|
Name |
Accession |
Description |
Interval |
E-value |
| PRK06816 |
PRK06816 |
StlD/DarB family beta-ketosynthase; |
4-382 |
0e+00 |
|
StlD/DarB family beta-ketosynthase;
Pssm-ID: 235866 Cd Length: 378 Bit Score: 630.40 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543366770 4 KQVYIIKTASFFPNEPVSNDEIEEYLGYINNQTSKSKRIVLRNNGIKRRFYALKKDGTATHTNAQMASLAIRKLFNNNPE 83
Cdd:PRK06816 1 MNVYITSTGAFLPGEPVSNDEMEAYLGLINGKPSRARRIILRNNGIKTRHYALDPEGRPTHSNAQMAAEAIRDLLDDAGF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543366770 84 ELKKIELLSCGTSSPDQMMPSHSVMVHGWLpESNAIDVVSPSGNCCAGLHALKYAYMAVRAGDVSTAVVAGSERTSRILR 163
Cdd:PRK06816 81 SLGDIELLACGTSQPDQLMPGHASMVHGEL-GAPPIEVVSSAGVCAAGMMALKYAYLSVKAGESRNAVATASELASRWFR 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543366770 164 SDVFEDEVQKLTELEENPSISFEKEFLRWMLSDGAGAFLLSDKPNENEISLRIDWIEAVSYAHKVETCMYMGGDKLEDGS 243
Cdd:PRK06816 160 ASRFEAEEEKLAELEENPEIAFEKDFLRWMLSDGAGAVLLENKPRPDGLSLRIDWIDLRSYAGELPVCMYAGAEKNEDGS 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543366770 244 LKGYMDYTPEEIVSQSILSMKQDVKILRENIIELGFDKLKVVFDKRGHSVDEIQYFLPHMSSAFFKDKISNKLTENGMTI 323
Cdd:PRK06816 240 LKGWSDYPPEEAEAASALSLKQDVRLLNENIVVYTIKPLLELVDKRNLDPDDIDYFLPHYSSEYFREKIVELLAKAGFMI 319
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*....
gi 2543366770 324 PEEKWFTNLTSVGNVGAGSIYLMIDELLHSGKLKKGEKILIVVPESARFSYVYSMLTVC 382
Cdd:PRK06816 320 PEEKWFTNLATVGNTGSASIYIMLDELLNSGRLKPGQKILCFVPESGRFSTAFMLLTVV 378
|
|
| init_cond_enzymes |
cd00827 |
"initiating" condensing enzymes are a subclass of decarboxylating condensing enzymes, ... |
6-379 |
2.98e-61 |
|
"initiating" condensing enzymes are a subclass of decarboxylating condensing enzymes, including beta-ketoacyl [ACP] synthase, type III and polyketide synthases, type III, which include chalcone synthase and related enzymes. They are characterized by the utlization of CoA substrate primers, as well as the nature of their active site residues.
Pssm-ID: 238423 [Multi-domain] Cd Length: 324 Bit Score: 199.97 E-value: 2.98e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543366770 6 VYIIKTASFFPNEPVSNDEIEEYLGYInnqtskskrIVLRNNGIKRRFYALKKDGTAThtnaqMASLAIRKLFNNNPEEL 85
Cdd:cd00827 2 VGIEAIGAYLPRYRVDNEELAEGLGVD---------PGKYTTGIGQRHMAGDDEDVPT-----MAVEAARRALERAGIDP 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543366770 86 KKIELLSCGTSSPDQMMPSHSVMVHGWLPESN--AIDVvspSGNCCAGLHALKYAYMAVRAGDVSTAVVAGSERTSRILr 163
Cdd:cd00827 68 DDIGLLIVATESPIDKGKSAATYLAELLGLTNaeAFDL---KQACYGGTAALQLAANLVESGPWRYALVVASDIASYLL- 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543366770 164 sdvfedevqklteleenpsisFEKEFLRWMLSDGAGAFLLSDKPneneislRIDWIEAVSYAHKVETCMYMGGDKLEDGS 243
Cdd:cd00827 144 ---------------------DEGSALEPTLGDGAAAMLVSRNP-------GILAAGIVSTHSTSDPGYDFSPYPVMDGG 195
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543366770 244 LKGYMDYTPEEIVSQSILSmKQDVKILRENIIELGFDKLkvvfdKRGHSVDEIQYFLPHMSSA-FFKDKISNKLTENGMT 322
Cdd:cd00827 196 YPKPCKLAYAIRLTAEPAG-RAVFEAAHKLIAKVVRKAL-----DRAGLSEDIDYFVPHQPNGkKILEAVAKKLGGPPEK 269
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*..
