View
Concise Results
Standard Results
Full Results
phosphopyruvate hydratase [Nitrosarchaeum sp.]
Protein Classification
phosphopyruvate hydratase family protein ( domain architecture ID 1000610 )
phosphopyruvate hydratase family protein similar to phosphopyruvate hydratase that catalyzes the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways
List of domain hits
Name
Accession
Description
Interval
E-value
eno super family
cl35058 enolase; Provisional
1-402
1.81e-124
enolase; Provisional
PRK00077 :Pssm-ID: 234617 [Multi-domain]
Cd Length: 425
Bit Score: 366.72
E-value: 1.81e-124
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541357225 1 MSKI TS I NG R I I YN SRG SK T I EV DIIS E NKFL GR VCA PSGAS V G KY EAV SFPNEKPE esl R M L N K N ------------ A Q 68
Cdd:PRK00077 1 MSKI ED I IA R E I LD SRG NP T V EV EVTL E DGAF GR AAV PSGAS T G ER EAV ELRDGDKS --- R Y L G K G vlkavenvneei A P 77
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541357225 69 KF IGL ESS D LKTVHDTLRSI D QSS N YA K I G GALAFA VS I A SMES A SKANDTS L FQT L SSESSFKF P F P LG NI LG GGAHA G 148
Cdd:PRK00077 78 AL IGL DAL D QRAIDKAMIEL D GTP N KS K L G ANAILG VS L A VAKA A ADSLGLP L YRY L GGPNAKVL P V P MM NI IN GGAHA D 157
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541357225 149 PGT p DIQE IL I CAI G TKTIRD A IETNLA V HKE L RRI L EKED ps FTNGR GDEGG W AP K LK - NE K AL E L SAK A C E NL G FTL G 227
Cdd:PRK00077 158 NNV - DIQE FM I MPV G APSFKE A LRMGAE V FHT L KKV L KEKG -- LSTAV GDEGG F AP N LK s NE E AL D L ILE A I E KA G YKP G 234
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541357225 228 KEV AL GV D F A S S TQW se EKE KYV Y E RA G F vn S SEE Q I EFA A NIIK KY KLIYA ED AVH E EAF E DMAE LT T K F - P K TLVT GD 306
Cdd:PRK00077 235 EDI AL AL D C A A S EFY -- KDG KYV L E GE G L -- T SEE M I DYL A ELVD KY PIVSI ED GLD E NDW E GWKL LT E K L g D K VQLV GD 310
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541357225 307 DL T VTN KDV L T K A I NMKSC N AAIL KVNQ A G S L YDAFEFAKV A NQNNIKLIT SHRSGE ST D SH IA HIGL AT KSKML K V G IV 386
Cdd:PRK00077 311 DL F VTN TKR L K K G I EKGAA N SILI KVNQ I G T L TETLDAIEL A KRAGYTAVV SHRSGE TE D TT IA DLAV AT NAGQI K T G SL 390
410
....*....|....*..
gi 2541357225 387 G - G ER V AK L N E L I R LS E 402
Cdd:PRK00077 391 S r S ER I AK Y N Q L L R IE E 407
Name
Accession
Description
Interval
E-value
eno
PRK00077 enolase; Provisional
1-402
1.81e-124
enolase; Provisional
Pssm-ID: 234617 [Multi-domain]
Cd Length: 425
Bit Score: 366.72
E-value: 1.81e-124
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541357225 1 MSKI TS I NG R I I YN SRG SK T I EV DIIS E NKFL GR VCA PSGAS V G KY EAV SFPNEKPE esl R M L N K N ------------ A Q 68
Cdd:PRK00077 1 MSKI ED I IA R E I LD SRG NP T V EV EVTL E DGAF GR AAV PSGAS T G ER EAV ELRDGDKS --- R Y L G K G vlkavenvneei A P 77
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541357225 69 KF IGL ESS D LKTVHDTLRSI D QSS N YA K I G GALAFA VS I A SMES A SKANDTS L FQT L SSESSFKF P F P LG NI LG GGAHA G 148
Cdd:PRK00077 78 AL IGL DAL D QRAIDKAMIEL D GTP N KS K L G ANAILG VS L A VAKA A ADSLGLP L YRY L GGPNAKVL P V P MM NI IN GGAHA D 157
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541357225 149 PGT p DIQE IL I CAI G TKTIRD A IETNLA V HKE L RRI L EKED ps FTNGR GDEGG W AP K LK - NE K AL E L SAK A C E NL G FTL G 227
Cdd:PRK00077 158 NNV - DIQE FM I MPV G APSFKE A LRMGAE V FHT L KKV L KEKG -- LSTAV GDEGG F AP N LK s NE E AL D L ILE A I E KA G YKP G 234
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541357225 228 KEV AL GV D F A S S TQW se EKE KYV Y E RA G F vn S SEE Q I EFA A NIIK KY KLIYA ED AVH E EAF E DMAE LT T K F - P K TLVT GD 306
Cdd:PRK00077 235 EDI AL AL D C A A S EFY -- KDG KYV L E GE G L -- T SEE M I DYL A ELVD KY PIVSI ED GLD E NDW E GWKL LT E K L g D K VQLV GD 310
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541357225 307 DL T VTN KDV L T K A I NMKSC N AAIL KVNQ A G S L YDAFEFAKV A NQNNIKLIT SHRSGE ST D SH IA HIGL AT KSKML K V G IV 386
Cdd:PRK00077 311 DL F VTN TKR L K K G I EKGAA N SILI KVNQ I G T L TETLDAIEL A KRAGYTAVV SHRSGE TE D TT IA DLAV AT NAGQI K T G SL 390
410
....*....|....*..
