|
Name |
Accession |
Description |
Interval |
E-value |
| MrcA |
COG5009 |
Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis]; |
1-789 |
0e+00 |
|
Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 444033 [Multi-domain] Cd Length: 785 Bit Score: 666.09 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 1 MKIKKstYVFVCGLFFCAIFFGAGLGLALSNTKFIKDNEQFTEFSTSLPTKLLDINGELITELAsEEKREIISIRDLPQC 80
Cdd:COG5009 1 MRLLK--ILLILLLLLLLLGALAVAGLYLYLSPDLPDVETLKDYQPPTPSRVYSADGKLIAEFG-EERRIPVPIEEIPPL 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 81 MLDALITREDRLFYSHHGYSVKALFRAVFGKL-TGMSLGGGSTLTQQIAGTLFCDRtDMSIRRKLKELWWAIQMERRYTK 159
Cdd:COG5009 78 LINAFLAAEDKRFYEHPGVDPIGIARAAVVNLrTGRRVQGGSTITQQVAKNFLLSP-ERTLTRKIKEAILALRIEQELSK 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 160 DEILELYLNKIYFGGGTYGVSAASKYYFGHDATEITPAEAAILVIQLSNPAFYNPFEYPNRAMDRQKDVLSTMVSAGYIS 239
Cdd:COG5009 157 DEILELYLNKIYLGHRAYGVAAAAQTYFGKSLDELTLAEAAMLAGLPKAPSRYNPIRNPERALERRNYVLGRMLELGYIT 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 240 KEQADESFDdywANFDYTRTATAAvfnhDDNAPWFSEYVRRELGNLiYGTEDIYSSGFTVNTTLNLKNQAVAQDVMDRY- 318
Cdd:COG5009 237 QAEYEAAKA---EPLTARYHGASA----EVDAPYFAEMVRRELVER-YGEDALYTGGLKVYTTLDPRLQEAAEKALRDGl 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 319 IRYANRTYQRSTGERTNQAFSvytPMTELLALTFNLNS------LKVSEQRNEAISKATYTSQINpvMDVMSLM--FGVD 390
Cdd:COG5009 309 LAYDRRHGYRGPEAHLDLAEE---DWDEALAEVPDVGDlrpavvLEVDDKSARVGLRDGETGTLP--LEGLKWArpYIND 383
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 391 SLKLGIVNKANQQAK----VKVSKTT-----------IEGTMIALENDTGYITSLVGGSKFDsENQFIRAVQAKLQPGSA 455
Cdd:COG5009 384 NRRGPAPKSASDVLKpgdvIRVRPVAdggwrlrqipeVQGALVALDPHTGAVLALVGGFDFE-QSKFNRATQAKRQPGSS 462
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 456 FKPLYYSAAIDsRKFTPTSIISDTPVVFHT-ADGKPYIPQNFRGEWKGDVELWYALAHSMNVPSLKVLDGIGFEAGINRs 534
Cdd:COG5009 463 FKPFVYAAALD-NGYTPATIINDAPIVFDDgGGGGVWRPKNYSGKFYGPTTLREALEKSRNLVTVRLLQDVGIDYVIDY- 540
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 535 IALLGIPKEevpyrgFVPGYPIGLGVCSVRPVELARAYSVFASGGKEVTPIAIRSVEDKNGNVIL--NPEKELRTALQAK 612
Cdd:COG5009 541 AERFGIYSK------LPPNLSLALGSGEVTPLEMARAYAVFANGGYRVEPYLIDRIEDRNGKVIYraDPARACEDCDAAE 614
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 613 GAAA---------QVISPQTAFVMTELLQNTVRSGTLAGPSSNGdklrykdsnghlykIPAAGKTGTTQNWADAWAVGFT 683
Cdd:COG5009 615 WDGAeprlpdpaeQVIDPRTAYQMTSMLRGVVQRGTGRRARALG--------------RDIAGKTGTTNDSKDAWFVGFT 680
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 684 PYYTSVFWFGFDKPgQSLGLQLTGSTLSGYAWADYMKKIHNGLPMKDFSKPAtGVIEATVCSVSGGILTPECGDhKVTAW 763
Cdd:COG5009 681 PDLVAGVWVGFDDP-RSLGRGETGGRAALPIWIDFMKAALKDKPEKPFPVPE-GIVTVRIDPKTGLLASPGDPD-AIFEA 757
|
810 820
....*....|....*....|....*...
gi 2540503203 764 YLEGTQPTQVCSVHSTANSSRAI--GIY 789
Cdd:COG5009 758 FKPGTEPTESASEDLGPDASEGTgeGLF 785
|
|
| PBP_1a_fam |
TIGR02074 |
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan ... |
68-723 |
0e+00 |
|
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273955 [Multi-domain] Cd Length: 531 Bit Score: 563.81 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 68 KREIISIRDLPQCMLDALITREDRLFYSHHGYSVKALFRAVFGKLT-GMSLGGGSTLTQQIAGTLFCDrTDMSIRRKLKE 146
Cdd:TIGR02074 1 RREYVPIDDIPENLINAFLAIEDRRFYDHFGIDLKGIGRAAVANITsGRVLEGGSTITQQLAKNLYLT-NERTITRKIQE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 147 LWWAIQMERRYTKDEILELYLNKIYFGGGTYGVSAASKYYFGHDATEITPAEAAILVIQLSNPAFYNPFEYPNRAMDRQK 226
Cdd:TIGR02074 80 ALLALKLEQKLSKDEILELYLNRIYFGNGAYGIEAAAQFYFGKSVNDLTLAEAAMLAGLPKAPSAYNPFKNPERAKDRRN 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 227 DVLSTMVSAGYISKEQADESFDDYWANFDYTRTATAavfnhdDNAPWFSEYVRRELGNlIYGtEDIYSSGFTVNTTLNLK 306
Cdd:TIGR02074 160 LVLSNMVENGYITAEEAEEAINEPIQLYLQTKKSEQ------YKAPYFVDYVIQELEE-EYG-EELYTGGLKIYTTLDLD 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 307 NQAVAQDVMDRYIRYANRTYqrstgertnqafsvytpmtellaltfnlnslkvseqrneaiskatytsqinpvmdvmslm 386
Cdd:TIGR02074 232 AQKAAEKVLNTGLRVAGRRD------------------------------------------------------------ 251
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 387 fgvdslklgivnkanqqakvkvsKTTIEGTMIALENDTGYITSLVGGSKFdSENQFIRAVQAKLQPGSAFKPLYYSAAID 466
Cdd:TIGR02074 252 -----------------------GDDLQAALVAIDPDTGAVRALVGGRDY-GKSQFNRATQAKRQPGSTFKPFVYAAALE 307
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 467 SrKFTPTSIISDTPVVFHTADgkPYIPQNFRGEWKGDVELWYALAHSMNVPSLKVLDGIGFEAGInRSIALLGIPKEEVP 546
Cdd:TIGR02074 308 K-GLTPATIVNDEPITYNGNG--PWSPKNYGGGYRGNVTLRQALAQSRNIPAVRLLQEVGLDKVV-ALAKRFGITSPLDP 383
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 547 YrgfvpgYPIGLGVCSVRPVELARAYSVFASGGKEVTPIAIRSVEDKNGNVILnpekelrtalQAKGAAAQVISPQTAFV 626
Cdd:TIGR02074 384 V------LSLALGTVEVSPLEMASAYAVFANGGKYVEPHGIRKIVDRDGKVIY----------ENKPKTTQVISPATAYI 447
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 627 MTELLQNTVRSGTLAGPSsngdklrykdsnghLYKIPAAGKTGTTQNWADAWAVGFTPYYTSVFWFGFDKPGqSLGLQLT 706
Cdd:TIGR02074 448 MTDMLKGVVESGTGRSAR--------------LPGRPVAGKTGTTQNWRDAWFVGYTPYYVTAVWVGYDDKK-TLGKSGT 512
|
650
....*....|....*..
