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Conserved domains on  [gi|2543669053|ref|WP_299536196|]
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isochorismate synthase [uncultured Streptomyces sp.]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK06923 super family cl35516
isochorismate synthase DhbC; Validated
 21-397 1.15e-160

isochorismate synthase DhbC; Validated


The actual alignment was detected with superfamily member PRK06923:

Pssm-ID: 235886 [Multi-domain]  Cd Length: 399  Bit Score: 457.27  E-value: 1.15e-160
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053  21 ATALLDAYRPGTDRFLATPRLTLLCTGAAAELAEDD-RPVTERVQELLDARRLAGDPEPIVVGALPFDPSGRPALVVPET 99
Cdd:PRK06923   11 SEKLLEDYKTESSFFFASPTRTILAEGEFTTVKHHEiESFPERVQAVLRNAKQAGNPNPIVVGALPFDRRKEVQLIVPEY 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053 100 VRRAPALREDPLIALpapEPSDGGGWHVREVPAAADYRDAVAAAVDRINAGELSKVVLARTLELTGPQDADLPAMLGRLA 179
Cdd:PRK06923   91 SRISERLQLDTTNHL---EINRNLTFEMTPVPDPEVYMNGVKQGIAKIQDGDLKKIVLSRSLDVKSSEKIDKQKLLRELA 167

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053 180 RRDPGGYTFAV--PSG---PRTTLVGASPELLVARSGGVLVANPLAGSTPRSADLAEDVRRAAALLESAKDIHEHAVVVD 254
Cdd:PRK06923  168 EHNKHGYTFAVnlPKDeneNSKTLIGASPELLVSRHGMQVISNPLAGSRPRSDDPVEDKRRAEELLSSPKDLHEHAVVVE 247

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053 255 AVRAALAPFCTELDVPERPTLVRTATMWHLSTTVTGRIADPGTTALDLASALHPTPAVCGTPDDTARRVIADSEPFDRGL 334
Cdd:PRK06923  248 AVAAALRPYCHTLHVPEKPSVIHTEAMWHLSTEVKGELKDPNTSSLELAIALHPTPAVCGTPTEEAREAIQQIEPFDREF 327

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2543669053 335 YTGMVGWQDADGDGEWVVTLRCAEAEGATLRLFAGAGVVGDSSPQAETDETGAKFRTFLNAVG 397
Cdd:PRK06923  328 FTGMLGWSDLNGDGEWIVTIRCAEVEENTLRLYAGAGVVAESKPEDELAETSAKFQTMLKAMG 390
 
Name Accession Description Interval E-value
PRK06923 PRK06923
isochorismate synthase DhbC; Validated
 21-397 1.15e-160

isochorismate synthase DhbC; Validated


Pssm-ID: 235886 [Multi-domain]  Cd Length: 399  Bit Score: 457.27  E-value: 1.15e-160
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053  21 ATALLDAYRPGTDRFLATPRLTLLCTGAAAELAEDD-RPVTERVQELLDARRLAGDPEPIVVGALPFDPSGRPALVVPET 99
Cdd:PRK06923   11 SEKLLEDYKTESSFFFASPTRTILAEGEFTTVKHHEiESFPERVQAVLRNAKQAGNPNPIVVGALPFDRRKEVQLIVPEY 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053 100 VRRAPALREDPLIALpapEPSDGGGWHVREVPAAADYRDAVAAAVDRINAGELSKVVLARTLELTGPQDADLPAMLGRLA 179
Cdd:PRK06923   91 SRISERLQLDTTNHL---EINRNLTFEMTPVPDPEVYMNGVKQGIAKIQDGDLKKIVLSRSLDVKSSEKIDKQKLLRELA 167

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053 180 RRDPGGYTFAV--PSG---PRTTLVGASPELLVARSGGVLVANPLAGSTPRSADLAEDVRRAAALLESAKDIHEHAVVVD 254
Cdd:PRK06923  168 EHNKHGYTFAVnlPKDeneNSKTLIGASPELLVSRHGMQVISNPLAGSRPRSDDPVEDKRRAEELLSSPKDLHEHAVVVE 247

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053 255 AVRAALAPFCTELDVPERPTLVRTATMWHLSTTVTGRIADPGTTALDLASALHPTPAVCGTPDDTARRVIADSEPFDRGL 334
Cdd:PRK06923  248 AVAAALRPYCHTLHVPEKPSVIHTEAMWHLSTEVKGELKDPNTSSLELAIALHPTPAVCGTPTEEAREAIQQIEPFDREF 327

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2543669053 335 YTGMVGWQDADGDGEWVVTLRCAEAEGATLRLFAGAGVVGDSSPQAETDETGAKFRTFLNAVG 397
Cdd:PRK06923  328 FTGMLGWSDLNGDGEWIVTIRCAEVEENTLRLYAGAGVVAESKPEDELAETSAKFQTMLKAMG 390
MenF COG1169
Isochorismate synthase EntC [Coenzyme transport and metabolism, Secondary metabolites ...
 40-397 6.40e-137

Isochorismate synthase EntC [Coenzyme transport and metabolism, Secondary metabolites biosynthesis, transport and catabolism]; Isochorismate synthase EntC is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440783 [Multi-domain]  Cd Length: 353  Bit Score: 395.29  E-value: 6.40e-137
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053  40 RLTLLCTGAAAEL----AEDDRPVTERVQELLDARRLAGdPEPIVVGALPFDP---SGRPALVVPETVRRapalredpli 112
Cdd:COG1169    11 GEGLAGLGEAARFeapgPDRFAALAAAWQALLADAALAG-TGPRAFGGFAFDPdspAPAARLVLPRLLLR---------- 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053 113 alpapepsdgggWHVREVPAAADYRDAVAAAVDRINAGELSKVVLARTLELTGPQDADLPAMLGRLARRDPGGYTFAVPS 192
Cdd:COG1169    80 ------------RSRRGVPDPAEWREAVAQALEAIRAGELDKVVLARALDLTLDEPIDPRALLARLRRRNPDCYTFAVEL 147

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053 193 GPRTTLVGASPELLVARSGGVLVANPLAGSTPRSADLAEDVRRAAALLESAKDIHEHAVVVDAVRAALAPFCTELDVPER 272
Cdd:COG1169   148 GAGDGFVGASPERLVRRRGGQLTTEALAGTAPRGADPEEDAALAAALLASEKDRREHALVVDSIREALAPLCSSLDVPEE 227

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053 273 PTLVRTATMWHLSTTVTGRIaDPGTTALDLASALHPTPAVCGTPDDTARRVIADSEPFDRGLYTGMVGWQDADGDGEWVV 352
Cdd:COG1169   228 PELLRLRNVQHLATPITGTL-DPGVSALDLAAALHPTPAVGGTPREAALALIRELEPFDRGWYAGPVGWVDADGDGEFAV 306

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*
gi 2543669053 353 TLRCAEAEGATLRLFAGAGVVGDSSPQAETDETGAKFRTFLNAVG 397
Cdd:COG1169   307 AIRSALIDGNRARLFAGAGIVAGSDPEAEWAETEAKLRTMLRALG 351
Chorismate_bind pfam00425
chorismate binding enzyme; This family includes the catalytic regions of the chorismate ...
 134-388 1.17e-91

chorismate binding enzyme; This family includes the catalytic regions of the chorismate binding enzymes anthranilate synthase, isochorismate synthase, aminodeoxychorismate synthase and para-aminobenzoate synthase.


