSLGWHYELGMRGTP-RPWITWDSAFFLIDLDNKF---GTTGTALTSV 555
Cdd:COG4774   417 LSLYASYSTSFNPGGGA----PSLSNAGQALDPEKSRQYEVGVKWDLlDGRLSLTAALFRIEKTNVRttdPANPGVYVQT 492

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 556 GRSINYGwdgaLQFDVIGALdaangthrgdrLGALNLYANASLLEARL---SGGPNNGGTPQFAPPYMVRTGVIYS-RKS 631
Cdd:COG4774   493 GEQRSRG----VELEATGEL-----------TPGWSVLAGYTYLDAEItksANAANVGNRLPNVPRHSASLWTTYDlPLP 557

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 632 KLKLAfLGtlmARHSGS--DTAAAGFDIPAYTTWDLTAEIPVTQNLKLIGGLNNVFDKQYFARVNAGG-IDPAYGRNFYV 708
Cdd:COG4774   558 GLTLG-GG---VRYVGSryADAANTVKLPSYTRFDAGASYRLNKNLTLRLNVNNLTDKRYYASAYGSGyVTPGAPRTVLL 633


                  ....*.
gi 2538030866 709 GGSLTF 714
Cdd:COG4774   634 SASYRF 639
TonB_dep_Rec pfam00593
TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
 272-713 6.70e-30

TonB dependent receptor; This model now only covers the conserved part of the barrel structure.


Pssm-ID: 395474 [Multi-domain]  Cd Length: 475  Bit Score: 124.11  E-value: 6.70e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 272 NGEPGGLSSAGYAADRNQTVRFNDRFKLSRYAMSIELQHRMSSDTELCIKTWAAYYDRWSRR--QNGGGFGIVPVGVTTS 349
Cdd:pfam00593  33 TLDGYGNDGGYLGDRPLYYGRDYSDTDRKRLSLGYDYDLGDGLSWLSTLRLGLRYSSLDGDYtsNSSGLSGAGDYLSDDR 112

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 350 IDRQEFYNWGIEPRIRHDYEAWGGKHTISAGMHFYLSHSPTTTKTGATVTSNDGPILRDAQRdiiyGAVFVENKFTF-GR 428
Cdd:pfam00593 113 LYGLYGLDGDLELSLDLSHDLLLGVELRTAGLDYRRLDDDAYDPYDPANPSSSSYSDTTTDS----YGLYLQDNIKLtDR 188

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 429 LTITPGFRMELVNQDMTLQNfavgaVPETNNSKFDSQPLFGLGLAYDLGSETMLYANISQSYRATTFSQ---SLIPAAGG 505
Cdd:pfam00593 189 LTLTLGLRYDHYSTDGDDGN-----GGGDNFSRSYSAFSPRLGLVYKPTDNLSLYASYSRGFRAPSLGElygSGSGGGGG 263

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 506 TANDAAPSL----GWHYELGMRGTPRpWITWDSAFFLIDLDNK---------FGTTGTALTSVGRSINYGWDGALQfdvi 572
Cdd:pfam00593 264 AVAGGNPDLkpetSDNYELGLKYDDG-RLSLSLALFYIDIKNLitsdpdgpgLGGTVYTYTNVGKARIRGVELELS---- 338

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 573 galdaangthrGDRLGALNLYANASLLEARLSGGPNNGGTP-QFAPPYMVRTGVIYSrksKLKLAFLGTLMARHSGSDT- 650
Cdd:pfam00593 339 -----------GRLWGLGLSGGGYTYTDADDDADADDTGNPlPNVPRHTANLGLTYD---FPLGGWGARLGARYVGSGEr 404

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2538030866 651 ----AAAGFDIPAYTTWDLTAEIPVTQNLKLIGGLNNVFDKQYFARVNAGGID----PAYGRNFYVGGSLT 713
Cdd:pfam00593 405 rygdAANTFKTPGYTLVDLSAGYRLNKNLTLRLGVNNLFDKYYKRYYSSGGGNlggyPGPGRTFYLGLSYK 475
BtuB COG4206
Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism];
48-339 5.56e-13

Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism];


Pssm-ID: 443355 [Multi-domain]  Cd Length: 276  Bit Score: 69.90  E-value: 5.56e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866  48 VVITADAPEEPQVKIPYlpPVegtkiyagkraSIIELKALPEVISNNYRQAFALTPGLLVAEETTP--LVSLGYRGIGgp 125
Cdd:COG4206     1 VVVTATRLEQSKSDLTG--SV-----------TVIDAEELERSGATSLADALRRVPGVQVSSSGGPgsAASISIRGLG-- 65

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 126 drAQFMQILQDGIPISADPIGYPEAYWTPqLESVQRIDFLRGGASLLYGPQPA-GALNYVTLMPRADKPLGVRQQFimGT 204
Cdd:COG4206    66 --SNQTLVLIDGVPLNDPSLGGVDLSLIP-PDDIERIEVLKGAASALYGSDAIgGVINITTKKGKKGFKGSVSASY--GS 140

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 205 DDLISSYTSMDGTIGKLGYHGYFAHRSADGFRQA------NSDYETNGGRVKLVYQQDEDTRWIFGLEAFQQENGEPGgl 278
Cdd:COG4206   141 FGTRRLSASLSGGAGKFSYSLSASYRRSDGYRYNdpdlrnNDGYENTSLNARLGYKLGDNGSLSLSGGYSDSERGYPG-- 218

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2538030866 279 ssaGYAADRNQTVRFNDRFKLSRYAMSIELQHRMSSDTELCIKTWAAYYDRWSRRQNGGGF 339
Cdd:COG4206   219 ---AVGSDRNLRLSLSLEYKLSDGWSLLLLAYYYYDRDYEDGGGDSAGTSNTDGARAGLSY 276
TonB-hemin TIGR01785
TonB-dependent heme/hemoglobin receptor family protein; This model represents the ...
 80-714 6.74e-13

TonB-dependent heme/hemoglobin receptor family protein; This model represents the TonB-dependent outer membrane heme/hemoglobin receptor/transporter found in bacteria which live in contact with animals (which contain hemoglobin or other heme-bearing globins) or legumes (which contain leghemoglobin). Some species having hits to this model such as Nostoc, Caulobacter and Chlorobium do not have an obvious source of hemoglobin-like proteins in their biological niche and so the possibility exists that they act on some other substance. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273807 [Multi-domain]  Cd Length: 665  Bit Score: 72.04  E-value: 6.74e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866  80 SIIELKALPEVISNNYRQAFALTPGLLVAE-ETTPLVSLGYRGIGGPDRAqfmqILQDGIPISADPIG--YPEAYWTPQL 156
Cdd:TIGR01785  23 SVISGEQIESKQANNLADALNTVPGVDVTGgGRPPGQSINIRGLQDNRVL----VVVDGARQNYQRGGahNGSLFVDPEL 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 157 esVQRIDFLRGGASLLYGpqpAGAL----NYVTLMP----RADKPLGVRQQFIMGTDDL------ISSYTSMDGT--IGK 220
Cdd:TIGR01785  99 --LKRIEIVKGPSSSLYG---SGALggvvAFRTKDAadllRPGQLFGGLAKLSYGSNNNsfggsvAVAGRLDDNLdaLVA 173

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 221 LGYHGYFAHRSADGFRQANSDYETNGGRVKLVYQQDEDTRwiFGLEAFQQENGEPGGLSSAGyaadrNQTVRFNDRFKL- 299
Cdd:TIGR01785 174 ATYRDGGNYRNGNKEEATNSAYVQKNLLAKLGWQLDDAQR--LEFSYFTTEGSLDEAQNSGP-----GTEYVLGSSSTLl 246

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 300 --SRYAMSIELQHRMSSDTELCIKTWAAYY--DRWSRRQNGGGfgivpvGVTTSIDRQeFYNWGI--EPRIRHDYEAWgg 373
Cdd:TIGR01785 247 asSTRDRSATLTYNWTPEDNPWLDATASLYynRTENDNDRSAR------GVGREEGYQ-YTTYGAtlQNTSRFDVASW-- 317

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 374 kHTISAGMHFYLSHSPTTTKTGATVTSNDGPilrDAQRDIIYGAVFVENKFTF--GRLTITPGFRMElvNQDMTLQNFAV 451
Cdd:TIGR01785 318 -STLTYGVDWMKDKRRTESFDPNSVTTIVPN---PPSAKEYFFGLFLQDNIPLldDRLTLSAGLRYD--HYKLSPKTTAD 391

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 452 GAVPETNNSKFDSQplfgLGLAYDLGSETMLYANISQSYRATTFSQSLI---PAAGGTANDAAP--------SLGWhyEL 520
Cdd:TIGR01785 392 TEAVDRSYSRWSPS----LGLSYKPVDWLTLYASYSQGFRAPSIDELYGtgdHPGTPGGYTFAPnpnlkpetSKTW--EL 465