gi 2540503203 707 GSTLSGYAWADYMKKIH 723
Cdd:TIGR02074 513 GGGLAAPIWRDFMAEAL 529
|
|
| mrcA |
PRK11636 |
penicillin-binding protein 1a; Provisional |
1-777 |
1.59e-83 |
|
penicillin-binding protein 1a; Provisional
Pssm-ID: 183248 [Multi-domain] Cd Length: 850 Bit Score: 285.49 E-value: 1.59e-83
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 1 MKIKKstYVFVcgLFFCAIFFGAG--LGLalsnTKFIK----DNEQFTEFSTSLPTKLLDINGELITELAseEKREI-IS 73
Cdd:PRK11636 1 MKFVK--YLLI--LAVCCILLGAGsiYGL----YRYIEpqlpDVATLKDVRLQTPMQVYSADGELIAQYG--EKRRIpLT 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 74 IRDLPQCMLDALITREDRLFYSHHGYSVKALFRAVFGKLT-GMSLGGGSTLTQQIAGTLFC--DRTDMsirRKLKELWWA 150
Cdd:PRK11636 71 LDQIPPEMVKAFIATEDSRFYEHHGVDPVGIFRAASVALFsGHASQGASTITQQLARNFFLspERTLM---RKIKEAFLA 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 151 IQMERRYTKDEILELYLNKIYFGGGTYGVSAASKYYFGHDATEITPAEAAILVIQLSNPAFYNPFEYPNRAMDRQKDVLS 230
Cdd:PRK11636 148 IRIEQLLTKDEILELYLNKIYLGYRAYGVGAAAQVYFGKTVDQLTLSEMAVIAGLPKAPSTFNPLYSMDRAVARRNVVLS 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 231 TMVSAGYISKEQADESFDDYW-ANFDytrtATAAVFnhddNAPWFSEYVRRELGNLiYGtEDIYSSGFTVNTTLNLKNQA 309
Cdd:PRK11636 228 RMLDEGYITQAQYDQARSEPIvANYH----APEIAF----SAPYLSEMVRQEMYNR-YG-ENAYEDGYRVYTTITRKVQQ 297
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 310 VAQD-----VMDRYIRYANRTYQR---STGER---------TNQAFSVYTPMtellaltfnLNSLKVSEQRNEAISKATY 372
Cdd:PRK11636 298 AAQQavrnnVLDYDMRHGYRGPANvlwKVGESawdnkkitdTLKALPTYGPL---------LPAVVTSANPQEATAMLAD 368
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 373 TSQINPVMDVM--SLMFGVDSL------KLGIVNKANQQAKVKVSKTT--------IEGTMIALENDTGYITSLVGGSKF 436
Cdd:PRK11636 369 GSSVALPMEGVrwARPYRSDTQqgptprKVTDVVQTGQQIWVRQVDDAwwlaqvpdVNSALVSINPQNGAVMALVGGFDF 448
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 437 dSENQFIRAVQAKLQPGSAFKPLYYSAAIDsRKFTPTSIISDTPVVFHTAD-GKPYIPQNFRGEWKGDVELWYALAHSMN 515
Cdd:PRK11636 449 -NQSKFNRATQALRQVGSNIKPFLYTAAMD-KGLTLASMLNDVPISRWDAGaGSDWRPKNSPPQYAGPIRLRQGLGQSKN 526
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 516 VPSLKVLDGIGFEAGINrSIALLGIPKEEVpyrgfVPGYPIGLGVCSVRPVELARAYSVFASGGKEVTPIAIRSVEDKNG 595
Cdd:PRK11636 527 VVMVRAMRAMGVDYAAE-YLQRFGFPAQNI-----VHTESLALGSASFTPMQVARGYAVMANGGFLVDPYFISKIENDQG 600
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 596 NVILN--------------------------------------------PEKELRTALQAKGA-------AAQVISPQTA 624
Cdd:PRK11636 601 GVIFEakpkvacpecdipviygdtqksnvlenddvenvatsqeqqnssvPMPQLEQANQALVAqngaqeyAPHVINTPLA 680
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 625 FVMTELLQNTV--RSGTLAGPSSNGDKLRYKDsnghlykipAAGKTGTTQNWADAWAVGFTPYYTSVFWFGFDKPGQSLG 702
Cdd:PRK11636 681 FLIKSALNTNIfgEPGWMGTGWRAGRDLKRRD---------IGGKTGTTNSSKDAWFSGYGPGVVTSVWIGFDDHRRDLG 751
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 703 lQLTGS-----TLSGY---------AWADYMKKIHNGLPMKDFSKPAtGVIEATVCSVSGGILTpecGDHKVTAWYLEGT 768
Cdd:PRK11636 752 -RTTASgaikdQISGYeggaksaqpAWDDYMKAALEGVPEQPLTPPP-GIVTVNIDRSTGKLAN---GGNSREEYFIEGT 826
|
....*....
gi 2540503203 769 QPTQVcSVH 777
Cdd:PRK11636 827 QPTQQ-AVH 834
|
|
| Transgly |
pfam00912 |
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of ... |
56-233 |
1.19e-71 |
|
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of transglycosylase and transpeptidase in the N- and C-terminus respectively. The transglycosylase domain catalyzes the polymerization of murein glycan chains.
Pssm-ID: 459993 [Multi-domain] Cd Length: 177 Bit Score: 233.18 E-value: 1.19e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 56 NGELITELaSEEKREIISIRDLPQCMLDALITREDRLFYSHHGYSVKALFRAVFGKLTGMSL-GGGSTLTQQIAGTLFcD 134
Cdd:pfam00912 1 DGTLLAEL-GEENREYVPLDDIPPALKNAVLAIEDRRFYEHGGVDPKGIARALLSNLRSGRIvQGGSTITQQLAKNLF-L 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 135 RTDMSIRRKLKELWWAIQMERRYTKDEILELYLNKIYFGGGTYGVSAASKYYFGHDATEITPAEAAILVIQLSNPAFYNP 214
Cdd:pfam00912 79 TPERTLTRKLKEAVLALKLERRYSKDEILEAYLNTVYFGRGAYGIEAAARAYFGKDASDLTLAEAALLAGLPQAPSRYNP 158
|
170
....*....|....*....
