NCBI Conserved Domain Search

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ...

5-471

4.06e-92

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]

Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 289.80 E-value: 4.06e-92

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   5 LSLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAaRPD---EGEISFDGHPLGVETPAQARELGI 81
Cdd:TIGR02633   2 LEMKGIVKTFGGVKALDGIDLEVRPGECVGLCGENGAGKSTLMKILSGV-YPHgtwDGEIYWSGSPLKASNIRDTERAGI 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  82 AMVHQHFALFDTLSVTENVALG----LSTGISA-AEIEREIRLLGEKYGLEVDPAS-VVMELSMGERQRVEILRALMTKP 155
Cdd:TIGR02633  81 VIIHQELTLVPELSVAENIFLGneitLPGGRMAyNAMYLRAKNLLRELQLDADNVTrPVGDYGGGQQQLVEIAKALNKQA 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 156 KLLILDEPTSVLTPQAVRKLFKTLHQLSSEGVSILFISHKLDEIRELADRCVVLRAGKVVASVDPKAESEENLARLMIGn 235
Cdd:TIGR02633 161 RLLILDEPSSSLTEKETEILLDIIRDLKAHGVACVYISHKLNEVKAVCDTICVIRDGQHVATKDMSTMSEDDIITMMVG- 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 236 dpptvREGTA-------KAGEVVFEMRHVSA--PGSTRVCGIDNVSLAVRAGEIVGIAGISGNGQARFMAAASGEY--LC 304
Cdd:TIGR02633 240 -----REITSlyphephEIGDVILEARNLTCwdVINPHRKRVDDVSFSLRRGEILGVAGLVGAGRTELVQALFGAYpgKF 314

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 305 EADrVLLFNSPVgELDTHARRI-SGLRYVPEQRLGHAAVPELSLTANTYLTgdSLVRSGFILRDRARSFANLV---IERF 380
Cdd:TIGR02633 315 EGN-VFINGKPV-DIRNPAQAIrAGIAMVPEDRKRHGIVPILGVGKNITLS--VLKSFCFKMRIDAAAELQIIgsaIQRL 390

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 381 HVKTPNAEKAAGSLSGGNLQKFIMGREILNRPRVLLVHQPTWGVDVGAAAVIRNSLIRLRDDGAAIIVVSEEIDELFEIS 460
Cdd:TIGR02633 391 KVKTASPFLPIGRLSGGNQQKAVLAKMLLTNPRVLILDEPTRGVDVGAKYEIYKLINQLAQEGVAIIVVSSELAEVLGLS 470

                         490
                  ....*....|.
gi 2549828669 461 DRIAVMYRGAL 471
Cdd:TIGR02633 471 DRVLVIGEGKL 481

ABC_Carb_Monos_I

cd03216

First domain of the ATP-binding cassette component of monosaccharide transport system; This ...

5-217

1.68e-81

First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.

Pssm-ID: 213183 [Multi-domain] Cd Length: 163 Bit Score: 250.42 E-value: 1.68e-81

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   5 LSLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQARELGIAMV 84
Cdd:cd03216     1 LELRGITKRFGGVKALDGVSLSVRRGEVHALLGENGAGKSTLMKILSGLYKPDSGEILVDGKEVSFASPRDARRAGIAMV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  85 HQhfalfdtlsvtenvalglstgisaaeiereirllgekyglevdpasvvmeLSMGERQRVEILRALMTKPKLLILDEPT 164
Cdd:cd03216    81 YQ--------------------------------------------------LSVGERQMVEIARALARNARLLILDEPT 110

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2549828669 165 SVLTPQAVRKLFKTLHQLSSEGVSILFISHKLDEIRELADRCVVLRAGKVVAS 217
Cdd:cd03216   111 AALTPAEVERLFKVIRRLRAQGVAVIFISHRLDEVFEIADRVTVLRDGRVVGT 163

ABC_tran

pfam00005

ABC transporter; ABC transporters for a large family of proteins responsible for translocation ...

21-165

3.07e-45

ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.

Pssm-ID: 394964 [Multi-domain] Cd Length: 150 Bit Score: 155.50 E-value: 3.07e-45

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  21 DHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQARElGIAMVHQHFALFDTLSVTENV 100
Cdd:pfam00005   2 KNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQDLTDDERKSLRK-EIGYVFQDPQLFPRLTVRENL 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 101 ALGLS-TGISAAEIEREIRLLGEKYGLEVDPASVVM----ELSMGERQRVEILRALMTKPKLLILDEPTS 165
Cdd:pfam00005  81 RLGLLlKGLSKREKDARAEEALEKLGLGDLADRPVGerpgTLSGGQRQRVAIARALLTKPKLLLLDEPTA 150

AztA

NF040873

zinc ABC transporter ATP-binding protein AztA;

13-209

1.69e-27

zinc ABC transporter ATP-binding protein AztA;

Pssm-ID: 468810 [Multi-domain] Cd Length: 191 Bit Score: 108.86 E-value: 1.69e-27

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  13 RYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEIsfdghplgvetpAQARELGIAMVHQHFALFD 92
Cdd:NF040873    1 GYGGRPVLHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLRPTSGTV------------RRAGGARVAYVPQRSEVPD 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  93 TLSVT--ENVALGL---------STGISAAEIEREIRLLGEKyGLEVDPASvvmELSMGERQRVEILRALMTKPKLLILD 161
Cdd:NF040873   69 SLPLTvrDLVAMGRwarrglwrrLTRDDRAAVDDALERVGLA-DLAGRQLG---ELSGGQRQRALLAQGLAQEADLLLLD 144

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 2549828669 162 EPTSVLTPQAVRKLFKTLHQLSSEGVSILFISHKLDEIReLADRCVVL 209
Cdd:NF040873  145 EPTTGLDAESRERIIALLAEEHARGATVVVVTHDLELVR-RADPCVLL 191

ABC2_perm_RbbA

ribosome-associated ATPase/putative transporter RbbA;

8-222

6.65e-23

ribosome-associated ATPase/putative transporter RbbA;

Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 102.90 E-value: 6.65e-23

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   8 RNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGvetpaqARELGIAM---- 83
Cdd:NF033858  270 RGLTMRFGDFTAVDHVSFRIRRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGEAWLFGQPVD------AGDIATRRrvgy 343

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  84 VHQHFALFDTLSVTENVALG--LsTGISAAEIEREIRLLGEKYGLE--VD--PASvvmeLSMGERQRVEILRALMTKPKL 157
Cdd:NF033858  344 MSQAFSLYGELTVRQNLELHarL-FHLPAAEIAARVAEMLERFDLAdvADalPDS----LPLGIRQRLSLAVAVIHKPEL 418

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2549828669 158 LILDEPTSVLTPQAvRKLF-KTLHQLSSE-GVSIlFIS-HKLDEIrELADRCVVLRAGKVVASVDPKA 222
Cdd:NF033858  419 LILDEPTSGVDPVA-RDMFwRLLIELSREdGVTI-FIStHFMNEA-ERCDRISLMHAGRVLASDTPAA 483

ABC2_perm_RbbA

ribosome-associated ATPase/putative transporter RbbA;

6-469

4.52e-18

ribosome-associated ATPase/putative transporter RbbA;

Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 87.49 E-value: 4.52e-18

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   6 SLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLgvetpAQARELgiAMVH 85
Cdd:NF033858    3 RLEGVSHRYGKTVALDDVSLDIPAGCMVGLIGPDGVGKSSLLSLIAGARKIQQGRVEVLGGDM-----ADARHR--RAVC 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  86 QHFA---------LFDTLSVTENVAL-GLSTGISAAEIEREIRLLGEKYGLE--VD-PASvvmELSMGERQRVEILRALM 152
Cdd:NF033858   76 PRIAympqglgknLYPTLSVFENLDFfGRLFGQDAAERRRRIDELLRATGLApfADrPAG---KLSGGMKQKLGLCCALI 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 153 TKPKLLILDEPTSVLTPQAvRKLFKTL---HQLSSEGVSILFISHKLDEIrELADRCVVLRAGKVVASVDPK-------A 222
Cdd:NF033858  153 HDPDLLILDEPTTGVDPLS-RRQFWELidrIRAERPGMSVLVATAYMEEA-ERFDWLVAMDAGRVLATGTPAellartgA 230

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 223 ES-EENLARLMigndPPTVREGTA----------KAGEVVFEMRHVsapgsTRVCG----IDNVSLAVRAGEIVGIAGIS 287
Cdd:NF033858  231 DTlEAAFIALL----PEEKRRGHQpvvipprpadDDDEPAIEARGL-----TMRFGdftaVDHVSFRIRRGEIFGFLGSN 301

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 288 GNGQARFM-------AAASGEylceadrVLLFNSPV---------------------GE------LDTHARrisgLRYVP 333
Cdd:NF033858  302 GCGKSTTMkmltgllPASEGE-------AWLFGQPVdagdiatrrrvgymsqafslyGEltvrqnLELHAR----LFHLP 370

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 334 EQRLGhAAVPELsltantyltgdslvrsgfilrdrarsfanlvIERFHVkTPNAEKAAGSLSGGNLQKFIMGREILNRPR 413
Cdd:NF033858  371 AAEIA-ARVAEM-------------------------------LERFDL-ADVADALPDSLPLGIRQRLSLAVAVIHKPE 417

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2549828669 414 VLLVHQPTWGVDVGAaaviRNS----LIRL-RDDGAAIIVVSEEIDELfEISDRIAVMYRG 469
Cdd:NF033858  418 LLILDEPTSGVDPVA----RDMfwrlLIELsREDGVTIFISTHFMNEA-ERCDRISLMHAG 473

40850658_otr

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;

5-216

1.08e-12

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;

Pssm-ID: 411078 [Multi-domain] Cd Length: 351 Bit Score: 69.38 E-value: 1.08e-12

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   5 LSLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAG--KSTLMKIIYGaarPDEGEISFDGHPLGVETPAQARELGIa 82
Cdd:NF000106   14 VEVRGLVKHFGEVKAVDGVDLDVREGTVLGVLGP*GAA**RGALPAHV*G---PDAGRRPWRF*TWCANRRALRRTIG*- 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  83 mvHQ--HFALFDTLSVTENV-ALGLSTGISAAEIEREIRLLGEKYGLEVDPASVVMELSMGERQRVEILRALMTKPKLLI 159
Cdd:NF000106   90 --HRpvR*GRRESFSGRENLyMIGR*LDLSRKDARARADELLERFSLTEAAGRAAAKYSGGMRRRLDLAASMIGRPAVLY 167

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2549828669 160 LDEPTSVLTPQAVRKLFKTLHQLSSEGVSILFISHKLDEIRELADRCVVLRAGKVVA 216
Cdd:NF000106  168 LDEPTTGLDPRTRNEVWDEVRSMVRDGATVLLTTQYMEEAEQLAHELTVIDRGRVIA 224

40850658_otr

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;

239-469

1.14e-10

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;

Pssm-ID: 411078 [Multi-domain] Cd Length: 351 Bit Score: 63.22 E-value: 1.14e-10

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 239 TVREGTAKAGEVVFEMRHVSapgstRVCGIDNVSLAVRAGEIVGIAGISGNGQARFMAAASGEYLCEADRVLLFNSPVGE 318
Cdd:NF000106    5 TISNGARNAVEVRGLVKHFG-----EVKAVDGVDLDVREGTVLGVLGP*GAA**RGALPAHV*GPDAGRRPWRF*TWCAN 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 319 LDTHARRISGLRYVpeqRLGHAAvpELSLTANTYLTGDSLVRSgfilRDRARSFANLVIERFHVkTPNAEKAAGSLSGGN 398
Cdd:NF000106   80 RRALRRTIG*HRPV---R*GRRE--SFSGRENLYMIGR*LDLS----RKDARARADELLERFSL-TEAAGRAAAKYSGGM 149

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2549828669 399 LQKFIMGREILNRPRVLLVHQPTWGVDVGAAAVIRNSLIRLRDDGAAIIVVSEEIDELFEISDRIAVMYRG 469
Cdd:NF000106  150 RRRLDLAASMIGRPAVLYLDEPTTGLDPRTRNEVWDEVRSMVRDGATVLLTTQYMEEAEQLAHELTVIDRG 220

AAA

smart00382

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...

29-205

1.26e-05

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.

Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 45.06 E-value: 1.26e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   29 PGEVLAILGENGAGKSTLMKIIYGAARPDEGEIsfdghplgvetpaqarelgiamvhqhfalfdtlsvtenVALGLSTGI 108
Cdd:smart00382   1 PGEVILIVGPPGSGKTTLARALARELGPPGGGV--------------------------------------IYIDGEDIL 42

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  109 SAAEIEREIRLLGEKYGLEVDpasvvmelsmGERQRVEILRALMTKPKLLILDEPTSVLTPQAVRKLFKTLH------QL 182
Cdd:smart00382  43 EEVLDQLLLIIVGGKKASGSG----------ELRLRLALALARKLKPDVLILDEITSLLDAEQEALLLLLEElrllllLK 112

                          170       180
                   ....*....|....*....|...
gi 2549828669  183 SSEGVSILFISHKLDEIRELADR 205
Cdd:smart00382 113 SEKNLTVILTTNDEKDLGPALLR 135

Name

Accession

Description

Interval

E-value

NupO

COG3845

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ...

1-495

0e+00

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];

Pssm-ID: 443055 [Multi-domain] Cd Length: 504 Bit Score: 707.56 E-value: 0e+00

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   1 MTPRLSLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQARELG 80
Cdd:COG3845     2 MPPALELRGITKRFGGVVANDDVSLTVRPGEIHALLGENGAGKSTLMKILYGLYQPDSGEILIDGKPVRIRSPRDAIALG 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  81 IAMVHQHFALFDTLSVTENVALGLSTG----ISAAEIEREIRLLGEKYGLEVDPASVVMELSMGERQRVEILRALMTKPK 156
Cdd:COG3845    82 IGMVHQHFMLVPNLTVAENIVLGLEPTkggrLDRKAARARIRELSERYGLDVDPDAKVEDLSVGEQQRVEILKALYRGAR 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 157 LLILDEPTSVLTPQAVRKLFKTLHQLSSEGVSILFISHKLDEIRELADRCVVLRAGKVVASVDPKAESEENLARLMIGND 236
Cdd:COG3845   162 ILILDEPTAVLTPQEADELFEILRRLAAEGKSIIFITHKLREVMAIADRVTVLRRGKVVGTVDTAETSEEELAELMVGRE 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 237 -PPTVREGTAKAGEVVFEMRHVSAPGSTRVCGIDNVSLAVRAGEIVGIAGISGNGQARFMAAASGEYLCEADRVLLFNSP 315
Cdd:COG3845   242 vLLRVEKAPAEPGEVVLEVENLSVRDDRGVPALKDVSLEVRAGEILGIAGVAGNGQSELAEALAGLRPPASGSIRLDGED 321

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 316 VGELDTHARRISGLRYVPEQRLGHAAVPELSLTANTYLT---GDSLVRSGFILRDRARSFANLVIERFHVKTPNAEKAAG 392
Cdd:COG3845   322 ITGLSPRERRRLGVAYIPEDRLGRGLVPDMSVAENLILGryrRPPFSRGGFLDRKAIRAFAEELIEEFDVRTPGPDTPAR 401

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 393 SLSGGNLQKFIMGREILNRPRVLLVHQPTWGVDVGAAAVIRNSLIRLRDDGAAIIVVSEEIDELFEISDRIAVMYRGALS 472
Cdd:COG3845   402 SLSGGNQQKVILARELSRDPKLLIAAQPTRGLDVGAIEFIHQRLLELRDAGAAVLLISEDLDEILALSDRIAVMYEGRIV 481

                         490       500
                  ....*....|....*....|...
gi 2549828669 473 PAVPKPTISIEEVGRWMSGLWPD 495
Cdd:COG3845   482 GEVPAAEATREEIGLLMAGVKEE 504

MglA

COG1129

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];

1-491

3.36e-173

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];

Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 497.23 E-value: 3.36e-173

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   1 MTPRLSLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQARELG 80
Cdd:COG1129     1 AEPLLEMRGISKSFGGVKALDGVSLELRPGEVHALLGENGAGKSTLMKILSGVYQPDSGEILLDGEPVRFRSPRDAQAAG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  81 IAMVHQHFALFDTLSVTENVALG--LSTG--ISAAEIEREIRLLGEKYGLEVDPASVVMELSMGERQRVEILRALMTKPK 156
Cdd:COG1129    81 IAIIHQELNLVPNLSVAENIFLGrePRRGglIDWRAMRRRARELLARLGLDIDPDTPVGDLSVAQQQLVEIARALSRDAR 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 157 LLILDEPTSVLTPQAVRKLFKTLHQLSSEGVSILFISHKLDEIRELADRCVVLRAGKVVASVDPKAESEENLARLMIGND 236
Cdd:COG1129   161 VLILDEPTASLTEREVERLFRIIRRLKAQGVAIIYISHRLDEVFEIADRVTVLRDGRLVGTGPVAELTEDELVRLMVGRE 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 237 PPTVR-EGTAKAGEVVFEMRHVSAPGstrvcGIDNVSLAVRAGEIVGIAGISGNGQARFMAAASGEYLCEADRVLLFNSP 315
Cdd:COG1129   241 LEDLFpKRAAAPGEVVLEVEGLSVGG-----VVRDVSFSVRAGEILGIAGLVGAGRTELARALFGADPADSGEIRLDGKP 315

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 316 VGELDTHARRISGLRYVPEQRLGHAAVPELSLTANTYLTG-DSLVRSGFILRDRARSFANLVIERFHVKTPNAEKAAGSL 394
Cdd:COG1129   316 VRIRSPRDAIRAGIAYVPEDRKGEGLVLDLSIRENITLASlDRLSRGGLLDRRRERALAEEYIKRLRIKTPSPEQPVGNL 395

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 395 SGGNLQKFIMGREILNRPRVLLVHQPTWGVDVGAAAVIRNSLIRLRDDGAAIIVVSEEIDELFEISDRIAVMYRGALSPA 474
Cdd:COG1129   396 SGGNQQKVVLAKWLATDPKVLILDEPTRGIDVGAKAEIYRLIRELAAEGKAVIVISSELPELLGLSDRILVMREGRIVGE 475

                         490
                  ....*....|....*..
gi 2549828669 475 VPKPTISIEEVGRWMSG 491
Cdd:COG1129   476 LDREEATEEAIMAAATG 492

PRK13549

xylose transporter ATP-binding subunit; Provisional

1-471

1.94e-114

xylose transporter ATP-binding subunit; Provisional

Pssm-ID: 184134 [Multi-domain] Cd Length: 506 Bit Score: 347.30 E-value: 1.94e-114

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   1 MTPRLSLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKII-----YGAArpdEGEISFDGHPLGVETPAQ 75
Cdd:PRK13549    2 MEYLLEMKNITKTFGGVKALDNVSLKVRAGEIVSLCGENGAGKSTLMKVLsgvypHGTY---EGEIIFEGEELQASNIRD 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  76 ARELGIAMVHQHFALFDTLSVTENVALG--LSTG--ISAAEIEREIRLLGEKYGLEVDPASVVMELSMGERQRVEILRAL 151
Cdd:PRK13549   79 TERAGIAIIHQELALVKELSVLENIFLGneITPGgiMDYDAMYLRAQKLLAQLKLDINPATPVGNLGLGQQQLVEIAKAL 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 152 MTKPKLLILDEPTSVLTPQAVRKLFKTLHQLSSEGVSILFISHKLDEIRELADRCVVLRAGKVVASVDPKAESEENLARL 231
Cdd:PRK13549  159 NKQARLLILDEPTASLTESETAVLLDIIRDLKAHGIACIYISHKLNEVKAISDTICVIRDGRHIGTRPAAGMTEDDIITM 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 232 MIGndpptvREGTA-------KAGEVVFEMRHVSA--PGSTRVCGIDNVSLAVRAGEIVGIAGISGNGQARFMAAASGEY 302
Cdd:PRK13549  239 MVG------RELTAlyprephTIGEVILEVRNLTAwdPVNPHIKRVDDVSFSLRRGEILGIAGLVGAGRTELVQCLFGAY 312

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 303 --LCEADrVLLFNSPVgELDTHARRIS-GLRYVPEQRLGHAAVPELSLTANTYLTG-DSLVRSGFILRDRARSFANLVIE 378
Cdd:PRK13549  313 pgRWEGE-IFIDGKPV-KIRNPQQAIAqGIAMVPEDRKRDGIVPVMGVGKNITLAAlDRFTGGSRIDDAAELKTILESIQ 390

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 379 RFHVKTPNAEKAAGSLSGGNLQKFIMGREILNRPRVLLVHQPTWGVDVGAAAVIRNSLIRLRDDGAAIIVVSEEIDELFE 458
Cdd:PRK13549  391 RLKVKTASPELAIARLSGGNQQKAVLAKCLLLNPKILILDEPTRGIDVGAKYEIYKLINQLVQQGVAIIVISSELPEVLG 470

                         490
                  ....*....|...
gi 2549828669 459 ISDRIAVMYRGAL 471
Cdd:PRK13549  471 LSDRVLVMHEGKL 483

PRK15439

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional

1-506

6.38e-103

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional

Pssm-ID: 185336 [Multi-domain] Cd Length: 510 Bit Score: 317.76 E-value: 6.38e-103

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   1 MTPRLSLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQARELG 80
Cdd:PRK15439    8 APPLLCARSISKQYSGVEVLKGIDFTLHAGEVHALLGGNGAGKSTLMKIIAGIVPPDSGTLEIGGNPCARLTPAKAHQLG 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  81 IAMVHQHFALFDTLSVTENVALGLSTgiSAAEIEREIRLLGEkYGLEVDPASVVMELSMGERQRVEILRALMTKPKLLIL 160
Cdd:PRK15439   88 IYLVPQEPLLFPNLSVKENILFGLPK--RQASMQKMKQLLAA-LGCQLDLDSSAGSLEVADRQIVEILRGLMRDSRILIL 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 161 DEPTSVLTPQAVRKLFKTLHQLSSEGVSILFISHKLDEIRELADRCVVLRAGKVVASVDPKAESEENLARLMigndPPTV 240
Cdd:PRK15439  165 DEPTASLTPAETERLFSRIRELLAQGVGIVFISHKLPEIRQLADRISVMRDGTIALSGKTADLSTDDIIQAI----TPAA 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 241 REGTAKAGEVVF----EMRHVSAPGST--RVC-----GIDNVSLAVRAGEIVGIAGISGNGQARFMAAASGEYLCEADRV 309
Cdd:PRK15439  241 REKSLSASQKLWlelpGNRRQQAAGAPvlTVEdltgeGFRNISLEVRAGEILGLAGVVGAGRTELAETLYGLRPARGGRI 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 310 LLFNSPVGELDTHARRISGLRYVPEQRLGHAAVPELSLTANTYltgdSLV--RSGFILRdRARSFAnlVIERFH----VK 383
Cdd:PRK15439  321 MLNGKEINALSTAQRLARGLVYLPEDRQSSGLYLDAPLAWNVC----ALThnRRGFWIK-PARENA--VLERYRralnIK 393

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 384 TPNAEKAAGSLSGGNLQKFIMGREILNRPRVLLVHQPTWGVDVGAAAVIRNSLIRLRDDGAAIIVVSEEIDELFEISDRI 463
Cdd:PRK15439  394 FNHAEQAARTLSGGNQQKVLIAKCLEASPQLLIVDEPTRGVDVSARNDIYQLIRSIAAQNVAVLFISSDLEEIEQMADRV 473

                         490       500       510       520
                  ....*....|....*....|....*....|....*....|...
gi 2549828669 464 AVMYRGALSPAVPKPTISIEEVGRWMSGlwpdspfTQKTSEAH 506
Cdd:PRK15439  474 LVMHQGEISGALTGAAINVDTIMRLAFG-------EHQAQEAS 509

araG

PRK11288

L-arabinose ABC transporter ATP-binding protein AraG;

1-478

3.35e-101

L-arabinose ABC transporter ATP-binding protein AraG;

Pssm-ID: 183077 [Multi-domain] Cd Length: 501 Bit Score: 313.00 E-value: 3.35e-101

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   1 MTPRLSLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQARELG 80
Cdd:PRK11288    1 SSPYLSFDGIGKTFPGVKALDDISFDCRAGQVHALMGENGAGKSTLLKILSGNYQPDAGSILIDGQEMRFASTTAALAAG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  81 IAMVHQHFALFDTLSVTENVALG-LSTG---ISAAEIEREIRLLGEKYGLEVDPASVVMELSMGERQRVEILRALMTKPK 156
Cdd:PRK11288   81 VAIIYQELHLVPEMTVAENLYLGqLPHKggiVNRRLLNYEAREQLEHLGVDIDPDTPLKYLSIGQRQMVEIAKALARNAR 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 157 LLILDEPTSVLTPQAVRKLFKTLHQLSSEGVSILFISHKLDEIRELADRCVVLRAGKVVASVDPKAE-SEENLARLMIGN 235
Cdd:PRK11288  161 VIAFDEPTSSLSAREIEQLFRVIRELRAEGRVILYVSHRMEEIFALCDAITVFKDGRYVATFDDMAQvDRDQLVQAMVGR 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 236 DPPTV-----REgtakAGEVVFEMRHVSAPGSTrvcgiDNVSLAVRAGEIVGIAGISGNGQARFMAAASGEYLCEADRVL 310
Cdd:PRK11288  241 EIGDIygyrpRP----LGEVRLRLDGLKGPGLR-----EPISFSVRAGEIVGLFGLVGAGRSELMKLLYGATRRTAGQVY 311

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 311 LFNSPVGELDTHARRISGLRYVPEQRLGHAAVPELSLTANTYLTG-DSLVRSGFILRDRA-RSFANLVIERFHVKTPNAE 388
Cdd:PRK11288  312 LDGKPIDIRSPRDAIRAGIMLCPEDRKAEGIIPVHSVADNINISArRHHLRAGCLINNRWeAENADRFIRSLNIKTPSRE 391

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 389 KAAGSLSGGNLQKFIMGREILNRPRVLLVHQPTWGVDVGAAAVIRNSLIRLRDDGAAIIVVSEEIDELFEISDRIAVMYR 468
Cdd:PRK11288  392 QLIMNLSGGNQQKAILGRWLSEDMKVILLDEPTRGIDVGAKHEIYNVIYELAAQGVAVLFVSSDLPEVLGVADRIVVMRE 471

                         490
                  ....*....|
gi 2549828669 469 GALSPAVPKP 478
Cdd:PRK11288  472 GRIAGELARE 481

PRK10762

D-ribose transporter ATP binding protein; Provisional

1-472

1.24e-100

D-ribose transporter ATP binding protein; Provisional

Pssm-ID: 236755 [Multi-domain] Cd Length: 501 Bit Score: 311.55 E-value: 1.24e-100

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   1 MTPRLSLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQARELG 80
Cdd:PRK10762    1 MQALLQLKGIDKAFPGVKALSGAALNVYPGRVMALVGENGAGKSTMMKVLTGIYTRDAGSILYLGKEVTFNGPKSSQEAG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  81 IAMVHQHFALFDTLSVTENVALGLST-----GISAAEIEREIRLLGEKYGLEVDPASVVMELSMGERQRVEILRALMTKP 155
Cdd:PRK10762   81 IGIIHQELNLIPQLTIAENIFLGREFvnrfgRIDWKKMYAEADKLLARLNLRFSSDKLVGELSIGEQQMVEIAKVLSFES 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 156 KLLILDEPTSVLTPQAVRKLFKTLHQLSSEGVSILFISHKLDEIRELADRCVVLRAGKVVASVDPKAESEENLARLMIG- 234
Cdd:PRK10762  161 KVIIMDEPTDALTDTETESLFRVIRELKSQGRGIVYISHRLKEIFEICDDVTVFRDGQFIAEREVADLTEDSLIEMMVGr 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 235 ---------NDPPtvregtakaGEVVFEMRHVSAPgstrvcGIDNVSLAVRAGEIVGIAGISGNGQARFMAAASGEYLCE 305
Cdd:PRK10762  241 kledqyprlDKAP---------GEVRLKVDNLSGP------GVNDVSFTLRKGEILGVSGLMGAGRTELMKVLYGALPRT 305

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 306 ADRVLLFNSPVGELDTHARRISGLRYVPEQRLGHAAVPELSLTANTYLTG-DSLVRSGFILRDRARSFA-NLVIERFHVK 383
Cdd:PRK10762  306 SGYVTLDGHEVVTRSPQDGLANGIVYISEDRKRDGLVLGMSVKENMSLTAlRYFSRAGGSLKHADEQQAvSDFIRLFNIK 385

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 384 TPNAEKAAGSLSGGNLQKFIMGREILNRPRVLLVHQPTWGVDVGAAAVIRNSLIRLRDDGAAIIVVSEEIDELFEISDRI 463
Cdd:PRK10762  386 TPSMEQAIGLLSGGNQQKVAIARGLMTRPKVLILDEPTRGVDVGAKKEIYQLINQFKAEGLSIILVSSEMPEVLGMSDRI 465


                  ....*....
gi 2549828669 464 AVMYRGALS 472
Cdd:PRK10762  466 LVMHEGRIS 474

PRK09700

D-allose ABC transporter ATP-binding protein AlsA;

1-488

1.23e-99

D-allose ABC transporter ATP-binding protein AlsA;

Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 309.41 E-value: 1.23e-99

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   1 MTPRLSLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQARELG 80
Cdd:PRK09700    2 ATPYISMAGIGKSFGPVHALKSVNLTVYPGEIHALLGENGAGKSTLMKVLSGIHEPTKGTITINNINYNKLDHKLAAQLG 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  81 IAMVHQHFALFDTLSVTENVALG-LSTG-------ISAAEIEREIRLLGEKYGLEVDPASVVMELSMGERQRVEILRALM 152
Cdd:PRK09700   82 IGIIYQELSVIDELTVLENLYIGrHLTKkvcgvniIDWREMRVRAAMMLLRVGLKVDLDEKVANLSISHKQMLEIAKTLM 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 153 TKPKLLILDEPTSVLTPQAVRKLFKTLHQLSSEGVSILFISHKLDEIRELADRCVVLRAGKVVASVDPKAESEENLARLM 232
Cdd:PRK09700  162 LDAKVIIMDEPTSSLTNKEVDYLFLIMNQLRKEGTAIVYISHKLAEIRRICDRYTVMKDGSSVCSGMVSDVSNDDIVRLM 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 233 IGNDP----PTVREGTAK-AGEVVFEMRHVSAPGSTRVcgiDNVSLAVRAGEIVGIAGISGNGQARFMAA-------ASG 300
Cdd:PRK09700  242 VGRELqnrfNAMKENVSNlAHETVFEVRNVTSRDRKKV---RDISFSVCRGEILGFAGLVGSGRTELMNClfgvdkrAGG 318

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 301 EYLCEADRVllfnSPVGELDTHARrisGLRYVPEQRLGHAAVPELSLTANTYLTgDSLVRSGF-----ILRDR-ARSFAN 374
Cdd:PRK09700  319 EIRLNGKDI----SPRSPLDAVKK---GMAYITESRRDNGFFPNFSIAQNMAIS-RSLKDGGYkgamgLFHEVdEQRTAE 390

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 375 LVIERFHVKTPNAEKAAGSLSGGNLQKFIMGREILNRPRVLLVHQPTWGVDVGAAAVIRNSLIRLRDDGAAIIVVSEEID 454
Cdd:PRK09700  391 NQRELLALKCHSVNQNITELSGGNQQKVLISKWLCCCPEVIIFDEPTRGIDVGAKAEIYKVMRQLADDGKVILMVSSELP 470

                         490       500       510
                  ....*....|....*....|....*....|....*
gi 2549828669 455 ELFEISDRIAVMYRGALSPAVP-KPTISIEEVGRW 488
Cdd:PRK09700  471 EIITVCDRIAVFCEGRLTQILTnRDDMSEEEIMAW 505

GguA

NF040905

sugar ABC transporter ATP-binding protein;

5-489

6.38e-97

sugar ABC transporter ATP-binding protein;

Pssm-ID: 468840 [Multi-domain] Cd Length: 500 Bit Score: 302.09 E-value: 6.38e-97

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   5 LSLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYG--AARPDEGEISFDGHPLGVETPAQARELGIA 82
Cdd:NF040905    2 LEMRGITKTFPGVKALDDVNLSVREGEIHALCGENGAGKSTLMKVLSGvyPHGSYEGEILFDGEVCRFKDIRDSEALGIV 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  83 MVHQHFALFDTLSVTENVALGLSTG----ISAAEIEREIRLLGEKYGLEVDPASVVMELSMGERQRVEILRALMTKPKLL 158
Cdd:NF040905   82 IIHQELALIPYLSIAENIFLGNERAkrgvIDWNETNRRARELLAKVGLDESPDTLVTDIGVGKQQLVEIAKALSKDVKLL 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 159 ILDEPTSVLTPQAVRKLFKTLHQLSSEGVSILFISHKLDEIRELADRCVVLRAGKVVASVDPKAE--SEENLARLMIGND 236
Cdd:NF040905  162 ILDEPTAALNEEDSAALLDLLLELKAQGITSIIISHKLNEIRRVADSITVLRDGRTIETLDCRADevTEDRIIRGMVGRD 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 237 -----PPTvregTAKAGEVVFEMRHVSA--PG-STRVCgIDNVSLAVRAGEIVGIAGISGNGQARFMAA---------AS 299
Cdd:NF040905  242 ledryPER----TPKIGEVVFEVKNWTVyhPLhPERKV-VDDVSLNVRRGEIVGIAGLMGAGRTELAMSvfgrsygrnIS 316

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 300 GEylceadrVLLFNSPVgELDTHARRI-SGLRYVPEQRLGHAAVPELSLTANTYLTG-DSLVRSGFILRDRARSFANLVI 377
Cdd:NF040905  317 GT-------VFKDGKEV-DVSTVSDAIdAGLAYVTEDRKGYGLNLIDDIKRNITLANlGKVSRRGVIDENEEIKVAEEYR 388

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 378 ERFHVKTPNAEKAAGSLSGGNLQKFIMGREILNRPRVLLVHQPTWGVDVGAAAVIRNSLIRLRDDGAAIIVVSEEIDELF 457
Cdd:NF040905  389 KKMNIKTPSVFQKVGNLSGGNQQKVVLSKWLFTDPDVLILDEPTRGIDVGAKYEIYTIINELAAEGKGVIVISSELPELL 468

                         490       500       510
                  ....*....|....*....|....*....|..
gi 2549828669 458 EISDRIAVMYRGALSPAVPKPTISIEEVGRWM 489
Cdd:NF040905  469 GMCDRIYVMNEGRITGELPREEASQERIMRLI 500

xylG

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ...

5-471

4.06e-92

Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 289.80 E-value: 4.06e-92

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   5 LSLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAaRPD---EGEISFDGHPLGVETPAQARELGI 81
Cdd:TIGR02633   2 LEMKGIVKTFGGVKALDGIDLEVRPGECVGLCGENGAGKSTLMKILSGV-YPHgtwDGEIYWSGSPLKASNIRDTERAGI 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  82 AMVHQHFALFDTLSVTENVALG----LSTGISA-AEIEREIRLLGEKYGLEVDPAS-VVMELSMGERQRVEILRALMTKP 155
Cdd:TIGR02633  81 VIIHQELTLVPELSVAENIFLGneitLPGGRMAyNAMYLRAKNLLRELQLDADNVTrPVGDYGGGQQQLVEIAKALNKQA 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 156 KLLILDEPTSVLTPQAVRKLFKTLHQLSSEGVSILFISHKLDEIRELADRCVVLRAGKVVASVDPKAESEENLARLMIGn 235
Cdd:TIGR02633 161 RLLILDEPSSSLTEKETEILLDIIRDLKAHGVACVYISHKLNEVKAVCDTICVIRDGQHVATKDMSTMSEDDIITMMVG- 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 236 dpptvREGTA-------KAGEVVFEMRHVSA--PGSTRVCGIDNVSLAVRAGEIVGIAGISGNGQARFMAAASGEY--LC 304
Cdd:TIGR02633 240 -----REITSlyphephEIGDVILEARNLTCwdVINPHRKRVDDVSFSLRRGEILGVAGLVGAGRTELVQALFGAYpgKF 314

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 305 EADrVLLFNSPVgELDTHARRI-SGLRYVPEQRLGHAAVPELSLTANTYLTgdSLVRSGFILRDRARSFANLV---IERF 380
Cdd:TIGR02633 315 EGN-VFINGKPV-DIRNPAQAIrAGIAMVPEDRKRHGIVPILGVGKNITLS--VLKSFCFKMRIDAAAELQIIgsaIQRL 390

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 381 HVKTPNAEKAAGSLSGGNLQKFIMGREILNRPRVLLVHQPTWGVDVGAAAVIRNSLIRLRDDGAAIIVVSEEIDELFEIS 460
Cdd:TIGR02633 391 KVKTASPFLPIGRLSGGNQQKAVLAKMLLTNPRVLILDEPTRGVDVGAKYEIYKLINQLAQEGVAIIVVSSELAEVLGLS 470

                         490
                  ....*....|.
gi 2549828669 461 DRIAVMYRGAL 471
Cdd:TIGR02633 471 DRVLVIGEGKL 481

PRK10982

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional

7-485

7.64e-90

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional

Pssm-ID: 182880 [Multi-domain] Cd Length: 491 Bit Score: 283.54 E-value: 7.64e-90

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   7 LRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQARELGIAMVHQ 86
Cdd:PRK10982    1 MSNISKSFPGVKALDNVNLKVRPHSIHALMGENGAGKSTLLKCLFGIYQKDSGSILFQGKEIDFKSSKEALENGISMVHQ 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  87 HFALFDTLSVTENVALGL----STGISAAEIEREIRLLGEKYGLEVDPASVVMELSMGERQRVEILRALMTKPKLLILDE 162
Cdd:PRK10982   81 ELNLVLQRSVMDNMWLGRyptkGMFVDQDKMYRDTKAIFDELDIDIDPRAKVATLSVSQMQMIEIAKAFSYNAKIVIMDE 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 163 PTSVLTPQAVRKLFKTLHQLSSEGVSILFISHKLDEIRELADRCVVLRAGKVVASVDPKAESEENLARLMIGNDpPTVR- 241
Cdd:PRK10982  161 PTSSLTEKEVNHLFTIIRKLKERGCGIVYISHKMEEIFQLCDEITILRDGQWIATQPLAGLTMDKIIAMMVGRS-LTQRf 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 242 -EGTAKAGEVVFEMRHVSApgsTRVCGIDNVSLAVRAGEIVGIAGISGNGQARFMAAASGEYLCEADRVLLFNSPVGELD 320
Cdd:PRK10982  240 pDKENKPGEVILEVRNLTS---LRQPSIRDVSFDLHKGEILGIAGLVGAKRTDIVETLFGIREKSAGTITLHGKKINNHN 316

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 321 THARRISGLRYVPEQRLGHAAVPELSLTANTYLTGDSLVRSGFILRD--RARSFANLVIERFHVKTPNAEKAAGSLSGGN 398
Cdd:PRK10982  317 ANEAINHGFALVTEERRSTGIYAYLDIGFNSLISNIRNYKNKVGLLDnsRMKSDTQWVIDSMRVKTPGHRTQIGSLSGGN 396

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 399 LQKFIMGREILNRPRVLLVHQPTWGVDVGAAAVIRNSLIRLRDDGAAIIVVSEEIDELFEISDRIAVMYRGALSPAVPKP 478
Cdd:PRK10982  397 QQKVIIGRWLLTQPEILMLDEPTRGIDVGAKFEIYQLIAELAKKDKGIIIISSEMPELLGITDRILVMSNGLVAGIVDTK 476


                  ....*..
gi 2549828669 479 TISIEEV 485
Cdd:PRK10982  477 TTTQNEI 483

ABC_Carb_Monos_I

cd03216

First domain of the ATP-binding cassette component of monosaccharide transport system; This ...

5-217

1.68e-81

Pssm-ID: 213183 [Multi-domain] Cd Length: 163 Bit Score: 250.42 E-value: 1.68e-81

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   5 LSLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQARELGIAMV 84
Cdd:cd03216     1 LELRGITKRFGGVKALDGVSLSVRRGEVHALLGENGAGKSTLMKILSGLYKPDSGEILVDGKEVSFASPRDARRAGIAMV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  85 HQhfalfdtlsvtenvalglstgisaaeiereirllgekyglevdpasvvmeLSMGERQRVEILRALMTKPKLLILDEPT 164
Cdd:cd03216    81 YQ--------------------------------------------------LSVGERQMVEIARALARNARLLILDEPT 110

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2549828669 165 SVLTPQAVRKLFKTLHQLSSEGVSILFISHKLDEIRELADRCVVLRAGKVVAS 217
Cdd:cd03216   111 AALTPAEVERLFKVIRRLRAQGVAVIFISHRLDEVFEIADRVTVLRDGRVVGT 163

GsiA

COG1123

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ...

1-469

2.26e-70

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];

Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 233.26 E-value: 2.26e-70

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   1 MTPRLSLRNITKRYPG--ITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPD---EGEISFDGHPLgVETPAQ 75
Cdd:COG1123     1 MTPLLEVRDLSVRYPGgdVPAVDGVSLTIAPGETVALVGESGSGKSTLALALMGLLPHGgriSGEVLLDGRDL-LELSEA 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  76 ARELGIAMVHQHF-ALFDTLSVTENVALGLS-TGISAAEIEREIRLLGEKYGLEVDPASVVMELSMGERQRVEILRALMT 153
Cdd:COG1123    80 LRGRRIGMVFQDPmTQLNPVTVGDQIAEALEnLGLSRAEARARVLELLEAVGLERRLDRYPHQLSGGQRQRVAIAMALAL 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 154 KPKLLILDEPTSVLTPQAVRKLFKTLHQLSSE-GVSILFISHKLDEIRELADRCVVLRAGKVVASVDPKA--ESEENLAR 230
Cdd:COG1123   160 DPDLLIADEPTTALDVTTQAEILDLLRELQRErGTTVLLITHDLGVVAEIADRVVVMDDGRIVEDGPPEEilAAPQALAA 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 231 LMIGNDPPTVREGTAKAGEVVFEMRHVS----APGSTRVCGIDNVSLAVRAGEIVGIAGISGNGQ-------ARFMAAAS 299
Cdd:COG1123   240 VPRLGAARGRAAPAAAAAEPLLEVRNLSkrypVRGKGGVRAVDDVSLTLRRGETLGLVGESGSGKstlarllLGLLRPTS 319

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 300 GEylceadrVLLFNSPVGELDTHARRisGLR----YVPeQRlghaavPELSLtaNTYLT-----GDSLVRSGFILRDRAR 370
Cdd:COG1123   320 GS-------ILFDGKDLTKLSRRSLR--ELRrrvqMVF-QD------PYSSL--NPRMTvgdiiAEPLRLHGLLSRAERR 381

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 371 SFANLVIERFHVKTPNAEKAAGSLSGGNLQKFIMGREILNRPRVLLVHQPTWGVDVGAAAVIRNSLIRLRDD-GAAIIVV 449
Cdd:COG1123   382 ERVAELLERVGLPPDLADRYPHELSGGQRQRVAIARALALEPKLLILDEPTSALDVSVQAQILNLLRDLQRElGLTYLFI 461

                         490       500
                  ....*....|....*....|
gi 2549828669 450 SEEIDELFEISDRIAVMYRG 469
Cdd:COG1123   462 SHDLAVVRYIADRVAVMYDG 481

CcmA

COG1131

ABC-type multidrug transport system, ATPase component [Defense mechanisms];

5-228

5.31e-66

ABC-type multidrug transport system, ATPase component [Defense mechanisms];

Pssm-ID: 440746 [Multi-domain] Cd Length: 236 Bit Score: 213.00 E-value: 5.31e-66

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   5 LSLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLgVETPAQARELgIAMV 84
Cdd:COG1131     1 IEVRGLTKRYGDKTALDGVSLTVEPGEIFGLLGPNGAGKTTTIRMLLGLLRPTSGEVRVLGEDV-ARDPAEVRRR-IGYV 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  85 HQHFALFDTLSVTENVAL-GLSTGISAAEIEREIRLLGEKYGLEVDPASVVMELSMGERQRVEILRALMTKPKLLILDEP 163
Cdd:COG1131    79 PQEPALYPDLTVRENLRFfARLYGLPRKEARERIDELLELFGLTDAADRKVGTLSGGMKQRLGLALALLHDPELLILDEP 158

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2549828669 164 TSVLTPQAVRKLFKTLHQLSSEGVSILFISHKLDEIRELADRCVVLRAGKVVASVDPKAESEENL 228
Cdd:COG1131   159 TSGLDPEARRELWELLRELAAEGKTVLLSTHYLEEAERLCDRVAIIDKGRIVADGTPDELKARLL 223

ABC_Carb_Monos_II

cd03215

Second domain of the ATP-binding cassette component of monosaccharide transport system; This ...

248-471

1.37e-59

Second domain of the ATP-binding cassette component of monosaccharide transport system; This family represents domain II of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. In members of Carb_Monos family the single hydrophobic gene product forms a homodimer, while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.

Pssm-ID: 213182 [Multi-domain] Cd Length: 182 Bit Score: 194.19 E-value: 1.37e-59

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 248 GEVVFEMRHVSAPGSTRvcgidNVSLAVRAGEIVGIAGISGNGQARFMAAASGEYLCEADRVLLFNSPVGELDTHARRIS 327
Cdd:cd03215     1 GEPVLEVRGLSVKGAVR-----DVSFEVRAGEIVGIAGLVGNGQTELAEALFGLRPPASGEITLDGKPVTRRSPRDAIRA 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 328 GLRYVPEQRLGHAAVPELSLtantyltgdslvrsgfilrdrarsFANLVIERFhvktpnaekaagsLSGGNLQKFIMGRE 407
Cdd:cd03215    76 GIAYVPEDRKREGLVLDLSV------------------------AENIALSSL-------------LSGGNQQKVVLARW 118

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2549828669 408 ILNRPRVLLVHQPTWGVDVGAAAVIRNSLIRLRDDGAAIIVVSEEIDELFEISDRIAVMYRGAL 471
Cdd:cd03215   119 LARDPRVLILDEPTRGVDVGAKAEIYRLIRELADAGKAVLLISSELDELLGLCDRILVMYEGRI 182

LivG

COG0411

ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid ...

1-217

1.20e-58

ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid transport and metabolism];

Pssm-ID: 440180 [Multi-domain] Cd Length: 257 Bit Score: 194.49 E-value: 1.20e-58

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   1 MTPRLSLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQARELG 80
Cdd:COG0411     1 SDPLLEVRGLTKRFGGLVAVDDVSLEVERGEIVGLIGPNGAGKTTLFNLITGFYRPTSGRILFDGRDITGLPPHRIARLG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  81 IAMVHQHFALFDTLSVTENVALG-------------LSTGISAAEiEREIR-----LLgEKYGLEVDPASVVMELSMGER 142
Cdd:COG0411    81 IARTFQNPRLFPELTVLENVLVAaharlgrgllaalLRLPRARRE-EREAReraeeLL-ERVGLADRADEPAGNLSYGQQ 158

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2549828669 143 QRVEILRALMTKPKLLILDEPTSVLTPQAVRKLFKTLHQLSSE-GVSILFISHKLDEIRELADRCVVLRAGKVVAS 217
Cdd:COG0411   159 RRLEIARALATEPKLLLLDEPAAGLNPEETEELAELIRRLRDErGITILLIEHDMDLVMGLADRIVVLDFGRVIAE 234

ABC_DR_subfamily_A

cd03230

ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ...

5-214

1.24e-58

ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213197 [Multi-domain] Cd Length: 173 Bit Score: 191.46 E-value: 1.24e-58

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   5 LSLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGvETPAQARELgIAMV 84
Cdd:cd03230     1 IEVRNLSKRYGKKTALDDISLTVEKGEIYGLLGPNGAGKTTLIKIILGLLKPDSGEIKVLGKDIK-KEPEEVKRR-IGYL 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  85 HQHFALFDTLSVTENValglstgisaaeiereirllgekyglevdpasvvmELSMGERQRVEILRALMTKPKLLILDEPT 164
Cdd:cd03230    79 PEEPSLYENLTVRENL-----------------------------------KLSGGMKQRLALAQALLHDPELLILDEPT 123

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 2549828669 165 SVLTPQAVRKLFKTLHQLSSEGVSILFISHKLDEIRELADRCVVLRAGKV 214
Cdd:cd03230   124 SGLDPESRREFWELLRELKKEGKTILLSSHILEEAERLCDRVAILNNGRI 173

ABC_Mj1267_LivG_branched

cd03219

ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ...

5-220

2.32e-57

ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).

Pssm-ID: 213186 [Multi-domain] Cd Length: 236 Bit Score: 190.34 E-value: 2.32e-57

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   5 LSLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQARELGIAMV 84
Cdd:cd03219     1 LEVRGLTKRFGGLVALDDVSFSVRPGEIHGLIGPNGAGKTTLFNLISGFLRPTSGSVLFDGEDITGLPPHEIARLGIGRT 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  85 HQHFALFDTLSVTENVALGL----STGISAAEIEREIRLLGEK----------YGLEVDPASvvmELSMGERQRVEILRA 150
Cdd:cd03219    81 FQIPRLFPELTVLENVMVAAqartGSGLLLARARREEREARERaeellervglADLADRPAG---ELSYGQQRRLEIARA 157

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 151 LMTKPKLLILDEPTSVLTPQAVRKLFKTLHQLSSEGVSILFISHKLDEIRELADRCVVLRAGKVVASVDP 220
Cdd:cd03219   158 LATDPKLLLLDEPAAGLNPEETEELAELIRELRERGITVLLVEHDMDVVMSLADRVTVLDQGRVIAEGTP 227

EcfA2

COG1122

Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ...

5-222

2.57e-56

Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];

Pssm-ID: 440739 [Multi-domain] Cd Length: 230 Bit Score: 187.54 E-value: 2.57e-56

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   5 LSLRNITKRYP-GITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQARELgIAM 83
Cdd:COG1122     1 IELENLSFSYPgGTPALDDVSLSIEKGEFVAIIGPNGSGKSTLLRLLNGLLKPTSGEVLVDGKDITKKNLRELRRK-VGL 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  84 VHQH-----FALfdtlSVTENVALGLS-TGISAAEIEREIRLLGEKYGLEVDPASVVMELSMGERQRVEILRALMTKPKL 157
Cdd:COG1122    80 VFQNpddqlFAP----TVEEDVAFGPEnLGLPREEIRERVEEALELVGLEHLADRPPHELSGGQKQRVAIAGVLAMEPEV 155

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2549828669 158 LILDEPTSVLTPQAVRKLFKTLHQLSSEGVSILFISHKLDEIRELADRCVVLRAGKVVASVDPKA 222
Cdd:COG1122   156 LVLDEPTAGLDPRGRRELLELLKRLNKEGKTVIIVTHDLDLVAELADRVIVLDDGRIVADGTPRE 220

CysA

COG1118

ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and ...

5-223

7.60e-56

ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism];

Pssm-ID: 440735 [Multi-domain] Cd Length: 348 Bit Score: 189.97 E-value: 7.60e-56

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   5 LSLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQARelGIAMV 84
Cdd:COG1118     3 IEVRNISKRFGSFTLLDDVSLEIASGELVALLGPSGSGKTTLLRIIAGLETPDSGRIVLNGRDLFTNLPPRER--RVGFV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  85 HQHFALFDTLSVTENVALGLST-GISAAEIEREIRLLGEKYGLE----VDPAsvvmELSMGERQRVEILRALMTKPKLLI 159
Cdd:COG1118    81 FQHYALFPHMTVAENIAFGLRVrPPSKAEIRARVEELLELVQLEgladRYPS----QLSGGQRQRVALARALAVEPEVLL 156

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2549828669 160 LDEPTSVLTPQaVRK-----LFKTLHQLsseGVSILFISHKLDEIRELADRCVVLRAGKVVAsVDPKAE 223
Cdd:COG1118   157 LDEPFGALDAK-VRKelrrwLRRLHDEL---GGTTVFVTHDQEEALELADRVVVMNQGRIEQ-VGTPDE 220

NatA

COG4555

ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, ...

5-226

2.29e-55

ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, Inorganic ion transport and metabolism];

Pssm-ID: 443618 [Multi-domain] Cd Length: 243 Bit Score: 185.45 E-value: 2.29e-55

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   5 LSLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLgVETPAQARELgIAMV 84
Cdd:COG4555     2 IEVENLSKKYGKVPALKDVSFTAKDGEITGLLGPNGAGKTTLLRMLAGLLKPDSGSILIDGEDV-RKEPREARRQ-IGVL 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  85 HQHFALFDTLSVTENVA-LGLSTGISAAEIEREIRLLGEKYGLEVDPASVVMELSMGERQRVEILRALMTKPKLLILDEP 163
Cdd:COG4555    80 PDERGLYDRLTVRENIRyFAELYGLFDEELKKRIEELIELLGLEEFLDRRVGELSTGMKKKVALARALVHDPKVLLLDEP 159

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2549828669 164 TSVLTPQAVRKLFKTLHQLSSEGVSILFISHKLDEIRELADRCVVLRAGKVVASVDPKAESEE 226
Cdd:COG4555   160 TNGLDVMARRLLREILRALKKEGKTVLFSSHIMQEVEALCDRVVILHKGKVVAQGSLDELREE 222

ABC_Carb_Solutes_like

cd03259

ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ...

5-216

3.06e-54

ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213226 [Multi-domain] Cd Length: 213 Bit Score: 181.56 E-value: 3.06e-54

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   5 LSLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLgVETPAQARelGIAMV 84
Cdd:cd03259     1 LELKGLSKTYGSVRALDDLSLTVEPGEFLALLGPSGCGKTTLLRLIAGLERPDSGEILIDGRDV-TGVPPERR--NIGMV 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  85 HQHFALFDTLSVTENVALGL-STGISAAEIEREIRLLGEKYGLEVDPASVVMELSMGERQRVEILRALMTKPKLLILDEP 163
Cdd:cd03259    78 FQDYALFPHLTVAENIAFGLkLRGVPKAEIRARVRELLELVGLEGLLNRYPHELSGGQQQRVALARALAREPSLLLLDEP 157

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2549828669 164 TSVLTPQ---AVRKLFKTLHQlsSEGVSILFISHKLDEIRELADRCVVLRAGKVVA 216
Cdd:cd03259   158 LSALDAKlreELREELKELQR--ELGITTIYVTHDQEEALALADRIAVMNEGRIVQ 211

ABC_cobalt_CbiO_domain1

cd03225

First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ...

6-213

4.32e-53

First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.

Pssm-ID: 213192 [Multi-domain] Cd Length: 211 Bit Score: 178.43 E-value: 4.32e-53

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   6 SLRNITKRYPGITAN--DHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQARELgIAM 83
Cdd:cd03225     1 ELKNLSFSYPDGARPalDDISLTIKKGEFVLIVGPNGSGKSTLLRLLNGLLGPTSGEVLVDGKDLTKLSLKELRRK-VGL 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  84 VHQHFAL-FDTLSVTENVALGL-STGISAAEIEREIRLLGEKYGLEVDPASVVMELSMGERQRVEILRALMTKPKLLILD 161
Cdd:cd03225    80 VFQNPDDqFFGPTVEEEVAFGLeNLGLPEEEIEERVEEALELVGLEGLRDRSPFTLSGGQKQRVAIAGVLAMDPDILLLD 159

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2549828669 162 EPTSVLTPQAVRKLFKTLHQLSSEGVSILFISHKLDEIRELADRCVVLRAGK 213
Cdd:cd03225   160 EPTAGLDPAGRRELLELLKKLKAEGKTIIIVTHDLDLLLELADRVIVLEDGK 211

GsiA

COG1123

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ...

2-222

4.73e-53

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];

Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 187.03 E-value: 4.73e-53

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   2 TPRLSLRNITKRYP-----GITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQA 76
Cdd:COG1123   258 EPLLEVRNLSKRYPvrgkgGVRAVDDVSLTLRRGETLGLVGESGSGKSTLARLLLGLLRPTSGSILFDGKDLTKLSRRSL 337

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  77 RELG--IAMVHQH-FA-LFDTLSVTENVALGLS--TGISAAEIEREIRLLGEKYGLEVD-----PAsvvmELSMGERQRV 145
Cdd:COG1123   338 RELRrrVQMVFQDpYSsLNPRMTVGDIIAEPLRlhGLLSRAERRERVAELLERVGLPPDladryPH----ELSGGQRQRV 413

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 146 EILRALMTKPKLLILDEPTSVLTP--QA-VRKLFKTLHQlsSEGVSILFISHKLDEIRELADRCVVLRAGKVVASVDPKA 222
Cdd:COG1123   414 AIARALALEPKLLILDEPTSALDVsvQAqILNLLRDLQR--ELGLTYLFISHDLAVVRYIADRVAVMYDGRIVEDGPTEE 491

ABC_NrtD_SsuB_transporters

cd03293

ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ...

5-219

5.26e-53

ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213260 [Multi-domain] Cd Length: 220 Bit Score: 178.43 E-value: 5.26e-53

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   5 LSLRNITKRYPG----ITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAqarelg 80
Cdd:cd03293     1 LEVRNVSKTYGGgggaVTALEDISLSVEEGEFVALVGPSGCGKSTLLRIIAGLERPTSGEVLVDGEPVTGPGPD------ 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  81 IAMVHQHFALFDTLSVTENVALGLS-TGISAAEIEREIRLLGEKYGLE--VD--PAsvvmELSMGERQRVEILRALMTKP 155
Cdd:cd03293    75 RGYVFQQDALLPWLTVLDNVALGLElQGVPKAEARERAEELLELVGLSgfENayPH----QLSGGMRQRVALARALAVDP 150

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2549828669 156 KLLILDEPTSVLTPQAVRKLFKTLHQLSSE-GVSILFISHKLDEIRELADRCVVL--RAGKVVASVD 219
Cdd:cd03293   151 DVLLLDEPFSALDALTREQLQEELLDIWREtGKTVLLVTHDIDEAVFLADRVVVLsaRPGRIVAEVE 217

ABC_TM1139_LivF_branched

cd03224

ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ...

5-222

5.74e-53

ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.

Pssm-ID: 213191 [Multi-domain] Cd Length: 222 Bit Score: 178.40 E-value: 5.74e-53

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   5 LSLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQARELGIAMV 84
Cdd:cd03224     1 LEVENLNAGYGKSQILFGVSLTVPEGEIVALLGRNGAGKTTLLKTIMGLLPPRSGSIRFDGRDITGLPPHERARAGIGYV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  85 HQHFALFDTLSVTENVALGLSTGISA---AEIEREIRL---LGEKYGlevDPASvvmELSMGERQRVEILRALMTKPKLL 158
Cdd:cd03224    81 PEGRRIFPELTVEENLLLGAYARRRAkrkARLERVYELfprLKERRK---QLAG---TLSGGEQQMLAIARALMSRPKLL 154

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2549828669 159 ILDEPTSVLTPQAVRKLFKTLHQLSSEGVSILFISHKLDEIRELADRCVVLRAGKVVASVDPKA 222
Cdd:cd03224   155 LLDEPSEGLAPKIVEEIFEAIRELRDEGVTILLVEQNARFALEIADRAYVLERGRVVLEGTAAE 218

PotA

COG3842

ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ...

1-281

6.71e-53

ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];

Pssm-ID: 443052 [Multi-domain] Cd Length: 353 Bit Score: 182.61 E-value: 6.71e-53

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   1 MTPRLSLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLgVETPAQARelG 80
Cdd:COG3842     2 AMPALELENVSKRYGDVTALDDVSLSIEPGEFVALLGPSGCGKTTLLRMIAGFETPDSGRILLDGRDV-TGLPPEKR--N 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  81 IAMVHQHFALFDTLSVTENVALGLST-GISAAEIEREIR--L-------LGEKYglevdPAsvvmELSMGERQRVEILRA 150
Cdd:COG3842    79 VGMVFQDYALFPHLTVAENVAFGLRMrGVPKAEIRARVAelLelvglegLADRY-----PH----QLSGGQQQRVALARA 149

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 151 LMTKPKLLILDEPTSVLTPQ---AVRKLFKTLHQlsSEGVSILFISHKLDEIRELADRCVVLRAGKVVASVDPKA--ESE 225
Cdd:COG3842   150 LAPEPRVLLLDEPLSALDAKlreEMREELRRLQR--ELGITFIYVTHDQEEALALADRIAVMNDGRIEQVGTPEEiyERP 227

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2549828669 226 ENL--ARLmIGND---PPTVREGTakAGEVVFEMRHVSAPGSTRVCGIDNVSLAVRAGEIV 281
Cdd:COG3842   228 ATRfvADF-IGEAnllPGTVLGDE--GGGVRTGGRTLEVPADAGLAAGGPVTVAIRPEDIR 285

LolD

COG1136

ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];

1-216

7.15e-53

ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];

Pssm-ID: 440751 [Multi-domain] Cd Length: 227 Bit Score: 178.31 E-value: 7.15e-53

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   1 MTPRLSLRNITKRYP----GITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQ- 75
Cdd:COG1136     1 MSPLLELRNLTKSYGtgegEVTALRGVSLSIEAGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVLIDGQDISSLSEREl 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  76 ----ARELGIamVHQHFALFDTLSVTENVALGLS-TGISAAEIEREIRLLGEKYGLE--VD--PAsvvmELSMGERQRVE 146
Cdd:COG1136    81 arlrRRHIGF--VFQFFNLLPELTALENVALPLLlAGVSRKERRERARELLERVGLGdrLDhrPS----QLSGGQQQRVA 154

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2549828669 147 ILRALMTKPKLLILDEPTSVL---TPQAVRKLFKTLHQlsSEGVSILFISHklD-EIRELADRCVVLRAGKVVA 216
Cdd:COG1136   155 IARALVNRPKLILADEPTGNLdskTGEEVLELLRELNR--ELGTTIVMVTH--DpELAARADRVIRLRDGRIVS 224

PhnC

COG3638

ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and ...

5-231

2.62e-52

ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and metabolism];

Pssm-ID: 442855 [Multi-domain] Cd Length: 249 Bit Score: 177.56 E-value: 2.62e-52

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   5 LSLRNITKRYP-GITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQAREL--GI 81
Cdd:COG3638     3 LELRNLSKRYPgGTPALDDVSLEIERGEFVALIGPSGAGKSTLLRCLNGLVEPTSGEILVDGQDVTALRGRALRRLrrRI 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  82 AMVHQHFALFDTLSVTENVALG----------LSTGISAAEIEREIRLLgEKYGLE---VDPASvvmELSMGERQRVEIL 148
Cdd:COG3638    83 GMIFQQFNLVPRLSVLTNVLAGrlgrtstwrsLLGLFPPEDRERALEAL-ERVGLAdkaYQRAD---QLSGGQQQRVAIA 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 149 RALMTKPKLLILDEPTSVLTPQAVRKLFKTLHQLSSE-GVSILFISHKLDEIRELADRCVVLRAGKVVASVDPKAESEEN 227
Cdd:COG3638   159 RALVQEPKLILADEPVASLDPKTARQVMDLLRRIAREdGITVVVNLHQVDLARRYADRIIGLRDGRVVFDGPPAELTDAV 238


                  ....
gi 2549828669 228 LARL 231
Cdd:COG3638   239 LREI 242

MalK

COG3839

ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism]; ...

4-280

1.62e-51

ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism];

Pssm-ID: 443050 [Multi-domain] Cd Length: 352 Bit Score: 178.73 E-value: 1.62e-51

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   4 RLSLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGvETPAQARelGIAM 83
Cdd:COG3839     3 SLELENVSKSYGGVEALKDIDLDIEDGEFLVLLGPSGCGKSTLLRMIAGLEDPTSGEILIGGRDVT-DLPPKDR--NIAM 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  84 VHQHFALFDTLSVTENVALGLST-GISAAEIEREIR----LLG-EKYgLEVDPAsvvmELSMGERQRVEILRALMTKPKL 157
Cdd:COG3839    80 VFQSYALYPHMTVYENIAFPLKLrKVPKAEIDRRVReaaeLLGlEDL-LDRKPK----QLSGGQRQRVALGRALVREPKV 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 158 LILDEPTSVLTPQ---AVRKLFKTLHQlsSEGVSILFISHKLDEIRELADRCVVLRAGKV--VASVD-----PKaeseeN 227
Cdd:COG3839   155 FLLDEPLSNLDAKlrvEMRAEIKRLHR--RLGTTTIYVTHDQVEAMTLADRIAVMNDGRIqqVGTPEelydrPA-----N 227

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2549828669 228 L--ARLmIGNDPPTVREGTAKAGEVVFEMRHVSAPGSTRVCGIDNVSLAVRAGEI 280
Cdd:COG3839   228 LfvAGF-IGSPPMNLLPGTVEGGGVRLGGVRLPLPAALAAAAGGEVTLGIRPEHL 281

MlaF

COG1127

ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ...