Pssm-ID: 425674 [Multi-domain]  Cd Length: 255  Bit Score: 276.36  E-value: 1.17e-91
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053 134 ADYRDAVAAAVDRINAGELSKVVLARTLELTGPQDADLPAMLGRLARRDPGGYTFAVpSGPRTTLVGASPELLVARSGGV 213
Cdd:pfam00425   1 EDYLAAVEKAKEAIRAGDLYKVVLSRRLTLPLAGDIDPLALYRRLRARNPAPYSFYF-RTGDFTFLGASPERLLSVDGGR 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053 214 LVANPLAGSTPRSADLAEDVRRAAALLESAKDIHEHAVVVDAVRAALAPFC--TELDVPERPTLVRTATMWHLSTTVTGR 291
Cdd:pfam00425  80 IITEPIAGTRPRGKDPAEDEALAAELLADPKERAEHLMVVDLIRNDLGRVCvpGSVKVPELPEVERYGTVQHLVSTISGR 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053 292 IAdPGTTALDLASALHPTPAVCGTPDDTARRVIADSEPFDRGLYTGMVGWQDADGDGEWVVTLRCAEAEGATLRLFAGAG 371
Cdd:pfam00425 160 LK-PGLSLLDLLKALFPTGAVTGAPKKRAMEIIRELEPFPRGLYAGAVGYLDPDGDADFAVAIRTALVDNGRARLYAGAG 238

                         250
                  ....*....|....*..
gi 2543669053 372 VVGDSSPQAETDETGAK 388
Cdd:pfam00425 239 IVADSDPEAEWEETEAK 255
isochor_syn TIGR00543
isochorismate synthases; This enzyme interconverts chorismate and isochorismate. In E. coli, ...
 78-395 5.28e-90

isochorismate synthases; This enzyme interconverts chorismate and isochorismate. In E. coli, different loci encode isochorismate synthases for the pathways of menaquinone biosynthesis and enterobactin biosynthesis (via salicilate) and fail to complement each other. Among isochorismate synthases, the N-terminal domain is poorly conserved. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 273127  Cd Length: 351  Bit Score: 275.40  E-value: 5.28e-90
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053  78 PIVVGALPFDPSGRPA--------LVVPE--------------TVRRAPALREDPLIAL----------PAPEPSDGGGW 125
Cdd:TIGR00543   1 PRLFGGFPFDPEEPAAweefgegyFVLPEvlvesdgggtlltcTIVAEPELNEADLLLYakfavssgirPLRALPEQMTT 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053 126 HVR-EVPAAADYRDAVAAAVDRINAGELSKVVLARTLELTGPQDADLPAMLGRLARRDPGGYTFAVPSGPRTTLVGASPE 204
Cdd:TIGR00543  81 LTTgEDPDKAAWRTAVEEALENIRQGPLDKVVLARALTLKFADDIDPIAVLANLRQQYPNAYIFLLEPPQGGVFLGATPE 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053 205 LLVARSGGVLVANPLAGSTPRSADLAEDVRRAAALLESAKDIHEHAVVVDAVRAALAPFCTELDVPERPTLVRTATMWHL 284
Cdd:TIGR00543 161 RLLSREKGELLTEALAGTAPRSADPEEDRKLGELLLKDDKNLREHRLVVEYIRRRLQPICTSLDVSETPELLKLANVQHL 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053 285 STTVTGRIAdPGTTALDLASALHPTPAVCGTPDDTARRVIADSEPFDRGLYTGMVGWQDADGDGEWVVTLRCAEAEGATL 364
Cdd:TIGR00543 241 YTPISARLK-DGDSLLDLLKQLHPTPAVGGLPREEALDFIREHEPFDRGLYAAPLGWLDGEGNGEFAVGIRSALVEDGQV 319

                         330       340       350
                  ....*....|....*....|....*....|.
gi 2543669053 365 RLFAGAGVVGDSSPQAETDETGAKFRTFLNA 395
Cdd:TIGR00543 320 RLYAGAGIVADSDPESEWEETELKLQTMLRA 350
 
Name Accession Description Interval E-value
PRK06923 PRK06923
isochorismate synthase DhbC; Validated
 21-397 1.15e-160

isochorismate synthase DhbC; Validated


Pssm-ID: 235886 [Multi-domain]  Cd Length: 399  Bit Score: 457.27  E-value: 1.15e-160
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053  21 ATALLDAYRPGTDRFLATPRLTLLCTGAAAELAEDD-RPVTERVQELLDARRLAGDPEPIVVGALPFDPSGRPALVVPET 99
Cdd:PRK06923   11 SEKLLEDYKTESSFFFASPTRTILAEGEFTTVKHHEiESFPERVQAVLRNAKQAGNPNPIVVGALPFDRRKEVQLIVPEY 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053 100 VRRAPALREDPLIALpapEPSDGGGWHVREVPAAADYRDAVAAAVDRINAGELSKVVLARTLELTGPQDADLPAMLGRLA 179
Cdd:PRK06923   91 SRISERLQLDTTNHL---EINRNLTFEMTPVPDPEVYMNGVKQGIAKIQDGDLKKIVLSRSLDVKSSEKIDKQKLLRELA 167

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053 180 RRDPGGYTFAV--PSG---PRTTLVGASPELLVARSGGVLVANPLAGSTPRSADLAEDVRRAAALLESAKDIHEHAVVVD 254
Cdd:PRK06923  168 EHNKHGYTFAVnlPKDeneNSKTLIGASPELLVSRHGMQVISNPLAGSRPRSDDPVEDKRRAEELLSSPKDLHEHAVVVE 247

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053 255 AVRAALAPFCTELDVPERPTLVRTATMWHLSTTVTGRIADPGTTALDLASALHPTPAVCGTPDDTARRVIADSEPFDRGL 334
Cdd:PRK06923  248 AVAAALRPYCHTLHVPEKPSVIHTEAMWHLSTEVKGELKDPNTSSLELAIALHPTPAVCGTPTEEAREAIQQIEPFDREF 327