gi 2540503203 215 FEYPNRAMDRQKDVLSTMV 233
Cdd:pfam00912 159 LRNPERAKRRRNLVLDRMV 177
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| MrcA |
COG5009 |
Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis]; |
1-789 |
0e+00 |
|
Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 444033 [Multi-domain] Cd Length: 785 Bit Score: 666.09 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 1 MKIKKstYVFVCGLFFCAIFFGAGLGLALSNTKFIKDNEQFTEFSTSLPTKLLDINGELITELAsEEKREIISIRDLPQC 80
Cdd:COG5009 1 MRLLK--ILLILLLLLLLLGALAVAGLYLYLSPDLPDVETLKDYQPPTPSRVYSADGKLIAEFG-EERRIPVPIEEIPPL 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 81 MLDALITREDRLFYSHHGYSVKALFRAVFGKL-TGMSLGGGSTLTQQIAGTLFCDRtDMSIRRKLKELWWAIQMERRYTK 159
Cdd:COG5009 78 LINAFLAAEDKRFYEHPGVDPIGIARAAVVNLrTGRRVQGGSTITQQVAKNFLLSP-ERTLTRKIKEAILALRIEQELSK 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 160 DEILELYLNKIYFGGGTYGVSAASKYYFGHDATEITPAEAAILVIQLSNPAFYNPFEYPNRAMDRQKDVLSTMVSAGYIS 239
Cdd:COG5009 157 DEILELYLNKIYLGHRAYGVAAAAQTYFGKSLDELTLAEAAMLAGLPKAPSRYNPIRNPERALERRNYVLGRMLELGYIT 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 240 KEQADESFDdywANFDYTRTATAAvfnhDDNAPWFSEYVRRELGNLiYGTEDIYSSGFTVNTTLNLKNQAVAQDVMDRY- 318
Cdd:COG5009 237 QAEYEAAKA---EPLTARYHGASA----EVDAPYFAEMVRRELVER-YGEDALYTGGLKVYTTLDPRLQEAAEKALRDGl 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 319 IRYANRTYQRSTGERTNQAFSvytPMTELLALTFNLNS------LKVSEQRNEAISKATYTSQINpvMDVMSLM--FGVD 390
Cdd:COG5009 309 LAYDRRHGYRGPEAHLDLAEE---DWDEALAEVPDVGDlrpavvLEVDDKSARVGLRDGETGTLP--LEGLKWArpYIND 383
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 391 SLKLGIVNKANQQAK----VKVSKTT-----------IEGTMIALENDTGYITSLVGGSKFDsENQFIRAVQAKLQPGSA 455
Cdd:COG5009 384 NRRGPAPKSASDVLKpgdvIRVRPVAdggwrlrqipeVQGALVALDPHTGAVLALVGGFDFE-QSKFNRATQAKRQPGSS 462
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 456 FKPLYYSAAIDsRKFTPTSIISDTPVVFHT-ADGKPYIPQNFRGEWKGDVELWYALAHSMNVPSLKVLDGIGFEAGINRs 534
Cdd:COG5009 463 FKPFVYAAALD-NGYTPATIINDAPIVFDDgGGGGVWRPKNYSGKFYGPTTLREALEKSRNLVTVRLLQDVGIDYVIDY- 540
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 535 IALLGIPKEevpyrgFVPGYPIGLGVCSVRPVELARAYSVFASGGKEVTPIAIRSVEDKNGNVIL--NPEKELRTALQAK 612
Cdd:COG5009 541 AERFGIYSK------LPPNLSLALGSGEVTPLEMARAYAVFANGGYRVEPYLIDRIEDRNGKVIYraDPARACEDCDAAE 614
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 613 GAAA---------QVISPQTAFVMTELLQNTVRSGTLAGPSSNGdklrykdsnghlykIPAAGKTGTTQNWADAWAVGFT 683
Cdd:COG5009 615 WDGAeprlpdpaeQVIDPRTAYQMTSMLRGVVQRGTGRRARALG--------------RDIAGKTGTTNDSKDAWFVGFT 680
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 684 PYYTSVFWFGFDKPgQSLGLQLTGSTLSGYAWADYMKKIHNGLPMKDFSKPAtGVIEATVCSVSGGILTPECGDhKVTAW 763
Cdd:COG5009 681 PDLVAGVWVGFDDP-RSLGRGETGGRAALPIWIDFMKAALKDKPEKPFPVPE-GIVTVRIDPKTGLLASPGDPD-AIFEA 757
|
810 820
....*....|....*....|....*...
gi 2540503203 764 YLEGTQPTQVCSVHSTANSSRAI--GIY 789
Cdd:COG5009 758 FKPGTEPTESASEDLGPDASEGTgeGLF 785
|
|
| PBP_1a_fam |
TIGR02074 |
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan ... |
68-723 |
0e+00 |
|
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273955 [Multi-domain] Cd Length: 531 Bit Score: 563.81 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 68 KREIISIRDLPQCMLDALITREDRLFYSHHGYSVKALFRAVFGKLT-GMSLGGGSTLTQQIAGTLFCDrTDMSIRRKLKE 146
Cdd:TIGR02074 1 RREYVPIDDIPENLINAFLAIEDRRFYDHFGIDLKGIGRAAVANITsGRVLEGGSTITQQLAKNLYLT-NERTITRKIQE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 147 LWWAIQMERRYTKDEILELYLNKIYFGGGTYGVSAASKYYFGHDATEITPAEAAILVIQLSNPAFYNPFEYPNRAMDRQK 226
Cdd:TIGR02074 80 ALLALKLEQKLSKDEILELYLNRIYFGNGAYGIEAAAQFYFGKSVNDLTLAEAAMLAGLPKAPSAYNPFKNPERAKDRRN 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 227 DVLSTMVSAGYISKEQADESFDDYWANFDYTRTATAavfnhdDNAPWFSEYVRRELGNlIYGtEDIYSSGFTVNTTLNLK 306
Cdd:TIGR02074 160 LVLSNMVENGYITAEEAEEAINEPIQLYLQTKKSEQ------YKAPYFVDYVIQELEE-EYG-EELYTGGLKIYTTLDLD 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 307 NQAVAQDVMDRYIRYANRTYqrstgertnqafsvytpmtellaltfnlnslkvseqrneaiskatytsqinpvmdvmslm 386
Cdd:TIGR02074 232 AQKAAEKVLNTGLRVAGRRD------------------------------------------------------------ 251
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 387 fgvdslklgivnkanqqakvkvsKTTIEGTMIALENDTGYITSLVGGSKFdSENQFIRAVQAKLQPGSAFKPLYYSAAID 466
Cdd:TIGR02074 252 -----------------------GDDLQAALVAIDPDTGAVRALVGGRDY-GKSQFNRATQAKRQPGSTFKPFVYAAALE 307
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 467 SrKFTPTSIISDTPVVFHTADgkPYIPQNFRGEWKGDVELWYALAHSMNVPSLKVLDGIGFEAGInRSIALLGIPKEEVP 546
Cdd:TIGR02074 308 K-GLTPATIVNDEPITYNGNG--PWSPKNYGGGYRGNVTLRQALAQSRNIPAVRLLQEVGLDKVV-ALAKRFGITSPLDP 383
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 547 YrgfvpgYPIGLGVCSVRPVELARAYSVFASGGKEVTPIAIRSVEDKNGNVILnpekelrtalQAKGAAAQVISPQTAFV 626
Cdd:TIGR02074 384 V------LSLALGTVEVSPLEMASAYAVFANGGKYVEPHGIRKIVDRDGKVIY----------ENKPKTTQVISPATAYI 447
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 627 MTELLQNTVRSGTLAGPSsngdklrykdsnghLYKIPAAGKTGTTQNWADAWAVGFTPYYTSVFWFGFDKPGqSLGLQLT 706
Cdd:TIGR02074 448 MTDMLKGVVESGTGRSAR--------------LPGRPVAGKTGTTQNWRDAWFVGYTPYYVTAVWVGYDDKK-TLGKSGT 512
|
650
....*....|....*..
gi 2540503203 707 GSTLSGYAWADYMKKIH 723
Cdd:TIGR02074 513 GGGLAAPIWRDFMAEAL 529
|
|
| MrcB |
COG0744 |
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall ... |
9-735 |
0e+00 |
|
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440507 [Multi-domain] Cd Length: 630 Bit Score: 547.98 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 9 VFVCGLFFCAIFFGAGLGLALSNTKFIKDNEQFTEFSTSLPTKLLDINGELITELaSEEKREIISIRDLPQCMLDALITR 88
Cdd:COG0744 15 LGLLLLLLAVLVLAALAGLVALYVADLPDPEELEDLALPQTSTIYDRDGTLIATL-GDENREWVPLDQIPPHLKDAVVAI 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 89 EDRLFYSHHGYSVKALFRAVFGKLTGMS-LGGGSTLTQQIAGTLFCDrTDMSIRRKLKELWWAIQMERRYTKDEILELYL 167
Cdd:COG0744 94 EDRRFYEHGGVDPKGIARALVANLTAGGvVQGGSTITQQLVKNLFLS-NERTLSRKLKEALLALKLERKYSKDEILELYL 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 168 NKIYFGGGTYGVSAASKYYFGHDATEITPAEAAILVIQLSNPAFYNPFEYPNRAMDRQKDVLSTMVSAGYISKEQADEsf 247
Cdd:COG0744 173 NTVYFGRGAYGIEAAAQYYFGKSASDLTLAEAALLAGLVKAPSYYDPYRNPEAAKERRNLVLDRMVEQGYITQAEADA-- 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 248 ddyWANFDYTRTATAAVFNhDDNAPWFSEYVRRELGNLiYGTEDIYSSGFTVNTTLNLKNQAVAQDVMDRYIRyanrtyq 327
Cdd:COG0744 251 ---AKAEPLTLVPPPNGAA-AGKYPYFVDYVRRELEEL-LGEDDLYRGGLKIYTTLDPKLQKAAEKAVKNVLP------- 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 328 rstgertnqafsvytpmtellaltfnlnslkvseqrneaiskatytsqinpvmdvmslmfgvdslklgivnkanqqakvK 407
Cdd:COG0744 319 -------------------------------------------------------------------------------E 319
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 408 VSKTTIEGTMIALENDTGYITSLVGGSKFdSENQFIRAVQAKLQPGSAFKPLYYSAAIDsRKFTPTSIISDTPVVFhtaD 487
Cdd:COG0744 320 GKPGGLQAALVVVDPKTGEVLAMVGGRDY-GKSQFNRATQAKRQPGSTFKPFVYAAALE-QGYTPATTVDDEPVTF---P 394
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 488 GKPYIPQNFRGEWKGDVELWYALAHSMNVPSLKVLDGIGFEAGINRSIAlLGIPKEEVPYRGFVpgypigLGVCSVRPVE 567
Cdd:COG0744 395 GGGWSPKNYDGRYRGPVTLREALANSLNTPAVRLAQEVGLDKVVDTARR-LGITSPLDPNPSLA------LGTSEVSPLE 467
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 568 LARAYSVFASGGKEVTPIAIRSVEDKNGNVILNPEKELRtalqakgaaaQVISPQTAFVMTELLQNTVRSGTlagpssnG 647
Cdd:COG0744 468 MASAYATFANGGVYVEPHAITKVTDADGKVLYEAKPKCE----------QVISPEVAYLMTDMLQDVVTSGT-------G 530
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 648 DKLRYKDsnghlykIPAAGKTGTTQNWADAWAVGFTPYYTSVFWFGFDKpGQSLGLqLTGSTLSGYAWADYMKKIHNGLP 727
Cdd:COG0744 531 RAARLPG-------RPVAGKTGTTNDNRDAWFVGYTPQLVTAVWVGNDD-NSPMGY-VTGGSLPAPIWRDFMEAALEGLP 601
|
....*...
