NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|2543048348|ref|WP_298971531|]
View 

toxin-antitoxin system YwqK family antitoxin [uncultured Fusobacterium sp.]

Protein Classification

toxin-antitoxin system YwqK family antitoxin( domain architecture ID 11458243)

toxin-antitoxin (TA) system YwqK family antitoxin similar to YwqK (RtbO) antitoxin, the antitoxin component of the YwqJK (RtbNO) TA system that is encoded in the chromosome of Bacillus subtilis subsp. subtilis str. 168

PubMed:  31075979

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
YwqK COG2849
Antitoxin component YwqK of the YwqJK toxin-antitoxin module [Defense mechanisms];
27-152 7.55e-12

Antitoxin component YwqK of the YwqJK toxin-antitoxin module [Defense mechanisms];


:

Pssm-ID: 442097 [Multi-domain]  Cd Length: 163  Bit Score: 62.39  E-value: 7.55e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543048348  27 GEIREIKNTNTNINISTSKNYERKNGILYIDDVLanGKQEYKEKNGVVI-KGNYREGLADGLQERYYPSGKLYGKINIIN 105
Cdd:COG2849    34 SGVKEKTEDSYNEGGKLIKKKLGKGLGKYKKGKL--GEWKTYYPNGQLKsEGTYKNGKLEGEWKEYYENGKLKSEGNYKN 111

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 2543048348 106 NKVEGTETTYYENGKTISELNYTQGKLI-SGKVYYENGDLLSKIEGKK 152
Cdd:COG2849   112 GKLHGEWKEYYENGKLKEEGNYKNGKKDgVWKYYDENGKLVKEEEYKN 159
 
Name Accession Description Interval E-value
YwqK COG2849
Antitoxin component YwqK of the YwqJK toxin-antitoxin module [Defense mechanisms];
27-152 7.55e-12

Antitoxin component YwqK of the YwqJK toxin-antitoxin module [Defense mechanisms];


Pssm-ID: 442097 [Multi-domain]  Cd Length: 163  Bit Score: 62.39  E-value: 7.55e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543048348  27 GEIREIKNTNTNINISTSKNYERKNGILYIDDVLanGKQEYKEKNGVVI-KGNYREGLADGLQERYYPSGKLYGKINIIN 105
Cdd:COG2849    34 SGVKEKTEDSYNEGGKLIKKKLGKGLGKYKKGKL--GEWKTYYPNGQLKsEGTYKNGKLEGEWKEYYENGKLKSEGNYKN 111

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 2543048348 106 NKVEGTETTYYENGKTISELNYTQGKLI-SGKVYYENGDLLSKIEGKK 152
Cdd:COG2849   112 GKLHGEWKEYYENGKLKEEGNYKNGKKDgVWKYYDENGKLVKEEEYKN 159
 
Name Accession Description Interval E-value
YwqK COG2849
Antitoxin component YwqK of the YwqJK toxin-antitoxin module [Defense mechanisms];
27-152 7.55e-12

Antitoxin component YwqK of the YwqJK toxin-antitoxin module [Defense mechanisms];


Pssm-ID: 442097 [Multi-domain]  Cd Length: 163  Bit Score: 62.39  E-value: 7.55e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543048348  27 GEIREIKNTNTNINISTSKNYERKNGILYIDDVLanGKQEYKEKNGVVI-KGNYREGLADGLQERYYPSGKLYGKINIIN 105
Cdd:COG2849    34 SGVKEKTEDSYNEGGKLIKKKLGKGLGKYKKGKL--GEWKTYYPNGQLKsEGTYKNGKLEGEWKEYYENGKLKSEGNYKN 111

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 2543048348 106 NKVEGTETTYYENGKTISELNYTQGKLI-SGKVYYENGDLLSKIEGKK 152
Cdd:COG2849   112 GKLHGEWKEYYENGKLKEEGNYKNGKKDgVWKYYDENGKLVKEEEYKN 159
YwqK COG2849
Antitoxin component YwqK of the YwqJK toxin-antitoxin module [Defense mechanisms];
32-161 1.56e-09

Antitoxin component YwqK of the YwqJK toxin-antitoxin module [Defense mechanisms];


Pssm-ID: 442097 [Multi-domain]  Cd Length: 163  Bit Score: 55.84  E-value: 1.56e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543048348  32 IKNTNTNINISTSKNYERKNGILYIDDVLANGKQEYKEKNGVVIKGNYREGLADGLQERYYPSGKLYGKINIINNKVEGT 111
Cdd:COG2849    14 LSLKLKYELGDTLLEKNGYKSGVKEKTEDSYNEGGKLIKKKLGKGLGKYKKGKLGEWKTYYPNGQLKSEGTYKNGKLEGE 93

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2543048348 112 ETTYYENGKTISELNYTQGKLI-SGKVYYENGDLLSKIE---GKKI---TIFYSSGK 161
Cdd:COG2849    94 WKEYYENGKLKSEGNYKNGKLHgEWKEYYENGKLKEEGNyknGKKDgvwKYYDENGK 150
YwqK COG2849
Antitoxin component YwqK of the YwqJK toxin-antitoxin module [Defense mechanisms];
43-162 3.48e-03

Antitoxin component YwqK of the YwqJK toxin-antitoxin module [Defense mechanisms];


Pssm-ID: 442097 [Multi-domain]  Cd Length: 163  Bit Score: 37.74  E-value: 3.48e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543048348  43 TSKNYERKNGILYIDDVLANGKQEYKEKNGVVIKGNYREGLADGLQERYYPSGKLYGKINIINNKVEGTETTYYENGKTI 122
Cdd:COG2849     1 KKKEGLLKISKYLLSLKLKYELGDTLLEKNGYKSGVKEKTEDSYNEGGKLIKKKLGKGLGKYKKGKLGEWKTYYPNGQLK 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 2543048348 123 SELNYTQGKLI-SGKVYYENGDLLSKIE---GKK---ITIFYSSGKK 162
Cdd:COG2849    81 SEGTYKNGKLEgEWKEYYENGKLKSEGNyknGKLhgeWKEYYENGKL 127
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH