|
Name |
Accession |
Description |
Interval |
E-value |
| KdpD |
COG2205 |
K+-sensing histidine kinase KdpD [Signal transduction mechanisms]; |
462-679 |
3.01e-56 |
|
K+-sensing histidine kinase KdpD [Signal transduction mechanisms];
Pssm-ID: 441807 [Multi-domain] Cd Length: 239 Bit Score: 191.66 E-value: 3.01e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552383312 462 EEAVREETKSQNMRTELISNVSHDLKTPLTGIKNYVELLQQD-SIDEETRKEYTETLNQYIDRLSTLIEDLFEVSKVNSG 540
Cdd:COG2205 3 EEALEELEELERLKSEFLANVSHELRTPLTSILGAAELLLDEeDLSPEERRELLEIIRESAERLLRLIEDLLDLSRLESG 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552383312 541 NINLDLMELNLIQLIEQTKDECFEVLNSRGLEMIMTSANSEIALMLDGDKTYRIFENLFNNVAKYALPSTRVYIDIIESE 620
Cdd:COG2205 83 KLSLELEPVDLAELLEEAVEELRPLAEEKGIRLELDLPPELPLVYADPELLEQVLANLLDNAIKYSPPGGTITISARREG 162
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2552383312 621 EDVMVEIKN----ISASQMnftsEEIVERFVRGDKSRHESGSGIGLAIVKSYVEAQGGSFKID 679
Cdd:COG2205 163 DGVRISVSDngpgIPEEEL----ERIFERFYRGDNSRGEGGTGLGLAIVKRIVEAHGGTIWVE 221
|
|
| WalK |
COG5002 |
Sensor histidine kinase WalK [Signal transduction mechanisms]; |
378-679 |
2.08e-51 |
|
Sensor histidine kinase WalK [Signal transduction mechanisms];
Pssm-ID: 444026 [Multi-domain] Cd Length: 390 Bit Score: 183.22 E-value: 2.08e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552383312 378 ALINTLVILIMICLWWFGIFLAIIYAVVSYLWVKEKVDKIKADYDVLLVSAENLAKGNFNDEITEDVGVFNSLKDEFRNI 457
Cdd:COG5002 68 LLLLLLLLLLLLALALLLLALLLLLLLLLLLLALLILLLLLALLILLAALLLLLSELLLLLLLLGRLSLRLSALLLGLLL 147
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552383312 458 KTGFEEAVREETKSQNMRTELISNVSHDLKTPLTGIKNYVELLQQDSI-DEETRKEYTETLNQYIDRLSTLIEDLFEVSK 536
Cdd:COG5002 148 LAAVERDITELERLEQMRREFVANVSHELRTPLTSIRGYLELLLDGAAdDPEERREYLEIILEEAERLSRLVNDLLDLSR 227
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552383312 537 VNSGNINLDLMELNLIQLIEQTKDECFEVLNSRGLEMIMTSANSEIALMLDGDKTYRIFENLFNNVAKYALPSTRVYIDI 616
Cdd:COG5002 228 LESGELKLEKEPVDLAELLEEVVEELRPLAEEKGIELELDLPEDPLLVLGDPDRLEQVLTNLLDNAIKYTPEGGTITVSL 307
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2552383312 617 IESEEDVMVEIKN----ISASQMnftsEEIVERFVRGDKS--RHESGSGIGLAIVKSYVEAQGGSFKID 679
Cdd:COG5002 308 REEDDQVRISVRDtgigIPEEDL----PRIFERFYRVDKSrsRETGGTGLGLAIVKHIVEAHGGRIWVE 372
|
|
| BaeS |
COG0642 |
Signal transduction histidine kinase [Signal transduction mechanisms]; |
470-679 |
3.64e-45 |
|
Signal transduction histidine kinase [Signal transduction mechanisms];
Pssm-ID: 440407 [Multi-domain] Cd Length: 328 Bit Score: 164.31 E-value: 3.64e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552383312 470 KSQNMRTELISNVSHDLKTPLTGIKNYVELLQQDSidEETRKEYTETLNQYIDRLSTLIEDLFEVSKVNSGNINLDLMEL 549
Cdd:COG0642 105 EANEAKSRFLANVSHELRTPLTAIRGYLELLLEEL--DEEQREYLETILRSADRLLRLINDLLDLSRLEAGKLELEPEPV 182
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552383312 550 NLIQLIEQTKDECFEVLNSRGLEMIMTSANSEIALMLDGDKTYRIFENLFNNVAKYALPSTRVYIDIIESEEDVMVEIKN 629
Cdd:COG0642 183 DLAELLEEVVELFRPLAEEKGIELELDLPDDLPTVRGDPDRLRQVLLNLLSNAIKYTPEGGTVTVSVRREGDRVRISVED 262
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 2552383312 630 ----ISASQMnftsEEIVERFVRGDKSRHESGSGIGLAIVKSYVEAQGGSFKID 679
Cdd:COG0642 263 tgpgIPPEDL----ERIFEPFFRTDPSRRGGGTGLGLAIVKRIVELHGGTIEVE 312
|
|
| HATPase_VanS-like |
cd16923 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
591-689 |
5.11e-31 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Enterococcus faecium VanS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Enterococcus faecium VanS HK of the VanS-VanR two-component regulatory system (TCS) which activates the transcription of vanH, vanA and vanX vancomycin resistance genes. It also contains Ecoli YedV and PcoS, probable members of YedW-YedV TCS and PcoS-PcoR TCS, repectively. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); most also have a HAMP sensor domain.
Pssm-ID: 340400 [Multi-domain] Cd Length: 102 Bit Score: 116.72 E-value: 5.11e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552383312 591 TYRIFENLFNNVAKYALPSTRVYIDIIESEEDVMVEIKNISASQMNFTSEEIVERFVRGDKSRHESGSGIGLAIVKSYVE 670
Cdd:cd16923 1 LQRVFSNLLSNAIKYSPENTRIYITSFLTDDVVNIMFKNPSSHPLDFKLEKLFERFYRGDNSRNTEGAGLGLSIAKAIIE 80
|
90 100
....*....|....*....|.
gi 2552383312 671 AQGGSFKIDID--GDLFKAII 689
Cdd:cd16923 81 LHGGSASAEYDdnHDLFKVRL 101
|
|
| COG4251 |
COG4251 |
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal ... |
482-675 |
4.05e-23 |
|
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal transduction mechanisms];
Pssm-ID: 443393 [Multi-domain] Cd Length: 503 Bit Score: 103.71 E-value: 4.05e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552383312 482 VSHDLKTPLTGIKNYVELLQQD---SIDEETRkEYTETLNQYIDRLSTLIEDLFEVSKVNSGNINLDLMELNliQLIEQT 558
Cdd:COG4251 289 ASHDLREPLRKISGFSQLLEEDygdKLDEEGR-EYLERIRDAAERMQALIDDLLAYSRVGRQELEFEPVDLN--ELLEEV 365
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552383312 559 KDEcfevlnsrgLEMIMTSANSEIAL----MLDGDKT--YRIFENLFNNVAKYALPST--RVYIDIIESEEDVMVEIK-N 629
Cdd:COG4251 366 LED---------LEPRIEERGAEIEVgplpTVRGDPTllRQVFQNLISNAIKYSRPGEppRIEIGAEREGGEWVFSVRdN 436
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 2552383312 630 ---ISASQmnftSEEIVERFVRGDKSRHESGSGIGLAIVKSYVEAQGGS 675
Cdd:COG4251 437 gigIDPEY----AEKIFEIFQRLHSRDEYEGTGIGLAIVKKIVERHGGR 481
|
|
| NtrY |
COG5000 |
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism ... |
477-679 |
1.82e-20 |
|
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism regulation [Signal transduction mechanisms];
Pssm-ID: 444024 [Multi-domain] Cd Length: 422 Bit Score: 94.64 E-value: 1.82e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552383312 477 ELISNVSHDLKTPLTGIKNYVELLQ-----QDSIDEETRKEYTETLNQYIDRLSTLIEDLFEVSKVnsgnINLDLMELNL 551
Cdd:COG5000 203 ELARRIAHEIKNPLTPIQLSAERLRrkladKLEEDREDLERALDTIIRQVDRLKRIVDEFLDFARL----PEPQLEPVDL 278
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552383312 552 IQLIEQTKDECFEVLNSRGLEMIMTSANSEIALMLDGDKTYRIFENLFNNvAKYALPST-RVYIDIIESEEDVMVEIKN- 629
Cdd:COG5000 279 NELLREVLALYEPALKEKDIRLELDLDPDLPEVLADRDQLEQVLINLLKN-AIEAIEEGgEIEVSTRREDGRVRIEVSDn 357
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 2552383312 630 ---ISASQMnftsEEIVERFVrgdkSRHESGSGIGLAIVKSYVEAQGGSFKID 679
Cdd:COG5000 358 gpgIPEEVL----ERIFEPFF----TTKPKGTGLGLAIVKKIVEEHGGTIELE 402
|
|
| cztS_silS_copS |
TIGR01386 |
heavy metal sensor kinase; Members of this family contain a sensor histidine kinase domain ... |
480-675 |
2.90e-19 |
|
heavy metal sensor kinase; Members of this family contain a sensor histidine kinase domain (pfam00512) and a domain found in bacterial signal proteins (pfam00672). This group is separated phylogenetically from related proteins with similar architecture and contains a number of proteins associated with heavy metal resistance efflux systems for copper, silver, cadmium, and/or zinc.