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2543669053 335 YTGMVGWQDADGDGEWVVTLRCAEAEGATLRLFAGAGVVGDSSPQAETDETGAKFRTFLNAVG 397
Cdd:PRK06923  328 FTGMLGWSDLNGDGEWIVTIRCAEVEENTLRLYAGAGVVAESKPEDELAETSAKFQTMLKAMG 390
MenF COG1169
Isochorismate synthase EntC [Coenzyme transport and metabolism, Secondary metabolites ...
 40-397 6.40e-137

Isochorismate synthase EntC [Coenzyme transport and metabolism, Secondary metabolites biosynthesis, transport and catabolism]; Isochorismate synthase EntC is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440783 [Multi-domain]  Cd Length: 353  Bit Score: 395.29  E-value: 6.40e-137
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053  40 RLTLLCTGAAAEL----AEDDRPVTERVQELLDARRLAGdPEPIVVGALPFDP---SGRPALVVPETVRRapalredpli 112
Cdd:COG1169    11 GEGLAGLGEAARFeapgPDRFAALAAAWQALLADAALAG-TGPRAFGGFAFDPdspAPAARLVLPRLLLR---------- 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053 113 alpapepsdgggWHVREVPAAADYRDAVAAAVDRINAGELSKVVLARTLELTGPQDADLPAMLGRLARRDPGGYTFAVPS 192
Cdd:COG1169    80 ------------RSRRGVPDPAEWREAVAQALEAIRAGELDKVVLARALDLTLDEPIDPRALLARLRRRNPDCYTFAVEL 147

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053 193 GPRTTLVGASPELLVARSGGVLVANPLAGSTPRSADLAEDVRRAAALLESAKDIHEHAVVVDAVRAALAPFCTELDVPER 272
Cdd:COG1169   148 GAGDGFVGASPERLVRRRGGQLTTEALAGTAPRGADPEEDAALAAALLASEKDRREHALVVDSIREALAPLCSSLDVPEE 227

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053 273 PTLVRTATMWHLSTTVTGRIaDPGTTALDLASALHPTPAVCGTPDDTARRVIADSEPFDRGLYTGMVGWQDADGDGEWVV 352
Cdd:COG1169   228 PELLRLRNVQHLATPITGTL-DPGVSALDLAAALHPTPAVGGTPREAALALIRELEPFDRGWYAGPVGWVDADGDGEFAV 306

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*
gi 2543669053 353 TLRCAEAEGATLRLFAGAGVVGDSSPQAETDETGAKFRTFLNAVG 397
Cdd:COG1169   307 AIRSALIDGNRARLFAGAGIVAGSDPEAEWAETEAKLRTMLRALG 351
Chorismate_bind pfam00425
chorismate binding enzyme; This family includes the catalytic regions of the chorismate ...
 134-388 1.17e-91

chorismate binding enzyme; This family includes the catalytic regions of the chorismate binding enzymes anthranilate synthase, isochorismate synthase, aminodeoxychorismate synthase and para-aminobenzoate synthase.


Pssm-ID: 425674 [Multi-domain]  Cd Length: 255  Bit Score: 276.36  E-value: 1.17e-91
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053 134 ADYRDAVAAAVDRINAGELSKVVLARTLELTGPQDADLPAMLGRLARRDPGGYTFAVpSGPRTTLVGASPELLVARSGGV 213
Cdd:pfam00425   1 EDYLAAVEKAKEAIRAGDLYKVVLSRRLTLPLAGDIDPLALYRRLRARNPAPYSFYF-RTGDFTFLGASPERLLSVDGGR 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053 214 LVANPLAGSTPRSADLAEDVRRAAALLESAKDIHEHAVVVDAVRAALAPFC--TELDVPERPTLVRTATMWHLSTTVTGR 291
Cdd:pfam00425  80 IITEPIAGTRPRGKDPAEDEALAAELLADPKERAEHLMVVDLIRNDLGRVCvpGSVKVPELPEVERYGTVQHLVSTISGR 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053 292 IAdPGTTALDLASALHPTPAVCGTPDDTARRVIADSEPFDRGLYTGMVGWQDADGDGEWVVTLRCAEAEGATLRLFAGAG 371
Cdd:pfam00425 160 LK-PGLSLLDLLKALFPTGAVTGAPKKRAMEIIRELEPFPRGLYAGAVGYLDPDGDADFAVAIRTALVDNGRARLYAGAG 238

                         250
                  ....*....|....*..
gi 2543669053 372 VVGDSSPQAETDETGAK 388
Cdd:pfam00425 239 IVADSDPEAEWEETEAK 255
isochor_syn TIGR00543
isochorismate synthases; This enzyme interconverts chorismate and isochorismate. In E. coli, ...
 78-395 5.28e-90

isochorismate synthases; This enzyme interconverts chorismate and isochorismate. In E. coli, different loci encode isochorismate synthases for the pathways of menaquinone biosynthesis and enterobactin biosynthesis (via salicilate) and fail to complement each other. Among isochorismate synthases, the N-terminal domain is poorly conserved. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 273127  Cd Length: 351  Bit Score: 275.40  E-value: 5.28e-90
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053  78 PIVVGALPFDPSGRPA--------LVVPE--------------TVRRAPALREDPLIAL----------PAPEPSDGGGW 125
Cdd:TIGR00543   1 PRLFGGFPFDPEEPAAweefgegyFVLPEvlvesdgggtlltcTIVAEPELNEADLLLYakfavssgirPLRALPEQMTT 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053 126 HVR-EVPAAADYRDAVAAAVDRINAGELSKVVLARTLELTGPQDADLPAMLGRLARRDPGGYTFAVPSGPRTTLVGASPE 204
Cdd:TIGR00543  81 LTTgEDPDKAAWRTAVEEALENIRQGPLDKVVLARALTLKFADDIDPIAVLANLRQQYPNAYIFLLEPPQGGVFLGATPE 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053 205 LLVARSGGVLVANPLAGSTPRSADLAEDVRRAAALLESAKDIHEHAVVVDAVRAALAPFCTELDVPERPTLVRTATMWHL 284
Cdd:TIGR00543 161 RLLSREKGELLTEALAGTAPRSADPEEDRKLGELLLKDDKNLREHRLVVEYIRRRLQPICTSLDVSETPELLKLANVQHL 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053 285 STTVTGRIAdPGTTALDLASALHPTPAVCGTPDDTARRVIADSEPFDRGLYTGMVGWQDADGDGEWVVTLRCAEAEGATL 364
Cdd:TIGR00543 241 YTPISARLK-DGDSLLDLLKQLHPTPAVGGLPREEALDFIREHEPFDRGLYAAPLGWLDGEGNGEFAVGIRSALVEDGQV 319