gi 2541357225 387 G - G ER V AK L N E L I R LS E 402
Cdd:PRK00077 391 S r S ER I AK Y N Q L L R IE E 407
enolase
cd03313 Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of ...
6-402
1.99e-123
Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions.
Pssm-ID: 239429 [Multi-domain]
Cd Length: 408
Bit Score: 363.34
E-value: 1.99e-123
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541357225 6 S I NG R I I YN SRG SK T I EV DIIS E NKFL GR VCA PSGAS V G KY EAV SFPNEKPE esl R M L N K N ------------ A QKF IG L 73
Cdd:cd03313 1 K I KA R E I LD SRG NP T V EV EVTT E DGGV GR AAV PSGAS T G EH EAV ELRDGDKS --- R Y L G K G vlkavknvneii A PAL IG M 77
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541357225 74 ESS D LKTVHDT L RSI D QSS N YA K I G GALAFA VS I A SMES A SK A NDTS L FQT L SSESSFKF P F P LG N ILG GGAHAG p GTP D 153
Cdd:cd03313 78 DVT D QRAIDKL L IEL D GTP N KS K L G ANAILG VS L A VAKA A AA A LGLP L YRY L GGLAAYVL P V P MF N VIN GGAHAG - NKL D 156
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541357225 154 I QE IL I CAI G TKTIRD A IETNLA V HKE L RRI L E K EDPSFTNGR GDEGG W AP K L K - NE K AL E L SAK A C E NL G FTL GK EV A L 232
Cdd:cd03313 157 F QE FM I VPV G APSFSE A LRMGAE V YHT L KKV L K K KGGLLATNV GDEGG F AP N L S s NE E AL D L LVE A I E KA G YEP GK KI A I 236
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541357225 233 GV D F A S S TQWS E E K EK Y VYERAGFV n S SEE Q I EFAANII KKY KLIYA ED AVH E EAF E DM A E LT T K F - P K TLVT GDDL T VT 311
Cdd:cd03313 237 AL D V A A S EFYD E G K YV Y DSDEGKKL - T SEE L I DYYKELV KKY PIVSI ED PFD E DDW E GW A K LT A K L g D K IQIV GDDL F VT 315
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541357225 312 N KDV L T K A I NM K SC NA AIL KVNQ A G S L YDAF E FA K V A NQ N NIKLIT SHRSGE ST D SH IA HIGL A TKSKML K V G I - VGG ER 390
Cdd:cd03313 316 N PER L K K G I EK K AA NA LLI KVNQ I G T L TETI E AI K L A KK N GYGVVV SHRSGE TE D TF IA DLAV A LGAGQI K T G A p CRS ER 395
410
....*....|..
gi 2541357225 391 V AK L N E L I R LS E 402
Cdd:cd03313 396 T AK Y N Q L L R IE E 407
eno
TIGR01060 phosphopyruvate hydratase; Alternate name: enolase [Energy metabolism, Glycolysis ...
