|
Name |
Accession |
Description |
Interval |
E-value |
| PykF |
COG0469 |
Pyruvate kinase [Carbohydrate transport and metabolism]; Pyruvate kinase is part of the ... |
4-475 |
0e+00 |
|
Pyruvate kinase [Carbohydrate transport and metabolism]; Pyruvate kinase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 440237 [Multi-domain] Cd Length: 471 Bit Score: 775.75 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 4 MRKTKIICTLGPAVDSEEMIRKLILAGMNAARFNFSHGTHESHLAQLTKLKRVRDELGIPVAAIMDTKGPEIRIKTFKDG 83
Cdd:COG0469 2 MRRTKIVATLGPASDSPEVLRKLIEAGMDVARLNFSHGDHEEHRERIELIREAAKELGRPVAILLDLQGPKIRTGKFKEG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 84 RIELKKDDIFTLTTADCEGDATRVSVTYANLHNEVVPGNHILVDDGLIDLLVQEIKGQEIVCTVENGGPLSNNKSINIPD 163
Cdd:COG0469 82 PVELKKGDTFTLTTDDVEGDAERVSVTYPELPEDVKPGDRILLDDGKIELRVEEVEGDEVVCEVVNGGVLSSRKGVNLPG 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 164 VHILLPSLTEKDKEDLKFAVENDFDFIAASFVRKASDVEDIRAWLNECGGeKIRIISKIENREGVDNLAEIIAASDGVMV 243
Cdd:COG0469 162 VGLSLPALTEKDREDLKFALELGVDFIALSFVRSAEDVLEARELLEEAGG-RAPIIAKIEKPEAVENLDEIIEASDGIMV 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 244 ARGDLGVEIPAQEVPILQKKMIKATTMAGKPVITATQMLDSMIRNPRPTRAEVSDVANAVFDGTSCVMLSGETASGKYPI 323
Cdd:COG0469 241 ARGDLGVEIPLEEVPLIQKRIIRKARRAGKPVITATQMLESMIENPRPTRAEVSDVANAVLDGTDAVMLSGETAVGKYPV 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 324 EAVEAMVSTVKAAESAINYWGRFREHSLQPGvSSINDAITHTCCMTAMDLNATAILAPTESGYTAKVISRFRPACPIVAV 403
Cdd:COG0469 321 EAVETMARIAEEAEKSLDYRRILDRLRDEPE-RTITDAIARAAVELAEDLGAKAIVAFTESGSTARRISRYRPKVPILAL 399
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2538191712 404 CQSEKVRRQLAISWGVHSYLTGFVDSTDRLFSMSVEVARKEGAVKCGDTVVITAGVPIGKSGTTNLIKAQVV 475
Cdd:COG0469 400 TPNERTARRLALVWGVYPVLVDDVESTDEMIEEAVEALLEEGLVKPGDLVVITAGVPVGVPGTTNTLKVHRV 471
|
|
| PRK05826 |
PRK05826 |
pyruvate kinase; Provisional |
4-465 |
0e+00 |
|
pyruvate kinase; Provisional
Pssm-ID: 235619 [Multi-domain] Cd Length: 465 Bit Score: 657.61 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 4 MRKTKIICTLGPAVDSEEMIRKLILAGMNAARFNFSHGTHESHLAQLTKLKRVRDELGIPVAAIMDTKGPEIRIKTFKDG 83
Cdd:PRK05826 3 LRRTKIVATLGPASDSPENLEKLIEAGVNVVRLNFSHGSHEEHGKRAALVREIAAKLGRPVAILLDLKGPKIRVGKFKEG 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 84 RIELKKDDIFTLTTADC-EGDATRVSVTYANLHNEVVPGNHILVDDGLIDLLVQEIKGQEIVCTVENGGPLSNNKSINIP 162
Cdd:PRK05826 83 KITLKTGDKFTLDTDQKeEGDKERVGVDYKGLPKDVKPGDILLLDDGKLQLKVVEVDGDEVETEVKNGGPLSNNKGINIP 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 163 DVHILLPSLTEKDKEDLKFAVENDFDFIAASFVRKASDVEDIRAWLNECGGEKIRIISKIENREGVDNLAEIIAASDGVM 242
Cdd:PRK05826 163 GGGLSLPALTEKDKADIKFAAEQGVDYIAVSFVRSAEDVEEARRLLREAGCPHAKIIAKIERAEAVDNIDEIIEASDGIM 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 243 VARGDLGVEIPAQEVPILQKKMIKATTMAGKPVITATQMLDSMIRNPRPTRAEVSDVANAVFDGTSCVMLSGETASGKYP 322
Cdd:PRK05826 243 VARGDLGVEIPDEEVPGLQKKIIRKAREAGKPVITATQMLESMIENPRPTRAEVSDVANAVLDGTDAVMLSGETAAGKYP 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 323 IEAVEAMVSTVKAAESA--INYWGRFREHSLqpgvSSINDAITHTCCMTAMDLN-ATAILAPTESGYTAKVISRFRPACP 399
Cdd:PRK05826 323 VEAVEAMARICKGAEKEfsINLSKHRLDRQF----DRIDEAIAMSAMYAANHLKgVKAIVALTESGRTARLISRFRPGAP 398
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2538191712 400 IVAVCQSEKVRRQLAISWGVHSYLTGFVDSTDRLFSMSVEVARKEGAVKCGDTVVITAGVPIGKSG 465
Cdd:PRK05826 399 IFAVTRDEKTQRRLALYRGVYPVLFDSAADTDDAAEEALRLLLEKGLVESGDLVVVTSGDPMGTAG 464
|
|
| pyruv_kin |
TIGR01064 |
pyruvate kinase; This enzyme is a homotetramer. Some forms are active only in the presence of ... |
5-471 |
0e+00 |
|
pyruvate kinase; This enzyme is a homotetramer. Some forms are active only in the presence of fructose-1,6-bisphosphate or similar phosphorylated sugars. [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 273424 [Multi-domain] Cd Length: 472 Bit Score: 622.38 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 5 RKTKIICTLGPAVDSEEMIRKLILAGMNAARFNFSHGTHESHLAQLTKLKRVRDELGIPVAAIMDTKGPEIRIKTFKDGR 84
Cdd:TIGR01064 1 RRTKIVCTIGPATNSPEMLKKLLDAGMNVARLNFSHGSHEEHGKRIENVREAAEKLGRPVAILLDTKGPEIRTGEIKGGE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 85 IELKKDDIFTLTTAD--CEGDATRVSVTYANLHNEVVPGNHILVDDGLIDLLVQEIKGQEIVCTVENGGPLSNNKSINIP 162
Cdd:TIGR01064 81 VKLKKGDKVIITTDDikGEGDEEKVYVDYKGLTKDVVEGDKILVDDGKISLVVVSVEGDKVICEVLNGGTLKSKKGVNLP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 163 DVHILLPSLTEKDKEDLKFAVENDFDFIAASFVRKASDVEDIRAWLNECGGEKIRIISKIENREGVDNLAEIIAASDGVM 242
Cdd:TIGR01064 161 GADVDLPALSEKDKKDLKFGVEQGVDMVAASFVRTAEDVLEVREVLGEKGAKDVKIIAKIENQEGVDNIDEIAEASDGIM 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 243 VARGDLGVEIPAQEVPILQKKMIKATTMAGKPVITATQMLDSMIRNPRPTRAEVSDVANAVFDGTSCVMLSGETASGKYP 322
Cdd:TIGR01064 241 VARGDLGVEIPAEEVPIAQKKMIRKCNRAGKPVITATQMLDSMIKNPRPTRAEVSDVANAVLDGTDAVMLSGETAKGKYP 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 323 IEAVEAMVSTVKAAESAINYWGRFREHSLqpgVSSINDAITHTCCMTAMD----LNATAILAPTESGYTAKVISRFRPAC 398
Cdd:TIGR01064 321 VEAVQMMAKIAKEAEKALAYLTNFNDRKN---SDPKPSTITEAIALSAVEaaekLDAKAIVVLTESGRTARLLSKYRPNA 397
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2538191712 399 PIVAVCQSEKVRRQLAISWGVHSYLTG-FVDSTDRLFSMSVEVARKEGAVKCGDTVVITAGVPIGKSGTTNLIK 471
Cdd:TIGR01064 398 PIIAVTPNERVARQLALYWGVFPFLVDeEPSDTDARVNKALELLKEKGIVKKGDLVVVIQGGPIGGEGGTNTIR 471
|
|
| Pyruvate_Kinase |
cd00288 |
Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of ... |
4-475 |
0e+00 |
|
Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low affinity T state. PK exists as several different isozymes, depending on organism and tissue type. In mammals, there are four PK isozymes: R, found in red blood cells, L, found in liver, M1, found in skeletal muscle, and M2, found in kidney, adipose tissue, and lung. PK forms a homotetramer, with each subunit containing three domains. The T state to R state transition of PK is more complex than in most allosteric enzymes, involving a concerted rotation of all 3 domains of each monomer in the homotetramer.
Pssm-ID: 238178 [Multi-domain] Cd Length: 480 Bit Score: 600.46 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 4 MRKTKIICTLGPAVDSEEMIRKLILAGMNAARFNFSHGTHESHLAQLTKLKRVRDELGIPVAAIMDTKGPEIRIKTFKDG 83
Cdd:cd00288 1 LRRTKIVCTIGPATDSVENLKKLIKAGMNVARMNFSHGSHEYHQSRIDNVREAAEKTGGPVAIALDTKGPEIRTGLFKGG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 84 R-IELKKDDIFTLTT--ADCEGDATRVSVTYANLHNEVVPGNHILVDDGLIDLLVQEIKG-QEIVCTVENGGPLSNNKSI 159
Cdd:cd00288 81 KdISLKAGDKFLVTTdpAAKKGTKEKIYVDYKNLTKDVSPGNTILVDDGLLSLKVLSKDDdKTLVCEVLNGGVLGSRKGV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 160 NIPDVHILLPSLTEKDKEDLKFAVENDFDFIAASFVRKASDVEDIRAWLNEcGGEKIRIISKIENREGVDNLAEIIAASD 239
Cdd:cd00288 161 NLPGTDVDLPALSEKDKADLRFGVEQGVDMIFASFVRKASDVLEIREVLGE-KGKDIKIIAKIENQEGVNNFDEILEASD 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 240 GVMVARGDLGVEIPAQEVPILQKKMIKATTMAGKPVITATQMLDSMIRNPRPTRAEVSDVANAVFDGTSCVMLSGETASG 319
Cdd:cd00288 240 GIMVARGDLGVEIPAEEVFLAQKMLIAKCNLAGKPVITATQMLESMIYNPRPTRAEVSDVANAVLDGTDCVMLSGETAKG 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 320 KYPIEAVEAMVSTVKAAESAINYWGRF-REHSLQPGVSSINDAITHTCCMTAMDLNATAILAPTESGYTAKVISRFRPAC 398
Cdd:cd00288 320 KYPVEAVKAMARICLEAEKALSHRVLFnEMRRLTPRPTSTTEAVAMSAVRAAFELGAKAIVVLTTSGRTARLVSKYRPNA 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 399 PIVAVCQSEKVRRQLAISWGVHSYLT-----GFVDSTDRLFSMSVEVARKEGAVKCGDTVVITAGVPIGkSGTTNLIKAQ 473
Cdd:cd00288 400 PIIAVTRNEQTARQLHLYRGVYPVLFeepkpGWQEDTDARLKAAVNVAKEKGLLKKGDLVVVVQGWPVG-SGSTNTMRIL 478
|
..
gi 2538191712 474 VV 475
Cdd:cd00288 479 TV 480
|
|
| PK |
pfam00224 |
Pyruvate kinase, barrel domain; This domain of the is actually a small beta-barrel domain ... |
4-346 |
1.32e-165 |
|
Pyruvate kinase, barrel domain; This domain of the is actually a small beta-barrel domain nested within a larger TIM barrel. The active site is found in a cleft between the two domains.
Pssm-ID: 395168 [Multi-domain] Cd Length: 348 Bit Score: 470.70 E-value: 1.32e-165
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 4 MRKTKIICTLGPAVDSEEMIRKLILAGMNAARFNFSHGTHESHLAQLTKLKRVRDELGIPVAAIMDTKGPEIRIKTFKDG 83
Cdd:pfam00224 1 LRRTKIVCTIGPASNSVENLEKLIEAGANVARMNFSHGSHEYHQSRIDNVREAEEKTGGTVAIALDTKGPEIRTGNTKDG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 84 R--IELKKDDIFTLTTAD---CEGDATRVSVTYANLHNEVVPGNHILVDDGLIDLLVQEIKGQE-IVCTVENGGPLSNNK 157
Cdd:pfam00224 81 KkdIELKAGDEMIVSTDAkykGACDDEMIYVDYKNIVKDVSVGGTILVDDGLLSLKVLSKDDDKtLVVEVLNGGVIGSRK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 158 SINIPDVHILLPSLTEKDKEDLKFAVENDFDFIAASFVRKASDVEDIRAWLNEcGGEKIRIISKIENREGVDNLAEIIAA 237
Cdd:pfam00224 161 GVNLPGTDVDLPALSEKDKADLRFGVKNGVDMIFASFVRKASDVLEIREVLGE-AGKNIQIIAKIENQEGVNNFDEILEA 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 238 SDGVMVARGDLGVEIPAQEVPILQKKMIKATTMAGKPVITATQMLDSMIRNPRPTRAEVSDVANAVFDGTSCVMLSGETA 317
Cdd:pfam00224 240 TDGIMVARGDLGIEIPAEEVFLAQKMLIAKCNLAGKPVITATQMLESMIYNPRPTRAEVSDVANAVLDGTDCVMLSGETA 319
|
330 340
....*....|....*....|....*....