Pssm-ID: 273593 [Multi-domain] Cd Length: 457 Bit Score: 91.30 E-value: 2.90e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552383312 480 SNVSHDLKTPLTGI--KNYVELLQqdsidEETRKEYTETLNQYID---RLSTLIEDLFEVSKVNSGNINLDLMELNLIQL 554
Cdd:TIGR01386 246 ADLAHELRTPLTNLlgQTQVALSQ-----PRTGEEYREVLESNLEeleRLSRMVSDMLFLARADNGQLALERVRLDLAAE 320
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552383312 555 IEQTKdECFEVL-NSRGLEMIMtsaNSEIALMLDGDKTYRIFENLFNNVAKYALPSTRVYIDIIESEEDVMVEIKNISAS 633
Cdd:TIGR01386 321 LAKVA-EYFEPLaEERGVRIRV---EGEGLVRGDPQMFRRAISNLLSNALRHTPDGGTITVRIERRSDEVRVSVSNPGPG 396
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 2552383312 634 QMNFTSEEIVERFVRGDKSRHES--GSGIGLAIVKSYVEAQGGS 675
Cdd:TIGR01386 397 IPPEHLSRLFDRFYRVDPARSNSgeGTGLGLAIVRSIMEAHGGR 440
|
|
| NtrB |
COG3852 |
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms]; |
453-681 |
5.72e-18 |
|
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms];
Pssm-ID: 443061 [Multi-domain] Cd Length: 361 Bit Score: 86.05 E-value: 5.72e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552383312 453 EFRNIkTGFEEAVREETKSQNMRT--ELISNVSHDLKTPLTGIKNYVELLQQDSIDEETRkEYTETLNQYIDRLSTLIED 530
Cdd:COG3852 112 VLRDI-TERKRLERELRRAEKLAAvgELAAGLAHEIRNPLTGIRGAAQLLERELPDDELR-EYTQLIIEEADRLNNLVDR 189
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552383312 531 LFEVSKVNSgninLDLMELNLIQLIEQTkdecfevlnsrgLEMIMTSANSEIAL-----------MLDGDKTYRIFENLF 599
Cdd:COG3852 190 LLSFSRPRP----PEREPVNLHEVLERV------------LELLRAEAPKNIRIvrdydpslpevLGDPDQLIQVLLNLV 253
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552383312 600 NNvAKYALP-------STR----VYIDIIESEEDVMVEIKN----IsasqmnftSEEIVER----FVrgdkSRHESGSGI 660
Cdd:COG3852 254 RN-AAEAMPeggtitiRTRverqVTLGGLRPRLYVRIEVIDngpgI--------PEEILDRifepFF----TTKEKGTGL 320
|
250 260
....*....|....*....|.
gi 2552383312 661 GLAIVKSYVEAQGGsfKIDID 681
Cdd:COG3852 321 GLAIVQKIVEQHGG--TIEVE 339
|
|
| PRK10549 |
PRK10549 |
two-component system sensor histidine kinase BaeS; |
431-675 |
6.79e-18 |
|
two-component system sensor histidine kinase BaeS;
Pssm-ID: 182539 [Multi-domain] Cd Length: 466 Bit Score: 87.00 E-value: 6.79e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552383312 431 LAKGNFNDEITEdvgvfnSLKDEFRNIKTGFEEAVREETKSQNMRTELISNVSHDLKTPLTGIKNYVELLqQDSIdeetR 510
Cdd:PRK10549 202 LAAGDFTTRVTP------TSRDELGRLAQDFNQLASTLEKNEQMRRDFMADISHELRTPLAVLRGELEAI-QDGV----R 270
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552383312 511 KEYTETLNQY---IDRLSTLIEDLFEVSKVNSGNINLDLMELNLIQLIEQTKDECFEVLNSRGLEmIMTSANSEIALMLD 587
Cdd:PRK10549 271 KFTPESVASLqaeVGTLTKLVDDLHQLSLSDEGALAYRKTPVDLVPLLEVAGGAFRERFASRGLT-LQLSLPDSATVFGD 349
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552383312 588 GDKTYRIFENLFNNVAKYALPSTRVYIDIIESEEDVMVEIKN----ISASQMnftsEEIVERFVRGDKSRHES--GSGIG 661
Cdd:PRK10549 350 PDRLMQLFNNLLENSLRYTDSGGSLHISAEQRDKTLRLTFADsapgVSDEQL----QKLFERFYRTEGSRNRAsgGSGLG 425
|
250
....*....|....