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 521 GMRgtprpwITWDSAFF-LIDLDNK---FGTTGTALTSVGRSInYGWDGALQFDVIGALDAANGTHRGdrLGALNLYaNA 596
Cdd:TIGR01785 466 GAN------LSFDNLLLdNDQLQFKvayFYNDVKDFIDLTIGV-TDNVTAGMNNITQYVNIDGARIRG--IEASASY-DA 535

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 597 SLLEARLSG----GPNNGGTPQFA--PPYMVRTGVIYSR-KSKLKLAFLGTLMARHSGSDTAAAG-----FDIPAYTTWD 664
Cdd:TIGR01785 536 GLWATGLSYgytiGKDQNTNQWLSniPPLKLVVTVGYRFpDRRLDLGAKAAYYERQSESPTTEDVaanglLTTPGYTVVD 615

                         650       660       670       680       690
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2538030866 665 LTAEIPVTQ--NLKLIGGLNNVFDKQYFARVNAGGIDPayGRNFYVGGSLTF 714
Cdd:TIGR01785 616 LYATYQPNAvkGLTVRFGVNNLTDRKYTPAQSVPGAGP--GRNFKGSVKYQF 665
PRK13513 PRK13513
ligand-gated channel protein;
25-714 5.03e-07

ligand-gated channel protein;


Pssm-ID: 184104 [Multi-domain]  Cd Length: 659  Bit Score: 53.23  E-value: 5.03e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866  25 LAIASHARSQSVSKPKLVTELPN--VVITADAPEEpqvKIPYLPpvegtkiyagkrASI-------IELKALPEVISnny 95
Cdd:PRK13513   13 LVIAAAISSQAYAAEKTNTATPTdtMVVTASGFQQ---RIQDAP------------ASIsvvtreqLENKAYRDVTD--- 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866  96 rqAFALTPGLLVAE-ETTPLVSLgyRGIGgpdrAQFMQILQDGIPIS-------ADPIGYpEAYWTPQLESVQRIDFLRG 167
Cdd:PRK13513   75 --ALKDVPGVVVTGgGSTSDISI--RGMA----AKYTLILVDGKRVDtrstrpnSDGSGI-EQGWLPPLAAIERIEVVRG 145

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 168 GASLLYGPQP-AGALNYVTLMP--------RADKPLGVRQQfiMGTDDLISSYTS---MDGTIGkLGYHGYFAHRSADGF 235
Cdd:PRK13513  146 PMSSLYGSDAmGGVINIITRKVqkewhgslRADATLQEDSK--SGDIFQTNAYASgplIDGLLG-LKVSGLLSHRSEDKI 222

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 236 RQANSDYETNGGRVKLVYQQDEDTRWIFGLEAFQQENGepgglSSAGYAADRNQTVRFNdRFKLSRYAMsielqhrmssd 315
Cdd:PRK13513  223 IDGYNEQRMRNGTATFSLTPDDNNEFDFEIGRYVQDRN-----STPGRTLALNGTNSDT-QYDRNNYAI----------- 285

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 316 telcikTWAAYYDrwsrrqngggFGivpvGVTTSIDRQEFYNWGIEprIRHDYEAWGGKHTISAGMHfYLSHSPTTTKTG 395
Cdd:PRK13513  286 ------THNGYYD----------FG----NSTSYIQRDETRNPSRQ--MKSVDTIFNTQTSFLLDDH-TLSLGGQYRYEE 342

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 396 ATVTSNDGPILRDAQRDIIYG-AVFVENKFTF-GRLTITPGFRMelvNQDmtlQNFAVGAVPEtnnskfdsqpLFGLgla 473
Cdd:PRK13513  343 LYDKGNQLPSASDLNKLTRWSwALFAEDEWQMtNDFALTGGIRM---DQD---QNYGTHWTPR----------LYGV--- 403

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 474 YDLGSETMLYANISQSYRATTFSQSLIP----AAGGTAN-------DAAPSLGWHYELGmrgtprpwITWDS-------- 534
Cdd:PRK13513  404 WHLADQWTLKGGVSTGYRSPDLRQATDNwgqlTGGGGLPalilgnsDLKPEKSISQEIG--------ILWDNqenlnasv 475