4-402
1.61e-113
phosphopyruvate hydratase; Alternate name: enolase [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 213580 [Multi-domain]
Cd Length: 425
Bit Score: 338.56
E-value: 1.61e-113
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541357225 4 I TS I NG R I I YN SRG SK T I EV DI I S E NKFL GR VCA PSGAS V G KY EA VSFPNEKPE esl R M L N K N ------------ A QKF I 71
Cdd:TIGR01060 1 I VD I RA R E I LD SRG NP T V EV EV I L E DGTF GR AAV PSGAS T G ER EA LELRDGDKK --- R Y L G K G vlkavenvneii A PEL I 77
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541357225 72 G LESS D LKTVHDT L RSI D QSS N YA K I G GALAFA VS I A SMES A SKANDTS L FQT L SSESSFKF P F P LG NI LG GGAHA GPG t 151
Cdd:TIGR01060 78 G MDAT D QREIDQI L IEL D GTP N KS K L G ANAILG VS M A VAKA A ADSLGLP L YRY L GGFNAYVL P V P MM NI IN GGAHA DNN - 156
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541357225 152 P D I QE IL I CAI G TKTI R D A IETNLA V HKE L RRI L EKED ps FTN G R GDEGG W AP K L K - NE K ALE LSAK A C E NL G FTL G KE V 230
Cdd:TIGR01060 157 L D F QE FM I MPV G APSF R E A LRMGAE V FHA L KKL L KEKG -- LAT G V GDEGG F AP N L A s NE E ALE IIVE A I E KA G YKP G ED V 234
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541357225 231 AL GV D F A S S TQWS EE KE KYVY ERAGFVNS SEE Q IE FAANIIK KY KL I YA ED AVH EE AF E DM AELT TKF - P K TLVT GDDL T 309
Cdd:TIGR01060 235 AL AL D C A A S EFYD EE DG KYVY KGENKQLT SEE M IE YYEELVE KY PI I SI ED GLS EE DW E GW AELT KRL g D K VQIV GDDL F 314
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541357225 310 VTN KDV L TKA I N M KSC N AAIL K V NQ A G S L YDAFEFAKV A NQNNIKLIT SHRSGE ST D SH IA HIGL AT KSKML K V G IVG - G 388
Cdd:TIGR01060 315 VTN TEI L REG I E M GVA N SILI K P NQ I G T L TETLDAIEL A KKAGYTAVI SHRSGE TE D TT IA DLAV AT NAGQI K T G SLS r S 394
410
....*....|....
gi 2541357225 389 ER V AK L N E L I R LS E 402
Cdd:TIGR01060 395 ER I AK Y N Q L L R IE E 408
Eno
COG0148 Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: ...
1-402
4.21e-102
Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 439918 [Multi-domain]
Cd Length: 426
Bit Score: 309.64
E-value: 4.21e-102
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541357225 1 MS K I TSING R I I YN SRG SK T I EV DIIS E NKFL GR VCA PSGAS V G KY EAV sfpnekpe E s LR MLN K N -------------- 66
Cdd:COG0148 1 MS R I EDVHA R E I LD SRG NP T V EV EVTL E DGAV GR AAV PSGAS T G SH EAV -------- E - LR DGD K S rylgkgvlkavenv 71
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541357225 67 ---- A QKF IG LESS D LKTVHDTLRSI D QSS N YAKI G GALAFA VS I A SMES A SK A NDTS L FQT L SSESSFKF P F P LG NI LG 142
Cdd:COG0148 72 neei A PAL IG MDAT D QRAIDRAMIEL D GTP N KSRL G ANAILG VS L A VAKA A AA A LGLP L YRY L GGVNAKTL P V P MM NI IN 151
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541357225 143 GGAHA GPGT p DIQE IL I CAI G TKTIRD A IETNLA V HKE L RRI L EKE dp SFTNGR GDEGG W AP K LK - NE K ALEL SAK A C E N 221
Cdd:COG0148 152 GGAHA DNNV - DIQE FM I MPV G APSFSE A LRMGAE V FHA L KKV L KEK -- GLSTAV GDEGG F AP N LK s NE E ALEL ILE A I E K 228
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541357225 222 L G FTL G KEV AL GV D F A S S tqws E -- EKE KY VYERA G FVNS SEE Q I EFA A NIIK KY KLIYA ED AVH E EAFEDMAE LT T K FP 299
Cdd:COG0148 229 A G YKP G EDI AL AL D V A A S ---- E fy KDG KY HLKGE G KELT SEE M I DYY A DLVD KY PIVSI ED GLA E DDWDGWKL LT E K LG 304
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541357225 300 KT -- LV t GDDL T VTN KDV L T K A I NMKSC N AAIL KVNQ A G S L YDAFEFAKV A NQNNIKLIT SHRSGE ST D SH IA HIGL AT K 377
Cdd:COG0148 305 DK vq LV - GDDL F VTN PKR L K K G I EEGAA N SILI KVNQ I G T L TETLDAIEL A KRAGYTAVI SHRSGE TE D TT IA DLAV AT N 383
410 420
....*....|....*....|....*.
gi 2541357225 378 SKML K V G - IVGG ERVAK L N E L I R LS E 402
Cdd:COG0148 384 AGQI K T G s PSRS ERVAK Y N Q L L R IE E 409
Enolase_C
pfam00113 Enolase, C-terminal TIM barrel domain;
130-402
5.37e-54
Enolase, C-terminal TIM barrel domain;
Pssm-ID: 395063
Cd Length: 296
Bit Score: 181.14
E-value: 5.37e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541357225 130 S FKF P F P LG N ILG GG A HAG p GTPDI QE IL I CAI G TKTIRD A IETNLA V HKE L RRI L EKEDPSFTNGR GDEGG W AP K L K - N 208
Cdd:pfam00113 1 S YVL P V P MM N VIN GG S HAG - NNLAF QE FM I LPT G APSFSE A MRMGAE V YHH L KSV L KAKYGQSATNV GDEGG F AP N L Q s N 79
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541357225 209 EK AL E L SAK A C E NL G FTL gk EVALGV D F ASS TQWSEEKE KY VYERA G FVN ------ S S EEQIEFAANII KKY KLIYA ED A 282
Cdd:pfam00113 80 KE AL D L IVE A I E KA G YKG -- KIKIAM D V ASS EFYNKKDG KY DLDFK G EKS dkskkl T S AQLADLYEELV KKY PIVSI ED P 157
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541357225 283 VH E EAF E DMAE LT TKF - P K TLVT GDDLTVTN KDV L TK AI NM K SC NA AI LKVNQ A GSL YDAFEFA K V A NQNNIKLIT SHRS 361
Cdd:pfam00113 158 FD E DDW E AWKY LT ERL g D K VQIV GDDLTVTN PKR L KT AI EK K IA NA LL LKVNQ I GSL TESIAAV K M A KDAGWGVMV SHRS 237
250 260 270 280
....*....|....*....|....*....|....*....|..