gi 2538191712 318 SGKYPIEAVEAMVSTVKAAESAINYWGRF 346
Cdd:pfam00224 320 KGNYPVEAVRMMHEICLEAEKALPHRNLF 348
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PykF |
COG0469 |
Pyruvate kinase [Carbohydrate transport and metabolism]; Pyruvate kinase is part of the ... |
4-475 |
0e+00 |
|
Pyruvate kinase [Carbohydrate transport and metabolism]; Pyruvate kinase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 440237 [Multi-domain] Cd Length: 471 Bit Score: 775.75 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 4 MRKTKIICTLGPAVDSEEMIRKLILAGMNAARFNFSHGTHESHLAQLTKLKRVRDELGIPVAAIMDTKGPEIRIKTFKDG 83
Cdd:COG0469 2 MRRTKIVATLGPASDSPEVLRKLIEAGMDVARLNFSHGDHEEHRERIELIREAAKELGRPVAILLDLQGPKIRTGKFKEG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 84 RIELKKDDIFTLTTADCEGDATRVSVTYANLHNEVVPGNHILVDDGLIDLLVQEIKGQEIVCTVENGGPLSNNKSINIPD 163
Cdd:COG0469 82 PVELKKGDTFTLTTDDVEGDAERVSVTYPELPEDVKPGDRILLDDGKIELRVEEVEGDEVVCEVVNGGVLSSRKGVNLPG 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 164 VHILLPSLTEKDKEDLKFAVENDFDFIAASFVRKASDVEDIRAWLNECGGeKIRIISKIENREGVDNLAEIIAASDGVMV 243
Cdd:COG0469 162 VGLSLPALTEKDREDLKFALELGVDFIALSFVRSAEDVLEARELLEEAGG-RAPIIAKIEKPEAVENLDEIIEASDGIMV 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 244 ARGDLGVEIPAQEVPILQKKMIKATTMAGKPVITATQMLDSMIRNPRPTRAEVSDVANAVFDGTSCVMLSGETASGKYPI 323
Cdd:COG0469 241 ARGDLGVEIPLEEVPLIQKRIIRKARRAGKPVITATQMLESMIENPRPTRAEVSDVANAVLDGTDAVMLSGETAVGKYPV 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 324 EAVEAMVSTVKAAESAINYWGRFREHSLQPGvSSINDAITHTCCMTAMDLNATAILAPTESGYTAKVISRFRPACPIVAV 403
Cdd:COG0469 321 EAVETMARIAEEAEKSLDYRRILDRLRDEPE-RTITDAIARAAVELAEDLGAKAIVAFTESGSTARRISRYRPKVPILAL 399
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2538191712 404 CQSEKVRRQLAISWGVHSYLTGFVDSTDRLFSMSVEVARKEGAVKCGDTVVITAGVPIGKSGTTNLIKAQVV 475
Cdd:COG0469 400 TPNERTARRLALVWGVYPVLVDDVESTDEMIEEAVEALLEEGLVKPGDLVVITAGVPVGVPGTTNTLKVHRV 471
|
|
| PRK05826 |
PRK05826 |
pyruvate kinase; Provisional |
4-465 |
0e+00 |
|
pyruvate kinase; Provisional
Pssm-ID: 235619 [Multi-domain] Cd Length: 465 Bit Score: 657.61 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 4 MRKTKIICTLGPAVDSEEMIRKLILAGMNAARFNFSHGTHESHLAQLTKLKRVRDELGIPVAAIMDTKGPEIRIKTFKDG 83
Cdd:PRK05826 3 LRRTKIVATLGPASDSPENLEKLIEAGVNVVRLNFSHGSHEEHGKRAALVREIAAKLGRPVAILLDLKGPKIRVGKFKEG 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 84 RIELKKDDIFTLTTADC-EGDATRVSVTYANLHNEVVPGNHILVDDGLIDLLVQEIKGQEIVCTVENGGPLSNNKSINIP 162
Cdd:PRK05826 83 KITLKTGDKFTLDTDQKeEGDKERVGVDYKGLPKDVKPGDILLLDDGKLQLKVVEVDGDEVETEVKNGGPLSNNKGINIP 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 163 DVHILLPSLTEKDKEDLKFAVENDFDFIAASFVRKASDVEDIRAWLNECGGEKIRIISKIENREGVDNLAEIIAASDGVM 242
Cdd:PRK05826 163 GGGLSLPALTEKDKADIKFAAEQGVDYIAVSFVRSAEDVEEARRLLREAGCPHAKIIAKIERAEAVDNIDEIIEASDGIM 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 243 VARGDLGVEIPAQEVPILQKKMIKATTMAGKPVITATQMLDSMIRNPRPTRAEVSDVANAVFDGTSCVMLSGETASGKYP 322
Cdd:PRK05826 243 VARGDLGVEIPDEEVPGLQKKIIRKAREAGKPVITATQMLESMIENPRPTRAEVSDVANAVLDGTDAVMLSGETAAGKYP 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 323 IEAVEAMVSTVKAAESA--INYWGRFREHSLqpgvSSINDAITHTCCMTAMDLN-ATAILAPTESGYTAKVISRFRPACP 399
Cdd:PRK05826 323 VEAVEAMARICKGAEKEfsINLSKHRLDRQF----DRIDEAIAMSAMYAANHLKgVKAIVALTESGRTARLISRFRPGAP 398
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2538191712 400 IVAVCQSEKVRRQLAISWGVHSYLTGFVDSTDRLFSMSVEVARKEGAVKCGDTVVITAGVPIGKSG 465
Cdd:PRK05826 399 IFAVTRDEKTQRRLALYRGVYPVLFDSAADTDDAAEEALRLLLEKGLVESGDLVVVTSGDPMGTAG 464
|
|
| PRK06354 |
PRK06354 |
pyruvate kinase; Provisional |
4-475 |
0e+00 |
|
pyruvate kinase; Provisional
Pssm-ID: 235784 [Multi-domain] Cd Length: 590 Bit Score: 628.49 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 4 MRKTKIICTLGPAVDSEEMIRKLILAGMNAARFNFSHGTHESHLAQLTKLKRVRDELGIPVAAIMDTKGPEIRIKTFKDG 83
Cdd:PRK06354 7 MRRTKIVATIGPASESPEKLRQLIEAGATTARLNFSHGDHEEHGARIKNIREASKKLGKTVGILQDLQGPKIRLGRFEDG 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 84 RIELKKDDIFTLTTADCEGDATRVSVTYANLHNEVVPGNHILVDDGLIDLLVQEI--KGQEIVCTVENGGPLSNNKSINI 161
Cdd:PRK06354 87 PIELKTGDEFILTSREVLGTQEKFSVTYDGLADEVPVGSRILLDDGLIELEVEEVdkADGELHCKVLVGGVLSNKKGVNF 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 162 PDVHILLPSLTEKDKEDLKFAVENDFDFIAASFVRKASDVEDIRAWLNECGGEKIRIISKIENREGVDNLAEIIAASDGV 241
Cdd:PRK06354 167 PGVSLSLPAITEKDREDLIFGLEQGVDWIALSFVRNPSDVLEIRELIEEHNGKHIPIIAKIEKQEAIDNIDAILELCDGL 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 242 MVARGDLGVEIPAQEVPILQKKMIKATTMAGKPVITATQMLDSMIRNPRPTRAEVSDVANAVFDGTSCVMLSGETASGKY 321
Cdd:PRK06354 247 MVARGDLGVEIPAEEVPLLQKRLIKKANRLGKPVITATQMLDSMQRNPRPTRAEASDVANAILDGTDAVMLSNETAAGDY 326
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 322 PIEAVEAMVSTVKAAESAINYWGRFREHSLQpgVSSINDAITHTCCMTAMDLNATAILAPTESGYTAKVISRFRPACPIV 401
Cdd:PRK06354 327 PVEAVQTMATIAVRIEKDLPYRDILSKRPEF--TTTITNAISQAVSHIALQLDAAAIVTLTKSGATARNVSKYRPKTPIL 404
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2538191712 402 AVCQSEKVRRQLAISWGVHSYLTGFVDSTDRLFSMSVEVARKEGAVKCGDTVVITAGVPIGKSGTTNLIKAQVV 475
Cdd:PRK06354 405 AVTPNESVARRLQLVWGVTPLLVLDAPSTDETFDAAINVAQESGLLKQGDLVVITAGTLVGESGSTDLMKVHVV 478
|
|
| pyruv_kin |
TIGR01064 |
pyruvate kinase; This enzyme is a homotetramer. Some forms are active only in the presence of ... |
5-471 |
0e+00 |
|
pyruvate kinase; This enzyme is a homotetramer. Some forms are active only in the presence of fructose-1,6-bisphosphate or similar phosphorylated sugars. [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 273424 [Multi-domain] Cd Length: 472 Bit Score: 622.38 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 5 RKTKIICTLGPAVDSEEMIRKLILAGMNAARFNFSHGTHESHLAQLTKLKRVRDELGIPVAAIMDTKGPEIRIKTFKDGR 84
Cdd:TIGR01064 1 RRTKIVCTIGPATNSPEMLKKLLDAGMNVARLNFSHGSHEEHGKRIENVREAAEKLGRPVAILLDTKGPEIRTGEIKGGE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 85 IELKKDDIFTLTTAD--CEGDATRVSVTYANLHNEVVPGNHILVDDGLIDLLVQEIKGQEIVCTVENGGPLSNNKSINIP 162
Cdd:TIGR01064 81 VKLKKGDKVIITTDDikGEGDEEKVYVDYKGLTKDVVEGDKILVDDGKISLVVVSVEGDKVICEVLNGGTLKSKKGVNLP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 163 DVHILLPSLTEKDKEDLKFAVENDFDFIAASFVRKASDVEDIRAWLNECGGEKIRIISKIENREGVDNLAEIIAASDGVM 242
Cdd:TIGR01064 161 GADVDLPALSEKDKKDLKFGVEQGVDMVAASFVRTAEDVLEVREVLGEKGAKDVKIIAKIENQEGVDNIDEIAEASDGIM 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 243 VARGDLGVEIPAQEVPILQKKMIKATTMAGKPVITATQMLDSMIRNPRPTRAEVSDVANAVFDGTSCVMLSGETASGKYP 322
Cdd:TIGR01064 241 VARGDLGVEIPAEEVPIAQKKMIRKCNRAGKPVITATQMLDSMIKNPRPTRAEVSDVANAVLDGTDAVMLSGETAKGKYP 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 323 IEAVEAMVSTVKAAESAINYWGRFREHSLqpgVSSINDAITHTCCMTAMD----LNATAILAPTESGYTAKVISRFRPAC 398
Cdd:TIGR01064 321 VEAVQMMAKIAKEAEKALAYLTNFNDRKN---SDPKPSTITEAIALSAVEaaekLDAKAIVVLTESGRTARLLSKYRPNA 397
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2538191712 399 PIVAVCQSEKVRRQLAISWGVHSYLTG-FVDSTDRLFSMSVEVARKEGAVKCGDTVVITAGVPIGKSGTTNLIK 471
Cdd:TIGR01064 398 PIIAVTPNERVARQLALYWGVFPFLVDeEPSDTDARVNKALELLKEKGIVKKGDLVVVIQGGPIGGEGGTNTIR 471
|
|
| Pyruvate_Kinase |
cd00288 |
Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of ... |
4-475 |
0e+00 |
|
Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low affinity T state. PK exists as several different isozymes, depending on organism and tissue type. In mammals, there are four PK isozymes: R, found in red blood cells, L, found in liver, M1, found in skeletal muscle, and M2, found in kidney, adipose tissue, and lung. PK forms a homotetramer, with each subunit containing three domains. The T state to R state transition of PK is more complex than in most allosteric enzymes, involving a concerted rotation of all 3 domains of each monomer in the homotetramer.