gi 2543366770 323 IPEEKWfTNLTSVGNVGAGSIYLMIDELLHSGKLKKGEKILIvVPESARFSYVYSML 379
Cdd:cd00827 270 ASQTRW-ILLRRVGNMYAASILLGLASLLESGKLKAGDRVLL-FSYGSGFTAEAFVL 324
|
|
| FabH |
COG0332 |
3-oxoacyl-[acyl-carrier-protein] synthase III [Lipid transport and metabolism]; 3-oxoacyl- ... |
6-365 |
5.44e-42 |
|
3-oxoacyl-[acyl-carrier-protein] synthase III [Lipid transport and metabolism]; 3-oxoacyl-[acyl-carrier-protein] synthase III is part of the Pathway/BioSystem: Fatty acid biosynthesis
Pssm-ID: 440101 [Multi-domain] Cd Length: 323 Bit Score: 149.49 E-value: 5.44e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543366770 6 VYIIKTASFFPNEPVSNDEIEEYLGyinnqTSkSKRIVLRNnGIKRRFYALKKDGTAThtnaqMASLAIRKLFNN---NP 82
Cdd:COG0332 3 VRILGTGSYLPERVVTNDDLEKRLD-----TS-DEWIEERT-GIRERRIAAPDETTSD-----LAVEAARKALEAagiDP 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543366770 83 EElkkIELLSCGTSSPDQMMPSHSVMVHGWLPESN--AIDVvspSGNCCAGLHALKYAYMAVRAGDVSTAVVAGSERTSR 160
Cdd:COG0332 71 ED---IDLIIVATVTPDYLFPSTACLVQHKLGAKNaaAFDI---NAACSGFVYALSVAAALIRSGQAKNVLVVGAETLSR 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543366770 161 IlrsdvfedevqklteleenpsISFEKEFLRWMLSDGAGAFLLSDKPNENEIsLRIDWIEAVSYAHKVetCMYMGGDKLE 240
Cdd:COG0332 145 I---------------------VDWTDRSTCVLFGDGAGAVVLEASEEGPGI-LGSVLGSDGSGADLL--VVPAGGSRNP 200
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543366770 241 DGSLKGYMDYtpeeivsqsilsMKQDVKILRENIIELGFDKLKVVFDKRGHSVDEIQYFLPHMSSAFFKDKISNKLTeng 320
Cdd:COG0332 201 PSPVDEGDHY------------LRMDGREVFKFAVRNLPEVIREALEKAGLTLDDIDWFIPHQANLRIIEAVAKRLG--- 265
|
330 340 350 360
....*....|....*....|....*....|....*....|....*
gi 2543366770 321 mtIPEEKWFTNLTSVGNVGAGSIYLMIDELLHSGKLKKGEKILIV 365
Cdd:COG0332 266 --LPEEKVVVNIDRYGNTSAASIPLALDEALREGRIKPGDLVLLA 308
|
|
| ACP_syn_III_C |
pfam08541 |
3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal; This domain is found on ... |
286-365 |
3.05e-12 |
|
3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal; This domain is found on 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III EC:2.3.1.41, the enzyme responsible for initiating the chain of reactions of the fatty acid synthase in plants and bacteria.
Pssm-ID: 430060 Cd Length: 90 Bit Score: 62.13 E-value: 3.05e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543366770 286 FDKRGHSVDEIQYFLPHMSSAFFKDKISNKLtenGmtIPEEKWFTNLTSVGNVGAGSIYLMIDELLHSGKLKKGEKILIV 365
Cdd:pfam08541 1 LEKAGLTPEDIDWFVPHQANLRIIDAVAKRL---G--LPPEKVVVNLDEYGNTSAASIPLALDEAVEEGKLKPGDLVLLV 75
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK06816 |
PRK06816 |
StlD/DarB family beta-ketosynthase; |
4-382 |
0e+00 |
|
StlD/DarB family beta-ketosynthase;
Pssm-ID: 235866 Cd Length: 378 Bit Score: 630.40 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543366770 4 KQVYIIKTASFFPNEPVSNDEIEEYLGYINNQTSKSKRIVLRNNGIKRRFYALKKDGTATHTNAQMASLAIRKLFNNNPE 83
Cdd:PRK06816 1 MNVYITSTGAFLPGEPVSNDEMEAYLGLINGKPSRARRIILRNNGIKTRHYALDPEGRPTHSNAQMAAEAIRDLLDDAGF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543366770 84 ELKKIELLSCGTSSPDQMMPSHSVMVHGWLpESNAIDVVSPSGNCCAGLHALKYAYMAVRAGDVSTAVVAGSERTSRILR 163
Cdd:PRK06816 81 SLGDIELLACGTSQPDQLMPGHASMVHGEL-GAPPIEVVSSAGVCAAGMMALKYAYLSVKAGESRNAVATASELASRWFR 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543366770 164 SDVFEDEVQKLTELEENPSISFEKEFLRWMLSDGAGAFLLSDKPNENEISLRIDWIEAVSYAHKVETCMYMGGDKLEDGS 243
Cdd:PRK06816 160 ASRFEAEEEKLAELEENPEIAFEKDFLRWMLSDGAGAVLLENKPRPDGLSLRIDWIDLRSYAGELPVCMYAGAEKNEDGS 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543366770 244 LKGYMDYTPEEIVSQSILSMKQDVKILRENIIELGFDKLKVVFDKRGHSVDEIQYFLPHMSSAFFKDKISNKLTENGMTI 323
Cdd:PRK06816 240 LKGWSDYPPEEAEAASALSLKQDVRLLNENIVVYTIKPLLELVDKRNLDPDDIDYFLPHYSSEYFREKIVELLAKAGFMI 319
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*....