gi 2540503203 728 MKDFSKPA 735
Cdd:COG0744 602 VEDFPKPS 609
|
|
| PbpC |
COG4953 |
Membrane carboxypeptidase/penicillin-binding protein PbpC [Cell wall/membrane/envelope ... |
1-787 |
1.01e-96 |
|
Membrane carboxypeptidase/penicillin-binding protein PbpC [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 443980 [Multi-domain] Cd Length: 773 Bit Score: 319.47 E-value: 1.01e-96
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 1 MKIKKSTYVFVCGLFFCAIFFGAGLGLALSNtkFIKDNEQFTEFSTSLptklLDINGELI-TELASEEK-REIISIRDLP 78
Cdd:COG4953 1 MKRARLRRRRLLALLLALLLLALALWALDRL--FPLPLLFAVPYSTVV----LDRDGTLLrAFLAADGQwRLPVPLDEVS 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 79 QCMLDALITREDRLFYSHHGYSVKALFRAVFGKLTG---MSlgGGSTLTQQIAGTLfcDRTDMSIRRKLKELWWAIQMER 155
Cdd:COG4953 75 PRYLQALLAYEDRRFYYHPGVNPLALLRAAWQNLRSgriVS--GGSTLTMQVARLL--EPRPRTLSGKLRQILRALQLER 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 156 RYTKDEILELYLNKIYFGGGTYGVSAASKYYFGHDATEITPAEAAILVIQLSNPAFYNPFEYPNRAMDRQKDVLSTMVSA 235
Cdd:COG4953 151 RYSKDEILELYLNLAPYGGNIEGVEAASLAYFGKPPSRLSLAEAALLAVLPQAPSRRRPDRNPERARAARDRVLARLAEA 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 236 GYISKEQADESFDDY-WAnfdyTRTATAAVfnhddnAPWFSEYVRRElgnliygtediYSSGFTVNTTLNLKNQAVAQDV 314
Cdd:COG4953 231 GVIDAEEAALALLEPvPA----RRRPLPQL------APHLARRLLRQ-----------LPGGTRIRTTLDAGLQRRLERL 289
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 315 MDRYIRyanrtyQRSTGERTNQAfsvytpmtellaltfnlnslkvseqrneaiskatytsqinpvmdvmslmfgvdslkl 394
Cdd:COG4953 290 VRRYVR------RLKQNGIHNAA--------------------------------------------------------- 306
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 395 givnkanqqakvkvskttiegtMIALENDTGYITSLVGGSKF-DSENQ-FIRAVQAKLQPGSAFKPLYYSAAIDSRKFTP 472
Cdd:COG4953 307 ----------------------VLVVDNRTGEVLAYVGSADFfDASRQgQVDMVRALRSPGSTLKPFLYGLALDQGLIHP 364
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 473 TSIISDTPVVFhtadgKPYIPQNFRGEWKGDVELWYALAHSMNVPSLKVLDgigfEAGINRSIALL---GI----PKEEv 545
Cdd:COG4953 365 ETLLADVPTSF-----GGYRPENFDGTFQGPVSAREALARSLNIPAVRLLE----ALGPARFYARLrraGLrlllPPAE- 434
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 546 pyrgfVPGYPIGLGVCSVRPVELARAYSVFASGGkEVTPiairsvedkngnvilnpekeLR-TALQAKGAAAQVISPQTA 624
Cdd:COG4953 435 -----HYGLSLILGGAEVTLEELVGLYAALARGG-EARP--------------------LRlLAGEPASPGRRLLSPGAA 488
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 625 FVMTELLQNTVRSGTLAGPSSNGDKLrykdsnghlykiPAAGKTGTTQNWADAWAVGFTPYYTSVFWFG-FD---KPGqs 700
Cdd:COG4953 489 WLVRDILSDVPRPDGAFGWRALDSPP------------PIAWKTGTSYGFRDAWAVGFTGRYTVGVWVGnPDgtpVPG-- 554
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 701 lglqLTGSTLSGYAWADYMKKIHNGLPMKDFSKPAtGVIEATVCSVSGGILTPECgDHKVTAWYLEGTQPTQVCSVHSTA 780
Cdd:COG4953 555 ----LTGAEAAAPLLFDIFDLLPASRWPLPFPPPA-GLLRVEVCAPSGLLAGPNC-PQRVTEWFIPGTSPPTLCPYHQLV 628
|
....*..