Pssm-ID: 238178 [Multi-domain] Cd Length: 480 Bit Score: 600.46 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 4 MRKTKIICTLGPAVDSEEMIRKLILAGMNAARFNFSHGTHESHLAQLTKLKRVRDELGIPVAAIMDTKGPEIRIKTFKDG 83
Cdd:cd00288 1 LRRTKIVCTIGPATDSVENLKKLIKAGMNVARMNFSHGSHEYHQSRIDNVREAAEKTGGPVAIALDTKGPEIRTGLFKGG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 84 R-IELKKDDIFTLTT--ADCEGDATRVSVTYANLHNEVVPGNHILVDDGLIDLLVQEIKG-QEIVCTVENGGPLSNNKSI 159
Cdd:cd00288 81 KdISLKAGDKFLVTTdpAAKKGTKEKIYVDYKNLTKDVSPGNTILVDDGLLSLKVLSKDDdKTLVCEVLNGGVLGSRKGV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 160 NIPDVHILLPSLTEKDKEDLKFAVENDFDFIAASFVRKASDVEDIRAWLNEcGGEKIRIISKIENREGVDNLAEIIAASD 239
Cdd:cd00288 161 NLPGTDVDLPALSEKDKADLRFGVEQGVDMIFASFVRKASDVLEIREVLGE-KGKDIKIIAKIENQEGVNNFDEILEASD 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 240 GVMVARGDLGVEIPAQEVPILQKKMIKATTMAGKPVITATQMLDSMIRNPRPTRAEVSDVANAVFDGTSCVMLSGETASG 319
Cdd:cd00288 240 GIMVARGDLGVEIPAEEVFLAQKMLIAKCNLAGKPVITATQMLESMIYNPRPTRAEVSDVANAVLDGTDCVMLSGETAKG 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 320 KYPIEAVEAMVSTVKAAESAINYWGRF-REHSLQPGVSSINDAITHTCCMTAMDLNATAILAPTESGYTAKVISRFRPAC 398
Cdd:cd00288 320 KYPVEAVKAMARICLEAEKALSHRVLFnEMRRLTPRPTSTTEAVAMSAVRAAFELGAKAIVVLTTSGRTARLVSKYRPNA 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 399 PIVAVCQSEKVRRQLAISWGVHSYLT-----GFVDSTDRLFSMSVEVARKEGAVKCGDTVVITAGVPIGkSGTTNLIKAQ 473
Cdd:cd00288 400 PIIAVTRNEQTARQLHLYRGVYPVLFeepkpGWQEDTDARLKAAVNVAKEKGLLKKGDLVVVVQGWPVG-SGSTNTMRIL 478
|
..
gi 2538191712 474 VV 475
Cdd:cd00288 479 TV 480
|
|
| PRK06247 |
PRK06247 |
pyruvate kinase; Provisional |
1-470 |
0e+00 |
|
pyruvate kinase; Provisional
Pssm-ID: 180487 [Multi-domain] Cd Length: 476 Bit Score: 539.51 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 1 MSDMRKTKIICTLGPAVDSEEMIRKLILAGMNAARFNFSHGTHESHLAQLTKLKRVRDELGIPVAAIMDTKGPEIRIKTF 80
Cdd:PRK06247 1 MKRNRRVKILATLGPASSSEDMIRKLVEAGADVFRLNFSHGDHDDHRELYKRIREVEDETGRPIGILADLQGPKLRLGRF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 81 KDGRIELKKDDIFTLTTADCEGDATRVSVTYANLHNEVVPGNHILVDDGLIDLLVQEIKGQEIVCTVENGGPLSNNKSIN 160
Cdd:PRK06247 81 ADGKVQLANGQTFRLDVDDAPGDHDRVSLPHPEIAAALKPGDRLLVDDGKVRLVVEACDGDDVVCRVVEGGPVSDRKGVS 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 161 IPDVHILLPSLTEKDKEDLKFAVENDFDFIAASFVRKASDVEDIRAWLnecgGEKIRIISKIENREGVDNLAEIIAASDG 240
Cdd:PRK06247 161 LPGTVLSVSALTEKDRADLEFALELGVDWVALSFVQRPEDVEEVRKII----GGRVPVMAKIEKPQAIDRLEAIVEASDA 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 241 VMVARGDLGVEIPAQEVPILQKKMIKATTMAGKPVITATQMLDSMIRNPRPTRAEVSDVANAVFDGTSCVMLSGETASGK 320
Cdd:PRK06247 237 IMVARGDLGVEVPLEQVPLIQKRIIRAARRAGKPVVVATQMLESMIENPVPTRAEVSDVATAVLDGADAVMLSAETASGK 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 321 YPIEAVEAMVSTVKAAESAINYWGRFREHSLQPGvSSINDAITHTCCMTAMDLNATAILAPTESGYTAKVISRFRPACPI 400
Cdd:PRK06247 317 YPVEAVRTMARIIRQVERDPTYPPLIHAQRPQPE-ATKRDAISYAARDIAERLDLAALVAYTSSGDTALRAARERPPLPI 395
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 401 VAVCQSEKVRRQLAISWGVHSYLTGFVDSTDRLFSMSVEVARKEGAVKCGDTVVITAGVPIGKSGTTNLI 470
Cdd:PRK06247 396 LALTPNPETARRLALTWGVHCVVVDDARDTDDMVRRADRIALAEGFYKRGDRVVIVAGVPPGTPGSTNML 465
|
|
| PRK09206 |
PRK09206 |
pyruvate kinase PykF; |
4-475 |
0e+00 |
|
pyruvate kinase PykF;
Pssm-ID: 181699 [Multi-domain] Cd Length: 470 Bit Score: 534.25 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 4 MRKTKIICTLGPAVDSEEMIRKLILAGMNAARFNFSHGTHESHLAQLTKLKRVRDELGIPVAAIMDTKGPEIRIKTFKDG 83
Cdd:PRK09206 1 MKKTKIVCTIGPKTESEEMLTKLLDAGMNVMRLNFSHGDYAEHGQRIKNLRNVMSKTGKKAAILLDTKGPEIRTMKLEGG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 84 R-IELKKDDIFTLTT-ADCEGDATRVSVTYANLHNEVVPGNHILVDDGLIDLLVQEIKGQEIVCTVENGGPLSNNKSINI 161
Cdd:PRK09206 81 NdVSLKAGQTFTFTTdKSVVGNKERVAVTYEGFTADLSVGNTVLVDDGLIGMEVTAITGNEVICKVLNNGDLGENKGVNL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 162 PDVHILLPSLTEKDKEDLKFAVENDFDFIAASFVRKASDVEDIRAWLNECGGEKIRIISKIENREGVDNLAEIIAASDGV 241
Cdd:PRK09206 161 PGVSIALPALAEKDKQDLIFGCEQGVDFVAASFIRKRSDVLEIREHLKAHGGENIQIISKIENQEGLNNFDEILEASDGI 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 242 MVARGDLGVEIPAQEVPILQKKMIKATTMAGKPVITATQMLDSMIRNPRPTRAEVSDVANAVFDGTSCVMLSGETASGKY 321