gi 2543366770 324 PEEKWFTNLTSVGNVGAGSIYLMIDELLHSGKLKKGEKILIVVPESARFSYVYSMLTVC 382
Cdd:PRK06816 320 PEEKWFTNLATVGNTGSASIYIMLDELLNSGRLKPGQKILCFVPESGRFSTAFMLLTVV 378
|
|
| init_cond_enzymes |
cd00827 |
"initiating" condensing enzymes are a subclass of decarboxylating condensing enzymes, ... |
6-379 |
2.98e-61 |
|
"initiating" condensing enzymes are a subclass of decarboxylating condensing enzymes, including beta-ketoacyl [ACP] synthase, type III and polyketide synthases, type III, which include chalcone synthase and related enzymes. They are characterized by the utlization of CoA substrate primers, as well as the nature of their active site residues.
Pssm-ID: 238423 [Multi-domain] Cd Length: 324 Bit Score: 199.97 E-value: 2.98e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543366770 6 VYIIKTASFFPNEPVSNDEIEEYLGYInnqtskskrIVLRNNGIKRRFYALKKDGTAThtnaqMASLAIRKLFNNNPEEL 85
Cdd:cd00827 2 VGIEAIGAYLPRYRVDNEELAEGLGVD---------PGKYTTGIGQRHMAGDDEDVPT-----MAVEAARRALERAGIDP 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543366770 86 KKIELLSCGTSSPDQMMPSHSVMVHGWLPESN--AIDVvspSGNCCAGLHALKYAYMAVRAGDVSTAVVAGSERTSRILr 163
Cdd:cd00827 68 DDIGLLIVATESPIDKGKSAATYLAELLGLTNaeAFDL---KQACYGGTAALQLAANLVESGPWRYALVVASDIASYLL- 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543366770 164 sdvfedevqklteleenpsisFEKEFLRWMLSDGAGAFLLSDKPneneislRIDWIEAVSYAHKVETCMYMGGDKLEDGS 243
Cdd:cd00827 144 ---------------------DEGSALEPTLGDGAAAMLVSRNP-------GILAAGIVSTHSTSDPGYDFSPYPVMDGG 195
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543366770 244 LKGYMDYTPEEIVSQSILSmKQDVKILRENIIELGFDKLkvvfdKRGHSVDEIQYFLPHMSSA-FFKDKISNKLTENGMT 322
Cdd:cd00827 196 YPKPCKLAYAIRLTAEPAG-RAVFEAAHKLIAKVVRKAL-----DRAGLSEDIDYFVPHQPNGkKILEAVAKKLGGPPEK 269
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*..
gi 2543366770 323 IPEEKWfTNLTSVGNVGAGSIYLMIDELLHSGKLKKGEKILIvVPESARFSYVYSML 379
Cdd:cd00827 270 ASQTRW-ILLRRVGNMYAASILLGLASLLESGKLKAGDRVLL-FSYGSGFTAEAFVL 324
|
|
| FabH |
COG0332 |
3-oxoacyl-[acyl-carrier-protein] synthase III [Lipid transport and metabolism]; 3-oxoacyl- ... |
6-365 |
5.44e-42 |
|
3-oxoacyl-[acyl-carrier-protein] synthase III [Lipid transport and metabolism]; 3-oxoacyl-[acyl-carrier-protein] synthase III is part of the Pathway/BioSystem: Fatty acid biosynthesis
Pssm-ID: 440101 [Multi-domain] Cd Length: 323 Bit Score: 149.49 E-value: 5.44e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543366770 6 VYIIKTASFFPNEPVSNDEIEEYLGyinnqTSkSKRIVLRNnGIKRRFYALKKDGTAThtnaqMASLAIRKLFNN---NP 82
Cdd:COG0332 3 VRILGTGSYLPERVVTNDDLEKRLD-----TS-DEWIEERT-GIRERRIAAPDETTSD-----LAVEAARKALEAagiDP 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543366770 83 EElkkIELLSCGTSSPDQMMPSHSVMVHGWLPESN--AIDVvspSGNCCAGLHALKYAYMAVRAGDVSTAVVAGSERTSR 160
Cdd:COG0332 71 ED---IDLIIVATVTPDYLFPSTACLVQHKLGAKNaaAFDI---NAACSGFVYALSVAAALIRSGQAKNVLVVGAETLSR 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543366770 161 IlrsdvfedevqklteleenpsISFEKEFLRWMLSDGAGAFLLSDKPNENEIsLRIDWIEAVSYAHKVetCMYMGGDKLE 240
Cdd:COG0332 145 I---------------------VDWTDRSTCVLFGDGAGAVVLEASEEGPGI-LGSVLGSDGSGADLL--VVPAGGSRNP 200
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543366770 241 DGSLKGYMDYtpeeivsqsilsMKQDVKILRENIIELGFDKLKVVFDKRGHSVDEIQYFLPHMSSAFFKDKISNKLTeng 320
Cdd:COG0332 201 PSPVDEGDHY------------LRMDGREVFKFAVRNLPEVIREALEKAGLTLDDIDWFIPHQANLRIIEAVAKRLG--- 265
|
330 340 350 360
....*....|....*....|....*....|....*....|....*
gi 2543366770 321 mtIPEEKWFTNLTSVGNVGAGSIYLMIDELLHSGKLKKGEKILIV 365
Cdd:COG0332 266 --LPEEKVVVNIDRYGNTSAASIPLALDEALREGRIKPGDLVLLA 308
|
|
| KAS_III |
cd00830 |
Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty ... |
6-365 |
1.44e-35 |
|
Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl carrier protein (ACP) with acyl-ACP. KASIII initiates this process by specifically using acetyl-CoA over acyl-CoA.
Pssm-ID: 238426 [Multi-domain] Cd Length: 320 Bit Score: 132.28 E-value: 1.44e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543366770 6 VYIIKTASFFPNEPVSNDEIEEYLGyinnqtSKSKRIVLRNnGIKRRFYALKKDGTAThtnaqMASLAIRKLFNNNPEEL 85
Cdd:cd00830 2 ARILGIGSYLPERVVTNDELEKRLD------TSDEWIRTRT-GIRERRIADPGETTSD-----LAVEAAKKALEDAGIDA 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543366770 86 KKIELLSCGTSSPDQMMPSHSVMVHGWLPESN--AIDVvspsGNCCAG-LHALKYAYMAVRAGDVSTAVVAGSERTSRIL 162
Cdd:cd00830 70 DDIDLIIVATSTPDYLFPATACLVQARLGAKNaaAFDI----NAACSGfLYGLSTAAGLIRSGGAKNVLVVGAETLSRIL 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543366770 163 RSDvfedevqklteleeNPSISFEkeflrwmLSDGAGAFLLSDKPNENEIsLRIDWIeavSYAHKVETCMYMGGDkledg 242
Cdd:cd00830 146 DWT--------------DRSTAVL-------FGDGAGAVVLEATEEDPGI-LDSVLG---SDGSGADLLTIPAGG----- 195
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543366770 243 slkgyMDYTPEEIVSQSILSMKQDVKILRENIIELGfDKLKVVFDKRGHSVDEIQYFLPHMSSAFFKDKISNKLtenGmt 322
Cdd:cd00830 196 -----SRSPFEDAEGGDPYLVMDGREVFKFAVRLMP-ESIEEALEKAGLTPDDIDWFVPHQANLRIIEAVAKRL---G-- 264
|
330 340 350 360
....*....|....*....|....*....|....*....|...
gi 2543366770 323 IPEEKWFTNLTSVGNVGAGSIYLMIDELLHSGKLKKGEKILIV 365
Cdd:cd00830 265 LPEEKVVVNLDRYGNTSAASIPLALDEAIEEGKLKKGDLVLLL 307
|
|
| PRK09352 |
PRK09352 |
beta-ketoacyl-ACP synthase 3; |
1-365 |
2.47e-20 |
|
beta-ketoacyl-ACP synthase 3;
Pssm-ID: 236475 [Multi-domain] Cd Length: 319 Bit Score: 90.52 E-value: 2.47e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543366770 1 MSAKqvyIIKTASFFPNEPVSNDEIEEYLgyinnQTSkSKRIVLRNnGIKRRFYALKKDGTAThtnaqMASLAIRKLFNN 80
Cdd:PRK09352 2 MYAK---ILGTGSYLPERVVTNDDLEKMV-----DTS-DEWIVTRT-GIKERRIAAPDETTSD-----LATEAAKKALEA 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543366770 81 ---NPEElkkIELLSCGTSSPDQMMPSHSVMVHGWLPESNAI--DVVSpsgnCCAG-LHALKYAYMAVRAGDVSTAVVAG 154
Cdd:PRK09352 67 agiDPED---IDLIIVATTTPDYAFPSTACLVQARLGAKNAAafDLSA----ACSGfVYALSTADQFIRSGAYKNVLVIG 139
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543366770 155 SERTSRILrsDvFEDevqklteleENPSISFekeflrwmlSDGAGAFLLsdkpneneislridwiEAVSYAHKVETCMYM 234
Cdd:PRK09352 140 AEKLSRIV--D-WTD---------RSTCVLF---------GDGAGAVVL----------------GASEEPGILSTHLGS 182
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543366770 235 ggdkleDGSLKG--YMDYTPEEI-VSQSILSM------KQDVKILRENIIElgfdklkvVFDKRGHSVDEIQYFLPH--- 302
Cdd:PRK09352 183 ------DGSYGDllYLPGGGSRGpASPGYLRMegrevfKFAVRELAKVARE--------ALEAAGLTPEDIDWLVPHqan 248
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2543366770 303 ---MssaffkDKISNKLtengmTIPEEKWFTNLTSVGNVGAGSIYLMIDELLHSGKLKKGEKILIV 365
Cdd:PRK09352 249 lriI------DATAKKL-----GLPMEKVVVTVDKYGNTSAASIPLALDEAVRDGRIKRGDLVLLE 303
|
|
| PRK12879 |
PRK12879 |
3-oxoacyl-(acyl carrier protein) synthase III; Reviewed |
16-365 |
1.58e-16 |
|
3-oxoacyl-(acyl carrier protein) synthase III; Reviewed
Pssm-ID: 237245 [Multi-domain] Cd Length: 325 Bit Score: 79.52 E-value: 1.58e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543366770 16 PNEPVSNDEIEEYLGyinnqTSkSKRIVLRNnGIKRRFYALKKDGTAThtnaqMASLAIRKLFNNNPEELKKIELLSCGT 95
Cdd:PRK12879 15 PPRVLTNDDLETFID-----TS-DEWIVQRT-GIKERRIAHVEEYTSD-----LAIKAAERALARAGLDAEDIDLIIVAT 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543366770 96 SSPDQMMPSHSVMVHGWL--PESNAIDVvspSGNCCAGLHALKYAYMAVRAGDVSTAVVAGSERTSRILrsDvFEDEvqk 173
Cdd:PRK12879 83 TTPDYLFPSTASQVQARLgiPNAAAFDI---NAACAGFLYGLETANGLITSGLYKKVLVIGAERLSKVT--D-YTDR--- 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543366770 174 lteleeNPSISFekeflrwmlSDGAGAFLLSdkPNENEISLridwIEAV--SYAHKVETCMYMG-GDKL--EDGSLKGYM 248
Cdd:PRK12879 154 ------TTCILF---------GDGAGAVVLE--ATENEPGF----IDYVlgTDGDGGDILYRTGlGTTMdrDALSGDGYI 212
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543366770 249 DYTPEEIVSQSILSMkqdVKILREniielgfdklkvVFDKRGHSVDEIQYFLPHMSSAFFKDKISNKltengMTIPEEKW 328
Cdd:PRK12879 213 VQNGREVFKWAVRTM---PKGARQ------------VLEKAGLTKDDIDWVIPHQANLRIIESLCEK-----LGIPMEKT 272
|
330 340 350
....*....|....*....|....*....|....*..
gi 2543366770 329 FTNLTSVGNVGAGSIYLMIDELLHSGKLKKGEKILIV 365
Cdd:PRK12879 273 LVSVEYYGNTSAATIPLALDLALEQGKIKPGDTLLLY 309
|
|
| PRK05963 |
PRK05963 |
beta-ketoacyl-ACP synthase III; |
16-364 |
6.35e-14 |
|
beta-ketoacyl-ACP synthase III;
Pssm-ID: 180328 [Multi-domain] Cd Length: 326 Bit Score: 72.06 E-value: 6.35e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543366770 16 PNEPVSNDEIEEYLGYinnqtskSKRIVLRNNGIKRRFYAlKKDGTATHTNAQMASLAIRklfnNNPEELKKIELLSCGT 95
Cdd:PRK05963 14 PDRRVENAEIEAQLGL-------ETGWIERRTGIRCRRWA-APDETLSDLAASAGDMALS----DAGIERSDIALTLLAT 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543366770 96 SSPDQMMPSHSVMVHGWL--PESNAIDVvspSGNCCAGLHALKYAYMAVRAGDVSTAVVAGSERTSRIlrsdvfedevqk 173
Cdd:PRK05963 82 STPDHLLPPSAPLLAHRLglQNSGAIDL---AGACAGFLYALVLADGFVRAQGKPVLVVAANILSRRI------------ 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543366770 174 lTELEENPSISFekeflrwmlSDGAGAFLLSDKPNENEISLridwieavsyahkvetcmymGGDKLEDGSlkGY------ 247
Cdd:PRK05963 147 -NMAERASAVLF---------ADAAGAVVLAPSAKANSGVL--------------------GSQLISDGS--HYdlikip 194
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543366770 248 -----MDYTPEEIVSQSILSMkQDVKILRENIIELGFDKLKVVFDKRGHSVDEIQYFLPHMSSAffkdKISNKLTENgMT 322
Cdd:PRK05963 195 aggsaRPFAPERDASEFLMTM-QDGRAVFTEAVRMMSGASQNVLASAAMTPQDIDRFFPHQANA----RIVDKVCET-IG 268
|
330 340 350 360
....*....|....*....|....*....|....*....|..
gi 2543366770 323 IPEEKWFTNLTSVGNVGAGSIYLMIDELLHSGKLKKGEKILI 364
Cdd:PRK05963 269 IPRAKAASTLETYGNSSAATIPLSLSLANLEQPLREGERLLF 310
|
|
| PLN02326 |
PLN02326 |
3-oxoacyl-[acyl-carrier-protein] synthase III |
8-362 |
2.42e-12 |
|
3-oxoacyl-[acyl-carrier-protein] synthase III
Pssm-ID: 215185 Cd Length: 379 Bit Score: 67.45 E-value: 2.42e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543366770 8 IIKTASFFPNEPVSNDEIEEYLgyinnQTSkSKRIVLRNnGIKRRfYALKKDGTATHTNAQMASLAIrKLFNNNPEElkk 87
Cdd:PLN02326 50 LVGCGSAVPKLLITNDDLSKLV-----DTS-DEWIATRT-GIRNR-RVLSGDETLTSLAVEAAKKAL-EMAGVDPED--- 117
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543366770 88 IELLSCGTSSPDQMMPShSVMVHGWLPESNAI--DVVSpsgnCCAG-LHALKYAYMAVRAGDVSTAVVAGSERTSRilrs 164
Cdd:PLN02326 118 VDLVLLCTSSPDDLFGS-APQVQAALGCTNALafDLTA----ACSGfVLGLVTAARFIRGGGYKNVLVIGADALSR---- 188
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543366770 165 dvFEDEVQKLTeleenpSISFekeflrwmlSDGAGAFLLSDKPNENEISLRIDwIEAVSYAHKVETCMYMGGDKLEDGSL 244
Cdd:PLN02326 189 --YVDWTDRGT------CILF---------GDGAGAVVLQACDDDEDGLLGFD-MHSDGNGHKHLHATFKGEDDDSSGGN 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543366770 245 KGYMDYTPEEIVSQSILSMK-QDVKILRENIIELGFDKlkvVFDKRGHSVDEIQYFLPHMSSAFFKDKISNKLTengmtI 323
Cdd:PLN02326 251 TNGVGDFPPKKASYSCIQMNgKEVFKFAVRCVPQVIES---ALQKAGLTAESIDWLLLHQANQRIIDAVAQRLG-----I 322
|
330 340 350
....*....|....*....|....*....|....*....
gi 2543366770 324 PEEKWFTNLTSVGNVGAGSIYLMIDELLHSGKLKKGEKI 362
Cdd:PLN02326 323 PPEKVISNLANYGNTSAASIPLALDEAVRSGKVKKGDVI 361
|
|
| ACP_syn_III_C |
pfam08541 |
3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal; This domain is found on ... |
286-365 |
3.05e-12 |
|
3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal; This domain is found on 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III EC:2.3.1.41, the enzyme responsible for initiating the chain of reactions of the fatty acid synthase in plants and bacteria.
Pssm-ID: 430060 Cd Length: 90 Bit Score: 62.13 E-value: 3.05e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543366770 286 FDKRGHSVDEIQYFLPHMSSAFFKDKISNKLtenGmtIPEEKWFTNLTSVGNVGAGSIYLMIDELLHSGKLKKGEKILIV 365
Cdd:pfam08541 1 LEKAGLTPEDIDWFVPHQANLRIIDAVAKRL---G--LPPEKVVVNLDEYGNTSAASIPLALDEAVEEGKLKPGDLVLLV 75
|
|
| fabH |
CHL00203 |
3-oxoacyl-acyl-carrier-protein synthase 3; Provisional |
6-364 |
6.34e-12 |
|
3-oxoacyl-acyl-carrier-protein synthase 3; Provisional
Pssm-ID: 164577 [Multi-domain] Cd Length: 326 Bit Score: 66.12 E-value: 6.34e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543366770 6 VYIIKTASFFPNEPVSNDEIEEYLgyinnQTSkSKRIVLRNnGIKRRFYAlkkdGTATHTNAQMASLAIRKLF--NNNPE 83
Cdd:CHL00203 3 VHILSTGSSVPNFSVENQQFEDII-----ETS-DHWISTRT-GIKKRHLA----PSSTSLTKLAAEAANKALDkaHMDPL 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543366770 84 ElkkIELLSCGTSSPDQMMPSHS-VMVHGWLPESNAIDVVSpsgnCCAG-LHALKYAYMAVRAGDVSTAVVAGSERTSR- 160
Cdd:CHL00203 72 E---IDLIILATSTPDDLFGSASqLQAEIGATRAVAFDITA----ACSGfILALVTATQFIQNGSYKNILVVGADTLSKw 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543366770 161 ILRSDvfedevqklteleENPSISFekeflrwmlSDGAGAFLLSdKPNENEIslridwieavsyahkvetcmyMGGDKLE 240
Cdd:CHL00203 145 IDWSD-------------RKTCILF---------GDGAGAAIIG-ASYENSI---------------------LGFKLCT 180
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543366770 241 DGSLKGYMDYTPEEIVSQSILSMK------QDVKILRENIIELGFDKLKVVFDK----RGHSVDEIQYFLPHMSSAFFKD 310
Cdd:CHL00203 181 DGKLNSHLQLMNKPVNNQSFGTTKlpqgqyQSISMNGKEVYKFAVFQVPAVIIKclnaLNISIDEVDWFILHQANKRILE 260
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....
gi 2543366770 311 KISNKLTengmtIPEEKWFTNLTSVGNVGAGSIYLMIDELLHSGKLKKGEKILI 364
Cdd:CHL00203 261 AIANRLS-----VPNSKMITNLEKYGNTSAASIPLALDEAIQNNKIQPGQIIVL 309
|
|
| PRK07204 |
PRK07204 |
beta-ketoacyl-ACP synthase III; |
6-365 |
3.82e-08 |
|
beta-ketoacyl-ACP synthase III;
Pssm-ID: 235964 Cd Length: 329 Bit Score: 54.46 E-value: 3.82e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543366770 6 VYIIKTASFFPNEPVSNDEIEEYLGYINNQtskskriVLRNNGIKRRFYAlkkdgtATHTNAQMASLAIRKLFNNNPEEL 85
Cdd:PRK07204 5 ISIKGIGTYLPKRKVDSLELDKKLDLPEGW-------VLKKSGVKTRHFV------DGETSSYMGAEAAKKAVEDAKLTL 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543366770 86 KKIELLSCGTSSPDQMMPSHSVMVHGWLPESNaidvvspSGNCCAGLHALKYAYmaVRAGDVSTAVVAGSeRTSRIL--R 163
Cdd:PRK07204 72 DDIDCIICASGTIQQAIPCTASLIQEQLGLQH-------SGIPCFDINSTCLSF--ITALDTISYAIECG-RYKRVLiiS 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543366770 164 SDVfedevqklteleenPSISfekefLRW-------MLSDGAGAFLLSdkpNENEISlRIDWIEAVSYAHKVETCMYMGG 236
Cdd:PRK07204 142 SEI--------------SSVG-----LNWgqnesciLFGDGAAAVVIT---KGDHSS-RILASHMETYSSGAHLSEIRGG 198
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543366770 237 dkledGSLKGYMDYTpEEIVSQSILSMK-QDVKILRENIIELGFDKLkvvFDKRGHSVDEIQYFLPHMSSAFFKDKISNK 315
Cdd:PRK07204 199 -----GTMIHPREYS-EERKEDFLFDMNgRAIFKLSSKYLMKFIDKL---LMDAGYTLADIDLIVPHQASGPAMRLIRKK 269
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|
gi 2543366770 316 LTengmtIPEEKWFTNLTSVGNVGAGSIYLMIDELLHSGKLKKGEKILIV 365
Cdd:PRK07204 270 LG-----VDEERFVTIFEDHGNMIAASIPVALFEAIKQKKVQRGNKILLL 314
|
|
| PRK12880 |
PRK12880 |
beta-ketoacyl-ACP synthase III; |
22-350 |
1.59e-07 |
|
beta-ketoacyl-ACP synthase III;
Pssm-ID: 171793 Cd Length: 353 Bit Score: 52.66 E-value: 1.59e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543366770 22 NDEIEEYLGYINNQTSKSKRIVlrnnGIKRRFYALKKdgTATHTNAQMASLAIRKLFNNNPEELKKIELLscgTSSPDQM 101
Cdd:PRK12880 25 DDELESVFSNDIKTLKRMKKVI----GLNTRYICDEN--TCVSDLGKHAANTLLQGLNIDKNSLDALIVV---TQSPDFF 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543366770 102 MPSHSVMVHGWL---PESNAIDVvspsGNCCAG-LHALKYAYMAVRAGDVSTAVVAGSERTSRILRSD-----VFEDEVQ 172
Cdd:PRK12880 96 MPSTACYLHQLLnlsSKTIAFDL----GQACAGyLYGLFVAHSLIQSGLGKILLICGDTLSKFIHPKNmnlapIFGDGVS 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543366770 173 -KLTELEENPSISFE-----KEFLRWMLSDGAGAFLLSDKPNENEIsLRIDWIEAVSYahkvetcMYMGGdkledgslkg 246
Cdd:PRK12880 172 aTLIEKTDFNEAFFElgsdgKYFDKLIIPKGAMRIPKADIFNDDSL-MQTEEFRQLEN-------LYMDG---------- 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543366770 247 ymdytpEEIVSQSILSMKQDVKilreNIIELGfdklkvvfdkrGHSVDEIQYFLPHMSSAFFKDKISNKLTENGMTIPEe 326
Cdd:PRK12880 234 ------ANIFNMALECEPKSFK----EILEFS-----------KVDEKDIAFHLFHQSNAYLVDCIKEELKLNDDKVPN- 291
|
330 340
....*....|....*....|....
gi 2543366770 327 kwFTnLTSVGNVGAGSIYLMIDEL 350
Cdd:PRK12880 292 --FI-MEKYANLSACSLPALLCEL 312
|
|
| ACP_syn_III |
pfam08545 |
3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III; This domain is found on 3-Oxoacyl- ... |
129-204 |
3.70e-05 |
|
3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III; This domain is found on 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III EC:2.3.1.180, the enzyme responsible for initiating the chain of reactions of the fatty acid synthase in plants and bacteria.
Pssm-ID: 430064 [Multi-domain] Cd Length: 80 Bit Score: 41.73 E-value: 3.70e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2543366770 129 CAG-LHALKYAYMAVRAGDVSTAVVAGSERTSRILrsDvfedevqkltelEENPSISFekeflrwMLSDGAGAFLLS 204
Cdd:pfam08545 7 CSGfVYALSTAAALIRSGRAKNVLVIGAETLSKIL--D------------WTDRSTAV-------LFGDGAGAVVLE 62
|
|
| SCP-x_thiolase |
cd00829 |
Thiolase domain associated with sterol carrier protein (SCP)-x isoform and related proteins; ... |
67-169 |
8.19e-04 |
|
Thiolase domain associated with sterol carrier protein (SCP)-x isoform and related proteins; SCP-2 has multiple roles in intracellular lipid circulation and metabolism. The N-terminal presequence in the SCP-x isoform represents a peroxisomal 3-ketacyl-Coa thiolase specific for branched-chain acyl CoAs, which is proteolytically cleaved from the sterol carrier protein.
Pssm-ID: 238425 [Multi-domain] Cd Length: 375 Bit Score: 41.09 E-value: 8.19e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543366770 67 AQMASLAIRKLFNNNPEELKKIELLSCGT--SSPDQMMPSHSV-MVHGWLPesnaIDVVSPSGNCCAGLHALKYAYMAVR 143
Cdd:cd00829 17 LELAAEAARAALDDAGLEPADIDAVVVGNaaGGRFQSFPGALIaEYLGLLG----KPATRVEAAGASGSAAVRAAAAAIA 92
|
90 100
....*....|....*....|....*.
gi 2543366770 144 AGDVSTAVVAGSERTSRILRSDVFED 169
Cdd:cd00829 93 SGLADVVLVVGAEKMSDVPTGDEAGG 118
|
|
| thiolase |
cd00751 |
Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of ... |
62-160 |
3.48e-03 |
|
Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and eukaryotes (cytosol, microbodies and mitochondria). There are 2 functional different classes: thiolase-I (3-ketoacyl-CoA thiolase) and thiolase-II (acetoacetyl-CoA thiolase). Thiolase-I can cleave longer fatty acid molecules and plays an important role in the beta-oxidative degradation of fatty acids. Thiolase-II has a high substrate specificity. Although it can cleave acetoacyl-CoA, its main function is the synthesis of acetoacyl-CoA from two molecules of acetyl-CoA, which gives it importance in several biosynthetic pathways.
Pssm-ID: 238383 [Multi-domain] Cd Length: 386 Bit Score: 39.00 E-value: 3.48e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543366770 62 ATHTNAQMASLAIRKLFNNNPEELKKIE--LLSCGTSSPDQMMPSHSVMVHGWLPES---NAIDVVspsgnCCAGLHALK 136
Cdd:cd00751 18 KDVSADDLGAAVIKALLERAGLDPEEVDdvIMGNVLQAGEGQNPARQAALLAGLPESvpaTTVNRV-----CGSGLQAVA 92
|
90 100
....*....|....*....|....
gi 2543366770 137 YAYMAVRAGDVSTAVVAGSERTSR 160
Cdd:cd00751 93 LAAQSIAAGEADVVVAGGVESMSR 116
|
|
| cond_enzymes |
cd00327 |
Condensing enzymes; Family of enzymes that catalyze a (decarboxylating or non-decarboxylating) ... |
87-156 |
3.59e-03 |
|
Condensing enzymes; Family of enzymes that catalyze a (decarboxylating or non-decarboxylating) Claisen-like condensation reaction. Members are share strong structural similarity, and are involved in the synthesis and degradation of fatty acids, and the production of polyketides, a diverse group of natural products.
Pssm-ID: 238201 [Multi-domain] Cd Length: 254 Bit Score: 38.58 E-value: 3.59e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2543366770 87 KIELLSCGTSSPDQMMPSHS--VMVHGWLPESNAIDVvspSGNCCAGLHALKYAYMAVRAGDVSTAVVAGSE 156
Cdd:cd00327 28 PIVGVIVGTTGGSGEFSGAAgqLAYHLGISGGPAYSV---NQACATGLTALALAVQQVQNGKADIVLAGGSE 96
|
|
| |