gi 2540503203 781 NSSRAIG 787
Cdd:COG4953 629 WVDAATG 635
|
|
| PBP_1b |
TIGR02071 |
penicillin-binding protein 1B; Bacterial that synthesize a cell wall of peptidoglycan (murein) ... |
59-756 |
1.09e-89 |
|
penicillin-binding protein 1B; Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of a particular bifunctional transglycosylase/transpeptidase in E. coli and other Proteobacteria, designated penicillin-binding protein 1B. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273952 [Multi-domain] Cd Length: 730 Bit Score: 299.71 E-value: 1.09e-89
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 59 LITELASE--EKREIISIRDLPQCMLDALITREDRLFYSHHGYSVKALFRAVFGKLT-GMSLGGGSTLTQQIAGTLFCDR 135
Cdd:TIGR02071 135 LIAMLYSPngEQRLFVPRDQFPELLVDTLLATEDRDFYEHDGISLYSIGRAVWVNLTaGRTVQGGSTLTQQLVKNLFLSN 214
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 136 tDMSIRRKLKELWWAIQMERRYTKDEILELYLNKIYFG--GGT--YGVSAASKYYFGHDATEITPAEAAILVIQLSNPAF 211
Cdd:TIGR02071 215 -ERSLWRKANEAYMALILDARYSKDRILELYLNEVYLGqsGDDaiHGFPLASQYYFGRPLGELSLDQVALLVGMVKGPSY 293
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 212 YNPFEYPNRAMDRQKDVLSTMVSAGYISkeqaDESFDDYWAN-FDYTRTATAAvfnhdDNAPWFSEYVRRELGNLiYGTE 290
Cdd:TIGR02071 294 YNPWRNPDRALERRNLVLRLLQEQKIID----DEEYDMLSARpLGVQKKGGII-----SRQPAFLQLVRRELRQK-LGDK 363
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 291 DIYSSGFTVNTTLNLKNQAVAqdvmdryiryanrtyQRSTGERTNQafsvytpmtelLALTFNLNSLkvseqrneaiska 370
Cdd:TIGR02071 364 VKDLSGLRIFTTLDPVSQSAA---------------EQAVQETIPA-----------LKKKKKLPDL------------- 404
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 371 tytsqinpvmdvmslmfgvdslklgivnkanqqakvkvskttiEGTMIALENDTGYITSLVGGSKfDSENQFIRAVQAKL 450
Cdd:TIGR02071 405 -------------------------------------------EAAMVVTDRFTGEVRAMVGGSD-PQFAGFNRALQARR 440
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 451 QPGSAFKPLYYSAAIDS-RKFTPTSIISDTPVVFHTADGKPYIPQNFRGEWKGDVELWYALAHSMNVPSLKVLDGIGFEA 529
Cdd:TIGR02071 441 QIGSLVKPAVYLTALSQpDKYRLNTWIEDQPLSIKLSNGQVWSPQNYDRRYSGTVMLYDALAHSLNIPTVNLGMKVGLPK 520
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 530 gINRSIALLGIPKEEVPYrgfVPGypIGLGVCSVRPVELARAYSVFASGGKEVTPIAIRSVEDKNGNVIlnpekelrtaL 609
Cdd:TIGR02071 521 -VSQTWNKLGINKDEIPP---VPS--MLLGAINLTPYEVAQLYQTIASGGNRAPLSAVRSVLDEDGKVL----------Y 584
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 610 QAKGAAAQVISPQTAFVMTELLQNTVRSGTlagpssnGDKLRYKDSNGHLykipaAGKTGTTQNWADAWAVGFTPYYTSV 689
Cdd:TIGR02071 585 QSDPQAEQAVPSQAAYLTLYAMQQVVQRGT-------ARSLGADFPSLSL-----AGKTGTTNDNRDSWFAGIDGKEVTI 652
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2540503203 690 FWFGFDKPGQSlglQLTGSTLSGYAWADYMKKIHnglPMKDFSKPATGVIEATVCSVSGGILTPECG 756
Cdd:TIGR02071 653 IWLGRDDNGPT---KLTGASGALQVYARYLSYQT---PEPLLLVPPEGIDWFGVDPQGNGGCKANCP 713
|
|
| mrcA |
PRK11636 |
penicillin-binding protein 1a; Provisional |
1-777 |
1.59e-83 |
|
penicillin-binding protein 1a; Provisional
Pssm-ID: 183248 [Multi-domain] Cd Length: 850 Bit Score: 285.49 E-value: 1.59e-83
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 1 MKIKKstYVFVcgLFFCAIFFGAG--LGLalsnTKFIK----DNEQFTEFSTSLPTKLLDINGELITELAseEKREI-IS 73
Cdd:PRK11636 1 MKFVK--YLLI--LAVCCILLGAGsiYGL----YRYIEpqlpDVATLKDVRLQTPMQVYSADGELIAQYG--EKRRIpLT 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 74 IRDLPQCMLDALITREDRLFYSHHGYSVKALFRAVFGKLT-GMSLGGGSTLTQQIAGTLFC--DRTDMsirRKLKELWWA 150
Cdd:PRK11636 71 LDQIPPEMVKAFIATEDSRFYEHHGVDPVGIFRAASVALFsGHASQGASTITQQLARNFFLspERTLM---RKIKEAFLA 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 151 IQMERRYTKDEILELYLNKIYFGGGTYGVSAASKYYFGHDATEITPAEAAILVIQLSNPAFYNPFEYPNRAMDRQKDVLS 230
Cdd:PRK11636 148 IRIEQLLTKDEILELYLNKIYLGYRAYGVGAAAQVYFGKTVDQLTLSEMAVIAGLPKAPSTFNPLYSMDRAVARRNVVLS 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 231 TMVSAGYISKEQADESFDDYW-ANFDytrtATAAVFnhddNAPWFSEYVRRELGNLiYGtEDIYSSGFTVNTTLNLKNQA 309
Cdd:PRK11636 228 RMLDEGYITQAQYDQARSEPIvANYH----APEIAF----SAPYLSEMVRQEMYNR-YG-ENAYEDGYRVYTTITRKVQQ 297
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 310 VAQD-----VMDRYIRYANRTYQR---STGER---------TNQAFSVYTPMtellaltfnLNSLKVSEQRNEAISKATY 372
Cdd:PRK11636 298 AAQQavrnnVLDYDMRHGYRGPANvlwKVGESawdnkkitdTLKALPTYGPL---------LPAVVTSANPQEATAMLAD 368
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 373 TSQINPVMDVM--SLMFGVDSL------KLGIVNKANQQAKVKVSKTT--------IEGTMIALENDTGYITSLVGGSKF 436
Cdd:PRK11636 369 GSSVALPMEGVrwARPYRSDTQqgptprKVTDVVQTGQQIWVRQVDDAwwlaqvpdVNSALVSINPQNGAVMALVGGFDF 448
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 437 dSENQFIRAVQAKLQPGSAFKPLYYSAAIDsRKFTPTSIISDTPVVFHTAD-GKPYIPQNFRGEWKGDVELWYALAHSMN 515
Cdd:PRK11636 449 -NQSKFNRATQALRQVGSNIKPFLYTAAMD-KGLTLASMLNDVPISRWDAGaGSDWRPKNSPPQYAGPIRLRQGLGQSKN 526
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 516 VPSLKVLDGIGFEAGINrSIALLGIPKEEVpyrgfVPGYPIGLGVCSVRPVELARAYSVFASGGKEVTPIAIRSVEDKNG 595
Cdd:PRK11636 527 VVMVRAMRAMGVDYAAE-YLQRFGFPAQNI-----VHTESLALGSASFTPMQVARGYAVMANGGFLVDPYFISKIENDQG 600
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 596 NVILN--------------------------------------------PEKELRTALQAKGA-------AAQVISPQTA 624
Cdd:PRK11636 601 GVIFEakpkvacpecdipviygdtqksnvlenddvenvatsqeqqnssvPMPQLEQANQALVAqngaqeyAPHVINTPLA 680
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 625 FVMTELLQNTV--RSGTLAGPSSNGDKLRYKDsnghlykipAAGKTGTTQNWADAWAVGFTPYYTSVFWFGFDKPGQSLG 702
Cdd:PRK11636 681 FLIKSALNTNIfgEPGWMGTGWRAGRDLKRRD---------IGGKTGTTNSSKDAWFSGYGPGVVTSVWIGFDDHRRDLG 751
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 703 lQLTGS-----TLSGY---------AWADYMKKIHNGLPMKDFSKPAtGVIEATVCSVSGGILTpecGDHKVTAWYLEGT 768
Cdd:PRK11636 752 -RTTASgaikdQISGYeggaksaqpAWDDYMKAALEGVPEQPLTPPP-GIVTVNIDRSTGKLAN---GGNSREEYFIEGT 826
|
....*....