Cdd:PRK09206 241 MVARGDLGVEIPVEEVIFAQKMMIEKCNRARKVVITATQMLDSMIKNPRPTRAEAGDVANAILDGTDAVMLSGESAKGKY 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 322 PIEAVEAMVSTVKAAESAINywGRFrEHSLQPGVSSINDAITHTCCMTAMDLNATAILAPTESGYTAKVISRFRPACPIV 401
Cdd:PRK09206 321 PLEAVSIMATICERTDRVMN--SRL-ESNNDNRKLRITEAVCRGAVETAEKLDAPLIVVATQGGKSARSVRKYFPDATIL 397
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2538191712 402 AVCQSEKVRRQLAISWGVHSYLTGFVDSTDRLFSMSVEVARKEGAVKCGDTVVITAGVpIGKSGTTNLIKAQVV 475
Cdd:PRK09206 398 ALTTNEKTARQLVLSKGVVPQLVKEIASTDDFYRLGKELALQSGLAQKGDVVVMVSGA-LVPSGTTNTASVHVL 470
|
|
| PK |
pfam00224 |
Pyruvate kinase, barrel domain; This domain of the is actually a small beta-barrel domain ... |
4-346 |
1.32e-165 |
|
Pyruvate kinase, barrel domain; This domain of the is actually a small beta-barrel domain nested within a larger TIM barrel. The active site is found in a cleft between the two domains.
Pssm-ID: 395168 [Multi-domain] Cd Length: 348 Bit Score: 470.70 E-value: 1.32e-165
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 4 MRKTKIICTLGPAVDSEEMIRKLILAGMNAARFNFSHGTHESHLAQLTKLKRVRDELGIPVAAIMDTKGPEIRIKTFKDG 83
Cdd:pfam00224 1 LRRTKIVCTIGPASNSVENLEKLIEAGANVARMNFSHGSHEYHQSRIDNVREAEEKTGGTVAIALDTKGPEIRTGNTKDG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 84 R--IELKKDDIFTLTTAD---CEGDATRVSVTYANLHNEVVPGNHILVDDGLIDLLVQEIKGQE-IVCTVENGGPLSNNK 157
Cdd:pfam00224 81 KkdIELKAGDEMIVSTDAkykGACDDEMIYVDYKNIVKDVSVGGTILVDDGLLSLKVLSKDDDKtLVVEVLNGGVIGSRK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 158 SINIPDVHILLPSLTEKDKEDLKFAVENDFDFIAASFVRKASDVEDIRAWLNEcGGEKIRIISKIENREGVDNLAEIIAA 237
Cdd:pfam00224 161 GVNLPGTDVDLPALSEKDKADLRFGVKNGVDMIFASFVRKASDVLEIREVLGE-AGKNIQIIAKIENQEGVNNFDEILEA 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 238 SDGVMVARGDLGVEIPAQEVPILQKKMIKATTMAGKPVITATQMLDSMIRNPRPTRAEVSDVANAVFDGTSCVMLSGETA 317
Cdd:pfam00224 240 TDGIMVARGDLGIEIPAEEVFLAQKMLIAKCNLAGKPVITATQMLESMIYNPRPTRAEVSDVANAVLDGTDCVMLSGETA 319
|
330 340
....*....|....*....|....*....
gi 2538191712 318 SGKYPIEAVEAMVSTVKAAESAINYWGRF 346
Cdd:pfam00224 320 KGNYPVEAVRMMHEICLEAEKALPHRNLF 348
|
|
| PLN02461 |
PLN02461 |
Probable pyruvate kinase |
6-454 |
3.14e-160 |
|
Probable pyruvate kinase
Pssm-ID: 215255 [Multi-domain] Cd Length: 511 Bit Score: 463.30 E-value: 3.14e-160
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 6 KTKIICTLGPAVDSEEMIRKLILAGMNAARFNFSHGTHESHLAQLTKLKRVRDELGIPVAAIMDTKGPEIRIKTFKDGR- 84
Cdd:PLN02461 22 KTKIVCTLGPASRSVPMLEKLLRAGMNVARFNFSHGSHEYHQETLDNLRQAMANTGILCAVMLDTKGPEIRTGFLKDGKp 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 85 IELKKDDIFTLTTA-DCEGDATRVSVTYANLHNEVVPGNHILVDDGLIDLLVQE--IKGQEIVCTVENGGPLSNNKSINI 161
Cdd:PLN02461 102 VQLKQGQEITITTDySIKGDENMIAMSYKKLAVDVKPGSVILCADGTITLTVLScdVEAGTVRCRCENSAMLGERKNVNL 181
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 162 PDVHILLPSLTEKDKED-LKFAVENDFDFIAASFVRKASDVEDIRAWLNEcGGEKIRIISKIENREGVDNLAEIIAASDG 240
Cdd:PLN02461 182 PGVVVDLPTLTEKDKEDiLQWGVPNKIDFIALSFVRKGSDLVEVRKVLGE-HAKSILLISKVENQEGLDNFDDILAESDA 260
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 241 VMVARGDLGVEIPAQEVPILQKKMIKATTMAGKPVITATQMLDSMIRNPRPTRAEVSDVANAVFDGTSCVMLSGETASGK 320
Cdd:PLN02461 261 FMVARGDLGMEIPIEKIFLAQKMMIYKCNLAGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGA 340
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 321 YPIEAVEAMVSTVKAAESAINYWGRFRE-HSLQPGVSSINDAITHTCCMTAMDLNATAILAPTESGYTAKVISRFRPACP 399
Cdd:PLN02461 341 YPELAVKTMARICREAEASLDYGALFKEiMRSAPLPMSPLESLASSAVRTANKVKASLIVVLTRGGTTARLVAKYRPAVP 420
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2538191712 400 IVAV-------------CQSEKVRRQLAISWGVHSYLT------GFVDSTDRLFSMSVEVARKEGAVKCGDTVV 454
Cdd:PLN02461 421 ILSVvvpeittdsfdwsCSDEAPARHSLIYRGLIPVLAegsakaTDSESTEEILEAAIEHAKKKGLCKPGDSVV 494
|
|
| PTZ00066 |
PTZ00066 |
pyruvate kinase; Provisional |
5-471 |
3.23e-148 |
|
pyruvate kinase; Provisional
Pssm-ID: 173361 [Multi-domain] Cd Length: 513 Bit Score: 433.03 E-value: 3.23e-148
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 5 RKTKIICTLGPAVDSEEMIRKLILAGMNAARFNFSHGTHESHLAQLTKLK-----RVRDELGIpvaaIMDTKGPEIRIKT 79
Cdd:PTZ00066 38 KKTHIVCTMGPACKNVETLVKLIDAGMNICRFNFSHGDHESHKKTLNNVReaakaRPNANLGI----LLDTKGPEIRTGF 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 80 FKDGR-IELKKDDIFTLTTA-DCEGDATRVSVTYANLHNEVVPGNHILVDDGLIDLLVQEIKGQEIVCTVENGGPLSNNK 157
Cdd:PTZ00066 114 LKNHKpITLKEGQTLKITTDyTFLGDETCISCSYKKLPQSVKVGNIILIADGSLSCKVLEVHDDYIITKVLNNATIGERK 193
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 158 SINIPDVHILLPSLTEKDKED-LKFAVENDFDFIAASFVRKASDVEDIRAWLNEcGGEKIRIISKIENREGVDNLAEIIA 236
Cdd:PTZ00066 194 NMNLPGVKVELPVIGEKDKNDiLNFAIPMGCDFIALSFVQSADDVRLCRQLLGE-RGRHIKIIPKIENIEGLINFDEILA 272
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 237 ASDGVMVARGDLGVEIPAQEVPILQKKMIKATTMAGKPVITATQMLDSMIRNPRPTRAEVSDVANAVFDGTSCVMLSGET 316
Cdd:PTZ00066 273 ESDGIMVARGDLGMEIPPEKVFLAQKMMISKCNVAGKPVITATQMLESMIKNPRPTRAESTDVANAVLDGTDCVMLSGET 352
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 317 ASGKYPIEAVEAMVSTVKAAESAINYWGRFRE-HSLQPGVSSINDAITHTCCMTAMDLNATAILAPTESGYTAKVISRFR 395
Cdd:PTZ00066 353 ANGKFPVEAVNIMAKICFEAETCIDYRVLYHAiHLAVPTPVSVQEAVARSAVETAEDINAKLIIALTETGNTARLISKYR 432
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2538191712 396 PACPIVAVCQSEKVRRQLAISWGVHSYLTGFVDSTDRLFSMSVEVARKEGAVKCGDTVVITAGVPIGKSGTTNLIK 471
Cdd:PTZ00066 433 PSCTILALSASPSVVKSLSVARGVTTYVVNSFQGTDVVIRNAIALAKERGLVESGDSAIAVHGVKEEVAGSSNLMK 508
|
|
| PTZ00300 |
PTZ00300 |
pyruvate kinase; Provisional |
31-455 |
4.44e-129 |
|
pyruvate kinase; Provisional
Pssm-ID: 140321 [Multi-domain] Cd Length: 454 Bit Score: 382.09 E-value: 4.44e-129
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 31 MNAARFNFSHGTHESHLAQLTKLKRVRDELGIPVAAIMDTKGPEIRIKTFKDGRIELKKDDIFTLTT----ADcEGDATR 106
Cdd:PTZ00300 1 MSVARMNFSHGSHEYHQTTINNVRQAAAELGVNIAIALDTKGPEIRTGLFVGGEAVMERGATCYVTTdpafAD-KGTKDK 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 107 VSVTYANLHNEVVPGNHILVDDGLIDLLVQEIKG-QEIVCTVENGGPLSNNKSINIPDVHILLPSLTEKDKEDLKFAVEN 185
Cdd:PTZ00300 80 FYIDYQNLSKVVRPGGYIYIDDGILILHVQSHEDeQTLKCTVTNAHTISDRRGVNLPGCDVDLPAVSAKDCADLQFGVEQ 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 186 DFDFIAASFVRKASDVEDIRAWLNECGGEkIRIISKIENREGVDNLAEIIAASDGVMVARGDLGVEIPAQEVPILQKKMI 265
Cdd:PTZ00300 160 GVDMIFASFIRSAEQVGEVRKALGAKGGD-IMIICKIENHQGVQNIDSIIEESDGIMVARGDLGVEIPAEKVVVAQKILI 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 266 KATTMAGKPVITATQMLDSMIRNPRPTRAEVSDVANAVFDGTSCVMLSGETASGKYPIEAVEAMVSTVKAAESAINYWGR 345
Cdd:PTZ00300 239 SKCNVAGKPVICATQMLESMTYNPRPTRAEVSDVANAVFNGADCVMLSGETAKGKYPNEVVQYMARICLEAQSAVNEYVF 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 346 FRE-HSLQPGVSSINDAITHTCCMTAMDLNATAILAPTESGYTAKVISRFRPACPIVAVCQSEKVRRQLAISWGVHSYL- 423
Cdd:PTZ00300 319 FNSiKKLQPIPMSAEEAVCSSAVNSVYETKAKALVVLSNTGRSARLVAKYRPNCPIVCVTTRLQTCRQLNITQGVESVFf 398
|
410 420 430
....*....|....*....|....*....|....*.
gi 2538191712 424 ----TGFVDSTDRLFSMSVEVARKEGAVKCGDTVVI 455
Cdd:PTZ00300 399 daerLGHDEGKEQRVAMGVGFAKSKGYVQSGDLMVV 434
|
|
| PLN02623 |
PLN02623 |
pyruvate kinase |
5-475 |
1.26e-118 |
|
pyruvate kinase
Pssm-ID: 215334 [Multi-domain] Cd Length: 581 Bit Score: 359.63 E-value: 1.26e-118
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 5 RKTKIICTLGPAVDSEEMIRKLILAGMNAARFNFSHGTHESHLAQLTKLKRVRDELGIPVAAIM-DTKGPEIRIKTFKDg 83
Cdd:PLN02623 110 RKTKIVCTIGPSTNTREMIWKLAEAGMNVARLNMSHGDHASHQKVIDLVKEYNAQSKDNVIAIMlDTKGPEVRSGDLPQ- 188
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 84 RIELKKDDIFTLTTADCEGDATRVSVTYANLHNEVVPGNHILVDDGLIDLLVQEIKGQEIVCTVENGGPLSNNKSINIPD 163
Cdd:PLN02623 189 PIMLEEGQEFTFTIKRGVSTEDCVSVNYDDFVNDVEVGDMLLVDGGMMSLAVKSKTSDSVKCEVVDGGELKSRRHLNVRG 268
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 164 VHILLPSLTEKDKEDLKFAVENDFDFIAASFVRKASDVEDIRAWLNECGGEkIRIISKIENREGVDNLAEIIAASDGVMV 243
Cdd:PLN02623 269 KSATLPSITEKDWEDIKFGVENKVDFYAVSFVKDAQVVHELKDYLKSCNAD-IHVIVKIESADSIPNLHSIITASDGAMV 347
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 244 ARGDLGVEIPAQEVPILQKKMIKATTMAGKPVITATQMLDSMIRNPRPTRAEVSDVANAVFDGTSCVMLSGETASGKYPI 323
Cdd:PLN02623 348 ARGDLGAELPIEEVPLLQEEIIRRCRSMGKPVIVATNMLESMIVHPTPTRAEVSDIAIAVREGADAVMLSGETAHGKFPL 427
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 324 EAVEAMV-------STVKAAESAINYWGRFREHslqpgvssINDAITHTCCMTAMDLNaTAILAPTESGYTAKVISRFRP 396
Cdd:PLN02623 428 KAVKVMHtvalrteATLPEGTTPPNLGQAFKNH--------MSEMFAFHATMMANTLG-TSIIVFTRTGFMAILLSHYRP 498
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 397 ACPIVAVCQSEKVRRQLAISWGVHSYLTGFVDSTDRLFSMSVEVARKEGAVKCGD--TVVITAGVPIGKSGTTNLIKAQV 474
Cdd:PLN02623 499 SGTIFAFTNEKRIQQRLALYQGVCPIYMQFSDDAEETFARALSLLLNKGMVKEGEevALVQSGRQPIWRSESTHHIQVRK 578
|
.