                         330       340       350
                  ....*....|....*....|....*....|.
gi 2543669053 365 RLFAGAGVVGDSSPQAETDETGAKFRTFLNA 395
Cdd:TIGR00543 320 RLYAGAGIVADSDPESEWEETELKLQTMLRA 350
PRK15016 PRK15016
isochorismate synthase EntC; Provisional
 35-397 1.48e-78

isochorismate synthase EntC; Provisional


Pssm-ID: 184977 [Multi-domain]  Cd Length: 391  Bit Score: 247.48  E-value: 1.48e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053  35 FLATPRLTLLCTGAAAELAED-------DRPVTERVQELLDARRLAGDPEPIVVGALPFDPSGRPALVVPET-------V 100
Cdd:PRK15016   22 FFMSPYRSFTTSGCFARFDEPavngdspDSPFQQKLAALFADAKAQGIKNPVMVGAIPFDTRQPSSLYIPESwqsfsrqE 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053 101 RRAPALREDPLIALPAPEPsdgggwhvREVPAAADYRDAVAAAVDRINAGELSKVVLARTLELTGPQDADLPAMLGRLAR 180
Cdd:PRK15016  102 KQRSARRFTRSQSLNVVER--------QAIPEQTTFEAMVARAAALTATPQVDKVVLSRLIDITTDAAIDSGALLERLIA 173

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053 181 RDPGGYTFAVPSGPRTTLVGASPELLVARSGGVLVANPLAGSTPRSADLAEDVRRAAALLESAKDIHEHAVVVDAVRAAL 260
Cdd:PRK15016  174 QNPVSYNFHVPLADGGVLLGASPELLLRKDGERFSSLPLAGSARRQPDEVLDREAGNRLLASEKDRHEHELVTQAMKEVL 253

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053 261 APFCTELDVPERPTLVRTATMWHLSTTVTGRiADPGTTALDLASALHPTPAVCGTPDDTARRVIADSEPFDRGLYTGMVG 340
Cdd:PRK15016  254 RERSSELHVPSSPQLITTPTLWHLATPFEGK-ANAQENALTLACLLHPTPALSGFPHQAAKQVIAELEPFDRELFGGIVG 332

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2543669053 341 WQDADGDGEWVVTLRCAEAEGATLRLFAGAGVVGDSSPQAETDETGAKFRTFLNAVG 397
Cdd:PRK15016  333 WCDSEGNGEWVVTIRCAKLRENQVRLFAGAGIVPASSPLGEWRETGVKLSTMLNVFG 389
PRK07054 PRK07054
isochorismate synthase;
41-398 1.23e-59

isochorismate synthase;


Pssm-ID: 235920 [Multi-domain]  Cd Length: 475  Bit Score: 200.76  E-value: 1.23e-59
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053  41 LTLLCTGAAAELAE--DDR--PVTERVQELLDARRLAGDPEPIVVGALPFDPSG----------RPALVVP--ETVRRAP 104
Cdd:PRK07054   63 VALFGWGCALELNAhgDQRfaRLEARWRALVADAVVAGPQPPRLVGGFRFDPRGprsahwqafaDASLTLAklLVVREGE 142

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053 105 ALR----------EDP------------LIALPAPEPSDGGGWHVREVPAAAD-YRDAVAAAVDRINAGELSKVVLARTL 161
Cdd:PRK07054  143 AYWavcqhlvaahDDPaalagaccarieRLARPAPAADDDAPRLLRASALQAReWQHEVRRAVDAIRGGAFGKVVLARDV 222

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053 162 ELTGPQDADLPAMLGRLARRDPGGYTFAVPSGpRTTLVGASPELLVARSGGVLVANPLAGSTPRSADLAEDVRRAAALLE 241
Cdd:PRK07054  223 LQQYARPVAIGPLLRRLRLRDPHAHLFAFRRG-NACFLGATPERLVRVAAGDLHTHALAGTIARGADPAEDARLGAALMA 301

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053 242 SAKDIHEHAVVVDAVRAALAPFCTELDVPERPTLVRTATMWHLSTTVTGRIAdPGTTALDLASALHPTPAVCGTPDDTAR 321
Cdd:PRK07054  302 SAKDRLEHALVVDAIRAALAPLSRALDIPDQPSLHRLPRLQHLSTPIRATLA-PDATLLQVVAALHPTPAVGGHPRAAAL 380

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2543669053 322 RVIADSEPFDRGLYTGMVGWQDADGDGEWVVTLRCAEAEGATLRLFAGAGVVGDSSPQAETDETGAKFRTFLNAVGA 398
Cdd:PRK07054  381 DYIRAHEGFDRGWYAAPIGWLDAHGNGDFAVALRSALITGGACRLFAGCGIVADSEPASEYRETCLKLSGMREALRA 457
TrpE COG0147
Anthranilate/para-aminobenzoate synthases component I [Amino acid transport and metabolism, ...
 134-398 2.11e-42

Anthranilate/para-aminobenzoate synthases component I [Amino acid transport and metabolism, Coenzyme transport and metabolism]; Anthranilate/para-aminobenzoate synthases component I is part of the Pathway/BioSystem: Aromatic amino acid biosynthesis


Pssm-ID: 439917 [Multi-domain]  Cd Length: 416  Bit Score: 153.33  E-value: 2.11e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053 134 ADYRDAVAAAVDRINAGELSKVVLARTLELtgPQDADLPAMLGRLARRDPGGYTFAVPSGPRTtLVGASPELLVARSGGV 213
Cdd:COG0147   154 EEYLAAVERAKEYIRAGDIFQVVLSQRFSA--PFEGDPLALYRALRRINPSPYMFYLRFGDFA-IVGSSPERLVRVEDGR 230

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053 214 LVANPLAGSTPRSADLAEDVRRAAALLESAKDIHEHavvvdavraalapfcteL-------------------DVPERPT 274
Cdd:COG0147   231 VETRPIAGTRPRGATPEEDAALAEELLADEKERAEH-----------------LmlvdlarndlgrvcepgsvKVPELMV 293

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053 275 LVRTATMWHLSTTVTGRIAdPGTTALDLASALHPTPAVCGTPDDTARRVIADSEPFDRGLYTGMVGWQDADGDGEWVVTL 354
Cdd:COG0147   294 VERYSHVMHLVSTVTGRLR-PGLDALDALRATFPAGTLTGAPKIRAMEIIDELEPTRRGVYGGAVGYLSFDGNMDLAIAI 372

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....
gi 2543669053 355 RCAEAEGATLRLFAGAGVVGDSSPQAETDETGAKFRTFLNAVGA 398
Cdd:COG0147   373 RTAVVKDGRAYVQAGAGIVADSDPEAEYQETLNKARALLRALEL 416
PLN02786 PLN02786
isochorismate synthase
 130-384 6.77e-39

isochorismate synthase


Pssm-ID: 178383 [Multi-domain]  Cd Length: 533  Bit Score: 146.08  E-value: 6.77e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053 130 VPAAADYRDAVAAAVDRINAGE--LSKVVLARTLELTGPQDADLPAMLGRLARRDPGGYTFAV--PSGPrtTLVGASPEL 205
Cdd:PLN02786  256 VPSKGAWHLAVNKALQIIKRKSspLKKVVLARSSRIITDTDIDPIAWLACLQVEGQNAYQFCLqpPDAP--AFIGNTPEQ 333