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 535 AFFLIDLDNKfgttgtaLTSVGRSINYGWDGALQ-----FDVIGA---LDAAN-----GTHRGDRLGALNLYANASLLEA 601
Cdd:PRK13513  476 TLFNTDFKDK-------ITEVRNCDTTNTDGQCVfnginYDFISDrinVDKANmrgveATFNWDINQAWSLATNYTFTQS 548

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 602 RLSGGPNNGGTPQFAPPYMVRTGVIYSRKSKL----KLAFLGTLMARHSGSDTAAAgfdIPAYTTWDLTAEIPVTQNLKL 677
Cdd:PRK13513  549 EQKSGAFAGQPLNQMPKHMANATLNWQTTEDFatwiRINYRGKTSEYLNRTSMGSG---TPSYTFVDLGASYQLTKELRL 625

                         730       740       750
                  ....*....|....*....|....*....|....*..
gi 2538030866 678 IGGLNNVFDKQYFARVNAGGIDpayGRNFYVGGSLTF 714
Cdd:PRK13513  626 MGGVYNLLDKRVDIDVNDKVLD---GRRYMVGASYDF 659
PRK10044 PRK10044
ferrichrome outer membrane transporter; Provisional
 96-691 1.64e-06

ferrichrome outer membrane transporter; Provisional


Pssm-ID: 236643 [Multi-domain]  Cd Length: 727  Bit Score: 51.68  E-value: 1.64e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866  96 RQAFALTPGLLV----AEETTPLVSLgyRGIGGPDRAQFMQIlqDGIPISADpiGYPEAYWTPQLesVQRIDFLRGGASL 171
Cdd:PRK10044  100 KEALSYTPGVSVgtrgASNTYDHLII--RGFAASGQSQNNYL--DGLKLQGN--FYNDAVIDPYM--LERAELMRGPVSV 171

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 172 LYG-PQPAGALNYVTLMPRADkPLgvRQ-QFIMGTDDLISSYTSMDGTI---GKLGYHGYFAHRSADGfRQANSDYETNG 246
Cdd:PRK10044  172 LYGkSNPGGLLNMVSKRPTTE-PL--KEvQFKMGTDNLFQTGFDFSDALdddGVYSYRLTGLARSANA-QQKGSEEQRYA 247

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 247 GRVKLVYQQDEDTRWIFgLEAFQQE-----------------------------NGEPGGLSS-----AGYAADR----N 288
Cdd:PRK10044  248 IAPSFTWRPDDKTNFTF-LSYFQNEpetgyygwlpkegtveplpngkrlptdfnEGAKNNTYSrnekmVGYSFDHefndT 326

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 289 QTVRFNDRFK---------------------LSR-YAMSIELQHRMSSDTELciktwaayydrwsrrQNGGGFGIVPVGV 346
Cdd:PRK10044  327 FTVRQNLRYAenktsqrsvygygvcsdkghyLNRgYVVDDEKLQNFSVDTQL---------------QSKFATGDVDHTL 391

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 347 TTSIDRQefynwgiepRIRHDYEAWGGkhtISAGMHFYLSHSPTTTKTGATVTSNDGPILRDAQRDIIYgavfVENKFTF 426
Cdd:PRK10044  392 LTGVDFM---------RMRNDINAWFG---YADSVPLLNLYGPVNTDFDFNANSGPYQILNKQKQTGLY----VQDQAEW 455

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 427 GRLTITPGFRMELVNQDMTlqNFAVGAVPETNNSKFDSQPlfglGLAYdlgsetmLYANISQSYraTTFSQSLIPAAGGT 506
Cdd:PRK10044  456 DKWLVTLGGRYDWADQSSL--NRVNGTTDKRDDKQFTWRG----GVNY-------LFDNGITPY--FSYSESFEPSSGTG 520

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 507 A--NDAAPSLGWHYELGMRGTP--RPWITWDSAFFLIDLDNKFGTTGTALTSV-GRSINygwDGALQFDVIGALDAangt 581
Cdd:PRK10044  521 KdgNIFAPSKGKQYEAGVKYVPkdRPIVVTGAVYQLTKTNNLTADPENSFFSVqGGEIR---ARGVELEAKAALSA---- 593

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 582 hrgdrlgALNLYANASLLEARLSGGPN-NGGTPQFAPPYMVRTGVIYS-RKSKLKLAFLGTlMARHSGSDT--AAAGFDI 657
Cdd:PRK10044  594 -------NVNVTGSYTYTDAEYTTDTTyKGNTPAQVPKHMASLWADYTfFDGPLSGLTLGT-GGRYTGSSYgdPANSFKV 665

                         650       660       670       680
                  ....*....|....*....|....*....|....*....|..
gi 2538030866 658 PAYTTWDLTaeipVTQNLKLIG--------GLNNVFDKQYFA 691
Cdd:PRK10044  666 GSYTVVDAL----VKYDLARFGmagssvalNVNNLFDREYVA 703
Plug pfam07715
TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently ...
 80-179 1.66e-06

TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently folding subunit of the TonB-dependent receptors. It acts as the channel gate, blocking the pore until the channel is bound by ligand. At this point it under goes conformational changes opens the channel.