1-217

1.97e-51

ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];

Pssm-ID: 440744 [Multi-domain] Cd Length: 241 Bit Score: 175.17 E-value: 1.97e-51

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   1 MTPRLSLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQAREL- 79
Cdd:COG1127     2 SEPMIEVRNLTKSFGDRVVLDGVSLDVPRGEILAIIGGSGSGKSVLLKLIIGLLRPDSGEILVDGQDITGLSEKELYELr 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  80 -GIAMVHQHFALFDTLSVTENVALGL--STGISAAEIEREIRLLGEKYGLEVD----PAsvvmELSMGERQRVEILRALM 152
Cdd:COG1127    82 rRIGMLFQGGALFDSLTVFENVAFPLreHTDLSEAEIRELVLEKLELVGLPGAadkmPS----ELSGGMRKRVALARALA 157

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2549828669 153 TKPKLLILDEPTSVLTPQAVRKLFKTLHQLSSE-GVSILFISHKLDEIRELADRCVVLRAGKVVAS 217
Cdd:COG1127   158 LDPEILLYDEPTAGLDPITSAVIDELIRELRDElGLTSVVVTHDLDSAFAIADRVAVLADGKIIAE 223

TauB

COG1116

ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion ...

1-219

3.64e-51

ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism];

Pssm-ID: 440733 [Multi-domain] Cd Length: 260 Bit Score: 174.89 E-value: 3.64e-51

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   1 MTPRLSLRNITKRYP----GITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPlgVETPAQA 76
Cdd:COG1116     4 AAPALELRGVSKRFPtgggGVTALDDVSLTVAAGEFVALVGPSGCGKSTLLRLIAGLEKPTSGEVLVDGKP--VTGPGPD 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  77 RelgiAMVHQHFALFDTLSVTENVALGLS-TGISAAEIEREIRLLGEKYGLE--VD--PAsvvmELSMGERQRVEILRAL 151
Cdd:COG1116    82 R----GVVFQEPALLPWLTVLDNVALGLElRGVPKAERRERARELLELVGLAgfEDayPH----QLSGGMRQRVAIARAL 153

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2549828669 152 MTKPKLLILDEPTS---VLTPQAVRKLFKTLHQlsSEGVSILFISHKLDE-IReLADRCVVLRA--GKVVASVD 219
Cdd:COG1116   154 ANDPEVLLMDEPFGaldALTRERLQDELLRLWQ--ETGKTVLFVTHDVDEaVF-LADRVVVLSArpGRIVEEID 224

ABC_MJ0796_LolCDE_FtsE

cd03255

ATP-binding cassette domain of the transporters involved in export of lipoprotein and ...

5-214

3.70e-51

ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.

Pssm-ID: 213222 [Multi-domain] Cd Length: 218 Bit Score: 173.44 E-value: 3.70e-51

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   5 LSLRNITKRYPG----ITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQ----- 75
Cdd:cd03255     1 IELKNLSKTYGGggekVQALKGVSLSIEKGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVRVDGTDISKLSEKElaafr 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  76 ARELGIamVHQHFALFDTLSVTENVALGLS-TGISAAEIEREIRLLGEKYGLEVDPASVVMELSMGERQRVEILRALMTK 154
Cdd:cd03255    81 RRHIGF--VFQSFNLLPDLTALENVELPLLlAGVPKKERRERAEELLERVGLGDRLNHYPSELSGGQQQRVAIARALAND 158

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2549828669 155 PKLLILDEPTSVLTPQAVRKLFKTLHQLSSE-GVSILFISHKlDEIRELADRCVVLRAGKV 214
Cdd:cd03255   159 PKIILADEPTGNLDSETGKEVMELLRELNKEaGTTIVVVTHD-PELAEYADRIIELRDGKI 218

FtsE

COG2884

Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];

5-215

3.90e-51

Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 442130 [Multi-domain] Cd Length: 223 Bit Score: 173.70 E-value: 3.90e-51

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   5 LSLRNITKRYP-GITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGV----ETPAQAREL 79
Cdd:COG2884     2 IRFENVSKRYPgGREALSDVSLEIEKGEFVFLTGPSGAGKSTLLKLLYGEERPTSGQVLVNGQDLSRlkrrEIPYLRRRI 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  80 GIamVHQHFALFDTLSVTENVALGLS-TGISAAEIEREIRLLGEKYGLEVDPASVVMELSMGERQRVEILRALMTKPKLL 158
Cdd:COG2884    82 GV--VFQDFRLLPDRTVYENVALPLRvTGKSRKEIRRRVREVLDLVGLSDKAKALPHELSGGEQQRVAIARALVNRPELL 159

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2549828669 159 ILDEPTSVLTPQAVRKLFKTLHQLSSEGVSILFISHKLDEIRELADRCVVLRAGKVV 215
Cdd:COG2884   160 LADEPTGNLDPETSWEIMELLEEINRRGTTVLIATHDLELVDRMPKRVLELEDGRLV 216

LivF

COG0410

ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid ...

2-222

7.14e-51

ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid transport and metabolism];

Pssm-ID: 440179 [Multi-domain] Cd Length: 236 Bit Score: 173.24 E-value: 7.14e-51

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   2 TPRLSLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQARELGI 81
Cdd:COG0410     1 MPMLEVENLHAGYGGIHVLHGVSLEVEEGEIVALLGRNGAGKTTLLKAISGLLPPRSGSIRFDGEDITGLPPHRIARLGI 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  82 AMVHQHFALFDTLSVTENVALGLSTGISAAEIEREIRL-------LGEKYGlevDPASvvmELSMGERQRVEILRALMTK 154
Cdd:COG0410    81 GYVPEGRRIFPSLTVEENLLLGAYARRDRAEVRADLERvyelfprLKERRR---QRAG---TLSGGEQQMLAIGRALMSR 154

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2549828669 155 PKLLILDEPTSVLTPQAVRKLFKTLHQLSSEGVSILFISHKLDEIRELADRCVVLRAGKVVASVDPKA 222
Cdd:COG0410   155 PKLLLLDEPSLGLAPLIVEEIFEIIRRLNREGVTILLVEQNARFALEIADRAYVLERGRIVLEGTAAE 222

ABC_MetN_methionine_transporter

cd03258

ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ...

5-215

9.18e-50

ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213225 [Multi-domain] Cd Length: 233 Bit Score: 170.45 E-value: 9.18e-50

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   5 LSLRNITKRYPG----ITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQAREL- 79
Cdd:cd03258     2 IELKNVSKVFGDtggkVTALKDVSLSVPKGEIFGIIGRSGAGKSTLIRCINGLERPTSGSVLVDGTDLTLLSGKELRKAr 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  80 -GIAMVHQHFALFDTLSVTENVALGLS-TGISAAEIEREIRLLGEKYGLEVDPASVVMELSMGERQRVEILRALMTKPKL 157
Cdd:cd03258    82 rRIGMIFQHFNLLSSRTVFENVALPLEiAGVPKAEIEERVLELLELVGLEDKADAYPAQLSGGQKQRVGIARALANNPKV 161

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2549828669 158 LILDEPTSVLTPQAVRKLFKTLHQLSSE-GVSILFISHKLDEIRELADRCVVLRAGKVV 215
Cdd:cd03258   162 LLCDEATSALDPETTQSILALLRDINRElGLTIVLITHEMEVVKRICDRVAVMEKGEVV 220

ABC_Org_Solvent_Resistant

cd03261

ATP-binding cassette transport system involved in resistance to organic solvents; ABC ...

5-216

1.02e-49

ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213228 [Multi-domain] Cd Length: 235 Bit Score: 170.38 E-value: 1.02e-49

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   5 LSLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQARELG--IA 82
Cdd:cd03261     1 IELRGLTKSFGGRTVLKGVDLDVRRGEILAIIGPSGSGKSTLLRLIVGLLRPDSGEVLIDGEDISGLSEAELYRLRrrMG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  83 MVHQHFALFDTLSVTENVALGLS--TGISAAEIEREIRLLGEKYGLEVD----PAsvvmELSMGERQRVEILRALMTKPK 156
Cdd:cd03261    81 MLFQSGALFDSLTVFENVAFPLRehTRLSEEEIREIVLEKLEAVGLRGAedlyPA----ELSGGMKKRVALARALALDPE 156

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2549828669 157 LLILDEPTSVLTPQAVRK---LFKTLHQlsSEGVSILFISHKLDEIRELADRCVVLRAGKVVA 216
Cdd:cd03261   157 LLLYDEPTAGLDPIASGViddLIRSLKK--ELGLTSIMVTHDLDTAFAIADRIAVLYDGKIVA 217

ZnuC

COG1121

ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ...

1-231

1.03e-48

ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];

Pssm-ID: 440738 [Multi-domain] Cd Length: 245 Bit Score: 167.96 E-value: 1.03e-48

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   1 MTPRLSLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPlgvetPAQARELg 80
Cdd:COG1121     3 MMPAIELENLTVSYGGRPVLEDVSLTIPPGEFVAIVGPNGAGKSTLLKAILGLLPPTSGTVRLFGKP-----PRRARRR- 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  81 IAMVHQHFAlFDT---LSVTENVALGLSTGI------SAAEIEREIRLLgEKYGLEvDPASV-VMELSMGERQRVEILRA 150
Cdd:COG1121    77 IGYVPQRAE-VDWdfpITVRDVVLMGRYGRRglfrrpSRADREAVDEAL-ERVGLE-DLADRpIGELSGGQQQRVLLARA 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 151 LMTKPKLLILDEPTSVLTPQAVRKLFKTLHQLSSEGVSILFISHKLDEIRELADRCVVLrAGKVVASVDPK-AESEENLA 229
Cdd:COG1121   154 LAQDPDLLLLDEPFAGVDAATEEALYELLRELRREGKTILVVTHDLGAVREYFDRVLLL-NRGLVAHGPPEeVLTPENLS 232


                  ..
gi 2549828669 230 RL 231
Cdd:COG1121   233 RA 234

ABC_NikE_OppD_transporters

cd03257

ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ...

5-215

2.24e-48

ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.

Pssm-ID: 213224 [Multi-domain] Cd Length: 228 Bit Score: 166.53 E-value: 2.24e-48

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   5 LSLRNITKRYPG----ITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQARELG 80
Cdd:cd03257     2 LEVKNLSVSFPTgggsVKALDDVSFSIKKGETLGLVGESGSGKSTLARAILGLLKPTSGSIIFDGKDLLKLSRRLRKIRR 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  81 --IAMVHQH--FALFDTLSVTENVA--LGLSTGISAAEIEREIRLLGEKyglEVDPASVVM-----ELSMGERQRVEILR 149
Cdd:cd03257    82 keIQMVFQDpmSSLNPRMTIGEQIAepLRIHGKLSKKEARKEAVLLLLV---GVGLPEEVLnryphELSGGQRQRVAIAR 158

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2549828669 150 ALMTKPKLLILDEPTS---VLTPQAVRKLFKTLHQlsSEGVSILFISHKLDEIRELADRCVVLRAGKVV 215
Cdd:cd03257   159 ALALNPKLLIADEPTSaldVSVQAQILDLLKKLQE--ELGLTLLFITHDLGVVAKIADRVAVMYAGKIV 225

ABC_Class3

cd03229

ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ...

5-213

3.29e-48

ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213196 [Multi-domain] Cd Length: 178 Bit Score: 164.28 E-value: 3.29e-48

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   5 LSLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPL---GVETPAQARELGi 81
Cdd:cd03229     1 LELKNVSKRYGQKTVLNDVSLNIEAGEIVALLGPSGSGKSTLLRCIAGLEEPDSGSILIDGEDLtdlEDELPPLRRRIG- 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  82 aMVHQHFALFDTLSVTENVALGLSTgisaaeiereirllgekyglevdpasvvmelsmGERQRVEILRALMTKPKLLILD 161
Cdd:cd03229    80 -MVFQDFALFPHLTVLENIALGLSG---------------------------------GQQQRVALARALAMDPDVLLLD 125

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2549828669 162 EPTSVLTPQA---VRKLFKTLHQLSseGVSILFISHKLDEIRELADRCVVLRAGK 213
Cdd:cd03229   126 EPTSALDPITrreVRALLKSLQAQL--GITVVLVTHDLDEAARLADRVVVLRDGK 178

ABC_PhnC_transporter

cd03256

ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ...

5-231

6.20e-48

ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213223 [Multi-domain] Cd Length: 241 Bit Score: 165.82 E-value: 6.20e-48

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   5 LSLRNITKRYP-GITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQAREL--GI 81
Cdd:cd03256     1 IEVENLSKTYPnGKKALKDVSLSINPGEFVALIGPSGAGKSTLLRCLNGLVEPTSGSVLIDGTDINKLKGKALRQLrrQI 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  82 AMVHQHFALFDTLSVTENVALG----------LSTGISAAEIEREIRLLgEKYGLEVDPASVVMELSMGERQRVEILRAL 151
Cdd:cd03256    81 GMIFQQFNLIERLSVLENVLSGrlgrrstwrsLFGLFPKEEKQRALAAL-ERVGLLDKAYQRADQLSGGQQQRVAIARAL 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 152 MTKPKLLILDEPTSVLTPQAVRKLFKTLHQLSSE-GVSILFISHKLDEIRELADRCVVLRAGKVVASVDPKAESEENLAR 230
Cdd:cd03256   160 MQQPKLILADEPVASLDPASSRQVMDLLKRINREeGITVIVSLHQVDLAREYADRIVGLKDGRIVFDGPPAELTDEVLDE 239


                  .
gi 2549828669 231 L 231
Cdd:cd03256   240 I 240

AbcC

COG1135

ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];

5-217

4.65e-47

ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];

Pssm-ID: 440750 [Multi-domain] Cd Length: 339 Bit Score: 166.41 E-value: 4.65e-47

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   5 LSLRNITKRYPG----ITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQAREL- 79
Cdd:COG1135     2 IELENLSKTFPTkggpVTALDDVSLTIEKGEIFGIIGYSGAGKSTLIRCINLLERPTSGSVLVDGVDLTALSERELRAAr 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  80 -GIAMVHQHFALFDTLSVTENVALGLS-TGISAAEIEREIRLLGEKYGLEvD-----PAsvvmELSMGERQRVEILRALM 152
Cdd:COG1135    82 rKIGMIFQHFNLLSSRTVAENVALPLEiAGVPKAEIRKRVAELLELVGLS-DkadayPS----QLSGGQKQRVGIARALA 156

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2549828669 153 TKPKLLILDEPTSVLTPQ---AVRKLFKTLHQ-LsseGVSILFISHKLDEIRELADRCVVLRAGKVVAS 217
Cdd:COG1135   157 NNPKVLLCDEATSALDPEttrSILDLLKDINReL---GLTIVLITHEMDVVRRICDRVAVLENGRIVEQ 222

ABC_BcrA_bacitracin_resist

cd03268

ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily ...

5-217

6.86e-47

ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.

Pssm-ID: 213235 [Multi-domain] Cd Length: 208 Bit Score: 162.00 E-value: 6.86e-47

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   5 LSLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQAReLGiAMV 84
Cdd:cd03268     1 LKTNDLTKTYGKKRVLDDISLHVKKGEIYGFLGPNGAGKTTTMKIILGLIKPDSGEITFDGKSYQKNIEALRR-IG-ALI 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  85 HQHfALFDTLSVTENV-ALGLSTGISAAEIEREIRLLGekygLEVDPASVVMELSMGERQRVEILRALMTKPKLLILDEP 163
Cdd:cd03268    79 EAP-GFYPNLTARENLrLLARLLGIRKKRIDEVLDVVG----LKDSAKKKVKGFSLGMKQRLGIALALLGNPDLLILDEP 153

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2549828669 164 TSVLTPQAVRKLFKTLHQLSSEGVSILFISHKLDEIRELADRCVVLRAGKVVAS 217
Cdd:cd03268   154 TNGLDPDGIKELRELILSLRDQGITVLISSHLLSEIQKVADRIGIINKGKLIEE 207

ABC_HisP_GlnQ

cd03262

ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ...

5-214

7.01e-47

ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.

Pssm-ID: 213229 [Multi-domain] Cd Length: 213 Bit Score: 161.93 E-value: 7.01e-47

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   5 LSLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGvETPAQAREL--GIA 82
Cdd:cd03262     1 IEIKNLHKSFGDFHVLKGIDLTVKKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTIIIDGLKLT-DDKKNINELrqKVG 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  83 MVHQHFALFDTLSVTENVALGLST--GISAAEIEREIRLLGEKYGLEVDPASVVMELSMGERQRVEILRALMTKPKLLIL 160
Cdd:cd03262    80 MVFQQFNLFPHLTVLENITLAPIKvkGMSKAEAEERALELLEKVGLADKADAYPAQLSGGQQQRVAIARALAMNPKVMLF 159

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2549828669 161 DEPTSVLTPQAVRKLFKTLHQLSSEGVSILFISHKLDEIRELADRCVVLRAGKV 214
Cdd:cd03262   160 DEPTSALDPELVGEVLDVMKDLAEEGMTMVVVTHEMGFAREVADRVIFMDDGRI 213

ABC_ATPase

cd00267

ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ...

6-213

7.80e-47

ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213179 [Multi-domain] Cd Length: 157 Bit Score: 160.10 E-value: 7.80e-47

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   6 SLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQARElGIAMVH 85
Cdd:cd00267     1 EIENLSFRYGGRTALDNVSLTLKAGEIVALVGPNGSGKSTLLRAIAGLLKPTSGEILIDGKDIAKLPLEELRR-RIGYVP 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  86 QhfalfdtlsvtenvalglstgisaaeiereirllgekyglevdpasvvmeLSMGERQRVEILRALMTKPKLLILDEPTS 165
Cdd:cd00267    80 Q--------------------------------------------------LSGGQRQRVALARALLLNPDLLLLDEPTS 109

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 2549828669 166 VLTPQAVRKLFKTLHQLSSEGVSILFISHKLDEIRELADRCVVLRAGK 213
Cdd:cd00267   110 GLDPASRERLLELLRELAEEGRTVIIVTHDPELAELAADRVIVLKDGK 157

ABC_CysA_sulfate_importer

cd03296

ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ...

8-214

1.10e-46

ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213263 [Multi-domain] Cd Length: 239 Bit Score: 162.51 E-value: 1.10e-46

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   8 RNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGvETPAQARELGiaMVHQH 87
Cdd:cd03296     6 RNVSKRFGDFVALDDVSLDIPSGELVALLGPSGSGKTTLLRLIAGLERPDSGTILFGGEDAT-DVPVQERNVG--FVFQH 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  88 FALFDTLSVTENVALGL-----STGISAAEIEREIRLLGEKYGLEVDPASVVMELSMGERQRVEILRALMTKPKLLILDE 162
Cdd:cd03296    83 YALFRHMTVFDNVAFGLrvkprSERPPEAEIRAKVHELLKLVQLDWLADRYPAQLSGGQRQRVALARALAVEPKVLLLDE 162

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2549828669 163 PTSVLTPQAVRKLFKTLHQLSSE-GVSILFISHKLDEIRELADRCVVLRAGKV 214
Cdd:cd03296   163 PFGALDAKVRKELRRWLRRLHDElHVTTVFVTHDQEEALEVADRVVVMNKGRI 215

YhaQ

COG4152

ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...

5-217

3.69e-46

ABC-type uncharacterized transport system, ATPase component [General function prediction only];

Pssm-ID: 443322 [Multi-domain] Cd Length: 298 Bit Score: 162.97 E-value: 3.69e-46

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   5 LSLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQ------ARe 78
Cdd:COG4152     2 LELKGLTKRFGDKTAVDDVSFTVPKGEIFGLLGPNGAGKTTTIRIILGILAPDSGEVLWDGEPLDPEDRRRigylpeER- 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  79 lgiamvhqhfALFDTLSVTEN-VALGLSTGISAAEIEREIRLLGEKYGLEVDPASVVMELSMGERQRVEILRALMTKPKL 157
Cdd:COG4152    81 ----------GLYPKMKVGEQlVYLARLKGLSKAEAKRRADEWLERLGLGDRANKKVEELSKGNQQKVQLIAALLHDPEL 150

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 158 LILDEPTSVLTPQAVRKLFKTLHQLSSEGVSILFISHKLDEIRELADRCVVLRAGKVVAS 217
Cdd:COG4152   151 LILDEPFSGLDPVNVELLKDVIRELAAKGTTVIFSSHQMELVEELCDRIVIINKGRKVLS 210

ABC_putative_ATPase

cd03269

ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ...

5-216

3.95e-46

ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213236 [Multi-domain] Cd Length: 210 Bit Score: 160.14 E-value: 3.95e-46

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   5 LSLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETpaqarELGIAMV 84
Cdd:cd03269     1 LEVENVTKRFGRVTALDDISFSVEKGEIFGLLGPNGAGKTTTIRMILGIILPDSGEVLFDGKPLDIAA-----RNRIGYL 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  85 HQHFALFDTLSVTEN-VALGLSTGISAAEIEREIRLLGEKYGLEVDPASVVMELSMGERQRVEILRALMTKPKLLILDEP 163
Cdd:cd03269    76 PEERGLYPKMKVIDQlVYLAQLKGLKKEEARRRIDEWLERLELSEYANKRVEELSKGNQQKVQFIAAVIHDPELLILDEP 155

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2549828669 164 TSVLTPQAVRKLFKTLHQLSSEGVSILFISHKLDEIRELADRCVVLRAGKVVA 216
Cdd:cd03269   156 FSGLDPVNVELLKDVIRELARAGKTVILSTHQMELVEELCDRVLLLNKGRAVL 208

GlnQ

COG1126

ABC-type polar amino acid transport system, ATPase component [Amino acid transport and ...

5-221

1.46e-45

ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism];

Pssm-ID: 440743 [Multi-domain] Cd Length: 239 Bit Score: 159.39 E-value: 1.46e-45

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   5 LSLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGvETPAQAREL--GIA 82
Cdd:COG1126     2 IEIENLHKSFGDLEVLKGISLDVEKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTITVDGEDLT-DSKKDINKLrrKVG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  83 MVHQHFALFDTLSVTENVALGLST--GISAAEIEREIRLLGEKYGL----EVDPAsvvmELSMGERQRVEILRALMTKPK 156
Cdd:COG1126    81 MVFQQFNLFPHLTVLENVTLAPIKvkKMSKAEAEERAMELLERVGLadkaDAYPA----QLSGGQQQRVAIARALAMEPK 156

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2549828669 157 LLILDEPTSVLTPQAVRKLFKTLHQLSSEGVSILFISHKLDEIRELADRCVVLRAGKVVASVDPK 221
Cdd:COG1126   157 VMLFDEPTSALDPELVGEVLDVMRDLAKEGMTMVVVTHEMGFAREVADRVVFMDGGRIVEEGPPE 221

ABC_tran

pfam00005

ABC transporter; ABC transporters for a large family of proteins responsible for translocation ...

21-165

3.07e-45

Pssm-ID: 394964 [Multi-domain] Cd Length: 150 Bit Score: 155.50 E-value: 3.07e-45

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  21 DHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQARElGIAMVHQHFALFDTLSVTENV 100
Cdd:pfam00005   2 KNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQDLTDDERKSLRK-EIGYVFQDPQLFPRLTVRENL 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 101 ALGLS-TGISAAEIEREIRLLGEKYGLEVDPASVVM----ELSMGERQRVEILRALMTKPKLLILDEPTS 165
Cdd:pfam00005  81 RLGLLlKGLSKREKDARAEEALEKLGLGDLADRPVGerpgTLSGGQRQRVAIARALLTKPKLLLLDEPTA 150

FepC

COG1120

ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ...

4-231

3.93e-45

ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];

Pssm-ID: 440737 [Multi-domain] Cd Length: 254 Bit Score: 158.67 E-value: 3.93e-45

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   4 RLSLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQ-ARElgIA 82
Cdd:COG1120     1 MLEAENLSVGYGGRPVLDDVSLSLPPGEVTALLGPNGSGKSTLLRALAGLLKPSSGEVLLDGRDLASLSRRElARR--IA 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  83 MVHQHFALFDTLSVTENVALGLSTGISA---------AEIEREIRLLG-----EKYglevdpasvVMELSMGERQRVEIL 148
Cdd:COG1120    79 YVPQEPPAPFGLTVRELVALGRYPHLGLfgrpsaedrEAVEEALERTGlehlaDRP---------VDELSGGERQRVLIA 149

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 149 RALMTKPKLLILDEPTSVLTPQAVRKLFKTLHQLSSE-GVSILFISHKLDEIRELADRCVVLRAGKVVASVDPkAE--SE 225
Cdd:COG1120   150 RALAQEPPLLLLDEPTSHLDLAHQLEVLELLRRLARErGRTVVMVLHDLNLAARYADRLVLLKDGRIVAQGPP-EEvlTP 228


                  ....*.
gi 2549828669 226 ENLARL 231
Cdd:COG1120   229 ELLEEV 234

ABC_PotA_N

cd03300

ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ...

5-215

5.44e-45

ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213267 [Multi-domain] Cd Length: 232 Bit Score: 157.78 E-value: 5.44e-45

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   5 LSLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLgVETPAQARelGIAMV 84
Cdd:cd03300     1 IELENVSKFYGGFVALDGVSLDIKEGEFFTLLGPSGCGKTTLLRLIAGFETPTSGEILLDGKDI-TNLPPHKR--PVNTV 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  85 HQHFALFDTLSVTENVALGLST-GISAAEIEREIRLLGEKYGLEVDPASVVMELSMGERQRVEILRALMTKPKLLILDEP 163
Cdd:cd03300    78 FQNYALFPHLTVFENIAFGLRLkKLPKAEIKERVAEALDLVQLEGYANRKPSQLSGGQQQRVAIARALVNEPKVLLLDEP 157

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2549828669 164 TSVLTPQAVRKL---FKTLHQlsSEGVSILFISHKLDEIRELADRCVVLRAGKVV 215
Cdd:cd03300   158 LGALDLKLRKDMqleLKRLQK--ELGITFVFVTHDQEEALTMSDRIAVMNKGKIQ 210

SunT

COG2274

ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ...

1-217

7.34e-45

ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];

Pssm-ID: 441875 [Multi-domain] Cd Length: 711 Bit Score: 167.70 E-value: 7.34e-45

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   1 MTPRLSLRNITKRYPGITAN--DHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQARE 78
Cdd:COG2274   470 LKGDIELENVSFRYPGDSPPvlDNISLTIKPGERVAIVGRSGSGKSTLLKLLLGLYEPTSGRILIDGIDLRQIDPASLRR 549

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  79 LgIAMVHQHFALFDTlSVTENVALGlSTGISAAEIEREIRLLG-----EK--YGLEvdpaSVVME----LSMGERQRVEI 147
Cdd:COG2274   550 Q-IGVVLQDVFLFSG-TIRENITLG-DPDATDEEIIEAARLAGlhdfiEAlpMGYD----TVVGEggsnLSGGQRQRLAI 622

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 148 LRALMTKPKLLILDEPTSVLTPQAVRKLFKTLHQLsSEGVSILFISHKLDEIReLADRCVVLRAGKVVAS 217
Cdd:COG2274   623 ARALLRNPRILILDEATSALDAETEAIILENLRRL-LKGRTVIIIAHRLSTIR-LADRIIVLDKGRIVED 690

ABC_subfamily_A

cd03263

ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ...

5-217

1.72e-44

ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.

Pssm-ID: 213230 [Multi-domain] Cd Length: 220 Bit Score: 156.13 E-value: 1.72e-44

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   5 LSLRNITKRYPGI--TANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQARELGIA 82
Cdd:cd03263     1 LQIRNLTKTYKKGtkPAVDDLSLNVYKGEIFGLLGHNGAGKTTTLKMLTGELRPTSGTAYINGYSIRTDRKAARQSLGYC 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  83 MvhQHFALFDTLSVTENVAL-GLSTGISAAEIEREIRLLGEKYGLEVDPASVVMELSMGERQRVEILRALMTKPKLLILD 161
Cdd:cd03263    81 P--QFDALFDELTVREHLRFyARLKGLPKSEIKEEVELLLRVLGLTDKANKRARTLSGGMKRKLSLAIALIGGPSVLLLD 158

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2549828669 162 EPTSVLTPQAVRKLFKTLHQLSSeGVSILFISHKLDEIRELADRCVVLRAGKVVAS 217
Cdd:cd03263   159 EPTSGLDPASRRAIWDLILEVRK-GRSIILTTHSMDEAEALCDRIAIMSDGKLRCI 213

ABCC_MRP_Like

cd03228

ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ...

5-213

1.25e-43

ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213195 [Multi-domain] Cd Length: 171 Bit Score: 151.77 E-value: 1.25e-43

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   5 LSLRNITKRYPGITAN--DHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQARELgIA 82
Cdd:cd03228     1 IEFKNVSFSYPGRPKPvlKDVSLTIKPGEKVAIVGPSGSGKSTLLKLLLRLYDPTSGEILIDGVDLRDLDLESLRKN-IA 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  83 MVHQHFALFDTlSVTENValglstgisaaeiereirllgekyglevdpasvvmeLSMGERQRVEILRALMTKPKLLILDE 162
Cdd:cd03228    80 YVPQDPFLFSG-TIRENI------------------------------------LSGGQRQRIAIARALLRDPPILILDE 122

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2549828669 163 PTSVLTPQAVRKLFKTLHQLsSEGVSILFISHKLDEIReLADRCVVLRAGK 213
Cdd:cd03228   123 ATSALDPETEALILEALRAL-AKGKTVIVIAHRLSTIR-DADRIIVLDDGR 171

FetA

COG4619

ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];

5-214

1.82e-43

ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];

Pssm-ID: 443661 [Multi-domain] Cd Length: 209 Bit Score: 152.66 E-value: 1.82e-43

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   5 LSLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQARELgIAMV 84
Cdd:COG4619     1 LELEGLSFRVGGKPILSPVSLTLEAGECVAITGPSGSGKSTLLRALADLDPPTSGEIYLDGKPLSAMPPPEWRRQ-VAYV 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  85 HQHFALFDTlSVTENVALGLSTGISAAEIEREIRLLgEKYGLevdPASV----VMELSMGERQRVEILRALMTKPKLLIL 160
Cdd:COG4619    80 PQEPALWGG-TVRDNLPFPFQLRERKFDRERALELL-ERLGL---PPDIldkpVERLSGGERQRLALIRALLLQPDVLLL 154

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2549828669 161 DEPTSVLTPQAVRKLFKTLHQLS-SEGVSILFISHKLDEIRELADRCVVLRAGKV 214
Cdd:COG4619   155 DEPTSALDPENTRRVEELLREYLaEEGRAVLWVSHDPEQIERVADRVLTLEAGRL 209

ABC_YhbG

cd03218

ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ...

5-220

8.23e-43

ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.

Pssm-ID: 213185 [Multi-domain] Cd Length: 232 Bit Score: 151.93 E-value: 8.23e-43

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   5 LSLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQARELGIAMV 84
Cdd:cd03218     1 LRAENLSKRYGKRKVVNGVSLSVKQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGKILLDGQDITKLPMHKRARLGIGYL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  85 HQHFALFDTLSVTENVALGL-STGISAAEIEREIRLLGEKYGLEVDPASVVMELSMGERQRVEILRALMTKPKLLILDEP 163
Cdd:cd03218    81 PQEASIFRKLTVEENILAVLeIRGLSKKEREEKLEELLEEFHITHLRKSKASSLSGGERRRVEIARALATNPKFLLLDEP 160

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2549828669 164 TSVLTPQAVRKLFKTLHQLSSEGVSILFISHKLDEIRELADRCVVLRAGKVVASVDP 220
Cdd:cd03218   161 FAGVDPIAVQDIQKIIKILKDRGIGVLITDHNVRETLSITDRAYIIYEGKVLAEGTP 217

metN

PRK11153

DL-methionine transporter ATP-binding subunit; Provisional

7-215

8.71e-43

DL-methionine transporter ATP-binding subunit; Provisional

Pssm-ID: 236863 [Multi-domain] Cd Length: 343 Bit Score: 154.96 E-value: 8.71e-43

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   7 LRNITKRYPG----ITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQAREL--G 80
Cdd:PRK11153    4 LKNISKVFPQggrtIHALNNVSLHIPAGEIFGVIGASGAGKSTLIRCINLLERPTSGRVLVDGQDLTALSEKELRKArrQ 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  81 IAMVHQHFALFDTLSVTENVALGLS-TGISAAEIEREIRLLGEKYGLE----VDPAsvvmELSMGERQRVEILRALMTKP 155
Cdd:PRK11153   84 IGMIFQHFNLLSSRTVFDNVALPLElAGTPKAEIKARVTELLELVGLSdkadRYPA----QLSGGQKQRVAIARALASNP 159

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2549828669 156 KLLILDEPTSVLTPQAVRKLFKTLHQLSSE-GVSILFISHKLDEIRELADRCVVLRAGKVV 215
Cdd:PRK11153  160 KVLLCDEATSALDPATTRSILELLKDINRElGLTIVLITHEMDVVKRICDRVAVIDAGRLV 220

FtsE

TIGR02673

cell division ATP-binding protein FtsE; This model describes FtsE, a member of the ABC ...

7-213

1.33e-42

cell division ATP-binding protein FtsE; This model describes FtsE, a member of the ABC transporter ATP-binding protein family. This protein, and its permease partner FtsX, localize to the division site. In a number of species, the ftsEX gene pair is located next to FtsY, the signal recognition particle-docking protein. [Cellular processes, Cell division]

Pssm-ID: 131721 [Multi-domain] Cd Length: 214 Bit Score: 150.86 E-value: 1.33e-42

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   7 LRNITKRYP-GITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPL----GVETPAQARELGI 81
Cdd:TIGR02673   4 FHNVSKAYPgGVAALHDVSLHIRKGEFLFLTGPSGAGKTTLLKLLYGALTPSRGQVRIAGEDVnrlrGRQLPLLRRRIGV 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  82 amVHQHFALFDTLSVTENVALGLST-GISAAEIEREIRLLGEKYGLEVDPASVVMELSMGERQRVEILRALMTKPKLLIL 160
Cdd:TIGR02673  84 --VFQDFRLLPDRTVYENVALPLEVrGKKEREIQRRVGAALRQVGLEHKADAFPEQLSGGEQQRVAIARAIVNSPPLLLA 161

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2549828669 161 DEPTSVLTPQAVRKLFKTLHQLSSEGVSILFISHKLDEIRELADRCVVLRAGK 213
Cdd:TIGR02673 162 DEPTGNLDPDLSERILDLLKRLNKRGTTVIVATHDLSLVDRVAHRVIILDDGR 214

DppF

COG1124

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...

5-222

1.51e-42

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];

Pssm-ID: 440741 [Multi-domain] Cd Length: 248 Bit Score: 151.49 E-value: 1.51e-42

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   5 LSLRNITKRYP----GITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQARElG 80
Cdd:COG1124     2 LEVRNLSVSYGqggrRVPVLKDVSLEVAPGESFGLVGESGSGKSTLLRALAGLERPWSGEVTFDGRPVTRRRRKAFRR-R 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  81 IAMVHQH-FALFD-TLSVTENVALGL-STGIsaAEIEREIRLLGEKYGLEVD-----PAsvvmELSMGERQRVEILRALM 152
Cdd:COG1124    81 VQMVFQDpYASLHpRHTVDRILAEPLrIHGL--PDREERIAELLEQVGLPPSfldryPH----QLSGGQRQRVAIARALI 154

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2549828669 153 TKPKLLILDEPTSVLTP--QA-VRKLFKTLHQlsSEGVSILFISHKLDEIRELADRCVVLRAGKVVASVDPKA 222
Cdd:COG1124   155 LEPELLLLDEPTSALDVsvQAeILNLLKDLRE--ERGLTYLFVSHDLAVVAHLCDRVAVMQNGRIVEELTVAD 225

DppD

COG0444

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...

5-219

2.71e-42

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];

Pssm-ID: 440213 [Multi-domain] Cd Length: 320 Bit Score: 153.29 E-value: 2.71e-42

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   5 LSLRNITKRYPG----ITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARP---DEGEISFDGHPLGVETPAQAR 77
Cdd:COG0444     2 LEVRNLKVYFPTrrgvVKAVDGVSFDVRRGETLGLVGESGSGKSTLARAILGLLPPpgiTSGEILFDGEDLLKLSEKELR 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  78 EL---GIAMVHQhfalfDTLS-----------VTEnvALGLSTGISAAEIEREIRLLGEKYGLEvDPASVVM----ELSM 139
Cdd:COG0444    82 KIrgrEIQMIFQ-----DPMTslnpvmtvgdqIAE--PLRIHGGLSKAEARERAIELLERVGLP-DPERRLDryphELSG 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 140 GERQRVEILRALMTKPKLLILDEPTSVL--TPQA-VRKLFKTLHQlsSEGVSILFISHKLDEIRELADRCVVLRAGKVV- 215
Cdd:COG0444   154 GMRQRVMIARALALEPKLLIADEPTTALdvTIQAqILNLLKDLQR--ELGLAILFITHDLGVVAEIADRVAVMYAGRIVe 231


                  ....*
gi 2549828669 216 -ASVD 219
Cdd:COG0444   232 eGPVE 236

ABC_MalK_N

cd03301

The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ...

5-215

4.71e-42

The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.

Pssm-ID: 213268 [Multi-domain] Cd Length: 213 Bit Score: 149.33 E-value: 4.71e-42

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   5 LSLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHplgVETPAQARELGIAMV 84
Cdd:cd03301     1 VELENVTKRFGNVTALDDLNLDIADGEFVVLLGPSGCGKTTTLRMIAGLEEPTSGRIYIGGR---DVTDLPPKDRDIAMV 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  85 HQHFALFDTLSVTENVALGL-STGISAAEIEREIRLLGEKYGLEVDPASVVMELSMGERQRVEILRALMTKPKLLILDEP 163
Cdd:cd03301    78 FQNYALYPHMTVYDNIAFGLkLRKVPKDEIDERVREVAELLQIEHLLDRKPKQLSGGQRQRVALGRAIVREPKVFLMDEP 157

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2549828669 164 TSVLTPQ---AVRKLFKTLHQLssEGVSILFISHKLDEIRELADRCVVLRAGKVV 215
Cdd:cd03301   158 LSNLDAKlrvQMRAELKRLQQR--LGTTTIYVTHDQVEAMTMADRIAVMNDGQIQ 210

ABC_phnC

TIGR02315

phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of ...

5-215

1.13e-41

phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of phosphorus-containing organic compound with a stable direct C-P bond rather than a C-O-P linkage. A number of bacterial species have operons, typically about 14 genes in size, with genes for ATP-dependent transport of phosphonates, degradation, and regulation of the expression of the system. Members of this protein family are the ATP-binding cassette component of tripartite ABC transporters of phosphonates. [Transport and binding proteins, Anions]

Pssm-ID: 131368 [Multi-domain] Cd Length: 243 Bit Score: 149.37 E-value: 1.13e-41

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   5 LSLRNITKRYP-GITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQAREL--GI 81
Cdd:TIGR02315   2 LEVENLSKVYPnGKQALKNINLNINPGEFVAIIGPSGAGKSTLLRCINRLVEPSSGSILLEGTDITKLRGKKLRKLrrRI 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  82 AMVHQHFALFDTLSVTENV---ALGLSTGI-------SAAEIEREIRLLgEKYGLEVDPASVVMELSMGERQRVEILRAL 151
Cdd:TIGR02315  82 GMIFQHYNLIERLTVLENVlhgRLGYKPTWrsllgrfSEEDKERALSAL-ERVGLADKAYQRADQLSGGQQQRVAIARAL 160

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2549828669 152 MTKPKLLILDEPTSVLTPQAVRKLFKTLHQLSSE-GVSILFISHKLDEIRELADRCVVLRAGKVV 215
Cdd:TIGR02315 161 AQQPDLILADEPIASLDPKTSKQVMDYLKRINKEdGITVIINLHQVDLAKKYADRIVGLKAGEIV 225

ABC_Pro_Gly_Betaine

cd03294

ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This ...

19-215

1.47e-41

ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This family comprises the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporters is the obligatory coupling of ATP hydrolysis to substrate translocation. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213261 [Multi-domain] Cd Length: 269 Bit Score: 149.72 E-value: 1.47e-41

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  19 ANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQAREL---GIAMVHQHFALFDTLS 95
Cdd:cd03294    39 GVNDVSLDVREGEIFVIMGLSGSGKSTLLRCINRLIEPTSGKVLIDGQDIAAMSRKELRELrrkKISMVFQSFALLPHRT 118

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  96 VTENVALGLS-TGISAAE-IEREIRLLgEKYGLEVDPASVVMELSMGERQRVEILRALMTKPKLLILDEPTSVLTPQAVR 173
Cdd:cd03294   119 VLENVAFGLEvQGVPRAErEERAAEAL-ELVGLEGWEHKYPDELSGGMQQRVGLARALAVDPDILLMDEAFSALDPLIRR 197

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 2549828669 174 KLFKTLHQLSSE-GVSILFISHKLDEIRELADRCVVLRAGKVV 215
Cdd:cd03294   198 EMQDELLRLQAElQKTIVFITHDLDEALRLGDRIAIMKDGRLV 240

ABC_NatA_sodium_exporter

cd03266

ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ...

5-217

3.08e-41

ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.

Pssm-ID: 213233 [Multi-domain] Cd Length: 218 Bit Score: 147.13 E-value: 3.08e-41

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   5 LSLRNITKRY----PGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLgVETPAQAReLG 80
Cdd:cd03266     2 ITADALTKRFrdvkKTVQAVDGVSFTVKPGEVTGLLGPNGAGKTTTLRMLAGLLEPDAGFATVDGFDV-VKEPAEAR-RR 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  81 IAMVHQHFALFDTLSVTENVA-LGLSTGISAAEIEREIRLLGEKYGLEVDPASVVMELSMGERQRVEILRALMTKPKLLI 159
Cdd:cd03266    80 LGFVSDSTGLYDRLTARENLEyFAGLYGLKGDELTARLEELADRLGMEELLDRRVGGFSTGMRQKVAIARALVHDPPVLL 159

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2549828669 160 LDEPTSVLTPQAVRKLFKTLHQLSSEGVSILFISHKLDEIRELADRCVVLRAGKVVAS 217
Cdd:cd03266   160 LDEPTTGLDVMATRALREFIRQLRALGKCILFSTHIMQEVERLCDRVVVLHRGRVVYE 217

ABC_Metallic_Cations

cd03235

ATP-binding cassette domain of the metal-type transporters; This family includes transporters ...

6-217

9.78e-41

ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.

Pssm-ID: 213202 [Multi-domain] Cd Length: 213 Bit Score: 145.75 E-value: 9.78e-41

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   6 SLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPlgvetPAQARELgIAMVH 85
Cdd:cd03235     1 EVEDLTVSYGGHPVLEDVSFEVKPGEFLAIVGPNGAGKSTLLKAILGLLKPTSGSIRVFGKP-----LEKERKR-IGYVP 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  86 QHFaLFDT---LSVTENVALGL------STGISAAEIEREIRLLgEKYGLEVDPASVVMELSMGERQRVEILRALMTKPK 156
Cdd:cd03235    75 QRR-SIDRdfpISVRDVVLMGLyghkglFRRLSKADKAKVDEAL-ERVGLSELADRQIGELSGGQQQRVLLARALVQDPD 152

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2549828669 157 LLILDEPTSVLTPQAVRKLFKTLHQLSSEGVSILFISHKLDEIRELADRCVVLrAGKVVAS 217
Cdd:cd03235   153 LLLLDEPFAGVDPKTQEDIYELLRELRREGMTILVVTHDLGLVLEYFDRVLLL-NRTVVAS 212

CydD

COG4988

ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease ...

3-227

2.35e-40

ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];

Pssm-ID: 444012 [Multi-domain] Cd Length: 563 Bit Score: 152.99 E-value: 2.35e-40

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   3 PRLSLRNITKRYP-GITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQARELgI 81
Cdd:COG4988   335 PSIELEDVSFSYPgGRPALDGLSLTIPPGERVALVGPSGAGKSTLLNLLLGFLPPYSGSILINGVDLSDLDPASWRRQ-I 413

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  82 AMVHQHFALFDTlSVTENVALGlSTGISAAEIEREIR---LLGEKYGLEVDPASVVME----LSMGERQRVEILRALMTK 154
Cdd:COG4988   414 AWVPQNPYLFAG-TIRENLRLG-RPDASDEELEAALEaagLDEFVAALPDGLDTPLGEggrgLSGGQAQRLALARALLRD 491

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2549828669 155 PKLLILDEPTSVLTPQAVRKLFKTLHQLsSEGVSILFISHKLDEIRElADRCVVLRAGKVVASVDPKAESEEN 227
Cdd:COG4988   492 APLLLLDEPTAHLDAETEAEILQALRRL-AKGRTVILITHRLALLAQ-ADRILVLDDGRIVEQGTHEELLAKN 562

ThiQ

COG3840

ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];

5-241

3.57e-40

ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];

Pssm-ID: 443051 [Multi-domain] Cd Length: 232 Bit Score: 144.90 E-value: 3.57e-40

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   5 LSLRNITKRYPGITAndHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQaRelGIAMV 84
Cdd:COG3840     2 LRLDDLTYRYGDFPL--RFDLTIAAGERVAILGPSGAGKSTLLNLIAGFLPPDSGRILWNGQDLTALPPAE-R--PVSML 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  85 HQHFALFDTLSVTENVALGLSTG--ISAAEIEREIRLLgEKYGLE--VD--PAsvvmELSMGERQRVEILRALMTKPKLL 158
Cdd:COG3840    77 FQENNLFPHLTVAQNIGLGLRPGlkLTAEQRAQVEQAL-ERVGLAglLDrlPG----QLSGGQRQRVALARCLVRKRPIL 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 159 ILDEPTSVLTPqAVRK----LFKTLHQlsSEGVSILFISHKLDEIRELADRCVVLRAGKVVASVDPkaeseenlARLMIG 234
Cdd:COG3840   152 LLDEPFSALDP-ALRQemldLVDELCR--ERGLTVLMVTHDPEDAARIADRVLLVADGRIAADGPT--------AALLDG 220


                  ....*..
gi 2549828669 235 NDPPTVR 241
Cdd:COG3840   221 EPPPALA 227

ABC_ModC_like

cd03299

ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely ...

23-221

5.55e-40

ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely related to ModC. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213266 [Multi-domain] Cd Length: 235 Bit Score: 144.40 E-value: 5.55e-40

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  23 VSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLgveTPAQARELGIAMVHQHFALFDTLSVTENVAL 102
Cdd:cd03299    18 VSLEVERGDYFVILGPTGSGKSVLLETIAGFIKPDSGKILLNGKDI---TNLPPEKRDISYVPQNYALFPHMTVYKNIAY 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 103 GLST-GISAAEIEREIRLLGEKYG----LEVDPASvvmeLSMGERQRVEILRALMTKPKLLILDEPTSVLTPQ---AVRK 174
Cdd:cd03299    95 GLKKrKVDKKEIERKVLEIAEMLGidhlLNRKPET----LSGGEQQRVAIARALVVNPKILLLDEPFSALDVRtkeKLRE 170

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 2549828669 175 LFKTLHQLSseGVSILFISHKLDEIRELADRCVVLRAGKVVASVDPK 221
Cdd:cd03299   171 ELKKIRKEF--GVTVLHVTHDFEEAWALADKVAIMLNGKLIQVGKPE 215

CcmA

COG4133

ABC-type transport system involved in cytochrome c biogenesis, ATPase component ...

3-213

7.43e-40

ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];

Pssm-ID: 443308 [Multi-domain] Cd Length: 206 Bit Score: 143.00 E-value: 7.43e-40

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   3 PRLSLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQARELGIA 82
Cdd:COG4133     1 MMLEAENLSCRRGERLLFSGLSFTLAAGEALALTGPNGSGKTTLLRILAGLLPPSAGEVLWNGEPIRDAREDYRRRLAYL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  83 MvhQHFALFDTLSVTENVAL---GLSTGISAAEIEREIRLLGeKYGLEVDPASvvmELSMGERQRVEILRALMTKPKLLI 159
Cdd:COG4133    81 G--HADGLKPELTVRENLRFwaaLYGLRADREAIDEALEAVG-LAGLADLPVR---QLSAGQKRRVALARLLLSPAPLWL 154

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2549828669 160 LDEPTSVLTPQAVRKLFKTLHQLSSEGVSILFISHklDEIRELADRCVVLRAGK 213
Cdd:COG4133   155 LDEPFTALDAAGVALLAELIAAHLARGGAVLLTTH--QPLELAAARVLDLGDFK 206

MdlB

COG1132

ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];

4-217

7.66e-40

ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];

Pssm-ID: 440747 [Multi-domain] Cd Length: 579 Bit Score: 151.86 E-value: 7.66e-40

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   4 RLSLRNITKRYPG-ITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQARELgIA 82
Cdd:COG1132   339 EIEFENVSFSYPGdRPVLKDISLTIPPGETVALVGPSGSGKSTLVNLLLRFYDPTSGRILIDGVDIRDLTLESLRRQ-IG 417

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  83 MVHQHFALFDTlSVTENVALGlSTGISAAEIER---------EIRLLGEKYGLEVDPASVvmELSMGERQRVEILRALMT 153
Cdd:COG1132   418 VVPQDTFLFSG-TIRENIRYG-RPDATDEEVEEaakaaqaheFIEALPDGYDTVVGERGV--NLSGGQRQRIAIARALLK 493

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2549828669 154 KPKLLILDEPTSVLTPQAVRKLFKTLHQLsSEGVSILFISHKLDEIRElADRCVVLRAGKVVAS 217
Cdd:COG1132   494 DPPILILDEATSALDTETEALIQEALERL-MKGRTTIVIAHRLSTIRN-ADRILVLDDGRIVEQ 555

ModC

COG4148

ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and ...

9-263

2.15e-39

ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, ATPase component ModC is part of the Pathway/BioSystem: Molybdopterin biosynthesis

Pssm-ID: 443319 [Multi-domain] Cd Length: 358 Bit Score: 146.40 E-value: 2.15e-39

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   9 NITKRYPGITANdhVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPL-----GVETPAQARELGiaM 83
Cdd:COG4148     6 DFRLRRGGFTLD--VDFTLPGRGVTALFGPSGSGKTTLLRAIAGLERPDSGRIRLGGEVLqdsarGIFLPPHRRRIG--Y 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  84 VHQHFALFDTLSVTENVALGLS---TGISAAEIEREIRLLGEKYGLEVDPASvvmeLSMGERQRVEILRALMTKPKLLIL 160
Cdd:COG4148    82 VFQEARLFPHLSVRGNLLYGRKrapRAERRISFDEVVELLGIGHLLDRRPAT----LSGGERQRVAIGRALLSSPRLLLM 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 161 DEPTSVLTPQAVRKLFKTLHQLSSE-GVSILFISHKLDEIRELADRCVVLRAGKVVASvDPKAE--SEENLARLMIGNDP 237
Cdd:COG4148   158 DEPLAALDLARKAEILPYLERLRDElDIPILYVSHSLDEVARLADHVVLLEQGRVVAS-GPLAEvlSRPDLLPLAGGEEA 236

                         250       260
                  ....*....|....*....|....*.
gi 2549828669 238 PTVREGTAKAGEVVFEMRHVSAPGST 263
Cdd:COG4148   237 GSVLEATVAAHDPDYGLTRLALGGGR 262

ABC_ModC_molybdenum_transporter

cd03297

ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ...

4-217

3.10e-39

ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213264 [Multi-domain] Cd Length: 214 Bit Score: 141.66 E-value: 3.10e-39

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   4 RLSLRnITKRYPGITANdhVSLDIaPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPL-----GVETPAQARe 78
Cdd:cd03297     1 MLCVD-IEKRLPDFTLK--IDFDL-NEEVTGIFGASGAGKSTLLRCIAGLEKPDGGTIVLNGTVLfdsrkKINLPPQQR- 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  79 lGIAMVHQHFALFDTLSVTENVALGLStGISAAEIEREIRLLGEKYGLEVDPASVVMELSMGERQRVEILRALMTKPKLL 158
Cdd:cd03297    76 -KIGLVFQQYALFPHLNVRENLAFGLK-RKRNREDRISVDELLDLLGLDHLLNRYPAQLSGGEKQRVALARALAAQPELL 153

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 159 ILDEPTSVLTPQAVRKLFKTLHQLSSE-GVSILFISHKLDEIRELADRCVVLRAGKVVAS 217
Cdd:cd03297   154 LLDEPFSALDRALRLQLLPELKQIKKNlNIPVIFVTHDLSEAEYLADRIVVMEDGRLQYI 213

ABC_PstB_phosphate_transporter

cd03260

ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ...

5-221

1.31e-38

ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).

Pssm-ID: 213227 [Multi-domain] Cd Length: 227 Bit Score: 140.39 E-value: 1.31e-38

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   5 LSLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYG-----AARPDEGEISFDGHPL-GVETPAQARE 78
Cdd:cd03260     1 IELRDLNVYYGDKHALKDISLDIPKGEITALIGPSGCGKSTLLRLLNRlndliPGAPDEGEVLLDGKDIyDLDVDVLELR 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  79 LGIAMVHQHFALFDtLSVTENVALGLS-TGI-SAAEIEREIRLLGEKYGL--EVDPASVVMELSMGERQRVEILRALMTK 154
Cdd:cd03260    81 RRVGMVFQKPNPFP-GSIYDNVAYGLRlHGIkLKEELDERVEEALRKAALwdEVKDRLHALGLSGGQQQRLCLARALANE 159

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2549828669 155 PKLLILDEPTSVLTPQAVRKLFKTLHQLSSEgVSILFISHKLDEIRELADRCVVLRAGKVVASVDPK 221
Cdd:cd03260   160 PEVLLLDEPTSALDPISTAKIEELIAELKKE-YTIVIVTHNMQQAARVADRTAFLLNGRLVEFGPTE 225

ABC_Iron-Siderophores_B12_Hemin

cd03214

ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ...

6-217

1.54e-38

ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.

Pssm-ID: 213181 [Multi-domain] Cd Length: 180 Bit Score: 138.72 E-value: 1.54e-38

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   6 SLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQ-ARELGIamV 84
Cdd:cd03214     1 EVENLSVGYGGRTVLDDLSLSIEAGEIVGILGPNGAGKSTLLKTLAGLLKPSSGEILLDGKDLASLSPKElARKIAY--V 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  85 HQhfalfdtlsvtenvALGLsTGISAaeiereirlLGEKYglevdpasvVMELSMGERQRVEILRALMTKPKLLILDEPT 164
Cdd:cd03214    79 PQ--------------ALEL-LGLAH---------LADRP---------FNELSGGERQRVLLARALAQEPPILLLDEPT 125

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2549828669 165 SVLTPQAVRKLFKTLHQLS-SEGVSILFISHKLDEIRELADRCVVLRAGKVVAS 217
Cdd:cd03214   126 SHLDIAHQIELLELLRRLArERGKTVVMVLHDLNLAARYADRVILLKDGRIVAQ 179

ABC_OpuCA_Osmoprotection

cd03295

ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ...

5-215

5.93e-38

ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213262 [Multi-domain] Cd Length: 242 Bit Score: 138.97 E-value: 5.93e-38

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   5 LSLRNITKRYPGIT-ANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQARElGIAM 83
Cdd:cd03295     1 IEFENVTKRYGGGKkAVNNLNLEIAKGEFLVLIGPSGSGKTTTMKMINRLIEPTSGEIFIDGEDIREQDPVELRR-KIGY 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  84 VHQHFALFDTLSVTENVALGLS-TGISAAEIEREIRLLGEKYGLevDPASVV----MELSMGERQRVEILRALMTKPKLL 158
Cdd:cd03295    80 VIQQIGLFPHMTVEENIALVPKlLKWPKEKIRERADELLALVGL--DPAEFAdrypHELSGGQQQRVGVARALAADPPLL 157

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 159 ILDEPTSVLTP---QAVRKLFKTLHQLSseGVSILFISHKLDEIRELADRCVVLRAGKVV 215
Cdd:cd03295   158 LMDEPFGALDPitrDQLQEEFKRLQQEL--GKTIVFVTHDIDEAFRLADRIAIMKNGEIV 215

LPS_export_lptB

TIGR04406

LPS export ABC transporter ATP-binding protein; Members of this fmaily are LptB, the ...

4-221

6.44e-38

LPS export ABC transporter ATP-binding protein; Members of this fmaily are LptB, the ATP-binding cassette protein of an ABC transporter involved in lipopolysaccharide export. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other]

Pssm-ID: 275199 [Multi-domain] Cd Length: 239 Bit Score: 138.95 E-value: 6.44e-38

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   4 RLSLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLgVETPAQAR-ELGIA 82
Cdd:TIGR04406   1 TLVAENLIKSYKKRKVVNDVSLSVKSGEIVGLLGPNGAGKTTSFYMIVGLVRPDAGKILIDGQDI-THLPMHERaRLGIG 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  83 MVHQHFALFDTLSVTENV--ALGLSTGISAAEIEREIRLLGEKYGLEVDPASVVMELSMGERQRVEILRALMTKPKLLIL 160
Cdd:TIGR04406  80 YLPQEASIFRKLTVEENImaVLEIRKDLDRAEREERLEALLEEFQISHLRDNKAMSLSGGERRRVEIARALATNPKFILL 159

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2549828669 161 DEPTSVLTPQAVRKLFKTLHQLSSEGVSILFISHKLDEIRELADRCVVLRAGKVVASVDPK 221
Cdd:TIGR04406 160 DEPFAGVDPIAVGDIKKIIKHLKERGIGVLITDHNVRETLDICDRAYIISDGKVLAEGTPA 220

CydC

COG4987

ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease ...

3-221

9.19e-38

ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];

Pssm-ID: 444011 [Multi-domain] Cd Length: 569 Bit Score: 145.68 E-value: 9.19e-38

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   3 PRLSLRNITKRYPG--ITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQARELg 80
Cdd:COG4987   332 PSLELEDVSFRYPGagRPVLDGLSLTLPPGERVAIVGPSGSGKSTLLALLLRFLDPQSGSITLGGVDLRDLDEDDLRRR- 410

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  81 IAMVHQHFALFDTlSVTENVALG--------LSTGISAAEIEREIRLLGEKYGLEVDPASvvMELSMGERQRVEILRALM 152
Cdd:COG4987   411 IAVVPQRPHLFDT-TLRENLRLArpdatdeeLWAALERVGLGDWLAALPDGLDTWLGEGG--RRLSGGERRRLALARALL 487

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2549828669 153 TKPKLLILDEPTSVLTPQAVRKLFKTLHQLsSEGVSILFISHKLDEIrELADRCVVLRAGKVVASVDPK 221
Cdd:COG4987   488 RDAPILLLDEPTEGLDAATEQALLADLLEA-LAGRTVLLITHRLAGL-ERMDRILVLEDGRIVEQGTHE 554

ABC_Carb_Monos_II

cd03215

Second domain of the ATP-binding cassette component of monosaccharide transport system; This ...

3-214

1.10e-37

Pssm-ID: 213182 [Multi-domain] Cd Length: 182 Bit Score: 136.41 E-value: 1.10e-37

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   3 PRLSLRNITkrypGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQARELGIA 82
Cdd:cd03215     3 PVLEVRGLS----VKGAVRDVSFEVRAGEIVGIAGLVGNGQTELAEALFGLRPPASGEITLDGKPVTRRSPRDAIRAGIA 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  83 MV---HQHFALFDTLSVTENVALGLStgisaaeiereirllgekyglevdpasvvmeLSMGERQRVEILRALMTKPKLLI 159
Cdd:cd03215    79 YVpedRKREGLVLDLSVAENIALSSL-------------------------------LSGGNQQKVVLARWLARDPRVLI 127

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2549828669 160 LDEPTSVLTPQAVRKLFKTLHQLSSEGVSILFISHKLDEIRELADRCVVLRAGKV 214
Cdd:cd03215   128 LDEPTRGVDVGAKAEIYRLIRELADAGKAVLLISSELDELLGLCDRILVMYEGRI 182

ModF

COG1119

ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ...

2-231

1.16e-37

ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];

Pssm-ID: 440736 [Multi-domain] Cd Length: 250 Bit Score: 138.68 E-value: 1.16e-37

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   2 TPRLSLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEG-EISFDGHPLGVETPAQARELg 80
Cdd:COG1119     1 DPLLELRNVTVRRGGKTILDDISWTVKPGEHWAILGPNGAGKSTLLSLITGDLPPTYGnDVRLFGERRGGEDVWELRKR- 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  81 IAMVHQhfALFDTLSVTENV----------ALGLSTGISAAEIEREIRLLGEkYGLEVDPASVVMELSMGERQRVEILRA 150
Cdd:COG1119    80 IGLVSP--ALQLRFPRDETVldvvlsgffdSIGLYREPTDEQRERARELLEL-LGLAHLADRPFGTLSQGEQRRVLIARA 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 151 LMTKPKLLILDEPTSVLTPQAVRKLFKTLHQLSSEG-VSILFISHKLDEIRELADRCVVLRAGKVVASVdPKAE--SEEN 227
Cdd:COG1119   157 LVKDPELLILDEPTAGLDLGARELLLALLDKLAAEGaPTLVLVTHHVEEIPPGITHVLLLKDGRVVAAG-PKEEvlTSEN 235


                  ....
gi 2549828669 228 LARL 231
Cdd:COG1119   236 LSEA 239

TauB

COG4525

ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];

3-220

1.34e-37

ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];

Pssm-ID: 443596 [Multi-domain] Cd Length: 262 Bit Score: 138.84 E-value: 1.34e-37

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   3 PRLSLRNITKRYPGITAN----DHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPlgVETPAQARe 78
Cdd:COG4525     2 SMLTVRHVSVRYPGGGQPqpalQDVSLTIESGEFVVALGASGCGKTTLLNLIAGFLAPSSGEITLDGVP--VTGPGADR- 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  79 lgiAMVHQHFALFDTLSVTENVALGLS-TGISAAEIEREIRLLGEKYGLEVDPASVVMELSMGERQRVEILRALMTKPKL 157
Cdd:COG4525    79 ---GVVFQKDALLPWLNVLDNVAFGLRlRGVPKAERRARAEELLALVGLADFARRRIWQLSGGMRQRVGIARALAADPRF 155

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2549828669 158 LILDEPTSVL---TPQAVRKLFKTLHQLSseGVSILFISHKLDEIRELADRCVVL--RAGKVVASVDP 220
Cdd:COG4525   156 LLMDEPFGALdalTREQMQELLLDVWQRT--GKGVFLITHSVEEALFLATRLVVMspGPGRIVERLEL 221

modC_ABC

TIGR02142

molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding ...

9-216

1.53e-37

molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding cassette (ABC) protein of the three subunit molybdate ABC transporter. The three proteins of this complex are homologous to proteins of the sulfate ABC transporter. Molybdenum may be used in nitrogenases of nitrogen-fixing bacteria and in molybdopterin cofactors. In some cases, molybdate may be transported by a sulfate transporter rather than by a specific molybdate transporter. [Transport and binding proteins, Anions]

Pssm-ID: 131197 [Multi-domain] Cd Length: 354 Bit Score: 141.40 E-value: 1.53e-37

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   9 NITKRYPGITANdhVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPL-----GVETPAQARELGIam 83
Cdd:TIGR02142   4 RFSKRLGDFSLD--ADFTLPGQGVTAIFGRSGSGKTTLIRLIAGLTRPDEGEIVLNGRTLfdsrkGIFLPPEKRRIGY-- 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  84 VHQHFALFDTLSVTENVALGLS------TGISAAEIereIRLLGEKYGLEVDPASvvmeLSMGERQRVEILRALMTKPKL 157
Cdd:TIGR02142  80 VFQEARLFPHLSVRGNLRYGMKrarpseRRISFERV---IELLGIGHLLGRLPGR----LSGGEKQRVAIGRALLSSPRL 152

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 158 LILDEPTSVLTPQAVRKLFKTLHQLSSE-GVSILFISHKLDEIRELADRCVVLRAGKVVA 216
Cdd:TIGR02142 153 LLMDEPLAALDDPRKYEILPYLERLHAEfGIPILYVSHSLQEVLRLADRVVVLEDGRVAA 212

YejF

COG4172

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ...