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053 206 LVARSGGVLVANPLAGSTPRSADLAEDVRRAAALLESAKDIHEHAVVVDAVRAALAPFCTELDVPERPTLVRTATMWHLS 285
Cdd:PLN02786  334 LFHRKGLGVCSEALAATRPRGGSSARDLQIELDLLTSPKDDLEFSIVRENIREKLEAICDRVVVEPHKAIRKLARVQHLY 413

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053 286 TTVTGRIADPgTTALDLASALHPTPAVCGTPDDTARRVIADSEPFDRGLYTGMVGWQdADGDGEWVVTLRCAEAE-GATL 364
Cdd:PLN02786  414 AQLAGRLRSE-DDEFDILAALHPTPAVCGHPTEEARLLIAETESFDRGMYAGPVGWF-GGGESEFAVGIRSALVEkGLGA 491

                         250       260
                  ....*....|....*....|
gi 2543669053 365 RLFAGAGVVGDSSPQAETDE 384
Cdd:PLN02786  492 LIYAGTGIVEGSNPSSEWNE 511
PRK09070 PRK09070
aminodeoxychorismate synthase component I;
72-399 4.15e-33

aminodeoxychorismate synthase component I;


Pssm-ID: 236371 [Multi-domain]  Cd Length: 447  Bit Score: 128.67  E-value: 4.15e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053  72 LAGDPEPIVvgALPFDPSGRP---------ALVVPETVRRAPALRE-----------DPLIALPAPEPsdGGGW----HV 127
Cdd:PRK09070  102 LAGQVEPIL--KLPMRTDGLPlalalrapaAVLRDRHSGRCVLVAEpgrehlldqieADLAACAALPP--LPVWlapqAV 177

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053 128 REVPAAAdYRDAVAAAVDRINAGELSKVVLARTLELTGPQDADLPAMLGRLARRDPGGYTFAVPSGPRTtLVGASPELLV 207
Cdd:PRK09070  178 EEDPPER-FTDGVERVLDYIRAGDVFQVNLSRAWQAQFANAVDPAALYARLRAANPAPFSGLFVAAGRA-IVSSSPERLV 255

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053 208 ARSGGVLVANPLAGSTPRSADlAEDVRRAAALLESAKDIHEHAVVVDAVRAALAPFCT--ELDVPERPTLVRTATMWHLS 285
Cdd:PRK09070  256 SVQGGVVQTRPIAGTRPRFAG-DDDAALIRELVGHPKERAEHVMLIDLERNDLGRICApgSVEVDELMTVESYAHVHHIV 334

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053 286 TTVTGRIADpGTTALDLASALHPTPAVCGTPDDTARRVIADSEPFDRGLYTGMVGWQDADGDGEWVVTLRCAEAEGATLR 365
Cdd:PRK09070  335 SNVRGRLRD-GVTPGEVIRAVFPGGTITGCPKVRCMQIIAELEQTPRGAYTGSFGYLNRDGDMDLNILIRTAEVQGNQVR 413

                         330       340       350
                  ....*....|....*....|....*....|....
gi 2543669053 366 LFAGAGVVGDSSPQAETDETGAKFRTFLNAVGAT 399
Cdd:PRK09070  414 FRTGAGIVVDSDPERELDETRAKARGLLRALEQA 447
PRK13571 PRK13571
anthranilate synthase component I; Provisional
 132-398 3.48e-30

anthranilate synthase component I; Provisional


Pssm-ID: 184152 [Multi-domain]  Cd Length: 506  Bit Score: 121.28  E-value: 3.48e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053 132 AAADYRDAVAAAVDRINAGELSKVVLARTLELTGPQDA-DLPAMLgRLARRDPGGYTFAVPSGPRTT---LVGASPELLV 207
Cdd:PRK13571  228 TVEEFGAAVEKLVEEIRAGEAFQVVPSQRFEMDTTADPlDVYRVL-RVTNPSPYMYLLRVPNSDGGTdfsIVGSSPEALV 306

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053 208 ARSGGVLVANPLAGSTPRSADLAEDVRRAAALLESAKDIHEHAVVVDAVRAALAPFCT--ELDVPERPTLVRTATMWHLS 285
Cdd:PRK13571  307 TVTDGRATTHPIAGTRWRGATPEEDALLEKELLADPKERAEHLMLVDLGRNDLGRVCRpgTVRVVDFSHIERYSHVMHLV 386

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053 286 TTVTGRIAdPGTTALDLASALHPTPAVCGTPDDTARRVIADSEPFDRGLYTGMVGWQDADGDGEWVVTLRCAEAEGATLR 365
Cdd:PRK13571  387 STVTGELA-EGRTALDAVTACFPAGTLSGAPKVRAMELIEELEPTRRGLYGGVVGYLDFAGDADTAIAIRTALMRDGTAY 465

                         250       260       270
                  ....*....|....*....|....*....|...
gi 2543669053 366 LFAGAGVVGDSSPQAETDETGAKFRTFLNAVGA 398
Cdd:PRK13571  466 VQAGGGVVADSDPDYEDNEARNKAAAVLRAIAA 498
PRK07508 PRK07508
aminodeoxychorismate synthase component I;
97-384 2.87e-28

aminodeoxychorismate synthase component I;


Pssm-ID: 236035 [Multi-domain]  Cd Length: 378  Bit Score: 114.34  E-value: 2.87e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053  97 PETVRRAPALREDPLIALPAPE-PSDGGGWHVREVPAAA------------DYRDAVAAAVDRINAGELSKVVLarTLEL 163
Cdd:PRK07508   62 PKLAPLMPEGRETPLLCFGVFDaPSPEAPAPARPSENAArlrdpvarwdfaDYAQRFERLHRHIRAGDCYQANL--TFPL 139

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053 164 TGPQDADLPAMLGRLARRDPGGY-TFAVPSGPrtTLVGASPELLVARSG-GVLVANPLAGSTPRSADLAEDVRRAAALLE 241
Cdd:PRK07508  140 DARWGGDPLALFWALAARQPVGYgALVDLGGP--VILSRSPELFFRVDGeGWIETHPMKGTAPRGATPAEDARLRAALLN 217

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053 242 SAKDIHEHAVVVDAVRAALAPFCT--ELDVPERPTLVRTATMWHLSTTVTGRIAdPGTTALDLASALHPTPAVCGTPDDT 319
Cdd:PRK07508  218 DEKNQAENRMIVDLLRNDISRISEvgSLDVPELFDIETYPTVHQMVSRVRARLL-PGLGLADIFAALFPCGSITGAPKIR 296

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2543669053 320 ARRVIADSEPFDRGLYTGMVGWQDADGDGEWVVTLRcaeaegaTLRLFA--------GAGVVGDSSPQAETDE 384
Cdd:PRK07508  297 AMEILRELEPGPRDLYCGAIGWIAPDGRMRFNVAIR-------TLSLFPggravfnvGGGIVFDSTAEAEYEE 362
PRK13572 PRK13572
anthranilate synthase component I; Provisional
 135-397 4.93e-25

anthranilate synthase component I; Provisional


Pssm-ID: 237432 [Multi-domain]  Cd Length: 435  Bit Score: 105.97  E-value: 4.93e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053 135 DYRDAVAAAVDRINAGELSKVVLARTLELtgpqDADLPA--MLGRLARRDPGGYTFAVPSGprTTLVGASPELLVARSGG 212
Cdd:PRK13572  174 EFVEMVEKAKEYIYSGDVFQVVLSREYRL----KTDLSPfqLYRNLREINPSPYMFLLEFD--KDVVGASPETMASVENN 247

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053 213 VLVANPLAGSTPRSADLAEDVRRAAALLESAKDIHEHAVVVDAVRAALAPFCTELDVP-ER-PTLVRTATMWHLSTTVTG 290
Cdd:PRK13572  248 ILKINPIAGTAPRGKTEEEDKKLAEALLSDEKERAEHVMLVDLARNDVRKVSKSGSVRlERfFDVVKYSHVQHIESEVVG 327

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053 291 RIADpGTTALDLASALHPTPAVCGTPDDTARRVIADSEPFDRGLYTGMVGWQDADGDGEWVVTLRCAEAEGaTLRLFAGA 370
Cdd:PRK13572  328 ELKE-DSTMFDAIEAAFPAGTLTGAPKFRAMEIIDELEKSRRKVYGGAVGYFSNSGNADLAIAIRMAEIDK-VCRVRAGA 405

                         250       260
                  ....*....|....*....|....*..
gi 2543669053 371 GVVGDSSPQAETDETGAKFRTFLNAVG 397
Cdd:PRK13572  406 GIVADSVPEKEFYETERKMAAVLKALG 432
PRK15012 PRK15012
menaquinone-specific isochorismate synthase; Provisional
 128-393 1.12e-24

menaquinone-specific isochorismate synthase; Provisional


Pssm-ID: 184974 [Multi-domain]  Cd Length: 431  Bit Score: 104.93  E-value: 1.12e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053 128 REVPAAADYRDAVAAAVDRINAGELSKVVLARTLELTGPQDADLPAMLGRLARRDPGGYTFAVPSGPRTTLVGASPELLV 207
Cdd:PRK15012  164 QHWPDKTGWTQLIELATKTIAEGELDKVVLARATDLHFASPVNAAAMMAASRRLNLNCYHFYMAFDAENAFLGSSPERLW 243

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053 208 ARSGGVLVANPLAGSTPRSADLAEDVRRAAALLESAKDIHEHAVVVDAVRAALAPFCTELDV-PerPTLVRTATMWHLST 286
Cdd:PRK15012  244 RRRDKALRTEALAGTVANHPDDKQAQQLGEWLMADDKNQRENMLVVEDICQRLQADTQTLDVlP--PQVLRLRKVQHLRR 321

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053 287 TVtgriadpgTTALDLAS------ALHPTPAVCGTPDDTARRVIADSEPFDRGLYTGMVGWQDADgDGEWVVTLRCAEAE 360
Cdd:PRK15012  322 CI--------WTSLNKADdviclhQLQPTAAVAGLPRDLARQFIARHEPFTREWYAGSAGYLSLQ-QSEFCVSLRSAKVS 392

                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 2543669053 361 GATLRLFAGAGVVGDSSPQ---AETDETGAKFRTFL 393
Cdd:PRK15012  393 GNVVRLYAGAGIVRGSDPEqewQEIDNKAAGLRTLL 428
PRK05877 PRK05877
aminodeoxychorismate synthase component I; Provisional
 113-384 7.61e-23

aminodeoxychorismate synthase component I; Provisional


Pssm-ID: 235634 [Multi-domain]  Cd Length: 405  Bit Score: 99.39  E-value: 7.61e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053 113 ALPAPEPSDGGGWHVR-EVPAAADYRDAVAAAVDRINAGELSKV-VLARtleLTGPQDADLPAMLGRLARRDPGGYTfAV 190
Cdd:PRK05877  120 ALATTRARPAPPCRIDwTPPDRAAHRDGVLACLEAIAAGEVYQAcVCTQ---FTGTVTGSPLDFFADGVARTAPARA-AY 195

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053 191 PSGPRTTLVGASPELLVARSGGVLVANPLAGSTPRSADlaedvrrAAALLESAKDIHEHAVVVDAVRAALAPFCTELDV- 269
Cdd:PRK05877  196 LAGDWGAVASLSPELFLRRRGSVVTSSPIKGTLPLDAD-------PSALRASAKDVAENIMIVDLVRNDLGRVARTGTVt 268

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053 270 -PERPTLVRTATMWHLSTTVTGRIaDPGTTALDLASALHPTPAVCGTPDDTARRVIADSEPFDRGLYTGMVGWQDADGDG 348
Cdd:PRK05877  269 vPELLVVRPAPGVWHLVSTVSAQV-PDELPMSDLLDATFPPASVTGTPKLRARELISQWEPVRRGIYCGTVGLASPVAGC 347

                         250       260       270
                  ....*....|....*....|....*....|....*..
gi 2543669053 349 EWVVTLRCAE-AEGATLRLFAGAGVVGDSSPQAETDE 384
Cdd:PRK05877  348 ELNVAIRTVEfDADGNAVLGVGGGITADSDPDAEWQE 384
PRK06404 PRK06404
anthranilate synthase component I; Reviewed
 140-393 9.16e-23

anthranilate synthase component I; Reviewed


Pssm-ID: 102361 [Multi-domain]  Cd Length: 351  Bit Score: 98.40  E-value: 9.16e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053 140 VAAAVDRINAGELSKVVLARTLEltgpQDADLPAMLGRLARRDPGGYTFAVPSGpRTTLVGASPELLVARSGGVLVANPL 219
Cdd:PRK06404  111 IKELIELIRAGEVLQVVISREFE----ANIDFKEKLSEFINNDRSRYVFYYRFG-KYRVVGSSPENVFTVNGNIINVDPI 185

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053 220 AGSTPRSAdlaedvrRAAALLESAKDIHEHAVVVDAVRAALAPFCT--ELDVPERPTLVRTATMWHLSTTVTGRIADpgT 297
Cdd:PRK06404  186 AGTYDDKI-------LSNELLNSEKDKLEHRMLLDLARNDLSKFADigTLNVDKVMKIEEFSSVKHLVSQVTAKFSN--A 256