gi 2541357225 362 GE ST D SH IA HIGLATKSKML K V G IVG - G ER V AK L N E L I R LS E 402
Cdd:pfam00113 238 GE TE D TT IA DLAVGLNAGQI K T G APC r S ER L AK Y N Q L L R IE E 279
Name
Accession
Description
Interval
E-value
eno
PRK00077 enolase; Provisional
1-402
1.81e-124
enolase; Provisional
Pssm-ID: 234617 [Multi-domain]
Cd Length: 425
Bit Score: 366.72
E-value: 1.81e-124
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541357225 1 MSKI TS I NG R I I YN SRG SK T I EV DIIS E NKFL GR VCA PSGAS V G KY EAV SFPNEKPE esl R M L N K N ------------ A Q 68
Cdd:PRK00077 1 MSKI ED I IA R E I LD SRG NP T V EV EVTL E DGAF GR AAV PSGAS T G ER EAV ELRDGDKS --- R Y L G K G vlkavenvneei A P 77
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541357225 69 KF IGL ESS D LKTVHDTLRSI D QSS N YA K I G GALAFA VS I A SMES A SKANDTS L FQT L SSESSFKF P F P LG NI LG GGAHA G 148
Cdd:PRK00077 78 AL IGL DAL D QRAIDKAMIEL D GTP N KS K L G ANAILG VS L A VAKA A ADSLGLP L YRY L GGPNAKVL P V P MM NI IN GGAHA D 157
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541357225 149 PGT p DIQE IL I CAI G TKTIRD A IETNLA V HKE L RRI L EKED ps FTNGR GDEGG W AP K LK - NE K AL E L SAK A C E NL G FTL G 227
Cdd:PRK00077 158 NNV - DIQE FM I MPV G APSFKE A LRMGAE V FHT L KKV L KEKG -- LSTAV GDEGG F AP N LK s NE E AL D L ILE A I E KA G YKP G 234
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541357225 228 KEV AL GV D F A S S TQW se EKE KYV Y E RA G F vn S SEE Q I EFA A NIIK KY KLIYA ED AVH E EAF E DMAE LT T K F - P K TLVT GD 306
Cdd:PRK00077 235 EDI AL AL D C A A S EFY -- KDG KYV L E GE G L -- T SEE M I DYL A ELVD KY PIVSI ED GLD E NDW E GWKL LT E K L g D K VQLV GD 310
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541357225 307 DL T VTN KDV L T K A I NMKSC N AAIL KVNQ A G S L YDAFEFAKV A NQNNIKLIT SHRSGE ST D SH IA HIGL AT KSKML K V G IV 386
Cdd:PRK00077 311 DL F VTN TKR L K K G I EKGAA N SILI KVNQ I G T L TETLDAIEL A KRAGYTAVV SHRSGE TE D TT IA DLAV AT NAGQI K T G SL 390
410
....*....|....*..
gi 2541357225 387 G - G ER V AK L N E L I R LS E 402
Cdd:PRK00077 391 S r S ER I AK Y N Q L L R IE E 407
enolase
cd03313 Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of ...
6-402
1.99e-123
Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions.
Pssm-ID: 239429 [Multi-domain]
Cd Length: 408
Bit Score: 363.34
E-value: 1.99e-123
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541357225 6 S I NG R I I YN SRG SK T I EV DIIS E NKFL GR VCA PSGAS V G KY EAV SFPNEKPE esl R M L N K N ------------ A QKF IG L 73
Cdd:cd03313 1 K I KA R E I LD SRG NP T V EV EVTT E DGGV GR AAV PSGAS T G EH EAV ELRDGDKS --- R Y L G K G vlkavknvneii A PAL IG M 77
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541357225 74 ESS D LKTVHDT L RSI D QSS N YA K I G GALAFA VS I A SMES A SK A NDTS L FQT L SSESSFKF P F P LG N ILG GGAHAG p GTP D 153
Cdd:cd03313 78 DVT D QRAIDKL L IEL D GTP N KS K L G ANAILG VS L A VAKA A AA A LGLP L YRY L GGLAAYVL P V P MF N VIN GGAHAG - NKL D 156
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541357225 154 I QE IL I CAI G TKTIRD A IETNLA V HKE L RRI L E K EDPSFTNGR GDEGG W AP K L K - NE K AL E L SAK A C E NL G FTL GK EV A L 232
Cdd:cd03313 157 F QE FM I VPV G APSFSE A LRMGAE V YHT L KKV L K K KGGLLATNV GDEGG F AP N L S s NE E AL D L LVE A I E KA G YEP GK KI A I 236
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541357225 233 GV D F A S S TQWS E E K EK Y VYERAGFV n S SEE Q I EFAANII KKY KLIYA ED AVH E EAF E DM A E LT T K F - P K TLVT GDDL T VT 311
Cdd:cd03313 237 AL D V A A S EFYD E G K YV Y DSDEGKKL - T SEE L I DYYKELV KKY PIVSI ED PFD E DDW E GW A K LT A K L g D K IQIV GDDL F VT 315
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541357225 312 N KDV L T K A I NM K SC NA AIL KVNQ A G S L YDAF E FA K V A NQ N NIKLIT SHRSGE ST D SH IA HIGL A TKSKML K V G I - VGG ER 390
Cdd:cd03313 316 N PER L K K G I EK K AA NA LLI KVNQ I G T L TETI E AI K L A KK N GYGVVV SHRSGE TE D TF IA DLAV A LGAGQI K T G A p CRS ER 395
410
....*....|..
gi 2541357225 391 V AK L N E L I R LS E 402
Cdd:cd03313 396 T AK Y N Q L L R IE E 407
eno
TIGR01060 phosphopyruvate hydratase; Alternate name: enolase [Energy metabolism, Glycolysis ...
4-402
1.61e-113
phosphopyruvate hydratase; Alternate name: enolase [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 213580 [Multi-domain]
Cd Length: 425
Bit Score: 338.56
E-value: 1.61e-113
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541357225 4 I TS I NG R I I YN SRG SK T I EV DI I S E NKFL GR VCA PSGAS V G KY EA VSFPNEKPE esl R M L N K N ------------ A QKF I 71
Cdd:TIGR01060 1 I VD I RA R E I LD SRG NP T V EV EV I L E DGTF GR AAV PSGAS T G ER EA LELRDGDKK --- R Y L G K G vlkavenvneii A PEL I 77
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541357225 72 G LESS D LKTVHDT L RSI D QSS N YA K I G GALAFA VS I A SMES A SKANDTS L FQT L SSESSFKF P F P LG NI LG GGAHA GPG t 151
Cdd:TIGR01060 78 G MDAT D QREIDQI L IEL D GTP N KS K L G ANAILG VS M A VAKA A ADSLGLP L YRY L GGFNAYVL P V P MM NI IN GGAHA DNN - 156
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541357225 152 P D I QE IL I CAI G TKTI R D A IETNLA V HKE L RRI L EKED ps FTN G R GDEGG W AP K L K - NE K ALE LSAK A C E NL G FTL G KE V 230
Cdd:TIGR01060 157 L D F QE FM I MPV G APSF R E A LRMGAE V FHA L KKL L KEKG -- LAT G V GDEGG F AP N L A s NE E ALE IIVE A I E KA G YKP G ED V 234
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541357225 231 AL GV D F A S S TQWS EE KE KYVY ERAGFVNS SEE Q IE FAANIIK KY KL I YA ED AVH EE AF E DM AELT TKF - P K TLVT GDDL T 309
Cdd:TIGR01060 235 AL AL D C A A S EFYD EE DG KYVY KGENKQLT SEE M IE YYEELVE KY PI I SI ED GLS EE DW E GW AELT KRL g D K VQIV GDDL F 314
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541357225 310 VTN KDV L TKA I N M KSC N AAIL K V NQ A G S L YDAFEFAKV A NQNNIKLIT SHRSGE ST D SH IA HIGL AT KSKML K V G IVG - G 388
Cdd:TIGR01060 315 VTN TEI L REG I E M GVA N SILI K P NQ I G T L TETLDAIEL A KKAGYTAVI SHRSGE TE D TT IA DLAV AT NAGQI K T G SLS r S 394
410
....*....|....
gi 2541357225 389 ER V AK L N E L I R LS E 402
Cdd:TIGR01060 395 ER I AK Y N Q L L R IE E 408
Eno
COG0148 Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: ...