gi 2538191712 475 V 475
Cdd:PLN02623 579 V 579
|
|
| PLN02765 |
PLN02765 |
pyruvate kinase |
7-471 |
1.56e-103 |
|
pyruvate kinase
Pssm-ID: 215409 [Multi-domain] Cd Length: 526 Bit Score: 318.92 E-value: 1.56e-103
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 7 TKIICTLGPAVDSEEMIRKLILAGMNAARFNFSHGTHESHLAQLTKLKRVRDELGIPVAAIMDTKGPEIRIKTFKDGRIE 86
Cdd:PLN02765 30 TKIVGTLGPKSRSVEVIEACLKAGMSVARFDFSWGDAEYHQETLENLKIAVKNTKKLCAVMLDTVGPELQVINKTEKPIS 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 87 LKKDDIFTLTT-ADCEGDATRVSVTYANLHNEVVPGNHILVDDGL--------IDLLVQEIKGQEIVCTVENGGPLSNNK 157
Cdd:PLN02765 110 LKAGNTVTLTPdQSKEASSEVLPINFPGLAKAVKPGDTIFVGQYLftgsettsVWLEVDEVKGDDVVCTVKNSATLAGSL 189
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 158 -SINIPDVHILLPSLTEKDKEDLK-FAVENDFDFIAASFVRKASDVEDIRAWLNECGGEKIRIISKIENREGVDNLAEII 235
Cdd:PLN02765 190 fTLHVSQVRIDLPTLSEKDKEVIStWGVPNKIDFLSLSYTRHAEDVREAREFLSSLGLSQTQIFAKIENVEGLTHFDEIL 269
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 236 AASDGVMVARGDLGVEIPAQEVPILQKKMIKATTMAGKPVITaTQMLDSMIRNPRPTRAEVSDVANAVFDGTSCVMLSGE 315
Cdd:PLN02765 270 QEADGIILSRGNLGIDLPPEKVFLFQKAALYKCNMAGKPAVV-TRVVDSMTDNLRPTRAEATDVANAVLDGADAILLGAE 348
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 316 TASGKYPIEAVEAMVSTVKAAESAIN---YWGRFREHSLQPgvSSINDAITHTCCMTAMDLNATAILAPTESGYTAKVIS 392
Cdd:PLN02765 349 TLRGLYPVETISTVGRICAEAEKVFNqdlYFKKTVKYVGEP--MSHLESIASSAVRAAIKVKASVIIVFTSSGRAARLIA 426
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 393 RFRPACPIVAVC----QSEKVR---------RQLAISWGVHSYL-------TGFVDSTDRLFSMSVEVARKEGAVKCGDT 452
Cdd:PLN02765 427 KYRPTMPVLSVViprlKTNQLKwsftgafqaRQCLIVRGLFPMLadprhsaESTSATNESVLKVALDHGKAAGVIKSHDR 506
|
490
....*....|....*....
gi 2538191712 453 VVItagvpIGKSGTTNLIK 471
Cdd:PLN02765 507 VVV-----CQKVGDSSVVK 520
|
|
| PRK06739 |
PRK06739 |
pyruvate kinase; Validated |
10-337 |
5.16e-103 |
|
pyruvate kinase; Validated
Pssm-ID: 180676 [Multi-domain] Cd Length: 352 Bit Score: 311.49 E-value: 5.16e-103
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 10 ICTLGPAVDSEEMIRKLILAGMNAARFNFSHGTHESHLAQLTKLKRVRDELGIpvaaIMDTKGPEIRIKTFKDGRIELKK 89
Cdd:PRK06739 6 ICTIGPASNNKETLAQLINNGMKIVRLNLSHGTHESHKDIIRLVKSLDDSIKI----LGDVQGPKIRLGEIKGEQITLQA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 90 DDIFTLTTADCEGDATRVSVTYANLHNEVVPGNHILVDDGLIDLLVQEIKGQEIVCTVENGGPLSNNKSINIPDVHILLP 169
Cdd:PRK06739 82 GDSFILHTQPVTGSSTEASVDYEGIANDVKVGSRILMNDGEVELIVEKVSTDKIETKVKTGGNISSHKGVNLPGAIVRLP 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 170 SLTEKDKEDLKFAVENDFDFIAASFVRKASDVEDIRAWLNECGGEKIRIISKIENREGVDNLAEIIAASDGVMVARGDLG 249
Cdd:PRK06739 162 AITEKDKKDIQFLLEEDVDFIACSFVRKPSHIKEIRDFIQQYKETSPNLIAKIETMEAIENFQDICKEADGIMIARGDLG 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 250 VEIPAQEVPILQKKMIKATTMAGKPVITATQMLDSMIRNPRPTRAEVSDVANAVFDGTSCVMLSGETASGKYPIEAVEAM 329
Cdd:PRK06739 242 VELPYQFIPLLQKMMIQECNRTNTYVITATQMLQSMVDHSIPTRAEVTDVFQAVLDGTNAVMLSAESASGEHPIESVSTL 321
|
....*...
gi 2538191712 330 VSTVKAAE 337
Cdd:PRK06739 322 RLVSEFAE 329
|
|
| PLN02762 |
PLN02762 |
pyruvate kinase complex alpha subunit |
4-455 |
4.17e-101 |
|
pyruvate kinase complex alpha subunit
Pssm-ID: 215407 [Multi-domain] Cd Length: 509 Bit Score: 312.06 E-value: 4.17e-101
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 4 MRKTKIICTLGPAVDSEEMIRKLILAGMNAARFNFSHGTHESHLAQLTKLKRVRDELGIPVAAIMDTKGPEIRIKTFkDG 83
Cdd:PLN02762 24 TRRTKLVCTIGPACCGFEQLEALAMGGMNVARLNMCHGTREWHRDVIRRVRRLNEEKGFAVAVMMDTEGSEIHMGDL-GG 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 84 RIELKKDD----IFTLTTADCEGDATRVSVTYANLHNEVVPGNHILVDDGLIDLLVQEIKGQEIVCTVENGGPLSNNKSI 159
Cdd:PLN02762 103 ASSAKAEDgeewTFTVRKFDGSRPEFTIQVNYDGFAEDVKVGDELVVDGGMVRFEVIEKIGPDVKCKCTDPGLLLPRANL 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 160 N-------IPDVHILLPSLTEKDKEDLKFAVENDFDFIAASFVRKASDVEDIRAWLNECG-GEKIRIISKIENREGVDNL 231
Cdd:PLN02762 183 TfwrdgslVRERNAMLPTISSKDWLDIDFGISEGVDFIAVSFVKSAEVIKHLKSYIAARSrDSDIGVIAKIESLDSLKNL 262
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 232 AEIIAASDGVMVARGDLGVEIPAQEVPILQKKMIKATTMAGKPVITATQMLDSMIRNPRPTRAEVSDVANAVFDGTSCVM 311
Cdd:PLN02762 263 EEIIRASDGAMVARGDLGAQIPLEQVPSVQEKIVRLCRQLNKPVIVASQLLESMIEYPTPTRAEVADVSEAVRQRADALM 342
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 312 LSGETASGKYPIEAveamVSTVKAAESAINYWGRFREH----SLQPGVSSINDAITHTCCMTAM----DLNATAILAPTE 383
Cdd:PLN02762 343 LSGESAMGLYPEKA----LSVLRSVSLRMELWSREEKRhealELPQLSSSLSDRISEEICNSAAkmanNLGVDAIFVYTK 418
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2538191712 384 SGYTAKVISRFRPACPIVAVCQSEKVRRQLAISWGVHSYLTGFVDSTDRLFSMSVEVARKEGAVKCGDTVVI 455
Cdd:PLN02762 419 HGHMASLLSRNRPDCPIFAFTDTTSVRRRLNLQWGLIPFRLDFSDDMESNLNKTFSLLKARGMIKSGDLVIA 490
|
|
| PykA2 |
COG3848 |