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053 298 TALDLASALHPTPAVCGTPDDTARRVIADSEPFDRGLYTGMVGWQdADGDGEWVVTLRCAEAEGATLRLFAGAGVVGDSS 377
Cdd:PRK06404  257 SYRDILASMFPAGTVSGSPKERAIEIINKYEETPRGPYGGAIGII-SKGYTDMALVIRTAYSHGNGFRVRAGAGIVKDSD 335

                         250
                  ....*....|....*.
gi 2543669053 378 PQAETDETGAKFRTFL 393
Cdd:PRK06404  336 PEDEVNEIYSKARSVM 351
PRK07912 PRK07912
salicylate synthase;
104-391 1.38e-21

salicylate synthase;


Pssm-ID: 169151 [Multi-domain]  Cd Length: 449  Bit Score: 96.01  E-value: 1.38e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053 104 PALRED--PLIALPAPEPSDGGGWHVREVPAaaDYRDAVAAAVDRINAGELSKVVLARTLELtgPQDADLPAMLGRLARR 181
Cdd:PRK07912  154 IRHREAidRLLATGVREVPQSRSVDVSDDPS--GYRDRVAVAVAEIAAGRYHKVILSRCVEV--PFAVDFPATYRLGRRH 229

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053 182 DPGGYTFAVPSGPRTTLvGASPELLVA-RSGGVLVANPLAGStpRSADLAEDVRRAA-ALLES-AKDIHEHAVVVDAVRA 258
Cdd:PRK07912  230 NTPVRSFLLRLGGIRAL-GYSPELVTAvRADGVVITEPLAGT--RAFGRGAAIDRLArDDLESnSKEIVEHAISVRSSLA 306

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053 259 ALapfcTELDVPERP------TLVRTATMWHLSTTVTGRIaDPGTTALDLASALHPTPAVCGTPDDTARRVIADSEPFDR 332
Cdd:PRK07912  307 EI----TEIAEPGSAavidfmTVRERGSVQHLGSTVRGRL-DASSDRMDALEALFPAVTASGIPKAAGVDAIFRLDEAPR 381

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2543669053 333 GLYTGMVGWQDADGDGEWVVTLRCAEAEGATLRLFAGAGVVGDSSPQAETDETGAKFRT 391
Cdd:PRK07912  382 GLYSGAVVMLSADGGLDAALTLRAAYQVGGRTWLRAGAGIIEESEPEREFEETCEKLST 440
PRK06772 PRK06772
salicylate synthase;
123-389 3.00e-18

salicylate synthase;


Pssm-ID: 102546 [Multi-domain]  Cd Length: 434  Bit Score: 85.94  E-value: 3.00e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053 123 GGWHVREVPAAAD-------YRDAVAAAVDRINAGELSKVVLARTLELtgPQDADLPAML--GRLARRDPGGYTFAVPSg 193
Cdd:PRK06772  155 AGTTTQNAPLAVDtalngeaYKQQVARAVAEIRRGEYVKVIVSRAIPL--PSRIDMPATLlyGRQANTPVRSFMFRQEG- 231

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053 194 pRTTLvGASPELLVARSGGVLVANPLAGSTPRSADLAEDVRRAAALLESAKDIHEHAVVVDAVRAALAPFCT--ELDVPE 271
Cdd:PRK06772  232 -REAL-GFSPELVMSVTGNKVVTEPLAGTRDRMGNPEHNKAKEAELLHDSKEVLEHILSVKEAIAELEAVCQpgSVVVED 309

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053 272 RPTLVRTATMWHLSTTVTGRIADpGTTALDLASALHPTPAVCGTPDDTARRVIADSEPFDRGLYTGMVGWQDaDGDGEWV 351
Cdd:PRK06772  310 LMSVRQRGSVQHLGSGVSGQLAE-NKDAWDAFTVLFPSITASGIPKNAALNAIMQIEKTPRELYSGAILLLD-DTRFDAA 387

                         250       260       270
                  ....*....|....*....|....*....|....*...
gi 2543669053 352 VTLRCAEAEGATLRLFAGAGVVGDSSPQAETDETGAKF 389
Cdd:PRK06772  388 LVLRSVFQDSQRCWIQAGAGIIAQSTPERELTETREKL 425
PRK13567 PRK13567
anthranilate synthase component I; Provisional
 178-393 1.43e-17

anthranilate synthase component I; Provisional


Pssm-ID: 184148 [Multi-domain]  Cd Length: 468  Bit Score: 84.04  E-value: 1.43e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053 178 LARRDPGGYTFAVPSGPRTtLVGASPELLVARSGGVLVANPLAGSTPRSADLAEDVRRAAALLESAKDIHEHAVVVD--- 254
Cdd:PRK13567  249 LKRQNPSPYMYYLNIDQPY-IVGSSPESFVSVKDQIVTTNPIAGTIQRGETTQIDNENMKQLLNDPKECSEHRMLVDlgr 327

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053 255 ----AVRAALAPFCTELDVPERPTLVRtatmwHLSTTVTGRIaDPGTTALDLASALHPTPAVCGTPDDTARRVIADSEPF 330
Cdd:PRK13567  328 ndihRVSKIGTSKITKLMVIEKYEHVM-----HIVSEVTGKI-NQNLSPMTVIANLLPTGTVSGAPKLRAIERIYEQYPH 401

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2543669053 331 DRGLYTGMVGWQDADGDGEWVVTLRCAEAEGATLRLFAGAGVVGDSSPQAETDETGAKFRTFL 393
Cdd:PRK13567  402 KRGVYSGGVGYINCNHNLDFALAIRTMMIDEQYINVEAGCGVVYDSIPEKELNETKLKAKSLL 464
PLN02445 PLN02445
anthranilate synthase component I
 135-388 3.23e-11

anthranilate synthase component I


Pssm-ID: 215244 [Multi-domain]  Cd Length: 523  Bit Score: 64.70  E-value: 3.23e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053 135 DYRDAVAAAVDRINAGELSKVVLARtleltgpqdadlpamlgRLARRdpggyTFAVP-----------SGPRTT------ 197
Cdd:PLN02445  237 EYKNAVLQAKEHILAGDIFQIVLSQ-----------------RFERR-----TFADPfevyralrivnPSPYMIylqarg 294

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053 198 --LVGASPELLVARSGGVLVANPLAGSTPRSADLAEDVRRAAALLESAKDIHEHAvvvdavraalapFCTEL---DVPE- 271
Cdd:PLN02445  295 ciLVASSPEILTRVKKNKIVNRPLAGTRRRGKTPEEDKALEKDLLADEKQCAEHI------------MLVDLgrnDVGKv 362

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053 272 -RPTLV---------RTATMWHLSTTVTGRIADpGTTALDLASALHPTPAVCGTPDDTARRVIADSEPFDRGLYTGMVGW 341
Cdd:PLN02445  363 sKAGSVkveklmnieRYSHVMHISSTVTGELLD-HLTSWDALRAALPVGTVSGAPKVRAMELIDELEVTRRGPYSGGFGG 441