gi 2540503203 769 QPTQVcSVH 777
Cdd:PRK11636 827 QPTQQ-AVH 834
|
|
| PBP_1c |
TIGR02073 |
penicillin-binding protein 1C; This subfamily of the penicillin binding proteins includes the ... |
50-777 |
3.63e-77 |
|
penicillin-binding protein 1C; This subfamily of the penicillin binding proteins includes the member from E. coli designated penicillin-binding protein 1C. Members have both transglycosylase and transpeptidase domains and are involved in forming cross-links in the late stages of peptidoglycan biosynthesis. All members of this subfamily are presumed to have the same basic function. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273954 [Multi-domain] Cd Length: 727 Bit Score: 265.44 E-value: 3.63e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 50 TKLLDINGELI-TELASEEKREI-ISIRDLPQCMLDALITREDRLFYSHHGYSVKALFRAVFGKLT-GMSLGGGSTLTQQ 126
Cdd:TIGR02073 12 TVVLDRHGTLLrALLANDGQWRLpVPLEDISPKFLQALLLYEDKRFYWHPGVNPLALLRAAWQNLTnGRRVSGGSTLTMQ 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 127 IAGtLFCDRTDMSIRRKLKELWWAIQMERRYTKDEILELYLNKIYFGGGTYGVSAASKYYFGHDATEITPAEAAILVIQL 206
Cdd:TIGR02073 92 LAR-LLDPELSRTLTGKLRQMWRAIQLEARYSKREILEAYLNLAPYGGNLEGLRAASLIYFGKEPSSLSLAEAALLAALP 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 207 SNPAFYNPFEYPNRAMDRQKDVLSTMVSAGYISKEQADESfddywanfdytrtATAAVFNHDDNAPWFSEYVRRElgnLI 286
Cdd:TIGR02073 171 QAPSARRLDRLPKAAKAARDRLLDRMVEQGPDDSEQVALA-------------ALEPLPALPEPLPQLAPHFALK---LL 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 287 YGTEDIYSsgfTVNTTLNLKNQAVAQDVMDRYIrYANRtyqrstgertnqafsvytpmtellaltfnlnslkvseqrnea 366
Cdd:TIGR02073 235 RARPEIAS---VIVSTLDADLQRRLEELARRYL-SALR------------------------------------------ 268
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 367 iskatytsqinpvmdvmslmfgvdslKLGIVNKAnqqakvkvskttiegtMIALENDTGYITSLVGGSKFDSENQF--IR 444
Cdd:TIGR02073 269 --------------------------PRGISNLA----------------ILVVDNRSGAVLAYVGSADFFDDSNSgqVD 306
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 445 AVQAKLQPGSAFKPLYYSAAIDSRKFTPTSIISDTPVVFHTadgkpYIPQNFRGEWKGDVELWYALAHSMNVPSLKVLDG 524
Cdd:TIGR02073 307 GVRAPRSPGSTLKPFLYALALDDGLLHPDSLLKDVPLRFGD-----YAPENFDKTFHGPVPAREALARSLNIPAVRLLER 381
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 525 IGFE--AGINRSIALLGIPKEevpyrGFVPGYPIGLGVCSVRPVELARAYSVFASGGkevtpiairsvedkngnvILNPE 602
Cdd:TIGR02073 382 VGPPrfADFLRQAGLNLLKPK-----SDYYGLSLALGGAEITLQDLANLYAMLANQG------------------LSGPL 438
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 603 KELRTaLQAKGAAAQVISPQTAFVMTELLQNTVRSGTLAGPSSNGDKLrykdsnghlykiPAAGKTGTTQNWADAWAVGF 682
Cdd:TIGR02073 439 RFLQT-DAKRPERERLLSPGAAWIVLDILKDRPRPDDTLPLSALPTRL------------PLAWKTGTSYGFRDAWAAGV 505
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 683 TPYYTSVFWFG-FD---KPGqslglqLTGSTLSGYAWADymkkIHNGLPMKDFSKPATGVIEATVCSVSGGILTPECgDH 758
Cdd:TIGR02073 506 SGRYTIGVWVGnFDgkpNPG------FFGAAAAAPLLFD----ILDALQASEASTLPRPLKEVPGCLVLGNLPILPC-PE 574
|
730
....*....|....*....
gi 2540503203 759 KVTAWYLEGTQPTQVCSVH 777
Cdd:TIGR02073 575 QISTWFLPGGSPPTLSEPH 593
|
|
| Transgly |
pfam00912 |
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of ... |
56-233 |
1.19e-71 |
|
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of transglycosylase and transpeptidase in the N- and C-terminus respectively. The transglycosylase domain catalyzes the polymerization of murein glycan chains.
Pssm-ID: 459993 [Multi-domain] Cd Length: 177 Bit Score: 233.18 E-value: 1.19e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 56 NGELITELaSEEKREIISIRDLPQCMLDALITREDRLFYSHHGYSVKALFRAVFGKLTGMSL-GGGSTLTQQIAGTLFcD 134
Cdd:pfam00912 1 DGTLLAEL-GEENREYVPLDDIPPALKNAVLAIEDRRFYEHGGVDPKGIARALLSNLRSGRIvQGGSTITQQLAKNLF-L 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 135 RTDMSIRRKLKELWWAIQMERRYTKDEILELYLNKIYFGGGTYGVSAASKYYFGHDATEITPAEAAILVIQLSNPAFYNP 214
Cdd:pfam00912 79 TPERTLTRKLKEAVLALKLERRYSKDEILEAYLNTVYFGRGAYGIEAAARAYFGKDASDLTLAEAALLAGLPQAPSRYNP 158
|
170
....*....|....*....
gi 2540503203 215 FEYPNRAMDRQKDVLSTMV 233
Cdd:pfam00912 159 LRNPERAKRRRNLVLDRMV 177
|
|
| PRK14850 |
PRK14850 |
penicillin-binding protein 1b; Provisional |
52-729 |
1.05e-65 |
|
penicillin-binding protein 1b; Provisional
Pssm-ID: 237835 [Multi-domain] Cd Length: 764 Bit Score: 234.35 E-value: 1.05e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 52 LLDINGELITELASE--EKREIISIRDLPQCMLDALITREDRLFYSHHGYSVKALFRAVFGKL-TGMSLGGGSTLTQQIA 128
Cdd:PRK14850 138 FLRLDPKLIAMLYSPegKKRLFIPRNQYPEMLIKTLLAIEDKYFYEHDGIHLSSIGRAFLVNLmSGHTIQGGSTLTQQLV 217
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 129 GTLFCDRTdMSIRRKLKELWWAIQMERRYTKDEILELYLNKIYFGGG----TYGVSAASKYYFGHDATEITPAEAAILVI 204
Cdd:PRK14850 218 KNLFLTNT-RSLWRKINEIYMALILDRFYSKDRILELYLNEVYLGQDgneqIRGFPLASIYYFGRPINELNLDQYALLVG 296
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 205 QLSNPAFYNPFEYPNRAMDRQKDVLSTMVSAGYISKEQadesfddywanFDYTRTATAAVFNHDD---NAPWFSEYVRRE 281
Cdd:PRK14850 297 MVKGASLYNPWTNPNLTLKRRNLVLFLLYKQKVITRKL-----------YKDLCSRPLNVQSKGNiisSHPAFIQLVCEE 365
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 282 LGNLI-YGTEDIysSGFTVNTTLNLKNQAVAQDVMdryiryanrtyqrstgertnqafsvytpmtellaltfnlnslkvs 360
Cdd:PRK14850 366 FHKKIhYPFKNF--SGTKIFTTLDYISQNAAEQAV--------------------------------------------- 398
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 361 eqrneaiskatytsqinpvmdvmslmfgvdslKLGIvnkanQQAKVKVSKTTIEGTMIALENDTGYITSLVGGSKfDSEN 440
Cdd:PRK14850 399 --------------------------------KIGI-----PILKRKKRLKDLEVAMVIIDRFSGEVRALIGSSK-PEFN 440
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 441 QFIRAVQAKLQPGSAFKPLYYSAAIDS-RKFTPTSIISDTPVVFHTADGKPYIPQNFRGEWKGDVELWYALAHSMNVPSL 519
Cdd:PRK14850 441 GYNRALKARRSIGSLSKPITYLTALSQpEKYHLNTWISDTPISIKLDNGQYWTPKNNNFSFSGKVMLIDALIHSINIPTV 520
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 520 KVLDGIGFEAgINRSIALLGIPKEevpyrgFVPGYP-IGLGVCSVRPVELARAYSVFASGGKEVTPIAIRSVEDKNGNVI 598
Cdd:PRK14850 521 HLSINLGLKK-LVDSWILLGISSN------YITPLPsISLGAINLTPMEVAQVFQIIGSGGYKSSLSSIRSIISDDNKVL 593
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 599 lnpekelrtaLQAKGAAAQVISPQTAFVMTELLQNTVRSGTlagpssnGDKLRYKDSNGHLykipaAGKTGTTQNWADAW 678
Cdd:PRK14850 594 ----------YQNFPQSKHVESSQASYLTLYAMQQVVKSGT-------AKSLGTIFKEFSL-----AGKTGTTNNLVDSW 651
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|.