Phosphohistidine swiveling domain of PEP-utilizing enzymes [Signal transduction mechanisms]; |
271-475 |
7.49e-77 |
|
Phosphohistidine swiveling domain of PEP-utilizing enzymes [Signal transduction mechanisms];
Pssm-ID: 443058 Cd Length: 321 Bit Score: 243.27 E-value: 7.49e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 271 AGKPVITATQMLDSMIRNPRPTRAEVSDVANAVFDGTSCVMLSGETASGKYPIEAVEAMVSTVKAAESAINYWGRFREHS 350
Cdd:COG3848 5 AGKPVITATQMLDSMMRNPRPTRAEAADVANAIFDGTDAIMLSGETAAGKYPVEAVVTMVRIAERAEEDLEYREQRVPRA 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 351 LQPGVSsINDAITHTCCMTAMDLNATAILAPTESGYTAKVISRFRPACPIVAVCQSEKVRRQLAISWGVHSYLTGFVDST 430
Cdd:COG3848 85 KESSTT-ITDAISHAVATTAADLGAAAIITATESGATARMVSKYRPKAPIIAVTPSERVARQLSLVWGVYPLLVEESAST 163
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 2538191712 431 DRLFSMSVEVARKEGAVKCGDTVVITAGVPIGKSGTTNLIKAQVV 475
Cdd:COG3848 164 DEMFAVAVALALEAGLVKDGDLVVITAGVPVGVSGTTNLLKVHVV 208
|
|
| PRK08187 |
PRK08187 |
pyruvate kinase; Validated |
2-327 |
4.27e-54 |
|
pyruvate kinase; Validated
Pssm-ID: 236178 Cd Length: 493 Bit Score: 188.69 E-value: 4.27e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 2 SDMRKTKIICTL-GPAVDSEEMIRKLILAGMNAARFNFSHGTHESHLAQLTKLKRVRDELGIPVAAIMDTKGPEIRIKTF 80
Cdd:PRK08187 130 PAARRTRIMVTLpSEAADDPDFVLRLAERGMDCARINCAHDDPAAWQAMIGHLRQAERATGRRCKILMDLAGPKIRTGAV 209
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 81 --KDGRIELKKDDIFTLTTADC----EGDATRVSVTYANLHNEVVPGNHILVDDGLIDLLVQEIKGQEIVCTV----ENG 150
Cdd:PRK08187 210 agPLGKTRLYTGDRLALVAQGPprriDEEHFQVTCTLPEILARLAVGARVWIDDGKLGARVERVGPGGALLEVtharPKG 289
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 151 GPLSNNKSINIPDVHILLPSLTEKDKEDLKFAVENDfDFIAASFVRKASDVEDIRAWLNECGGEKIR---IISKIENREG 227
Cdd:PRK08187 290 LKLKPEKGLNFPDTALDLPALTEKDRADLDFVARHA-DLVGYSFVQSPGDVEALQAALAARRPDDWRklgLVLKIETPRA 368
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 228 VDNLAEIIAASDG-----VMVARGDLGVEIPAQEVPILQKKMIKATTMAGKPVITATQMLDSMIRNPRPTRAEVSDVANA 302
Cdd:PRK08187 369 VANLPELIVQAAGrqpfgVMIARGDLAVEIGFERLAEMQEEILWLCEAAHVPVIWATQVLEGLVKKGLPSRAEMTDAAMA 448
|
330 340
....*....|....*....|....*
gi 2538191712 303 vfDGTSCVMLSgetaSGKYPIEAVE 327
Cdd:PRK08187 449 --ARAECVMLN----KGPYLVEAVT 467
|
|
| PK_C |
pfam02887 |
Pyruvate kinase, alpha/beta domain; As well as being found in pyruvate kinase this family is ... |
360-471 |
3.13e-45 |
|
Pyruvate kinase, alpha/beta domain; As well as being found in pyruvate kinase this family is found as an isolated domain in some bacterial proteins.
Pssm-ID: 460738 [Multi-domain] Cd Length: 114 Bit Score: 153.40 E-value: 3.13e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 360 DAITHTCCMTAMDLNATAILAPTESGYTAKVISRFRPACPIVAVCQSEKVRRQLAISWGVHSYLTGFVDSTDRLFSMSVE 439
Cdd:pfam02887 1 EAIAHAAVEAAEELGAKAIVVLTESGYTARLISRYRPGVPIIAVTPNELTARQLALYWGVYPVLFDEAETTDEMLRRAVK 80
|
90 100 110
....*....|....*....|....*....|..
gi 2538191712 440 VARKEGAVKCGDTVVITAGVPIGKSGTTNLIK 471
Cdd:pfam02887 81 VAKEAGLVKKGDLVVITAGVPFGVSGTTNTLK 112
|
|
| PRK14725 |
PRK14725 |
pyruvate kinase; Provisional |
80-327 |
3.20e-43 |
|
pyruvate kinase; Provisional
Pssm-ID: 237804 Cd Length: 608 Bit Score: 161.27 E-value: 3.20e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 80 FKDGRIELKKDDIFTLTTADCEGDAT-------RVSVTYANLHNEVVPGNHILVDDGLIDLLVQEIKGQEIVCTVENGGP 152
Cdd:PRK14725 328 PVEQKLRLKVGDRLVLTRDDAPGDPAqgdappaRISCTLPEAFRAARVGERVWFDDGKIGAVVVKVEADEVELRITHARP 407
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 153 ----LSNNKSINIPDVHILLPSLTEKDKEDLKFAVENDfDFIAASFVRKASDVEDIRAWLNECGGEKIRIISKIENREGV 228
Cdd:PRK14725 408 ggskLKAGKGINLPDSHLPLPALTDKDLEDLAFVAKHA-DIVALSFVRSPEDVRLLLDALEKLGADDLGVVLKIETRRAF 486
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 229 DNLAEII-----AASDGVMVARGDLGVEIPAQEVPILQKKMIKATTMAGKPVITATQMLDSMIRNPRPTRAEVSDVANAV 303
Cdd:PRK14725 487 ENLPRILleamrHPRFGVMIARGDLAVEVGFERLAEVQEEILWLCEAAHVPVIWATQVLESLAKKGLPSRAEITDAAMAL 566
|
250 260
....*....|....*....|....
gi 2538191712 304 fdGTSCVMLSgetaSGKYPIEAVE 327
Cdd:PRK14725 567 --RAECVMLN----KGPHIVEAVR 584
|
|
| CitE |
COG2301 |
Citrate lyase beta subunit [Carbohydrate transport and metabolism]; |
172-310 |
9.98e-04 |
|
Citrate lyase beta subunit [Carbohydrate transport and metabolism];
Pssm-ID: 441876 Cd Length: 288 Bit Score: 40.91 E-value: 9.98e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2538191712 172 TEKDKEDLKFAVENDFDFIAASFVRKASDVEDIRAWLNECG--GEKIRIISKIENREGVDNLAEIIAASDGVMVAR---- 245
Cdd:COG2301 74 TPWGLDDLAALVGAGLDGIVLPKVESAEDVRALAALLTELEaeGGSIPLMALIETARGLLNAAEIAAASPRVEALVfgae 153
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2538191712 246 ---GDLGVEIPAQEVPILQ--KKMIKATTMAGKPVItatqmlDSM---IRNPRPTRAEVSDVANAVFDGTSCV 310
Cdd:COG2301 154 dlaADLGARRTRDGDELLYarSRIVLAARAAGLAAI------DGVytdFRDLEGLRAEARRARALGFDGKTAI 220
|
|
| |