1-402
4.21e-102
Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 439918 [Multi-domain]
Cd Length: 426
Bit Score: 309.64
E-value: 4.21e-102
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541357225 1 MS K I TSING R I I YN SRG SK T I EV DIIS E NKFL GR VCA PSGAS V G KY EAV sfpnekpe E s LR MLN K N -------------- 66
Cdd:COG0148 1 MS R I EDVHA R E I LD SRG NP T V EV EVTL E DGAV GR AAV PSGAS T G SH EAV -------- E - LR DGD K S rylgkgvlkavenv 71
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541357225 67 ---- A QKF IG LESS D LKTVHDTLRSI D QSS N YAKI G GALAFA VS I A SMES A SK A NDTS L FQT L SSESSFKF P F P LG NI LG 142
Cdd:COG0148 72 neei A PAL IG MDAT D QRAIDRAMIEL D GTP N KSRL G ANAILG VS L A VAKA A AA A LGLP L YRY L GGVNAKTL P V P MM NI IN 151
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541357225 143 GGAHA GPGT p DIQE IL I CAI G TKTIRD A IETNLA V HKE L RRI L EKE dp SFTNGR GDEGG W AP K LK - NE K ALEL SAK A C E N 221
Cdd:COG0148 152 GGAHA DNNV - DIQE FM I MPV G APSFSE A LRMGAE V FHA L KKV L KEK -- GLSTAV GDEGG F AP N LK s NE E ALEL ILE A I E K 228
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541357225 222 L G FTL G KEV AL GV D F A S S tqws E -- EKE KY VYERA G FVNS SEE Q I EFA A NIIK KY KLIYA ED AVH E EAFEDMAE LT T K FP 299
Cdd:COG0148 229 A G YKP G EDI AL AL D V A A S ---- E fy KDG KY HLKGE G KELT SEE M I DYY A DLVD KY PIVSI ED GLA E DDWDGWKL LT E K LG 304
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541357225 300 KT -- LV t GDDL T VTN KDV L T K A I NMKSC N AAIL KVNQ A G S L YDAFEFAKV A NQNNIKLIT SHRSGE ST D SH IA HIGL AT K 377
Cdd:COG0148 305 DK vq LV - GDDL F VTN PKR L K K G I EEGAA N SILI KVNQ I G T L TETLDAIEL A KRAGYTAVI SHRSGE TE D TT IA DLAV AT N 383
410 420
....*....|....*....|....*.
gi 2541357225 378 SKML K V G - IVGG ERVAK L N E L I R LS E 402
Cdd:COG0148 384 AGQI K T G s PSRS ERVAK Y N Q L L R IE E 409
PTZ00081
PTZ00081 enolase; Provisional
1-402
6.33e-74
enolase; Provisional
Pssm-ID: 240259 [Multi-domain]
Cd Length: 439
Bit Score: 237.25
E-value: 6.33e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541357225 1 MS K I T SI NG R I I YN SRG SK T I EVD IIS E NKFL g R VCA PSGAS V G K YEA VSFPNEKPE esl R M L N K NAQ K ----------- 69
Cdd:PTZ00081 1 MS T I K SI KA R E I LD SRG NP T V EVD LTT E KGVF - R AAV PSGAS T G I YEA LELRDGDKS --- R Y L G K GVL K avenvneiiap 76
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541357225 70 - F IG LESS D L K TVHDTL - RSI D QSS N Y ----- A K I G GALAF AVS I A SMES A SK A NDTS L FQT L S ----- SESS F KF P F P L 137
Cdd:PTZ00081 77 a L IG KDVT D Q K KLDKLM v EQL D GTK N E wgwck S K L G ANAIL AVS M A VARA A AA A KGVP L YKY L A qlagk PTDK F VL P V P C 156
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541357225 138 G N ILG GG A HAG PGTP d I QE IL I CAI G TKTIRD A IETNLA V HKE L RRILE K E - DPSF TN g R GDEGG W AP KL K N - E K AL E L S 215
Cdd:PTZ00081 157 F N VIN GG K HAG NKLA - F QE FM I APV G APSFKE A LRMGAE V YHS L KSVIK K K y GLDA TN - V GDEGG F AP NI K D p E E AL D L L 234
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541357225 216 AK A CENL G FT l GK e V ALGV D F A S S TQWSE EK EK Y ------ VYERAGFVNSS EE QI E FAANII KKY KLIYA ED AVHEEAF E 289
Cdd:PTZ00081 235 VE A IKKA G YE - GK - V KICM D V A A S EFYDK EK KV Y dldfkn PNNDKSNKLTG EE LV E LYLDLV KKY PIVSI ED PFDQDDW E 312
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541357225 290 DM A E LT TKF - P K TLVT GDDL T VTN KDVLT KAI NM K S CNA AI LKVNQ A G SLYD A F E F AK V A NQ N NIKLIT SHRSGE ST D SH 368