1-290

5.25e-37

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];

Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 143.29 E-value: 5.25e-37

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   1 MTPRLSLRNITKRYPG----ITANDHVSLDIAPGEVLAILGENGAGKS-TLMKII----YGAARPDeGEISFDGHPLGVE 71
Cdd:COG4172     3 SMPLLSVEDLSVAFGQgggtVEAVKGVSFDIAAGETLALVGESGSGKSvTALSILrllpDPAAHPS-GSILFDGQDLLGL 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  72 TPAQAREL---GIAMVHQH--FALFDTLSVTENVA--LGLSTGISAAEIEREIRLLGEKYGLEvDPASVV----MELSMG 140
Cdd:COG4172    82 SERELRRIrgnRIAMIFQEpmTSLNPLHTIGKQIAevLRLHRGLSGAAARARALELLERVGIP-DPERRLdaypHQLSGG 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 141 ERQRVEILRALMTKPKLLILDEPTSVL--TPQA-VRKLFKTLHQlsSEGVSILFISHKLDEIRELADRCVVLRAGKVVAS 217
Cdd:COG4172   161 QRQRVMIAMALANEPDLLIADEPTTALdvTVQAqILDLLKDLQR--ELGMALLLITHDLGVVRRFADRVAVMRQGEIVEQ 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 218 vdpkAESEENLA-------RLMIGNDPPTVREGTAKAGEVVFEMRHVS----------APGSTRVCGIDNVSLAVRAGEI 280
Cdd:COG4172   239 ----GPTAELFAapqhpytRKLLAAEPRGDPRPVPPDAPPLLEARDLKvwfpikrglfRRTVGHVKAVDGVSLTLRRGET 314

                         330
                  ....*....|
gi 2549828669 281 VGIAGISGNG 290
Cdd:COG4172   315 LGLVGESGSG 324

glnQ

PRK09493

glutamine ABC transporter ATP-binding protein GlnQ;

7-241

5.70e-37

glutamine ABC transporter ATP-binding protein GlnQ;

Pssm-ID: 181906 [Multi-domain] Cd Length: 240 Bit Score: 136.38 E-value: 5.70e-37

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   7 LRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGhpLGVETPAQA-----RELGi 81
Cdd:PRK09493    4 FKNVSKHFGPTQVLHNIDLNIDQGEVVVIIGPSGSGKSTLLRCINKLEEITSGDLIVDG--LKVNDPKVDerlirQEAG- 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  82 aMVHQHFALFDTLSVTENVALG--LSTGISAAEIEREIRLLGEKYGLEVDPASVVMELSMGERQRVEILRALMTKPKLLI 159
Cdd:PRK09493   81 -MVFQQFYLFPHLTALENVMFGplRVRGASKEEAEKQARELLAKVGLAERAHHYPSELSGGQQQRVAIARALAVKPKLML 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 160 LDEPTSVLTPQAVRKLFKTLHQLSSEGVSILFISHKLDEIRELADRCVVLRAGKVVASVDPKAeseenlarlMIGNdPPT 239
Cdd:PRK09493  160 FDEPTSALDPELRHEVLKVMQDLAEEGMTMVIVTHEIGFAEKVASRLIFIDKGRIAEDGDPQV---------LIKN-PPS 229


                  ..
gi 2549828669 240 VR 241
Cdd:PRK09493  230 QR 231

ABC_FtsE

cd03292

Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ...

7-214

1.37e-36

Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages

Pssm-ID: 213259 [Multi-domain] Cd Length: 214 Bit Score: 134.46 E-value: 1.37e-36

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   7 LRNITKRYP-GITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPL----GVETPAQARELGi 81
Cdd:cd03292     3 FINVTKTYPnGTAALDGINISISAGEFVFLVGPSGAGKSTLLKLIYKEELPTSGTIRVNGQDVsdlrGRAIPYLRRKIG- 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  82 aMVHQHFALFDTLSVTENVALGLS-TGISAAEIEREIRLLGEKYGLEVDPASVVMELSMGERQRVEILRALMTKPKLLIL 160
Cdd:cd03292    82 -VVFQDFRLLPDRNVYENVAFALEvTGVPPREIRKRVPAALELVGLSHKHRALPAELSGGEQQRVAIARAIVNSPTILIA 160

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2549828669 161 DEPTSVLTPQAVRKLFKTLHQLSSEGVSILFISHKLDEIRELADRCVVLRAGKV 214
Cdd:cd03292   161 DEPTGNLDPDTTWEIMNLLKKINKAGTTVVVATHAKELVDTTRHRVIALERGKL 214

COG4559

ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];

5-230

2.41e-36

ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];

Pssm-ID: 443620 [Multi-domain] Cd Length: 258 Bit Score: 135.24 E-value: 2.41e-36

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   5 LSLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQ-ARELgiAM 83
Cdd:COG4559     2 LEAENLSVRLGGRTLLDDVSLTLRPGELTAIIGPNGAGKSTLLKLLTGELTPSSGEVRLNGRPLAAWSPWElARRR--AV 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  84 VHQHFAL-FDtLSVTENVALGLSTGISAAEIEREI-----------RLLGEKYglevdpasvvMELSMGERQRVEILRAL 151
Cdd:COG4559    80 LPQHSSLaFP-FTVEEVVALGRAPHGSSAAQDRQIvrealalvglaHLAGRSY----------QTLSGGEQQRVQLARVL 148

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 152 -------MTKPKLLILDEPTSVLTPQAVRKLFKTLHQLSSEGVSILFISHKLDEIRELADRCVVLRAGKVVASVDPkAE- 223
Cdd:COG4559   149 aqlwepvDGGPRWLFLDEPTSALDLAHQHAVLRLARQLARRGGGVVAVLHDLNLAAQYADRILLLHQGRLVAQGTP-EEv 227


                  ....*...
gi 2549828669 224 -SEENLAR 230
Cdd:COG4559   228 lTDELLER 235

LptB

COG1137

ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope ...

3-221

2.70e-36

ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope biogenesis];

Pssm-ID: 440752 [Multi-domain] Cd Length: 240 Bit Score: 134.39 E-value: 2.70e-36

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   3 PRLSLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLgveTP----AQARe 78
Cdd:COG1137     2 MTLEAENLVKSYGKRTVVKDVSLEVNQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGRIFLDGEDI---THlpmhKRAR- 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  79 LGIAMVHQHFALFDTLSVTENVALGLST-GISAAEIEREIRLLGEKYGLE--VD-PAsvvMELSMGERQRVEILRALMTK 154
Cdd:COG1137    78 LGIGYLPQEASIFRKLTVEDNILAVLELrKLSKKEREERLEELLEEFGIThlRKsKA---YSLSGGERRRVEIARALATN 154

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2549828669 155 PKLLILDEPTSVLTPQAVRKLFKTLHQLSSEGVSILFISHKLDEIRELADRCVVLRAGKVVASVDPK 221
Cdd:COG1137   155 PKFILLDEPFAGVDPIAVADIQKIIRHLKERGIGVLITDHNVRETLGICDRAYIISEGKVLAEGTPE 221

PRK13536

nodulation factor ABC transporter ATP-binding protein NodI;

5-237

4.14e-36

nodulation factor ABC transporter ATP-binding protein NodI;

Pssm-ID: 237419 [Multi-domain] Cd Length: 340 Bit Score: 136.88 E-value: 4.14e-36

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   5 LSLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFdghpLGVETPAQAR--ELGIA 82
Cdd:PRK13536   42 IDLAGVSKSYGDKAVVNGLSFTVASGECFGLLGPNGAGKSTIARMILGMTSPDAGKITV----LGVPVPARARlaRARIG 117

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  83 MVHQhfalFDTL----SVTEN-VALGLSTGISAAEIEREIRLLGEKYGLEVDPASVVMELSMGERQRVEILRALMTKPKL 157
Cdd:PRK13536  118 VVPQ----FDNLdlefTVRENlLVFGRYFGMSTREIEAVIPSLLEFARLESKADARVSDLSGGMKRRLTLARALINDPQL 193

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 158 LILDEPTSVLTPQAVRKLFKTLHQLSSEGVSILFISHKLDEIRELADRCVVLRAGKVVASVDPKAESEENLARLMI---G 234
Cdd:PRK13536  194 LILDEPTTGLDPHARHLIWERLRSLLARGKTILLTTHFMEEAERLCDRLCVLEAGRKIAEGRPHALIDEHIGCQVIeiyG 273


                  ...
gi 2549828669 235 NDP 237
Cdd:PRK13536  274 GDP 276

cbiO

PRK13635

energy-coupling factor ABC transporter ATP-binding protein;

1-238

6.80e-36

energy-coupling factor ABC transporter ATP-binding protein;

Pssm-ID: 184195 [Multi-domain] Cd Length: 279 Bit Score: 134.76 E-value: 6.80e-36

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   1 MTPRLSLRNITKRYPGIT--ANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQARE 78
Cdd:PRK13635    2 KEEIIRVEHISFRYPDAAtyALKDVSFSVYEGEWVAIVGHNGSGKSTLAKLLNGLLLPEAGTITVGGMVLSEETVWDVRR 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  79 LgIAMVHQH-FALFDTLSVTENVALGL-STGISAAE-IER---EIRLLGEKYGLEVDPASvvmeLSMGERQRVEILRALM 152
Cdd:PRK13635   82 Q-VGMVFQNpDNQFVGATVQDDVAFGLeNIGVPREEmVERvdqALRQVGMEDFLNREPHR----LSGGQKQRVAIAGVLA 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 153 TKPKLLILDEPTSVLTPQAVRKLFKTLHQLSSE-GVSILFISHKLDEIRElADRCVVLRAGKVVASVDPKAESEENLARL 231
Cdd:PRK13635  157 LQPDIIILDEATSMLDPRGRREVLETVRQLKEQkGITVLSITHDLDEAAQ-ADRVIVMNKGEILEEGTPEEIFKSGHMLQ 235


                  ....*..
gi 2549828669 232 MIGNDPP 238
Cdd:PRK13635  236 EIGLDVP 242

YejF

COG4172

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ...

2-215

7.03e-36

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];

Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 139.82 E-value: 7.03e-36

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   2 TPRLSLRNITKRYPG-----------ITANDHVSLDIAPGEVLAILGENGAGKSTL----MKIIygaarPDEGEISFDGH 66
Cdd:COG4172   273 PPLLEARDLKVWFPIkrglfrrtvghVKAVDGVSLTLRRGETLGLVGESGSGKSTLglalLRLI-----PSEGEIRFDGQ 347

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  67 PLGVETPAQAREL--GIAMVHQH-FALFDT-LSVTENVALGLST---GISAAEIEREIRLLGEKYGLevDPASvvM---- 135
Cdd:COG4172   348 DLDGLSRRALRPLrrRMQVVFQDpFGSLSPrMTVGQIIAEGLRVhgpGLSAAERRARVAEALEEVGL--DPAA--Rhryp 423

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 136 -ELSMGERQRVEILRALMTKPKLLILDEPTSVL--TPQA-VRKLFKTLHQlsSEGVSILFISHKLDEIRELADRCVVLRA 211
Cdd:COG4172   424 hEFSGGQRQRIAIARALILEPKLLVLDEPTSALdvSVQAqILDLLRDLQR--EHGLAYLFISHDLAVVRALAHRVMVMKD 501


                  ....
gi 2549828669 212 GKVV 215
Cdd:COG4172   502 GKVV 505

met_CoM_red_A2

TIGR03269

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ...

5-471

9.32e-36

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]

Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 139.55 E-value: 9.32e-36

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   5 LSLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYG--AARPDEGEI----------------SFDGH 66
Cdd:TIGR03269   1 IEVKNLTKKFDGKEVLKNISFTIEEGEVLGILGRSGAGKSVLMHVLRGmdQYEPTSGRIiyhvalcekcgyverpSKVGE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  67 PLGV------------------ETPAQARELGIaMVHQHFALFDTLSVTENVALGL-STGISAAE-IEREIRLLgEKYGL 126
Cdd:TIGR03269  81 PCPVcggtlepeevdfwnlsdkLRRRIRKRIAI-MLQRTFALYGDDTVLDNVLEALeEIGYEGKEaVGRAVDLI-EMVQL 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 127 EVDPASVVMELSMGERQRVEILRALMTKPKLLILDEPTSVLTPQAVRKLFKTLHQL-SSEGVSILFISHKLDEIRELADR 205
Cdd:TIGR03269 159 SHRITHIARDLSGGEKQRVVLARQLAKEPFLFLADEPTGTLDPQTAKLVHNALEEAvKASGISMVLTSHWPEVIEDLSDK 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 206 CVVLRAGKVVASVDPkaesEENLARLMIGNDPPTvREGTAKAGEVVFEMRHVsapgSTRVCGI--------DNVSLAVRA 277
Cdd:TIGR03269 239 AIWLENGEIKEEGTP----DEVVAVFMEGVSEVE-KECEVEVGEPIIKVRNV----SKRYISVdrgvvkavDNVSLEVKE 309

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 278 GEIVGIAGISGNGQ---ARFMAA----ASGEYLCE-ADRVLLFNSPVGELDTHARRISGLRYVPEQRLGHAAVPElSLTA 349
Cdd:TIGR03269 310 GEIFGIVGTSGAGKttlSKIIAGvlepTSGEVNVRvGDEWVDMTKPGPDGRGRAKRYIGILHQEYDLYPHRTVLD-NLTE 388

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 350 NTYLT-GDSLVRSGFILRDRARSFANLVIERFHVKTPNaekaagSLSGGNLQKFIMGREILNRPRVLLVHQPTWGVDVGA 428
Cdd:TIGR03269 389 AIGLElPDELARMKAVITLKMVGFDEEKAEEILDKYPD------ELSEGERHRVALAQVLIKEPRIVILDEPTGTMDPIT 462

                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....
gi 2549828669 429 AAVIRNSLIRLRDD-GAAIIVVSEEIDELFEISDRIAVMYRGAL 471
Cdd:TIGR03269 463 KVDVTHSILKAREEmEQTFIIVSHDMDFVLDVCDRAALMRDGKI 506

potA

PRK09452

spermidine/putrescine ABC transporter ATP-binding protein PotA;

2-214

1.35e-35

spermidine/putrescine ABC transporter ATP-binding protein PotA;

Pssm-ID: 236523 [Multi-domain] Cd Length: 375 Bit Score: 136.23 E-value: 1.35e-35

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   2 TPRLSLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLgVETPAQARElgI 81
Cdd:PRK09452   12 SPLVELRGISKSFDGKEVISNLDLTINNGEFLTLLGPSGCGKTTVLRLIAGFETPDSGRIMLDGQDI-THVPAENRH--V 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  82 AMVHQHFALFDTLSVTENVALGLS-TGISAAEIE-------REIRLlgEKYGlEVDPAsvvmELSMGERQRVEILRALMT 153
Cdd:PRK09452   89 NTVFQSYALFPHMTVFENVAFGLRmQKTPAAEITprvmealRMVQL--EEFA-QRKPH----QLSGGQQQRVAIARAVVN 161

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2549828669 154 KPKLLILDEPTSVLTPQAVRKLFKTLHQLSSE-GVSILFISHKLDEIRELADRCVVLRAGKV 214
Cdd:PRK09452  162 KPKVLLLDESLSALDYKLRKQMQNELKALQRKlGITFVFVTHDQEEALTMSDRIVVMRDGRI 223

ABCC_bacteriocin_exporters

cd03245

ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ...

4-216

2.87e-35

ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.

Pssm-ID: 213212 [Multi-domain] Cd Length: 220 Bit Score: 131.17 E-value: 2.87e-35

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   4 RLSLRNITKRYPG--ITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQARElGI 81
Cdd:cd03245     2 RIEFRNVSFSYPNqeIPALDNVSLTIRAGEKVAIIGRVGSGKSTLLKLLAGLYKPTSGSVLLDGTDIRQLDPADLRR-NI 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  82 AMVHQHFALFDTlSVTENVALGlSTGISAAEIEREIRLLG-------EKYGLEVDPASVVMELSMGERQRVEILRALMTK 154
Cdd:cd03245    81 GYVPQDVTLFYG-TLRDNITLG-APLADDERILRAAELAGvtdfvnkHPNGLDLQIGERGRGLSGGQRQAVALARALLND 158

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2549828669 155 PKLLILDEPTSVLTPQAVRKLFKTLHQLSSeGVSILFISHKLdEIRELADRCVVLRAGKVVA 216
Cdd:cd03245   159 PPILLLDEPTSAMDMNSEERLKERLRQLLG-DKTLIIITHRP-SLLDLVDRIIVMDSGRIVA 218

PRK13537

nodulation factor ABC transporter ATP-binding protein NodI;

1-270

2.99e-35

nodulation factor ABC transporter ATP-binding protein NodI;

Pssm-ID: 237420 [Multi-domain] Cd Length: 306 Bit Score: 133.78 E-value: 2.99e-35

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   1 MTPRLSLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLgvetPAQARE-- 78
Cdd:PRK13537    4 SVAPIDFRNVEKRYGDKLVVDGLSFHVQRGECFGLLGPNGAGKTTTLRMLLGLTHPDAGSISLCGEPV----PSRARHar 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  79 LGIAMVHQHFALFDTLSVTENV-ALGLSTGISAAEIEREIRLLGEKYGLEVDPASVVMELSMGERQRVEILRALMTKPKL 157
Cdd:PRK13537   80 QRVGVVPQFDNLDPDFTVRENLlVFGRYFGLSAAAARALVPPLLEFAKLENKADAKVGELSGGMKRRLTLARALVNDPDV 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 158 LILDEPTSVLTPQAVRKLFKTLHQLSSEGVSILFISHKLDEIRELADRCVVLRAGKVVASVDPKA--ESEENLARLMI-G 234
Cdd:PRK13537  160 LVLDEPTTGLDPQARHLMWERLRSLLARGKTILLTTHFMEEAERLCDRLCVIEEGRKIAEGAPHAliESEIGCDVIEIyG 239

                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 2549828669 235 NDPPTVREGTAKAGEvvfemrHVSAPGSTRVCGIDN 270
Cdd:PRK13537  240 PDPVALRDELAPLAE------RTEISGETLFCYVRD 269

hmuV

PRK13548

hemin importer ATP-binding subunit; Provisional

3-230

3.47e-35

hemin importer ATP-binding subunit; Provisional

Pssm-ID: 237422 [Multi-domain] Cd Length: 258 Bit Score: 132.20 E-value: 3.47e-35

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   3 PRLSLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQ-ARELgi 81
Cdd:PRK13548    1 AMLEARNLSVRLGGRTLLDDVSLTLRPGEVVAILGPNGAGKSTLLRALSGELSPDSGEVRLNGRPLADWSPAElARRR-- 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  82 AMVHQHFAL-FDtLSVTENVALGLST-GISAAEIEREIRLLGEKYGLEVDPASVVMELSMGERQRVEILRALM------T 153
Cdd:PRK13548   79 AVLPQHSSLsFP-FTVEEVVAMGRAPhGLSRAEDDALVAAALAQVDLAHLAGRDYPQLSGGEQQRVQLARVLAqlwepdG 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 154 KPKLLILDEPTSVLTPQAVRKLFKTLHQLSSE-GVSILFISHKLDEIRELADRCVVLRAGKVVASvDPKAE--SEENLAR 230
Cdd:PRK13548  158 PPRWLLLDEPTSALDLAHQHHVLRLARQLAHErGLAVIVVLHDLNLAARYADRIVLLHQGRLVAD-GTPAEvlTPETLRR 236

ABC_cobalt_CbiO_domain2

cd03226

Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of ...

6-215

7.35e-35

Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.

Pssm-ID: 213193 [Multi-domain] Cd Length: 205 Bit Score: 129.68 E-value: 7.35e-35

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   6 SLRNITKRYP-GITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLgvetPAQARELGIAMV 84
Cdd:cd03226     1 RIENISFSYKkGTEILDDLSLDLYAGEIIALTGKNGAGKTTLAKILAGLIKESSGSILLNGKPI----KAKERRKSIGYV 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  85 HQH--FALFdTLSVTENVALGL-STGISAAEIEREIRLLGEKYGLEVDPASvvmeLSMGERQRVEILRALMTKPKLLILD 161
Cdd:cd03226    77 MQDvdYQLF-TDSVREELLLGLkELDAGNEQAETVLKDLDLYALKERHPLS----LSGGQKQRLAIAAALLSGKDLLIFD 151

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2549828669 162 EPTSVLTPQAVRKLFKTLHQLSSEGVSILFISHKLDEIRELADRCVVLRAGKVV 215
Cdd:cd03226   152 EPTSGLDYKNMERVGELIRELAAQGKAVIVITHDYEFLAKVCDRVLLLANGAIV 205

L_ocin_972_ABC

TIGR03608

putative bacteriocin export ABC transporter, lactococcin 972 group; A gene pair with a fairly ...

7-209

7.46e-35

putative bacteriocin export ABC transporter, lactococcin 972 group; A gene pair with a fairly wide distribution consists of a polypeptide related to the lactococcin 972 (see TIGR01653) and multiple-membrane-spanning putative immunity protein (see TIGR01654). This model represents a small clade within the ABC transporters that regularly are found adjacent to these bacteriocin system gene pairs and are likely serve as export proteins. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]

Pssm-ID: 188353 [Multi-domain] Cd Length: 206 Bit Score: 129.66 E-value: 7.46e-35

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   7 LRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQAREL---GIAM 83
Cdd:TIGR03608   1 LKNISKKFGDKVILDDLNLTIEKGKMYAIIGESGSGKSTLLNIIGLLEKFDSGQVYLNGQETPPLNSKKASKFrreKLGY 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  84 VHQHFALFDTLSVTENVALGLS-TGISAAEIEREIRLLGEKYGLEVDPASVVMELSMGERQRVEILRALMTKPKLLILDE 162
Cdd:TIGR03608  81 LFQNFALIENETVEENLDLGLKyKKLSKKEKREKKKEALEKVGLNLKLKQKIYELSGGEQQRVALARAILKPPPLILADE 160

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 2549828669 163 PTSVLTPQAVRKLFKTLHQLSSEGVSILFISHKLdEIRELADRCVVL 209
Cdd:TIGR03608 161 PTGSLDPKNRDEVLDLLLELNDEGKTIIIVTHDP-EVAKQADRVIEL 206

ABC_DrrA

cd03265

Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ...

9-216

2.68e-34

Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213232 [Multi-domain] Cd Length: 220 Bit Score: 128.64 E-value: 2.68e-34

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   9 NITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLgVETPAQARElGIAMVHQHF 88
Cdd:cd03265     5 NLVKKYGDFEAVRGVSFRVRRGEIFGLLGPNGAGKTTTIKMLTTLLKPTSGRATVAGHDV-VREPREVRR-RIGIVFQDL 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  89 ALFDTLSVTENVAL-GLSTGISAAEIEREIRLLGEKYGLEVDPASVVMELSMGERQRVEILRALMTKPKLLILDEPTSVL 167
Cdd:cd03265    83 SVDDELTGWENLYIhARLYGVPGAERRERIDELLDFVGLLEAADRLVKTYSGGMRRRLEIARSLVHRPEVLFLDEPTIGL 162

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 2549828669 168 TPQAVRKLFKTLHQL-SSEGVSILFISHKLDEIRELADRCVVLRAGKVVA 216
Cdd:cd03265   163 DPQTRAHVWEYIEKLkEEFGMTILLTTHYMEEAEQLCDRVAIIDHGRIIA 212

MsbA_lipidA

TIGR02203

lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide ...

4-215

3.29e-34

lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide chain transporter in the ATP-binding cassette (ABC) transporter family, MsbA, which exports lipid A. It may also act in multidrug resistance. Lipid A, a part of lipopolysaccharide, is found in the outer leaflet of the outer membrane of most Gram-negative bacteria. Members of this family are restricted to the Proteobacteria (although lipid A is more broadly distributed) and often are clustered with lipid A biosynthesis genes. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other]

Pssm-ID: 131258 [Multi-domain] Cd Length: 571 Bit Score: 135.61 E-value: 3.29e-34

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   4 RLSLRNITKRYPG--ITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQARElGI 81
Cdd:TIGR02203 330 DVEFRNVTFRYPGrdRPALDSISLVIEPGETVALVGRSGSGKSTLVNLIPRFYEPDSGQILLDGHDLADYTLASLRR-QV 408

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  82 AMVHQHFALFDTlSVTENVALGLSTGISAAEIEREIRLLGEK-------YGLEVDPASVVMELSMGERQRVEILRALMTK 154
Cdd:TIGR02203 409 ALVSQDVVLFND-TIANNIAYGRTEQADRAEIERALAAAYAQdfvdklpLGLDTPIGENGVLLSGGQRQRLAIARALLKD 487

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2549828669 155 PKLLILDEPTSVLTPQAVRKLFKTLHQLsSEGVSILFISHKLDEIrELADRCVVLRAGKVV 215
Cdd:TIGR02203 488 APILILDEATSALDNESERLVQAALERL-MQGRTTLVIAHRLSTI-EKADRIVVMDDGRIV 546

AppF

COG4608

ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; ...

1-215

3.83e-34

ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism];

Pssm-ID: 443658 [Multi-domain] Cd Length: 329 Bit Score: 131.01 E-value: 3.83e-34

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   1 MTPRLSLRNITKRYPG-----------ITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLG 69
Cdd:COG4608     4 AEPLLEVRDLKKHFPVrgglfgrtvgvVKAVDGVSFDIRRGETLGLVGESGCGKSTLGRLLLRLEEPTSGEILFDGQDIT 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  70 VETPAQAREL--GIAMVHQH-FALFDT-LSVTENVALGL--STGISAAEIEREIRLLGEKYGLEVD-----PAsvvmELS 138
Cdd:COG4608    84 GLSGRELRPLrrRMQMVFQDpYASLNPrMTVGDIIAEPLriHGLASKAERRERVAELLELVGLRPEhadryPH----EFS 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 139 MGERQRVEILRALMTKPKLLILDEPTSVL--TPQA-VRKLFKTLHQlssE-GVSILFISHKLDEIRELADRCVVLRAGKV 214
Cdd:COG4608   160 GGQRQRIGIARALALNPKLIVCDEPVSALdvSIQAqVLNLLEDLQD---ElGLTYLFISHDLSVVRHISDRVAVMYLGKI 236


                  .
gi 2549828669 215 V 215
Cdd:COG4608   237 V 237

ABC_drug_resistance_like

cd03264

ABC-type multidrug transport system, ATPase component; The biological function of this family ...

5-217

5.37e-34

ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213231 [Multi-domain] Cd Length: 211 Bit Score: 127.31 E-value: 5.37e-34

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   5 LSLRNITKRYPGITANDHVSLDIAPGeVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPlGVETPAQARELgIAMV 84
Cdd:cd03264     1 LQLENLTKRYGKKRALDGVSLTLGPG-MYGLLGPNGAGKTTLMRILATLTPPSSGTIRIDGQD-VLKQPQKLRRR-IGYL 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  85 HQHFALFDTLSVTENVA-LGLSTGISAAEIEREIRLLGEKYGLEVDPASVVMELSMGERQRVEILRALMTKPKLLILDEP 163
Cdd:cd03264    78 PQEFGVYPNFTVREFLDyIAWLKGIPSKEVKARVDEVLELVNLGDRAKKKIGSLSGGMRRRVGIAQALVGDPSILIVDEP 157

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2549828669 164 TSVLTPqAVRKLFKTLHQLSSEGVSILFISHKLDEIRELADRCVVLRAGKVVAS 217
Cdd:cd03264   158 TAGLDP-EERIRFRNLLSELGEDRIVILSTHIVEDVESLCNQVAVLNKGKLVFE 210

livF

PRK11614

high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;

1-215

6.49e-34

high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;

Pssm-ID: 183231 [Multi-domain] Cd Length: 237 Bit Score: 128.07 E-value: 6.49e-34

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   1 MTPRLSLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQARELG 80
Cdd:PRK11614    2 EKVMLSFDKVSAHYGKIQALHEVSLHINQGEIVTLIGANGAGKTTLLGTLCGDPRATSGRIVFDGKDITDWQTAKIMREA 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  81 IAMVHQHFALFDTLSVTENVALGlstGISAAE------IEREIRLLGEKYGLEVDPASVvmeLSMGERQRVEILRALMTK 154
Cdd:PRK11614   82 VAIVPEGRRVFSRMTVEENLAMG---GFFAERdqfqerIKWVYELFPRLHERRIQRAGT---MSGGEQQMLAIGRALMSQ 155

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2549828669 155 PKLLILDEPTSVLTPQAVRKLFKTLHQLSSEGVSILFISHKLDEIRELADRCVVLRAGKVV 215
Cdd:PRK11614  156 PRLLLLDEPSLGLAPIIIQQIFDTIEQLREQGMTIFLVEQNANQALKLADRGYVLENGHVV 216

cbiO

PRK13632

cobalt transporter ATP-binding subunit; Provisional

2-221

1.35e-33

cobalt transporter ATP-binding subunit; Provisional

Pssm-ID: 237452 [Multi-domain] Cd Length: 271 Bit Score: 128.18 E-value: 1.35e-33

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   2 TPRLSLRNITKRYPGITAN--DHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQARE- 78
Cdd:PRK13632    5 SVMIKVENVSFSYPNSENNalKNVSFEINEGEYVAILGHNGSGKSTISKILTGLLKPQSGEIKIDGITISKENLKEIRKk 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  79 LGIamVHQH-FALFDTLSVTENVALGLSTG-ISAAEIEREIRLLGEKYG----LEVDPASvvmeLSMGERQRVEILRALM 152
Cdd:PRK13632   85 IGI--IFQNpDNQFIGATVEDDIAFGLENKkVPPKKMKDIIDDLAKKVGmedyLDKEPQN----LSGGQKQRVAIASVLA 158

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 153 TKPKLLILDEPTSVLTPQAVRKLFKTLHQLSSEGV-SILFISHKLDEIReLADRCVVLRAGKVVASVDPK 221
Cdd:PRK13632  159 LNPEIIIFDESTSMLDPKGKREIKKIMVDLRKTRKkTLISITHDMDEAI-LADKVIVFSEGKLIAQGKPK 227

potG

PRK11607

putrescine ABC transporter ATP-binding subunit PotG;

1-221

2.95e-33

putrescine ABC transporter ATP-binding subunit PotG;

Pssm-ID: 183226 [Multi-domain] Cd Length: 377 Bit Score: 129.96 E-value: 2.95e-33

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   1 MTPRLSLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQARelg 80
Cdd:PRK11607   16 LTPLLEIRNLTKSFDGQHAVDDVSLTIYKGEIFALLGASGCGKSTLLRMLAGFEQPTAGQIMLDGVDLSHVPPYQRP--- 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  81 IAMVHQHFALFDTLSVTENVALGLSTG-ISAAEIEREIRLLGEKYGLEVDPASVVMELSMGERQRVEILRALMTKPKLLI 159
Cdd:PRK11607   93 INMMFQSYALFPHMTVEQNIAFGLKQDkLPKAEIASRVNEMLGLVHMQEFAKRKPHQLSGGQRQRVALARSLAKRPKLLL 172

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2549828669 160 LDEPTSVLTPQAVRKL-FKTLHQLSSEGVSILFISHKLDEIRELADRCVVLRAGKVVASVDPK 221
Cdd:PRK11607  173 LDEPMGALDKKLRDRMqLEVVDILERVGVTCVMVTHDQEEAMTMAGRIAIMNRGKFVQIGEPE 235

PRK10851

sulfate/thiosulfate ABC transporter ATP-binding protein CysA;

9-214

5.24e-33

sulfate/thiosulfate ABC transporter ATP-binding protein CysA;

Pssm-ID: 182778 [Multi-domain] Cd Length: 353 Bit Score: 128.66 E-value: 5.24e-33

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   9 NITKRYpGITA--NDhVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLgveTPAQARELGIAMVHQ 86
Cdd:PRK10851    7 NIKKSF-GRTQvlND-ISLDIPSGQMVALLGPSGSGKTTLLRIIAGLEHQTSGHIRFHGTDV---SRLHARDRKVGFVFQ 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  87 HFALFDTLSVTENVALGLST-----GISAAEIEREIRLLGEKYGLEVDPASVVMELSMGERQRVEILRALMTKPKLLILD 161
Cdd:PRK10851   82 HYALFRHMTVFDNIAFGLTVlprreRPNAAAIKAKVTQLLEMVQLAHLADRYPAQLSGGQKQRVALARALAVEPQILLLD 161

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2549828669 162 EPTSVLTPQAVRKLFKTLHQLSSE-GVSILFISHKLDEIRELADRCVVLRAGKV 214
Cdd:PRK10851  162 EPFGALDAQVRKELRRWLRQLHEElKFTSVFVTHDQEEAMEVADRVVVMSQGNI 215

CydD

TIGR02857

thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ...

3-209

6.72e-33

thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD

Pssm-ID: 274323 [Multi-domain] Cd Length: 529 Bit Score: 131.25 E-value: 6.72e-33

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   3 PRLSLRNITKRYPGIT-ANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQARElGI 81
Cdd:TIGR02857 320 SSLEFSGVSVAYPGRRpALRPVSFTVPPGERVALVGPSGAGKSTLLNLLLGFVDPTEGSIAVNGVPLADADADSWRD-QI 398

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  82 AMVHQHFALFDTlSVTENVALGLStGISAAEIEREIRL---------LGEKYGLEVDPASVvmELSMGERQRVEILRALM 152
Cdd:TIGR02857 399 AWVPQHPFLFAG-TIAENIRLARP-DASDAEIREALERagldefvaaLPQGLDTPIGEGGA--GLSGGQAQRLALARAFL 474

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2549828669 153 TKPKLLILDEPTSVLTPQAVRKLFKTLHQLsSEGVSILFISHKLdEIRELADRCVVL 209
Cdd:TIGR02857 475 RDAPLLLLDEPTAHLDAETEAEVLEALRAL-AQGRTVLLVTHRL-ALAALADRIVVL 529

ABC_ThiQ_thiamine_transporter

cd03298

ATP-binding cassette domain of the thiamine transport system; Part of the ...

5-216

8.18e-33

ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213265 [Multi-domain] Cd Length: 211 Bit Score: 124.14 E-value: 8.18e-33

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   5 LSLRNITKRYPgiTANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAqarELGIAMV 84
Cdd:cd03298     1 VRLDKIRFSYG--EQPMHFDLTFAQGEITAIVGPSGSGKSTLLNLIAGFETPQSGRVLINGVDVTAAPPA---DRPVSML 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  85 HQHFALFDTLSVTENVALGLSTGISAAEIERE-IRLLGEKYGLEVDPASVVMELSMGERQRVEILRALMTKPKLLILDEP 163
Cdd:cd03298    76 FQENNLFAHLTVEQNVGLGLSPGLKLTAEDRQaIEVALARVGLAGLEKRLPGELSGGERQRVALARVLVRDKPVLLLDEP 155

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2549828669 164 TSVLTP---QAVRKLFKTLHQlsSEGVSILFISHKLDEIRELADRCVVLRAGKVVA 216
Cdd:cd03298   156 FAALDPalrAEMLDLVLDLHA--ETKMTVLMVTHQPEDAKRLAQRVVFLDNGRIAA 209

ABCC_Hemolysin

cd03252

ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ...

5-215

8.73e-33

ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.

Pssm-ID: 213219 [Multi-domain] Cd Length: 237 Bit Score: 124.91 E-value: 8.73e-33

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   5 LSLRNITKRYPGITAN--DHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQAR-ELGI 81
Cdd:cd03252     1 ITFEHVRFRYKPDGPVilDNISLRIKPGEVVGIVGRSGSGKSTLTKLIQRFYVPENGRVLVDGHDLALADPAWLRrQVGV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  82 AMvhQHFALFDTlSVTENVALGlSTGISAAEIEREIRLLG---------EKYGLEVDPASVvmELSMGERQRVEILRALM 152
Cdd:cd03252    81 VL--QENVLFNR-SIRDNIALA-DPGMSMERVIEAAKLAGahdfiselpEGYDTIVGEQGA--GLSGGQRQRIAIARALI 154

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2549828669 153 TKPKLLILDEPTSVLTPQAVRKLFKTLHQLSSeGVSILFISHKLDEIRElADRCVVLRAGKVV 215
Cdd:cd03252   155 HNPRILIFDEATSALDYESEHAIMRNMHDICA-GRTVIIIAHRLSTVKN-ADRIIVMEKGRIV 215

livG

PRK11300

leucine/isoleucine/valine transporter ATP-binding subunit; Provisional

1-241

9.99e-33

leucine/isoleucine/valine transporter ATP-binding subunit; Provisional

Pssm-ID: 183080 [Multi-domain] Cd Length: 255 Bit Score: 125.49 E-value: 9.99e-33

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   1 MTPRLSLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQARELG 80
Cdd:PRK11300    2 SQPLLSVSGLMMRFGGLLAVNNVNLEVREQEIVSLIGPNGAGKTTVFNCLTGFYKPTGGTILLRGQHIEGLPGHQIARMG 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  81 IAMVHQHFALFDTLSVTEN--VA--LGLSTGISA----------AE---IEREIRLLgEKYGLEVDPASVVMELSMGERQ 143
Cdd:PRK11300   82 VVRTFQHVRLFREMTVIENllVAqhQQLKTGLFSgllktpafrrAEseaLDRAATWL-ERVGLLEHANRQAGNLAYGQQR 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 144 RVEILRALMTKPKLLILDEPTSVLTPQAVRKLFKTLHQLSSE-GVSILFISHKLDEIRELADRCVVLRAGKVVASVDPKA 222
Cdd:PRK11300  161 RLEIARCMVTQPEILMLDEPAAGLNPKETKELDELIAELRNEhNVTVLLIEHDMKLVMGISDRIYVVNQGTPLANGTPEE 240

                         250
                  ....*....|....*....
gi 2549828669 223 eseenlarlmIGNDPPTVR 241
Cdd:PRK11300  241 ----------IRNNPDVIK 249

YbbA

COG4181

Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase ...

2-223

2.62e-32

Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component [Secondary metabolites biosynthesis, transport and catabolism];

Pssm-ID: 443338 [Multi-domain] Cd Length: 233 Bit Score: 123.31 E-value: 2.62e-32

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   2 TPRLSLRNITKRYPG----ITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGV---ETPA 74
Cdd:COG4181     6 APIIELRGLTKTVGTgageLTILKGISLEVEAGESVAIVGASGSGKSTLLGLLAGLDRPTSGTVRLAGQDLFAldeDARA 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  75 QARELGIAMVHQHFALFDTLSVTENVALGLS-TGISAAEiEREIRLLgEKYGLE--VD--PAsvvmELSMGERQRVEILR 149
Cdd:COG4181    86 RLRARHVGFVFQSFQLLPTLTALENVMLPLElAGRRDAR-ARARALL-ERVGLGhrLDhyPA----QLSGGEQQRVALAR 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 150 ALMTKPKLLILDEPTSVL---TPQAVRKLFKTLHQLSseGVSILFISHklDEirELADRC---VVLRAGKVVASVDPKAE 223
Cdd:COG4181   160 AFATEPAILFADEPTGNLdaaTGEQIIDLLFELNRER--GTTLVLVTH--DP--ALAARCdrvLRLRAGRLVEDTAATAA 233

ABC_MTABC3_MDL1_MDL2

cd03249

ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ...

7-215

3.56e-32

ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.

Pssm-ID: 213216 [Multi-domain] Cd Length: 238 Bit Score: 123.42 E-value: 3.56e-32

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   7 LRNITKRYP---GITANDHVSLDIAPGEVLAILGENGAGKSTLMKII---YGaarPDEGEISFDGHPLGVETPAQARELg 80
Cdd:cd03249     3 FKNVSFRYPsrpDVPILKGLSLTIPPGKTVALVGSSGCGKSTVVSLLerfYD---PTSGEILLDGVDIRDLNLRWLRSQ- 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  81 IAMVHQHFALFDTlSVTENVALGLSTGIS--------AAEIEREIRLLGEKYGLEVDPASVvmELSMGERQRVEILRALM 152
Cdd:cd03249    79 IGLVSQEPVLFDG-TIAENIRYGKPDATDeeveeaakKANIHDFIMSLPDGYDTLVGERGS--QLSGGQKQRIAIARALL 155

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2549828669 153 TKPKLLILDEPTSVLTPQAVRKLFKTLHQLsSEGVSILFISHKLDEIRElADRCVVLRAGKVV 215
Cdd:cd03249   156 RNPKILLLDEATSALDAESEKLVQEALDRA-MKGRTTIVIAHRLSTIRN-ADLIAVLQNGQVV 216

modC

PRK11144

molybdenum ABC transporter ATP-binding protein ModC;

23-217

4.46e-32

molybdenum ABC transporter ATP-binding protein ModC;

Pssm-ID: 182993 [Multi-domain] Cd Length: 352 Bit Score: 126.14 E-value: 4.46e-32

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  23 VSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPL-----GVETPAQARELGiaMVHQHFALFDTLSVT 97
Cdd:PRK11144   17 VNLTLPAQGITAIFGRSGAGKTSLINAISGLTRPQKGRIVLNGRVLfdaekGICLPPEKRRIG--YVFQDARLFPHYKVR 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  98 ENVALGLStGISAAEIEREIRLLGEKYGLEVDPASvvmeLSMGERQRVEILRALMTKPKLLILDEPTSVLTPQAVRKLFK 177
Cdd:PRK11144   95 GNLRYGMA-KSMVAQFDKIVALLGIEPLLDRYPGS----LSGGEKQRVAIGRALLTAPELLLMDEPLASLDLPRKRELLP 169

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 2549828669 178 TLHQLSSE-GVSILFISHKLDEIRELADRCVVLRAGKVVAS 217
Cdd:PRK11144  170 YLERLAREiNIPILYVSHSLDEILRLADRVVVLEQGKVKAF 210

phnK

PRK11701

phosphonate C-P lyase system protein PhnK; Provisional

1-217

6.94e-32

phosphonate C-P lyase system protein PhnK; Provisional

Pssm-ID: 183280 [Multi-domain] Cd Length: 258 Bit Score: 123.11 E-value: 6.94e-32

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   1 MTPRLSLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISF---DGHPLGVETPAQAR 77
Cdd:PRK11701    3 DQPLLSVRGLTKLYGPRKGCRDVSFDLYPGEVLGIVGESGSGKTTLLNALSARLAPDAGEVHYrmrDGQLRDLYALSEAE 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  78 -------ELGIamVHQHfalfdtlsvtenVALGLSTGISA-AEIEREIRLLGEK-YG------------LEVDPASV--- 133
Cdd:PRK11701   83 rrrllrtEWGF--VHQH------------PRDGLRMQVSAgGNIGERLMAVGARhYGdiratagdwlerVEIDAARIddl 148

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 134 VMELSMGERQRVEILRALMTKPKLLILDEPTSVL--TPQAvrKLFKTLHQLSSE-GVSILFISHKLDEIRELADRCVVLR 210
Cdd:PRK11701  149 PTTFSGGMQQRLQIARNLVTHPRLVFMDEPTGGLdvSVQA--RLLDLLRGLVRElGLAVVIVTHDLAVARLLAHRLLVMK 226


                  ....*..
gi 2549828669 211 AGKVVAS 217
Cdd:PRK11701  227 QGRVVES 233

COG4586

ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...

6-215

1.46e-31

ABC-type uncharacterized transport system, ATPase component [General function prediction only];

Pssm-ID: 443643 [Multi-domain] Cd Length: 323 Bit Score: 124.04 E-value: 1.46e-31

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   6 SLRNITKR-YPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHplgveTPAQ-----AREL 79
Cdd:COG4586    23 ALKGLFRReYREVEAVDDISFTIEPGEIVGFIGPNGAGKSTTIKMLTGILVPTSGEVRVLGY-----VPFKrrkefARRI 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  80 GIAM-----VHQHFALFDTLSVtenvaLGLSTGISAAEIEREIRLLGEKygLEVDP--ASVVMELSMGERQRVEILRALM 152
Cdd:COG4586    98 GVVFgqrsqLWWDLPAIDSFRL-----LKAIYRIPDAEYKKRLDELVEL--LDLGEllDTPVRQLSLGQRMRCELAAALL 170

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2549828669 153 TKPKLLILDEPT---SVLTPQAVRKLFKTLHQlsSEGVSILFISHKLDEIRELADRCVVLRAGKVV 215
Cdd:COG4586   171 HRPKILFLDEPTiglDVVSKEAIREFLKEYNR--ERGTTILLTSHDMDDIEALCDRVIVIDHGRII 234

ABCC_MsbA

cd03251

ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ...

5-215

2.24e-31

ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213218 [Multi-domain] Cd Length: 234 Bit Score: 120.80 E-value: 2.24e-31

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   5 LSLRNITKRYPGITAN--DHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQARELgIA 82
Cdd:cd03251     1 VEFKNVTFRYPGDGPPvlRDISLDIPAGETVALVGPSGSGKSTLVNLIPRFYDVDSGRILIDGHDVRDYTLASLRRQ-IG 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  83 MVHQHFALFDTlSVTENVALGLStGISAAEIEREIRL---------LGEKYGLEVDPASVvmELSMGERQRVEILRALMT 153
Cdd:cd03251    80 LVSQDVFLFND-TVAENIAYGRP-GATREEVEEAARAanahefimeLPEGYDTVIGERGV--KLSGGQRQRIAIARALLK 155

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2549828669 154 KPKLLILDEPTSVLTPQAVRKLFKTLHQLsSEGVSILFISHKLDEIRElADRCVVLRAGKVV 215
Cdd:cd03251   156 DPPILILDEATSALDTESERLVQAALERL-MKNRTTFVIAHRLSTIEN-ADRIVVLEDGKIV 215

cbiO

PRK13639

cobalt transporter ATP-binding subunit; Provisional

5-221

3.63e-31

cobalt transporter ATP-binding subunit; Provisional

Pssm-ID: 184199 [Multi-domain] Cd Length: 275 Bit Score: 121.72 E-value: 3.63e-31

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   5 LSLRNITKRYP-GITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPA--QARE-LG 80
Cdd:PRK13639    2 LETRDLKYSYPdGTEALKGINFKAEKGEMVALLGPNGAGKSTLFLHFNGILKPTSGEVLIKGEPIKYDKKSllEVRKtVG 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  81 IAMVHQHFALFDTlSVTENVALG-LSTGISAAEIEREIRLLGEKYGLEVDPASVVMELSMGERQRVEILRALMTKPKLLI 159
Cdd:PRK13639   82 IVFQNPDDQLFAP-TVEEDVAFGpLNLGLSKEEVEKRVKEALKAVGMEGFENKPPHHLSGGQKKRVAIAGILAMKPEIIV 160

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2549828669 160 LDEPTSVLTPQAVRKLFKTLHQLSSEGVSILFISHKLDEIRELADRCVVLRAGKVVASVDPK 221
Cdd:PRK13639  161 LDEPTSGLDPMGASQIMKLLYDLNKEGITIIISTHDVDLVPVYADKVYVMSDGKIIKEGTPK 222

LolD_lipo_ex

TIGR02211

lipoprotein releasing system, ATP-binding protein; This model represents LolD, a member of the ...

5-216

6.30e-31

lipoprotein releasing system, ATP-binding protein; This model represents LolD, a member of the ABC transporter family (pfam00005). LolD is involved in localization of lipoproteins in some bacteria. It works with a transmembrane protein LolC, which in some species is a paralogous pair LolC and LolE. Depending on whether the residue immediately following the new, modified N-terminal Cys residue, the nascent lipoprotein may be carried further by LolA and LolB to the outer membrane, or remain at the inner membrane. The top scoring proteins excluded by this model include homologs from the archaeal genus Methanosarcina. [Protein fate, Protein and peptide secretion and trafficking]

Pssm-ID: 131266 [Multi-domain] Cd Length: 221 Bit Score: 119.38 E-value: 6.30e-31

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   5 LSLRNITKRYP----GITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDG---HPLGVETPAQAR 77
Cdd:TIGR02211   2 LKCENLGKRYQegklDTRVLKGVSLSIGKGEIVAIVGSSGSGKSTLLHLLGGLDNPTSGEVLFNGqslSKLSSNERAKLR 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  78 ELGIAMVHQHFALFDTLSVTENVALGLSTG-ISAAEIEREIRLLGEKYGLEVDPASVVMELSMGERQRVEILRALMTKPK 156
Cdd:TIGR02211  82 NKKLGFIYQFHHLLPDFTALENVAMPLLIGkKSVKEAKERAYEMLEKVGLEHRINHRPSELSGGERQRVAIARALVNQPS 161

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2549828669 157 LLILDEPTSVLTPQAVRKLFKTLHQLSSE-GVSILFISHKLDEIRELaDRCVVLRAGKVVA 216
Cdd:TIGR02211 162 LVLADEPTGNLDNNNAKIIFDLMLELNRElNTSFLVVTHDLELAKKL-DRVLEMKDGQLFN 221

ABCC_Protease_Secretion

cd03246

ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ...

5-214

6.40e-31

ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.

Pssm-ID: 213213 [Multi-domain] Cd Length: 173 Bit Score: 117.70 E-value: 6.40e-31

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   5 LSLRNITKRYPGITAN--DHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQARELgIA 82
Cdd:cd03246     1 LEVENVSFRYPGAEPPvlRNVSFSIEPGESLAIIGPSGSGKSTLARLILGLLRPTSGRVRLDGADISQWDPNELGDH-VG 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  83 MVHQHFALFDTlSVTENValglstgisaaeiereirllgekyglevdpasvvmeLSMGERQRVEILRALMTKPKLLILDE 162
Cdd:cd03246    80 YLPQDDELFSG-SIAENI------------------------------------LSGGQRQRLGLARALYGNPRILVLDE 122

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2549828669 163 PTSVLTPQAVRKLFKTLHQLSSEGVSILFISHKLdEIRELADRCVVLRAGKV 214
Cdd:cd03246   123 PNSHLDVEGERALNQAIAALKAAGATRIVIAHRP-ETLASADRILVLEDGRV 173

fbpC

PRK11432

ferric ABC transporter ATP-binding protein;

5-222

1.52e-30

ferric ABC transporter ATP-binding protein;

Pssm-ID: 183133 [Multi-domain] Cd Length: 351 Bit Score: 121.75 E-value: 1.52e-30

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   5 LSLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLgVETPAQARElgIAMV 84
Cdd:PRK11432    7 VVLKNITKRFGSNTVIDNLNLTIKQGTMVTLLGPSGCGKTTVLRLVAGLEKPTEGQIFIDGEDV-THRSIQQRD--ICMV 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  85 HQHFALFDTLSVTENVALGLST-GISAAEIEREIrllgeKYGLE-VDPASV----VMELSMGERQRVEILRALMTKPKLL 158
Cdd:PRK11432   84 FQSYALFPHMSLGENVGYGLKMlGVPKEERKQRV-----KEALElVDLAGFedryVDQISGGQQQRVALARALILKPKVL 158

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2549828669 159 ILDEPTSVLTPQAVRKLFKTLHQLSSE-GVSILFISHKLDEIRELADRCVVLRAGKVVASVDPKA 222
Cdd:PRK11432  159 LFDEPLSNLDANLRRSMREKIRELQQQfNITSLYVTHDQSEAFAVSDTVIVMNKGKIMQIGSPQE 223

potA

TIGR01187

spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine ...

35-226

2.30e-30

spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine/putrescine ABC transporter, ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. Polyamines like spermidine and putrescine play vital role in cell proliferation, differentiation, and ion homeostasis. The concentration of polyamines within the cell are regulated by biosynthesis, degradation and transport (uptake and efflux included). [Transport and binding proteins, Amino acids, peptides and amines]

Pssm-ID: 162242 [Multi-domain] Cd Length: 325 Bit Score: 120.68 E-value: 2.30e-30

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  35 ILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLgVETPAQARelGIAMVHQHFALFDTLSVTENVALGLST-GISAAEI 113
Cdd:TIGR01187   1 LLGPSGCGKTTLLRLLAGFEQPDSGSIMLDGEDV-TNVPPHLR--HINMVFQSYALFPHMTVEENVAFGLKMrKVPRAEI 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 114 EREIRLLGEKYGLEVDPASVVMELSMGERQRVEILRALMTKPKLLILDEPTSVLT----PQAVRKLFKTLHQLsseGVSI 189
Cdd:TIGR01187  78 KPRVLEALRLVQLEEFADRKPHQLSGGQQQRVALARALVFKPKILLLDEPLSALDkklrDQMQLELKTIQEQL---GITF 154

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 2549828669 190 LFISHKLDEIRELADRCVVLRAGKVVASVDPKAESEE 226
Cdd:TIGR01187 155 VFVTHDQEEAMTMSDRIAIMRKGKIAQIGTPEEIYEE 191

ArtP

COG4161

ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];

5-215

2.58e-30

ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];

Pssm-ID: 443326 [Multi-domain] Cd Length: 242 Bit Score: 118.19 E-value: 2.58e-30

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   5 LSLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVET---PAQAREL-- 79
Cdd:COG4161     3 IQLKNINCFYGSHQALFDINLECPSGETLVLLGPSGAGKSSLLRVLNLLETPDSGQLNIAGHQFDFSQkpsEKAIRLLrq 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  80 GIAMVHQHFALFDTLSVTENV------ALGLStgiSAAEIEREIRLLGEkygLEVDPASVV--MELSMGERQRVEILRAL 151
Cdd:COG4161    83 KVGMVFQQYNLWPHLTVMENLieapckVLGLS---KEQAREKAMKLLAR---LRLTDKADRfpLHLSGGQQQRVAIARAL 156

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2549828669 152 MTKPKLLILDEPTSVLTPQAVRKLFKTLHQLSSEGVSILFISHKLDEIRELADRCVVLRAGKVV 215
Cdd:COG4161   157 MMEPQVLLFDEPTAALDPEITAQVVEIIRELSQTGITQVIVTHEVEFARKVASQVVYMEKGRII 220

ugpC

PRK11650

sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;

5-214

3.29e-30

sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;

Pssm-ID: 236947 [Multi-domain] Cd Length: 356 Bit Score: 120.72 E-value: 3.29e-30

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   5 LSLRNITKRYPG-ITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAqarELGIAM 83
Cdd:PRK11650    4 LKLQAVRKSYDGkTQVIKGIDLDVADGEFIVLVGPSGCGKSTLLRMVAGLERITSGEIWIGGRVVNELEPA---DRDIAM 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  84 VHQHFALFDTLSVTENVALGLST-GISAAEIEREI----RLLG-EKYgLEVDPAsvvmELSMGERQRVEILRALMTKPKL 157
Cdd:PRK11650   81 VFQNYALYPHMSVRENMAYGLKIrGMPKAEIEERVaeaaRILElEPL-LDRKPR----ELSGGQRQRVAMGRAIVREPAV 155

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 158 LILDEPTSVLTPQ---AVRKLFKTLHQlsSEGVSILFISHKLDEIRELADRCVVLRAGKV 214
Cdd:PRK11650  156 FLFDEPLSNLDAKlrvQMRLEIQRLHR--RLKTTSLYVTHDQVEAMTLADRVVVMNGGVA 213

PhnK

COG1101

ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...

5-228

4.32e-30

ABC-type uncharacterized transport system, ATPase component [General function prediction only];

Pssm-ID: 440718 [Multi-domain] Cd Length: 264 Bit Score: 118.26 E-value: 4.32e-30

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   5 LSLRNITKR-YPGiTAN-----DHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLgVETPAQARE 78
Cdd:COG1101     2 LELKNLSKTfNPG-TVNekralDGLNLTIEEGDFVTVIGSNGAGKSTLLNAIAGSLPPDSGSILIDGKDV-TKLPEYKRA 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  79 LGIAMVHQhfalfD-------TLSVTENVAL--------GLSTGISAAEIER---EIRLLGekYGLEVDPASVVMELSMG 140
Cdd:COG1101    80 KYIGRVFQ-----DpmmgtapSMTIEENLALayrrgkrrGLRRGLTKKRRELfreLLATLG--LGLENRLDTKVGLLSGG 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 141 ERQRVEILRALMTKPKLLILDEPTSVLTPQAVRKLFKTLHQLSSE-GVSILFISHKLDEIRELADRCVVLRAGKVVasVD 219
Cdd:COG1101   153 QRQALSLLMATLTKPKLLLLDEHTAALDPKTAALVLELTEKIVEEnNLTTLMVTHNMEQALDYGNRLIMMHEGRII--LD 230


                  ....*....
gi 2549828669 220 PKAESEENL 228
Cdd:COG1101   231 VSGEEKKKL 239

PRK11264

putative amino-acid ABC transporter ATP-binding protein YecC; Provisional

7-222

4.54e-30

putative amino-acid ABC transporter ATP-binding protein YecC; Provisional

Pssm-ID: 183063 [Multi-domain] Cd Length: 250 Bit Score: 117.93 E-value: 4.54e-30

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   7 LRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEG-----EISFDG-HPLGvETPAQAREL- 79
Cdd:PRK11264    6 VKNLVKKFHGQTVLHGIDLEVKPGEVVAIIGPSGSGKTTLLRCINLLEQPEAGtirvgDITIDTaRSLS-QQKGLIRQLr 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  80 -GIAMVHQHFALFDTLSVTENVALG--LSTGISAAEIEREIRLLGEKYGLEVDPASVVMELSMGERQRVEILRALMTKPK 156
Cdd:PRK11264   85 qHVGFVFQNFNLFPHRTVLENIIEGpvIVKGEPKEEATARARELLAKVGLAGKETSYPRRLSGGQQQRVAIARALAMRPE 164

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2549828669 157 LLILDEPTSVLTPQAVRKLFKTLHQLSSEGVSILFISHKLDEIRELADRCVVLRAGKVVASVDPKA 222
Cdd:PRK11264  165 VILFDEPTSALDPELVGEVLNTIRQLAQEKRTMVIVTHEMSFARDVADRAIFMDQGRIVEQGPAKA 230

ABC_NatA_like

cd03267

ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ...

6-216

9.70e-30

ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.

Pssm-ID: 213234 [Multi-domain] Cd Length: 236 Bit Score: 116.66 E-value: 9.70e-30

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   6 SLRNITKR-YPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQARELGIAMv 84
Cdd:cd03267    22 SLKSLFKRkYREVEALKGISFTIEKGEIVGFIGPNGAGKTTTLKILSGLLQPTSGEVRVAGLVPWKRRKKFLRRIGVVF- 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  85 HQHFALFDTLSVTENVALGLST-GISAAEIEREIRLLGEKYGLEVDPASVVMELSMGERQRVEILRALMTKPKLLILDEP 163
Cdd:cd03267   101 GQKTQLWWDLPVIDSFYLLAAIyDLPPARFKKRLDELSELLDLEELLDTPVRQLSLGQRMRAEIAAALLHEPEILFLDEP 180

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2549828669 164 TSVLTPQAVRKLFKTLHQLSSE-GVSILFISHKLDEIRELADRCVVLRAGKVVA 216
Cdd:cd03267   181 TIGLDVVAQENIRNFLKEYNRErGTTVLLTSHYMKDIEALARRVLVIDKGRLLY 234

YnjD

COG4136

ABC-type uncharacterized transport system YnjBCD, ATPase component [General function ...

5-211

1.33e-29

ABC-type uncharacterized transport system YnjBCD, ATPase component [General function prediction only];

Pssm-ID: 443311 [Multi-domain] Cd Length: 211 Bit Score: 115.27 E-value: 1.33e-29

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   5 LSLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPD---EGEISFDGHPLGvETPAQARELGI 81
Cdd:COG4136     2 LSLENLTITLGGRPLLAPLSLTVAPGEILTLMGPSGSGKSTLLAAIAGTLSPAfsaSGEVLLNGRRLT-ALPAEQRRIGI 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  82 AMvhQHFALFDTLSVTENVALGLSTGISAAEIEREIRLLGEKYGL----EVDPAsvvmELSMGERQRVEILRALMTKPKL 157
Cdd:COG4136    81 LF--QDDLLFPHLSVGENLAFALPPTIGRAQRRARVEQALEEAGLagfaDRDPA----TLSGGQRARVALLRALLAEPRA 154

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2549828669 158 LILDEPTSVLTP---QAVRKL-FKTLHQLsseGVSILFISHKLDEIrELADRCVVLRA 211
Cdd:COG4136   155 LLLDEPFSKLDAalrAQFREFvFEQIRQR---GIPALLVTHDEEDA-PAAGRVLDLGN 208

TagH

COG1134

ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ...

1-221

1.40e-29

ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];

Pssm-ID: 440749 [Multi-domain] Cd Length: 245 Bit Score: 116.33 E-value: 1.40e-29

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   1 MTPRLSLRNITKRYP----------------------GITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDE 58
Cdd:COG1134     1 MSSMIEVENVSKSYRlyhepsrslkelllrrrrtrreEFWALKDVSFEVERGESVGIIGRNGAGKSTLLKLIAGILEPTS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  59 GEISFDGH---PLgvetpaqarELGIAMVHQhfalfdtLSVTENVAL-GLSTGISAAEIER---EIRL---LGEKygleV 128
Cdd:COG1134    81 GRVEVNGRvsaLL---------ELGAGFHPE-------LTGRENIYLnGRLLGLSRKEIDEkfdEIVEfaeLGDF----I 140

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 129 D-PasvVMELSMGERQRveiLR---ALMTKPKLLILDEPTSVLTPQAVRKLFKTLHQLSSEGVSILFISHKLDEIRELAD 204
Cdd:COG1134   141 DqP---VKTYSSGMRAR---LAfavATAVDPDILLVDEVLAVGDAAFQKKCLARIRELRESGRTVIFVSHSMGAVRRLCD 214

                         250
                  ....*....|....*..
gi 2549828669 205 RCVVLRAGKVVASVDPK 221
Cdd:COG1134   215 RAIWLEKGRLVMDGDPE 231

tauB

PRK11248

taurine ABC transporter ATP-binding subunit;

5-212

1.63e-29

taurine ABC transporter ATP-binding subunit;

Pssm-ID: 183056 [Multi-domain] Cd Length: 255 Bit Score: 116.34 E-value: 1.63e-29

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   5 LSLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPlgVETPAQARelgiAMV 84
Cdd:PRK11248    2 LQISHLYADYGGKPALEDINLTLESGELLVVLGPSGCGKTTLLNLIAGFVPYQHGSITLDGKP--VEGPGAER----GVV 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  85 HQHFALFDTLSVTENVALGLS-TGISAAEIEREIRLLGEKYGLEVDPASVVMELSMGERQRVEILRALMTKPKLLILDEP 163
Cdd:PRK11248   76 FQNEGLLPWRNVQDNVAFGLQlAGVEKMQRLEIAHQMLKKVGLEGAEKRYIWQLSGGQRQRVGIARALAANPQLLLLDEP 155

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2549828669 164 TSVL---TPQAVRKLFKTLHQLSseGVSILFISHKLDEIRELADRCVVLRAG 212
Cdd:PRK11248  156 FGALdafTREQMQTLLLKLWQET--GKQVLLITHDIEEAVFMATELVLLSPG 205

artP

PRK11124

arginine transporter ATP-binding subunit; Provisional

5-215

2.39e-29

arginine transporter ATP-binding subunit; Provisional

Pssm-ID: 182980 [Multi-domain] Cd Length: 242 Bit Score: 115.50 E-value: 2.39e-29

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   5 LSLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVET---PAQAREL-- 79
Cdd:PRK11124    3 IQLNGINCFYGAHQALFDITLDCPQGETLVLLGPSGAGKSSLLRVLNLLEMPRSGTLNIAGNHFDFSKtpsDKAIRELrr 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  80 GIAMVHQHFALFDTLSVTENV------ALGLStgiSAAEIEREIRLLgEKYGLEVDPASVVMELSMGERQRVEILRALMT 153
Cdd:PRK11124   83 NVGMVFQQYNLWPHLTVQQNLieapcrVLGLS---KDQALARAEKLL-ERLRLKPYADRFPLHLSGGQQQRVAIARALMM 158

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2549828669 154 KPKLLILDEPTSVLTPQAVRKLFKTLHQLSSEGVSILFISHKLDEIRELADRCVVLRAGKVV 215
Cdd:PRK11124  159 EPQVLLFDEPTAALDPEITAQIVSIIRELAETGITQVIVTHEVEVARKTASRVVYMENGHIV 220

PRK10619

histidine ABC transporter ATP-binding protein HisP;

4-222

4.32e-29

histidine ABC transporter ATP-binding protein HisP;

Pssm-ID: 182592 [Multi-domain] Cd Length: 257 Bit Score: 115.45 E-value: 4.32e-29

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   4 RLSLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGH----------PLGVETP 73
Cdd:PRK10619    5 KLNVIDLHKRYGEHEVLKGVSLQANAGDVISIIGSSGSGKSTFLRCINFLEKPSEGSIVVNGQtinlvrdkdgQLKVADK 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  74 AQARELG--IAMVHQHFALFDTLSVTENV------ALGLStgiSAAEIEREIRLLgEKYGL-EVDPASVVMELSMGERQR 144
Cdd:PRK10619   85 NQLRLLRtrLTMVFQHFNLWSHMTVLENVmeapiqVLGLS---KQEARERAVKYL-AKVGIdERAQGKYPVHLSGGQQQR 160

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2549828669 145 VEILRALMTKPKLLILDEPTSVLTPQAVRKLFKTLHQLSSEGVSILFISHKLDEIRELADRCVVLRAGKVVASVDPKA 222
Cdd:PRK10619  161 VSIARALAMEPEVLLFDEPTSALDPELVGEVLRIMQQLAEEGKTMVVVTHEMGFARHVSSHVIFLHQGKIEEEGAPEQ 238

ABCG_EPDR

cd03213

Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ...