gi 2552383312 662 LAIVKSYVEAQGGS 675
Cdd:PRK10549 426 LAICLNIVEAHNGR 439
|
|
| HisKA |
cd00082 |
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed ... |
472-536 |
2.05e-17 |
|
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via trans-autophosphorylation by the catalytic domain of the histidine kinase. They subsequently transfer the phosphoryl group to the Asp acceptor residue of a response regulator protein. Two-component signalling systems, consisting of a histidine protein kinase that senses a signal input and a response regulator that mediates the output, are ancient and evolutionarily conserved signaling mechanisms in prokaryotes and eukaryotes.
Pssm-ID: 119399 [Multi-domain] Cd Length: 65 Bit Score: 76.87 E-value: 2.05e-17
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2552383312 472 QNMRTELISNVSHDLKTPLTGIKNYVELLQQDSIDEETRKEYTETLNQYIDRLSTLIEDLFEVSK 536
Cdd:cd00082 1 LQAKGEFLANVSHELRTPLTAIRGALELLEEELLDDEEQREYLERIREEAERLLRLINDLLDLSR 65
|
|
| PRK10490 |
PRK10490 |
sensor protein KdpD; Provisional |
462-674 |
5.89e-17 |
|
sensor protein KdpD; Provisional
Pssm-ID: 236701 [Multi-domain] Cd Length: 895 Bit Score: 85.47 E-value: 5.89e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552383312 462 EEAVREETKSQNMRTELISNVSHDLKTPLTGIKNYVELLQQDSIDEETRkeYTETLNQYIDR-LST--LIEDLFEVSKVN 538
Cdd:PRK10490 651 EEQARLASEREQLRNALLAALSHDLRTPLTVLFGQAEILTLDLASEGSP--HARQASEIRQQvLNTtrLVNNLLDMARIQ 728
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552383312 539 SGNINLDLMELNLIQLIEQTKDECFEVLNSRGLEMimtSANSEIALM-LDGDKTYRIFENLFNNVAKYALPSTRVYIDII 617
Cdd:PRK10490 729 SGGFNLRKEWLTLEEVVGSALQMLEPGLSGHPINL---SLPEPLTLIhVDGPLFERVLINLLENAVKYAGAQAEIGIDAH 805
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2552383312 618 ESEEDVMVEIKN----ISASQMNFtseeIVERFVRGDKSRHESGSGIGLAIVKSYVEAQGG 674
Cdd:PRK10490 806 VEGERLQLDVWDngpgIPPGQEQL----IFDKFARGNKESAIPGVGLGLAICRAIVEVHGG 862
|
|
| HisKA |
pfam00512 |
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine ... |
474-540 |
6.98e-17 |
|
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine kinases.
Pssm-ID: 459839 [Multi-domain] Cd Length: 66 Bit Score: 75.33 E-value: 6.98e-17
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2552383312 474 MRTELISNVSHDLKTPLTGIKNYVELLQQDSIDEETRkEYTETLNQYIDRLSTLIEDLFEVSKVNSG 540
Cdd:pfam00512 1 AKSEFLANLSHELRTPLTAIRGYLELLRDEKLDEEQR-EYLETILRSAERLLRLINDLLDLSRIEAG 66
|
|
| HisKA |
smart00388 |
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine ... |
474-540 |
3.49e-16 |
|
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine kinases.
Pssm-ID: 214644 [Multi-domain] Cd Length: 66 Bit Score: 73.37 E-value: 3.49e-16
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2552383312 474 MRTELISNVSHDLKTPLTGIKNYVELLQQDSIDEETRkEYTETLNQYIDRLSTLIEDLFEVSKVNSG 540
Cdd:smart00388 1 AKREFLANLSHELRTPLTAIRGYLELLLDTELSEEQR-EYLETILREAERLLRLINDLLDLSRIEAG 66
|
|
| COG4191 |
COG4191 |
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal ... |
452-679 |
1.57e-15 |
|
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal transduction mechanisms];
Pssm-ID: 443345 [Multi-domain] Cd Length: 361 Bit Score: 78.69 E-value: 1.57e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552383312 452 DEFRNIKTGFEEAVREETKSQNMRTELI------------SNVSHDLKTPLTGIKNYVELLQ---QDSIDEETRKEYTET 516
Cdd:COG4191 107 AELEELERDITELERAEEELRELQEQLVqseklaalgelaAGIAHEINNPLAAILGNAELLRrrlEDEPDPEELREALER 186
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552383312 517 LNQYIDRLSTLIEDLFEVSKVNSgninLDLMELNLIQLIEQTKDECFEVLNSRGLEMIMTSANSEIALMLDGDKTYRIFE 596
Cdd:COG4191 187 ILEGAERAAEIVRSLRAFSRRDE----EEREPVDLNELIDEALELLRPRLKARGIEVELDLPPDLPPVLGDPGQLEQVLL 262
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552383312 597 NLFNNvAKYALPST---RVYIDIIESEEDVMVEIKN----ISASQMN------FTSeeiverfvrgdKSRHEsGSGIGLA 663
Cdd:COG4191 263 NLLIN-AIDAMEEGeggRITISTRREGDYVVISVRDngpgIPPEVLErifepfFTT-----------KPVGK-GTGLGLS 329
|
250
....*....|....*.