Cdd:PTZ00081 313 AY A K LT AAI g Q K VQIV GDDL L VTN PTRIK KAI EK K A CNA LL LKVNQ I G TVTE A I E A AK L A QK N GWGVMV SHRSGE TE D TF 392
410 420 430
....*....|....*....|....*....|....*
gi 2541357225 369 IA HIGLATKSKML K V G I - VGG ER V AK L N E L I R LS E 402
Cdd:PTZ00081 393 IA DLVVGLGTGQI K T G A p CRS ER L AK Y N Q L L R IE E 427
PLN00191
PLN00191 enolase
1-402
1.56e-64
enolase
Pssm-ID: 215095 [Multi-domain]
Cd Length: 457
Bit Score: 213.42
E-value: 1.56e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541357225 1 M SK IT SING R I I YN SRG SK T I EVD IIS e N K FLG R VCA PSGAS V G K YEA VSFPNEKPE ------- ESLRML N - KN A QKF IG 72
Cdd:PLN00191 25 M AT IT KVKA R Q I ID SRG NP T V EVD LHT - S K GMF R AAV PSGAS T G I YEA LELRDGDKD ylgkgvl KAVKNV N e II A PAL IG 103
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541357225 73 LESS D LKTVHDTLRSI D QSS N YA K I G GALAF AVS I A SMESASKANDTS L FQ --- T L SSESSFKF P F P LG N ILG GG A HAG P 149
Cdd:PLN00191 104 MDPT D QTQIDNFMLEL D GTP N KG K L G ANAIL AVS L A VCKAGAAEKGVP L YK hia D L AGNKKLVL P V P AF N VIN GG S HAG N 183
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541357225 150 GTP d I QE IL I CAI G TKTIRD A IETNLA V HKE L RRILE K EDPSFTNGR GDEGG W AP KLK - N EKA LEL SAK A C E NL G F T l GK 228
Cdd:PLN00191 184 KLA - M QE FM I LPV G ASSFKE A MQMGSE V YHH L KAVIK K KYGQDACNV GDEGG F AP NIQ d N KEG LEL LKE A I E KA G Y T - GK 261
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541357225 229 e VAL G V D F A S S TQWSEE K E ----- K YVYERAGFVN S SE E Q I EFAANIIKK Y KLIYA ED AVHEEAF E DM A E LT TK f PKTLV 303
Cdd:PLN00191 262 - IKI G M D V A A S EFYTKD K K ydldf K EENNDGSNKK S GD E L I DLYKEFVSD Y PIVSI ED PFDQDDW E HW A K LT SL - EDVQI 339
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541357225 304 T GDDL T VTN KDVLT KAI NM K S CNA AI LKVNQ A G SLYDAF E FA K VANQNNIKLI TSHRSGE ST DS H IA H -- I GLAT KS km L 381
Cdd:PLN00191 340 V GDDL L VTN PKRVA KAI QE K A CNA LL LKVNQ I G TVTESI E AV K MSKAAGWGVM TSHRSGE TE DS F IA D la V GLAT GQ -- I 417
410 420
....*....|....*....|..
gi 2541357225 382 K V G I - VGG ER V AK L N E L I R LS E 402
Cdd:PLN00191 418 K T G A p CRS ER L AK Y N Q L L R IE E 439
Enolase_C
pfam00113 Enolase, C-terminal TIM barrel domain;
130-402
5.37e-54
Enolase, C-terminal TIM barrel domain;
Pssm-ID: 395063
Cd Length: 296
Bit Score: 181.14
E-value: 5.37e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541357225 130 S FKF P F P LG N ILG GG A HAG p GTPDI QE IL I CAI G TKTIRD A IETNLA V HKE L RRI L EKEDPSFTNGR GDEGG W AP K L K - N 208
Cdd:pfam00113 1 S YVL P V P MM N VIN GG S HAG - NNLAF QE FM I LPT G APSFSE A MRMGAE V YHH L KSV L KAKYGQSATNV GDEGG F AP N L Q s N 79
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541357225 209 EK AL E L SAK A C E NL G FTL gk EVALGV D F ASS TQWSEEKE KY VYERA G FVN ------ S S EEQIEFAANII KKY KLIYA ED A 282
Cdd:pfam00113 80 KE AL D L IVE A I E KA G YKG -- KIKIAM D V ASS EFYNKKDG KY DLDFK G EKS dkskkl T S AQLADLYEELV KKY PIVSI ED P 157
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541357225 283 VH E EAF E DMAE LT TKF - P K TLVT GDDLTVTN KDV L TK AI NM K SC NA AI LKVNQ A GSL YDAFEFA K V A NQNNIKLIT SHRS 361
Cdd:pfam00113 158 FD E DDW E AWKY LT ERL g D K VQIV GDDLTVTN PKR L KT AI EK K IA NA LL LKVNQ I GSL TESIAAV K M A KDAGWGVMV SHRS 237
250 260 270 280
....*....|....*....|....*....|....*....|..