4-215

5.69e-29

Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.

Pssm-ID: 213180 [Multi-domain] Cd Length: 194 Bit Score: 113.03 E-value: 5.69e-29

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   4 RLSLRNITKRYPGITANDH------VSLDIAPGEVLAILGENGAGKSTLMKIIYGAARP--DEGEISFDGHPLGVETPAQ 75
Cdd:cd03213     3 TLSFRNLTVTVKSSPSKSGkqllknVSGKAKPGELTAIMGPSGAGKSTLLNALAGRRTGlgVSGEVLINGRPLDKRSFRK 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  76 ArelgIAMVHQHFALFDTLSVTENVALglstgisAAEIEReirllgekyglevdpasvvmeLSMGERQRVEILRALMTKP 155
Cdd:cd03213    83 I----IGYVPQDDILHPTLTVRETLMF-------AAKLRG---------------------LSGGERKRVSIALELVSNP 130

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2549828669 156 KLLILDEPTSVLTPQAVRKLFKTLHQLSSEGVSILFISHKL-DEIRELADRCVVLRAGKVV 215
Cdd:cd03213   131 SLLFLDEPTSGLDSSSALQVMSLLRRLADTGRTIICSIHQPsSEIFELFDKLLLLSQGRVI 191

met_CoM_red_A2

TIGR03269

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ...

3-221

5.76e-29

Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 119.91 E-value: 5.76e-29

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   3 PRLSLRNITKRYPG-----ITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISF-------DGHPLGV 70
Cdd:TIGR03269 278 PIIKVRNVSKRYISvdrgvVKAVDNVSLEVKEGEIFGIVGTSGAGKTTLSKIIAGVLEPTSGEVNVrvgdewvDMTKPGP 357

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  71 ETPAQARELgIAMVHQHFALFDTLSVTENV--ALGLSTGISAAEIEREIRL----LGEKYGLEVDPaSVVMELSMGERQR 144
Cdd:TIGR03269 358 DGRGRAKRY-IGILHQEYDLYPHRTVLDNLteAIGLELPDELARMKAVITLkmvgFDEEKAEEILD-KYPDELSEGERHR 435

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2549828669 145 VEILRALMTKPKLLILDEPTSVLTPQAVRKLFKTLHQLSSE-GVSILFISHKLDEIRELADRCVVLRAGKVVASVDPK 221
Cdd:TIGR03269 436 VALAQVLIKEPRIVILDEPTGTMDPITKVDVTHSILKAREEmEQTFIIVSHDMDFVLDVCDRAALMRDGKIVKIGDPE 513

nickel_nikE

TIGR02769

nickel import ATP-binding protein NikE; This family represents the NikE subunit of a ...

5-219

7.90e-29

nickel import ATP-binding protein NikE; This family represents the NikE subunit of a multisubunit nickel import ABC transporter complex. Nickel, once imported, may be used in urease and in certain classes of hydrogenase and superoxide dismutase. [Transport and binding proteins, Cations and iron carrying compounds]

Pssm-ID: 131816 [Multi-domain] Cd Length: 265 Bit Score: 114.90 E-value: 7.90e-29

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   5 LSLRNITKRYPG---------ITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQ 75
Cdd:TIGR02769   3 LEVRDVTHTYRTgglfgakqrAPVLTNVSLSIEEGETVGLLGRSGCGKSTLARLLLGLEKPAQGTVSFRGQDLYQLDRKQ 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  76 AREL--GIAMVHQ--HFALFDTLSVTENVALGLS--TGISAAEIEREIRLLGEKYGLEVDPAS-VVMELSMGERQRVEIL 148
Cdd:TIGR02769  83 RRAFrrDVQLVFQdsPSAVNPRMTVRQIIGEPLRhlTSLDESEQKARIAELLDMVGLRSEDADkLPRQLSGGQLQRINIA 162

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2549828669 149 RALMTKPKLLILDEPTS----VLTPQAVRkLFKTLHQLSseGVSILFISHKLDEIRELADRCVVLRAGKVVASVD 219
Cdd:TIGR02769 163 RALAVKPKLIVLDEAVSnldmVLQAVILE-LLRKLQQAF--GTAYLFITHDLRLVQSFCQRVAVMDKGQIVEECD 234

ABCC_cytochrome_bd

cd03247

ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ...

5-217

9.78e-29

ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.

Pssm-ID: 213214 [Multi-domain] Cd Length: 178 Bit Score: 112.02 E-value: 9.78e-29

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   5 LSLRNITKRYPG--ITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPlgVETPAQARELGIA 82
Cdd:cd03247     1 LSINNVSFSYPEqeQQVLKNLSLELKQGEKIALLGRSGSGKSTLLQLLTGDLKPQQGEITLDGVP--VSDLEKALSSLIS 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  83 MVHQHFALFDTlSVTENvalglstgisaaeiereirlLGEKyglevdpasvvmeLSMGERQRVEILRALMTKPKLLILDE 162
Cdd:cd03247    79 VLNQRPYLFDT-TLRNN--------------------LGRR-------------FSGGERQRLALARILLQDAPIVLLDE 124

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2549828669 163 PTSVLTPQAVRKLFKTLHQLsSEGVSILFISHKLDEIrELADRCVVLRAGKVVAS 217
Cdd:cd03247   125 PTVGLDPITERQLLSLIFEV-LKDKTLIWITHHLTGI-EHMDKILFLENGKIIMQ 177

Uup

COG0488

ATPase components of ABC transporters with duplicated ATPase domains [General function ...

7-290

1.19e-28

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];

Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 119.01 E-value: 1.19e-28

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   7 LRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFdghplgvetPAQARelgIAMVHQ 86
Cdd:COG0488     1 LENLSKSFGGRPLLDDVSLSINPGDRIGLVGRNGAGKSTLLKILAGELEPDSGEVSI---------PKGLR---IGYLPQ 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  87 HFALFDTLSVTENVALGLStgiSAAEIEREIRLLGEKY----------------------------------GL---EVD 129
Cdd:COG0488    69 EPPLDDDLTVLDTVLDGDA---ELRALEAELEELEAKLaepdedlerlaelqeefealggweaearaeeilsGLgfpEED 145

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 130 PASVVMELSMGERQRVEILRALMTKPKLLILDEPTSVLTPQAVRKLFKTLHQLSSegvSILFISHKLDEIRELADRCVVL 209
Cdd:COG0488   146 LDRPVSELSGGWRRRVALARALLSEPDLLLLDEPTNHLDLESIEWLEEFLKNYPG---TVLVVSHDRYFLDRVATRILEL 222

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 210 RAGKVV-------ASVDPKAESEEN-----------LARL--------------------------MIGNDPPtVREGTA 245
Cdd:COG0488   223 DRGKLTlypgnysAYLEQRAERLEQeaaayakqqkkIAKEeefirrfrakarkakqaqsrikalekLEREEPP-RRDKTV 301

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2549828669 246 K--------AGEVVFEMRHVS-APGSTRVcgIDNVSLAVRAGEIVGIAGISGNG 290
Cdd:COG0488   302 EirfppperLGKKVLELEGLSkSYGDKTL--LDDLSLRIDRGDRIGLIGPNGAG 353

ntrCD

TIGR01184

nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits ...

21-212

1.37e-28

nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits of nitrate transport in bacteria and archaea. This protein belongs to the ATP-binding cassette (ABC) superfamily. It is thought that the two subunits encoded by ntrC and ntrD form the binding surface for interaction with ATP. This model is restricted in identifying ATP binding subunit associated with the nitrate transport. Nitrate assimilation is aided by other proteins derived from the operon which among others include products of ntrA - a regulatory protein; ntrB - a hydropbobic transmembrane permease and narB - a reductase. [Transport and binding proteins, Anions, Transport and binding proteins, Other]

Pssm-ID: 130252 [Multi-domain] Cd Length: 230 Bit Score: 113.33 E-value: 1.37e-28

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  21 DHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPlgVETPAQARelgiAMVHQHFALFDTLSVTENV 100
Cdd:TIGR01184   2 KGVNLTIQQGEFISLIGHSGCGKSTLLNLISGLAQPTSGGVILEGKQ--ITEPGPDR----MVVFQNYSLLPWLTVRENI 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 101 ALG-------LSTGISAAEIEREIRLLGEKYGLEVDPAsvvmELSMGERQRVEILRALMTKPKLLILDEPTSVLTPQAVR 173
Cdd:TIGR01184  76 ALAvdrvlpdLSKSERRAIVEEHIALVGLTEAADKRPG----QLSGGMKQRVAIARALSIRPKVLLLDEPFGALDALTRG 151

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 2549828669 174 KLFKTLHQLSSE-GVSILFISHKLDEIRELADRCVVLRAG 212
Cdd:TIGR01184 152 NLQEELMQIWEEhRVTVLMVTHDVDEALLLSDRVVMLTNG 191

ABCC_ATM1_transporter

cd03253

ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ...

5-215

1.75e-28

ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213220 [Multi-domain] Cd Length: 236 Bit Score: 113.09 E-value: 1.75e-28

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   5 LSLRNITKRY-PGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQARElGIAM 83
Cdd:cd03253     1 IEFENVTFAYdPGRPVLKDVSFTIPAGKKVAIVGPSGSGKSTILRLLFRFYDVSSGSILIDGQDIREVTLDSLRR-AIGV 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  84 VHQHFALFDTlSVTENVALG--------LSTGISAAEIEREIRLLGEKYglevdpASVVME----LSMGERQRVEILRAL 151
Cdd:cd03253    80 VPQDTVLFND-TIGYNIRYGrpdatdeeVIEAAKAAQIHDKIMRFPDGY------DTIVGErglkLSGGEKQRVAIARAI 152

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2549828669 152 MTKPKLLILDEPTSVLTPQAVRKLFKTLHQLsSEGVSILFISHKLDEIRElADRCVVLRAGKVV 215
Cdd:cd03253   153 LKNPPILLLDEATSALDTHTEREIQAALRDV-SKGRTTIVIAHRLSTIVN-ADKIIVLKDGRIV 214

PhnL

COG4778

Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion ...

1-212

1.99e-28

Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion transport and metabolism];

Pssm-ID: 443809 [Multi-domain] Cd Length: 229 Bit Score: 112.53 E-value: 1.99e-28

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   1 MTPRLSLRNITK----------RYPGItanDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDgHPLGV 70
Cdd:COG4778     1 MTTLLEVENLSKtftlhlqggkRLPVL---DGVSFSVAAGECVALTGPSGAGKSTLLKCIYGNYLPDSGSILVR-HDGGW 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  71 ETPAQA--------RELGIAMVHQHfalfdtLSV-----TENV---ALgLSTGISAAEIEREIRLLGEKYGL-----EVD 129
Cdd:COG4778    77 VDLAQAspreilalRRRTIGYVSQF------LRViprvsALDVvaePL-LERGVDREEARARARELLARLNLperlwDLP 149

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 130 PASvvmeLSMGERQRVEILRALMTKPKLLILDEPTSVLTP---QAVRKLfktLHQLSSEGVSILFISHKLDEIRELADRC 206
Cdd:COG4778   150 PAT----FSGGEQQRVNIARGFIADPPLLLLDEPTASLDAanrAVVVEL---IEEAKARGTAIIGIFHDEEVREAVADRV 222


                  ....*.
gi 2549828669 207 VVLRAG 212
Cdd:COG4778   223 VDVTPF 228

thiQ

PRK10771

thiamine ABC transporter ATP-binding protein ThiQ;

5-215

2.04e-28

thiamine ABC transporter ATP-binding protein ThiQ;

Pssm-ID: 182716 [Multi-domain] Cd Length: 232 Bit Score: 112.75 E-value: 2.04e-28

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   5 LSLRNITKRYPGITAndHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQaRElgIAMV 84
Cdd:PRK10771    2 LKLTDITWLYHHLPM--RFDLTVERGERVAILGPSGAGKSTLLNLIAGFLTPASGSLTLNGQDHTTTPPSR-RP--VSML 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  85 HQHFALFDTLSVTENVALGLSTGIS-AAEIEREIRLLGEKYGLEVDPASVVMELSMGERQRVEILRALMTKPKLLILDEP 163
Cdd:PRK10771   77 FQENNLFSHLTVAQNIGLGLNPGLKlNAAQREKLHAIARQMGIEDLLARLPGQLSGGQRQRVALARCLVREQPILLLDEP 156

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2549828669 164 TSVLTPQAVRKLFKTLHQLSSE-GVSILFISHKLDEIRELADRCVVLRAGKVV 215
Cdd:PRK10771  157 FSALDPALRQEMLTLVSQVCQErQLTLLMVSHSLEDAARIAPRSLVVADGRIA 209

PRK15134

microcin C ABC transporter ATP-binding protein YejF; Provisional

23-215

4.58e-28

microcin C ABC transporter ATP-binding protein YejF; Provisional

Pssm-ID: 237917 [Multi-domain] Cd Length: 529 Bit Score: 117.50 E-value: 4.58e-28

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  23 VSLDIAPGEVLAILGENGAGKST----LMKIIygaarPDEGEISFDGHPLGVETPAQAREL--GIAMVHQ--HFALFDTL 94
Cdd:PRK15134  305 ISFTLRPGETLGLVGESGSGKSTtglaLLRLI-----NSQGEIWFDGQPLHNLNRRQLLPVrhRIQVVFQdpNSSLNPRL 379

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  95 SVTENVALGLST---GISAAEIEREIRLLGEKYGLevDPAS---VVMELSMGERQRVEILRALMTKPKLLILDEPTSVL- 167
Cdd:PRK15134  380 NVLQIIEEGLRVhqpTLSAAQREQQVIAVMEEVGL--DPETrhrYPAEFSGGQRQRIAIARALILKPSLIILDEPTSSLd 457

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 2549828669 168 -TPQA-VRKLFKTLHQlsSEGVSILFISHKLDEIRELADRCVVLRAGKVV 215
Cdd:PRK15134  458 kTVQAqILALLKSLQQ--KHQLAYLFISHDLHVVRALCHQVIVLRQGEVV 505

PRK10762

D-ribose transporter ATP binding protein; Provisional

4-235

4.93e-28

D-ribose transporter ATP binding protein; Provisional

Pssm-ID: 236755 [Multi-domain] Cd Length: 501 Bit Score: 117.03 E-value: 4.93e-28

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   4 RLSLRNITKryPGItanDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQARELGIAM 83
Cdd:PRK10762  257 RLKVDNLSG--PGV---NDVSFTLRKGEILGVSGLMGAGRTELMKVLYGALPRTSGYVTLDGHEVVTRSPQDGLANGIVY 331

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  84 V---HQHFALFDTLSVTENVALGLSTGIS--------AAE---IEREIRLLGEKyglevDPA--SVVMELSMGERQRVEI 147
Cdd:PRK10762  332 IsedRKRDGLVLGMSVKENMSLTALRYFSraggslkhADEqqaVSDFIRLFNIK-----TPSmeQAIGLLSGGNQQKVAI 406

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 148 LRALMTKPKLLILDEPTSVLTPQAVRKLFKTLHQLSSEGVSILFISHKLDEIRELADRCVVLRAGKVVASVDPKAESEEN 227
Cdd:PRK10762  407 ARGLMTRPKVLILDEPTRGVDVGAKKEIYQLINQFKAEGLSIILVSSEMPEVLGMSDRILVMHEGRISGEFTREQATQEK 486


                  ....*...
gi 2549828669 228 LARLMIGN 235
Cdd:PRK10762  487 LMAAAVGK 494

ABCC_Glucan_exporter_like

cd03254

ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ...

4-215

1.17e-27

ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213221 [Multi-domain] Cd Length: 229 Bit Score: 110.39 E-value: 1.17e-27

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   4 RLSLRNITKRY-PGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQARELgIA 82
Cdd:cd03254     2 EIEFENVNFSYdEKKPVLKDINFSIKPGETVAIVGPTGAGKTTLINLLMRFYDPQKGQILIDGIDIRDISRKSLRSM-IG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  83 MVHQHFALFDTlSVTENVALGLSTgISAAEIEREIRLLGEKYGLEVDP---ASVVME----LSMGERQRVEILRALMTKP 155
Cdd:cd03254    81 VVLQDTFLFSG-TIMENIRLGRPN-ATDEEVIEAAKEAGAHDFIMKLPngyDTVLGEnggnLSQGERQLLAIARAMLRDP 158

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2549828669 156 KLLILDEPTSVLTP-------QAVRKLFKtlhqlsseGVSILFISHKLDEIRElADRCVVLRAGKVV 215
Cdd:cd03254   159 KILILDEATSNIDTetekliqEALEKLMK--------GRTSIIIAHRLSTIKN-ADKILVLDDGKII 216

cbiO

PRK13650

energy-coupling factor transporter ATPase;

1-222

1.31e-27

energy-coupling factor transporter ATPase;

Pssm-ID: 184209 [Multi-domain] Cd Length: 279 Bit Score: 111.75 E-value: 1.31e-27

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   1 MTPRLSLRNITKRYPGITAN---DHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQAR 77
Cdd:PRK13650    1 MSNIIEVKNLTFKYKEDQEKytlNDVSFHVKQGEWLSIIGHNGSGKSTTVRLIDGLLEAESGQIIIDGDLLTEENVWDIR 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  78 ELgIAMVHQH-FALFDTLSVTENVALGL-STGISAAE----IEREIRLLGEKYGLEVDPAsvvmELSMGERQRVEILRAL 151
Cdd:PRK13650   81 HK-IGMVFQNpDNQFVGATVEDDVAFGLeNKGIPHEEmkerVNEALELVGMQDFKEREPA----RLSGGQKQRVAIAGAV 155

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2549828669 152 MTKPKLLILDEPTSVLTPQAVRKLFKTLHQLSSE-GVSILFISHKLDEIrELADRCVVLRAGKVVASVDPKA 222
Cdd:PRK13650  156 AMRPKIIILDEATSMLDPEGRLELIKTIKGIRDDyQMTVISITHDLDEV-ALSDRVLVMKNGQVESTSTPRE 226

SufC

COG0396

Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, ...

23-220

1.48e-27

Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, chaperones];

Pssm-ID: 440165 [Multi-domain] Cd Length: 245 Bit Score: 110.54 E-value: 1.48e-27

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  23 VSLDIAPGEVLAILGENGAGKSTLMKIIYG--AARPDEGEISFDGHPLGVETPAQ-AReLGIAMVHQHFALFDTLSVTE- 98
Cdd:COG0396    19 VNLTIKPGEVHAIMGPNGSGKSTLAKVLMGhpKYEVTSGSILLDGEDILELSPDErAR-AGIFLAFQYPVEIPGVSVSNf 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  99 -NVALGLSTG--ISAAEIEREIRLLGEKYGLEVDPA--SVVMELSMGERQRVEILRALMTKPKLLILDEPTSVLTPQAVR 173
Cdd:COG0396    98 lRTALNARRGeeLSAREFLKLLKEKMKELGLDEDFLdrYVNEGFSGGEKKRNEILQMLLLEPKLAILDETDSGLDIDALR 177

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 2549828669 174 KLFKTLHQLSSEGVSILFISHK---LDEIRelADRCVVLRAGKVVASVDP 220
Cdd:COG0396   178 IVAEGVNKLRSPDRGILIITHYqriLDYIK--PDFVHVLVDGRIVKSGGK 225

cbiO

PRK13636

cobalt transporter ATP-binding subunit; Provisional

5-221

1.50e-27

cobalt transporter ATP-binding subunit; Provisional

Pssm-ID: 184196 [Multi-domain] Cd Length: 283 Bit Score: 111.86 E-value: 1.50e-27

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   5 LSLRNITKRYP-GITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPA--QARElGI 81
Cdd:PRK13636    6 LKVEELNYNYSdGTHALKGININIKKGEVTAILGGNGAGKSTLFQNLNGILKPSSGRILFDGKPIDYSRKGlmKLRE-SV 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  82 AMVHQH--FALFdTLSVTENVALG-LSTGISAAEIEREIRLLGEKYGLEVDPASVVMELSMGERQRVEILRALMTKPKLL 158
Cdd:PRK13636   85 GMVFQDpdNQLF-SASVYQDVSFGaVNLKLPEDEVRKRVDNALKRTGIEHLKDKPTHCLSFGQKKRVAIAGVLVMEPKVL 163

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2549828669 159 ILDEPTSVLTPQAVRKLFKTLHQLSSE-GVSILFISHKLDEIRELADRCVVLRAGKVVASVDPK 221
Cdd:PRK13636  164 VLDEPTAGLDPMGVSEIMKLLVEMQKElGLTIIIATHDIDIVPLYCDNVFVMKEGRVILQGNPK 227

AztA

NF040873

zinc ABC transporter ATP-binding protein AztA;

13-209

1.69e-27

zinc ABC transporter ATP-binding protein AztA;

Pssm-ID: 468810 [Multi-domain] Cd Length: 191 Bit Score: 108.86 E-value: 1.69e-27

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  13 RYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEIsfdghplgvetpAQARELGIAMVHQHFALFD 92
Cdd:NF040873    1 GYGGRPVLHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLRPTSGTV------------RRAGGARVAYVPQRSEVPD 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  93 TLSVT--ENVALGL---------STGISAAEIEREIRLLGEKyGLEVDPASvvmELSMGERQRVEILRALMTKPKLLILD 161
Cdd:NF040873   69 SLPLTvrDLVAMGRwarrglwrrLTRDDRAAVDDALERVGLA-DLAGRQLG---ELSGGQRQRALLAQGLAQEADLLLLD 144

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 2549828669 162 EPTSVLTPQAVRKLFKTLHQLSSEGVSILFISHKLDEIReLADRCVVL 209
Cdd:NF040873  145 EPTTGLDAESRERIIALLAEEHARGATVVVVTHDLELVR-RADPCVLL 191

nikE

PRK10419

nickel ABC transporter ATP-binding protein NikE;

5-215

2.51e-27

nickel ABC transporter ATP-binding protein NikE;

Pssm-ID: 236689 [Multi-domain] Cd Length: 268 Bit Score: 110.55 E-value: 2.51e-27

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   5 LSLRNITKRY---------PGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQ 75
Cdd:PRK10419    4 LNVSGLSHHYahgglsgkhQHQTVLNNVSLSLKSGETVALLGRSGCGKSTLARLLVGLESPSQGNVSWRGEPLAKLNRAQ 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  76 AREL--GIAMVHQhfalfDTLS-------VTENVALGLS--TGISAAEIEREIRLLGEKYGLEVDPAS-VVMELSMGERQ 143
Cdd:PRK10419   84 RKAFrrDIQMVFQ-----DSISavnprktVREIIREPLRhlLSLDKAERLARASEMLRAVDLDDSVLDkRPPQLSGGQLQ 158

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2549828669 144 RVEILRALMTKPKLLILDEPTS----VLTPQAVRKLFKTLHQLsseGVSILFISHKLDEIRELADRCVVLRAGKVV 215
Cdd:PRK10419  159 RVCLARALAVEPKLLILDEAVSnldlVLQAGVIRLLKKLQQQF---GTACLFITHDLRLVERFCQRVMVMDNGQIV 231

PRK11000

maltose/maltodextrin ABC transporter ATP-binding protein MalK;

6-214

3.56e-27

maltose/maltodextrin ABC transporter ATP-binding protein MalK;

Pssm-ID: 182893 [Multi-domain] Cd Length: 369 Bit Score: 112.43 E-value: 3.56e-27

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   6 SLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAqarELGIAMVH 85
Cdd:PRK11000    5 TLRNVTKAYGDVVISKDINLDIHEGEFVVFVGPSGCGKSTLLRMIAGLEDITSGDLFIGEKRMNDVPPA---ERGVGMVF 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  86 QHFALFDTLSVTENVALGLS-TGISAAEIEREI----RLLGEKYGLEVDPAsvvmELSMGERQRVEILRALMTKPKLLIL 160
Cdd:PRK11000   82 QSYALYPHLSVAENMSFGLKlAGAKKEEINQRVnqvaEVLQLAHLLDRKPK----ALSGGQRQRVAIGRTLVAEPSVFLL 157

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2549828669 161 DEPTSVLTpQAVR--------KLFKTLhqlsseGVSILFISHKLDEIRELADRCVVLRAGKV 214
Cdd:PRK11000  158 DEPLSNLD-AALRvqmrieisRLHKRL------GRTMIYVTHDQVEAMTLADKIVVLDAGRV 212

thiQ

TIGR01277

thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ...

24-214

3.74e-27

thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ATPase subunit ThiQ of the ThiBPQ thiamine (and thiamine pyrophosphate) ABC transporter in several Proteobacteria. This protein is found so far only in Proteobacteria, and is found in complete genomes only if the ThiB and ThiP subunits are also found. [Transport and binding proteins, Other]

Pssm-ID: 130344 [Multi-domain] Cd Length: 213 Bit Score: 108.80 E-value: 3.74e-27

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  24 SLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQARelgIAMVHQHFALFDTLSVTENVALG 103
Cdd:TIGR01277  18 DLNVADGEIVAIMGPSGAGKSTLLNLIAGFIEPASGSIKVNDQSHTGLAPYQRP---VSMLFQENNLFAHLTVRQNIGLG 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 104 LSTGISAAEIERE-IRLLGEKYGLEVDPASVVMELSMGERQRVEILRALMTKPKLLILDEPTSVLTPQAVRKLFKTLHQL 182
Cdd:TIGR01277  95 LHPGLKLNAEQQEkVVDAAQQVGIADYLDRLPEQLSGGQRQRVALARCLVRPNPILLLDEPFSALDPLLREEMLALVKQL 174

                         170       180       190
                  ....*....|....*....|....*....|...
gi 2549828669 183 SSE-GVSILFISHKLDEIRELADRCVVLRAGKV 214
Cdd:TIGR01277 175 CSErQRTLLMVTHHLSDARAIASQIAVVSQGKI 207

ArpD

COG4618

ABC-type protease/lipase transport system, ATPase and permease components [Intracellular ...

4-232

9.08e-27

ABC-type protease/lipase transport system, ATPase and permease components [Intracellular trafficking, secretion, and vesicular transport];

Pssm-ID: 443660 [Multi-domain] Cd Length: 563 Bit Score: 113.69 E-value: 9.08e-27

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   4 RLSLRNITKRYPG----ITANdhVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPaqaREL 79
Cdd:COG4618   330 RLSVENLTVVPPGskrpILRG--VSFSLEPGEVLGVIGPSGSGKSTLARLLVGVWPPTAGSVRLDGADLSQWDR---EEL 404

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  80 G--IAMVHQHFALFDTlSVTENVA-LGlstGISAAEIEREIRLLG---------EKYGLEVDPASVVmeLSMGERQRVEI 147
Cdd:COG4618   405 GrhIGYLPQDVELFDG-TIAENIArFG---DADPEKVVAAAKLAGvhemilrlpDGYDTRIGEGGAR--LSGGQRQRIGL 478

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 148 LRALMTKPKLLILDEPTSVLTPQAVRKLFKTLHQLSSEGVSILFISHKLDEIRElADRCVVLRAGKVVAsVDPKaesEEN 227
Cdd:COG4618   479 ARALYGDPRLVVLDEPNSNLDDEGEAALAAAIRALKARGATVVVITHRPSLLAA-VDKLLVLRDGRVQA-FGPR---DEV 553


                  ....*
gi 2549828669 228 LARLM 232
Cdd:COG4618   554 LARLA 558

lolD

PRK11629

lipoprotein-releasing ABC transporter ATP-binding protein LolD;

2-205

1.01e-26

lipoprotein-releasing ABC transporter ATP-binding protein LolD;

Pssm-ID: 183244 [Multi-domain] Cd Length: 233 Bit Score: 107.98 E-value: 1.01e-26

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   2 TPRLSLRNITKRY-PGITAND---HVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLG-VETPAQA 76
Cdd:PRK11629    3 KILLQCDNLCKRYqEGSVQTDvlhNVSFSIGEGEMMAIVGSSGSGKSTLLHLLGGLDTPTSGDVIFNGQPMSkLSSAAKA 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  77 ----RELGiaMVHQHFALFDTLSVTENVALGLSTG-ISAAEIEREIRLLGEKYGLEVDPASVVMELSMGERQRVEILRAL 151
Cdd:PRK11629   83 elrnQKLG--FIYQFHHLLPDFTALENVAMPLLIGkKKPAEINSRALEMLAAVGLEHRANHRPSELSGGERQRVAIARAL 160

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2549828669 152 MTKPKLLILDEPTSVLTPQAVRKLFKTLHQLS-SEGVSILFISHKLdeirELADR 205
Cdd:PRK11629  161 VNNPRLVLADEPTGNLDARNADSIFQLLGELNrLQGTAFLVVTHDL----QLAKR 211

PRK10895

lipopolysaccharide ABC transporter ATP-binding protein; Provisional

4-236

1.45e-26

lipopolysaccharide ABC transporter ATP-binding protein; Provisional

Pssm-ID: 182817 [Multi-domain] Cd Length: 241 Bit Score: 107.67 E-value: 1.45e-26

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   4 RLSLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVeTPAQAREL-GIA 82
Cdd:PRK10895    3 TLTAKNLAKAYKGRRVVEDVSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRDAGNIIIDDEDISL-LPLHARARrGIG 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  83 MVHQHFALFDTLSVTENVALGLSTGISAAEIEREIRL--LGEKYGLEVDPASVVMELSMGERQRVEILRALMTKPKLLIL 160
Cdd:PRK10895   82 YLPQEASIFRRLSVYDNLMAVLQIRDDLSAEQREDRAneLMEEFHIEHLRDSMGQSLSGGERRRVEIARALAANPKFILL 161

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2549828669 161 DEPTSVLTPQAVRKLFKTLHQLSSEGVSILFISHKLDEIRELADRCVVLRAGKVVASVDPKA-ESEENLARLMIGND 236
Cdd:PRK10895  162 DEPFAGVDPISVIDIKRIIEHLRDSGLGVLITDHNVRETLAVCERAYIVSQGHLIAHGTPTEiLQDEHVKRVYLGED 238

Uup

COG0488

ATPase components of ABC transporters with duplicated ATPase domains [General function ...

5-215

2.37e-26

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];

Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 112.08 E-value: 2.37e-26

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   5 LSLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFdGHplGVEtpaqarelgIAMV 84
Cdd:COG0488   316 LELEGLSKSYGDKTLLDDLSLRIDRGDRIGLIGPNGAGKSTLLKLLAGELEPDSGTVKL-GE--TVK---------IGYF 383

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  85 HQHFALFD-TLSVTENVALGLSTGisaaeIEREIRLLGEKYGLEVD----PASVvmeLSMGERQRVEILRALMTKPKLLI 159
Cdd:COG0488   384 DQHQEELDpDKTVLDELRDGAPGG-----TEQEVRGYLGRFLFSGDdafkPVGV---LSGGEKARLALAKLLLSPPNVLL 455

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2549828669 160 LDEPTSVLTPQavrklfkTLHQLSS-----EGvSILFISHklDE--IRELADRCVVLRAGKVV 215
Cdd:COG0488   456 LDEPTNHLDIE-------TLEALEEalddfPG-TVLLVSH--DRyfLDRVATRILEFEDGGVR 508

ATM1

COG5265

ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components ...

21-215

2.52e-26

ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones];

Pssm-ID: 444078 [Multi-domain] Cd Length: 605 Bit Score: 112.61 E-value: 2.52e-26

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  21 DHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQARElGIAMVHQHFALF-DTLSvtEN 99
Cdd:COG5265   375 KGVSFEVPAGKTVAIVGPSGAGKSTLARLLFRFYDVTSGRILIDGQDIRDVTQASLRA-AIGIVPQDTVLFnDTIA--YN 451

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 100 VALGlSTGISAAEIEREIRL---------LGEKYglevdpASVVME----LSMGERQRVEILRALMTKPKLLILDEPTSV 166
Cdd:COG5265   452 IAYG-RPDASEEEVEAAARAaqihdfiesLPDGY------DTRVGErglkLSGGEKQRVAIARTLLKNPPILIFDEATSA 524

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2549828669 167 L---TPQAVRklfKTLHQLsSEGVSILFISHKLDEIRElADRCVVLRAGKVV 215
Cdd:COG5265   525 LdsrTERAIQ---AALREV-ARGRTTLVIAHRLSTIVD-ADEILVLEAGRIV 571

ABCC_TAP

cd03248

ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; ...

4-214

4.37e-26

ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; TAP (Transporter Associated with Antigen Processing) is essential for peptide delivery from the cytosol into the lumen of the endoplasmic reticulum (ER), where these peptides are loaded on major histocompatibility complex (MHC) I molecules. Loaded MHC I leave the ER and display their antigenic cargo on the cell surface to cytotoxic T cells. Subsequently, virus-infected or malignantly transformed cells can be eliminated. TAP belongs to the large family of ATP-binding cassette (ABC) transporters, which translocate a vast variety of solutes across membranes.

Pssm-ID: 213215 [Multi-domain] Cd Length: 226 Bit Score: 106.02 E-value: 4.37e-26

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   4 RLSLRNITKRYPgiTANDH-----VSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQARE 78
Cdd:cd03248    11 IVKFQNVTFAYP--TRPDTlvlqdVSFTLHPGEVTALVGPSGSGKSTVVALLENFYQPQGGQVLLDGKPISQYEHKYLHS 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  79 LgIAMVHQHFALFdTLSVTENVALGLST--------GISAAEIEREIRLLGEKYGLEVDPASVvmELSMGERQRVEILRA 150
Cdd:cd03248    89 K-VSLVGQEPVLF-ARSLQDNIAYGLQScsfecvkeAAQKAHAHSFISELASGYDTEVGEKGS--QLSGGQKQRVAIARA 164

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2549828669 151 LMTKPKLLILDEPTSVLTPQAvRKLFKTLHQLSSEGVSILFISHKLDEIrELADRCVVLRAGKV 214
Cdd:cd03248   165 LIRNPQVLILDEATSALDAES-EQQVQQALYDWPERRTVLVIAHRLSTV-ERADQILVLDGGRI 226

ABC_FeS_Assembly

cd03217

ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of ...

23-221

7.25e-26

ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.

Pssm-ID: 213184 [Multi-domain] Cd Length: 200 Bit Score: 104.53 E-value: 7.25e-26

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  23 VSLDIAPGEVLAILGENGAGKSTLMKIIYG--AARPDEGEISFDGHPLGVETPAQARELGIAMVHQHFALFdtlsvtenv 100
Cdd:cd03217    19 VNLTIKKGEVHALMGPNGSGKSTLAKTIMGhpKYEVTEGEILFKGEDITDLPPEERARLGIFLAFQYPPEI--------- 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 101 alglsTGISAAEIereIRLLGEKyglevdpasvvmeLSMGERQRVEILRALMTKPKLLILDEPTSVLTPQAVRKLFKTLH 180
Cdd:cd03217    90 -----PGVKNADF---LRYVNEG-------------FSGGEKKRNEILQLLLLEPDLAILDEPDSGLDIDALRLVAEVIN 148

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 2549828669 181 QLSSEGVSILFISHK---LDEIRelADRCVVLRAGKVVASVDPK 221
Cdd:cd03217   149 KLREEGKSVLIITHYqrlLDYIK--PDRVHVLYDGRIVKSGDKE 190

dppF

PRK11308

dipeptide transporter ATP-binding subunit; Provisional

1-215

8.49e-26

dipeptide transporter ATP-binding subunit; Provisional

Pssm-ID: 236898 [Multi-domain] Cd Length: 327 Bit Score: 107.74 E-value: 8.49e-26

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   1 MTPRLSLRNITKRYP---GI-------TANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGV 70
Cdd:PRK11308    2 QQPLLQAIDLKKHYPvkrGLfkperlvKALDGVSFTLERGKTLAVVGESGCGKSTLARLLTMIETPTGGELYYQGQDLLK 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  71 ETPAQAREL--GIAMVHQHfaLFDTLSVTENVA------LGLSTGISAAEIEREIRLLGEKYGLEVDPASVV--MeLSMG 140
Cdd:PRK11308   82 ADPEAQKLLrqKIQIVFQN--PYGSLNPRKKVGqileepLLINTSLSAAERREKALAMMAKVGLRPEHYDRYphM-FSGG 158

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2549828669 141 ERQRVEILRALMTKPKLLILDEPTSVL--TPQA-VRKLFKTLHQlsSEGVSILFISHKLDEIRELADRCVVLRAGKVV 215
Cdd:PRK11308  159 QRQRIAIARALMLDPDVVVADEPVSALdvSVQAqVLNLMMDLQQ--ELGLSYVFISHDLSVVEHIADEVMVMYLGRCV 234

PRK10908

cell division ATP-binding protein FtsE;

23-219

1.45e-25

cell division ATP-binding protein FtsE;

Pssm-ID: 182829 [Multi-domain] Cd Length: 222 Bit Score: 104.57 E-value: 1.45e-25

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  23 VSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLG----VETPAQARELGiaMVHQHFALFDTLSVTE 98
Cdd:PRK10908   21 VTFHMRPGEMAFLTGHSGAGKSTLLKLICGIERPSAGKIWFSGHDITrlknREVPFLRRQIG--MIFQDHHLLMDRTVYD 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  99 NVALGLS-TGISAAEIEREIRLLGEKYGLEVDPASVVMELSMGERQRVEILRALMTKPKLLILDEPTSVLTPQAVRKLFK 177
Cdd:PRK10908   99 NVAIPLIiAGASGDDIRRRVSAALDKVGLLDKAKNFPIQLSGGEQQRVGIARAVVNKPAVLLADEPTGNLDDALSEGILR 178

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 2549828669 178 TLHQLSSEGVSILFISHKLDEIRELADRCVVLRAGKVVASVD 219
Cdd:PRK10908  179 LFEEFNRVGVTVLMATHDIGLISRRSYRMLTLSDGHLHGGVG 220

xylG

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ...

5-217

2.82e-25

Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 108.76 E-value: 2.82e-25

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   5 LSLRNITKRY---PGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPD-EGEISFDGHPLGVETPAQARELG 80
Cdd:TIGR02633 258 LEARNLTCWDvinPHRKRVDDVSFSLRRGEILGVAGLVGAGRTELVQALFGAYPGKfEGNVFINGKPVDIRNPAQAIRAG 337

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  81 IAMV---HQHFALFDTLSVTENVAL-------GLSTGISAAE---IEREIRLLGEKyglEVDPASVVMELSMGERQRVEI 147
Cdd:TIGR02633 338 IAMVpedRKRHGIVPILGVGKNITLsvlksfcFKMRIDAAAElqiIGSAIQRLKVK---TASPFLPIGRLSGGNQQKAVL 414

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 148 LRALMTKPKLLILDEPTSVLTPQAVRKLFKTLHQLSSEGVSILFISHKLDEIRELADRCVVLRAGKVVAS 217
Cdd:TIGR02633 415 AKMLLTNPRVLILDEPTRGVDVGAKYEIYKLINQLAQEGVAIIVVSSELAEVLGLSDRVLVIGEGKLKGD 484

PRK10261

glutathione transporter ATP-binding protein; Provisional

5-469

4.64e-25

glutathione transporter ATP-binding protein; Provisional

Pssm-ID: 182342 [Multi-domain] Cd Length: 623 Bit Score: 108.79 E-value: 4.64e-25

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   5 LSLRNITKRY----PGITANDHVSLDIAPGEVLAILGENGAGKS----TLMKIIYGAArpdeGEISFDGH---------- 66
Cdd:PRK10261   13 LAVENLNIAFmqeqQKIAAVRNLSFSLQRGETLAIVGESGSGKSvtalALMRLLEQAG----GLVQCDKMllrrrsrqvi 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  67 PLGVETPAQAREL---GIAMVHQH--FALFDTLSVTENVA--LGLSTGISAAEIEREIRLLGEKYGLevdPASVVM---- 135
Cdd:PRK10261   89 ELSEQSAAQMRHVrgaDMAMIFQEpmTSLNPVFTVGEQIAesIRLHQGASREEAMVEAKRMLDQVRI---PEAQTIlsry 165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 136 --ELSMGERQRVEILRALMTKPKLLILDEPTSVL--TPQA-VRKLFKTLHQLSSEGVsiLFISHKLDEIRELADRCVVLR 210
Cdd:PRK10261  166 phQLSGGMRQRVMIAMALSCRPAVLIADEPTTALdvTIQAqILQLIKVLQKEMSMGV--IFITHDMGVVAEIADRVLVMY 243

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 211 AGKVV--ASVD------------------PK--AESEENLAR---LMIGNDP----PTVREGTAKAGEVVFEMRHVSAPG 261
Cdd:PRK10261  244 QGEAVetGSVEqifhapqhpytrallaavPQlgAMKGLDYPRrfpLISLEHPakqePPIEQDTVVDGEPILQVRNLVTRF 323

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 262 STR----------VCGIDNVSLAVRAGEIVGIAGISGNGQA-------RFMAAASGEYLCEADRV--------------- 309
Cdd:PRK10261  324 PLRsgllnrvtreVHAVEKVSFDLWPGETLSLVGESGSGKSttgrallRLVESQGGEIIFNGQRIdtlspgklqalrrdi 403

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 310 -LLFNSPVGELDtharrisglryvPEQRLGHAAVPELSLtantyltgdslvrSGFILRDRARSFANLVIERFHVKTPNAE 388
Cdd:PRK10261  404 qFIFQDPYASLD------------PRQTVGDSIMEPLRV-------------HGLLPGKAAAARVAWLLERVGLLPEHAW 458

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 389 KAAGSLSGGNLQKFIMGREILNRPRVLLVHQPTWGVDVGAAAVIRNSLIRL-RDDGAAIIVVSEEIDELFEISDRIAVMY 467
Cdd:PRK10261  459 RYPHEFSGGQRQRICIARALALNPKVIIADEAVSALDVSIRGQIINLLLDLqRDFGIAYLFISHDMAVVERISHRVAVMY 538


                  ..
gi 2549828669 468 RG 469
Cdd:PRK10261  539 LG 540

cbiO

PRK13637

energy-coupling factor transporter ATPase;

19-221

6.67e-25

energy-coupling factor transporter ATPase;

Pssm-ID: 237455 [Multi-domain] Cd Length: 287 Bit Score: 104.36 E-value: 6.67e-25

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  19 ANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPL---GVETPAQARELGIAMVHQHFALFDTlS 95
Cdd:PRK13637   22 ALDNVNIEIEDGEFVGLIGHTGSGKSTLIQHLNGLLKPTSGKIIIDGVDItdkKVKLSDIRKKVGLVFQYPEYQLFEE-T 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  96 VTENVALGLST-GISAAEIEREIRLLGEKYGLEVD------PasvvMELSMGERQRVEILRALMTKPKLLILDEPTSVLT 168
Cdd:PRK13637  101 IEKDIAFGPINlGLSEEEIENRVKRAMNIVGLDYEdykdksP----FELSGGQKRRVAIAGVVAMEPKILILDEPTAGLD 176

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2549828669 169 PQAVRKLFKTLHQLSSE-GVSILFISHKLDEIRELADRCVVLRAGKVVASVDPK 221
Cdd:PRK13637  177 PKGRDEILNKIKELHKEyNMTIILVSHSMEDVAKLADRIIVMNKGKCELQGTPR 230

PvdE

COG4615

ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion ...

4-216

9.54e-25

ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion transport and metabolism];

Pssm-ID: 443659 [Multi-domain] Cd Length: 547 Bit Score: 107.58 E-value: 9.54e-25

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   4 RLSLRNITKRYPGITANDH-----VSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQARE 78
Cdd:COG4615   327 TLELRGVTYRYPGEDGDEGftlgpIDLTIRRGELVFIVGGNGSGKSTLAKLLTGLYRPESGEILLDGQPVTADNREAYRQ 406

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  79 LgIAMVHQHFALFDTLsvtenvaLGLSTGISAAEIEREIRLLG--EKYGLEVDPASVVmELSMGERQRVEILRALMTKPK 156
Cdd:COG4615   407 L-FSAVFSDFHLFDRL-------LGLDGEADPARARELLERLEldHKVSVEDGRFSTT-DLSQGQRKRLALLVALLEDRP 477

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 157 LLILDE------PTsvltpqaVRKLFKT--LHQLSSEGVSILFISHklDEiR--ELADRCVVLRAGKVVA 216
Cdd:COG4615   478 ILVFDEwaadqdPE-------FRRVFYTelLPELKARGKTVIAISH--DD-RyfDLADRVLKMDYGKLVE 537

PRK10247

putative ABC transporter ATP-binding protein YbbL; Provisional

2-213

1.04e-24

putative ABC transporter ATP-binding protein YbbL; Provisional

Pssm-ID: 182331 [Multi-domain] Cd Length: 225 Bit Score: 102.10 E-value: 1.04e-24

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   2 TPRLSLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQARElGI 81
Cdd:PRK10247    5 SPLLQLQNVGYLAGDAKILNNISFSLRAGEFKLITGPSGCGKSTLLKIVASLISPTSGTLLFEGEDISTLKPEIYRQ-QV 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  82 AMVHQHFALF-DTlsVTENVALGLSTGISAAEIEREIRLLgEKYGLevdPASV----VMELSMGERQRVEILRALMTKPK 156
Cdd:PRK10247   84 SYCAQTPTLFgDT--VYDNLIFPWQIRNQQPDPAIFLDDL-ERFAL---PDTIltknIAELSGGEKQRISLIRNLQFMPK 157

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 157 LLILDEPTSVLTPQAVRKLFKTLHQLSSE-GVSILFISHKLDEIRElADRCVVL--RAGK 213
Cdd:PRK10247  158 VLLLDEITSALDESNKHNVNEIIHRYVREqNIAVLWVTHDKDEINH-ADKVITLqpHAGE 216

ABC_KpsT_Wzt

cd03220

ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ...

12-216

2.11e-24

ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.

Pssm-ID: 213187 [Multi-domain] Cd Length: 224 Bit Score: 101.07 E-value: 2.11e-24

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  12 KRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGhplgveTPAQARELGIAMVhqhfalf 91
Cdd:cd03220    30 GEVGEFWALKDVSFEVPRGERIGLIGRNGAGKSTLLRLLAGIYPPDSGTVTVRG------RVSSLLGLGGGFN------- 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  92 DTLSVTENVAL-GLSTGISAAEIEREIRL------LGEKYGLevdPasvVMELSMGERQRVEILRALMTKPKLLILDEPT 164
Cdd:cd03220    97 PELTGRENIYLnGRLLGLSRKEIDEKIDEiiefseLGDFIDL---P---VKTYSSGMKARLAFAIATALEPDILLIDEVL 170

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2549828669 165 SVLTPQAVRKLFKTLHQLSSEGVSILFISHKLDEIRELADRCVVLRAGKVVA 216
Cdd:cd03220   171 AVGDAAFQEKCQRRLRELLKQGKTVILVSHDPSSIKRLCDRALVLEKGKIRF 222

araG

PRK11288

L-arabinose ABC transporter ATP-binding protein AraG;

4-231

4.45e-24

L-arabinose ABC transporter ATP-binding protein AraG;

Pssm-ID: 183077 [Multi-domain] Cd Length: 501 Bit Score: 104.99 E-value: 4.45e-24

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   4 RLSLRNITKryPGITANdhVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQARELGIAM 83
Cdd:PRK11288  257 RLRLDGLKG--PGLREP--ISFSVRAGEIVGLFGLVGAGRSELMKLLYGATRRTAGQVYLDGKPIDIRSPRDAIRAGIML 332

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  84 V---HQHFALFDTLSVTENVALG-----------LSTGISAAEIEREIRLLGEKyglEVDPASVVMELSMGERQRVEILR 149
Cdd:PRK11288  333 CpedRKAEGIIPVHSVADNINISarrhhlragclINNRWEAENADRFIRSLNIK---TPSREQLIMNLSGGNQQKAILGR 409

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 150 ALMTKPKLLILDEPTSVLTPQAVRKLFKTLHQLSSEGVSILFISHKLDEIRELADRCVVLRAGKVVASVDPKAESEENLA 229
Cdd:PRK11288  410 WLSEDMKVILLDEPTRGIDVGAKHEIYNVIYELAAQGVAVLFVSSDLPEVLGVADRIVVMREGRIAGELAREQATERQAL 489


                  ..
gi 2549828669 230 RL 231
Cdd:PRK11288  490 SL 491

cbiO

PRK13647

cobalt transporter ATP-binding subunit; Provisional

7-229

5.03e-24

cobalt transporter ATP-binding subunit; Provisional

Pssm-ID: 237457 [Multi-domain] Cd Length: 274 Bit Score: 101.35 E-value: 5.03e-24

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   7 LRNITKRYP-GITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQARELgIAMVH 85
Cdd:PRK13647    7 VEDLHFRYKdGTKALKGLSLSIPEGSKTALLGPNGAGKSTLLLHLNGIYLPQRGRVKVMGREVNAENEKWVRSK-VGLVF 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  86 QH-----FALfdtlSVTENVALG-LSTGISAAEIEREIRLLGEKYGLEVDPASVVMELSMGERQRVEILRALMTKPKLLI 159
Cdd:PRK13647   86 QDpddqvFSS----TVWDDVAFGpVNMGLDKDEVERRVEEALKAVRMWDFRDKPPYHLSYGQKKRVAIAGVLAMDPDVIV 161

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 160 LDEPTSVLTPQAVRKLFKTLHQLSSEGVSILFISHKLDEIRELADRCVVLRAGKVVASVDPKAESEENLA 229
Cdd:PRK13647  162 LDEPMAYLDPRGQETLMEILDRLHNQGKTVIVATHDVDLAAEWADQVIVLKEGRVLAEGDKSLLTDEDIV 231

PRK13633

energy-coupling factor transporter ATPase;

18-242

5.83e-24

energy-coupling factor transporter ATPase;

Pssm-ID: 237453 [Multi-domain] Cd Length: 280 Bit Score: 101.32 E-value: 5.83e-24

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  18 TANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGhplgVETPAQARELGI----AMVHQH--FALF 91
Cdd:PRK13633   24 LALDDVNLEVKKGEFLVILGRNGSGKSTIAKHMNALLIPSEGKVYVDG----LDTSDEENLWDIrnkaGMVFQNpdNQIV 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  92 DTLsVTENVALGLST-GISAAEIEREIRLLGEKYGLEVDPASVVMELSMGERQRVEILRALMTKPKLLILDEPTSVLTPQ 170
Cdd:PRK13633  100 ATI-VEEDVAFGPENlGIPPEEIRERVDESLKKVGMYEYRRHAPHLLSGGQKQRVAIAGILAMRPECIIFDEPTAMLDPS 178

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2549828669 171 AVRKLFKTLHQLSSE-GVSILFISHKLDEIRElADRCVVLRAGKVVASVDPKAESEENLARLMIGNDPPTVRE 242
Cdd:PRK13633  179 GRREVVNTIKELNKKyGITIILITHYMEEAVE-ADRIIVMDSGKVVMEGTPKEIFKEVEMMKKIGLDVPQVTE 250

PRK10070

proline/glycine betaine ABC transporter ATP-binding protein ProV;

24-220

5.93e-24

proline/glycine betaine ABC transporter ATP-binding protein ProV;

Pssm-ID: 182221 [Multi-domain] Cd Length: 400 Bit Score: 103.57 E-value: 5.93e-24

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  24 SLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQAREL---GIAMVHQHFALFDTLSVTENV 100
Cdd:PRK10070   48 SLAIEEGEIFVIMGLSGSGKSTMVRLLNRLIEPTRGQVLIDGVDIAKISDAELREVrrkKIAMVFQSFALMPHMTVLDNT 127

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 101 ALGLS-TGISAAEIEREIRLLGEKYGLEVDPASVVMELSMGERQRVEILRALMTKPKLLILDEPTSVLTPQAVRKLFKTL 179
Cdd:PRK10070  128 AFGMElAGINAEERREKALDALRQVGLENYAHSYPDELSGGMRQRVGLARALAINPDILLMDEAFSALDPLIRTEMQDEL 207

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 2549828669 180 HQLSSEGV-SILFISHKLDEIRELADRCVVLRAGKVVASVDP 220
Cdd:PRK10070  208 VKLQAKHQrTIVFISHDLDEAMRIGDRIAIMQNGEVVQVGTP 249

BtuD

COG4138

ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism]; ...

23-231

6.45e-24

ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism];

Pssm-ID: 443313 [Multi-domain] Cd Length: 248 Bit Score: 100.30 E-value: 6.45e-24

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  23 VSLDIAPGEVLAILGENGAGKSTLMKIIYGAArPDEGEISFDGHPLG-VETPAQARELgiAMVHQHFALFDTLSVTENVA 101
Cdd:COG4138    15 ISAQVNAGELIHLIGPNGAGKSTLLARMAGLL-PGQGEILLNGRPLSdWSAAELARHR--AYLSQQQSPPFAMPVFQYLA 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 102 LGLSTGISAAEIEREIRLLGEKYGLEVDPASVVMELSMGERQRVEILRALMT-------KPKLLILDEPTSVL--TPQAV 172
Cdd:COG4138    92 LHQPAGASSEAVEQLLAQLAEALGLEDKLSRPLTQLSGGEWQRVRLAAVLLQvwptinpEGQLLLLDEPMNSLdvAQQAA 171

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 173 rkLFKTLHQLSSEGVSILFISHKLDEIRELADRCVVLRAGKVVASVDPKAE-SEENLARL 231
Cdd:COG4138   172 --LDRLLRELCQQGITVVMSSHDLNHTLRHADRVWLLKQGKLVASGETAEVmTPENLSEV 229

cbiO

PRK13648

cobalt transporter ATP-binding subunit; Provisional

2-238

8.39e-24

cobalt transporter ATP-binding subunit; Provisional

Pssm-ID: 184207 [Multi-domain] Cd Length: 269 Bit Score: 100.60 E-value: 8.39e-24

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   2 TPRLSLRNITKRYPGITAN--DHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQAREl 79
Cdd:PRK13648    5 NSIIVFKNVSFQYQSDASFtlKDVSFNIPKGQWTSIVGHNGSGKSTIAKLMIGIEKVKSGEIFYNNQAITDDNFEKLRK- 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  80 GIAMVHQHFA-LFDTLSVTENVALGLST-GISAAEIEREIRLLGEKYGL----EVDPASvvmeLSMGERQRVEILRALMT 153
Cdd:PRK13648   84 HIGIVFQNPDnQFVGSIVKYDVAFGLENhAVPYDEMHRRVSEALKQVDMleraDYEPNA----LSGGQKQRVAIAGVLAL 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 154 KPKLLILDEPTSVLTPQAVRKLFKTLHQLSSE-GVSILFISHKLDEIRElADRCVVLRAGKVVASVDPKAESEENLARLM 232
Cdd:PRK13648  160 NPSVIILDEATSMLDPDARQNLLDLVRKVKSEhNITIISITHDLSEAME-ADHVIVMNKGTVYKEGTPTEIFDHAEELTR 238


                  ....*.
gi 2549828669 233 IGNDPP 238
Cdd:PRK13648  239 IGLDLP 244

cbiO

PRK13649

energy-coupling factor transporter ATPase;

23-221

1.06e-23

energy-coupling factor transporter ATPase;

Pssm-ID: 184208 [Multi-domain] Cd Length: 280 Bit Score: 100.59 E-value: 1.06e-23

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  23 VSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGhplgVETPAQARELGIAMVHQHFAL---------FDT 93
Cdd:PRK13649   26 VNLTIEDGSYTAFIGHTGSGKSTIMQLLNGLHVPTQGSVRVDD----TLITSTSKNKDIKQIRKKVGLvfqfpesqlFEE 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  94 lSVTENVALGLST-GISAAEIER----EIRLLGEKYGL-EVDPasvvMELSMGERQRVEILRALMTKPKLLILDEPTSVL 167
Cdd:PRK13649  102 -TVLKDVAFGPQNfGVSQEEAEAlareKLALVGISESLfEKNP----FELSGGQMRRVAIAGILAMEPKILVLDEPTAGL 176

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2549828669 168 TPQAVRKL---FKTLHQlssEGVSILFISHKLDEIRELADRCVVLRAGKVVASVDPK 221
Cdd:PRK13649  177 DPKGRKELmtlFKKLHQ---SGMTIVLVTHLMDDVANYADFVYVLEKGKLVLSGKPK 230

PRK10584

putative ABC transporter ATP-binding protein YbbA; Provisional

23-214

1.40e-23

putative ABC transporter ATP-binding protein YbbA; Provisional

Pssm-ID: 182569 [Multi-domain] Cd Length: 228 Bit Score: 99.08 E-value: 1.40e-23

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  23 VSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGV---ETPAQARELGIAMVHQHFALFDTLSVTEN 99
Cdd:PRK10584   29 VELVVKRGETIALIGESGSGKSTLLAILAGLDDGSSGEVSLVGQPLHQmdeEARAKLRAKHVGFVFQSFMLIPTLNALEN 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 100 VAL-GLSTGISAAEIEREIRLLGEKYGLEVDPASVVMELSMGERQRVEILRALMTKPKLLILDEPTSVLTPQAVRKLFKT 178
Cdd:PRK10584  109 VELpALLRGESSRQSRNGAKALLEQLGLGKRLDHLPAQLSGGEQQRVALARAFNGRPDVLFADEPTGNLDRQTGDKIADL 188

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 2549828669 179 LHQLSSE-GVSILFISHKlDEIRELADRCVVLRAGKV 214
Cdd:PRK10584  189 LFSLNREhGTTLILVTHD-LQLAARCDRRLRLVNGQL 224

3a01208

TIGR00958

Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]

24-215

2.55e-23

Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]

Pssm-ID: 273363 [Multi-domain] Cd Length: 711 Bit Score: 103.65 E-value: 2.55e-23

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  24 SLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLgVETPAQARELGIAMVHQHFALFDTlSVTENVALG 103
Cdd:TIGR00958 501 TFTLHPGEVVALVGPSGSGKSTVAALLQNLYQPTGGQVLLDGVPL-VQYDHHYLHRQVALVGQEPVLFSG-SVRENIAYG 578

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 104 LS--------TGISAAEIEREIRLLGEKYGLEVDPASVvmELSMGERQRVEILRALMTKPKLLILDEPTSVLTPQAVRkl 175
Cdd:TIGR00958 579 LTdtpdeeimAAAKAANAHDFIMEFPNGYDTEVGEKGS--QLSGGQKQRIAIARALVRKPRVLILDEATSALDAECEQ-- 654

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 2549828669 176 fkTLHQL-SSEGVSILFISHKLDEIRElADRCVVLRAGKVV 215
Cdd:TIGR00958 655 --LLQESrSRASRTVLLIAHRLSTVER-ADQILVLKKGSVV 692

PRK11176

lipid A ABC transporter ATP-binding protein/permease MsbA;

5-215

3.26e-23

lipid A ABC transporter ATP-binding protein/permease MsbA;

Pssm-ID: 183016 [Multi-domain] Cd Length: 582 Bit Score: 103.17 E-value: 3.26e-23

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   5 LSLRNITKRYPG--ITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQARElGIA 82
Cdd:PRK11176  342 IEFRNVTFTYPGkeVPALRNINFKIPAGKTVALVGRSGSGKSTIANLLTRFYDIDEGEILLDGHDLRDYTLASLRN-QVA 420

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  83 MVHQHFALF-DTlsVTENVALGLSTGISAAEIEREIRLL-------GEKYGLEvdpaSVVME----LSMGERQRVEILRA 150
Cdd:PRK11176  421 LVSQNVHLFnDT--IANNIAYARTEQYSREQIEEAARMAyamdfinKMDNGLD----TVIGEngvlLSGGQRQRIAIARA 494

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2549828669 151 LMTKPKLLILDEPTSVLTPQAVRKLFKTLHQLSSEGVSiLFISHKLDEIrELADRCVVLRAGKVV 215
Cdd:PRK11176  495 LLRDSPILILDEATSALDTESERAIQAALDELQKNRTS-LVIAHRLSTI-EKADEILVVEDGEIV 557

PRK15079

oligopeptide ABC transporter ATP-binding protein OppF; Provisional

19-215

3.61e-23

oligopeptide ABC transporter ATP-binding protein OppF; Provisional

Pssm-ID: 185037 [Multi-domain] Cd Length: 331 Bit Score: 100.17 E-value: 3.61e-23

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  19 ANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQAREL--GIAMVHQH--FALFDTL 94
Cdd:PRK15079   36 AVDGVTLRLYEGETLGVVGESGCGKSTFARAIIGLVKATDGEVAWLGKDLLGMKDDEWRAVrsDIQMIFQDplASLNPRM 115

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  95 SVTENVALGLST---GISAAEIEREIRLLGEKYGLEvdPASV---VMELSMGERQRVEILRALMTKPKLLILDEPTSVLT 168
Cdd:PRK15079  116 TIGEIIAEPLRTyhpKLSRQEVKDRVKAMMLKVGLL--PNLInryPHEFSGGQCQRIGIARALILEPKLIICDEPVSALD 193

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 2549828669 169 PQAVRKLFKTLHQLSSE-GVSILFISHKLDEIRELADRCVVLRAGKVV 215
Cdd:PRK15079  194 VSIQAQVVNLLQQLQREmGLSLIFIAHDLAVVKHISDRVLVMYLGHAV 241

PRK15134

microcin C ABC transporter ATP-binding protein YejF; Provisional

21-292

5.45e-23

microcin C ABC transporter ATP-binding protein YejF; Provisional

Pssm-ID: 237917 [Multi-domain] Cd Length: 529 Bit Score: 102.09 E-value: 5.45e-23

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  21 DHVSLDIAPGEVLAILGENGAGKS-TLMKIIYGAARPD----EGEISFDGHPLGVETPAQAREL---GIAMVHQH--FAL 90
Cdd:PRK15134   26 NDVSLQIEAGETLALVGESGSGKSvTALSILRLLPSPPvvypSGDIRFHGESLLHASEQTLRGVrgnKIAMIFQEpmVSL 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  91 FDTLSVTENVA--LGLSTGISAAEIEREIRLLGEKYGLEvDPASVVM----ELSMGERQRVEILRALMTKPKLLILDEPT 164
Cdd:PRK15134  106 NPLHTLEKQLYevLSLHRGMRREAARGEILNCLDRVGIR-QAAKRLTdyphQLSGGERQRVMIAMALLTRPELLIADEPT 184

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 165 SVL--TPQAvrKLFKTLHQLSSE-GVSILFISHKLDEIRELADRCVVLRAGKVVasvdpkaesEENLARLMIG------- 234
Cdd:PRK15134  185 TALdvSVQA--QILQLLRELQQElNMGLLFITHNLSIVRKLADRVAVMQNGRCV---------EQNRAATLFSapthpyt 253

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2549828669 235 ---------NDPPTVREGTAKAGEVvfEMRHVSAPGS----TRVCG----IDNVSLAVRAGEIVGIAGISGNGQA 292
Cdd:PRK15134  254 qkllnsepsGDPVPLPEPASPLLDV--EQLQVAFPIRkgilKRTVDhnvvVKNISFTLRPGETLGLVGESGSGKS 326

CydC

TIGR02868

thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ...

3-196

5.77e-23

thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.

Pssm-ID: 274331 [Multi-domain] Cd Length: 530 Bit Score: 102.05 E-value: 5.77e-23

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   3 PRLSLRNITKRYPG-ITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQARELgI 81
Cdd:TIGR02868 333 PTLELRDLSAGYPGaPPVLDGVSLDLPPGERVAILGPSGSGKSTLLATLAGLLDPLQGEVTLDGVPVSSLDQDEVRRR-V 411

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  82 AMVHQHFALFDTlSVTENVALG--------LSTGISAAEIEREIRLLGEkyGLEVDPASVVMELSMGERQRVEILRALMT 153
Cdd:TIGR02868 412 SVCAQDAHLFDT-TVRENLRLArpdatdeeLWAALERVGLADWLRALPD--GLDTVLGEGGARLSGGERQRLALARALLA 488

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 2549828669 154 KPKLLILDEPTSVLTPQAVRKLFKTLHQlSSEGVSILFISHKL 196
Cdd:TIGR02868 489 DAPILLLDEPTEHLDAETADELLEDLLA-ALSGRTVVLITHHL 530

ABCF_EF-3

cd03221

ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ...

5-213

6.28e-23

ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.

Pssm-ID: 213188 [Multi-domain] Cd Length: 144 Bit Score: 94.44 E-value: 6.28e-23

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   5 LSLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHplgvetpaqareLGIAMV 84
Cdd:cd03221     1 IELENLSKTYGGKLLLKDISLTINPGDRIGLVGRNGAGKSTLLKLIAGELEPDEGIVTWGST------------VKIGYF 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  85 HQhfalfdtlsvtenvalglstgisaaeiereirllgekyglevdpasvvmeLSMGERQRVEILRALMTKPKLLILDEPT 164
Cdd:cd03221    69 EQ--------------------------------------------------LSGGEKMRLALAKLLLENPNLLLLDEPT 98

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 2549828669 165 SVLTPQAVRKLFKTLHQLSSegvSILFISHKLDEIRELADRCVVLRAGK 213
Cdd:cd03221    99 NHLDLESIEALEEALKEYPG---TVILVSHDRYFLDQVATKIIELEDGK 144

PRK10535

macrolide ABC transporter ATP-binding protein/permease MacB;

1-242

6.48e-23

macrolide ABC transporter ATP-binding protein/permease MacB;

Pssm-ID: 182528 [Multi-domain] Cd Length: 648 Bit Score: 102.49 E-value: 6.48e-23

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   1 MTPRLSLRNITKRYPG----ITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGH---PLGVETP 73
Cdd:PRK10535    1 MTALLELKDIRRSYPSgeeqVEVLKGISLDIYAGEMVAIVGASGSGKSTLMNILGCLDKPTSGTYRVAGQdvaTLDADAL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  74 AQARELGIAMVHQHFALFDTLSVTENVAL-GLSTGISAAE-IEREIRLLGeKYGLEVDPASVVMELSMGERQRVEILRAL 151
Cdd:PRK10535   81 AQLRREHFGFIFQRYHLLSHLTAAQNVEVpAVYAGLERKQrLLRAQELLQ-RLGLEDRVEYQPSQLSGGQQQRVSIARAL 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 152 MTKPKLLILDEPTSVLTPQAVRKLFKTLHQLSSEGVSILFISHKlDEIRELADRCVVLRAGKVVASVDPKAESEENLARL 231
Cdd:PRK10535  160 MNGGQVILADEPTGALDSHSGEEVMAILHQLRDRGHTVIIVTHD-PQVAAQAERVIEIRDGEIVRNPPAQEKVNVAGGTE 238

                         250
                  ....*....|.
gi 2549828669 232 MIGNDPPTVRE 242
Cdd:PRK10535  239 PVVNTASGWRQ 249

ABC2_perm_RbbA

ribosome-associated ATPase/putative transporter RbbA;

8-222

6.65e-23

ribosome-associated ATPase/putative transporter RbbA;

Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 102.90 E-value: 6.65e-23

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   8 RNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGvetpaqARELGIAM---- 83
Cdd:NF033858  270 RGLTMRFGDFTAVDHVSFRIRRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGEAWLFGQPVD------AGDIATRRrvgy 343

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  84 VHQHFALFDTLSVTENVALG--LsTGISAAEIEREIRLLGEKYGLE--VD--PASvvmeLSMGERQRVEILRALMTKPKL 157
Cdd:NF033858  344 MSQAFSLYGELTVRQNLELHarL-FHLPAAEIAARVAEMLERFDLAdvADalPDS----LPLGIRQRLSLAVAVIHKPEL 418

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2549828669 158 LILDEPTSVLTPQAvRKLF-KTLHQLSSE-GVSIlFIS-HKLDEIrELADRCVVLRAGKVVASVDPKA 222
Cdd:NF033858  419 LILDEPTSGVDPVA-RDMFwRLLIELSREdGVTI-FIStHFMNEA-ERCDRISLMHAGRVLASDTPAA 483

CcmA

COG1131

ABC-type multidrug transport system, ATPase component [Defense mechanisms];

268-471

7.82e-23

ABC-type multidrug transport system, ATPase component [Defense mechanisms];

Pssm-ID: 440746 [Multi-domain] Cd Length: 236 Bit Score: 97.06 E-value: 7.82e-23

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 268 IDNVSLAVRAGEIVGIAGISGNGQ-------ARFMAAASGEylceadrVLLFNSPVGELDTHARRISGlrYVPEQrlgHA 340
Cdd:COG1131    16 LDGVSLTVEPGEIFGLLGPNGAGKtttirmlLGLLRPTSGE-------VRVLGEDVARDPAEVRRRIG--YVPQE---PA 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 341 AVPELSLTANTYLTGDSLVRSGFILRDRARSfanlVIERFHVkTPNAEKAAGSLSGGNLQKFIMGREILNRPRVLLVHQP 420
Cdd:COG1131    84 LYPDLTVRENLRFFARLYGLPRKEARERIDE----LLELFGL-TDAADRKVGTLSGGMKQRLGLALALLHDPELLILDEP 158

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2549828669 421 TWGVDVGAAAVIRNSLIRLRDDGAAIIVVSEEIDELFEISDRIAVMYRGAL 471
Cdd:COG1131   159 TSGLDPEARRELWELLRELAAEGKTVLLSTHYLEEAERLCDRVAIIDKGRI 209

PstB

COG1117

ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; ...

1-215

9.76e-23

ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism];

Pssm-ID: 440734 [Multi-domain] Cd Length: 258 Bit Score: 97.41 E-value: 9.76e-23

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   1 MTPRLSLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKII------YGAARPdEGEISFDGHPL---GVE 71
Cdd:COG1117     8 LEPKIEVRNLNVYYGDKQALKDINLDIPENKVTALIGPSGCGKSTLLRCLnrmndlIPGARV-EGEILLDGEDIydpDVD 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  72 TPAQARELGiaMVHQH---FALfdtlSVTENVALGLST-GI-SAAEIErEI--RLLgEKYGL--EV-----DPAsvvMEL 137
Cdd:COG1117    87 VVELRRRVG--MVFQKpnpFPK----SIYDNVAYGLRLhGIkSKSELD-EIveESL-RKAALwdEVkdrlkKSA---LGL 155

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2549828669 138 SMGERQRVEILRALMTKPKLLILDEPTSVLTPQAVRKLFKTLHQLSSEgVSILFISHKLDEIRELADRCVVLRAGKVV 215
Cdd:COG1117   156 SGGQQQRLCIARALAVEPEVLLMDEPTSALDPISTAKIEELILELKKD-YTIVIVTHNMQQAARVSDYTAFFYLGELV 232

cbiO

PRK13640

energy-coupling factor transporter ATPase;

5-220

1.02e-22

energy-coupling factor transporter ATPase;

Pssm-ID: 184200 [Multi-domain] Cd Length: 282 Bit Score: 97.95 E-value: 1.02e-22

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   5 LSLRNITKRYPG--ITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGE---ISFDGHPLGVETPAQARE- 78
Cdd:PRK13640    6 VEFKHVSFTYPDskKPALNDISFSIPRGSWTALIGHNGSGKSTISKLINGLLLPDDNPnskITVDGITLTAKTVWDIREk 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  79 LGIamVHQH-FALFDTLSVTENVALGLST-GISAAEIEREIRLLGEKYGL----EVDPASvvmeLSMGERQRVEILRALM 152
Cdd:PRK13640   86 VGI--VFQNpDNQFVGATVGDDVAFGLENrAVPRPEMIKIVRDVLADVGMldyiDSEPAN----LSGGQKQRVAIAGILA 159

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2549828669 153 TKPKLLILDEPTSVLTPQAVRKLFKTLHQLSSE-GVSILFISHKLDEIrELADRCVVLRAGKVVASVDP 220
Cdd:PRK13640  160 VEPKIIILDESTSMLDPAGKEQILKLIRKLKKKnNLTVISITHDIDEA-NMADQVLVLDDGKLLAQGSP 227

CeuD

COG4604

ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and ...

6-231

1.02e-22

ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism];

Pssm-ID: 443654 [Multi-domain] Cd Length: 252 Bit Score: 97.08 E-value: 1.02e-22

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   6 SLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGvETPAQ--ARELGIAM 83
Cdd:COG4604     3 EIKNVSKRYGGKVVLDDVSLTIPKGGITALIGPNGAGKSTLLSMISRLLPPDSGEVLVDGLDVA-TTPSRelAKRLAILR 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  84 VHQHFALfdTLSVTENVALG--------LsTGISAAEIEREIRLLG-----EKYgleVDpasvvmELSMGERQRVEILRA 150
Cdd:COG4604    82 QENHINS--RLTVRELVAFGrfpyskgrL-TAEDREIIDEAIAYLDledlaDRY---LD------ELSGGQRQRAFIAMV 149

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 151 LMTKPKLLILDEPTSVLTPQAVRKLFKTLHQLSSE-GVSILFISHKLDEIRELADRCVVLRAGKVVASvDPKAE--SEEN 227
Cdd:COG4604   150 LAQDTDYVLLDEPLNNLDMKHSVQMMKLLRRLADElGKTVVIVLHDINFASCYADHIVAMKDGRVVAQ-GTPEEiiTPEV 228


                  ....
gi 2549828669 228 LARL 231
Cdd:COG4604   229 LSDI 232

cbiO

PRK13652

cobalt transporter ATP-binding subunit; Provisional

5-217

1.17e-22

cobalt transporter ATP-binding subunit; Provisional

Pssm-ID: 172200 [Multi-domain] Cd Length: 277 Bit Score: 97.57 E-value: 1.17e-22

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   5 LSLRNITKRYPG-ITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQARE-LGIA 82
Cdd:PRK13652    4 IETRDLCYSYSGsKEALNNINFIAPRNSRIAVIGPNGAGKSTLFRHFNGILKPTSGSVLIRGEPITKENIREVRKfVGLV 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  83 MVHQHFALFDTlSVTENVA-----LGLSTGISAAEIEREIRLLGekygLEVDPASVVMELSMGERQRVEILRALMTKPKL 157
Cdd:PRK13652   84 FQNPDDQIFSP-TVEQDIAfgpinLGLDEETVAHRVSSALHMLG----LEELRDRVPHHLSGGEKKRVAIAGVIAMEPQV 158

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2549828669 158 LILDEPTSVLTPQAVRKLFKTLHQLSSE-GVSILFISHKLDEIRELADRCVVLRAGKVVAS 217
Cdd:PRK13652  159 LVLDEPTAGLDPQGVKELIDFLNDLPETyGMTVIFSTHQLDLVPEMADYIYVMDKGRIVAY 219

PRK13651

cobalt transporter ATP-binding subunit; Provisional

7-220

1.20e-22

cobalt transporter ATP-binding subunit; Provisional

Pssm-ID: 184210 [Multi-domain] Cd Length: 305 Bit Score: 98.23 E-value: 1.20e-22

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   7 LRNITKRYPG-----ITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISF---DGHPLGVETPAQA-- 76
Cdd:PRK13651    5 VKNIVKIFNKklpteLKALDNVSVEINQGEFIAIIGQTGSGKTTFIEHLNALLLPDTGTIEWifkDEKNKKKTKEKEKvl 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  77 --------------------RELGIAMVHQHFALFDTlSVTENVALG-LSTGISAAEIERE----IRLLG--EKYgLEVD 129
Cdd:PRK13651   85 eklviqktrfkkikkikeirRRVGVVFQFAEYQLFEQ-TIEKDIIFGpVSMGVSKEEAKKRaakyIELVGldESY-LQRS 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 130 PasvvMELSMGERQRVEILRALMTKPKLLILDEPTSVLTPQAVRKLFKTLHQLSSEGVSILFISHKLDEIRELADRCVVL 209
Cdd:PRK13651  163 P----FELSGGQKRRVALAGILAMEPDFLVFDEPTAGLDPQGVKEILEIFDNLNKQGKTIILVTHDLDNVLEWTKRTIFF 238

                         250
                  ....*....|.
gi 2549828669 210 RAGKVVASVDP 220
Cdd:PRK13651  239 KDGKIIKDGDT 249

cbiO

PRK13641

energy-coupling factor transporter ATPase;

21-222

1.31e-22

energy-coupling factor transporter ATPase;

Pssm-ID: 237456 [Multi-domain] Cd Length: 287 Bit Score: 97.59 E-value: 1.31e-22

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  21 DHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQA-----RELGIAMVHQHFALFDTlS 95
Cdd:PRK13641   24 DNISFELEEGSFVALVGHTGSGKSTLMQHFNALLKPSSGTITIAGYHITPETGNKNlkklrKKVSLVFQFPEAQLFEN-T 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  96 VTENVALG-LSTGISAAEIEREIRLLGEKYGLEVDPAS-VVMELSMGERQRVEILRALMTKPKLLILDEPTSVLTPQAVR 173
Cdd:PRK13641  103 VLKDVEFGpKNFGFSEDEAKEKALKWLKKVGLSEDLISkSPFELSGGQMRRVAIAGVMAYEPEILCLDEPAAGLDPEGRK 182

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 2549828669 174 KLFKTLHQLSSEGVSILFISHKLDEIRELADRCVVLRAGKVVASVDPKA 222
Cdd:PRK13641  183 EMMQLFKDYQKAGHTVILVTHNMDDVAEYADDVLVLEHGKLIKHASPKE 231

ssuB

PRK11247

aliphatic sulfonates transport ATP-binding subunit; Provisional

2-214

2.11e-22

aliphatic sulfonates transport ATP-binding subunit; Provisional

Pssm-ID: 183055 [Multi-domain] Cd Length: 257 Bit Score: 96.29 E-value: 2.11e-22

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   2 TPrLSLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLgvetpAQARElGI 81
Cdd:PRK11247   11 TP-LLLNAVSKRYGERTVLNQLDLHIPAGQFVAVVGRSGCGKSTLLRLLAGLETPSAGELLAGTAPL-----AEARE-DT 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  82 AMVHQHFALFDTLSVTENVALGLSTGISAAEIEREirllgEKYGLEVDPASVVMELSMGERQRVEILRALMTKPKLLILD 161
Cdd:PRK11247   84 RLMFQDARLLPWKKVIDNVGLGLKGQWRDAALQAL-----AAVGLADRANEWPAALSGGQKQRVALARALIHRPGLLLLD 158

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2549828669 162 EP---TSVLTPQAVRKLFKTLHQlsSEGVSILFISHKLDEIRELADRCVVLRAGKV 214
Cdd:PRK11247  159 EPlgaLDALTRIEMQDLIESLWQ--QHGFTVLLVTHDVSEAVAMADRVLLIEEGKI 212

PRK11831

phospholipid ABC transporter ATP-binding protein MlaF;

21-242

2.60e-22

phospholipid ABC transporter ATP-binding protein MlaF;

Pssm-ID: 236997 [Multi-domain] Cd Length: 269 Bit Score: 96.37 E-value: 2.60e-22

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  21 DHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLgvetPAQAREL------GIAMVHQHFALFDTL 94
Cdd:PRK11831   24 DNISLTVPRGKITAIMGPSGIGKTTLLRLIGGQIAPDHGEILFDGENI----PAMSRSRlytvrkRMSMLFQSGALFTDM 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  95 SVTENVALGLS--TGISAAEIEREIRLLGEKYGLEVDPASVVMELSMGERQRVEILRALMTKPKLLILDEPTSVLTPQAV 172
Cdd:PRK11831  100 NVFDNVAYPLRehTQLPAPLLHSTVMMKLEAVGLRGAAKLMPSELSGGMARRAALARAIALEPDLIMFDEPFVGQDPITM 179

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2549828669 173 RKLFKTLHQLSSE-GVSILFISHKLDEIRELADRCVVLRAGKVVASVDPKAESEenlarlmigNDPPTVRE 242
Cdd:PRK11831  180 GVLVKLISELNSAlGVTCVVVSHDVPEVLSIADHAYIVADKKIVAHGSAQALQA---------NPDPRVRQ 241

cbiO

PRK13638

energy-coupling factor ABC transporter ATP-binding protein;

23-220

2.64e-22

energy-coupling factor ABC transporter ATP-binding protein;

Pssm-ID: 184198 [Multi-domain] Cd Length: 271 Bit Score: 96.61 E-value: 2.64e-22

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  23 VSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVEtpaqarELGIAMVHQHFA---------LFDT 93
Cdd:PRK13638   20 LNLDFSLSPVTGLVGANGCGKSTLFMNLSGLLRPQKGAVLWQGKPLDYS------KRGLLALRQQVAtvfqdpeqqIFYT 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  94 lSVTENVALGL-STGISAAEIEREIR---LLGEKYGLEVDPasvVMELSMGERQRVEILRALMTKPKLLILDEPTSVLTP 169
Cdd:PRK13638   94 -DIDSDIAFSLrNLGVPEAEITRRVDealTLVDAQHFRHQP---IQCLSHGQKKRVAIAGALVLQARYLLLDEPTAGLDP 169

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2549828669 170 QAVRKLFKTLHQLSSEGVSILFISHKLDEIRELADRCVVLRAGKVVASVDP 220
Cdd:PRK13638  170 AGRTQMIAIIRRIVAQGNHVIISSHDIDLIYEISDAVYVLRQGQILTHGAP 220

cbiO

PRK13644

energy-coupling factor transporter ATPase;

5-262

4.16e-22

energy-coupling factor transporter ATPase;

Pssm-ID: 106587 [Multi-domain] Cd Length: 274 Bit Score: 95.82 E-value: 4.16e-22

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   5 LSLRNITKRYP-GITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQARELGIAM 83
Cdd:PRK13644    2 IRLENVSYSYPdGTPALENINLVIKKGEYIGIIGKNGSGKSTLALHLNGLLRPQKGKVLVSGIDTGDFSKLQGIRKLVGI 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  84 VHQH-FALFDTLSVTENVALGLST-GISAAEIEREIRLLGEKYGLEVDPASVVMELSMGERQRVEILRALMTKPKLLILD 161
Cdd:PRK13644   82 VFQNpETQFVGRTVEEDLAFGPENlCLPPIEIRKRVDRALAEIGLEKYRHRSPKTLSGGQGQCVALAGILTMEPECLIFD 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 162 EPTSVLTPQAVRKLFKTLHQLSSEGVSILFISHKLDEIRElADRCVVLRAGKVVASVDPKAE-SEENLARLmiGNDPPTV 240
Cdd:PRK13644  162 EVTSMLDPDSGIAVLERIKKLHEKGKTIVYITHNLEELHD-ADRIIVMDRGKIVLEGEPENVlSDVSLQTL--GLTPPSL 238

                         250       260
                  ....*....|....*....|....
gi 2549828669 241 RE--GTAKAGEVVFEMRHVSAPGS 262
Cdd:PRK13644  239 IElaENLKMHGVVIPWENTSSPSS 262

fecE

PRK11231

Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;

5-237

5.61e-22

Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;

Pssm-ID: 183044 [Multi-domain] Cd Length: 255 Bit Score: 95.08 E-value: 5.61e-22

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   5 LSLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQ-ARELgiAM 83
Cdd:PRK11231    3 LRTENLTVGYGTKRILNDLSLSLPTGKITALIGPNGCGKSTLLKCFARLLTPQSGTVFLGDKPISMLSSRQlARRL--AL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  84 VHQHFALFDTLSVTENVALGLSTGIS-----AAEIEREIRLLGEKYGLEVDPASVVMELSMGERQRVEILRALMTKPKLL 158
Cdd:PRK11231   81 LPQHHLTPEGITVRELVAYGRSPWLSlwgrlSAEDNARVNQAMEQTRINHLADRRLTDLSGGQRQRAFLAMVLAQDTPVV 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 159 ILDEPTSVLTPQAVRKLFKTLHQLSSEGVSILFISHKLDEIRELADRCVVLRAGKVVASVDPKAESEENLAR------LM 232
Cdd:PRK11231  161 LLDEPTTYLDINHQVELMRLMRELNTQGKTVVTVLHDLNQASRYCDHLVVLANGHVMAQGTPEEVMTPGLLRtvfdveAE 240


                  ....*
gi 2549828669 233 IGNDP 237
Cdd:PRK11231  241 IHPEP 245

PRK11160

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed

5-217

6.16e-22

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed

Pssm-ID: 236865 [Multi-domain] Cd Length: 574 Bit Score: 99.13 E-value: 6.16e-22

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   5 LSLRNITKRYPGITAN--DHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQARElGIA 82
Cdd:PRK11160  339 LTLNNVSFTYPDQPQPvlKGLSLQIKAGEKVALLGRTGCGKSTLLQLLTRAWDPQQGEILLNGQPIADYSEAALRQ-AIS 417

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  83 MVHQHFALF-DTLSvtENVALGLSTgisaAEIEREIRLLgEKYGLEV---DPASVVM-------ELSMGERQRVEILRAL 151
Cdd:PRK11160  418 VVSQRVHLFsATLR--DNLLLAAPN----ASDEALIEVL-QQVGLEKlleDDKGLNAwlgeggrQLSGGEQRRLGIARAL 490

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2549828669 152 MTKPKLLILDEPTSVLTPQAVRKLFKTLHQLsSEGVSILFISHKLDEIrELADRCVVLRAGKVVAS 217
Cdd:PRK11160  491 LHDAPLLLLDEPTEGLDAETERQILELLAEH-AQNKTVLMITHRLTGL-EQFDRICVMDNGQIIEQ 554

PRK09984

phosphonate ABC transporter ATP-binding protein;

1-214

9.31e-22

phosphonate ABC transporter ATP-binding protein;

Pssm-ID: 182182 [Multi-domain] Cd Length: 262 Bit Score: 94.69 E-value: 9.31e-22

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   1 MTPRLSLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPD---EGEISFDGHPLGVETPAqAR 77
Cdd:PRK09984    1 MQTIIRVEKLAKTFNQHQALHAVDLNIHHGEMVALLGPSGSGKSTLLRHLSGLITGDksaGSHIELLGRTVQREGRL-AR 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  78 ELGIAMVH-----QHFALFDTLSVTENVALGL--STGI--------SAAEIEREIRLLgEKYGLEVDPASVVMELSMGER 142
Cdd:PRK09984   80 DIRKSRANtgyifQQFNLVNRLSVLENVLIGAlgSTPFwrtcfswfTREQKQRALQAL-TRVGMVHFAHQRVSTLSGGQQ 158

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2549828669 143 QRVEILRALMTKPKLLILDEPTSVLTPQAVRKLFKTLHQLS-SEGVSILFISHKLDEIRELADRCVVLRAGKV 214
Cdd:PRK09984  159 QRVAIARALMQQAKVILADEPIASLDPESARIVMDTLRDINqNDGITVVVTLHQVDYALRYCERIVALRQGHV 231

PRK14239

phosphate transporter ATP-binding protein; Provisional

1-215

1.00e-21

phosphate transporter ATP-binding protein; Provisional

Pssm-ID: 184585 [Multi-domain] Cd Length: 252 Bit Score: 94.46 E-value: 1.00e-21

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   1 MTPRLSLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKII--YGAARPD---EGEISFDGHPL---GVET 72
Cdd:PRK14239    2 TEPILQVSDLSVYYNKKKALNSVSLDFYPNEITALIGPSGSGKSTLLRSInrMNDLNPEvtiTGSIVYNGHNIyspRTDT 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  73 PAQARELGiaMVHQHFALFdTLSVTENVALGLS-TGISAAEIEREI---RLLGEKYGLEV-----DPAsvvMELSMGERQ 143
Cdd:PRK14239   82 VDLRKEIG--MVFQQPNPF-PMSIYENVVYGLRlKGIKDKQVLDEAvekSLKGASIWDEVkdrlhDSA---LGLSGGQQQ 155

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2549828669 144 RVEILRALMTKPKLLILDEPTSVLTPQAVRKLFKTLHQLSSEgVSILFISHKLDEIRELADRCVVLRAGKVV 215
Cdd:PRK14239  156 RVCIARVLATSPKIILLDEPTSALDPISAGKIEETLLGLKDD-YTMLLVTRSMQQASRISDRTGFFLDGDLI 226

anch_rpt_ABC

TIGR03771

anchored repeat-type ABC transporter, ATP-binding subunit; This protein family is the ...

25-220

2.19e-21

anchored repeat-type ABC transporter, ATP-binding subunit; This protein family is the ATP-binding cassette subunit of binding protein-dependent ABC transporter complex that strictly co-occurs with TIGR03769. TIGRFAMs model TIGR03769 describes a protein domain that occurs singly or as one of up to three repeats in proteins of a number of Actinobacteria, including Propionibacterium acnes KPA171202. The TIGR03769 domain occurs both in an adjacent gene for the substrate-binding protein and in additional (often nearby) proteins, often with LPXTG-like sortase recognition signals. Homologous ATP-binding subunits outside the scope of this family include manganese transporter MntA in Synechocystis sp. PCC 6803 and chelated iron transporter subunits. The function of this transporter complex is unknown. [Transport and binding proteins, Unknown substrate]

Pssm-ID: 163483 [Multi-domain] Cd Length: 223 Bit Score: 92.61 E-value: 2.19e-21

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  25 LDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGvetpAQARELGIAMVHQHFALFDTLSVTENVALGL 104
Cdd:TIGR03771   1 LSADKGELLGLLGPNGAGKTTLLRAILGLIPPAKGTVKVAGASPG----KGWRHIGYVPQRHEFAWDFPISVAHTVMSGR 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 105 STGI-----SAAEIEREIRLLGEKYGLEVDPASVVMELSMGERQRVEILRALMTKPKLLILDEPTSVLTPQAVRKLFKTL 179
Cdd:TIGR03771  77 TGHIgwlrrPCVADFAAVRDALRRVGLTELADRPVGELSGGQRQRVLVARALATRPSVLLLDEPFTGLDMPTQELLTELF 156

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 2549828669 180 HQLSSEGVSILFISHKLDEIRELADRcVVLRAGKVVASVDP 220
Cdd:TIGR03771 157 IELAGAGTAILMTTHDLAQAMATCDR-VVLLNGRVIADGTP 196

ABCC_MRP_domain2

cd03244

ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C ...

3-220

3.44e-21

ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resistance lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.

Pssm-ID: 213211 [Multi-domain] Cd Length: 221 Bit Score: 91.79 E-value: 3.44e-21

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   3 PRLSLRNITKRYP--GITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQARELg 80
Cdd:cd03244     1 GDIEFKNVSLRYRpnLPPVLKNISFSIKPGEKVGIVGRTGSGKSSLLLALFRLVELSSGSILIDGVDISKIGLHDLRSR- 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  81 IAMVHQHFALFDTlSVTENVA-LGLStgiSAAEIEREIRLLGEK-------YGLEvdpaSVVME----LSMGERQRVEIL 148
Cdd:cd03244    80 ISIIPQDPVLFSG-TIRSNLDpFGEY---SDEELWQALERVGLKefveslpGGLD----TVVEEggenLSVGQRQLLCLA 151

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2549828669 149 RALMTKPKLLILDEPTSVLTPQAVRKLFKTLHQLSSeGVSILFISHKLDEIRElADRCVVLRAGKVVASVDP 220
Cdd:cd03244   152 RALLRKSKILVLDEATASVDPETDALIQKTIREAFK-DCTVLTIAHRLDTIID-SDRILVLDKGRVVEFDSP 221

PRK13657

glucan ABC transporter ATP-binding protein/ permease;

8-217

4.26e-21

glucan ABC transporter ATP-binding protein/ permease;

Pssm-ID: 184214 [Multi-domain] Cd Length: 588 Bit Score: 96.57 E-value: 4.26e-21

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   8 RNITKRYPGIT-ANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQARElGIAMVHQ 86
Cdd:PRK13657  338 DDVSFSYDNSRqGVEDVSFEAKPGQTVAIVGPTGAGKSTLINLLQRVFDPQSGRILIDGTDIRTVTRASLRR-NIAVVFQ 416

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  87 HFALFDTlSVTENVALGlSTGISAAEIEREIR-------LLGEKYGLEvdpaSVVME----LSMGERQRVEILRALMTKP 155
Cdd:PRK13657  417 DAGLFNR-SIEDNIRVG-RPDATDEEMRAAAEraqahdfIERKPDGYD----TVVGErgrqLSGGERQRLAIARALLKDP 490

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2549828669 156 KLLILDEPTSVLTPQAVRKLFKTLHQLsSEGVSILFISHKLDEIRElADRCVVLRAGKVVAS 217
Cdd:PRK13657  491 PILILDEATSALDVETEAKVKAALDEL-MKGRTTFIIAHRLSTVRN-ADRILVFDNGRVVES 550

PRK10575

Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;

6-220

5.15e-21

Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;

Pssm-ID: 182561 [Multi-domain] Cd Length: 265 Bit Score: 92.54 E-value: 5.15e-21

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   6 SLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGV-ETPAQARElgIAMV 84
Cdd:PRK10575   13 ALRNVSFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESwSSKAFARK--VAYL 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  85 HQHFALFDTLSVTENVALGL-----STGISAAE----IEREIRLLGEKyglevdPAS--VVMELSMGERQRVEILRALMT 153
Cdd:PRK10575   91 PQQLPAAEGMTVRELVAIGRypwhgALGRFGAAdrekVEEAISLVGLK------PLAhrLVDSLSGGERQRAWIAMLVAQ 164

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2549828669 154 KPKLLILDEPTSVLTPQAVRKLFKTLHQLSSE-GVSILFISHKLDEIRELADRCVVLRAGKVVASVDP 220
Cdd:PRK10575  165 DSRCLLLDEPTSALDIAHQVDVLALVHRLSQErGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTP 232

ccmA

TIGR01189

heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein ...

5-202

8.65e-21

heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein encoded by ccmA in bacteria. An exception is, an arabidopsis protein. Quite likely this is encoded by an organelle. Bacterial c-type cytocromes are located on the periplasmic side of the cytoplasmic membrane. Several gene products encoded in a locus designated as 'ccm' are implicated in the transport and assembly of the functional cytochrome C. This cluster includes genes: ccmA;B;C;D;E;F;G and H. The posttranslational pathway includes the transport of heme moiety, the secretion of the apoprotein and the covalent attachment of the heme with the apoprotein. The proteins ccmA and B represent an ABC transporter; ccmC and D participate in heme transfer to ccmE, which function as a periplasmic heme chaperone. The presence of ccmF, G and H is suggested to be obligatory for the final functional assembly of cytochrome c. [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Other]

Pssm-ID: 273491 [Multi-domain] Cd Length: 198 Bit Score: 90.11 E-value: 8.65e-21

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   5 LSLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQARElgIAMV 84
Cdd:TIGR01189   1 LAARNLACSRGERMLFEGLSFTLNAGEALQVTGPNGIGKTTLLRILAGLLRPDSGEVRWNGTPLAEQRDEPHEN--ILYL 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  85 HQHFALFDTLSVTENvaLGLSTGISAAEiEREIRLLGEKYGLEVDPASVVMELSMGERQRVEILRALMTKPKLLILDEPT 164
Cdd:TIGR01189  79 GHLPGLKPELSALEN--LHFWAAIHGGA-QRTIEDALAAVGLTGFEDLPAAQLSAGQQRRLALARLWLSRRPLWILDEPT 155

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 2549828669 165 SVLTPQAVRKLFKTLHQLSSEGVSILFISHK---LDEIREL 202
Cdd:TIGR01189 156 TALDKAGVALLAGLLRAHLARGGIVLLTTHQdlgLVEAREL 196

PRK15112

peptide ABC transporter ATP-binding protein SapF;

5-215

1.03e-20

peptide ABC transporter ATP-binding protein SapF;

Pssm-ID: 185067 [Multi-domain] Cd Length: 267 Bit Score: 91.77 E-value: 1.03e-20

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   5 LSLRNITK---------RYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQ 75
Cdd:PRK15112    5 LEVRNLSKtfryrtgwfRRQTVEAVKPLSFTLREGQTLAIIGENGSGKSTLAKMLAGMIEPTSGELLIDDHPLHFGDYSY 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  76 aRELGIAMVHQHFALF----DTLSVTENVALGLSTGISAAEIEREIRLLGEKYGLEVDPASVVME-LSMGERQRVEILRA 150
Cdd:PRK15112   85 -RSQRIRMIFQDPSTSlnprQRISQILDFPLRLNTDLEPEQREKQIIETLRQVGLLPDHASYYPHmLAPGQKQRLGLARA 163

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2549828669 151 LMTKPKLLILDEPTSVLTPQAVRKLFKTLHQLSSE-GVSILFISHKLDEIRELADRCVVLRAGKVV 215
Cdd:PRK15112  164 LILRPKVIIADEALASLDMSMRSQLINLMLELQEKqGISYIYVTQHLGMMKHISDQVLVMHQGEVV 229

PRK03695

vitamin B12-transporter ATPase; Provisional

23-230

1.38e-20

vitamin B12-transporter ATPase; Provisional

Pssm-ID: 235150 [Multi-domain] Cd Length: 248 Bit Score: 90.76 E-value: 1.38e-20

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  23 VSLDIAPGEVLAILGENGAGKSTLMKIIYGAArPDEGEISFDGHPLG-VETPAQARELGIaMVHQHFALFdTLSVTENVA 101
Cdd:PRK03695   15 LSAEVRAGEILHLVGPNGAGKSTLLARMAGLL-PGSGSIQFAGQPLEaWSAAELARHRAY-LSQQQTPPF-AMPVFQYLT 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 102 LGLSTGISAAEIEREIRLLGEKYGLEVDPASVVMELSMGERQRV-------EILRALMTKPKLLILDEPTSVL--TPQAV 172
Cdd:PRK03695   92 LHQPDKTRTEAVASALNEVAEALGLDDKLGRSVNQLSGGEWQRVrlaavvlQVWPDINPAGQLLLLDEPMNSLdvAQQAA 171

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2549828669 173 rkLFKTLHQLSSEGVSILFISHKLDEIRELADRCVVLRAGKVVASVDPK-AESEENLAR 230
Cdd:PRK03695  172 --LDRLLSELCQQGIAVVMSSHDLNHTLRHADRVWLLKQGKLLASGRRDeVLTPENLAQ 228

SapD

COG4170

ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];

3-217

2.96e-20

ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];

Pssm-ID: 443330 [Multi-domain] Cd Length: 331 Bit Score: 91.51 E-value: 2.96e-20

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   3 PRLSLRNITKRYPG----ITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPD----EGEISFDGHPLGVETPA 74
Cdd:COG4170     2 PLLDIRNLTIEIDTpqgrVKAVDRVSLTLNEGEIRGLVGESGSGKSLIAKAICGITKDNwhvtADRFRWNGIDLLKLSPR 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  75 QAREL---GIAMVHQHFAlfDTLSVTENVALGLSTGISAAE------------IEREIRLLgEKYGLEvDPaSVVM---- 135
Cdd:COG4170    82 ERRKIigrEIAMIFQEPS--SCLDPSAKIGDQLIEAIPSWTfkgkwwqrfkwrKKRAIELL-HRVGIK-DH-KDIMnsyp 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 136 -ELSMGERQRVEILRALMTKPKLLILDEPTSVL--TPQA-VRKLFKTLHQLSseGVSILFISHKLDEIRELADRCVVLRA 211
Cdd:COG4170   157 hELTEGECQKVMIAMAIANQPRLLIADEPTNAMesTTQAqIFRLLARLNQLQ--GTSILLISHDLESISQWADTITVLYC 234


                  ....*.
gi 2549828669 212 GKVVAS 217
Cdd:COG4170   235 GQTVES 240

ABCG_White

cd03234

White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ...

23-215

3.90e-20

White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.

Pssm-ID: 213201 [Multi-domain] Cd Length: 226 Bit Score: 89.25 E-value: 3.90e-20

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  23 VSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDE---GEISFDGHPLgveTPAQARELgIAMVHQHFALFDTLSVTE- 98
Cdd:cd03234    26 VSLHVESGQVMAILGSSGSGKTTLLDAISGRVEGGGttsGQILFNGQPR---KPDQFQKC-VAYVRQDDILLPGLTVREt 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  99 -----NVALGLSTGISAAEIEREIRLLGEkYGLEVDPASVVMELSMGERQRVEILRALMTKPKLLILDEPTSVLTPQAVR 173
Cdd:cd03234   102 ltytaILRLPRKSSDAIRKKRVEDVLLRD-LALTRIGGNLVKGISGGERRRVSIAVQLLWDPKVLILDEPTSGLDSFTAL 180

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 2549828669 174 KLFKTLHQLSSEGVSILFISHK-LDEIRELADRCVVLRAGKVV 215
Cdd:cd03234   181 NLVSTLSQLARRNRIVILTIHQpRSDLFRLFDRILLLSSGEIV 223

cbiO

PRK13642

energy-coupling factor transporter ATPase;

1-238

4.47e-20

energy-coupling factor transporter ATPase;

Pssm-ID: 184202 [Multi-domain] Cd Length: 277 Bit Score: 90.15 E-value: 4.47e-20

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   1 MTPRLSLRNITKRY---PGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQAR 77
Cdd:PRK13642    1 MNKILEVENLVFKYekeSDVNQLNGVSFSITKGEWVSIIGQNGSGKSTTARLIDGLFEEFEGKVKIDGELLTAENVWNLR 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  78 ElGIAMVHQH-FALFDTLSVTENVALGL-STGISAAE-IEREIRLLGEKYGLEV---DPAsvvmELSMGERQRVEILRAL 151
Cdd:PRK13642   81 R-KIGMVFQNpDNQFVGATVEDDVAFGMeNQGIPREEmIKRVDEALLAVNMLDFktrEPA----RLSGGQKQRVAVAGII 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 152 MTKPKLLILDEPTSVLTPQAVRKLFKTLHQLSSE-GVSILFISHKLDEIRElADRCVVLRAGKVVASVDPKAESEENLAR 230
Cdd:PRK13642  156 ALRPEIIILDESTSMLDPTGRQEIMRVIHEIKEKyQLTVLSITHDLDEAAS-SDRILVMKAGEIIKEAAPSELFATSEDM 234


                  ....*...
gi 2549828669 231 LMIGNDPP 238
Cdd:PRK13642  235 VEIGLDVP 242

znuC

PRK09544

high-affinity zinc transporter ATPase; Reviewed

1-196

5.61e-20

high-affinity zinc transporter ATPase; Reviewed

Pssm-ID: 181939 [Multi-domain] Cd Length: 251 Bit Score: 89.40 E-value: 5.61e-20

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   1 MTPRLSLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEIsfdghplgvETPAQARelg 80
Cdd:PRK09544    1 MTSLVSLENVSVSFGQRRVLSDVSLELKPGKILTLLGPNGAGKSTLVRVVLGLVAPDEGVI---------KRNGKLR--- 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  81 IAMVHQHFALFDTLSVTENVALGLSTGISAAEIEREIRLLGEKYGLEvdpaSVVMELSMGERQRVEILRALMTKPKLLIL 160
Cdd:PRK09544   69 IGYVPQKLYLDTTLPLTVNRFLRLRPGTKKEDILPALKRVQAGHLID----APMQKLSGGETQRVLLARALLNRPQLLVL 144

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 2549828669 161 DEPTSVLTPQAVRKLFKTLHQLSSE-GVSILFISHKL 196
Cdd:PRK09544  145 DEPTQGVDVNGQVALYDLIDQLRRElDCAVLMVSHDL 181

rim_protein

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...

1-220

9.46e-20

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]

Pssm-ID: 130324 [Multi-domain] Cd Length: 2272 Bit Score: 93.54 E-value: 9.46e-20

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669    1 MTPRLSLRNITKRYP--GITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHplGVETPAQARE 78
Cdd:TIGR01257  925 LVPGVCVKNLVKIFEpsGRPAVDRLNITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLVGGK--DIETNLDAVR 1002

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   79 LGIAMVHQHFALFDTLSVTENVAL-GLSTGISAAEIEREIRLLGEKYGLEVDPASVVMELSMGERQRVEILRALMTKPKL 157
Cdd:TIGR01257 1003 QSLGMCPQHNILFHHLTVAEHILFyAQLKGRSWEEAQLEMEAMLEDTGLHHKRNEEAQDLSGGMQRKLSVAIAFVGDAKV 1082

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2549828669  158 LILDEPTSVLTPQAVRKLFKTLHQLSSeGVSILFISHKLDEIRELADRCVVLRAGKVVASVDP 220
Cdd:TIGR01257 1083 VVLDEPTSGVDPYSRRSIWDLLLKYRS-GRTIIMSTHHMDEADLLGDRIAIISQGRLYCSGTP 1144

rim_protein

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...

2-212

1.19e-19

Pssm-ID: 130324 [Multi-domain] Cd Length: 2272 Bit Score: 93.15 E-value: 1.19e-19

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669    2 TPRLSLRNITKRYPGIT--ANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVEtpaqarel 79
Cdd:TIGR01257 1935 TDILRLNELTKVYSGTSspAVDRLCVGVRPGECFGLLGVNGAGKTTTFKMLTGDTTVTSGDATVAGKSILTN-------- 2006

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   80 gIAMVHQHF-------ALFDTLSVTENVAL-GLSTGISAAEIEREIRLLGEKYGLEVDPASVVMELSMGERQRVEILRAL 151
Cdd:TIGR01257 2007 -ISDVHQNMgycpqfdAIDDLLTGREHLYLyARLRGVPAEEIEKVANWSIQSLGLSLYADRLAGTYSGGNKRKLSTAIAL 2085

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2549828669  152 MTKPKLLILDEPTSVLTPQAVRKLFKTLHQLSSEGVSILFISHKLDEIRELADRCVVLRAG 212
Cdd:TIGR01257 2086 IGCPPLVLLDEPTTGMDPQARRMLWNTIVSIIREGRAVVLTSHSMEECEALCTRLAIMVKG 2146

cbiO

PRK13631

cobalt transporter ATP-binding subunit; Provisional

17-220

2.13e-19

cobalt transporter ATP-binding subunit; Provisional

Pssm-ID: 237451 [Multi-domain] Cd Length: 320 Bit Score: 89.14 E-value: 2.13e-19

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  17 ITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEIS----FDGHPLGVETPA---------QARELG--I 81
Cdd:PRK13631   39 LVALNNISYTFEKNKIYFIIGNSGSGKSTLVTHFNGLIKSKYGTIQvgdiYIGDKKNNHELItnpyskkikNFKELRrrV 118

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  82 AMVHQ--HFALF-DTLS---VTENVALGLSTGISAAEIEREIRLLGEKYG-LEVDPasvvMELSMGERQRVEILRALMTK 154
Cdd:PRK13631  119 SMVFQfpEYQLFkDTIEkdiMFGPVALGVKKSEAKKLAKFYLNKMGLDDSyLERSP----FGLSGGQKRRVAIAGILAIQ 194

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2549828669 155 PKLLILDEPTSVLTPQAVRKLFKTLHQLSSEGVSILFISHKLDEIRELADRCVVLRAGKVVASVDP 220
Cdd:PRK13631  195 PEILIFDEPTAGLDPKGEHEMMQLILDAKANNKTVFVITHTMEHVLEVADEVIVMDKGKILKTGTP 260

ABC_CcmA_heme_exporter

cd03231

Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ...

23-194

2.57e-19

Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.

Pssm-ID: 213198 [Multi-domain] Cd Length: 201 Bit Score: 86.01 E-value: 2.57e-19

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  23 VSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQARELgIAMVHQHfALFDTLSVTENV-- 100
Cdd:cd03231    19 LSFTLAAGEALQVTGPNGSGKTTLLRILAGLSPPLAGRVLLNGGPLDFQRDSIARGL-LYLGHAP-GIKTTLSVLENLrf 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 101 --ALGLSTGISAAEIEREIRllgekyGLEVDPASvvmELSMGERQRVEILRALMTKPKLLILDEPTSVLTPQAVRKLFKT 178
Cdd:cd03231    97 whADHSDEQVEEALARVGLN------GFEDRPVA---QLSAGQQRRVALARLLLSGRPLWILDEPTTALDKAGVARFAEA 167

                         170
                  ....*....|....*.
gi 2549828669 179 LHQLSSEGVSILFISH 194
Cdd:cd03231   168 MAGHCARGGMVVLTTH 183

cbiO

PRK13643

energy-coupling factor transporter ATPase;

23-220

2.64e-19

energy-coupling factor transporter ATPase;

Pssm-ID: 184203 [Multi-domain] Cd Length: 288 Bit Score: 88.25 E-value: 2.64e-19

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  23 VSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFdGHPLGVETPAQA------RELGIAMVHQHFALFDTlSV 96
Cdd:PRK13643   25 IDLEVKKGSYTALIGHTGSGKSTLLQHLNGLLQPTEGKVTV-GDIVVSSTSKQKeikpvrKKVGVVFQFPESQLFEE-TV 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  97 TENVALGLST-GISAAEIER----EIRLLG-EKYGLEVDPasvvMELSMGERQRVEILRALMTKPKLLILDEPTSVLTPQ 170
Cdd:PRK13643  103 LKDVAFGPQNfGIPKEKAEKiaaeKLEMVGlADEFWEKSP----FELSGGQMRRVAIAGILAMEPEVLVLDEPTAGLDPK 178

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2549828669 171 A---VRKLFKTLHQlssEGVSILFISHKLDEIRELADRCVVLRAGKVVASVDP 220
Cdd:PRK13643  179 ArieMMQLFESIHQ---SGQTVVLVTHLMDDVADYADYVYLLEKGHIISCGTP 228

PRK13540

cytochrome c biogenesis protein CcmA; Provisional

21-195

2.92e-19

cytochrome c biogenesis protein CcmA; Provisional

Pssm-ID: 184127 [Multi-domain] Cd Length: 200 Bit Score: 85.77 E-value: 2.92e-19

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  21 DHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQARELgiAMVHQHFALFDTLSVTENV 100
Cdd:PRK13540   18 QQISFHLPAGGLLHLKGSNGAGKTTLLKLIAGLLNPEKGEILFERQSIKKDLCTYQKQL--CFVGHRSGINPYLTLRENC 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 101 ALGLSTGISAAEIEREIRLLGEKYGLEVdPASVvmeLSMGERQRVEILRALMTKPKLLILDEPTSVLTPQAVRKLFKTLH 180
Cdd:PRK13540   96 LYDIHFSPGAVGITELCRLFSLEHLIDY-PCGL---LSSGQKRQVALLRLWMSKAKLWLLDEPLVALDELSLLTIITKIQ 171

                         170
                  ....*....|....*
gi 2549828669 181 QLSSEGVSILFISHK 195
Cdd:PRK13540  172 EHRAKGGAVLLTSHQ 186

PRK14258

phosphate ABC transporter ATP-binding protein; Provisional

1-204

3.28e-19

phosphate ABC transporter ATP-binding protein; Provisional

Pssm-ID: 184593 [Multi-domain] Cd Length: 261 Bit Score: 87.40 E-value: 3.28e-19

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   1 MTPRLSLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIyGAARPDEGEISFDGHplgVETPAQA---R 77
Cdd:PRK14258    4 LIPAIKVNNLSFYYDTQKILEGVSMEIYQSKVTAIIGPSGCGKSTFLKCL-NRMNELESEVRVEGR---VEFFNQNiyeR 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  78 ELGI-------AMVHQHFALFdTLSVTENVALGL---------------STGISAAEIEREIRLLGEKYGLEvdpasvvm 135
Cdd:PRK14258   80 RVNLnrlrrqvSMVHPKPNLF-PMSVYDNVAYGVkivgwrpkleiddivESALKDADLWDEIKHKIHKSALD-------- 150

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2549828669 136 eLSMGERQRVEILRALMTKPKLLILDEPTSVLTPQAVRKLFKTLH--QLSSEgVSILFISHKLDEIRELAD 204
Cdd:PRK14258  151 -LSGGQQQRLCIARALAVKPKVLLMDEPCFGLDPIASMKVESLIQslRLRSE-LTMVIVSHNLHQVSRLSD 219

PRK15093

peptide ABC transporter ATP-binding protein SapD;

3-226

4.13e-19

peptide ABC transporter ATP-binding protein SapD;

Pssm-ID: 185049 [Multi-domain] Cd Length: 330 Bit Score: 88.32 E-value: 4.13e-19

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   3 PRLSLRNITKRYPG----ITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARpDEGEIS-----FDGHPLGVETP 73
Cdd:PRK15093    2 PLLDIRNLTIEFKTsdgwVKAVDRVSMTLTEGEIRGLVGESGSGKSLIAKAICGVTK-DNWRVTadrmrFDDIDLLRLSP 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  74 AQAREL---GIAMVHQHFAlfDTLSVTENVALGLSTGISAAEIE------------REIRLLgEKYGLEvDPASVV---- 134
Cdd:PRK15093   81 RERRKLvghNVSMIFQEPQ--SCLDPSERVGRQLMQNIPGWTYKgrwwqrfgwrkrRAIELL-HRVGIK-DHKDAMrsfp 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 135 MELSMGERQRVEILRALMTKPKLLILDEPTSVLTPQAVRKLFKTLHQLS-SEGVSILFISHKLDEIRELADRCVVLRAGK 213
Cdd:PRK15093  157 YELTEGECQKVMIAIALANQPRLLIADEPTNAMEPTTQAQIFRLLTRLNqNNNTTILLISHDLQMLSQWADKINVLYCGQ 236

                         250
                  ....*....|...
gi 2549828669 214 VVASvdpkAESEE 226
Cdd:PRK15093  237 TVET----APSKE 245

PRK14247

phosphate ABC transporter ATP-binding protein; Provisional

4-215

4.25e-19

phosphate ABC transporter ATP-binding protein; Provisional

Pssm-ID: 172735 [Multi-domain] Cd Length: 250 Bit Score: 86.89 E-value: 4.25e-19

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   4 RLSLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKI------IYGAARPdEGEISFDGHPLgVETPAQAR 77
Cdd:PRK14247    3 KIEIRDLKVSFGQVEVLDGVNLEIPDNTITALMGPSGSGKSTLLRVfnrlieLYPEARV-SGEVYLDGQDI-FKMDVIEL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  78 ELGIAMVHQHFALFDTLSVTENVALGLSTG---ISAAEIEREIRLLGEKYGL--EVD-----PASvvmELSMGERQRVEI 147
Cdd:PRK14247   81 RRRVQMVFQIPNPIPNLSIFENVALGLKLNrlvKSKKELQERVRWALEKAQLwdEVKdrldaPAG---KLSGGQQQRLCI 157

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2549828669 148 LRALMTKPKLLILDEPTSVLTPQAVRKLFKTLHQLSSEgVSILFISHKLDEIRELADRCVVLRAGKVV 215
Cdd:PRK14247  158 ARALAFQPEVLLADEPTANLDPENTAKIESLFLELKKD-MTIVLVTHFPQQAARISDYVAFLYKGQIV 224

PRK13538

cytochrome c biogenesis heme-transporting ATPase CcmA;

21-194

1.22e-18

cytochrome c biogenesis heme-transporting ATPase CcmA;

Pssm-ID: 184125 [Multi-domain] Cd Length: 204 Bit Score: 84.09 E-value: 1.22e-18

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  21 DHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQAREL---GiamvHQHfALFDTLSVT 97
Cdd:PRK13538   18 SGLSFTLNAGELVQIEGPNGAGKTSLLRILAGLARPDAGEVLWQGEPIRRQRDEYHQDLlylG----HQP-GIKTELTAL 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  98 ENV--ALGLSTGISAAEIEREIRLLGEKyGLEVDPASVvmeLSMGERQRVEILRALMTKPKLLILDEPTSVLTPQAVRKL 175
Cdd:PRK13538   93 ENLrfYQRLHGPGDDEALWEALAQVGLA-GFEDVPVRQ---LSAGQQRRVALARLWLTRAPLWILDEPFTAIDKQGVARL 168

                         170
                  ....*....|....*....
gi 2549828669 176 FKTLHQLSSEGVSILFISH 194
Cdd:PRK13538  169 EALLAQHAEQGGMVILTTH 187

ABC_DR_subfamily_A

cd03230

ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ...

261-469

1.30e-18

Pssm-ID: 213197 [Multi-domain] Cd Length: 173 Bit Score: 83.22 E-value: 1.30e-18

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 261 GSTRVcgIDNVSLAVRAGEIVGIAGISGNGQARFMAAASGEYLCEADRVLLFNSPVGELDTHARRISGlrYVPEqrlgHA 340
Cdd:cd03230    11 GKKTA--LDDISLTVEKGEIYGLLGPNGAGKTTLIKIILGLLKPDSGEIKVLGKDIKKEPEEVKRRIG--YLPE----EP 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 341 AVPElSLTANTYLTgdslvrsgfilrdrarsfanlvierfhvktpnaekaagsLSGGNLQKFIMGREILNRPRVLLVHQP 420
Cdd:cd03230    83 SLYE-NLTVRENLK---------------------------------------LSGGMKQRLALAQALLHDPELLILDEP 122

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 2549828669 421 TWGVDVGAAAVIRNSLIRLRDDGAAIIVVSEEIDELFEISDRIAVMYRG 469
Cdd:cd03230   123 TSGLDPESRREFWELLRELKKEGKTILLSSHILEEAERLCDRVAILNNG 171

PRK10522

multidrug transporter membrane component/ATP-binding component; Provisional

4-213

1.50e-18

multidrug transporter membrane component/ATP-binding component; Provisional

Pssm-ID: 236707 [Multi-domain] Cd Length: 547 Bit Score: 88.49 E-value: 1.50e-18

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   4 RLSLRNITKRYPGIT-ANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQARELgIA 82
Cdd:PRK10522  322 TLELRNVTFAYQDNGfSVGPINLTIKRGELLFLIGGNGSGKSTLAMLLTGLYQPQSGEILLDGKPVTAEQPEDYRKL-FS 400

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  83 MVHQHFALFDTLSVTENVAlglstgISAAEIEREIRLLGEKYGLEVDPASVV-MELSMGERQRVEILRALMTKPKLLILD 161
Cdd:PRK10522  401 AVFTDFHLFDQLLGPEGKP------ANPALVEKWLERLKMAHKLELEDGRISnLKLSKGQKKRLALLLALAEERDILLLD 474

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2549828669 162 EPTSVLTPQaVRKLF--KTLHQLSSEGVSILFISHKlDEIRELADRCVVLRAGK 213
Cdd:PRK10522  475 EWAADQDPH-FRREFyqVLLPLLQEMGKTIFAISHD-DHYFIHADRLLEMRNGQ 526

PRK11174

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed

23-215

2.28e-18

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed

Pssm-ID: 236870 [Multi-domain] Cd Length: 588 Bit Score: 87.98 E-value: 2.28e-18

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  23 VSLDIAPGEVLAILGENGAGKSTLMKIIYGAArPDEGEISFDGHPLGVETPAQARELgIAMVHQHFALFDTlSVTENVAL 102
Cdd:PRK11174  369 LNFTLPAGQRIALVGPSGAGKTSLLNALLGFL-PYQGSLKINGIELRELDPESWRKH-LSWVGQNPQLPHG-TLRDNVLL 445

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 103 GLSTgISAAEIEReirLLGEKYGLEVDPA------SVVME----LSMGERQRVEILRALMTKPKLLILDEPTSVLTPQAV 172
Cdd:PRK11174  446 GNPD-ASDEQLQQ---ALENAWVSEFLPLlpqgldTPIGDqaagLSVGQAQRLALARALLQPCQLLLLDEPTASLDAHSE 521

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 2549828669 173 RKLFKTLHQLsSEGVSILFISHKLDEIRELaDRCVVLRAGKVV 215
Cdd:PRK11174  522 QLVMQALNAA-SRRQTTLMVTHQLEDLAQW-DQIWVMQDGQIV 562

PRK10790

SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;

22-215

2.53e-18

SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;

Pssm-ID: 182733 [Multi-domain] Cd Length: 592 Bit Score: 87.85 E-value: 2.53e-18

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  22 HVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQARElGIAMVHQH-FALFDTLSVteNV 100
Cdd:PRK10790  359 NINLSVPSRGFVALVGHTGSGKSTLASLLMGYYPLTEGEIRLDGRPLSSLSHSVLRQ-GVAMVQQDpVVLADTFLA--NV 435

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 101 ALG-----------LSTgISAAEIEREI-----RLLGEKYGlevdpasvvmELSMGERQRVEILRALMTKPKLLILDEPT 164
Cdd:PRK10790  436 TLGrdiseeqvwqaLET-VQLAELARSLpdglyTPLGEQGN----------NLSVGQKQLLALARVLVQTPQILILDEAT 504

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2549828669 165 SVL---TPQAVRKLFKTLHQLSsegvSILFISHKLDEIRElADRCVVLRAGKVV 215
Cdd:PRK10790  505 ANIdsgTEQAIQQALAAVREHT----TLVVIAHRLSTIVE-ADTILVLHRGQAV 553

type_I_sec_PrtD

TIGR01842

type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in ...

4-214

2.87e-18

type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. [Protein fate, Protein and peptide secretion and trafficking]

Pssm-ID: 200134 [Multi-domain] Cd Length: 544 Bit Score: 87.79 E-value: 2.87e-18

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   4 RLSLRNITKRYPG---ITANDhVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPaqaRELG 80
Cdd:TIGR01842 316 HLSVENVTIVPPGgkkPTLRG-ISFSLQAGEALAIIGPSGSGKSTLARLIVGIWPPTSGSVRLDGADLKQWDR---ETFG 391

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  81 --IAMVHQHFALFDTlSVTENVA-----LGLSTGISAAEI---EREIRLLGEKYGLEVDPASVvmELSMGERQRVEILRA 150
Cdd:TIGR01842 392 khIGYLPQDVELFPG-TVAENIArfgenADPEKIIEAAKLagvHELILRLPDGYDTVIGPGGA--TLSGGQRQRIALARA 468

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2549828669 151 LMTKPKLLILDEPTSVLTPQAVRKLFKTLHQLSSEGVSILFISHKLDEIrELADRCVVLRAGKV 214
Cdd:TIGR01842 469 LYGDPKLVVLDEPNSNLDEEGEQALANAIKALKARGITVVVITHRPSLL-GCVDKILVLQDGRI 531

btuD

PRK09536

corrinoid ABC transporter ATPase; Reviewed

3-239

3.48e-18

corrinoid ABC transporter ATPase; Reviewed

Pssm-ID: 236554 [Multi-domain] Cd Length: 402 Bit Score: 86.43 E-value: 3.48e-18

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   3 PRLSLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLgveTPAQARELG-- 80
Cdd:PRK09536    2 PMIDVSDLSVEFGDTTVLDGVDLSVREGSLVGLVGPNGAGKTTLLRAINGTLTPTAGTVLVAGDDV---EALSARAASrr 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  81 IAMVHQHFALFDTLSVTENVALG-------LSTGISA--AEIEREIrllgEKYGLEVDPASVVMELSMGERQRVEILRAL 151
Cdd:PRK09536   79 VASVPQDTSLSFEFDVRQVVEMGrtphrsrFDTWTETdrAAVERAM----ERTGVAQFADRPVTSLSGGERQRVLLARAL 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 152 MTKPKLLILDEPTSVL-TPQAVRKLfKTLHQLSSEGVSILFISHKLDEIRELADRCVVLRAGKVVASVDPKAE-SEENL- 228
Cdd:PRK09536  155 AQATPVLLLDEPTASLdINHQVRTL-ELVRRLVDDGKTAVAAIHDLDLAARYCDELVLLADGRVRAAGPPADVlTADTLr 233

                         250
                  ....*....|....*
gi 2549828669 229 ----ARLMIGNDPPT 239
Cdd:PRK09536  234 aafdARTAVGTDPAT 248

ABC2_perm_RbbA

ribosome-associated ATPase/putative transporter RbbA;

6-469

4.52e-18

ribosome-associated ATPase/putative transporter RbbA;

Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 87.49 E-value: 4.52e-18

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   6 SLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLgvetpAQARELgiAMVH 85
Cdd:NF033858    3 RLEGVSHRYGKTVALDDVSLDIPAGCMVGLIGPDGVGKSSLLSLIAGARKIQQGRVEVLGGDM-----ADARHR--RAVC 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  86 QHFA---------LFDTLSVTENVAL-GLSTGISAAEIEREIRLLGEKYGLE--VD-PASvvmELSMGERQRVEILRALM 152
Cdd:NF033858   76 PRIAympqglgknLYPTLSVFENLDFfGRLFGQDAAERRRRIDELLRATGLApfADrPAG---KLSGGMKQKLGLCCALI 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 153 TKPKLLILDEPTSVLTPQAvRKLFKTL---HQLSSEGVSILFISHKLDEIrELADRCVVLRAGKVVASVDPK-------A 222
Cdd:NF033858  153 HDPDLLILDEPTTGVDPLS-RRQFWELidrIRAERPGMSVLVATAYMEEA-ERFDWLVAMDAGRVLATGTPAellartgA 230

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 223 ES-EENLARLMigndPPTVREGTA----------KAGEVVFEMRHVsapgsTRVCG----IDNVSLAVRAGEIVGIAGIS 287
Cdd:NF033858  231 DTlEAAFIALL----PEEKRRGHQpvvipprpadDDDEPAIEARGL-----TMRFGdftaVDHVSFRIRRGEIFGFLGSN 301

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 288 GNGQARFM-------AAASGEylceadrVLLFNSPV---------------------GE------LDTHARrisgLRYVP 333
Cdd:NF033858  302 GCGKSTTMkmltgllPASEGE-------AWLFGQPVdagdiatrrrvgymsqafslyGEltvrqnLELHAR----LFHLP 370

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 334 EQRLGhAAVPELsltantyltgdslvrsgfilrdrarsfanlvIERFHVkTPNAEKAAGSLSGGNLQKFIMGREILNRPR 413
Cdd:NF033858  371 AAEIA-ARVAEM-------------------------------LERFDL-ADVADALPDSLPLGIRQRLSLAVAVIHKPE 417

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2549828669 414 VLLVHQPTWGVDVGAaaviRNS----LIRL-RDDGAAIIVVSEEIDELfEISDRIAVMYRG 469
Cdd:NF033858  418 LLILDEPTSGVDPVA----RDMfwrlLIELsREDGVTIFISTHFMNEA-ERCDRISLMHAG 473

PRK10789

SmdA family multidrug ABC transporter permease/ATP-binding protein;

13-215

6.26e-18

SmdA family multidrug ABC transporter permease/ATP-binding protein;

Pssm-ID: 182732 [Multi-domain] Cd Length: 569 Bit Score: 86.69 E-value: 6.26e-18

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  13 RYPGIT--ANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLgveTPAQAREL--GIAMVHQHF 88
Cdd:PRK10789  322 TYPQTDhpALENVNFTLKPGQMLGICGPTGSGKSTLLSLIQRHFDVSEGDIRFHDIPL---TKLQLDSWrsRLAVVSQTP 398

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  89 ALFDTlSVTENVALGlSTGISAAEIEREIRL---------LGEKYGLEVDPASVVmeLSMGERQRVEILRALMTKPKLLI 159
Cdd:PRK10789  399 FLFSD-TVANNIALG-RPDATQQEIEHVARLasvhddilrLPQGYDTEVGERGVM--LSGGQKQRISIARALLLNAEILI 474

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2549828669 160 LDEPTSVLTPQAVRKLFKTLHQLsSEGVSILFISHKLDEIRElADRCVVLRAGKVV 215
Cdd:PRK10789  475 LDDALSAVDGRTEHQILHNLRQW-GEGRTVIISAHRLSALTE-ASEILVMQHGHIA 528

MK0520

COG2401

ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction ...