Pssm-ID: 462243 [Multi-domain]  Cd Length: 107  Bit Score: 47.26  E-value: 1.66e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866  80 SIIELKALPEVISNNYRQAFALTPGLLVAEETTPLVS-LGYRGIGGpdraQFMQILQDGIPISADPIGYPEAYWTPqLES 158
Cdd:pfam07715  10 SVVTAEDIEDQGATNLADALRGVPGVSVSSGGGGGGSsISIRGFGS----NRVLVLVDGVPLNSGGGGSVDLNSID-PED 84

                          90       100
                  ....*....|....*....|.
gi 2538030866 159 VQRIDFLRGGASLLYGPQPAG 179
Cdd:pfam07715  85 IERVEVLKGPASALYGSGAIG 105
PRK13528 PRK13528
outer membrane receptor FepA; Provisional
 407-714 8.13e-06

outer membrane receptor FepA; Provisional


Pssm-ID: 237413 [Multi-domain]  Cd Length: 727  Bit Score: 49.37  E-value: 8.13e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 407 RDAQRDIIYGAVFVENKFTFG-RLTITPGFRMElvnqdmtlqnfavgavpetNNSKFDSQPLFGLGLAYDLGSETMLYAN 485
Cdd:PRK13528  416 RSSKNKSEISALYVEDNIEPVpGTNLIPGLRFD-------------------YHSEFGSNWSPSLNLSQELGDYFKVKAG 476

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 486 ISQSYRATTFSQS-------------LIPAAGG----TANDA-APSLGWHYELGMRGTPRPWITwDSAFFLIDLDNKF-- 545
Cdd:PRK13528  477 IARAFKAPNLYQSsegyllysrgngcPKDITSGgcylVGNKNlDPEISVNKEIGLEFTVDDYHA-SVTYFRNDYQNKIva 555

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 546 GTTGTALTS----------VGRSINYGWDGALQFDVIGAldaangthrgdrlgALNLYANAS-LLEarlSGGPNNGGTPQ 614
Cdd:PRK13528  556 GDDVIGRTAsgayilqwqnGGKAVVEGLEGNLLVPLMKD--------------RLNWNTNATyMIT---SEQKDTGNPLS 618

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 615 FAPPYMVRTGVIYSRKSKLKLAFLGTLMARHSGSDTA---------AAGFDIPAYTTWDLTAEIPVTQNLKLIGGLNNVF 685
Cdd:PRK13528  619 VIPKYTINSTLDWQITQALSANVNWTLYGKQKPRTHAesrseetggLSGKELGAYSLVGVNVNYDINKNLRLNVGVSNLF 698

                         330       340       350
                  ....*....|....*....|....*....|..
gi 2538030866 686 DKQYFaRVNAGGI---DPayGRNFYVGGSLTF 714
Cdd:PRK13528  699 DKQIY-REGEGANtynEP--GRAYYAGVTASF 727
PRK13524 PRK13524
FepA family TonB-dependent siderophore receptor;
417-714 1.04e-05

FepA family TonB-dependent siderophore receptor;


Pssm-ID: 237410 [Multi-domain]  Cd Length: 744  Bit Score: 48.87  E-value: 1.04e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 417 AVFVENKFTFG-RLTITPGFRmelvnqdmtlqnfavgavpetnnskFDSQPLFG------LGLAYDLGSETMLYANISQS 489
Cdd:PRK13524  434 SLFAEDNMELTdSTMLTPGLR-------------------------FDHHSIVGnnwspsLNLSQGLGDDFTLKMGIARA 488

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 490 YRATTFSQS----LI-------PAAGGTA------NDAAPSLGWHYELGM---RGTPRPWITWdsafFLIDLDNKF--GT 547
Cdd:PRK13524  489 YKAPNLYQTnpnyILyskgqgcYASAGNGcylqgnDDLKAETSVNKEIGLefkRDGWLAGLTW----FRNDYRNKIeaGY 564