gi 2541357225 362 GE ST D SH IA HIGLATKSKML K V G IVG - G ER V AK L N E L I R LS E 402
Cdd:pfam00113 238 GE TE D TT IA DLAVGLNAGQI K T G APC r S ER L AK Y N Q L L R IE E 279
Enolase_N
pfam03952 Enolase, N-terminal domain;
4-125
3.89e-30
Enolase, N-terminal domain;
Pssm-ID: 461105 [Multi-domain]
Cd Length: 131
Bit Score: 112.85
E-value: 3.89e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541357225 4 IT SING R I I YN SRG SK T I EV DIIS E NKFL GR VCA PSGAS V G KY EAV SFPNEKP -------- EESLRML N KN - A QKF IG LE 74
Cdd:pfam03952 1 IT KVKA R E I LD SRG NP T V EV EVTL E DGTF GR AAV PSGAS T G EH EAV ELRDGDK sryggkgv LKAVENV N EI i A PAL IG MD 80
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 2541357225 75 SS D LKTVHDT L RSI D QSS N YA K I G GALAFA VS I A SMES A SK A NDTS L FQT L 125
Cdd:pfam03952 81 AT D QRAIDRA L IEL D GTE N KS K L G ANAILG VS L A VAKA A AA A LGLP L YRY L 131
PRK08350
PRK08350 hypothetical protein; Provisional
1-402
3.55e-13
hypothetical protein; Provisional
Pssm-ID: 169397 [Multi-domain]
Cd Length: 341
Bit Score: 70.22
E-value: 3.55e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541357225 1 M SK I TS I N GR IIYNSR G SKTI EVD I I SENK F l GR VC AP SGASVGK Y ----- E AVS FPN E -- K PE eslrmlnknaqk F IG L 73
Cdd:PRK08350 1 M TV I EN I I GR VAVLRG G KYSV EVD V I TDSG F - GR FA AP IDENPSL Y iaeah R AVS EVD E ii G PE ------------ L IG F 67
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541357225 74 ES S DLKTVHDT L RS ID QSSNYAK IG GAL A F AVS I A SMES A SKANDTS L FQTLSSESSFKF P F P L gnilgggahagpgtpd 153
Cdd:PRK08350 68 DA S EQELIDSY L WE ID GTEDFSH IG ANT A L AVS V A VAKA A ANSKNMP L YSYIGGTFTTEL P V P I ---------------- 131
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541357225 154 iqeilicaigtkt IRD A IET N LAVHKEL R RIL E KE D PS ftngrg D EGGWAPKLKN E KA LE LSA KA C E NL G FT LG K EVALG 233
Cdd:PRK08350 132 ------------- LEF A EDE N FEYYVLV R DLM E IT D VV ------ D AVNKILENSK E VS LE GLS KA S E KA G DE LG L EVALG 192
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541357225 234 V dfasstqwseekekyvyeragf VNSS E EQI E FAA N IIKKYKLI Y AEDAVH EE A F edm A EL TTKFPKTLVT G DD L TV T N k 313
Cdd:PRK08350 193 I ---------------------- AQKR E MET E KVL N LVEDNNIA Y IKPIGD EE L F --- L EL IAGTHGVFID G EY L FR T R - 246
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541357225 314 DV L TK ainm KSC NA AIL K VNQA G S L Y D AFEFAKVANQNN I KL I TSHRSG ES T D SHIA H IGLATKSKML kvg IVGGER V A K 393
Cdd:PRK08350 247 NI L DR ---- RYY NA LSI K PINL G T L T D LYNLVNDVKSER I TP I LAEAKY ES A D EALP H LAVGLRCPAM --- LIHKDS V E K 319
....*....
gi 2541357225 394 L NEL I R LS E 402
Cdd:PRK08350 320 I NEL N R IA E 328
MLE_like
cd03315 Muconate lactonizing enzyme (MLE) like subgroup of the enolase superfamily. Enzymes of this ...
261-375
5.16e-04
Muconate lactonizing enzyme (MLE) like subgroup of the enolase superfamily. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and residues that can function as general acid/base catalysts, a Lys-X-Lys motif and another conserved lysine. Despite these conserved residues, the members of the MLE subgroup, like muconate lactonizing enzyme, o-succinylbenzoate synthase (OSBS) and N-acylamino acid racemase (NAAAR), catalyze different reactions.
Pssm-ID: 239431 [Multi-domain]
Cd Length: 265
Bit Score: 41.56
E-value: 5.16e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2541357225 261 EEQ I EFAANI i KKYK L I Y A E DAVHEEAF E DM A E L TTKFPKTLV t G D DLTV T NK D V l TKAINMKSCN A AIL K VNQA G S L YD 340
Cdd:cd03315 143 KQA I RALRAL - EDLG L D Y V E QPLPADDL E GR A A L ARATDTPIM - A D ESAF T PH D A - FRELALGAAD A VNI K TAKT G G L TK 219
90 100 110
....*....|....*....|....*....|....*..
gi 2541357225 341 A FEFAK VA NQNNIKLI -- TSHR SG ES T d SHI AH IGL A 375
Cdd:cd03315 220 A QRVLA VA EALGLPVM vg SMIE SG LG T - LAN AH LAA A 255
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