21-215

1.08e-17

ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only];

Pssm-ID: 441957 [Multi-domain] Cd Length: 222 Bit Score: 81.93 E-value: 1.08e-17

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  21 DHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAA--RPDEGEISFDGHPLGVETPaqarelgiaMVHQHFALFDTLSVTE 98
Cdd:COG2401    47 RDLNLEIEPGEIVLIVGASGSGKSTLLRLLAGALkgTPVAGCVDVPDNQFGREAS---------LIDAIGRKGDFKDAVE 117

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  99 NVAL-GLSTGIsaaeiereirLLGEKYGlevdpasvvmELSMGERQRVEILRALMTKPKLLILDEPTSVLTPQAVRKLFK 177
Cdd:COG2401   118 LLNAvGLSDAV----------LWLRRFK----------ELSTGQKFRFRLALLLAERPKLLVIDEFCSHLDRQTAKRVAR 177

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 2549828669 178 TLHQLSSE-GVSILFISHKLDEIRELA-DRCVVLRAGKVV 215
Cdd:COG2401   178 NLQKLARRaGITLVVATHHYDVIDDLQpDLLIFVGYGGVP 217

dppD

PRK11022

dipeptide transporter ATP-binding subunit; Provisional

19-217

1.34e-17

dipeptide transporter ATP-binding subunit; Provisional

Pssm-ID: 182906 [Multi-domain] Cd Length: 326 Bit Score: 83.64 E-value: 1.34e-17

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  19 ANDHVSLDIAPGEVLAILGENGAGKS----TLMKIIYGAARPDEGEISFDGHPLGVETPAQAREL---GIAMVHQH---- 87
Cdd:PRK11022   22 AVDRISYSVKQGEVVGIVGESGSGKSvsslAIMGLIDYPGRVMAEKLEFNGQDLQRISEKERRNLvgaEVAMIFQDpmts 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  88 --------FALFDTLSVTENvalglstGISAAEIEREIRLLgEKYGLEvDPASVV----MELSMGERQRVEILRALMTKP 155
Cdd:PRK11022  102 lnpcytvgFQIMEAIKVHQG-------GNKKTRRQRAIDLL-NQVGIP-DPASRLdvypHQLSGGMSQRVMIAMAIACRP 172

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2549828669 156 KLLILDEPTSVL--TPQA-VRKLFKTLHQlsSEGVSILFISHKLDEIRELADRCVVLRAGKVVAS 217
Cdd:PRK11022  173 KLLIADEPTTALdvTIQAqIIELLLELQQ--KENMALVLITHDLALVAEAAHKIIVMYAGQVVET 235

cbiO

PRK13634

cobalt transporter ATP-binding subunit; Provisional

22-221

1.82e-17

cobalt transporter ATP-binding subunit; Provisional

Pssm-ID: 237454 [Multi-domain] Cd Length: 290 Bit Score: 82.76 E-value: 1.82e-17

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  22 HVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVET-PAQAREL--GIAMVHQhFA---LFDTlS 95
Cdd:PRK13634   25 DVNVSIPSGSYVAIIGHTGSGKSTLLQHLNGLLQPTSGTVTIGERVITAGKkNKKLKPLrkKVGIVFQ-FPehqLFEE-T 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  96 VTENVALG-LSTGISAAEIEREIRLLGEKYGLevdPASVV----MELSMGERQRVEILRALMTKPKLLILDEPTSVLTPQ 170
Cdd:PRK13634  103 VEKDICFGpMNFGVSEEDAKQKAREMIELVGL---PEELLarspFELSGGQMRRVAIAGVLAMEPEVLVLDEPTAGLDPK 179

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2549828669 171 AvRK----LFKTLHQlsSEGVSILFISHKLDEIRELADRCVVLRAGKVVASVDPK 221
Cdd:PRK13634  180 G-RKemmeMFYKLHK--EKGLTTVLVTHSMEDAARYADQIVVMHKGTVFLQGTPR 231

cbiO

PRK13646

energy-coupling factor transporter ATPase;

19-222

2.37e-17

energy-coupling factor transporter ATPase;

Pssm-ID: 184205 [Multi-domain] Cd Length: 286 Bit Score: 82.52 E-value: 2.37e-17

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  19 ANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVET------PAQARelgIAMVHQ--HFAL 90
Cdd:PRK13646   22 AIHDVNTEFEQGKYYAIVGQTGSGKSTLIQNINALLKPTTGTVTVDDITITHKTkdkyirPVRKR---IGMVFQfpESQL 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  91 FDTlSVTENVALGLST-GISAAEI-EREIRLLGEkYGLEVDpasvVMELS---M--GERQRVEILRALMTKPKLLILDEP 163
Cdd:PRK13646   99 FED-TVEREIIFGPKNfKMNLDEVkNYAHRLLMD-LGFSRD----VMSQSpfqMsgGQMRKIAIVSILAMNPDIIVLDEP 172

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 164 TSVLTPQAVRKLFKTLHQLSSE-GVSILFISHKLDEIRELADRCVVLRAGKVVASVDPKA 222
Cdd:PRK13646  173 TAGLDPQSKRQVMRLLKSLQTDeNKTIILVSHDMNEVARYADEVIVMKEGSIVSQTSPKE 232

PRK14246

phosphate ABC transporter ATP-binding protein; Provisional

23-215

3.38e-17

phosphate ABC transporter ATP-binding protein; Provisional

Pssm-ID: 172734 [Multi-domain] Cd Length: 257 Bit Score: 81.25 E-value: 3.38e-17

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  23 VSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPL-------GVETPAQARELGiaMVHQHFALFDTLS 95
Cdd:PRK14246   29 ITIKIPNNSIFGIMGPSGSGKSTLLKVLNRLIEIYDSKIKVDGKVLyfgkdifQIDAIKLRKEVG--MVFQQPNPFPHLS 106

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  96 VTENVALGL-STGIS--------AAEIEREIRLLGEKYGLEVDPASvvmELSMGERQRVEILRALMTKPKLLILDEPTSV 166
Cdd:PRK14246  107 IYDNIAYPLkSHGIKekreikkiVEECLRKVGLWKEVYDRLNSPAS---QLSGGQQQRLTIARALALKPKVLLMDEPTSM 183

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 2549828669 167 LTPQAVRKLFKTLHQLSSEgVSILFISHKLDEIRELADRCVVLRAGKVV 215
Cdd:PRK14246  184 IDIVNSQAIEKLITELKNE-IAIVIVSHNPQQVARVADYVAFLYNGELV 231

ABCC_NFT1

cd03369

ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type ...

4-215

6.95e-17

ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type transporter 1). NFT1 belongs to the MRP (multidrug resistance-associated protein) family of ABC transporters. Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions such as glutathione, glucuronate, and sulfate.

Pssm-ID: 213269 [Multi-domain] Cd Length: 207 Bit Score: 79.38 E-value: 6.95e-17

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   4 RLSLRNITKRY----PGITANdhVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGvETPAQAREL 79
Cdd:cd03369     6 EIEVENLSVRYapdlPPVLKN--VSFKVKAGEKIGIVGRTGAGKSTLILALFRFLEAEEGKIEIDGIDIS-TIPLEDLRS 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  80 GIAMVHQHFALFDTlSVTENvaLGLSTGISAAEIEREIRLLGEkyGLEvdpasvvmeLSMGERQRVEILRALMTKPKLLI 159
Cdd:cd03369    83 SLTIIPQDPTLFSG-TIRSN--LDPFDEYSDEEIYGALRVSEG--GLN---------LSQGQRQLLCLARALLKRPRVLV 148

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2549828669 160 LDEPTSVLTPQAVRKLFKTLHQLSSeGVSILFISHKLDEIRELaDRCVVLRAGKVV 215
Cdd:cd03369   149 LDEATASIDYATDALIQKTIREEFT-NSTILTIAHRLRTIIDY-DKILVMDAGEVK 202

oppD

PRK09473

oligopeptide transporter ATP-binding component; Provisional

17-213

7.86e-17

oligopeptide transporter ATP-binding component; Provisional

Pssm-ID: 181888 [Multi-domain] Cd Length: 330 Bit Score: 81.69 E-value: 7.86e-17

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  17 ITANDHVSLDIAPGEVLAILGENGAGKS----TLMKIIYGAARPdEGEISFDGHPLgVETPAQA----RELGIAMVHQH- 87
Cdd:PRK09473   29 VTAVNDLNFSLRAGETLGIVGESGSGKSqtafALMGLLAANGRI-GGSATFNGREI-LNLPEKElnklRAEQISMIFQDp 106

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  88 -FALFDTLSVTENVA--LGLSTGISAAE-IEREIRLLGekyGLEVDPASVVM-----ELSMGERQRVEILRALMTKPKLL 158
Cdd:PRK09473  107 mTSLNPYMRVGEQLMevLMLHKGMSKAEaFEESVRMLD---AVKMPEARKRMkmyphEFSGGMRQRVMIAMALLCRPKLL 183

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2549828669 159 ILDEPTSVL--TPQAvrKLFKTLHQLSSE-GVSILFISHKLDEIRELADRCVVLRAGK 213
Cdd:PRK09473  184 IADEPTTALdvTVQA--QIMTLLNELKREfNTAIIMITHDLGVVAGICDKVLVMYAGR 239

cbiO

PRK13645

energy-coupling factor transporter ATPase;

7-238

1.00e-16

energy-coupling factor transporter ATPase;

Pssm-ID: 184204 [Multi-domain] Cd Length: 289 Bit Score: 80.44 E-value: 1.00e-16

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   7 LRNITKRYPGIT-----ANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGH--PLGV----ETPAQ 75
Cdd:PRK13645    9 LDNVSYTYAKKTpfefkALNNTSLTFKKNKVTCVIGTTGSGKSTMIQLTNGLIISETGQTIVGDYaiPANLkkikEVKRL 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  76 ARELGIAMVHQHFALFDTlSVTENVALG-LSTGISAAEIEREIRLLGEKYGLEVDPAS-VVMELSMGERQRVEILRALMT 153
Cdd:PRK13645   89 RKEIGLVFQFPEYQLFQE-TIEKDIAFGpVNLGENKQEAYKKVPELLKLVQLPEDYVKrSPFELSGGQKRRVALAGIIAM 167

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 154 KPKLLILDEPTSVLTPQAVRKLFKTLHQLSSE-GVSILFISHKLDEIRELADRCVVLRAGKVVASVDPKA--ESEENLAR 230
Cdd:PRK13645  168 DGNTLVLDEPTGGLDPKGEEDFINLFERLNKEyKKRIIMVTHNMDQVLRIADEVIVMHEGKVISIGSPFEifSNQELLTK 247


                  ....*...
gi 2549828669 231 LMIgnDPP 238
Cdd:PRK13645  248 IEI--DPP 253

PRK10261

glutathione transporter ATP-binding protein; Provisional

3-227

1.03e-16

glutathione transporter ATP-binding protein; Provisional

Pssm-ID: 182342 [Multi-domain] Cd Length: 623 Bit Score: 82.98 E-value: 1.03e-16

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   3 PRLSLRNITKRYP-----------GITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVE 71
Cdd:PRK10261  312 PILQVRNLVTRFPlrsgllnrvtrEVHAVEKVSFDLWPGETLSLVGESGSGKSTTGRALLRLVESQGGEIIFNGQRIDTL 391

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  72 TPAQAREL--GIAMVHQH-FALFDT-----LSVTENVAL-GLSTGISAAeieREIRLLGEKYGLEVDPA-SVVMELSMGE 141
Cdd:PRK10261  392 SPGKLQALrrDIQFIFQDpYASLDPrqtvgDSIMEPLRVhGLLPGKAAA---ARVAWLLERVGLLPEHAwRYPHEFSGGQ 468

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 142 RQRVEILRALMTKPKLLILDEPTSVLTPQAVRKLFKTLHQLSSE-GVSILFISHKLDEIRELADRCVVLRAGKVVaSVDP 220
Cdd:PRK10261  469 RQRICIARALALNPKVIIADEAVSALDVSIRGQIINLLLDLQRDfGIAYLFISHDMAVVERISHRVAVMYLGQIV-EIGP 547


                  ....*..
gi 2549828669 221 KAESEEN 227
Cdd:PRK10261  548 RRAVFEN 554

ABCG_PDR_domain2

cd03232

Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding ...

27-215

1.76e-16

Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213199 [Multi-domain] Cd Length: 192 Bit Score: 77.67 E-value: 1.76e-16

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  27 IAPGEVLAILGENGAGKSTLMKIIygAARPD----EGEISFDGHPLGVETPAQarelgIAMVHQHFALFDTLSVTEnval 102
Cdd:cd03232    30 VKPGTLTALMGESGAGKTTLLDVL--AGRKTagviTGEILINGRPLDKNFQRS-----TGYVEQQDVHSPNLTVRE---- 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 103 glSTGISAAeiereIRllgekyglevdpasvvmELSMGERQRVEILRALMTKPKLLILDEPTSVLTPQAVRKLFKTLHQL 182
Cdd:cd03232    99 --ALRFSAL-----LR-----------------GLSVEQRKRLTIGVELAAKPSILFLDEPTSGLDSQAAYNIVRFLKKL 154

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 2549828669 183 SSEGVSIL-FISHKLDEIRELADRCVVL-RAGKVV 215
Cdd:cd03232   155 ADSGQAILcTIHQPSASIFEKFDRLLLLkRGGKTV 189

ycf16

CHL00131

sulfate ABC transporter protein; Validated

23-215

2.58e-16

sulfate ABC transporter protein; Validated

Pssm-ID: 214372 [Multi-domain] Cd Length: 252 Bit Score: 78.53 E-value: 2.58e-16

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  23 VSLDIAPGEVLAILGENGAGKSTLMKIIygAARPD----EGEISFDGHPLGVETPAQARELGIAMVHQHfalfdTLSVte 98
Cdd:CHL00131   26 LNLSINKGEIHAIMGPNGSGKSTLSKVI--AGHPAykilEGDILFKGESILDLEPEERAHLGIFLAFQY-----PIEI-- 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  99 nvalglsTGISAAEIEREIRLLGEK-YGL-EVDPAS-----------VVME-----------LSMGERQRVEILRALMTK 154
Cdd:CHL00131   97 -------PGVSNADFLRLAYNSKRKfQGLpELDPLEfleiineklklVGMDpsflsrnvnegFSGGEKKRNEILQMALLD 169

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2549828669 155 PKLLILDEPTSVLTPQAVRKLFKTLHQLSSEGVSILFISHK---LDEIRelADRCVVLRAGKVV 215
Cdd:CHL00131  170 SELAILDETDSGLDIDALKIIAEGINKLMTSENSIILITHYqrlLDYIK--PDYVHVMQNGKII 231

PRK13539

cytochrome c biogenesis protein CcmA; Provisional

3-179

3.09e-16

cytochrome c biogenesis protein CcmA; Provisional

Pssm-ID: 237421 [Multi-domain] Cd Length: 207 Bit Score: 77.22 E-value: 3.09e-16

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   3 PRLSLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPA-QARELGi 81
Cdd:PRK13539    1 MMLEGEDLACVRGGRVLFSGLSFTLAAGEALVLTGPNGSGKTTLLRLIAGLLPPAAGTIKLDGGDIDDPDVAeACHYLG- 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  82 amvHQHfALFDTLSVTENVAL------GLSTGISAAeIER-EIRLLGE-KYGlevdpasvvmELSMGERQRVEILRALMT 153
Cdd:PRK13539   80 ---HRN-AMKPALTVAENLEFwaaflgGEELDIAAA-LEAvGLAPLAHlPFG----------YLSAGQKRRVALARLLVS 144

                         170       180
                  ....*....|....*....|....*.
gi 2549828669 154 KPKLLILDEPTSVLTPQAVRkLFKTL 179
Cdd:PRK13539  145 NRPIWILDEPTAALDAAAVA-LFAEL 169

PRK14267

phosphate ABC transporter ATP-binding protein; Provisional

23-227

3.43e-16

phosphate ABC transporter ATP-binding protein; Provisional

Pssm-ID: 184596 [Multi-domain] Cd Length: 253 Bit Score: 78.35 E-value: 3.43e-16

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  23 VSLDIAPGEVLAILGENGAGKSTLMKI------IYGAARPdEGEISFDGHPLGVE--TPAQARElGIAMVHQHFALFDTL 94
Cdd:PRK14267   23 VDLKIPQNGVFALMGPSGCGKSTLLRTfnrlleLNEEARV-EGEVRLFGRNIYSPdvDPIEVRR-EVGMVFQYPNPFPHL 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  95 SVTENVALGLSTG---ISAAEIEREIRLLGEKYGL--EV-----DPASvvmELSMGERQRVEILRALMTKPKLLILDEPT 164
Cdd:PRK14267  101 TIYDNVAIGVKLNglvKSKKELDERVEWALKKAALwdEVkdrlnDYPS---NLSGGQRQRLVIARALAMKPKILLMDEPT 177

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2549828669 165 SVLTPQAVRKLFKTLHQLSSEgVSILFISHKLDEIRELADRCVVLRAGKVVaSVDPKAESEEN 227
Cdd:PRK14267  178 ANIDPVGTAKIEELLFELKKE-YTIVLVTHSPAQAARVSDYVAFLYLGKLI-EVGPTRKVFEN 238

PRK11147

ABC transporter ATPase component; Reviewed

21-215

5.40e-16

ABC transporter ATPase component; Reviewed

Pssm-ID: 236861 [Multi-domain] Cd Length: 635 Bit Score: 80.76 E-value: 5.40e-16

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  21 DHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFdghplgvetpaqARELGIAMVHQHFALFDTLSVTENV 100
Cdd:PRK11147   20 DNAELHIEDNERVCLVGRNGAGKSTLMKILNGEVLLDDGRIIY------------EQDLIVARLQQDPPRNVEGTVYDFV 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 101 ALGLSTGISAAEIEREI-RLLGEKYG--------------------------------LEVDPASVVMELSMGERQRVEI 147
Cdd:PRK11147   88 AEGIEEQAEYLKRYHDIsHLVETDPSeknlnelaklqeqldhhnlwqlenrinevlaqLGLDPDAALSSLSGGWLRKAAL 167

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2549828669 148 LRALMTKPKLLILDEPTSVLTPQAVRKLFKTLhqLSSEGvSILFISHKLDEIRELADRCVVLRAGKVV 215
Cdd:PRK11147  168 GRALVSNPDVLLLDEPTNHLDIETIEWLEGFL--KTFQG-SIIFISHDRSFIRNMATRIVDLDRGKLV 232

ABC_TM1139_LivF_branched

cd03224

ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ...

268-469

7.22e-16

Pssm-ID: 213191 [Multi-domain] Cd Length: 222 Bit Score: 76.70 E-value: 7.22e-16

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 268 IDNVSLAVRAGEIVGIAGISGNGQARFMAAASGEYLCEADRVLLFNSPVGELDTHARRISGLRYVPEqrlGHAAVPELSL 347
Cdd:cd03224    16 LFGVSLTVPEGEIVALLGRNGAGKTTLLKTIMGLLPPRSGSIRFDGRDITGLPPHERARAGIGYVPE---GRRIFPELTV 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 348 TANtyltgdslVRSGFILRDRARSFANL--VIERFHVKTPNAEKAAGSLSGGNLQKFIMGREILNRPRVLLVHQPTWGVD 425
Cdd:cd03224    93 EEN--------LLLGAYARRRAKRKARLerVYELFPRLKERRKQLAGTLSGGEQQMLAIARALMSRPKLLLLDEPSEGLA 164

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 2549828669 426 VGAAAVIRNSLIRLRDDGAAIIVVSEEIDELFEISDRIAVMYRG 469
Cdd:cd03224   165 PKIVEEIFEAIRELRDEGVTILLVEQNARFALEIADRAYVLERG 208

YddA

COG4178

ABC-type uncharacterized transport system, permease and ATPase components [General function ...

3-212

1.70e-15

ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only];

Pssm-ID: 443337 [Multi-domain] Cd Length: 571 Bit Score: 79.08 E-value: 1.70e-15

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   3 PRLSLRNITKRYP-GITANDHVSLDIAPGEVLAILGENGAGKSTLMKII-----YGaarpdEGEISFdghplgvetPAQA 76
Cdd:COG4178   361 GALALEDLTLRTPdGRPLLEDLSLSLKPGERLLITGPSGSGKSTLLRAIaglwpYG-----SGRIAR---------PAGA 426

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  77 RelgiamvhqhfALF---------DTLsvTENVAL-GLSTGISAAEIE---REIRL--LGEKYGLEVDPASVvmeLSMGE 141
Cdd:COG4178   427 R-----------VLFlpqrpylplGTL--REALLYpATAEAFSDAELRealEAVGLghLAERLDEEADWDQV---LSLGE 490

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2549828669 142 RQRVEILRALMTKPKLLILDEPTSVLTPQAVRKLFKTLHQlSSEGVSILFISHKlDEIRELADRCVVLRAG 212
Cdd:COG4178   491 QQRLAFARLLLHKPDWLFLDEATSALDEENEAALYQLLRE-ELPGTTVISVGHR-STLAAFHDRVLELTGD 559

ABC_Mj1267_LivG_branched

cd03219

ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ...

268-471

5.83e-15

Pssm-ID: 213186 [Multi-domain] Cd Length: 236 Bit Score: 74.40 E-value: 5.83e-15

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 268 IDNVSLAVRAGEIVGIAGISGNGQARFMAAASGEYLCEADRVLLFNSPVGELDTHARRisglryvpeqRLG------HAA 341
Cdd:cd03219    16 LDDVSFSVRPGEIHGLIGPNGAGKTTLFNLISGFLRPTSGSVLFDGEDITGLPPHEIA----------RLGigrtfqIPR 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 342 V-PELSLTANTYLTGDSLVRSGFILRDRARSFANL------VIERFHVkTPNAEKAAGSLSGGNLQKFIMGREILNRPRV 414
Cdd:cd03219    86 LfPELTVLENVMVAAQARTGSGLLLARARREEREAreraeeLLERVGL-ADLADRPAGELSYGQQRRLEIARALATDPKL 164

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2549828669 415 LLVHQPTWGVDVGAAAVIRNSLIRLRDDGAAIIVVSEEIDELFEISDRIAVMYRGAL 471
Cdd:cd03219   165 LLLDEPAAGLNPEETEELAELIRELRERGITVLLVEHDMDVVMSLADRVTVLDQGRV 221

3a01204

TIGR00955

The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ...

23-215

8.11e-15

The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]

Pssm-ID: 273361 [Multi-domain] Cd Length: 617 Bit Score: 77.01 E-value: 8.11e-15

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  23 VSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPD---EGEISFDGHPLGVEtpaQARELGiAMVHQHFALFDTLSVTE- 98
Cdd:TIGR00955  44 VSGVAKPGELLAVMGSSGAGKTTLMNALAFRSPKGvkgSGSVLLNGMPIDAK---EMRAIS-AYVQQDDLFIPTLTVREh 119

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  99 -NVALGLSTGISAAEIEREIRL--LGEKYGLE------VDPASVVMELSMGERQRVEILRALMTKPKLLILDEPTSVLTP 169
Cdd:TIGR00955 120 lMFQAHLRMPRRVTKKEKRERVdeVLQALGLRkcantrIGVPGRVKGLSGGERKRLAFASELLTDPPLLFCDEPTSGLDS 199

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 2549828669 170 QAVRKLFKTLHQLSSEGVSILFISHK-LDEIRELADRCVVLRAGKVV 215
Cdd:TIGR00955 200 FMAYSVVQVLKGLAQKGKTIICTIHQpSSELFELFDKIILMAEGRVA 246

PRK10253

iron-enterobactin ABC transporter ATP-binding protein;

2-237

1.17e-14

iron-enterobactin ABC transporter ATP-binding protein;

Pssm-ID: 182336 [Multi-domain] Cd Length: 265 Bit Score: 73.87 E-value: 1.17e-14

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   2 TPRLSLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDG-HPLGVETPAQARELG 80
Cdd:PRK10253    5 VARLRGEQLTLGYGKYTVAENLTVEIPDGHFTAIIGPNGCGKSTLLRTLSRLMTPAHGHVWLDGeHIQHYASKEVARRIG 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  81 iaMVHQHFALFDTLSVTENVALG------LSTGISaAEIEREIRLLGEKYGLEVDPASVVMELSMGERQRVEILRALMTK 154
Cdd:PRK10253   85 --LLAQNATTPGDITVQELVARGryphqpLFTRWR-KEDEEAVTKAMQATGITHLADQSVDTLSGGQRQRAWIAMVLAQE 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 155 PKLLILDEPTSVLTPQAVRKLFKTLHQLSSE-GVSILFISHKLDEIRELADRCVVLRAGKVVASVDPK----AESEENL- 228
Cdd:PRK10253  162 TAIMLLDEPTTWLDISHQIDLLELLSELNREkGYTLAAVLHDLNQACRYASHLIALREGKIVAQGAPKeivtAELIERIy 241

                         250
                  ....*....|
gi 2549828669 229 -ARLMIGNDP 237
Cdd:PRK10253  242 gLRCMIIDDP 251

hmuV

PRK13547

heme ABC transporter ATP-binding protein;

21-221

1.32e-14

heme ABC transporter ATP-binding protein;

Pssm-ID: 184132 [Multi-domain] Cd Length: 272 Bit Score: 74.09 E-value: 1.32e-14

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  21 DHVSLDIAPGEVLAILGENGAGKSTLMKIIYG----AARPD----EGEISFDGHPLGVETPAQARELGIAMVHQHFALFd 92
Cdd:PRK13547   18 RDLSLRIEPGRVTALLGRNGAGKSTLLKALAGdltgGGAPRgarvTGDVTLNGEPLAAIDAPRLARLRAVLPQAAQPAF- 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  93 TLSVTENVALG-LSTGISAAEIEREIRLLG----EKYGLEVDPASVVMELSMGERQRVEILRAL---------MTKPKLL 158
Cdd:PRK13547   97 AFSAREIVLLGrYPHARRAGALTHRDGEIAwqalALAGATALVGRDVTTLSGGELARVQFARVLaqlwpphdaAQPPRYL 176

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2549828669 159 ILDEPTSVLTPQAVRKLFKTLHQLSSE-GVSILFISHKLDEIRELADRCVVLRAGKVVASVDPK 221
Cdd:PRK13547  177 LLDEPTAALDLAHQHRLLDTVRRLARDwNLGVLAIVHDPNLAARHADRIAMLADGAIVAHGAPA 240

PRK10938

putative molybdenum transport ATP-binding protein ModF; Provisional

24-291

1.92e-14

putative molybdenum transport ATP-binding protein ModF; Provisional

Pssm-ID: 182852 [Multi-domain] Cd Length: 490 Bit Score: 75.44 E-value: 1.92e-14

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  24 SLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEI--SFDgHP--LGVETPAQarelgiaMVHQHFALFDT--LSVT 97
Cdd:PRK10938   23 SLTLNAGDSWAFVGANGSGKSALARALAGELPLLSGERqsQFS-HItrLSFEQLQK-------LVSDEWQRNNTdmLSPG 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  98 ENvalglSTGISAAE-IEREIR------LLGEKYGLEVDPASVVMELSMGERQRVEILRALMTKPKLLILDEPTSVLTPQ 170
Cdd:PRK10938   95 ED-----DTGRTTAEiIQDEVKdparceQLAQQFGITALLDRRFKYLSTGETRKTLLCQALMSEPDLLILDEPFDGLDVA 169

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 171 AVRKLFKTLHQLSSEGVSILFISHKLDEIRELADR------CVVLRAGK--------VVASVdpkAESEENLARLMIGND 236
Cdd:PRK10938  170 SRQQLAELLASLHQSGITLVLVLNRFDEIPDFVQFagvladCTLAETGEreeilqqaLVAQL---AHSEQLEGVQLPEPD 246

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2549828669 237 PPTVREgTAKAGEVVFEMRHVSAPGSTRVCgIDNVSLAVRAGEIVGIAGISGNGQ 291
Cdd:PRK10938  247 EPSARH-ALPANEPRIVLNNGVVSYNDRPI-LHNLSWQVNPGEHWQIVGPNGAGK 299

ABC_ABC_ChvD

TIGR03719

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ...

6-290

2.28e-14

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.

Pssm-ID: 274744 [Multi-domain] Cd Length: 552 Bit Score: 75.36 E-value: 2.28e-14

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   6 SLRNITKRYPG---ITANdhVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEIsfdghplgveTPAQARELGia 82
Cdd:TIGR03719   6 TMNRVSKVVPPkkeILKD--ISLSFFPGAKIGVLGLNGAGKSTLLRIMAGVDKDFNGEA----------RPQPGIKVG-- 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  83 MVHQHFALFDTLSVTENVALGLS---------TGISA--AEIEREIRLLGEKYG-----------------LEV------ 128
Cdd:TIGR03719  72 YLPQEPQLDPTKTVRENVEEGVAeikdaldrfNEISAkyAEPDADFDKLAAEQAelqeiidaadawdldsqLEIamdalr 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 129 --DPASVVMELSMGERQRVEILRALMTKPKLLILDEPTSVLTPQAVRKLFKTLHQLSSegvSILFISH------------ 194
Cdd:TIGR03719 152 cpPWDADVTKLSGGERRRVALCRLLLSKPDMLLLDEPTNHLDAESVAWLERHLQEYPG---TVVAVTHdryfldnvagwi 228

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 195 -KLD------------------------EIRELADRCVVLRAGKVVASVDPKAESEENLARL-----MIGNDPPTvREGT 244
Cdd:TIGR03719 229 lELDrgrgipwegnysswleqkqkrleqEEKEESARQKTLKRELEWVRQSPKGRQAKSKARLaryeeLLSQEFQK-RNET 307

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2549828669 245 A--------KAGEVVFEMRHVSAPGSTRVCgIDNVSLAVRAGEIVGIAGISGNG 290
Cdd:TIGR03719 308 AeiyippgpRLGDKVIEAENLTKAFGDKLL-IDDLSFKLPPGGIVGVIGPNGAG 360

ABC_NikE_OppD_transporters

cd03257

ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ...

268-471

3.58e-14

Pssm-ID: 213224 [Multi-domain] Cd Length: 228 Bit Score: 71.77 E-value: 3.58e-14

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 268 IDNVSLAVRAGEIVGIAGISGNGQ-------ARFMAAASGEylceadrVLLFNSPVGELDTHARRISGLR--YVPEQrlg 338
Cdd:cd03257    21 LDDVSFSIKKGETLGLVGESGSGKstlaraiLGLLKPTSGS-------IIFDGKDLLKLSRRLRKIRRKEiqMVFQD--- 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 339 haavPELSLtaNTYLT-GDSLVRSGFILR-DRARSFANLVIERFHVKTPNAEKAAGS----LSGGNLQKFIMGREILNRP 412
Cdd:cd03257    91 ----PMSSL--NPRMTiGEQIAEPLRIHGkLSKKEARKEAVLLLLVGVGLPEEVLNRypheLSGGQRQRVAIARALALNP 164

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 413 RVLLVHQPTWGVDVGAAAVIRNSLIRLRDD-GAAIIVVSEEIDELFEISDRIAVMYRGAL 471
Cdd:cd03257   165 KLLIADEPTSALDVSVQAQILDLLKKLQEElGLTLLFITHDLGVVAKIADRVAVMYAGKI 224

xylG

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ...

251-499

3.64e-14

Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 74.86 E-value: 3.64e-14

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 251 VFEMRHVSAPGSTrVCGIDNVSLAVRAGEIVGIAGISGNGQARFMAAASGEYLC-EADRVLLFN-SPV---GELDTHARR 325
Cdd:TIGR02633   1 LLEMKGIVKTFGG-VKALDGIDLEVRPGECVGLCGENGAGKSTLMKILSGVYPHgTWDGEIYWSgSPLkasNIRDTERAG 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 326 ISglryVPEQRLghAAVPELSLTANTYLtGDSLVRSGFILRDRARSF-ANLVIERFHVKTPNAEKAAGSLSGGNLQKFIM 404
Cdd:TIGR02633  80 IV----IIHQEL--TLVPELSVAENIFL-GNEITLPGGRMAYNAMYLrAKNLLRELQLDADNVTRPVGDYGGGQQQLVEI 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 405 GREILNRPRVLLVHQPTWGVDVGAAAVIRNSLIRLRDDGAAIIVVSEEIDELFEISDRIAVMYRGALSPAVPKPTISIEE 484
Cdd:TIGR02633 153 AKALNKQARLLILDEPSSSLTEKETEILLDIIRDLKAHGVACVYISHKLNEVKAVCDTICVIRDGQHVATKDMSTMSEDD 232

                         250       260
                  ....*....|....*....|
gi 2549828669 485 -----VGRWMSGLWPDSPFT 499
Cdd:TIGR02633 233 iitmmVGREITSLYPHEPHE 252

ABCG_PDR_domain1

cd03233

First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette ...

5-215

4.30e-14

First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.

Pssm-ID: 213200 [Multi-domain] Cd Length: 202 Bit Score: 71.14 E-value: 4.30e-14

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   5 LSLRNIT----KRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPD---EGEISFDGHPLGVETPAQAR 77
Cdd:cd03233     4 LSWRNISfttgKGRSKIPILKDFSGVVKPGEMVLVLGRPGSGCSTLLKALANRTEGNvsvEGDIHYNGIPYKEFAEKYPG 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  78 ElgIAMVHQHFALFDTLSVTENvalglstgisaaeIEREIRLLGEKYglevdpasvVMELSMGERQRVEILRALMTKPKL 157
Cdd:cd03233    84 E--IIYVSEEDVHFPTLTVRET-------------LDFALRCKGNEF---------VRGISGGERKRVSIAEALVSRASV 139

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 158 LILDEPTSVLTPQAVRKLFKTLHQLS--SEGVSILFISHKLDEIRELADRCVVLRAGKVV 215
Cdd:cd03233   140 LCWDNSTRGLDSSTALEILKCIRTMAdvLKTTTFVSLYQASDEIYDLFDKVLVLYEGRQI 199

ABC_putative_ATPase

cd03269

ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ...

264-469

8.16e-14

Pssm-ID: 213236 [Multi-domain] Cd Length: 210 Bit Score: 70.39 E-value: 8.16e-14

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 264 RVCGIDNVSLAVRAGEIVGIAGISGNGQARFMAAASGEYLCEADRVLLFNSPVGELDTHArrisgLRYVPEQRlghAAVP 343
Cdd:cd03269    12 RVTALDDISFSVEKGEIFGLLGPNGAGKTTTIRMILGIILPDSGEVLFDGKPLDIAARNR-----IGYLPEER---GLYP 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 344 ELSLTAN-TYLTgdSLvrSGFILRDrARSFANLVIERFHVkTPNAEKAAGSLSGGNLQKFIMGREILNRPRVLLVHQPTW 422
Cdd:cd03269    84 KMKVIDQlVYLA--QL--KGLKKEE-ARRRIDEWLERLEL-SEYANKRVEELSKGNQQKVQFIAAVIHDPELLILDEPFS 157

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 2549828669 423 GVDVGAAAVIRNSLIRLRDDGAAIIVVSEEIDELFEISDRIAVMYRG 469
Cdd:cd03269   158 GLDPVNVELLKDVIRELARAGKTVILSTHQMELVEELCDRVLLLNKG 204

PLN03232

ABC transporter C family member; Provisional

13-230

2.79e-13

ABC transporter C family member; Provisional

Pssm-ID: 215640 [Multi-domain] Cd Length: 1495 Bit Score: 72.70 E-value: 2.79e-13

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   13 RY-PGITANDH-VSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQARELgIAMVHQHFAL 90
Cdd:PLN03232  1243 RYrPGLPPVLHgLSFFVSPSEKVGVVGRTGAGKSSMLNALFRIVELEKGRIMIDDCDVAKFGLTDLRRV-LSIIPQSPVL 1321

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   91 F--------DTLSvtENVALGLSTGISAAEIEREIRllGEKYGLEVDPASVVMELSMGERQRVEILRALMTKPKLLILDE 162
Cdd:PLN03232  1322 FsgtvrfniDPFS--EHNDADLWEALERAHIKDVID--RNPFGLDAEVSEGGENFSVGQRQLLSLARALLRRSKILVLDE 1397

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2549828669  163 PTS-------VLTPQAVRKLFKTlhqlssegVSILFISHKLDEIRElADRCVVLRAGKVVASVDPkaesEENLAR 230
Cdd:PLN03232  1398 ATAsvdvrtdSLIQRTIREEFKS--------CTMLVIAHRLNTIID-CDKILVLSSGQVLEYDSP----QELLSR 1459

ABCD_peroxisomal_ALDP

cd03223

ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding ...

21-194

2.81e-13

ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding cassette transporter (Pat) is involved in the import of very long-chain fatty acids (VLCFA) into the peroxisome. The peroxisomal membrane forms a permeability barrier for a wide variety of metabolites required for and formed during fatty acid beta-oxidation. To communicate with the cytoplasm and mitochondria, peroxisomes need dedicated proteins to transport such hydrophilic molecules across their membranes. X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ALD gene, which encodes ALDP (adrenoleukodystrophy protein ), a peroxisomal integral membrane protein that is a member of the ATP-binding cassette (ABC) transporter protein family. The disease is characterized by a striking and unpredictable variation in phenotypic expression. Phenotypes include the rapidly progressive childhood cerebral form (CCALD), the milder adult form, adrenomyeloneuropathy (AMN), and variants without neurologic involvement (i.e. asymptomatic).

Pssm-ID: 213190 [Multi-domain] Cd Length: 166 Bit Score: 67.56 E-value: 2.81e-13

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  21 DHVSLDIAPGEVLAILGENGAGKSTLMKIIygaarpdeGEI--SFDGHplgVETPAQArelGIAMVHQHfALFDTLSVTE 98
Cdd:cd03223    18 KDLSFEIKPGDRLLITGPSGTGKSSLFRAL--------AGLwpWGSGR---IGMPEGE---DLLFLPQR-PYLPLGTLRE 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  99 NVALGLStgisaaeiereirllgekyglevdpasvvMELSMGERQRVEILRALMTKPKLLILDEPTSVLTPQAVRKLFKT 178
Cdd:cd03223    83 QLIYPWD-----------------------------DVLSGGEQQRLAFARLLLHKPKFVFLDEATSALDEESEDRLYQL 133

                         170
                  ....*....|....*.
gi 2549828669 179 LHQlssEGVSILFISH 194
Cdd:cd03223   134 LKE---LGITVISVGH 146

PRK10982

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional

5-231

2.93e-13

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional

Pssm-ID: 182880 [Multi-domain] Cd Length: 491 Bit Score: 71.68 E-value: 2.93e-13

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   5 LSLRNIT-KRYPGItanDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQARELGiam 83
Cdd:PRK10982  251 LEVRNLTsLRQPSI---RDVSFDLHKGEILGIAGLVGAKRTDIVETLFGIREKSAGTITLHGKKINNHNANEAINHG--- 324

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  84 vhqhFALfdtlsVTENVAlglSTGISAA-EIE-----REIRLLGEKYGL------------EVDPASV--------VMEL 137
Cdd:PRK10982  325 ----FAL-----VTEERR---STGIYAYlDIGfnsliSNIRNYKNKVGLldnsrmksdtqwVIDSMRVktpghrtqIGSL 392

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 138 SMGERQRVEILRALMTKPKLLILDEPTSVLTPQAVRKLFKTLHQLSSEGVSILFISHKLDEIRELADRCVVLRAGKVVAS 217
Cdd:PRK10982  393 SGGNQQKVIIGRWLLTQPEILMLDEPTRGIDVGAKFEIYQLIAELAKKDKGIIIISSEMPELLGITDRILVMSNGLVAGI 472

                         250
                  ....*....|....
gi 2549828669 218 VDPKAESEENLARL 231
Cdd:PRK10982  473 VDTKTTTQNEILRL 486

ABC_ABC_ChvD

TIGR03719

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ...

3-199

3.15e-13

Pssm-ID: 274744 [Multi-domain] Cd Length: 552 Bit Score: 71.89 E-value: 3.15e-13

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   3 PRL-----SLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDghplgvETpaqar 77
Cdd:TIGR03719 316 PRLgdkviEAENLTKAFGDKLLIDDLSFKLPPGGIVGVIGPNGAGKSTLFRMITGQEQPDSGTIEIG------ET----- 384

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  78 eLGIAMVHQ-HFALFDTLSVTENVALGLstgisaaeierEIRLLGekyGLEV--------------DPASVVMELSMGER 142
Cdd:TIGR03719 385 -VKLAYVDQsRDALDPNKTVWEEISGGL-----------DIIKLG---KREIpsrayvgrfnfkgsDQQKKVGQLSGGER 449

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 143 QRVEILRALMTKPKLLILDEPTSVLTPQAVRKLFKTLhqLSSEGVSILfISHK---LDEI 199
Cdd:TIGR03719 450 NRVHLAKTLKSGGNVLLLDEPTNDLDVETLRALEEAL--LNFAGCAVV-ISHDrwfLDRI 506

ABC_NatA_sodium_exporter

cd03266

ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ...

262-471

3.71e-13

Pssm-ID: 213233 [Multi-domain] Cd Length: 218 Bit Score: 68.55 E-value: 3.71e-13

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 262 STRVCGIDNVSLAVRAGEIVGIAGISGNGQARFMAAASGeyLCEADRvllFNSPVGELDTH-----ARRisGLRYVPEQR 336
Cdd:cd03266    15 KKTVQAVDGVSFTVKPGEVTGLLGPNGAGKTTTLRMLAG--LLEPDA---GFATVDGFDVVkepaeARR--RLGFVSDST 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 337 lghAAVPELSLTANTYLTGDSLVRSGFILRDRArsfaNLVIERFHVKtPNAEKAAGSLSGGNLQKFIMGREILNRPRVLL 416
Cdd:cd03266    88 ---GLYDRLTARENLEYFAGLYGLKGDELTARL----EELADRLGME-ELLDRRVGGFSTGMRQKVAIARALVHDPPVLL 159

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2549828669 417 VHQPTWGVDVGAAAVIRNSLIRLRDDGAAIIVVSEEIDELFEISDRIAVMYRGAL 471
Cdd:cd03266   160 LDEPTTGLDVMATRALREFIRQLRALGKCILFSTHIMQEVERLCDRVVVLHRGRV 214

PRK13549

xylose transporter ATP-binding subunit; Provisional

249-497

3.91e-13

xylose transporter ATP-binding subunit; Provisional

Pssm-ID: 184134 [Multi-domain] Cd Length: 506 Bit Score: 71.50 E-value: 3.91e-13

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 249 EVVFEMRHV--SAPGstrVCGIDNVSLAVRAGEIVGIAGISGNGQARFMAAASGEYLC---EADrvLLFNspvGEL---- 319
Cdd:PRK13549    3 EYLLEMKNItkTFGG---VKALDNVSLKVRAGEIVSLCGENGAGKSTLMKVLSGVYPHgtyEGE--IIFE---GEElqas 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 320 ---DTHARRISglryVPEQRLghAAVPELSLTANTYLtGDSLVRSGFILRDRARSFANLVIERFHVKTPNAEKAaGSLSG 396
Cdd:PRK13549   75 nirDTERAGIA----IIHQEL--ALVKELSVLENIFL-GNEITPGGIMDYDAMYLRAQKLLAQLKLDINPATPV-GNLGL 146

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 397 GNLQKFIMGREILNRPRVLLVHQPTWGVDVGAAAVIRNSLIRLRDDGAAIIVVSEEIDELFEISDRIAVMYRGALSPAVP 476
Cdd:PRK13549  147 GQQQLVEIAKALNKQARLLILDEPTASLTESETAVLLDIIRDLKAHGIACIYISHKLNEVKAISDTICVIRDGRHIGTRP 226

                         250       260
                  ....*....|....*....|....*.
gi 2549828669 477 KPTISIEE-----VGRWMSGLWPDSP 497
Cdd:PRK13549  227 AAGMTEDDiitmmVGRELTALYPREP 252

3a01205

TIGR00956

Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]

21-215

4.06e-13

Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]

Pssm-ID: 273362 [Multi-domain] Cd Length: 1394 Bit Score: 72.06 E-value: 4.06e-13

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   21 DHVSLDIAPGEVLAILGENGAGKSTLMKIIygAARPDEGEISFD-----GHPLgvETPAQARelgIAMVHQHFALFDTLS 95
Cdd:TIGR00956  780 NNVDGWVKPGTLTALMGASGAGKTTLLNVL--AERVTTGVITGGdrlvnGRPL--DSSFQRS---IGYVQQQDLHLPTST 852

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   96 VTENV----ALGLSTGISAAE----IEREIRLLG-EKYGLEVdpASVVME-LSMGERQRVEILRALMTKPKLLI-LDEPT 164
Cdd:TIGR00956  853 VRESLrfsaYLRQPKSVSKSEkmeyVEEVIKLLEmESYADAV--VGVPGEgLNVEQRKRLTIGVELVAKPKLLLfLDEPT 930

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|...
gi 2549828669  165 SVLTPQAVRKLFKTLHQLSSEGVSILFISHKLD-EIRELADRCVVL-RAGKVV 215
Cdd:TIGR00956  931 SGLDSQTAWSICKLMRKLADHGQAILCTIHQPSaILFEEFDRLLLLqKGGQTV 983

ABC_ATPase

cd00267

ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ...

268-469

4.33e-13

Pssm-ID: 213179 [Multi-domain] Cd Length: 157 Bit Score: 66.88 E-value: 4.33e-13

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 268 IDNVSLAVRAGEIVGIAGISGNGQARFMAAASGEYLCEADRVLLFNSPVGELDTHARRiSGLRYVPEqrlghaavpelsl 347
Cdd:cd00267    15 LDNVSLTLKAGEIVALVGPNGSGKSTLLRAIAGLLKPTSGEILIDGKDIAKLPLEELR-RRIGYVPQ------------- 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 348 tantyltgdslvrsgfilrdrarsfanlvierfhvktpnaekaagsLSGGNLQKFIMGREILNRPRVLLVHQPTWGVDVG 427
Cdd:cd00267    81 ----------------------------------------------LSGGQRQRVALARALLLNPDLLLLDEPTSGLDPA 114

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 2549828669 428 AAAVIRNSLIRLRDDGAAIIVVSEEIDELFEISDRIAVMYRG 469
Cdd:cd00267   115 SRERLLELLRELAEEGRTVIIVTHDPELAELAADRVIVLKDG 156

PLN03211

ABC transporter G-25; Provisional

27-213

4.47e-13

ABC transporter G-25; Provisional

Pssm-ID: 215634 [Multi-domain] Cd Length: 659 Bit Score: 71.83 E-value: 4.47e-13

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  27 IAPGEVLAILGENGAGKSTLMKIIYGAARPDegeiSFDGHPLGVE-TPAQARELGIAMVHQHFALFDTLSVTENVA---- 101
Cdd:PLN03211   91 ASPGEILAVLGPSGSGKSTLLNALAGRIQGN----NFTGTILANNrKPTKQILKRTGFVTQDDILYPHLTVRETLVfcsl 166

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 102 LGLSTGISAAE----IEREIRLLG-EKYGLEVDPASVVMELSMGERQRVEILRALMTKPKLLILDEPTSVLTPQAVRKLF 176
Cdd:PLN03211  167 LRLPKSLTKQEkilvAESVISELGlTKCENTIIGNSFIRGISGGERKRVSIAHEMLINPSLLILDEPTSGLDATAAYRLV 246

                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 2549828669 177 KTLHQLSSEGVSILFISHK-LDEIRELADRCVVLRAGK 213
Cdd:PLN03211  247 LTLGSLAQKGKTIVTSMHQpSSRVYQMFDSVLVLSEGR 284

ABC_Carb_Solutes_like

cd03259

ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ...

261-469

4.97e-13

Pssm-ID: 213226 [Multi-domain] Cd Length: 213 Bit Score: 68.31 E-value: 4.97e-13

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 261 GSTRVcgIDNVSLAVRAGEIVGIAGISGNGQ-------ARFMAAASGEylceadrVLLFNSPVGELDTHARRISglrYVP 333
Cdd:cd03259    11 GSVRA--LDDLSLTVEPGEFLALLGPSGCGKttllrliAGLERPDSGE-------ILIDGRDVTGVPPERRNIG---MVF 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 334 EQrlgHAAVPELSLTANTyltgdslvrsGFILRDRARSFAN------LVIERFHVkTPNAEKAAGSLSGGNLQKFIMGRE 407
Cdd:cd03259    79 QD---YALFPHLTVAENI----------AFGLKLRGVPKAEirarvrELLELVGL-EGLLNRYPHELSGGQQQRVALARA 144

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2549828669 408 ILNRPRVLLVHQPTWGVDVGAAAVIRNSLIRLRDD-GAAIIVVSEEIDELFEISDRIAVMYRG 469
Cdd:cd03259   145 LAREPSLLLLDEPLSALDAKLREELREELKELQRElGITTIYVTHDQEEALALADRIAVMNEG 207

PRK14243

phosphate transporter ATP-binding protein; Provisional

5-204

6.00e-13

phosphate transporter ATP-binding protein; Provisional

Pssm-ID: 184588 [Multi-domain] Cd Length: 264 Bit Score: 69.04 E-value: 6.00e-13

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   5 LSLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMK-------IIYGAARpdEGEISFDGHPL---GVEtPA 74
Cdd:PRK14243   11 LRTENLNVYYGSFLAVKNVWLDIPKNQITAFIGPSGCGKSTILRcfnrlndLIPGFRV--EGKVTFHGKNLyapDVD-PV 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  75 QARELgIAMVHQHFALFDTlSVTENVALGLST----GISAAEIEREIR---LLGE-KYGLEVDPASvvmeLSMGERQRVE 146
Cdd:PRK14243   88 EVRRR-IGMVFQKPNPFPK-SIYDNIAYGARIngykGDMDELVERSLRqaaLWDEvKDKLKQSGLS----LSGGQQQRLC 161

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2549828669 147 ILRALMTKPKLLILDEPTSVLTPQAVRKLFKTLHQLsSEGVSILFISHKLDEIRELAD 204
Cdd:PRK14243  162 IARAIAVQPEVILMDEPCSALDPISTLRIEELMHEL-KEQYTIIIVTHNMQQAARVSD 218

PRK10895

lipopolysaccharide ABC transporter ATP-binding protein; Provisional

268-487

1.02e-12

lipopolysaccharide ABC transporter ATP-binding protein; Provisional

Pssm-ID: 182817 [Multi-domain] Cd Length: 241 Bit Score: 68.00 E-value: 1.02e-12

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 268 IDNVSLAVRAGEIVGIAGISGNGQARFMAAASGEYLCEADRVLLFNSPVGELDTHARRISGLRYVPEQRlghAAVPELSL 347
Cdd:PRK10895   19 VEDVSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRDAGNIIIDDEDISLLPLHARARRGIGYLPQEA---SIFRRLSV 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 348 TANtyLTGDSLVRSGFILRDRARSfANLVIERFHVKTPNaEKAAGSLSGGNLQKFIMGREILNRPRVLLVHQPTWGVDVG 427
Cdd:PRK10895   96 YDN--LMAVLQIRDDLSAEQREDR-ANELMEEFHIEHLR-DSMGQSLSGGERRRVEIARALAANPKFILLDEPFAGVDPI 171

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2549828669 428 AAAVIRNSLIRLRDDGAAIIVVSEEIDELFEISDRIAVMYRGAL-SPAVPKPTISIEEVGR 487
Cdd:PRK10895  172 SVIDIKRIIEHLRDSGLGVLITDHNVRETLAVCERAYIVSQGHLiAHGTPTEILQDEHVKR 232

40850658_otr

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;

5-216

1.08e-12

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;

Pssm-ID: 411078 [Multi-domain] Cd Length: 351 Bit Score: 69.38 E-value: 1.08e-12

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   5 LSLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAG--KSTLMKIIYGaarPDEGEISFDGHPLGVETPAQARELGIa 82
Cdd:NF000106   14 VEVRGLVKHFGEVKAVDGVDLDVREGTVLGVLGP*GAA**RGALPAHV*G---PDAGRRPWRF*TWCANRRALRRTIG*- 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  83 mvHQ--HFALFDTLSVTENV-ALGLSTGISAAEIEREIRLLGEKYGLEVDPASVVMELSMGERQRVEILRALMTKPKLLI 159
Cdd:NF000106   90 --HRpvR*GRRESFSGRENLyMIGR*LDLSRKDARARADELLERFSLTEAAGRAAAKYSGGMRRRLDLAASMIGRPAVLY 167

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2549828669 160 LDEPTSVLTPQAVRKLFKTLHQLSSEGVSILFISHKLDEIRELADRCVVLRAGKVVA 216
Cdd:NF000106  168 LDEPTTGLDPRTRNEVWDEVRSMVRDGATVLLTTQYMEEAEQLAHELTVIDRGRVIA 224

ABC_Org_Solvent_Resistant

cd03261

ATP-binding cassette transport system involved in resistance to organic solvents; ABC ...

253-469

1.22e-12

Pssm-ID: 213228 [Multi-domain] Cd Length: 235 Bit Score: 67.53 E-value: 1.22e-12

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 253 EMRHVS-APGSTRVcgIDNVSLAVRAGEIVGIAGISGNGQARFMAAASGEYLCEADRVLLFNSPVGELDTHARRisGLRy 331
Cdd:cd03261     2 ELRGLTkSFGGRTV--LKGVDLDVRRGEILAIIGPSGSGKSTLLRLIVGLLRPDSGEVLIDGEDISGLSEAELY--RLR- 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 332 vpeQRLG----HAAvpeL--SLTantylTGDSLvrsGFILRDRARSFANLVIERFHVK------TPNAEKAAGSLSGGNL 399
Cdd:cd03261    77 ---RRMGmlfqSGA---LfdSLT-----VFENV---AFPLREHTRLSEEEIREIVLEKleavglRGAEDLYPAELSGGMK 142

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2549828669 400 QKFIMGREILNRPRVLLVHQPTWGVDVGAAAVIRNSLIRLRDD-GAAIIVVSEEIDELFEISDRIAVMYRG 469
Cdd:cd03261   143 KRVALARALALDPELLLYDEPTAGLDPIASGVIDDLIRSLKKElGLTSIMVTHDLDTAFAIADRIAVLYDG 213

Rli1

COG1245

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...

9-208

1.64e-12

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];

Pssm-ID: 440858 [Multi-domain] Cd Length: 592 Bit Score: 69.81 E-value: 1.64e-12

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   9 NITKRYPGItandhvSLDIAPG-----EVLAILGENGAGKSTLMKIIYGAARPDEGE------ISFDGHPLGVETPAQAR 77
Cdd:COG1245   346 DLTKSYGGF------SLEVEGGeiregEVLGIVGPNGIGKTTFAKILAGVLKPDEGEvdedlkISYKPQYISPDYDGTVE 419

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  78 ELgiamvhqhfaLFDTLSVTenvalgLSTGISAAEIEREIRL--LGEKYglevdpasvVMELSMGERQRVEILRALMTKP 155
Cdd:COG1245   420 EF----------LRSANTDD------FGSSYYKTEIIKPLGLekLLDKN---------VKDLSGGELQRVAIAACLSRDA 474

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 156 KLLILDEPTS-------VLTPQAVRKLFKtlhqlsSEGVSILFISHKLDEIRELADRCVV 208
Cdd:COG1245   475 DLYLLDEPSAhldveqrLAVAKAIRRFAE------NRGKTAMVVDHDIYLIDYISDRLMV 528

tagH

PRK13545

teichoic acids export protein ATP-binding subunit; Provisional

19-214

4.30e-12

teichoic acids export protein ATP-binding subunit; Provisional

Pssm-ID: 184130 [Multi-domain] Cd Length: 549 Bit Score: 68.38 E-value: 4.30e-12

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  19 ANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGhplgvetpaqarelGIAMVHQHFALFDTLSVTE 98
Cdd:PRK13545   39 ALNNISFEVPEGEIVGIIGLNGSGKSTLSNLIAGVTMPNKGTVDIKG--------------SAALIAISSGLNGQLTGIE 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  99 NVAL-GLSTGISAAEIEREIRLLGEKYGLEVDPASVVMELSMGERQRVEILRALMTKPKLLILDEPTSVLTPQAVRKLFK 177
Cdd:PRK13545  105 NIELkGLMMGLTKEKIKEIIPEIIEFADIGKFIYQPVKTYSSGMKSRLGFAISVHINPDILVIDEALSVGDQTFTKKCLD 184

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 2549828669 178 TLHQLSSEGVSILFISHKLDEIRELADRCVVLRAGKV 214
Cdd:PRK13545  185 KMNEFKEQGKTIFFISHSLSQVKSFCTKALWLHYGQV 221

PRK15064

ABC transporter ATP-binding protein; Provisional

5-215

6.41e-12

ABC transporter ATP-binding protein; Provisional

Pssm-ID: 237894 [Multi-domain] Cd Length: 530 Bit Score: 67.61 E-value: 6.41e-12

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   5 LSLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFdghplgvetpAQARELGIaMV 84
Cdd:PRK15064  320 LEVENLTKGFDNGPLFKNLNLLLEAGERLAIIGENGVGKTTLLRTLVGELEPDSGTVKW----------SENANIGY-YA 388

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  85 HQHFALFDT-LSVTENVALGLSTGisaaEIEREIR-LLGEKYGLEVDPASVVMELSMGERQRVEILRALMTKPKLLILDE 162
Cdd:PRK15064  389 QDHAYDFENdLTLFDWMSQWRQEG----DDEQAVRgTLGRLLFSQDDIKKSVKVLSGGEKGRMLFGKLMMQKPNVLVMDE 464

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2549828669 163 PTSVLTPQAVRKLFKTLHQLssEGvSILFISHKLDEIRELADRCVVLRAGKVV 215
Cdd:PRK15064  465 PTNHMDMESIESLNMALEKY--EG-TLIFVSHDREFVSSLATRIIEITPDGVV 514

CFTR_protein

TIGR01271

cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ...

23-212

7.99e-12

cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]

Pssm-ID: 273530 [Multi-domain] Cd Length: 1490 Bit Score: 68.01 E-value: 7.99e-12

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   23 VSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHplgvetpaqarelgIAMVHQhFALFDTLSVTENVAL 102
Cdd:TIGR01271  445 ISFKLEKGQLLAVAGSTGSGKSSLLMMIMGELEPSEGKIKHSGR--------------ISFSPQ-TSWIMPGTIKDNIIF 509

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  103 GLS-------TGISAAEIEREIRLLGEKyglevdPASVVME----LSMGERQRVEILRALMTKPKLLILDEPTSVLTPQA 171
Cdd:TIGR01271  510 GLSydeyrytSVIKACQLEEDIALFPEK------DKTVLGEggitLSGGQRARISLARAVYKDADLYLLDSPFTHLDVVT 583

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|..
gi 2549828669  172 VRKLFKT-LHQLSSEGVSILFIShKLDEIRElADRCVVLRAG 212
Cdd:TIGR01271  584 EKEIFEScLCKLMSNKTRILVTS-KLEHLKK-ADKILLLHEG 623

ABC_Class3

cd03229

ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ...

268-469

9.63e-12

Pssm-ID: 213196 [Multi-domain] Cd Length: 178 Bit Score: 63.75 E-value: 9.63e-12

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 268 IDNVSLAVRAGEIVGIAGISGNGQARFMaaasgeylceadrvllfnspvgeldthaRRISGLryvpeqrlghaavpeLSL 347
Cdd:cd03229    16 LNDVSLNIEAGEIVALLGPSGSGKSTLL----------------------------RCIAGL---------------EEP 52

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 348 TANTYLTGDSLVRSGFILRDRARSFANLVIERFHVkTPN---AEKAAGSLSGGNLQKFIMGREILNRPRVLLVHQPTWGV 424
Cdd:cd03229    53 DSGSILIDGEDLTDLEDELPPLRRRIGMVFQDFAL-FPHltvLENIALGLSGGQQQRVALARALAMDPDVLLLDEPTSAL 131

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 2549828669 425 DVGAAAVIRNSLIRLRD-DGAAIIVVSEEIDELFEISDRIAVMYRG 469
Cdd:cd03229   132 DPITRREVRALLKSLQAqLGITVVLVTHDLDEAARLADRVVVLRDG 177

PRK13543

heme ABC exporter ATP-binding protein CcmA;

27-172

1.02e-11

heme ABC exporter ATP-binding protein CcmA;

Pssm-ID: 184129 [Multi-domain] Cd Length: 214 Bit Score: 64.48 E-value: 1.02e-11

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  27 IAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPlgVETPAQARElgIAMVHQHFALFDTLSVTENVALglst 106
Cdd:PRK13543   34 VDAGEALLVQGDNGAGKTTLLRVLAGLLHVESGQIQIDGKT--ATRGDRSRF--MAYLGHLPGLKADLSTLENLHF---- 105

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2549828669 107 gISAAEIEREIRLLGEKY---GLEVDPASVVMELSMGERQRVEILRALMTKPKLLILDEPTSVLTPQAV 172
Cdd:PRK13543  106 -LCGLHGRRAKQMPGSALaivGLAGYEDTLVRQLSAGQKKRLALARLWLSPAPLWLLDEPYANLDLEGI 173

PLN03130

ABC transporter C family member; Provisional

22-215

1.12e-11

ABC transporter C family member; Provisional

Pssm-ID: 215595 [Multi-domain] Cd Length: 1622 Bit Score: 67.84 E-value: 1.12e-11

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   22 HVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQARE-LGIamVHQHFALF--------D 92
Cdd:PLN03130  1257 GLSFEISPSEKVGIVGRTGAGKSSMLNALFRIVELERGRILIDGCDISKFGLMDLRKvLGI--IPQAPVLFsgtvrfnlD 1334

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   93 TLSvtENVALGLSTGISAAEIEREIRllGEKYGLEVDPASVVMELSMGERQRVEILRALMTKPKLLILDEPTS------- 165
Cdd:PLN03130  1335 PFN--EHNDADLWESLERAHLKDVIR--RNSLGLDAEVSEAGENFSVGQRQLLSLARALLRRSKILVLDEATAavdvrtd 1410

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|
gi 2549828669  166 VLTPQAVRKLFKTlhqlssegVSILFISHKLDEIRElADRCVVLRAGKVV 215
Cdd:PLN03130  1411 ALIQKTIREEFKS--------CTMLIIAHRLNTIID-CDRILVLDAGRVV 1451

sufC

PRK09580

cysteine desulfurase ATPase component; Reviewed

5-219

1.18e-11

cysteine desulfurase ATPase component; Reviewed

Pssm-ID: 181965 [Multi-domain] Cd Length: 248 Bit Score: 64.81 E-value: 1.18e-11

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   5 LSLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAA--RPDEGEISFDGHPLGVETPAQARELGIA 82
Cdd:PRK09580    2 LSIKDLHVSVEDKAILRGLNLEVRPGEVHAIMGPNGSGKSTLSATLAGREdyEVTGGTVEFKGKDLLELSPEDRAGEGIF 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  83 MVHQHFALFDTLSVTenvaLGLSTGISAAE----------------IEREIRLLgeKYGLEVDPASVVMELSMGERQRVE 146
Cdd:PRK09580   82 MAFQYPVEIPGVSNQ----FFLQTALNAVRsyrgqepldrfdfqdlMEEKIALL--KMPEDLLTRSVNVGFSGGEKKRND 155

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2549828669 147 ILRALMTKPKLLILDEPTSVLTPQAVRKLFKTLHQLSSEGVSILFISHK---LDEIRelADRCVVLRAGKVVASVD 219
Cdd:PRK09580  156 ILQMAVLEPELCILDESDSGLDIDALKIVADGVNSLRDGKRSFIIVTHYqriLDYIK--PDYVHVLYQGRIVKSGD 229

nikD

PRK10418

nickel transporter ATP-binding protein NikD; Provisional

1-215

1.37e-11

nickel transporter ATP-binding protein NikD; Provisional

Pssm-ID: 236688 [Multi-domain] Cd Length: 254 Bit Score: 64.72 E-value: 1.37e-11

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   1 MTPRLSLRNITKRYPGITAnDHVSLDIAPGEVLAILGENGAGKS----TLMKIIYGAARPDEGEISFDGHPLgveTPAQA 76
Cdd:PRK10418    1 MPQQIELRNIALQAAQPLV-HGVSLTLQRGRVLALVGGSGSGKSltcaAALGILPAGVRQTAGRVLLDGKPV---APCAL 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  77 RELGIAMVHQH----FALFDTLSvtenvALGLSTGISAAEIEREIRLLG--EKYGLEvDPASVV----MELSMGERQRVE 146
Cdd:PRK10418   77 RGRKIATIMQNprsaFNPLHTMH-----THARETCLALGKPADDATLTAalEAVGLE-NAARVLklypFEMSGGMLQRMM 150

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 147 ILRALMTKPKLLILDEPTSVLTPQAVRKLFKTLHQLSSE-GVSILFISHKLDEIRELADRCVVLRAGKVV 215
Cdd:PRK10418  151 IALALLCEAPFIIADEPTTDLDVVAQARILDLLESIVQKrALGMLLVTHDMGVVARLADDVAVMSHGRIV 220

PRK10636

putative ABC transporter ATP-binding protein; Provisional

2-214

1.74e-11

putative ABC transporter ATP-binding protein; Provisional

Pssm-ID: 236729 [Multi-domain] Cd Length: 638 Bit Score: 66.73 E-value: 1.74e-11

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   2 TPRLSLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFdghplgvetpAQARELGI 81
Cdd:PRK10636  310 NPLLKMEKVSAGYGDRIILDSIKLNLVPGSRIGLLGRNGAGKSTLIKLLAGELAPVSGEIGL----------AKGIKLGY 379

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  82 AMVHQhfalFDTLSVTENvALGLSTGISAAEIEREIRLLGEKYGLEVDPASVVME-LSMGERQRVEILRALMTKPKLLIL 160
Cdd:PRK10636  380 FAQHQ----LEFLRADES-PLQHLARLAPQELEQKLRDYLGGFGFQGDKVTEETRrFSGGEKARLVLALIVWQRPNLLLL 454

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2549828669 161 DEPTSVLTPQAVRKLFKTLhqLSSEGvSILFISHKLDEIRELADRCVVLRAGKV 214
Cdd:PRK10636  455 DEPTNHLDLDMRQALTEAL--IDFEG-ALVVVSHDRHLLRSTTDDLYLVHDGKV 505

GsiA

COG1123

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ...