gi 2540503203 679 AVGFTPYYTSVFWFGFDKPGQSlglQLTGSTLSGYAWADYMkKIHNGLPMK 729
Cdd:PRK14850 652 FVGIDGKQVVITWIGRDNNHTT---KLYGSSGAMKIYKRYL-QYQNPVPLV 698
|
|
| mrcB |
PRK09506 |
bifunctional glycosyl transferase/transpeptidase; Reviewed |
59-743 |
3.94e-61 |
|
bifunctional glycosyl transferase/transpeptidase; Reviewed
Pssm-ID: 236544 [Multi-domain] Cd Length: 830 Bit Score: 222.34 E-value: 3.94e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 59 LITELASE--EKREIISIRDLPQCMLDALITREDRLFYSHHGYSVKALFRAVFGKLT-GMSLGGGSTLTQQIAGTLFCDr 135
Cdd:PRK09506 199 LITMLQSPngEQRLFVPRSGFPDLLVDTLLATEDRHFYEHDGISLYSIGRAVLANLTaGRTVQGGSTLTQQLVKNLFLS- 277
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 136 TDMSIRRKLKELWWAIQMERRYTKDEILELYLNKIYFG----GGTYGVSAASKYYFGHDATEITPAEAAILVIQLSNPAF 211
Cdd:PRK09506 278 NERSLWRKANEAYMALIMDARYSKDRILELYLNEVYLGqsgdDQIRGFPLASLYYFGRPVEELSLDQQALLVGMVKGASL 357
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 212 YNPFEYPNRAMDRQKDVLSTMVSAGYISKEQadesfddywanFDYTRTATAAVFNHDD---NAPWFSEYVRREL-GNLIY 287
Cdd:PRK09506 358 YNPWRNPKLALERRNLVLRLLQQQQIIDQEL-----------YDMLSARPLGVQPKGGvisPQPAFMQMVRQELqAKLGD 426
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 288 GTEDIysSGFTVNTTLNlknqAVAQDvmdryiryanrtyqrstgertnqafsvytpmtellaltfnlnslkvseqrneAI 367
Cdd:PRK09506 427 KVKDL--SGVKIFTTLD----PVSQD----------------------------------------------------AA 448
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 368 SKAtytsqinpVMDvmslmfGVDSLKlgivnkanQQAKVKvsktTIEGTMIALENDTGYITSLVGGSkfdsENQFI---R 444
Cdd:PRK09506 449 EKA--------VEE------GIPALK--------KQRKLS----DLETAMVVVDRFSGEVRAMVGGS----EPQFAgynR 498
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 445 AVQAKLQPGSAFKPLYYSAAIDS-RKFTPTSIISDTPVVFHTADGKPYIPQNFRGEWKGDVELWYALAHSMNVPSLKVLD 523
Cdd:PRK09506 499 AMQARRSIGSLAKPATYLTALSQpDKYRLNTWIADAPISLRQPNGQVWSPQNDDRRFSGRVMLVDALTRSMNVPTVNLGM 578
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 524 GIGFEAgINRSIALLGIPKEEVPYrgfVPGypIGLGVCSVRPVELARAYSVFASGGKEVTPIAIRSVEDKNGNVIlnpek 603
Cdd:PRK09506 579 ALGLPA-VTDTWIKLGVPKDQLNP---VPA--MLLGALNLTPIEVAQAFQTIASGGNRAPLSALRSVIAEDGKVL----- 647
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 604 elrtaLQAKGAAAQVISPQTAFVMTELLQNTVRSGTlagpssnGDKLRYKDSNGHLykipaAGKTGTTQNWADAWAVGFT 683
Cdd:PRK09506 648 -----YQSFPQAERAVPAQAAYLTLYTMQQVVQRGT-------GRQLGAKYPNLHL-----AGKTGTTNDLVDSWFAGID 710
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 684 PYYTSVFWFGFDKPGQSlglQLTGSTlsgYAWADYMKKIHNGLPMKDFSKPATGVIEATV 743
Cdd:PRK09506 711 GKEVTITWVGRDNNQPT---KLYGAS---GAMTIYQRYLENQTPTPLNLTPPEDIVDMGV 764
|
|
| PRK11240 |
PRK11240 |
penicillin-binding protein 1C; Provisional |
82-770 |
4.29e-42 |
|
penicillin-binding protein 1C; Provisional
Pssm-ID: 183049 [Multi-domain] Cd Length: 772 Bit Score: 165.26 E-value: 4.29e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 82 LDALITREDRLFYSHHGYSVKALFRAVFGKLT-GMSLGGGSTLTQQIAGTLfcDRTDMSIRRKLKELWWAIQMERRYTKD 160
Cdd:PRK11240 75 LEALINYEDRWFWKHPGVNPFSVARAAWQDLTsGRVISGGSTLTMQVARLL--DPHPRTFGGKIRQLWRALQLEWHLSKR 152
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 161 EILELYLNKIYFGGGTYGVSAASKYYFGHDATEITPAEAAILVIQLSNPAFYNPFEYPNRAMDRQKDVLSTMVSAGYISK 240
Cdd:PRK11240 153 EILTLYLNRAPFGGTLQGIGAASWAYLGKSPANLSYAEAALLAVLPQAPSRLRPDRWPERAEAARNKVLERMAEQGVWSA 232
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 241 EQADESFDD-YWanfdytrtatAAVFNHDDNAPWFSeyvRRELGNliygtediySSGFTVNTTLNLKNQAVAQDVMdryi 319
Cdd:PRK11240 233 EQVKESREEpVW----------LAPRQMPQLAPLFA---RMMLGK---------SKSDKIVTTLDAGLQRRLEDLA---- 286
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 320 ryANRTYQRStgERTNQAFSVytpmtellaltfnlnslkvseqrneaiskatytsqinpvmdvmslmfgVDslklgivnk 399
Cdd:PRK11240 287 --LNWKGRLP--PRSSLAMIV------------------------------------------------VD--------- 305
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 400 aNQQAKVKvskttiegtmialendtGYITSLvggsKFDSENQF--IRAVQAKLQPGSAFKPLYYSAAIDSRKFTPTSIIS 477
Cdd:PRK11240 306 -HTDMAVR-----------------GWVGSV----DLNDDSRFghVDMVNAIRSPGSVLKPFVYGLALDDGLIHPASLLQ 363
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 478 DTPVvfHTADgkpYIPQNFRGEWKGDVELWYALAHSMNVPSLKVLDGIG---FEAGInRSIAL-LGIPKeevpyrGFVPG 553
Cdd:PRK11240 364 DVPR--RTGD---YRPGNFDSGFHGPVSMSEALVRSLNLPAVQVLEAYGpkrFAAKL-RNVGLpLYLPA------GAEPN 431
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 554 YPIGLGVCSVRPVELARAYSVFASGGKEvtpiairsvedknGNVILNPEKELRTalqakgaaAQVISPQTAFVMTELLQN 633
Cdd:PRK11240 432 LSLILGGAGARLEDMVAAYSAFARHGKA-------------AKLRLQPDDPLLE--------RPLMSPGAAWIIRRIMAD 490
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 634 TVRSgtlagpssngdklrykDSNGHLYKI-PAAGKTGTTQNWADAWAVGFTPYYTSVFWFGfdKP-GQSLGLQLtgstls 711
Cdd:PRK11240 491 EAQP----------------LPDAALPRVvPLAWKTGTSYGYRDAWAIGVNARYVIGIWTG--RPdGTPVVGQF------ 546
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2540503203 712 GYAWA-DYMKKIHN-----------GLPMKdfSKPATgVIEATVCSVSGGILT---PECgDHKVTAWYLEGTQP 770
Cdd:PRK11240 547 GFASAvPLLNQVNNlllsrssqrgaNLPED--PRPAS-VSRGVICWPGGQSLPegdSNC-RRRLATWLLDGSQP 616
|
|
| PRK13481 |
PRK13481 |
glycosyltransferase; Provisional |
66-246 |
9.51e-37 |
|
glycosyltransferase; Provisional
Pssm-ID: 184078 [Multi-domain] Cd Length: 232 Bit Score: 138.40 E-value: 9.51e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 66 EEKREIISIRDLPQCMLDALITREDRLFYSHHGYSVKALFRAVFGKLTGMSLGGGSTLTQQIAGTLFCDrTDMSIRRKLK 145
Cdd:PRK13481 42 ENKSSFVSADNMPEYVKGAFISMEDERFYKHHGFDLKGTTRALFSTISDRDVQGGSTITQQVVKNYFYD-NERSFTRKVK 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 146 ELWWAIQMERRYTKDEILELYLNKIYFGGGTYGVSAASKYYFG-------HDATEITPAEAAILVIQLSNPAFYNPFEYP 218
Cdd:PRK13481 121 ELFVAHRVEKQYSKNEILSFYLNNIYFGDNQYTLEGAANHYFGttvnknsTTMSHITVLQSAILASKVNAPSVYNINDMS 200
|
170 180
....*....|....*....|....*...