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2543669053 342 QDADGDGEWVVTLRC----AEAEGATL--------------RLFAGAGVVGDSSPQAETDETGAK 388
Cdd:PLN02445  442 VSFTGDMDIALALRTmvfpTAARYDTMysykdtnsrrewvaHLQAGAGIVADSDPEDEYRECVNK 506
pabB PRK15465
aminodeoxychorismate synthase component 1;
202-393 5.05e-11

aminodeoxychorismate synthase component 1;


Pssm-ID: 185362 [Multi-domain]  Cd Length: 453  Bit Score: 64.17  E-value: 5.05e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053 202 SPELLVARSGGVLVANPLAGSTPRSADLAEDVRRAAALLESAKDIHEHAVVVDAVRAALAPFCT--ELDVPERPTLVRTA 279
Cdd:PRK15465  256 SPERFILCDNSEIQTRPIKGTLPRLPDPQEDSKQAEKLANSAKDRAENLMIVDLMRNDIGRVAVagSVKVPELFVVEPFP 335

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053 280 TMWHLSTTVTGRIADpGTTALDLASALHPTPAVCGTPDDTARRVIADSEPFDRGLYTGMVGWQDADGDGEWVVTLRCAEA 359
Cdd:PRK15465  336 AVHHLVSTITARLPE-QLHASDLLRAAFPGGSITGAPKVRAMEIIDELEPQRRNAWCGSIGYLSFCGNMDTSITIRTLTA 414

                         170       180       190
                  ....*....|....*....|....*....|....
gi 2543669053 360 EGATLRLFAGAGVVGDSSPQAETDETGAKFRTFL 393
Cdd:PRK15465  415 INGQIYCSAGGGIVADSQEEAEYQETFDKVNRIL 448
PRK13566 PRK13566
anthranilate synthase component I;
108-398 7.20e-11

anthranilate synthase component I;


Pssm-ID: 237429 [Multi-domain]  Cd Length: 720  Bit Score: 63.78  E-value: 7.20e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053 108 EDPLIALPAPEPSDgggwhvrevPAAADYRDAVAAAVDRINAGELSKVVLARTLelTGPQDADLPAMLGRLARRDPGGYT 187
Cdd:PRK13566  227 SPYKPTTARPGFAD---------HAPGEYAALVEKAKESFRRGDLFEVVPGQTF--YEPCERSPSEIFRRLKEINPSPYG 295

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053 188 FAVPSGPRTTLVGASPELLVaRSGGVLVAN-PLAGSTPRSADLAEDVRRAAALLESAKDIHEhavvvdavraalAPFCTE 266
Cdd:PRK13566  296 FFINLGDGEYLVGASPEMFV-RVEGRRVETcPISGTIKRGADAIGDAEQIRKLLNSKKDESE------------LTMCTD 362

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053 267 LD--------VPERPTLV--RTATMW-HLSTTV---TGRIAdPGTTALD--LASALHPTpaVCGTPDDTARRVIADSEPF 330
Cdd:PRK13566  363 VDrndksrvcEPGSVKVIgrRQIEMYsRLIHTVdhvEGRLR-PGFDALDafLTHAWAVT--VTGAPKLWAMQFIEDHERS 439

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053 331 DRGLYTGMVGWQDADGDGEWVVTLRCAEAEG--ATLRlfAGAGVVGDSSPQAETDETGAKFRTFLNAVGA 398
Cdd:PRK13566  440 PRRWYGGAVGMVGFDGDMNTGLTLRTIRIKDgvAEVR--VGATLLFDSDPEAEEAETELKASALLQALRG 507
PRK13564 PRK13564
anthranilate synthase component 1;
314-399 6.19e-09

anthranilate synthase component 1;


Pssm-ID: 237428 [Multi-domain]  Cd Length: 520  Bit Score: 57.54  E-value: 6.19e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053 314 GTPDDTARRVIADSEPFDRGLYTGMVGWQDADGDGEWVVTLRCAEAEGATLRLFAGAGVVGDSSPQAETDETGAKFRTFL 393
Cdd:PRK13564  428 GAPKVRAMQLIREVEGQRRGSYGGAVGYLTGHGDLDTCIVIRSAFVENGIATVQAGAGVVLDSDPQSEADETRNKAQAVL 507


                  ....*.
gi 2543669053 394 NAVGAT 399
Cdd:PRK13564  508 RAIATA 513
PLN02889 PLN02889
oxo-acid-lyase/anthranilate synthase
 168-396 1.91e-05

oxo-acid-lyase/anthranilate synthase


Pssm-ID: 215481 [Multi-domain]  Cd Length: 918  Bit Score: 46.76  E-value: 1.91e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053 168 DADLPAMLGRLARRDPGGYT-FAVPSGPRTTLVGASPE-LLVARSGGVLVANPLAGSTPRSADLAEDVRRAAALLESAKD 245
Cdd:PLN02889  677 EIDSLGLYLHLREKNPAPYAaWLNFSNENLCICSSSPErFLKLDRNGMLEAKPIKGTIARGSTPEEDEQLKLQLQYSEKD 756

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053 246 IHEHAVVVDAVRAALAPFCT--ELDVPERPTLVRTATMWHLSTTVTGrIADPGTTALDLASALHPTPAVCGTPDDTARRV 323
Cdd:PLN02889  757 QAENLMIVDLLRNDLGRVCEpgSVHVPNLMDVESYTTVHTMVSTIRG-KKRSNMSPVDCVRAAFPGGSMTGAPKLRSMEL 835

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2543669053 324 IADSEPFDRGLYTGMVGWQDADGDGEWVVTLRCAEAEGATLRLFAGAGVVGDSSPQAETDETGAKFRTFLNAV 396
Cdd:PLN02889  836 LDSLESSSRGIYSGSIGFFSYNQTFDLNIVIRTVVIHEGEASIGAGGAIVALSNPEDEYEEMILKTRAPANAV 908
PRK07093 PRK07093
para-aminobenzoate synthase component I; Validated
 301-388 4.57e-03

para-aminobenzoate synthase component I; Validated


Pssm-ID: 235932 [Multi-domain]  Cd Length: 323  Bit Score: 38.70  E-value: 4.57e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2543669053 301 DLASALHPTPAVCGTPDDTARRVIADSEPFDRGLYTGMVGWQdadgDGEWV---VTLRCAEAEGATLRLFAGAGVVGDSS 377
Cdd:PRK07093  231 DILAKLLPAGSITGAPKEKTVEIIEQAEGYERGFYTGVFGYF----DGESLdsaVMIRFIEQENDGLYFKSGGGITIDSD 306

                          90
                  ....*....|.
gi 2543669053 378 PQAETDETGAK 388
Cdd:PRK07093  307 LKDEYNELIQK 317
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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