256-471

2.41e-11

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];

Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 65.69 E-value: 2.41e-11

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 256 HVSAPGSTRVcGIDNVSLAVRAGEIVGIAGISGNGQ---ARFMAAASGEYLCEADRVLLFNSPVGELDTHAR--RISglr 330
Cdd:COG1123    11 SVRYPGGDVP-AVDGVSLTIAPGETVALVGESGSGKstlALALMGLLPHGGRISGEVLLDGRDLLELSEALRgrRIG--- 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 331 YVPEQrlghaavPELSLTANTylTGDSLV---RSGFILRDRARSFANLVIERFHVKTPnAEKAAGSLSGGNLQKFIMGRE 407
Cdd:COG1123    87 MVFQD-------PMTQLNPVT--VGDQIAealENLGLSRAEARARVLELLEAVGLERR-LDRYPHQLSGGQRQRVAIAMA 156

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2549828669 408 ILNRPRVLLVHQPTWGVDVGAAAVIRNSLIRL-RDDGAAIIVVSEEIDELFEISDRIAVMYRGAL 471
Cdd:COG1123   157 LALDPDLLIADEPTTALDVTTQAEILDLLRELqRERGTTVLLITHDLGVVAEIADRVVVMDDGRI 221

PRK11819

putative ABC transporter ATP-binding protein; Reviewed

6-181

2.74e-11

putative ABC transporter ATP-binding protein; Reviewed

Pssm-ID: 236992 [Multi-domain] Cd Length: 556 Bit Score: 65.91 E-value: 2.74e-11

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   6 SLRNITKRYPG---ITANdhVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEIsfdghplgveTPAQARELGIA 82
Cdd:PRK11819    8 TMNRVSKVVPPkkqILKD--ISLSFFPGAKIGVLGLNGAGKSTLLRIMAGVDKEFEGEA----------RPAPGIKVGYL 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  83 MvhQHFALFDTLSVTENVALGLS---------TGISA--AEIEREIRLLGEKYG-----------------LEV------ 128
Cdd:PRK11819   76 P--QEPQLDPEKTVRENVEEGVAevkaaldrfNEIYAayAEPDADFDALAAEQGelqeiidaadawdldsqLEIamdalr 153

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2549828669 129 --DPASVVMELSMGERQRVEILRALMTKPKLLILDEPTSVLTPQAVRKLFKTLHQ 181
Cdd:PRK11819  154 cpPWDAKVTKLSGGERRRVALCRLLLEKPDMLLLDEPTNHLDAESVAWLEQFLHD 208

ABC_Metallic_Cations

cd03235

ATP-binding cassette domain of the metal-type transporters; This family includes transporters ...

268-469

2.86e-11

Pssm-ID: 213202 [Multi-domain] Cd Length: 213 Bit Score: 62.94 E-value: 2.86e-11

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 268 IDNVSLAVRAGEIVGIAGISGNGQARFMAA-------ASGEylceadrVLLFNSPVGELDthaRRISglrYVPEQRLGHA 340
Cdd:cd03235    15 LEDVSFEVKPGEFLAIVGPNGAGKSTLLKAilgllkpTSGS-------IRVFGKPLEKER---KRIG---YVPQRRSIDR 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 341 AVPelsltantyLTGDSLVRSG--------FILRDRARSFANLVIER---FHVktpnAEKAAGSLSGGNLQKFIMGREIL 409
Cdd:cd03235    82 DFP---------ISVRDVVLMGlyghkglfRRLSKADKAKVDEALERvglSEL----ADRQIGELSGGQQQRVLLARALV 148

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2549828669 410 NRPRVLLVHQPTWGVDV-GAAAVIRNsLIRLRDDGAAIIVVSEEIDELFEISDRIAVMYRG 469
Cdd:cd03235   149 QDPDLLLLDEPFAGVDPkTQEDIYEL-LRELRREGMTILVVTHDLGLVLEYFDRVLLLNRT 208

PRK13409

ribosome biogenesis/translation initiation ATPase RLI;

9-208

3.13e-11

ribosome biogenesis/translation initiation ATPase RLI;

Pssm-ID: 184037 [Multi-domain] Cd Length: 590 Bit Score: 65.60 E-value: 3.13e-11

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   9 NITKRYPGItandhvSLDIAPG-----EVLAILGENGAGKSTLMKIIYGAARPDEGEISFDghplgvetpaqareLGIAM 83
Cdd:PRK13409  345 DLTKKLGDF------SLEVEGGeiyegEVIGIVGPNGIGKTTFAKLLAGVLKPDEGEVDPE--------------LKISY 404

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  84 VHQHFALFDTLSVTE---NVALGLSTGISAAEIEREIRL--LGEKYglevdpasvVMELSMGERQRVEILRALMTKPKLL 158
Cdd:PRK13409  405 KPQYIKPDYDGTVEDllrSITDDLGSSYYKSEIIKPLQLerLLDKN---------VKDLSGGELQRVAIAACLSRDADLY 475

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2549828669 159 ILDEPTS-------VLTPQAVRKLFKtlhqlsSEGVSILFISHKLDEIRELADRCVV 208
Cdd:PRK13409  476 LLDEPSAhldveqrLAVAKAIRRIAE------EREATALVVDHDIYMIDYISDRLMV 526

ABC_DrrA

cd03265

Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ...

268-471

3.62e-11

Pssm-ID: 213232 [Multi-domain] Cd Length: 220 Bit Score: 62.77 E-value: 3.62e-11

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 268 IDNVSLAVRAGEIVGIAGISGNGQ-------ARFMAAASGE-------YLCEADRVllfnspvgeldthARRISglrYVP 333
Cdd:cd03265    16 VRGVSFRVRRGEIFGLLGPNGAGKtttikmlTTLLKPTSGRatvaghdVVREPREV-------------RRRIG---IVF 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 334 EQRlghAAVPELSLTANTYLTGDSLVRSGFILRDRARSfanlVIERFHVkTPNAEKAAGSLSGGNLQKFIMGREILNRPR 413
Cdd:cd03265    80 QDL---SVDDELTGWENLYIHARLYGVPGAERRERIDE----LLDFVGL-LEAADRLVKTYSGGMRRRLEIARSLVHRPE 151

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2549828669 414 VLLVHQPTWGVDVGAaaviRNSLIR-----LRDDGAAIIVVSEEIDELFEISDRIAVMYRGAL 471
Cdd:cd03265   152 VLFLDEPTIGLDPQT----RAHVWEyieklKEEFGMTILLTTHYMEEAEQLCDRVAIIDHGRI 210

ABCC_MRP_domain1

cd03250

ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ...

23-213

3.72e-11

ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.

Pssm-ID: 213217 [Multi-domain] Cd Length: 204 Bit Score: 62.49 E-value: 3.72e-11

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  23 VSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGhplgvetpaqarelGIAMVHQHFALFDTlSVTENVAL 102
Cdd:cd03250    24 INLEVPKGELVAIVGPVGSGKSSLLSALLGELEKLSGSVSVPG--------------SIAYVSQEPWIQNG-TIRENILF 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 103 GLS-------TGISAAEIEREIRLL--------GEKyGlevdpasvvMELSMGERQRVEILRALMTKPKLLILDEPTSVL 167
Cdd:cd03250    89 GKPfdeeryeKVIKACALEPDLEILpdgdlteiGEK-G---------INLSGGQKQRISLARAVYSDADIYLLDDPLSAV 158

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 2549828669 168 TPQAVRKLF-KTLHQLSSEGVSILFISHKLDEIRElADRCVVLRAGK 213
Cdd:cd03250   159 DAHVGRHIFeNCILGLLLNNKTRILVTHQLQLLPH-ADQIVVLDNGR 204

MRP_assoc_pro

TIGR00957

multi drug resistance-associated protein (MRP); This model describes multi drug ...

4-214

5.58e-11

multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]

Pssm-ID: 188098 [Multi-domain] Cd Length: 1522 Bit Score: 65.35 E-value: 5.58e-11

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669    4 RLSLRNITKRY-PGIT-ANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGvETPAQARELGI 81
Cdd:TIGR00957 1284 RVEFRNYCLRYrEDLDlVLRHINVTIHGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGLNIA-KIGLHDLRFKI 1362

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   82 AMVHQHFALFdtlSVTENVALGLSTGISAAEIEREIRLLGEKYGLEVDPASVVME-------LSMGERQRVEILRALMTK 154
Cdd:TIGR00957 1363 TIIPQDPVLF---SGSLRMNLDPFSQYSDEEVWWALELAHLKTFVSALPDKLDHEcaeggenLSVGQRQLVCLARALLRK 1439

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  155 PKLLILDEPTSVLTPQAvRKLFKTLHQLSSEGVSILFISHKLDEIRELAdRCVVLRAGKV 214
Cdd:TIGR00957 1440 TKILVLDEATAAVDLET-DNLIQSTIRTQFEDCTVLTIAHRLNTIMDYT-RVIVLDKGEV 1497

PRK13546

teichoic acids export ABC transporter ATP-binding subunit TagH;

19-214

5.66e-11

teichoic acids export ABC transporter ATP-binding subunit TagH;

Pssm-ID: 184131 [Multi-domain] Cd Length: 264 Bit Score: 62.91 E-value: 5.66e-11

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  19 ANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHplgvetpaqarelgIAMVHQHFALFDTLSVTE 98
Cdd:PRK13546   39 ALDDISLKAYEGDVIGLVGINGSGKSTLSNIIGGSLSPTVGKVDRNGE--------------VSVIAISAGLSGQLTGIE 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  99 NVALG-LSTGISAAEIER------EIRLLGEkygLEVDPasvVMELSMGERQRVEILRALMTKPKLLILDEPTSVLTPQA 171
Cdd:PRK13546  105 NIEFKmLCMGFKRKEIKAmtpkiiEFSELGE---FIYQP---VKKYSSGMRAKLGFSINITVNPDILVIDEALSVGDQTF 178

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 2549828669 172 VRKLFKTLHQLSSEGVSILFISHKLDEIRELADRCVVLRAGKV 214
Cdd:PRK13546  179 AQKCLDKIYEFKEQNKTIFFVSHNLGQVRQFCTKIAWIEGGKL 221

PRK14271

phosphate ABC transporter ATP-binding protein; Provisional

3-215

8.49e-11

phosphate ABC transporter ATP-binding protein; Provisional

Pssm-ID: 172759 [Multi-domain] Cd Length: 276 Bit Score: 62.81 E-value: 8.49e-11

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   3 PRLSLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQAREL--- 79
Cdd:PRK14271   20 PAMAAVNLTLGFAGKTVLDQVSMGFPARAVTSLMGPTGSGKTTFLRTLNRMNDKVSGYRYSGDVLLGGRSIFNYRDVlef 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  80 --GIAMVHQHFALFdTLSVTENVAlglsTGISAAEI--EREIRLLGEKYGLEVDPASVVME--------LSMGERQRVEI 147
Cdd:PRK14271  100 rrRVGMLFQRPNPF-PMSIMDNVL----AGVRAHKLvpRKEFRGVAQARLTEVGLWDAVKDrlsdspfrLSGGQQQLLCL 174

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2549828669 148 LRALMTKPKLLILDEPTSVLTPQAVRKLFKTLHQLSSEgVSILFISHKLDEIRELADRCVVLRAGKVV 215
Cdd:PRK14271  175 ARTLAVNPEVLLLDEPTSALDPTTTEKIEEFIRSLADR-LTVIIVTHNLAQAARISDRAALFFDGRLV 241

PRK10938

putative molybdenum transport ATP-binding protein ModF; Provisional

2-194

1.08e-10

putative molybdenum transport ATP-binding protein ModF; Provisional

Pssm-ID: 182852 [Multi-domain] Cd Length: 490 Bit Score: 63.88 E-value: 1.08e-10

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   2 TPRLSLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGaarpdegeisfdGHPLG----VETPAQAR 77
Cdd:PRK10938  258 EPRIVLNNGVVSYNDRPILHNLSWQVNPGEHWQIVGPNGAGKSTLLSLITG------------DHPQGysndLTLFGRRR 325

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  78 ELG---------IAMVHQHFALFDTLSVT-ENVAL-GL--STGISAAEIEREiRLLGEKY----GLEVDPA-SVVMELSM 139
Cdd:PRK10938  326 GSGetiwdikkhIGYVSSSLHLDYRVSTSvRNVILsGFfdSIGIYQAVSDRQ-QKLAQQWldilGIDKRTAdAPFHSLSW 404

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2549828669 140 GERQRVEILRALMTKPKLLILDEPTSVLTP---QAVRKLfktLHQLSSEG-VSILFISH 194
Cdd:PRK10938  405 GQQRLALIVRALVKHPTLLILDEPLQGLDPlnrQLVRRF---VDVLISEGeTQLLFVSH 460

40850658_otr

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;

239-469

1.14e-10

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;

Pssm-ID: 411078 [Multi-domain] Cd Length: 351 Bit Score: 63.22 E-value: 1.14e-10

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 239 TVREGTAKAGEVVFEMRHVSapgstRVCGIDNVSLAVRAGEIVGIAGISGNGQARFMAAASGEYLCEADRVLLFNSPVGE 318
Cdd:NF000106    5 TISNGARNAVEVRGLVKHFG-----EVKAVDGVDLDVREGTVLGVLGP*GAA**RGALPAHV*GPDAGRRPWRF*TWCAN 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 319 LDTHARRISGLRYVpeqRLGHAAvpELSLTANTYLTGDSLVRSgfilRDRARSFANLVIERFHVkTPNAEKAAGSLSGGN 398
Cdd:NF000106   80 RRALRRTIG*HRPV---R*GRRE--SFSGRENLYMIGR*LDLS----RKDARARADELLERFSL-TEAAGRAAAKYSGGM 149

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2549828669 399 LQKFIMGREILNRPRVLLVHQPTWGVDVGAAAVIRNSLIRLRDDGAAIIVVSEEIDELFEISDRIAVMYRG 469
Cdd:NF000106  150 RRRLDLAASMIGRPAVLYLDEPTTGLDPRTRNEVWDEVRSMVRDGATVLLTTQYMEEAEQLAHELTVIDRG 220

ABCC_CFTR2

cd03289

ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator ...

4-214

1.25e-10

ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.

Pssm-ID: 213256 [Multi-domain] Cd Length: 275 Bit Score: 62.18 E-value: 1.25e-10

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   4 RLSLRNITKRYP--GITANDHVSLDIAPGEVLAILGENGAGKSTL----MKIIYgaarpDEGEISFDGHPLGVETPAQAR 77
Cdd:cd03289     2 QMTVKDLTAKYTegGNAVLENISFSISPGQRVGLLGRTGSGKSTLlsafLRLLN-----TEGDIQIDGVSWNSVPLQKWR 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  78 ElGIAMVHQHFALFdtlSVTENVALGLSTGISAAEIEREIRLLGEKYGLEVDPASV--VME-----LSMGERQRVEILRA 150
Cdd:cd03289    77 K-AFGVIPQKVFIF---SGTFRKNLDPYGKWSDEEIWKVAEEVGLKSVIEQFPGQLdfVLVdggcvLSHGHKQLMCLARS 152

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2549828669 151 LMTKPKLLILDEPTSVLTPQAVRKLFKTLHQlSSEGVSILFISHKLDEIRElADRCVVLRAGKV 214
Cdd:cd03289   153 VLSKAKILLLDEPSAHLDPITYQVIRKTLKQ-AFADCTVILSEHRIEAMLE-CQRFLVIEENKV 214

ABC_NrtD_SsuB_transporters

cd03293

ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ...

253-466

1.28e-10

Pssm-ID: 213260 [Multi-domain] Cd Length: 220 Bit Score: 61.33 E-value: 1.28e-10

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 253 EMRHVS---APGSTRVCGIDNVSLAVRAGEIVGIAGISGNGQ-------ARFMAAASGEylceadrVLLFNSPVGELDTH 322
Cdd:cd03293     2 EVRNVSktyGGGGGAVTALEDISLSVEEGEFVALVGPSGCGKstllriiAGLERPTSGE-------VLVDGEPVTGPGPD 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 323 arrisgLRYVPEQrlgHAAVPELSLTANTYLtGDSLVR-SGFILRDRARSFANLV-IERFHVKTPNAekaagsLSGGNLQ 400
Cdd:cd03293    75 ------RGYVFQQ---DALLPWLTVLDNVAL-GLELQGvPKAEARERAEELLELVgLSGFENAYPHQ------LSGGMRQ 138

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2549828669 401 KFIMGREILNRPRVLLVHQPTWGVDVGAAAVIRNSLIRL-RDDGAAIIVVSEEIDELFEISDRIAVM 466
Cdd:cd03293   139 RVALARALAVDPDVLLLDEPFSALDALTREQLQEELLDIwRETGKTVLLVTHDIDEAVFLADRVVVL 205

ABC_YhbG

cd03218

ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ...

261-469

1.35e-10

Pssm-ID: 213185 [Multi-domain] Cd Length: 232 Bit Score: 61.40 E-value: 1.35e-10

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 261 GSTRVcgIDNVSLAVRAGEIVGIAGISGNGQARFMAAASGEYLCEADRVLLFNSPVGELDTHARRISGLRYVPEQrlgHA 340
Cdd:cd03218    11 GKRKV--VNGVSLSVKQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGKILLDGQDITKLPMHKRARLGIGYLPQE---AS 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 341 AVPELSLTANTYLtgdsLVRSGFILRDRARSFANLVIERFHVkTPNAEKAAGSLSGGNLQKFIMGREILNRPRVLLVHQP 420
Cdd:cd03218    86 IFRKLTVEENILA----VLEIRGLSKKEREEKLEELLEEFHI-THLRKSKASSLSGGERRRVEIARALATNPKFLLLDEP 160

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 2549828669 421 TWGVDVGAAAVIRNSLIRLRDDGAAIIVVSEEIDELFEISDRIAVMYRG 469
Cdd:cd03218   161 FAGVDPIAVQDIQKIIKILKDRGIGVLITDHNVRETLSITDRAYIIYEG 209

PRK15056

manganese/iron ABC transporter ATP-binding protein;

16-217

2.17e-10

manganese/iron ABC transporter ATP-binding protein;

Pssm-ID: 185016 [Multi-domain] Cd Length: 272 Bit Score: 61.44 E-value: 2.17e-10

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  16 GITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFdghpLGVETPAQARELGIAMVHQHFALFDTLS 95
Cdd:PRK15056   19 GHTALRDASFTVPGGSIAALVGVNGSGKSTLFKALMGFVRLASGKISI----LGQPTRQALQKNLVAYVPQSEEVDWSFP 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  96 V-TENVALGLSTG------ISAAEIEREIRLLGEKYGLEVDPASVVMELSMGERQRVEILRALMTKPKLLILDEPTSVLT 168
Cdd:PRK15056   95 VlVEDVVMMGRYGhmgwlrRAKKRDRQIVTAALARVDMVEFRHRQIGELSGGQKKRVFLARAIAQQGQVILLDEPFTGVD 174

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 2549828669 169 PQAVRKLFKTLHQLSSEGVSILFISHKLDEIRELADRCVVLRaGKVVAS 217
Cdd:PRK15056  175 VKTEARIISLLRELRDEGKTMLVSTHNLGSVTEFCDYTVMVK-GTVLAS 222

CFTR_protein

TIGR01271

cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ...

4-201

2.96e-10

Pssm-ID: 273530 [Multi-domain] Cd Length: 1490 Bit Score: 63.01 E-value: 2.96e-10

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669    4 RLSLRNITKRYP--GITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARpDEGEISFDGHPLGVETPAQARElGI 81
Cdd:TIGR01271 1217 QMDVQGLTAKYTeaGRAVLQDLSFSVEGGQRVGLLGRTGSGKSTLLSALLRLLS-TEGEIQIDGVSWNSVTLQTWRK-AF 1294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   82 AMVHQHFALFdtlSVTENVALGLSTGISAAEIEREIRLLGEKYGLEVDPASV--VME-----LSMGERQRVEILRALMTK 154
Cdd:TIGR01271 1295 GVIPQKVFIF---SGTFRKNLDPYEQWSDEEIWKVAEEVGLKSVIEQFPDKLdfVLVdggyvLSNGHKQLMCLARSILSK 1371

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*..
gi 2549828669  155 PKLLILDEPTSVLTPQAVRKLFKTLHQLSSEGVSILfISHKLDEIRE 201
Cdd:TIGR01271 1372 AKILLLDEPSAHLDPVTLQIIRKTLKQSFSNCTVIL-SEHRVEALLE 1417

ABC_MJ0796_LolCDE_FtsE

cd03255

ATP-binding cassette domain of the transporters involved in export of lipoprotein and ...

253-471

3.38e-10

Pssm-ID: 213222 [Multi-domain] Cd Length: 218 Bit Score: 59.81 E-value: 3.38e-10

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 253 EMRHVS---APGSTRVCGIDNVSLAVRAGEIVGIAGISGNGQARFMAAASGeyLCEAD--RVLLFNSPVGELDTHARriS 327
Cdd:cd03255     2 ELKNLSktyGGGGEKVQALKGVSLSIEKGEFVAIVGPSGSGKSTLLNILGG--LDRPTsgEVRVDGTDISKLSEKEL--A 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 328 GLR-----YVPEQrlgHAAVPELSLTANT----YLTGdslvRSGFILRDRARSfanlVIERFHVKTpNAEKAAGSLSGGN 398
Cdd:cd03255    78 AFRrrhigFVFQS---FNLLPDLTALENVelplLLAG----VPKKERRERAEE----LLERVGLGD-RLNHYPSELSGGQ 145

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2549828669 399 LQKFIMGREILNRPRVLLVHQPTWGVDVGAAAVIRNSLIRL-RDDGAAIIVVSEEiDELFEISDRIAVMYRGAL 471
Cdd:cd03255   146 QQRVAIARALANDPKIILADEPTGNLDSETGKEVMELLRELnKEAGTTIVVVTHD-PELAEYADRIIELRDGKI 218

ABCC_CFTR1

cd03291

ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The ...

23-212

3.41e-10

ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The CFTR subfamily domain 1. The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits, or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.

Pssm-ID: 213258 [Multi-domain] Cd Length: 282 Bit Score: 61.03 E-value: 3.41e-10

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  23 VSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHplgvetpaqarelgIAMVHQhFALFDTLSVTENVAL 102
Cdd:cd03291    56 INLKIEKGEMLAITGSTGSGKTSLLMLILGELEPSEGKIKHSGR--------------ISFSSQ-FSWIMPGTIKENIIF 120

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 103 GLS-------TGISAAEIEREIRLLGEKYGLEVDPASVVmeLSMGERQRVEILRALMTKPKLLILDEPTSVLTPQAVRKL 175
Cdd:cd03291   121 GVSydeyrykSVVKACQLEEDITKFPEKDNTVLGEGGIT--LSGGQRARISLARAVYKDADLYLLDSPFGYLDVFTEKEI 198

                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 2549828669 176 F-KTLHQLSSEGVSILfISHKLDEIRElADRCVVLRAG 212
Cdd:cd03291   199 FeSCVCKLMANKTRIL-VTSKMEHLKK-ADKILILHEG 234

PTZ00265

multidrug resistance protein (mdr1); Provisional

57-217

4.37e-10

multidrug resistance protein (mdr1); Provisional

Pssm-ID: 240339 [Multi-domain] Cd Length: 1466 Bit Score: 62.35 E-value: 4.37e-10

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   57 DEGEISFDGHPLGVETPAQARELgIAMVHQHFALFDtLSVTENVALG--------LSTGISAAEIEREIRLLGEKYGLEV 128
Cdd:PTZ00265  1275 NSGKILLDGVDICDYNLKDLRNL-FSIVSQEPMLFN-MSIYENIKFGkedatredVKRACKFAAIDEFIESLPNKYDTNV 1352

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  129 DPASvvMELSMGERQRVEILRALMTKPKLLILDEPTSVLTPQAVRKLFKTLHQLSSEG-VSILFISHKLDEIRElADRCV 207
Cdd:PTZ00265  1353 GPYG--KSLSGGQKQRIAIARALLREPKILLLDEATSSLDSNSEKLIEKTIVDIKDKAdKTIITIAHRIASIKR-SDKIV 1429

                          170
                   ....*....|....
gi 2549828669  208 VL----RAGKVVAS 217
Cdd:PTZ00265  1430 VFnnpdRTGSFVQA 1443

PRK14247

phosphate ABC transporter ATP-binding protein; Provisional

261-471

4.37e-10

phosphate ABC transporter ATP-binding protein; Provisional

Pssm-ID: 172735 [Multi-domain] Cd Length: 250 Bit Score: 60.31 E-value: 4.37e-10

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 261 GSTRVcgIDNVSLAVRAGEIVGIAGISGNGQARFM------------AAASGEYLCEADRVllFNSPVGELdthARRISG 328
Cdd:PRK14247   14 GQVEV--LDGVNLEIPDNTITALMGPSGSGKSTLLrvfnrlielypeARVSGEVYLDGQDI--FKMDVIEL---RRRVQM 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 329 LRYVPEqrlghaAVPELSLTANTYL--TGDSLVRSGFILRDRAR---SFANLVIErfhVKTpNAEKAAGSLSGGNLQKFI 403
Cdd:PRK14247   87 VFQIPN------PIPNLSIFENVALglKLNRLVKSKKELQERVRwalEKAQLWDE---VKD-RLDAPAGKLSGGQQQRLC 156

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2549828669 404 MGREILNRPRVLLVHQPTWGVDVGAAAVIRNSLIRLRDDgAAIIVVSEEIDELFEISDRIAVMYRGAL 471
Cdd:PRK14247  157 IARALAFQPEVLLADEPTANLDPENTAKIESLFLELKKD-MTIVLVTHFPQQAARISDYVAFLYKGQI 223

ABCC_bacteriocin_exporters

cd03245

ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ...

268-471

5.60e-10

Pssm-ID: 213212 [Multi-domain] Cd Length: 220 Bit Score: 59.14 E-value: 5.60e-10

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 268 IDNVSLAVRAGEIVGIAGISGNGQARFMAAASGEYLCEADRVLLFNSPVGELDTHARRiSGLRYVPEQrlghaavPEL-- 345
Cdd:cd03245    20 LDNVSLTIRAGEKVAIIGRVGSGKSTLLKLLAGLYKPTSGSVLLDGTDIRQLDPADLR-RNIGYVPQD-------VTLfy 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 346 -SLTANTYLtGDSLVRSGFILrdRARSFAnlVIERFHVKTPN------AEKAAGsLSGGNLQKFIMGREILNRPRVLLVH 418
Cdd:cd03245    92 gTLRDNITL-GAPLADDERIL--RAAELA--GVTDFVNKHPNgldlqiGERGRG-LSGGQRQAVALARALLNDPPILLLD 165

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2549828669 419 QPTWGVDVGAAAVIRNSLIRLRDDGAAIIVVSEEidELFEISDRIAVMYRGAL 471
Cdd:cd03245   166 EPTSAMDMNSEERLKERLRQLLGDKTLIIITHRP--SLLDLVDRIIVMDSGRI 216

ABC_PotA_N

cd03300

ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ...

253-487

7.01e-10

Pssm-ID: 213267 [Multi-domain] Cd Length: 232 Bit Score: 59.17 E-value: 7.01e-10

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 253 EMRHVS-APGSTRVcgIDNVSLAVRAGEIVGIAGISGNGQ-------ARFMAAASGEylceadrVLLFNSPVGELDTHAR 324
Cdd:cd03300     2 ELENVSkFYGGFVA--LDGVSLDIKEGEFFTLLGPSGCGKttllrliAGFETPTSGE-------ILLDGKDITNLPPHKR 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 325 RISGL--RYvpeqrlghAAVPELSLTANTyltgdslvrsGFILRDRARSFANL---VIERFH-VKTPN-AEKAAGSLSGG 397
Cdd:cd03300    73 PVNTVfqNY--------ALFPHLTVFENI----------AFGLRLKKLPKAEIkerVAEALDlVQLEGyANRKPSQLSGG 134

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 398 NLQKFIMGREILNRPRVLLVHQPTWGVDVGAAAVIRNSLIRLRDD-GAAIIVVSEEIDELFEISDRIAVMYRGalspavp 476
Cdd:cd03300   135 QQQRVAIARALVNEPKVLLLDEPLGALDLKLRKDMQLELKRLQKElGITFVFVTHDQEEALTMSDRIAVMNKG------- 207

                         250
                  ....*....|.
gi 2549828669 477 kptiSIEEVGR 487
Cdd:cd03300   208 ----KIQQIGT 214

rim_protein

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...

258-471

8.69e-10

Pssm-ID: 130324 [Multi-domain] Cd Length: 2272 Bit Score: 61.57 E-value: 8.69e-10

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  258 SAPGSTRVCgidnvsLAVRAGEIVGIAGISGNGQARFMAAASGEY-LCEADRVLLFNSPVGEL-DTHarriSGLRYVPEq 335
Cdd:TIGR01257 1951 SSPAVDRLC------VGVRPGECFGLLGVNGAGKTTTFKMLTGDTtVTSGDATVAGKSILTNIsDVH----QNMGYCPQ- 2019

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  336 rlgHAAVPELsltantyLTGdslvRSGFILRDRARSFANLVIER---FHVK----TPNAEKAAGSLSGGNLQKFIMGREI 408
Cdd:TIGR01257 2020 ---FDAIDDL-------LTG----REHLYLYARLRGVPAEEIEKvanWSIQslglSLYADRLAGTYSGGNKRKLSTAIAL 2085

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2549828669  409 LNRPRVLLVHQPTWGVDVGAAAVIRNSLIRLRDDGAAIIVVSEEIDELFEISDRIAVMYRGAL 471
Cdd:TIGR01257 2086 IGCPPLVLLDEPTTGMDPQARRMLWNTIVSIIREGRAVVLTSHSMEECEALCTRLAIMVKGAF 2148

ABC_drug_resistance_like

cd03264

ABC-type multidrug transport system, ATPase component; The biological function of this family ...

266-471

1.11e-09

Pssm-ID: 213231 [Multi-domain] Cd Length: 211 Bit Score: 58.36 E-value: 1.11e-09

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 266 CGIDNVSLAVRAGeIVGIAGISGNGQARFMAAASGEYLCEADRVLLFNSPVGELDTHARRISGlrYVPEQRLGHAavpel 345
Cdd:cd03264    14 RALDGVSLTLGPG-MYGLLGPNGAGKTTLMRILATLTPPSSGTIRIDGQDVLKQPQKLRRRIG--YLPQEFGVYP----- 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 346 SLTANTYLtgDSLVRSGFILRDRARSFANLVIERFHVkTPNAEKAAGSLSGGNLQKFIMGREILNRPRVLLVHQPTWGVD 425
Cdd:cd03264    86 NFTVREFL--DYIAWLKGIPSKEVKARVDEVLELVNL-GDRAKKKIGSLSGGMRRRVGIAQALVGDPSILIVDEPTAGLD 162

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 2549828669 426 VGAAAVIRNSLIRLRDDgaAIIVVSEEIDELFE-ISDRIAVMYRGAL 471
Cdd:cd03264   163 PEERIRFRNLLSELGED--RIVILSTHIVEDVEsLCNQVAVLNKGKL 207

livF

PRK11614

high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;

264-469

1.28e-09

high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;

Pssm-ID: 183231 [Multi-domain] Cd Length: 237 Bit Score: 58.74 E-value: 1.28e-09

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 264 RVCGIDNVSLAVRAGEIVGIAGISGNGQARFMAAASGEYLCEADRVLLFNSPVGELDThaRRIsglryvpeQRLGHAAVP 343
Cdd:PRK11614   17 KIQALHEVSLHINQGEIVTLIGANGAGKTTLLGTLCGDPRATSGRIVFDGKDITDWQT--AKI--------MREAVAIVP 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 344 ELSLTANTYLTGDSLVRSGFIL-RDRARSFANLVIERFHVKTPNAEKAAGSLSGGNLQKFIMGREILNRPRVLLVHQPTW 422
Cdd:PRK11614   87 EGRRVFSRMTVEENLAMGGFFAeRDQFQERIKWVYELFPRLHERRIQRAGTMSGGEQQMLAIGRALMSQPRLLLLDEPSL 166

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 2549828669 423 GVDVGAAAVIRNSLIRLRDDGAAIIVVSEEIDELFEISDRIAVMYRG 469
Cdd:PRK11614  167 GLAPIIIQQIFDTIEQLREQGMTIFLVEQNANQALKLADRGYVLENG 213

3a01205

TIGR00956

Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]

22-215

1.40e-09

Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]

Pssm-ID: 273362 [Multi-domain] Cd Length: 1394 Bit Score: 60.89 E-value: 1.40e-09

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   22 HVSLDIAPGEVLAILGENGAGKSTLMKII----YGAARPDEGEISFDGHPLGVETPAQAREL---GIAMVH-QHFALFDT 93
Cdd:TIGR00956   79 PMDGLIKPGELTVVLGRPGSGCSTLLKTIasntDGFHIGVEGVITYDGITPEEIKKHYRGDVvynAETDVHfPHLTVGET 158

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   94 LsvteNVALGLST------GISAAE-IEREIRLLGEKYGLEVDPASVVME-----LSMGERQRVEILRALMTKPKLLILD 161
Cdd:TIGR00956  159 L----DFAARCKTpqnrpdGVSREEyAKHIADVYMATYGLSHTRNTKVGNdfvrgVSGGERKRVSIAEASLGGAKIQCWD 234

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 2549828669  162 EPT----SVLTPQAVRKLFKTLHQL-SSEGVSILFIShklDEIRELADRCVVLRAGKVV 215
Cdd:TIGR00956  235 NATrgldSATALEFIRALKTSANILdTTPLVAIYQCS---QDAYELFDKVIVLYEGYQI 290

PRK11819

putative ABC transporter ATP-binding protein; Reviewed

3-164

1.92e-09

putative ABC transporter ATP-binding protein; Reviewed

Pssm-ID: 236992 [Multi-domain] Cd Length: 556 Bit Score: 59.75 E-value: 1.92e-09

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   3 PRL-----SLRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISfdghpLGvETpaqar 77
Cdd:PRK11819  318 PRLgdkviEAENLSKSFGDRLLIDDLSFSLPPGGIVGIIGPNGAGKSTLFKMITGQEQPDSGTIK-----IG-ET----- 386

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  78 eLGIAMVHQ-HFALFDTLSVTENVALGLstgisaaeierEIRLLGEKyglEV--------------DPASVVMELSMGER 142
Cdd:PRK11819  387 -VKLAYVDQsRDALDPNKTVWEEISGGL-----------DIIKVGNR---EIpsrayvgrfnfkggDQQKKVGVLSGGER 451

                         170       180
                  ....*....|....*....|..
gi 2549828669 143 QRVEILRALMTKPKLLILDEPT 164
Cdd:PRK11819  452 NRLHLAKTLKQGGNVLLLDEPT 473

ABCC_SUR1_N

cd03290

ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The ...

15-212

2.03e-09

ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The sulfonylurea receptor SUR is an ATP transporter of the ABCC/MRP family with tandem ATPase binding domains. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.

Pssm-ID: 213257 [Multi-domain] Cd Length: 218 Bit Score: 57.73 E-value: 2.03e-09

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  15 PGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHPLGVETPAQARELG---IAMVHQHFALF 91
Cdd:cd03290    12 SGLATLSNINIRIPTGQLTMIVGQVGCGKSSLLLAILGEMQTLEGKVHWSNKNESEPSFEATRSRNrysVAYAAQKPWLL 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  92 DTlSVTENVALG-------LSTGISAAEIEREIRLLgeKYGLEVDPASVVMELSMGERQRVEILRALMTKPKLLILDEPT 164
Cdd:cd03290    92 NA-TVEENITFGspfnkqrYKAVTDACSLQPDIDLL--PFGDQTEIGERGINLSGGQRQRICVARALYQNTNIVFLDDPF 168

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 2549828669 165 SVLTPQAVRKLFKT--LHQLSSEGVSILFISHKLDEIRElADRCVVLRAG 212
Cdd:cd03290   169 SALDIHLSDHLMQEgiLKFLQDDKRTLVLVTHKLQYLPH-ADWIIAMKDG 217

ABCG_White

cd03234

White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ...

268-469

2.55e-09

Pssm-ID: 213201 [Multi-domain] Cd Length: 226 Bit Score: 57.67 E-value: 2.55e-09

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 268 IDNVSLAVRAGEIVGIAGISGNGQARFMAAASGEYLCEAD---RVLLFNSPVgELDTHARRISglrYVPEQrlgHAAVPe 344
Cdd:cd03234    23 LNDVSLHVESGQVMAILGSSGSGKTTLLDAISGRVEGGGTtsgQILFNGQPR-KPDQFQKCVA---YVRQD---DILLP- 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 345 lSLTANTYLTGDSLVRSGFILRDRARSFANLVIERFHVK-TPNAEKAAGSLSGGNLQKFIMGREILNRPRVLLVHQPTWG 423
Cdd:cd03234    95 -GLTVRETLTYTAILRLPRKSSDAIRKKRVEDVLLRDLAlTRIGGNLVKGISGGERRRVSIAVQLLWDPKVLILDEPTSG 173

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 2549828669 424 VDVGAAAVIRNSLIRL-RDDGAAIIVVSEEIDELFEISDRIAVMYRG 469
Cdd:cd03234   174 LDSFTALNLVSTLSQLaRRNRIVILTIHQPRSDLFRLFDRILLLSSG 220

PTZ00265

multidrug resistance protein (mdr1); Provisional

23-227

3.49e-09

multidrug resistance protein (mdr1); Provisional

Pssm-ID: 240339 [Multi-domain] Cd Length: 1466 Bit Score: 59.66 E-value: 3.49e-09

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   23 VSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISF-DGHPLGVETPAQARElGIAMVHQHFALFDTlSVTENVA 101
Cdd:PTZ00265   404 LNFTLTEGKTYAFVGESGCGKSTILKLIERLYDPTEGDIIInDSHNLKDINLKWWRS-KIGVVSQDPLLFSN-SIKNNIK 481

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  102 LGL----------------------------------------------STGISAAEIERE------------------- 116
Cdd:PTZ00265   482 YSLyslkdlealsnyynedgndsqenknkrnscrakcagdlndmsnttdSNELIEMRKNYQtikdsevvdvskkvlihdf 561

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  117 IRLLGEKYGLEVdpASVVMELSMGERQRVEILRALMTKPKLLILDEPTSVLTPQAVRKLFKTLHQLS-SEGVSILFISHK 195
Cdd:PTZ00265   562 VSALPDKYETLV--GSNASKLSGGQKQRISIARAIIRNPKILILDEATSSLDNKSEYLVQKTINNLKgNENRITIIIAHR 639

                          250       260       270
                   ....*....|....*....|....*....|....*...
gi 2549828669  196 LDEIRE------LADRCVVLRAGKVVASVDPKAESEEN 227
Cdd:PTZ00265   640 LSTIRYantifvLSNRERGSTVDVDIIGEDPTKDNKEN 677

ABC_RNaseL_inhibitor_domain2

cd03237

The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...

26-167

3.65e-09

The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity of more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.

Pssm-ID: 213204 [Multi-domain] Cd Length: 246 Bit Score: 57.42 E-value: 3.65e-09

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  26 DIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGE-------ISFDGHPLGVETPAQARELgiamvhqhfaLFdtlSVTE 98
Cdd:cd03237    21 SISESEVIGILGPNGIGKTTFIKMLAGVLKPDEGDieieldtVSYKPQYIKADYEGTVRDL----------LS---SITK 87

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2549828669  99 NVAlglstgiSAAEIEREIrllGEKYGLEVDPASVVMELSMGERQRVEILRALMTKPKLLILDEPTSVL 167
Cdd:cd03237    88 DFY-------THPYFKTEI---AKPLQIEQILDREVPELSGGELQRVAIAACLSKDADIYLLDEPSAYL 146

ABC_subfamily_A

cd03263

ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ...

268-471

3.70e-09

Pssm-ID: 213230 [Multi-domain] Cd Length: 220 Bit Score: 56.74 E-value: 3.70e-09

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 268 IDNVSLAVRAGEIVGIAGISGNGQARFMAAASGEYLCEADRVLLFNSPVGELDTHARRISGlrYVPEqrlgHAAVPELsL 347
Cdd:cd03263    18 VDDLSLNVYKGEIFGLLGHNGAGKTTTLKMLTGELRPTSGTAYINGYSIRTDRKAARQSLG--YCPQ----FDALFDE-L 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 348 TANTYLTGDSLVRSGFilRDRARSFANLVIErfHVK-TPNAEKAAGSLSGGNLQKFIMGREILNRPRVLLVHQPTWGVDV 426
Cdd:cd03263    91 TVREHLRFYARLKGLP--KSEIKEEVELLLR--VLGlTDKANKRARTLSGGMKRKLSLAIALIGGPSVLLLDEPTSGLDP 166

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 2549828669 427 GAAAVIRNSLIRLRDdGAAIIVVSEEIDELFEISDRIAVMYRGAL 471
Cdd:cd03263   167 ASRRAIWDLILEVRK-GRSIILTTHSMDEAEALCDRIAIMSDGKL 210

oppD

PRK09473

oligopeptide transporter ATP-binding component; Provisional

265-469

8.53e-09

oligopeptide transporter ATP-binding component; Provisional

Pssm-ID: 181888 [Multi-domain] Cd Length: 330 Bit Score: 57.04 E-value: 8.53e-09

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 265 VCGIDNVSLAVRAGEIVGIAGISGNG--QARF----MAAASGEYLCEAdrvlLFNspvgeldthARRISGLryvPEQRLG 338
Cdd:PRK09473   29 VTAVNDLNFSLRAGETLGIVGESGSGksQTAFalmgLLAANGRIGGSA----TFN---------GREILNL---PEKELN 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 339 HAAVPELSL-------TANTYL-TGDSLVRsgfILR-----DRARSFANLVIERFHVKTPNAEKAAG----SLSGGNLQK 401
Cdd:PRK09473   93 KLRAEQISMifqdpmtSLNPYMrVGEQLME---VLMlhkgmSKAEAFEESVRMLDAVKMPEARKRMKmyphEFSGGMRQR 169

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2549828669 402 FIMGREILNRPRVLLVHQPTWGVDVGAAAVIRNSLIRLRDD-GAAIIVVSEEIDELFEISDRIAVMYRG 469
Cdd:PRK09473  170 VMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREfNTAIIMITHDLGVVAGICDKVLVMYAG 238

uvra

TIGR00630

excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of ...

137-220

9.76e-09

excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of proteins of which all members for which functions are known except the UvrA proteins are involved in the transport of material through membranes. UvrA orthologs are involved in the recognition of DNA damage as a step in nucleotide excision repair. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]

Pssm-ID: 273184 [Multi-domain] Cd Length: 925 Bit Score: 58.10 E-value: 9.76e-09

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 137 LSMGERQRVEILRALM---TKPKLLILDEPTSVLTPQAVRKLFKTLHQLSSEGVSILFISHKLDEIRElADRCVVL---- 209
Cdd:TIGR00630 830 LSGGEAQRIKLAKELSkrsTGRTLYILDEPTTGLHFDDIKKLLEVLQRLVDKGNTVVVIEHNLDVIKT-ADYIIDLgpeg 908

                          90
                  ....*....|...
gi 2549828669 210 --RAGKVVASVDP 220
Cdd:TIGR00630 909 gdGGGTVVASGTP 921

ABC_UvrA_II

cd03271

ATP-binding cassette domain II of the excision repair protein UvrA; Nucleotide excision repair ...

136-220

1.26e-08

ATP-binding cassette domain II of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins and UvrB having one ATP binding site that is structurally related to that of helicases.

Pssm-ID: 213238 [Multi-domain] Cd Length: 261 Bit Score: 56.08 E-value: 1.26e-08

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 136 ELSMGERQRVEILRALM---TKPKLLILDEPTSVLTPQAVRKLFKTLHQLSSEGVSILFISHKLDEIReLADRCVVL--- 209
Cdd:cd03271   169 TLSGGEAQRIKLAKELSkrsTGKTLYILDEPTTGLHFHDVKKLLEVLQRLVDKGNTVVVIEHNLDVIK-CADWIIDLgpe 247

                          90
                  ....*....|....
gi 2549828669 210 ---RAGKVVASVDP 220
Cdd:cd03271   248 ggdGGGQVVASGTP 261

PTZ00243

ABC transporter; Provisional

23-214

1.26e-08

ABC transporter; Provisional

Pssm-ID: 240327 [Multi-domain] Cd Length: 1560 Bit Score: 57.87 E-value: 1.26e-08

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   23 VSLDIAPGEVLAILGENGAGKSTL----MKIIYGAArpdeGEISFDGHPLGVETPAQARELgIAMVHQHFALFDTlSVTE 98
Cdd:PTZ00243  1329 VSFRIAPREKVGIVGRTGSGKSTLlltfMRMVEVCG----GEIRVNGREIGAYGLRELRRQ-FSMIPQDPVLFDG-TVRQ 1402

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   99 NVALGLSTgiSAAEIEREIRLLG-------EKYGLEvdpaSVVME----LSMGERQRVEILRALMTKPKLLIL-DEPTSV 166
Cdd:PTZ00243  1403 NVDPFLEA--SSAEVWAALELVGlrervasESEGID----SRVLEggsnYSVGQRQLMCMARALLKKGSGFILmDEATAN 1476

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*...
gi 2549828669  167 LTPQAVRKLFKTLHQLSSeGVSILFISHKLDEIRELaDRCVVLRAGKV 214
Cdd:PTZ00243  1477 IDPALDRQIQATVMSAFS-AYTVITIAHRLHTVAQY-DKIIVMDHGAV 1522

ABCC_Hemolysin

cd03252

ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ...

268-471

1.53e-08

Pssm-ID: 213219 [Multi-domain] Cd Length: 237 Bit Score: 55.18 E-value: 1.53e-08

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 268 IDNVSLAVRAGEIVGIAGISGNGQARFMAAASGEYLCEADRVLLFNSPVGELD-THARRISGlrYVPEQRLghaaVPELS 346
Cdd:cd03252    18 LDNISLRIKPGEVVGIVGRSGSGKSTLTKLIQRFYVPENGRVLVDGHDLALADpAWLRRQVG--VVLQENV----LFNRS 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 347 LTANTYLTGDSLVRSGFILRDR---ARSFANLVIERFhvKTPNAEKAAGsLSGGNLQKFIMGREILNRPRVLLVHQPTWG 423
Cdd:cd03252    92 IRDNIALADPGMSMERVIEAAKlagAHDFISELPEGY--DTIVGEQGAG-LSGGQRQRIAIARALIHNPRILIFDEATSA 168

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 2549828669 424 VDVGAAAVIRNSLIRLRdDGAAIIVVSEEIDELfEISDRIAVMYRGAL 471
Cdd:cd03252   169 LDYESEHAIMRNMHDIC-AGRTVIIIAHRLSTV-KNADRIIVMEKGRI 214

ABC_CysA_sulfate_importer

cd03296

ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ...

268-486

2.06e-08

Pssm-ID: 213263 [Multi-domain] Cd Length: 239 Bit Score: 55.04 E-value: 2.06e-08

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 268 IDNVSLAVRAGEIVGIAGISGNGQARFMAAASGEYLCEADRVLLFNSPVGELDTHARRISglrYVPEQrlgHAAVPELSL 347
Cdd:cd03296    18 LDDVSLDIPSGELVALLGPSGSGKTTLLRLIAGLERPDSGTILFGGEDATDVPVQERNVG---FVFQH---YALFRHMTV 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 348 TANTyltgdslvrsGFILRDRARSF---ANLVIERFH-----VKTPN-AEKAAGSLSGGNLQKFIMGREILNRPRVLLVH 418
Cdd:cd03296    92 FDNV----------AFGLRVKPRSErppEAEIRAKVHellklVQLDWlADRYPAQLSGGQRQRVALARALAVEPKVLLLD 161

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2549828669 419 QPTWGVDVGAAAVIRNSLIRLRDD-GAAIIVVSEEIDELFEISDRIAVMYRGAlspavpkptisIEEVG 486
Cdd:cd03296   162 EPFGALDAKVRKELRRWLRRLHDElHVTTVFVTHDQEEALEVADRVVVMNKGR-----------IEQVG 219

ABC_RNaseL_inhibitor_domain1

cd03236

The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...

28-204

3.08e-08

The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI s are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLIs have an N-terminal Fe-S domain and two nucleotide binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.

Pssm-ID: 213203 [Multi-domain] Cd Length: 255 Bit Score: 54.68 E-value: 3.08e-08

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  28 APGEVLAILGENGAGKSTLMKIIYGAARPDEGEisFDGHP---------LGVETP---AQARELGIAMVH--QHFALFDT 93
Cdd:cd03236    24 REGQVLGLVGPNGIGKSTALKILAGKLKPNLGK--FDDPPdwdeildefRGSELQnyfTKLLEGDVKVIVkpQYVDLIPK 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  94 lSVTENVALGLSTGISAAEIEREIRLLGEKYGLEVDpasvVMELSMGERQRVEILRALMTKPKLLILDEPTSVLTPQAVR 173
Cdd:cd03236   102 -AVKGKVGELLKKKDERGKLDELVDQLELRHVLDRN----IDQLSGGELQRVAIAAALARDADFYFFDEPSSYLDIKQRL 176

                         170       180       190
                  ....*....|....*....|....*....|.
gi 2549828669 174 KLFKTLHQLSSEGVSILFISHKLDEIRELAD 204
Cdd:cd03236   177 NAARLIRELAEDDNYVLVVEHDLAVLDYLSD 207

PRK10636

putative ABC transporter ATP-binding protein; Provisional

21-205

3.15e-08

putative ABC transporter ATP-binding protein; Provisional

Pssm-ID: 236729 [Multi-domain] Cd Length: 638 Bit Score: 56.33 E-value: 3.15e-08

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  21 DHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGHP----LGVETPA--------------QAREL--- 79
Cdd:PRK10636   18 DNATATINPGQKVGLVGKNGCGKSTLLALLKNEISADGGSYTFPGNWqlawVNQETPAlpqpaleyvidgdrEYRQLeaq 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  80 -----------GIAMVHQHFALFDTLSVTENVALGLS-TGISAAEIEREIRllgekyglevdpasvvmELSMGERQRVEI 147
Cdd:PRK10636   98 lhdanerndghAIATIHGKLDAIDAWTIRSRAASLLHgLGFSNEQLERPVS-----------------DFSGGWRMRLNL 160

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2549828669 148 LRALMTKPKLLILDEPTSVLTPQAVRKLFKTLHqlSSEGVSILfISHKLDEIRELADR 205
Cdd:PRK10636  161 AQALICRSDLLLLDEPTNHLDLDAVIWLEKWLK--SYQGTLIL-ISHDRDFLDPIVDK 215

ABC_tran

pfam00005

ABC transporter; ABC transporters for a large family of proteins responsible for translocation ...

268-421

3.25e-08

Pssm-ID: 394964 [Multi-domain] Cd Length: 150 Bit Score: 52.65 E-value: 3.25e-08

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 268 IDNVSLAVRAGEIVGIAGISGNGQARFMAAASGEYLCEADRVLLFNSPVGELDTHARRiSGLRYVPEQrlgHAAVPELSL 347
Cdd:pfam00005   1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQDLTDDERKSLR-KEIGYVFQD---PQLFPRLTV 76

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2549828669 348 TANTYLTGDSLVRSGFILRDRARSFANLVIERFHVKTPnAEKAAGSLSGGNLQKFIMGREILNRPRVLLVHQPT 421
Cdd:pfam00005  77 RENLRLGLLLKGLSKREKDARAEEALEKLGLGDLADRP-VGERPGTLSGGQRQRVAIARALLTKPKLLLLDEPT 149

PRK11147

ABC transporter ATPase component; Reviewed

7-167

4.43e-08

ABC transporter ATPase component; Reviewed

Pssm-ID: 236861 [Multi-domain] Cd Length: 635 Bit Score: 55.73 E-value: 4.43e-08

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   7 LRNITKRYPGITANDHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISfdghplgVETpaqarELGIAMVHQ 86
Cdd:PRK11147  322 MENVNYQIDGKQLVKDFSAQVQRGDKIALIGPNGCGKTTLLKLMLGQLQADSGRIH-------CGT-----KLEVAYFDQ 389

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  87 HFALFD-TLSVTENVALGLSTgISAAEIEREIrlLGEKYGLEVDPASV---VMELSMGERQRVeILRALMTKP-KLLILD 161
Cdd:PRK11147  390 HRAELDpEKTVMDNLAEGKQE-VMVNGRPRHV--LGYLQDFLFHPKRAmtpVKALSGGERNRL-LLARLFLKPsNLLILD 465


                  ....*.
gi 2549828669 162 EPTSVL 167
Cdd:PRK11147  466 EPTNDL 471

PLN03073

ABC transporter F family; Provisional

33-214

4.70e-08

ABC transporter F family; Provisional

Pssm-ID: 215558 [Multi-domain] Cd Length: 718 Bit Score: 55.64 E-value: 4.70e-08

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  33 LAILGENGAGKSTLMKIIYGAARPDEGeisfdghplgveTPAQARELGIAMVHQHFAlfDTLSVTENVALGLSTGISAAe 112
Cdd:PLN03073  538 IAMVGPNGIGKSTILKLISGELQPSSG------------TVFRSAKVRMAVFSQHHV--DGLDLSSNPLLYMMRCFPGV- 602

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 113 IEREIRLLGEKYGLEVDPASVVM-ELSMGERQRVEILRALMTKPKLLILDEPTSVLTPQAVRKLFKTLHQLSSegvSILF 191
Cdd:PLN03073  603 PEQKLRAHLGSFGVTGNLALQPMyTLSGGQKSRVAFAKITFKKPHILLLDEPSNHLDLDAVEALIQGLVLFQG---GVLM 679

                         170       180
                  ....*....|....*....|...
gi 2549828669 192 ISHKLDEIRELADRCVVLRAGKV 214
Cdd:PLN03073  680 VSHDEHLISGSVDELWVVSEGKV 702

cbiO

PRK13644

energy-coupling factor transporter ATPase;

268-469

6.29e-08

energy-coupling factor transporter ATPase;

Pssm-ID: 106587 [Multi-domain] Cd Length: 274 Bit Score: 53.84 E-value: 6.29e-08

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 268 IDNVSLAVRAGEIVGIAGISGNGQARFMAAASGEYLCEADRVLLFNSPVGELDT--HARRISGLRYV-PE-QRLGHAAVP 343
Cdd:PRK13644   18 LENINLVIKKGEYIGIIGKNGSGKSTLALHLNGLLRPQKGKVLVSGIDTGDFSKlqGIRKLVGIVFQnPEtQFVGRTVEE 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 344 ELSLTAntyltgDSLVRSGFILRDRA-RSFANLVIERFHVKTPNaekaagSLSGGNLQKFIMGREILNRPRVLLVHQPTW 422
Cdd:PRK13644   98 DLAFGP------ENLCLPPIEIRKRVdRALAEIGLEKYRHRSPK------TLSGGQGQCVALAGILTMEPECLIFDEVTS 165

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 2549828669 423 GVDVGAAAVIRNSLIRLRDDGAAIIVVSEEIDELfEISDRIAVMYRG 469
Cdd:PRK13644  166 MLDPDSGIAVLERIKKLHEKGKTIVYITHNLEEL-HDADRIIVMDRG 211

ABC_FtsE

cd03292

Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ...

253-471

9.16e-08

Pssm-ID: 213259 [Multi-domain] Cd Length: 214 Bit Score: 52.80 E-value: 9.16e-08

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 253 EMRHVSAPGSTRVCGIDNVSLAVRAGEIVGIAGISGNGQARFMAAASGEYLCEADRVLLFNSPVGELdtHARRISGLRyv 332
Cdd:cd03292     2 EFINVTKTYPNGTAALDGINISISAGEFVFLVGPSGAGKSTLLKLIYKEELPTSGTIRVNGQDVSDL--RGRAIPYLR-- 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 333 peQRLGHA-----AVPELSLTANTYLtgdSLVRSGFILRDRARSFANlVIERFHVKTPNAEKAAGsLSGGNLQKFIMGRE 407
Cdd:cd03292    78 --RKIGVVfqdfrLLPDRNVYENVAF---ALEVTGVPPREIRKRVPA-ALELVGLSHKHRALPAE-LSGGEQQRVAIARA 150

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2549828669 408 ILNRPRVLLVHQPTWGVDVGAAAVIRNSLIRLRDDGAAiIVVSEEIDELFE-ISDRIAVMYRGAL 471
Cdd:cd03292   151 IVNSPTILIADEPTGNLDPDTTWEIMNLLKKINKAGTT-VVVATHAKELVDtTRHRVIALERGKL 214

ABC_UvrA

cd03238

ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in ...

3-217

1.33e-07

ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.

Pssm-ID: 213205 [Multi-domain] Cd Length: 176 Bit Score: 51.55 E-value: 1.33e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   3 PRLSLRNITKrypgitandhVSLDIAPGEVLAILGENGAGKSTLMK-IIY--GAARPDEGEISFDGHPLgvetpaqarel 79
Cdd:cd03238     4 SGANVHNLQN----------LDVSIPLNVLVVVTGVSGSGKSTLVNeGLYasGKARLISFLPKFSRNKL----------- 62

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  80 giamvhqhfALFDTLSVTENVALGLSTgisaaeiereirlLGEKYGlevdpasvvmELSMGERQRVEILRALM--TKPKL 157
Cdd:cd03238    63 ---------IFIDQLQFLIDVGLGYLT-------------LGQKLS----------TLSGGELQRVKLASELFsePPGTL 110

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2549828669 158 LILDEPTSVLTPQAVRKLFKTLHQLSSEGVSILFISHKLDEIRElADRCVVL------RAGKVVAS 217
Cdd:cd03238   111 FILDEPSTGLHQQDINQLLEVIKGLIDLGNTVILIEHNLDVLSS-ADWIIDFgpgsgkSGGKVVFS 175

ABC_PstB_phosphate_transporter

cd03260

ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ...

390-471

1.90e-07

Pssm-ID: 213227 [Multi-domain] Cd Length: 227 Bit Score: 51.80 E-value: 1.90e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 390 AAGSLSGGNLQKFIMGREILNRPRVLLVHQPTWGVDVGAAAVIRNSLIRLRDDgAAIIVVSEEIDELFEISDRIAVMYRG 469
Cdd:cd03260   138 HALGLSGGQQQRLCLARALANEPEVLLLDEPTSALDPISTAKIEELIAELKKE-YTIVIVTHNMQQAARVADRTAFLLNG 216


                  ..
gi 2549828669 470 AL 471
Cdd:cd03260   217 RL 218

ABC_RNaseL_inhibitor

cd03222

ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a ...

26-209

1.99e-07

ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins, and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains, which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.

Pssm-ID: 213189 [Multi-domain] Cd Length: 177 Bit Score: 51.03 E-value: 1.99e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  26 DIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGhplgvETPAqarelgiamvhqhfalfdtlsvtenvalgls 105
Cdd:cd03222    21 VVKEGEVIGIVGPNGTGKTTAVKILAGQLIPNGDNDEWDG-----ITPV------------------------------- 64

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 106 tgisaaeiereirllgekygleVDPASVvmELSMGERQRVEILRALMTKPKLLILDEPTSVLTPQAVRKLFKTLHQLSSE 185
Cdd:cd03222    65 ----------------------YKPQYI--DLSGGELQRVAIAAALLRNATFYLFDEPSAYLDIEQRLNAARAIRRLSEE 120

                         170       180
                  ....*....|....*....|....*
gi 2549828669 186 GV-SILFISHKLDEIRELADRCVVL 209
Cdd:cd03222   121 GKkTALVVEHDLAVLDYLSDRIHVF 145

ABC_Carb_Monos_I

cd03216

First domain of the ATP-binding cassette component of monosaccharide transport system; This ...

378-471

2.08e-07

Pssm-ID: 213183 [Multi-domain] Cd Length: 163 Bit Score: 50.50 E-value: 2.08e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 378 ERFHVKTPNAEKAAG-----SLSGGNLQKFIMGREILNRPRVLLVHQPTWGVDVGAAAVIRNSLIRLRDDGAAIIVVSEE 452
Cdd:cd03216    62 KEVSFASPRDARRAGiamvyQLSVGERQMVEIARALARNARLLILDEPTAALTPAEVERLFKVIRRLRAQGVAVIFISHR 141

                          90
                  ....*....|....*....
gi 2549828669 453 IDELFEISDRIAVMYRGAL 471
Cdd:cd03216   142 LDEVFEIADRVTVLRDGRV 160

3a01204

TIGR00955

The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ...