gi 2540503203 219 NRAMDRQKDVLSTMVSAGYISKEQADES 246
Cdd:PRK13481 201 ENFTQRVSTNLEKMKQQNYINETQYQQA 228
|
|
| mono_pep_trsgly |
TIGR02070 |
monofunctional biosynthetic peptidoglycan transglycosylase; This family is one of the ... |
84-236 |
1.03e-28 |
|
monofunctional biosynthetic peptidoglycan transglycosylase; This family is one of the transglycosylases involved in the late stages of peptidoglycan biosynthesis. Members tend to be small, about 240 amino acids in length, and consist almost entirely of a domain described by pfam00912 for transglycosylases. Species with this protein will have several other transglycosylases as well. All species with this protein are Proteobacteria that produce murein (peptidoglycan). [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273951 [Multi-domain] Cd Length: 224 Bit Score: 114.87 E-value: 1.03e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 84 ALITREDRLFYSHHGYSVKALFRAV-FGKLTGMSLGGGSTLTQQIAGTLFCdRTDMSIRRKLKELWWAIQMERRYTKDEI 162
Cdd:TIGR02070 70 AVIASEDAKFVEHHGFDWEAIQDALeKNEKSGKVVRGGSTISQQLAKNLFL-WSGRSYLRKGLEAWATWMLETWWSKQRI 148
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2540503203 163 LELYLNKIYFGGGTYGVSAASKYYFGHDATEITPAEAAILVIQLSNPAFYNPFEYPNRAMDRQKDVLSTMVSAG 236
Cdd:TIGR02070 149 LEVYLNSVEWGNGVFGAEAAARYYFKRSASNLTRGQAARLAAVLPNPKYYDENRPGPYVRRKATWILKQMGYLG 222
|
|
| FtsI |
COG0768 |
Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell ... |
415-685 |
2.48e-25 |
|
Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell cycle control, cell division, chromosome partitioning, Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440531 [Multi-domain] Cd Length: 568 Bit Score: 111.45 E-value: 2.48e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 415 GTMIALENDTGYITSLVGGSKFDSeNQFI---------RAVQAKLQPGSAFKPLYYSAAIDSRKFTPTSIISDT------ 479
Cdd:COG0768 249 GAVVVMDPKTGEILAMASYPSFDP-NLFVggpdeplrnRAVQGTYEPGSTFKPFTAAAALEEGVITPDTTFDCPgyyrvg 327
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 480 PVVFHTADGKPYIPQNFRGewkgdvelwyALAHSMNVPSLKVLDGIGFEAgINRSIALLG--------IPKEEvpyRGFV 551
Cdd:COG0768 328 GRTIRDWDRGGHGTLTLTE----------ALAKSSNVGFYKLALRLGIDK-LYDYLKKFGlgqktgidLPGEA---SGLL 393
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 552 PGY-----------PIGLGVcSVRPVELARAYSVFASGGKEVTPIAIRSVEDKNGNVILNPEKELRtalqakgaaaQVIS 620
Cdd:COG0768 394 PSPkrwypgetatmSIGQGL-SVTPLQLAQAYAAIANGGVLVKPHLVKEIVDPDGEVVKEEPEVLR----------RVIS 462
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 621 PQTAFVMTELLQNTVRS--GTlagpssngdklrykdsnGHLYKIP---AAGKTGTTQNWAD-----------AWAVGFTP 684
Cdd:COG0768 463 PETAETVREGMEGVVNEpgGT-----------------ARRAAIPgyrVAGKTGTAQVVDIgnggyykgrhiASFVGFAP 525
|
.
gi 2540503203 685 Y 685
Cdd:COG0768 526 A 526
|
|
| Transpeptidase |
pfam00905 |
Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss: ... |
415-685 |
1.76e-21 |
|
Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss:P14677) is conserved in all members of this family.
Pssm-ID: 425939 [Multi-domain] Cd Length: 296 Bit Score: 95.95 E-value: 1.76e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 415 GTMIALENDTGYITSLVGGSKFDSENQF----IRAVQAKLQPGSAFKPLYYSAAIDSRKFTPTSIISDTPvvFHTADGKP 490
Cdd:pfam00905 1 GSAVVLDPKTGEVLAMVGKPSYDPNGFIgplrNRAVTSRYEPGSTFKPFTALAALDNGVLKPDETIFDWP--GKQQGGKS 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 491 YIPQNFRGEWKGDVELWyaLAHSMNVPSLKV------------LDGIGFEA--GINRSIALLGIPKEEVpYRGFVPGYPI 556
Cdd:pfam00905 79 IGDWNQDQVGIGTLRQA--LEYSSNWYMQKLaqklgadklrsyLKKFGYGNktGIGLPGENAGYLTPYW-LEGATASFGI 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 557 GLgvcSVRPVELARAYSVFASGGKEVTPIAIRSVEDKNGNVILNpekelrtalqakgaaAQVISPQTAFVMTELLQNTVR 636
Cdd:pfam00905 156 GL---TITPLQQAQAYAAIANGGKLVPPHLVKSIEDKVDPKVLN---------------KLPISKSTAEKVKDMLRLVVN 217
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 637 SGTLAGPssngdklrykdSNGHLYKIpaAGKTGTTQ-----------NWADAWAVGFTPY 685
Cdd:pfam00905 218 DGTGTGT-----------AAVPGYKV--AGKTGTAQvagpkgggyydGAQIGWFVGYAPA 264
|
|
| pbp2_mrdA |
TIGR03423 |
penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 ... |
415-685 |
8.40e-18 |
|
penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 (PBP-2), a protein whose gene (designated pbpA or mrdA) generally is found next to the gene for RodA, a protein required for rod (bacillus) shape in many bacteria. PBP-2 acts as a transpeptidase for cell elongation (hence, rod-shape). [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 274573 [Multi-domain] Cd Length: 592 Bit Score: 87.96 E-value: 8.40e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 415 GTMIALENDTGYITSLVggSK--FDSeNQFI---------------------RAVQAKLQPGSAFKPLYYSAAIDSRKFT 471
Cdd:TIGR03423 249 GAVVVMDPRTGEILAMV--STpsFDP-NLFVdgisskdykallndpdrpllnRAIQGVYPPGSTFKPVVALAALEEGVIT 325
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 472 PTSIISDTpvvfhtadGKPYIPQNFRGEWK----GDVELWYALAHSMNVpslkVLDGIGFEAGINRsIA----------L 537
Cdd:TIGR03423 326 PETRIYCP--------GYFQLGGRRFRCWKrgghGRVDLRKAIEESCDV----YFYQLALRLGIDK-IAeyakrfgfgqK 392
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 538 LGIP-KEEVPyrGFVP---------GYP----------IGLGVCSVRPVELARAYSVFASGGKEVTPIAIRSVEDKNGNV 597
Cdd:TIGR03423 393 TGIDlPGEKS--GLVPsrewkrkrfGQPwypgdtlnvsIGQGYVLVTPLQLAVATAALANGGKLYKPHLVKSIEDPDGGV 470
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2540503203 598 ILNPEKELRTALQakgaaaqvISPQTAFVMTELLQNTVRS--GTlagpssnGDKLRYKDSnghlykIPAAGKTGTTQ--- 672
Cdd:TIGR03423 471 VRRTEPEVLRPLP--------ISPENLDVVREGMRDVVNGpgGT-------ARRARLGLP------YKMAGKTGTAQvvs 529
|
330 340
....*....|....*....|....*...
gi 2540503203 673 --------------NWAD-AWAVGFTPY 685
Cdd:TIGR03423 530 lkqgekydaeqipeRLRDhALFVAFAPY 557
|
|
| |