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 548 TGTALTSVGRSINY-----------GWDGALQFDVIGALDAANG---------THRGDRLgalnlyanaSLLearlsggp 607
Cdd:PRK13524  565 VPVGTNSVGKTDIYqwenvpkavveGLEGTLNVPVSETVNWTNNltymlqsknKTTGDPL---------SII-------- 627

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 608 nnggtpqfaPPYMVRTGVIYSRKSKLKLAFLGTLMAR--------HSGSDTAAAGFDIPAYTTWDLTAEIPVTQNLKLIG 679
Cdd:PRK13524  628 ---------PEYTLNSTLSWQATEDLSLQSTFTWYGKqkpkkynyKGQPVTGSATKEVSPYSIVGLSATYDVTKNVSLTG 698

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*.
gi 2538030866 680 GLNNVFDKQYFARVNAGGIDPAY-----------GRNFYVGGSLTF 714
Cdd:PRK13524  699 GVDNLFDKRLWREGNAQTTGDLIagagaytynepGRTYYMSLNTHF 744
btuB PRK10641
TonB-dependent vitamin B12 receptor BtuB;
658-714 3.85e-04

TonB-dependent vitamin B12 receptor BtuB;


Pssm-ID: 236730 [Multi-domain]  Cd Length: 614  Bit Score: 43.83  E-value: 3.85e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2538030866 658 PAYTTWDLTAEIPVTQNLKLIGGLNNVFDKQYfarvnaggiDPAY-----GRNFYVGGSLTF 714
Cdd:PRK10641  562 GGVSLWDLAVSYPVTSHLTVRGKIANLFDKDY---------ETVYgyqtaGREYTLSGSYTF 614
PRK13483 PRK13483
ligand-gated channel protein;
7-185 5.03e-04

ligand-gated channel protein;


Pssm-ID: 184080 [Multi-domain]  Cd Length: 660  Bit Score: 43.23  E-value: 5.03e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866   7 SKFPLSGGPAVAAASLLFLAiasHARSQSVSKPKLVTelpnVVITADAPEEPQVKIPylppvegtkiyagkrASI--IEL 84
Cdd:PRK13483    2 KKYLAQVISALCLLPAVFVT---HALAQAAPDKTMET----VVVTASGYEQQIRDAP---------------ASIsvITR 59

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866  85 KALPEVISNNYRQAFALTPGLLV--AEETTPlVSLgyRGIGgpdrAQFMQILQDGIPIS-------ADPIGYpEAYWTPQ 155
Cdd:PRK13483   60 EDLENRFYRDLTDALLDVPGVVVtgGGDRTD-ISL--RGMG----SQYTLILVDGKRQSsretrpnSDGPGV-EQAWTPP 131

                         170       180       190
                  ....*....|....*....|....*....|.
gi 2538030866 156 LESVQRIDFLRGGASLLYGPQP-AGALNYVT 185
Cdd:PRK13483  132 LAAIERIEVIRGPMSSLYGSDAiGGVINIIT 162
PRK10003 PRK10003
ferric-rhodotorulic acid outer membrane transporter; Provisional
 511-714 1.99e-03

ferric-rhodotorulic acid outer membrane transporter; Provisional


Pssm-ID: 236640 [Multi-domain]  Cd Length: 729  Bit Score: 41.39  E-value: 1.99e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 511 APSLGWHYELGMRGTprpW----ITWDSAFFLIDLDNKFGTTGTALT-SVGRSINYGWDG----ALQFDVIGAL-DAANG 580
Cdd:PRK10003  530 APITGNNYELGLKSD---WmnsrLTTTLAIFRIEQDNVAQSTGTPIPgSNGETAYKAVDGtvskGVEFELNGAItDNWQL 606

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538030866 581 THRGDRLGALNLYANA-------------------SLLEARLSGGPN--NGGTPQFAPPYmvrtgviysrksklklaflG 639
Cdd:PRK10003  607 TFGATRYIAEDNEGNAvnpnlprttvklftryrlpVMPELTVGGGVNwqNRVYTDTVTPY-------------------G 667

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2538030866 640 TLMARHSGsdtaaagfdipaYTTWDLTAEIPVTQNLKLIGGLNNVFDKQYFARVNAGGIdpaYG--RNFYVGGSLTF 714
Cdd:PRK10003  668 TFRAEQGS------------YALVDLFTRYQVTKNFSVQGNVNNLFDKTYDTNVEGSIV---YGapRNFSITATYQF 729
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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