268-476

3.08e-07

The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]

Pssm-ID: 273361 [Multi-domain] Cd Length: 617 Bit Score: 53.13 E-value: 3.08e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 268 IDNVSLAVRAGEIVGIAGISGNGQARFMAAASGEYLCEADR---VLLFNSPVGEldTHARRISGlrYVPEQRLghaAVPe 344
Cdd:TIGR00955  41 LKNVSGVAKPGELLAVMGSSGAGKTTLMNALAFRSPKGVKGsgsVLLNGMPIDA--KEMRAISA--YVQQDDL---FIP- 112

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 345 lSLTANTYLTGDSLVRSG--------------FILRDRARSFANLVIerfhvKTPNAEKaagSLSGGNLQKFIMGREILN 410
Cdd:TIGR00955 113 -TLTVREHLMFQAHLRMPrrvtkkekrervdeVLQALGLRKCANTRI-----GVPGRVK---GLSGGERKRLAFASELLT 183

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2549828669 411 RPRVLLVHQPTWGVDVGAAAVIRNSLIRLRDDGAAIIVV----SEEIDELFeisDRIAVM------YRGALSPAVP 476
Cdd:TIGR00955 184 DPPLLFCDEPTSGLDSFMAYSVVQVLKGLAQKGKTIICTihqpSSELFELF---DKIILMaegrvaYLGSPDQAVP 256

PLN03130

ABC transporter C family member; Provisional

22-178

4.66e-07

ABC transporter C family member; Provisional

Pssm-ID: 215595 [Multi-domain] Cd Length: 1622 Bit Score: 52.82 E-value: 4.66e-07

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   22 HVSLDIAPGEVLAILGENGAGKSTLMKIIYG--AARPDeGEISFDGHplgvetpaqarelgIAMVHQHFALFDTlSVTEN 99
Cdd:PLN03130   635 NINLDVPVGSLVAIVGSTGEGKTSLISAMLGelPPRSD-ASVVIRGT--------------VAYVPQVSWIFNA-TVRDN 698

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  100 VALGLStgISAAEIEREIRLLGEKYGLEVDPASVVME-------LSMGERQRVEILRALMTKPKLLILDEPTSVLTPQAV 172
Cdd:PLN03130   699 ILFGSP--FDPERYERAIDVTALQHDLDLLPGGDLTEigergvnISGGQKQRVSMARAVYSNSDVYIFDDPLSALDAHVG 776


                   ....*.
gi 2549828669  173 RKLFKT 178
Cdd:PLN03130   777 RQVFDK 782

UvrA

COG0178

Excinuclease UvrABC ATPase subunit [Replication, recombination and repair];

137-204

5.05e-07

Excinuclease UvrABC ATPase subunit [Replication, recombination and repair];

Pssm-ID: 439948 [Multi-domain] Cd Length: 941 Bit Score: 52.34 E-value: 5.05e-07

                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2549828669 137 LSMGERQRVEILRALM---TKPKLLILDEPTSVLTPQAVRKLFKTLHQLSSEGVSILFISHKLDEIReLAD 204
Cdd:COG0178   827 LSGGEAQRVKLASELSkrsTGKTLYILDEPTTGLHFHDIRKLLEVLHRLVDKGNTVVVIEHNLDVIK-TAD 896

cbiO

PRK13641

energy-coupling factor transporter ATPase;

256-501

5.11e-07

energy-coupling factor transporter ATPase;

Pssm-ID: 237456 [Multi-domain] Cd Length: 287 Bit Score: 51.37 E-value: 5.11e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 256 HVSAPGST-RVCGIDNVSLAVRAGEIVGIAGISGNGQARFMAAASGEYLCEADRVLLFNSPVgELDTHARRISGLRyvpe 334
Cdd:PRK13641   10 YIYSPGTPmEKKGLDNISFELEEGSFVALVGHTGSGKSTLMQHFNALLKPSSGTITIAGYHI-TPETGNKNLKKLR---- 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 335 QRLGHA-AVPELSLTANTYLTGDSLVRSGF-ILRDRARSFANLVIERFHVKTPNAEKAAGSLSGGNLQKFIMGREILNRP 412
Cdd:PRK13641   85 KKVSLVfQFPEAQLFENTVLKDVEFGPKNFgFSEDEAKEKALKWLKKVGLSEDLISKSPFELSGGQMRRVAIAGVMAYEP 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 413 RVLLVHQPTWGVDVGAAAVIRNSLIRLRDDGAAIIVVSEEIDELFEISDRIAVMYRGAL-SPAVPKPTISIEEvgrWMSG 491
Cdd:PRK13641  165 EILCLDEPAAGLDPEGRKEMMQLFKDYQKAGHTVILVTHNMDDVAEYADDVLVLEHGKLiKHASPKEIFSDKE---WLKK 241

                         250
                  ....*....|
gi 2549828669 492 LWPDSPFTQK 501
Cdd:PRK13641  242 HYLDEPATSR 251

btuD

PRK09536

corrinoid ABC transporter ATPase; Reviewed

261-476

5.76e-07

corrinoid ABC transporter ATPase; Reviewed

Pssm-ID: 236554 [Multi-domain] Cd Length: 402 Bit Score: 51.77 E-value: 5.76e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 261 GSTRVcgIDNVSLAVRAGEIVGIAGISGNGQARFMAAASGEYLCEADRVLLFNSPVGELDthARRISglRYVpeqrlghA 340
Cdd:PRK09536   14 GDTTV--LDGVDLSVREGSLVGLVGPNGAGKTTLLRAINGTLTPTAGTVLVAGDDVEALS--ARAAS--RRV-------A 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 341 AVP-ELSLTANtyLTGDSLVRSG-------FILRDRA-RSFANLVIERFHVkTPNAEKAAGSLSGGNLQKFIMGREILNR 411
Cdd:PRK09536   81 SVPqDTSLSFE--FDVRQVVEMGrtphrsrFDTWTETdRAAVERAMERTGV-AQFADRPVTSLSGGERQRVLLARALAQA 157

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2549828669 412 PRVLLVHQPTWGVDVGAAAVIRNSLIRLRDDGAAIIVVSEEIDELFEISDRIAVMYRGALSPAVP 476
Cdd:PRK09536  158 TPVLLLDEPTASLDINHQVRTLELVRRLVDDGKTAVAAIHDLDLAARYCDELVLLADGRVRAAGP 222

PRK13537

nodulation factor ABC transporter ATP-binding protein NodI;

268-469

5.78e-07

nodulation factor ABC transporter ATP-binding protein NodI;

Pssm-ID: 237420 [Multi-domain] Cd Length: 306 Bit Score: 51.34 E-value: 5.78e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 268 IDNVSLAVRAGEIVGIAGISGNGQARFMAAASGEYLCEADRVLLFNSPVGELDTHARRISGLryVPE-QRLGhaavPELS 346
Cdd:PRK13537   23 VDGLSFHVQRGECFGLLGPNGAGKTTTLRMLLGLTHPDAGSISLCGEPVPSRARHARQRVGV--VPQfDNLD----PDFT 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 347 LTANTYLTGDSLVRSGFILRDRARSFanLVIERFHVKtpnAEKAAGSLSGGNLQKFIMGREILNRPRVLLVHQPTWGVDV 426
Cdd:PRK13537   97 VRENLLVFGRYFGLSAAAARALVPPL--LEFAKLENK---ADAKVGELSGGMKRRLTLARALVNDPDVLVLDEPTTGLDP 171

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 2549828669 427 GAAAVIRNSLIRLRDDGAAIIVVSEEIDELFEISDRIAVMYRG 469
Cdd:PRK13537  172 QARHLMWERLRSLLARGKTILLTTHFMEEAERLCDRLCVIEEG 214

DppD

COG0444

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...

268-469

6.10e-07

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];

Pssm-ID: 440213 [Multi-domain] Cd Length: 320 Bit Score: 51.21 E-value: 6.10e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 268 IDNVSLAVRAGEIVGIAGISGNGQ---AR-FM------AAASGEylceadrVLLFNSPVGELDTHARRisglryvpEQRL 337
Cdd:COG0444    21 VDGVSFDVRRGETLGLVGESGSGKstlARaILgllpppGITSGE-------ILFDGEDLLKLSEKELR--------KIRG 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 338 GHAAV----PELSLtaNTYLT-GDSLVRSGFILRDRARSFA-NLVIERF-HVKTPNAEKAAGS----LSGGNLQKFIMGR 406
Cdd:COG0444    86 REIQMifqdPMTSL--NPVMTvGDQIAEPLRIHGGLSKAEArERAIELLeRVGLPDPERRLDRypheLSGGMRQRVMIAR 163

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2549828669 407 EILNRPRVLLVHQPTWGVDVGAAAVIRNSLIRLRDD-GAAIIVVSEEIDELFEISDRIAVMYRG 469
Cdd:COG0444   164 ALALEPKLLIADEPTTALDVTIQAQILNLLKDLQRElGLAILFITHDLGVVAEIADRVAVMYAG 227

znuC

PRK09544

high-affinity zinc transporter ATPase; Reviewed

261-453

8.07e-07

high-affinity zinc transporter ATPase; Reviewed

Pssm-ID: 181939 [Multi-domain] Cd Length: 251 Bit Score: 50.50 E-value: 8.07e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 261 GSTRVcgIDNVSLAVRAGEIVGIAGISGNGQARFMaaasgeylceadRVLLfnSPVGELDTHARRISGLR--YVPeQRLg 338
Cdd:PRK09544   15 GQRRV--LSDVSLELKPGKILTLLGPNGAGKSTLV------------RVVL--GLVAPDEGVIKRNGKLRigYVP-QKL- 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 339 HAAvPELSLTANTYLTGDSLVRSGFILRDRARSFANLVIERFHVKtpnaekaagsLSGGNLQKFIMGREILNRPRVLLVH 418
Cdd:PRK09544   77 YLD-TTLPLTVNRFLRLRPGTKKEDILPALKRVQAGHLIDAPMQK----------LSGGETQRVLLARALLNRPQLLVLD 145

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 2549828669 419 QPTWGVDVGAAAVIRNSLIRLRDD-GAAIIVVSEEI 453
Cdd:PRK09544  146 EPTQGVDVNGQVALYDLIDQLRRElDCAVLMVSHDL 181

potG

PRK11607

putrescine ABC transporter ATP-binding subunit PotG;

268-469

8.52e-07

putrescine ABC transporter ATP-binding subunit PotG;

Pssm-ID: 183226 [Multi-domain] Cd Length: 377 Bit Score: 50.99 E-value: 8.52e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 268 IDNVSLAVRAGEIVGIAGISGNGQARFMAAASGEYLCEADRVLLFNSPVGELDTHARRISGLRYvpeqrlGHAAVPELSL 347
Cdd:PRK11607   35 VDDVSLTIYKGEIFALLGASGCGKSTLLRMLAGFEQPTAGQIMLDGVDLSHVPPYQRPINMMFQ------SYALFPHMTV 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 348 TANTY--LTGDSLVRSGfiLRDRARSFANLV-IERFHVKTPNaekaagSLSGGNLQKFIMGREILNRPRVLLVHQPTWGV 424
Cdd:PRK11607  109 EQNIAfgLKQDKLPKAE--IASRVNEMLGLVhMQEFAKRKPH------QLSGGQRQRVALARSLAKRPKLLLLDEPMGAL 180

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2549828669 425 DVgaaavirnsliRLRDD------------GAAIIVVSEEIDELFEISDRIAVMYRG 469
Cdd:PRK11607  181 DK-----------KLRDRmqlevvdilervGVTCVMVTHDQEEAMTMAGRIAIMNRG 226

ABC_OpuCA_Osmoprotection

cd03295

ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ...

268-471

9.31e-07

Pssm-ID: 213262 [Multi-domain] Cd Length: 242 Bit Score: 49.99 E-value: 9.31e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 268 IDNVSLAVRAGEIVGIAGISGNGQA-------RFMAAASGEylceadrVLLFNSPVGELD-THARRISGlrYVPeQRLGh 339
Cdd:cd03295    17 VNNLNLEIAKGEFLVLIGPSGSGKTttmkminRLIEPTSGE-------IFIDGEDIREQDpVELRRKIG--YVI-QQIG- 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 340 aAVPELSLTANTYLTGDSLVRSGFILRDRARSFANLV---IERFhvktpnAEKAAGSLSGGNLQKFIMGREILNRPRVLL 416
Cdd:cd03295    86 -LFPHMTVEENIALVPKLLKWPKEKIRERADELLALVgldPAEF------ADRYPHELSGGQQQRVGVARALAADPPLLL 158

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 417 VHQPTWGVDvgaaAVIRNSL----IRL-RDDGAAIIVVSEEIDELFEISDRIAVMYRGAL 471
Cdd:cd03295   159 MDEPFGALD----PITRDQLqeefKRLqQELGKTIVFVTHDIDEAFRLADRIAIMKNGEI 214

PRK14258

phosphate ABC transporter ATP-binding protein; Provisional

268-464

9.53e-07

phosphate ABC transporter ATP-binding protein; Provisional

Pssm-ID: 184593 [Multi-domain] Cd Length: 261 Bit Score: 50.42 E-value: 9.53e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 268 IDNVSLAVRAGEIVGIAGISGNGQARF------MAAASGEYLCEAdRVLLFNSPVGELDTHARRISglRYV----PEQRL 337
Cdd:PRK14258   23 LEGVSMEIYQSKVTAIIGPSGCGKSTFlkclnrMNELESEVRVEG-RVEFFNQNIYERRVNLNRLR--RQVsmvhPKPNL 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 338 GHAAVPElSLTANTYLTG-------DSLVRSGFilrdRARSFANLVIERFHvktpnaeKAAGSLSGGNLQKFIMGREILN 410
Cdd:PRK14258  100 FPMSVYD-NVAYGVKIVGwrpkleiDDIVESAL----KDADLWDEIKHKIH-------KSALDLSGGQQQRLCIARALAV 167

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2549828669 411 RPRVLLVHQPTWGVDVGAAAVIRNSL--IRLRDDgAAIIVVSEEIDELFEISDRIA 464
Cdd:PRK14258  168 KPKVLLMDEPCFGLDPIASMKVESLIqsLRLRSE-LTMVIVSHNLHQVSRLSDFTA 222

Rli1

COG1245

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...

29-196

1.10e-06

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];

Pssm-ID: 440858 [Multi-domain] Cd Length: 592 Bit Score: 51.32 E-value: 1.10e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  29 PGEVLAILGENGAGKSTLMKIIYGAARPDEGEISfdghplgvetpaqaRELGIAMVHQHFA---LFDTLsvtENVALGls 105
Cdd:COG1245    98 KGKVTGILGPNGIGKSTALKILSGELKPNLGDYD--------------EEPSWDEVLKRFRgteLQDYF---KKLANG-- 158

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 106 tGISAA------------------EI-----ER-EIRLLGEKYGLE--VDPAsvVMELSMGERQRVEILRALMTKPKLLI 159
Cdd:COG1245   159 -EIKVAhkpqyvdlipkvfkgtvrELlekvdERgKLDELAEKLGLEniLDRD--ISELSGGELQRVAIAAALLRDADFYF 235

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 2549828669 160 LDEPTSVLTpqaVR---KLFKTLHQLSSEGVSILFISHKL 196
Cdd:COG1245   236 FDEPSSYLD---IYqrlNVARLIRELAEEGKYVLVVEHDL 272

ABC_MalK_N

cd03301

The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ...

394-471

1.20e-06

Pssm-ID: 213268 [Multi-domain] Cd Length: 213 Bit Score: 49.18 E-value: 1.20e-06

                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2549828669 394 LSGGNLQKFIMGREILNRPRVLLVHQPTWGVDVGAAAVIRNSLIRL-RDDGAAIIVVSEEIDELFEISDRIAVMYRGAL 471
Cdd:cd03301   131 LSGGQRQRVALGRAIVREPKVFLMDEPLSNLDAKLRVQMRAELKRLqQRLGTTTIYVTHDQVEAMTMADRIAVMNDGQI 209

ABCC_Protease_Secretion

cd03246

ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ...

268-471

1.28e-06

Pssm-ID: 213213 [Multi-domain] Cd Length: 173 Bit Score: 48.75 E-value: 1.28e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 268 IDNVSLAVRAGEIVGIAGISGNGQARFMAAASGEYLCEADRVLLFNSPVGELDTHARRisglryvpeQRLGhaavpelsl 347
Cdd:cd03246    18 LRNVSFSIEPGESLAIIGPSGSGKSTLARLILGLLRPTSGRVRLDGADISQWDPNELG---------DHVG--------- 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 348 tantYLTGDSLVRSGFIlrdrarsfanlvierfhvktpnaekAAGSLSGGNLQKFIMGREILNRPRVLLVHQPTWGVDVG 427
Cdd:cd03246    80 ----YLPQDDELFSGSI-------------------------AENILSGGQRQRLGLARALYGNPRILVLDEPNSHLDVE 130

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 2549828669 428 AAAVIRNSLIRLRDDGAAIIVVSEEIdELFEISDRIAVMYRGAL 471
Cdd:cd03246   131 GERALNQAIAALKAAGATRIVIAHRP-ETLASADRILVLEDGRV 173

PRK15093

peptide ABC transporter ATP-binding protein SapD;

265-500

1.43e-06

peptide ABC transporter ATP-binding protein SapD;

Pssm-ID: 185049 [Multi-domain] Cd Length: 330 Bit Score: 50.19 E-value: 1.43e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 265 VCGIDNVSLAVRAGEIVGIAGISGNGQARFMAAASG----EYLCEADRvLLFNSpvgeldtharrISGLRYVPEQR---L 337
Cdd:PRK15093   20 VKAVDRVSMTLTEGEIRGLVGESGSGKSLIAKAICGvtkdNWRVTADR-MRFDD-----------IDLLRLSPRERrklV 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 338 GHAAV-----PELSLTANTYLtGDSLVRS--GFILRDRARSFANL----VIERFH-VKTPNAEKAAGS----LSGGNLQK 401
Cdd:PRK15093   88 GHNVSmifqePQSCLDPSERV-GRQLMQNipGWTYKGRWWQRFGWrkrrAIELLHrVGIKDHKDAMRSfpyeLTEGECQK 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 402 FIMGREILNRPRVLLVHQPTWGVDVGAAAVIRNSLIRL-RDDGAAIIVVSEEIDELFEISDRIAVMYRG-ALSPAVPKPT 479
Cdd:PRK15093  167 VMIAIALANQPRLLIADEPTNAMEPTTQAQIFRLLTRLnQNNNTTILLISHDLQMLSQWADKINVLYCGqTVETAPSKEL 246

                         250       260
                  ....*....|....*....|.
gi 2549828669 480 ISIeevgrwmsglwPDSPFTQ 500
Cdd:PRK15093  247 VTT-----------PHHPYTQ 256

PRK14246

phosphate ABC transporter ATP-binding protein; Provisional

391-471

1.67e-06

phosphate ABC transporter ATP-binding protein; Provisional

Pssm-ID: 172734 [Multi-domain] Cd Length: 257 Bit Score: 49.66 E-value: 1.67e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 391 AGSLSGGNLQKFIMGREILNRPRVLLVHQPTWGVDVGAAAVIRNSLIRLRDDgAAIIVVSEEIDELFEISDRIAVMYRGA 470
Cdd:PRK14246  151 ASQLSGGQQQRLTIARALALKPKVLLMDEPTSMIDIVNSQAIEKLITELKNE-IAIVIVSHNPQQVARVADYVAFLYNGE 229


                  .
gi 2549828669 471 L 471
Cdd:PRK14246  230 L 230

PLN03232

ABC transporter C family member; Provisional

2-214

1.72e-06

ABC transporter C family member; Provisional

Pssm-ID: 215640 [Multi-domain] Cd Length: 1495 Bit Score: 51.13 E-value: 1.72e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669    2 TPRLSLRNITKRYPGITAN---DHVSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPdegeisfdghplgVETPAQARE 78
Cdd:PLN03232   612 APAISIKNGYFSWDSKTSKptlSDINLEIPVGSLVAIVGGTGEGKTSLISAMLGELSH-------------AETSSVVIR 678

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   79 LGIAMVHQHFALFDTlSVTENVALG-------LSTGISAAEIEREIRLLGEKYGLEVDPASVvmELSMGERQRVEILRAL 151
Cdd:PLN03232   679 GSVAYVPQVSWIFNA-TVRENILFGsdfeserYWRAIDVTALQHDLDLLPGRDLTEIGERGV--NISGGQKQRVSMARAV 755

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2549828669  152 MTKPKLLILDEPTSVLTPQAVRKLFKTLHQLSSEGVSILFISHKLdEIRELADRCVVLRAGKV 214
Cdd:PLN03232   756 YSNSDIYIFDDPLSALDAHVAHQVFDSCMKDELKGKTRVLVTNQL-HFLPLMDRIILVSEGMI 817

PRK15064

ABC transporter ATP-binding protein; Provisional

37-194

1.91e-06

ABC transporter ATP-binding protein; Provisional

Pssm-ID: 237894 [Multi-domain] Cd Length: 530 Bit Score: 50.28 E-value: 1.91e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  37 GENGAGKSTLMKIIYGAARPDEGEISFD-GHPLGVETPAQarelgiamvhqhFAlFDTLSVTENVALGLST--------- 106
Cdd:PRK15064   34 GANGCGKSTFMKILGGDLEPSAGNVSLDpNERLGKLRQDQ------------FA-FEEFTVLDTVIMGHTElwevkqerd 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 107 ------------GISAAEIE----------REIR----LLGekYGLEVDPASVVM-ELSMGERQRVEILRALMTKPKLLI 159
Cdd:PRK15064  101 riyalpemseedGMKVADLEvkfaemdgytAEARagelLLG--VGIPEEQHYGLMsEVAPGWKLRVLLAQALFSNPDILL 178

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 2549828669 160 LDEPTSVLTPQAVRKLFKTLHQLSSegvSILFISH 194
Cdd:PRK15064  179 LDEPTNNLDINTIRWLEDVLNERNS---TMIIISH 210

PRK14267

phosphate ABC transporter ATP-binding protein; Provisional

391-471

3.12e-06

phosphate ABC transporter ATP-binding protein; Provisional

Pssm-ID: 184596 [Multi-domain] Cd Length: 253 Bit Score: 48.68 E-value: 3.12e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 391 AGSLSGGNLQKFIMGREILNRPRVLLVHQPTWGVDVGAAAVIRNSLIRLRDDgAAIIVVSEEIDELFEISDRIAVMYRGA 470
Cdd:PRK14267  147 PSNLSGGQRQRLVIARALAMKPKILLMDEPTANIDPVGTAKIEELLFELKKE-YTIVLVTHSPAQAARVSDYVAFLYLGK 225


                  .
gi 2549828669 471 L 471
Cdd:PRK14267  226 L 226

phnK

PRK11701

phosphonate C-P lyase system protein PhnK; Provisional

267-469

3.12e-06

phosphonate C-P lyase system protein PhnK; Provisional

Pssm-ID: 183280 [Multi-domain] Cd Length: 258 Bit Score: 48.77 E-value: 3.12e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 267 GIDNVSLAVRAGEIVGIAGISGNGQARFMAAASGE---------Y------------LCEADRVLLFNSPVGELDTHARr 325
Cdd:PRK11701   21 GCRDVSFDLYPGEVLGIVGESGSGKTTLLNALSARlapdagevhYrmrdgqlrdlyaLSEAERRRLLRTEWGFVHQHPR- 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 326 iSGLRyvpeqrlghaavPELSLTANTyltGDSLVRSGFILRDRARSFANLVIERFHVKTPNAEKAAGSLSGGNLQKFIMG 405
Cdd:PRK11701  100 -DGLR------------MQVSAGGNI---GERLMAVGARHYGDIRATAGDWLERVEIDAARIDDLPTTFSGGMQQRLQIA 163

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2549828669 406 REILNRPRVLLVHQPTWGVDVGAAAVIRNSLIRL-RDDGAAIIVVSEEIDELFEISDRIAVMYRG 469
Cdd:PRK11701  164 RNLVTHPRLVFMDEPTGGLDVSVQARLLDLLRGLvRELGLAVVIVTHDLAVARLLAHRLLVMKQG 228

PRK10261

glutathione transporter ATP-binding protein; Provisional

264-500

3.43e-06

glutathione transporter ATP-binding protein; Provisional

Pssm-ID: 182342 [Multi-domain] Cd Length: 623 Bit Score: 49.85 E-value: 3.43e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 264 RVCGIDNVSLAVRAGEIVGIAGISGNGQA-------RFMAAASGEYLCEADRVLLFNSPVGEL----DTHARRISG--LR 330
Cdd:PRK10261   28 KIAAVRNLSFSLQRGETLAIVGESGSGKSvtalalmRLLEQAGGLVQCDKMLLRRRSRQVIELseqsAAQMRHVRGadMA 107

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 331 YVPEQrlghaavPELSLTAnTYLTGDSLVRS-----GFIlRDRARSFANLVIERfhVKTPNAEKAAG----SLSGGNLQK 401
Cdd:PRK10261  108 MIFQE-------PMTSLNP-VFTVGEQIAESirlhqGAS-REEAMVEAKRMLDQ--VRIPEAQTILSryphQLSGGMRQR 176

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 402 FIMGREILNRPRVLLVHQPTWGVDVGAAAVIRNsLIRL--RDDGAAIIVVSEEIDELFEISDRIAVMYRGAlspAVpkPT 479
Cdd:PRK10261  177 VMIAMALSCRPAVLIADEPTTALDVTIQAQILQ-LIKVlqKEMSMGVIFITHDMGVVAEIADRVLVMYQGE---AV--ET 250

                         250       260
                  ....*....|....*....|.
gi 2549828669 480 ISIEEVGRwmsglWPDSPFTQ 500
Cdd:PRK10261  251 GSVEQIFH-----APQHPYTR 266

uvrA

PRK00349

excinuclease ABC subunit UvrA;

137-217

3.77e-06

excinuclease ABC subunit UvrA;

Pssm-ID: 234734 [Multi-domain] Cd Length: 943 Bit Score: 49.69 E-value: 3.77e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 137 LSMGERQRVEILRALMTKPK---LLILDEPTSVLTPQAVRKLFKTLHQLSSEGVSILFISHKLDEIRElADRCVVL---- 209
Cdd:PRK00349  831 LSGGEAQRVKLAKELSKRSTgktLYILDEPTTGLHFEDIRKLLEVLHRLVDKGNTVVVIEHNLDVIKT-ADWIIDLgpeg 909

                          90
                  ....*....|
gi 2549828669 210 --RAGKVVAS 217
Cdd:PRK00349  910 gdGGGEIVAT 919

ABC_NatA_like

cd03267

ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ...

268-471

5.57e-06

Pssm-ID: 213234 [Multi-domain] Cd Length: 236 Bit Score: 47.71 E-value: 5.57e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 268 IDNVSLAVRAGEIVGIAGISGNGQARFMAAASGeylceadrvLLFNSPvGELdtharRISGlrYVP-EQRLGHAAVPELS 346
Cdd:cd03267    37 LKGISFTIEKGEIVGFIGPNGAGKTTTLKILSG---------LLQPTS-GEV-----RVAG--LVPwKRRKKFLRRIGVV 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 347 LTANTYLTGDSLVRSGFIL------------RDRARSFANLV-IERFhVKTPnaekaAGSLSGGNLQKFIMGREILNRPR 413
Cdd:cd03267   100 FGQKTQLWWDLPVIDSFYLlaaiydlpparfKKRLDELSELLdLEEL-LDTP-----VRQLSLGQRMRAEIAAALLHEPE 173

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2549828669 414 VLLVHQPTWGVDVGAAAVIRNSLIRL-RDDGAAIIVVSEEIDELFEISDRIAVMYRGAL 471
Cdd:cd03267   174 ILFLDEPTIGLDVVAQENIRNFLKEYnRERGTTVLLTSHYMKDIEALARRVLVIDKGRL 232

PRK15056

manganese/iron ABC transporter ATP-binding protein;

270-492

7.06e-06

manganese/iron ABC transporter ATP-binding protein;

Pssm-ID: 185016 [Multi-domain] Cd Length: 272 Bit Score: 47.57 E-value: 7.06e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 270 NVSLAVRAGEIVGIAGISGNGQARFMAAASGEYLCEADRVLLFNSPVGEldthARRISGLRYVPEQRLGHAAVPelSLTA 349
Cdd:PRK15056   25 DASFTVPGGSIAALVGVNGSGKSTLFKALMGFVRLASGKISILGQPTRQ----ALQKNLVAYVPQSEEVDWSFP--VLVE 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 350 NTYLTGdSLVRSGFILRDRA--RSFANLVIERFHVkTPNAEKAAGSLSGGNLQKFIMGREILNRPRVLLVHQPTWGVDVG 427
Cdd:PRK15056   99 DVVMMG-RYGHMGWLRRAKKrdRQIVTAALARVDM-VEFRHRQIGELSGGQKKRVFLARAIAQQGQVILLDEPFTGVDVK 176

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2549828669 428 AAAVIRNSLIRLRDDGAAIIVVSEEIDELFEISDrIAVMYRGALSPAVP-KPTISIEEVGRWMSGL 492
Cdd:PRK15056  177 TEARIISLLRELRDEGKTMLVSTHNLGSVTEFCD-YTVMVKGTVLASGPtETTFTAENLELAFSGV 241

PRK14239

phosphate transporter ATP-binding protein; Provisional

390-471

8.14e-06

phosphate transporter ATP-binding protein; Provisional

Pssm-ID: 184585 [Multi-domain] Cd Length: 252 Bit Score: 47.46 E-value: 8.14e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 390 AAGSLSGGNLQKFIMGREILNRPRVLLVHQPTWGVDVGAAAVIRNSLIRLRDDgAAIIVVSEEIDELFEISDRIAVMYRG 469
Cdd:PRK14239  145 SALGLSGGQQQRVCIARVLATSPKIILLDEPTSALDPISAGKIEETLLGLKDD-YTMLLVTRSMQQASRISDRTGFFLDG 223


                  ..
gi 2549828669 470 AL 471
Cdd:PRK14239  224 DL 225

MRP_assoc_pro

TIGR00957

multi drug resistance-associated protein (MRP); This model describes multi drug ...

23-214

8.26e-06

Pssm-ID: 188098 [Multi-domain] Cd Length: 1522 Bit Score: 48.79 E-value: 8.26e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   23 VSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEISFDGhplgvetpaqarelGIAMVHQHfALFDTLSVTENVAL 102
Cdd:TIGR00957  657 ITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVHMKG--------------SVAYVPQQ-AWIQNDSLRENILF 721

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  103 G-------LSTGISAAEIEREIRLLGEKYGLEVDPASVvmELSMGERQRVEILRALMTKPKLLILDEPTSVLTPQAVRKL 175
Cdd:TIGR00957  722 GkalnekyYQQVLEACALLPDLEILPSGDRTEIGEKGV--NLSGGQKQRVSLARAVYSNADIYLFDDPLSAVDAHVGKHI 799

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|...
gi 2549828669  176 FKtlHQLSSEGV----SILFISHKLDEIRELaDRCVVLRAGKV 214
Cdd:TIGR00957  800 FE--HVIGPEGVlknkTRILVTHGISYLPQV-DVIIVMSGGKI 839

PRK13409

ribosome biogenesis/translation initiation ATPase RLI;

29-465

1.00e-05

ribosome biogenesis/translation initiation ATPase RLI;

Pssm-ID: 184037 [Multi-domain] Cd Length: 590 Bit Score: 48.27 E-value: 1.00e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  29 PGEVLAILGENGAGKSTLMKIIYGAARPDEGEisfdghplgVETPAQARElgiamVHQHFA---LFDTLSvtenvalGLS 105
Cdd:PRK13409   98 EGKVTGILGPNGIGKTTAVKILSGELIPNLGD---------YEEEPSWDE-----VLKRFRgteLQNYFK-------KLY 156

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 106 TG-ISAA------------------EI-----EREIRL-LGEKYGLE--VDPAsvVMELSMGERQRVEILRALMTKPKLL 158
Cdd:PRK13409  157 NGeIKVVhkpqyvdlipkvfkgkvrELlkkvdERGKLDeVVERLGLEniLDRD--ISELSGGELQRVAIAAALLRDADFY 234

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 159 ILDEPTSVL-------TPQAVRKLfktlhqlsSEGVSILFISHKLDEIRELADRCVVLRaGK-----VVAsvDPKAE--- 223
Cdd:PRK13409  235 FFDEPTSYLdirqrlnVARLIREL--------AEGKYVLVVEHDLAVLDYLADNVHIAY-GEpgaygVVS--KPKGVrvg 303

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 224 ---------SEENLaRlmIGNDPPTVREGTAKagEVVFEMRHVSAPGSTRvcGIDNVSLAV-----RAGEIVGIAGISGN 289
Cdd:PRK13409  304 ineylkgylPEENM-R--IRPEPIEFEERPPR--DESERETLVEYPDLTK--KLGDFSLEVeggeiYEGEVIGIVGPNGI 376

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 290 GQARFMAAASGEYlcEADRvllfnspvGELDThARRISglrYVPEqrlghaavpelsltantYLTGDSLVRSGFILRDRA 369
Cdd:PRK13409  377 GKTTFAKLLAGVL--KPDE--------GEVDP-ELKIS---YKPQ-----------------YIKPDYDGTVEDLLRSIT 425

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 370 RSFA-----NLVIERFHVKtPNAEKAAGSLSGGNLQKFI----MGRE----ILNRPRVLL-VHQptwgvDVGAAAVIRNs 435
Cdd:PRK13409  426 DDLGssyykSEIIKPLQLE-RLLDKNVKDLSGGELQRVAiaacLSRDadlyLLDEPSAHLdVEQ-----RLAVAKAIRR- 498

                         490       500       510
                  ....*....|....*....|....*....|
gi 2549828669 436 LIRLRDdgAAIIVVSEEIDELFEISDRIAV 465
Cdd:PRK13409  499 IAEERE--ATALVVDHDIYMIDYISDRLMV 526

SunT

COG2274

ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ...

252-469

1.16e-05

ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];

Pssm-ID: 441875 [Multi-domain] Cd Length: 711 Bit Score: 47.91 E-value: 1.16e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 252 FEMRHVS---APGSTRVcgIDNVSLAVRAGEIVGIAGISGNGQARFMAAASGEYLCEADRVLLFNSPVGELDTHARRiSG 328
Cdd:COG2274   474 IELENVSfryPGDSPPV--LDNISLTIKPGERVAIVGRSGSGKSTLLKLLLGLYEPTSGRILIDGIDLRQIDPASLR-RQ 550

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 329 LRYVPeQrlghaavpelsltaNTYLTGDSlVRSGFILRDRARSFANLV-------IERFHVKTPN------AEKAAGsLS 395
Cdd:COG2274   551 IGVVL-Q--------------DVFLFSGT-IRENITLGDPDATDEEIIeaarlagLHDFIEALPMgydtvvGEGGSN-LS 613

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2549828669 396 GGNLQKFIMGREILNRPRVLLVHQPTWGVDVGAAAVIRNSLIRLRdDGAAIIVVSEEiDELFEISDRIAVMYRG 469
Cdd:COG2274   614 GGQRQRLAIARALLRNPRILILDEATSALDAETEAIILENLRRLL-KGRTVIIIAHR-LSTIRLADRIIVLDKG 685

AAA

smart00382

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...

29-205

1.26e-05

Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 45.06 E-value: 1.26e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   29 PGEVLAILGENGAGKSTLMKIIYGAARPDEGEIsfdghplgvetpaqarelgiamvhqhfalfdtlsvtenVALGLSTGI 108
Cdd:smart00382   1 PGEVILIVGPPGSGKTTLARALARELGPPGGGV--------------------------------------IYIDGEDIL 42

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  109 SAAEIEREIRLLGEKYGLEVDpasvvmelsmGERQRVEILRALMTKPKLLILDEPTSVLTPQAVRKLFKTLH------QL 182
Cdd:smart00382  43 EEVLDQLLLIIVGGKKASGSG----------ELRLRLALALARKLKPDVLILDEITSLLDAEQEALLLLLEElrllllLK 112

                          170       180
                   ....*....|....*....|...
gi 2549828669  183 SSEGVSILFISHKLDEIRELADR 205
Cdd:smart00382 113 SEKNLTVILTTNDEKDLGPALLR 135

ABC_Class2

cd03227

ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems ...

24-205

1.65e-05

ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems involved in cellular processes other than transport. These families are characterized by the fact that the ABC subunit is made up of duplicated, fused ABC modules (ABC2). No known transmembrane proteins or domains are associated with these proteins.

Pssm-ID: 213194 [Multi-domain] Cd Length: 162 Bit Score: 45.04 E-value: 1.65e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  24 SLDIAPGEVLAILGENGAGKSTLMK-IIYGaarpdegeisfdghplgvetpaqareLGIAMVHQHFALFdtlsvtenval 102
Cdd:cd03227    15 DVTFGEGSLTIITGPNGSGKSTILDaIGLA--------------------------LGGAQSATRRRSG----------- 57

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 103 GLSTGISAAEiereirllgekyglEVDPASVVMELSMGERQRVE---ILRALMTKPK-LLILDEPTSVLTPQAVRKLFKT 178
Cdd:cd03227    58 VKAGCIVAAV--------------SAELIFTRLQLSGGEKELSAlalILALASLKPRpLYILDEIDRGLDPRDGQALAEA 123

                         170       180
                  ....*....|....*....|....*..
gi 2549828669 179 LHQLSSEGVSILFISHKLdEIRELADR 205
Cdd:cd03227   124 ILEHLVKGAQVIVITHLP-ELAELADK 149

ABC_UvrA_I

cd03270

ATP-binding cassette domain I of the excision repair protein UvrA; Nucleotide excision repair ...

23-217

1.72e-05

ATP-binding cassette domain I of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.

Pssm-ID: 213237 [Multi-domain] Cd Length: 226 Bit Score: 46.10 E-value: 1.72e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  23 VSLDIAPGEVLAILGENGAGKSTL-MKIIYGaarpdEGEISFdghplgVET-PAQARELGIAMVHQHFALFDTLSVTENV 100
Cdd:cd03270    14 VDVDIPRNKLVVITGVSGSGKSSLaFDTIYA-----EGQRRY------VESlSAYARQFLGQMDKPDVDSIEGLSPAIAI 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 101 ALGL------STGISAAEIEREIRLLGEKYGLE-------------VDPASVVMELSMGERQRVEILRALMTKPK--LLI 159
Cdd:cd03270    83 DQKTtsrnprSTVGTVTEIYDYLRLLFARVGIRerlgflvdvglgyLTLSRSAPTLSGGEAQRIRLATQIGSGLTgvLYV 162

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2549828669 160 LDEPTSVLTPQAVRKLFKTLHQLSSEGVSILFISHKLDEIReLADRCVVL------RAGKVVAS 217
Cdd:cd03270   163 LDEPSIGLHPRDNDRLIETLKRLRDLGNTVLVVEHDEDTIR-AADHVIDIgpgagvHGGEIVAQ 225

PRK00635

excinuclease ABC subunit A; Provisional

137-221

2.06e-05

excinuclease ABC subunit A; Provisional

Pssm-ID: 234806 [Multi-domain] Cd Length: 1809 Bit Score: 47.52 E-value: 2.06e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  137 LSMGERQRVEI---LRALMTKPKLLILDEPTSVLTPQAVRKLFKTLHQLSSEGVSILFISHKLdEIRELADRCVVL---- 209
Cdd:PRK00635   810 LSGGEIQRLKLayeLLAPSKKPTLYVLDEPTTGLHTHDIKALIYVLQSLTHQGHTVVIIEHNM-HVVKVADYVLELgpeg 888

                           90
                   ....*....|....
gi 2549828669  210 --RAGKVVASVDPK 221
Cdd:PRK00635   889 gnLGGYLLASCSPE 902

PTZ00243

ABC transporter; Provisional

23-249

2.14e-05

ABC transporter; Provisional

Pssm-ID: 240327 [Multi-domain] Cd Length: 1560 Bit Score: 47.47 E-value: 2.14e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   23 VSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEI----SFdghplgVETPAQARELGiAMVHQHFALFDtlsvtE 98
Cdd:PTZ00243   679 VSVSVPRGKLTVVLGATGSGKSTLLQSLLSQFEISEGRVwaerSI------AYVPQQAWIMN-ATVRGNILFFD-----E 746

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669   99 NVALGLSTGISAAEIEREIRLLGEkyGLEVDPASVVMELSMGERQRVEILRALMTKPKLLILDEPTSVLTPQA----VRK 174
Cdd:PTZ00243   747 EDAARLADAVRVSQLEADLAQLGG--GLETEIGEKGVNLSGGQKARVSLARAVYANRDVYLLDDPLSALDAHVgervVEE 824

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2549828669  175 LFktLHQLSseGVSILFISHKLdEIRELADRCVVLRAGKVVASVDPKAESEENLARLMIGN--DPPTVREGTAKAGE 249
Cdd:PTZ00243   825 CF--LGALA--GKTRVLATHQV-HVVPRADYVVALGDGRVEFSGSSADFMRTSLYATLAAElkENKDSKEGDADAEV 896

uvra

TIGR00630

excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of ...

88-290

2.28e-05

Pssm-ID: 273184 [Multi-domain] Cd Length: 925 Bit Score: 47.32 E-value: 2.28e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  88 FALFDTLSVTENVALglstgiSAAEIEREIRllgEKYGLEVD-------PASVVMELSMGERQRVEILRALMTKPK--LL 158
Cdd:TIGR00630 442 HEFFNQLTLTPEEKK------IAEEVLKEIR---ERLGFLIDvgldylsLSRAAGTLSGGEAQRIRLATQIGSGLTgvLY 512

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 159 ILDEPTSVLTPQAVRKLFKTLHQLSSEGVSILFISHKLDEIRElADRCVVL--RAGK----VVASVDPKAeseenlarLM 232
Cdd:TIGR00630 513 VLDEPSIGLHQRDNRRLINTLKRLRDLGNTLIVVEHDEDTIRA-ADYVIDIgpGAGEhggeVVASGTPEE--------IL 583

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2549828669 233 IGNDPPTvreGTAKAGEV---VFEMRHVSAPGSTRVCG-----IDNVSLAVRAGEIVGIAGISGNG 290
Cdd:TIGR00630 584 ANPDSLT---GQYLSGRKkieVPAERRPGNGKFLTLKGarennLKNITVSIPLGLFTCITGVSGSG 646

PRK14271

phosphate ABC transporter ATP-binding protein; Provisional

394-495

3.60e-05

phosphate ABC transporter ATP-binding protein; Provisional

Pssm-ID: 172759 [Multi-domain] Cd Length: 276 Bit Score: 45.47 E-value: 3.60e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 394 LSGGNLQKFIMGREILNRPRVLLVHQPTWGVDVGAAAVIRnSLIRLRDDGAAIIVVSEEIDELFEISDRIAVMYRGALSP 473
Cdd:PRK14271  164 LSGGQQQLLCLARTLAVNPEVLLLDEPTSALDPTTTEKIE-EFIRSLADRLTVIIVTHNLAQAARISDRAALFFDGRLVE 242

                          90       100
                  ....*....|....*....|....*.
gi 2549828669 474 AVPKPTI----SIEEVGRWMSGLWPD 495
Cdd:PRK14271  243 EGPTEQLfsspKHAETARYVAGLSGD 268

SapD

COG4170

ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];

264-469

4.40e-05

ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];

Pssm-ID: 443330 [Multi-domain] Cd Length: 331 Bit Score: 45.67 E-value: 4.40e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 264 RVCGIDNVSLAVRAGEIVGIAGISGNGQARF----MAAASGEYLCEADRvLLFNSpvgeldtharrISGLRYVPEQR--- 336
Cdd:COG4170    19 RVKAVDRVSLTLNEGEIRGLVGESGSGKSLIakaiCGITKDNWHVTADR-FRWNG-----------IDLLKLSPRERrki 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 337 LGHaavpELSLT---ANTYL-----TGDSLVRS-------GFILRdRARSFANLVIERFH-VKTPNAEKAAGS----LSG 396
Cdd:COG4170    87 IGR----EIAMIfqePSSCLdpsakIGDQLIEAipswtfkGKWWQ-RFKWRKKRAIELLHrVGIKDHKDIMNSypheLTE 161

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2549828669 397 GNLQKFIMGREILNRPRVLLVHQPTWGVDVGAAAVIRNSLIRL-RDDGAAIIVVSEEIDELFEISDRIAVMYRG 469
Cdd:COG4170   162 GECQKVMIAMAIANQPRLLIADEPTNAMESTTQAQIFRLLARLnQLQGTSILLISHDLESISQWADTITVLYCG 235

potA

PRK09452

spermidine/putrescine ABC transporter ATP-binding protein PotA;

394-469

5.14e-05

spermidine/putrescine ABC transporter ATP-binding protein PotA;

Pssm-ID: 236523 [Multi-domain] Cd Length: 375 Bit Score: 45.32 E-value: 5.14e-05

                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2549828669 394 LSGGNLQKFIMGREILNRPRVLLVHQPTWGVDVGAAAVIRNSLIRL-RDDGAAIIVVSEEIDELFEISDRIAVMYRG 469
Cdd:PRK09452  145 LSGGQQQRVAIARAVVNKPKVLLLDESLSALDYKLRKQMQNELKALqRKLGITFVFVTHDQEEALTMSDRIVVMRDG 221

PRK10619

histidine ABC transporter ATP-binding protein HisP;

271-476

8.50e-05

histidine ABC transporter ATP-binding protein HisP;

Pssm-ID: 182592 [Multi-domain] Cd Length: 257 Bit Score: 44.19 E-value: 8.50e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 271 VSLAVRAGEIVGIAGISGNGQARFM-------AAASGEYLCEADRVLLFNSPVGEL---DTHARRISGLR----YVPEQR 336
Cdd:PRK10619   24 VSLQANAGDVISIIGSSGSGKSTFLrcinfleKPSEGSIVVNGQTINLVRDKDGQLkvaDKNQLRLLRTRltmvFQHFNL 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 337 LGHAAVPELSLTANTYLTGDSLVRSgfilRDRARSFANLV--IERFHVKTPNaekaagSLSGGNLQKFIMGREILNRPRV 414
Cdd:PRK10619  104 WSHMTVLENVMEAPIQVLGLSKQEA----RERAVKYLAKVgiDERAQGKYPV------HLSGGQQQRVSIARALAMEPEV 173

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2549828669 415 LLVHQPTWGVDVGAAAVIRNSLIRLRDDGAAIIVVSEEIDELFEISDRIAVMYRGALSPAVP 476
Cdd:PRK10619  174 LLFDEPTSALDPELVGEVLRIMQQLAEEGKTMVVVTHEMGFARHVSSHVIFLHQGKIEEEGA 235

cbiO

PRK13645

energy-coupling factor transporter ATPase;

267-469

9.28e-05

energy-coupling factor transporter ATPase;

Pssm-ID: 184204 [Multi-domain] Cd Length: 289 Bit Score: 44.23 E-value: 9.28e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 267 GIDNVSLAVRAGEIVGIAGISGNGQARFMAAASGEYLCEADRVLL--FNSPVG-----ELDTHARRISGLRYVPEQRLGH 339
Cdd:PRK13645   26 ALNNTSLTFKKNKVTCVIGTTGSGKSTMIQLTNGLIISETGQTIVgdYAIPANlkkikEVKRLRKEIGLVFQFPEYQLFQ 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 340 AAVPELSLTANTYLTGDslvrsgfilRDRARSFANLVIERFHVKTPNAEKAAGSLSGGNLQKFIMGREILNRPRVLLVHQ 419
Cdd:PRK13645  106 ETIEKDIAFGPVNLGEN---------KQEAYKKVPELLKLVQLPEDYVKRSPFELSGGQKRRVALAGIIAMDGNTLVLDE 176

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2549828669 420 PTWGVDVGAAAVIRNSLIRL-RDDGAAIIVVSEEIDELFEISDRIAVMYRG 469
Cdd:PRK13645  177 PTGGLDPKGEEDFINLFERLnKEYKKRIIMVTHNMDQVLRIADEVIVMHEG 227

hmuV

PRK13548

hemin importer ATP-binding subunit; Provisional

268-325

1.13e-04

hemin importer ATP-binding subunit; Provisional

Pssm-ID: 237422 [Multi-domain] Cd Length: 258 Bit Score: 43.99 E-value: 1.13e-04

                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 268 IDNVSLAVRAGEIVGIAGISGNGQARFMAAASGEYLCEADRVLLFNSPVGELDTH--ARR 325
Cdd:PRK13548   18 LDDVSLTLRPGEVVAILGPNGAGKSTLLRALSGELSPDSGEVRLNGRPLADWSPAelARR 77

PRK09984

phosphonate ABC transporter ATP-binding protein;

271-469

1.15e-04

phosphonate ABC transporter ATP-binding protein;

Pssm-ID: 182182 [Multi-domain] Cd Length: 262 Bit Score: 43.85 E-value: 1.15e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 271 VSLAVRAGEIVGIAGISGNGQARFMAAASGeyLCEAD-----RVLLFNSPVGELDTHARRISGLR----YVPEQrlgHAA 341
Cdd:PRK09984   23 VDLNIHHGEMVALLGPSGSGKSTLLRHLSG--LITGDksagsHIELLGRTVQREGRLARDIRKSRantgYIFQQ---FNL 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 342 VPELSLTANTY---LTGDSLVRSGF-----ILRDRA-RSFANLVIERFhvktpnAEKAAGSLSGGNLQKFIMGREILNRP 412
Cdd:PRK09984   98 VNRLSVLENVLigaLGSTPFWRTCFswftrEQKQRAlQALTRVGMVHF------AHQRVSTLSGGQQQRVAIARALMQQA 171

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2549828669 413 RVLLVHQPTWGVDVGAAAVIRNSLIRL-RDDGAAIIVVSEEIDELFEISDRIAVMYRG 469
Cdd:PRK09984  172 KVILADEPIASLDPESARIVMDTLRDInQNDGITVVVTLHQVDYALRYCERIVALRQG 229

cbiO

PRK13638

energy-coupling factor ABC transporter ATP-binding protein;

394-469

1.27e-04

energy-coupling factor ABC transporter ATP-binding protein;

Pssm-ID: 184198 [Multi-domain] Cd Length: 271 Bit Score: 43.84 E-value: 1.27e-04

                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2549828669 394 LSGGNLQKFIMGREILNRPRVLLVHQPTWGVDVGAAAVIRNSLIRLRDDGAAIIVVSEEIDELFEISDRIAVMYRG 469
Cdd:PRK13638  137 LSHGQKKRVAIAGALVLQARYLLLDEPTAGLDPAGRTQMIAIIRRIVAQGNHVIISSHDIDLIYEISDAVYVLRQG 212

PRK13536

nodulation factor ABC transporter ATP-binding protein NodI;

268-484

1.42e-04

nodulation factor ABC transporter ATP-binding protein NodI;

Pssm-ID: 237419 [Multi-domain] Cd Length: 340 Bit Score: 44.05 E-value: 1.42e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 268 IDNVSLAVRAGEIVGIAGISGNGQARFMAAASGEYLCEADRVLLFNSPVGELDTHARRisglryvpeqRLGhaAVPELSL 347
Cdd:PRK13536   57 VNGLSFTVASGECFGLLGPNGAGKSTIARMILGMTSPDAGKITVLGVPVPARARLARA----------RIG--VVPQFDN 124

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 348 TANTYLTGDSLVRSGFILRDRARSFANLV--IERFHVKTPNAEKAAGSLSGGNLQKFIMGREILNRPRVLLVHQPTWGVD 425
Cdd:PRK13536  125 LDLEFTVRENLLVFGRYFGMSTREIEAVIpsLLEFARLESKADARVSDLSGGMKRRLTLARALINDPQLLILDEPTTGLD 204

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2549828669 426 VGAAAVIRNSLIRLRDDGAAIIVVSEEIDELFEISDRIAVMYRGAlSPAVPKPTISIEE 484
Cdd:PRK13536  205 PHARHLIWERLRSLLARGKTILLTTHFMEEAERLCDRLCVLEAGR-KIAEGRPHALIDE 262

PRK10070

proline/glycine betaine ABC transporter ATP-binding protein ProV;

267-469

1.55e-04

proline/glycine betaine ABC transporter ATP-binding protein ProV;

Pssm-ID: 182221 [Multi-domain] Cd Length: 400 Bit Score: 44.25 E-value: 1.55e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 267 GIDNVSLAVRAGEIVGIAGISGNGQARFMAAASGEYLCEADRVLLFNSPVGELDTHARRISGLRYVPEQRLGHAAVPELS 346
Cdd:PRK10070   43 GVKDASLAIEEGEIFVIMGLSGSGKSTMVRLLNRLIEPTRGQVLIDGVDIAKISDAELREVRRKKIAMVFQSFALMPHMT 122

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 347 LTANTYLTGDSLVRSGFILRDRA-RSFANLVIERFHVKTPNaekaagSLSGGNLQKFIMGREILNRPRVLLVHQPTWGVD 425
Cdd:PRK10070  123 VLDNTAFGMELAGINAEERREKAlDALRQVGLENYAHSYPD------ELSGGMRQRVGLARALAINPDILLMDEAFSALD 196

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 2549828669 426 VGAAAVIRNSLIRLR-DDGAAIIVVSEEIDELFEISDRIAVMYRG 469
Cdd:PRK10070  197 PLIRTEMQDELVKLQaKHQRTIVFISHDLDEAMRIGDRIAIMQNG 241

3a01203

TIGR00954

Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, ...

15-195

1.60e-04

Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]

Pssm-ID: 273360 [Multi-domain] Cd Length: 659 Bit Score: 44.35 E-value: 1.60e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  15 PGITANDHV-----SLDIAPGEVLAILGENGAGKSTLMKI------IYGAAR--PDEGEISF-------------DG--H 66
Cdd:TIGR00954 458 PLVTPNGDVlieslSFEVPSGNNLLICGPNGCGKSSLFRIlgelwpVYGGRLtkPAKGKLFYvpqrpymtlgtlrDQiiY 537

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  67 PLGVETpaqarelgiaMVHQHFALFDTLSVTENVALGlstgisaaeiereiRLLGEKYGLEVdPASVVMELSMGERQRVE 146
Cdd:TIGR00954 538 PDSSED----------MKRRGLSDKDLEQILDNVQLT--------------HILEREGGWSA-VQDWMDVLSGGEKQRIA 592

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 2549828669 147 ILRALMTKPKLLILDEPTSVLTPQAVRKLFKTLHQLsseGVSILFISHK 195
Cdd:TIGR00954 593 MARLFYHKPQFAILDECTSAVSVDVEGYMYRLCREF---GITLFSVSHR 638

ABC_RNaseL_inhibitor_domain1

cd03236

The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...

370-467

2.05e-04

Pssm-ID: 213203 [Multi-domain] Cd Length: 255 Bit Score: 43.12 E-value: 2.05e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 370 RSFANLVIERFHVKtPNAEKAAGSLSGGNLQKFIMGREILNRPRVLLVHQPTWGVDVG----AAAVIRnsliRLRDDGAA 445
Cdd:cd03236   117 RGKLDELVDQLELR-HVLDRNIDQLSGGELQRVAIAAALARDADFYFFDEPSSYLDIKqrlnAARLIR----ELAEDDNY 191

                          90       100
                  ....*....|....*....|..
gi 2549828669 446 IIVVSEEIDELFEISDRIAVMY 467
Cdd:cd03236   192 VLVVEHDLAVLDYLSDYIHCLY 213

dppD

PRK11022

dipeptide transporter ATP-binding subunit; Provisional

394-469

2.24e-04

dipeptide transporter ATP-binding subunit; Provisional

Pssm-ID: 182906 [Multi-domain] Cd Length: 326 Bit Score: 43.19 E-value: 2.24e-04

                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2549828669 394 LSGGNLQKFIMGREILNRPRVLLVHQPTWGVDVGAAAVIRNSLIRL-RDDGAAIIVVSEEIDELFEISDRIAVMYRG 469
Cdd:PRK11022  154 LSGGMSQRVMIAMAIACRPKLLIADEPTTALDVTIQAQIIELLLELqQKENMALVLITHDLALVAEAAHKIIVMYAG 230

ABC_MetN_methionine_transporter

cd03258

ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ...

253-471

2.27e-04

Pssm-ID: 213225 [Multi-domain] Cd Length: 233 Bit Score: 42.57 E-value: 2.27e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 253 EMRHVS---APGSTRVCGIDNVSLAVRAGEIVGIAGISGNGQARFMAAASGEYLCEADRVLLFNSPVGELD----THARR 325
Cdd:cd03258     3 ELKNVSkvfGDTGGKVTALKDVSLSVPKGEIFGIIGRSGAGKSTLIRCINGLERPTSGSVLVDGTDLTLLSgkelRKARR 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 326 ISGL----------RYVpeqrLGHAAVP-ELSLTANTYLtgdslvrsgfilRDRARSFANLV-IERFHVKTPnaekaaGS 393
Cdd:cd03258    83 RIGMifqhfnllssRTV----FENVALPlEIAGVPKAEI------------EERVLELLELVgLEDKADAYP------AQ 140

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 394 LSGGNLQKFIMGREILNRPRVLLVHQPTWGVDvgaAAVIRNSLIRLRDD----GAAIIVVSEEIDELFEISDRIAVMYRG 469
Cdd:cd03258   141 LSGGQKQRVGIARALANNPKVLLCDEATSALD---PETTQSILALLRDInrelGLTIVLITHEMEVVKRICDRVAVMEKG 217


                  ..
gi 2549828669 470 AL 471
Cdd:cd03258   218 EV 219

PTZ00265

multidrug resistance protein (mdr1); Provisional

368-465

2.76e-04

multidrug resistance protein (mdr1); Provisional

Pssm-ID: 240339 [Multi-domain] Cd Length: 1466 Bit Score: 43.86 E-value: 2.76e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  368 RARSFAnlVIERFHVKTPNAEKA-----AGSLSGGNLQKFIMGREILNRPRVLLVHQPTWGVDVGAAAVIRNSLIRLRDD 442
Cdd:PTZ00265  1330 RACKFA--AIDEFIESLPNKYDTnvgpyGKSLSGGQKQRIAIARALLREPKILLLDEATSSLDSNSEKLIEKTIVDIKDK 1407

                           90       100
                   ....*....|....*....|....
gi 2549828669  443 G-AAIIVVSEEIDELfEISDRIAV 465
Cdd:PTZ00265  1408 AdKTIITIAHRIASI-KRSDKIVV 1430

cbiO

PRK13637

energy-coupling factor transporter ATPase;

387-469

2.85e-04

energy-coupling factor transporter ATPase;

Pssm-ID: 237455 [Multi-domain] Cd Length: 287 Bit Score: 42.73 E-value: 2.85e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 387 AEKAAGSLSGGNLQKFIMGREILNRPRVLLVHQPTWGVDVGAAAVIRNSLIRLRDD-GAAIIVVSEEIDELFEISDRIAV 465
Cdd:PRK13637  138 KDKSPFELSGGQKRRVAIAGVVAMEPKILILDEPTAGLDPKGRDEILNKIKELHKEyNMTIILVSHSMEDVAKLADRIIV 217


                  ....
gi 2549828669 466 MYRG 469
Cdd:PRK13637  218 MNKG 221

cbiO

PRK13643

energy-coupling factor transporter ATPase;

258-469

3.01e-04

energy-coupling factor transporter ATPase;

Pssm-ID: 184203 [Multi-domain] Cd Length: 288 Bit Score: 42.80 E-value: 3.01e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 258 SAPGSTRvcGIDNVSLAVRAGEIVGIAGISGNGQARFMAAASGeYLCEADRVLLFNSPVGELDTHARRISGLRyvpeQRL 337
Cdd:PRK13643   14 NSPFASR--ALFDIDLEVKKGSYTALIGHTGSGKSTLLQHLNG-LLQPTEGKVTVGDIVVSSTSKQKEIKPVR----KKV 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 338 GHA-AVPELSLTANTYLTGDSLVRSGF-ILRDRARSFANLVIERFHVKTPNAEKAAGSLSGGNLQKFIMGREILNRPRVL 415
Cdd:PRK13643   87 GVVfQFPESQLFEETVLKDVAFGPQNFgIPKEKAEKIAAEKLEMVGLADEFWEKSPFELSGGQMRRVAIAGILAMEPEVL 166

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2549828669 416 LVHQPTWGVDVGAAAVIRNSLIRLRDDGAAIIVVSEEIDELFEISDRIAVMYRG 469
Cdd:PRK13643  167 VLDEPTAGLDPKARIEMMQLFESIHQSGQTVVLVTHLMDDVADYADYVYLLEKG 220

PRK00635

excinuclease ABC subunit A; Provisional

130-207

5.33e-04

excinuclease ABC subunit A; Provisional

Pssm-ID: 234806 [Multi-domain] Cd Length: 1809 Bit Score: 42.89 E-value: 5.33e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  130 PASVVMELSMGERQRVEILRALMTKPK--LLILDEPTSVLTPQAVRKLFKTLHQLSSEGVSILFISHKlDEIRELADRCV 207
Cdd:PRK00635   470 PERALATLSGGEQERTALAKHLGAELIgiTYILDEPSIGLHPQDTHKLINVIKKLRDQGNTVLLVEHD-EQMISLADRII 548

AAA_21

pfam13304

AAA domain, putative AbiEii toxin, Type IV TA system; Several members are annotated as being ...

111-194

6.74e-04

AAA domain, putative AbiEii toxin, Type IV TA system; Several members are annotated as being of the abortive phage resistance system, in which case the family would be acting as the toxin for a type IV toxin-antitoxin resistance system.

Pssm-ID: 433102 [Multi-domain] Cd Length: 303 Bit Score: 41.61 E-value: 6.74e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 111 AEIEREIRLLGEKYGLEVDPAsvvmELSMGERQ---RVEILRALMTKPKLLILDEPTSVLTPQAVRKLFKTLHQLSSEGV 187
Cdd:pfam13304 215 RLRERGLILLENGGGGELPAF----ELSDGTKRllaLLAALLSALPKGGLLLIDEPESGLHPKLLRRLLELLKELSRNGA 290


                  ....*..
gi 2549828669 188 SILFISH 194
Cdd:pfam13304 291 QLILTTH 297

PRK15079

oligopeptide ABC transporter ATP-binding protein OppF; Provisional

395-483

7.79e-04

oligopeptide ABC transporter ATP-binding protein OppF; Provisional

Pssm-ID: 185037 [Multi-domain] Cd Length: 331 Bit Score: 41.62 E-value: 7.79e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 395 SGGNLQKFIMGREILNRPRVLLVHQPTWGVDVGAAAVIRNSLIRL-RDDGAAIIVVSEEIDELFEISDRIAVMYRG---- 469
Cdd:PRK15079  163 SGGQCQRIGIARALILEPKLIICDEPVSALDVSIQAQVVNLLQQLqREMGLSLIFIAHDLAVVKHISDRVLVMYLGhave 242

                          90       100       110
                  ....*....|....*....|....*....|.
gi 2549828669 470 -----------------ALSPAVPKPTISIE 483
Cdd:PRK15079  243 lgtydevyhnplhpytkALMSAVPIPDPDLE 273

PRK13541

cytochrome c biogenesis protein CcmA; Provisional

23-194

7.84e-04

cytochrome c biogenesis protein CcmA; Provisional

Pssm-ID: 184128 [Multi-domain] Cd Length: 195 Bit Score: 40.63 E-value: 7.84e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  23 VSLDIAPGEVLAILGENGAGKSTLMKIIYGAARPDEGEI---------------SFDGHPLGVETpaqarelgiamvhqH 87
Cdd:PRK13541   19 LSITFLPSAITYIKGANGCGKSSLLRMIAGIMQPSSGNIyykncninniakpycTYIGHNLGLKL--------------E 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669  88 FALFDTLSVTENVALGLSTGISAAEIEREIRLLGEKyglevdpasvVMELSMGERQRVEILRALMTKPKLLILDEPTSVL 167
Cdd:PRK13541   85 MTVFENLKFWSEIYNSAETLYAAIHYFKLHDLLDEK----------CYSLSSGMQKIVAIARLIACQSDLWLLDEVETNL 154

                         170       180
                  ....*....|....*....|....*...
gi 2549828669 168 TPQAvRKLFKTLHQL-SSEGVSILFISH 194
Cdd:PRK13541  155 SKEN-RDLLNNLIVMkANSGGIVLLSSH 181

cbiO

PRK13639

cobalt transporter ATP-binding subunit; Provisional

387-487

8.05e-04

cobalt transporter ATP-binding subunit; Provisional

Pssm-ID: 184199 [Multi-domain] Cd Length: 275 Bit Score: 41.22 E-value: 8.05e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2549828669 387 AEKAAGSLSGGNLQKFIMGREILNRPRVLLVHQPTWGVDVGAAAVIRNSLIRLRDDGAAIIVVSEEIDELFEISDRIAVM 466
Cdd:PRK13639  131 ENKPPHHLSGGQKKRVAIAGILAMKPEIIVLDEPTSGLDPMGASQIMKLLYDLNKEGITIIISTHDVDLVPVYADKVYVM 210

                          90       100
                  ....*....|....*....|..
gi 2549828669 467 YRGA-LSPAVPKPTISIEEVGR 487
Cdd:PRK13639  211 SDGKiIKEGTPKEVFSDIETIR 232

COG3950

Predicted ATP-binding protein involved in virulence [General function prediction only];

4-62

1.24e-03

Predicted ATP-binding protein involved in virulence [General function prediction only];

Pssm-ID: 443150 [Multi-domain] Cd Length: 276 Bit Score: 40.75 E-value: 1.24e-03

                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2549828669   4 RLSLRNItKRYpgitANDHVSLDIAPGeVLAILGENGAGKSTLMKIIYGAARPDEGEIS 62
Cdd:COG3950     5 SLTIENF-RGF----EDLEIDFDNPPR-LTVLVGENGSGKTTLLEAIALALSGLLSRLD 57

rim_protein