gi 2552383312 664 IVKSYVEAQGGSFKID 679
Cdd:COG4191 330 ISYGIVEKHGGRIEVE 345
|
|
| PRK10755 |
PRK10755 |
two-component system sensor histidine kinase PmrB; |
427-696 |
1.72e-14 |
|
two-component system sensor histidine kinase PmrB;
Pssm-ID: 236751 [Multi-domain] Cd Length: 356 Bit Score: 75.39 E-value: 1.72e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552383312 427 SAENLAKGNFNDEITEDVGVFNSLKDEFrniktgfeeaVREETKSQNMRtELISNVSHDLKTPLTGIKNYVELLQQDSID 506
Cdd:PRK10755 100 TADNLTPIAIHSSTLEIEAVTSALNQLV----------SRLTSTLDQER-LFTADVAHELRTPLAGIRLHLELLEKQHHI 168
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552383312 507 EetrkeyTETLNQYIDRLSTLIEDLFEVSKVN----SGNI-NLDLMElnliQLIEQTKDECFEVLNSRGLEMIMTSANSE 581
Cdd:PRK10755 169 D------VAPLIARLDQMMHTVEQLLQLARAGqsfsSGHYqTVKLLE----DVILPSQDELSEMLEQRQQTLLLPESAAD 238
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552383312 582 IalMLDGDKTY--RIFENLFNNVAKYALPSTRVYIDIIESEEDVMVEIKN----ISASQMnftsEEIVERFVRGDkSRHe 655
Cdd:PRK10755 239 I--TVQGDATLlrLLLRNLVENAHRYSPEGSTITIKLSQEDGGAVLAVEDegpgIDESKC----GELSKAFVRMD-SRY- 310
|
250 260 270 280
....*....|....*....|....*....|....*....|...
gi 2552383312 656 SGSGIGLAIVKSYVEAQGGSFKID--IDGDLFKAIIVFRKNTN 696
Cdd:PRK10755 311 GGIGLGLSIVSRITQLHHGQFFLQnrQERSGTRAWVWLPKAQN 353
|
|
| phoR |
PRK11006 |
phosphate regulon sensor histidine kinase PhoR; |
472-666 |
1.82e-14 |
|
phosphate regulon sensor histidine kinase PhoR;
Pssm-ID: 182895 [Multi-domain] Cd Length: 430 Bit Score: 76.20 E-value: 1.82e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552383312 472 QNMRTELISNVSHDLKTPLTGIKNYVELLQQDSIDEETRKEYTETLNQYIDRLSTLIEDLFEVSKVNSG---NIN----- 543
Cdd:PRK11006 201 EGARRNFFANVSHELRTPLTVLQGYLEMMQDQPLEGALREKALHTMREQTQRMEGLVKQLLTLSKIEAAptiDLNekvdv 280
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552383312 544 ---LDLMELNLIQLIEQTKDECFEV---LNSRGLEMIMTSANSeialmldgdktyrifeNLFNNVAKYALPSTRVYIDII 617
Cdd:PRK11006 281 pmmLRVLEREAQTLSQGKHTITFEVdnsLKVFGNEDQLRSAIS----------------NLVYNAVNHTPEGTHITVRWQ 344
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 2552383312 618 ESEEDVMVEIKN----ISASQMnftsEEIVERFVRGDK--SRHESGSGIGLAIVK 666
Cdd:PRK11006 345 RVPQGAEFSVEDngpgIAPEHI----PRLTERFYRVDKarSRQTGGSGLGLAIVK 395
|
|
| PRK10604 |
PRK10604 |
sensor protein RstB; Provisional |
475-679 |
5.42e-14 |
|
sensor protein RstB; Provisional
Pssm-ID: 236724 [Multi-domain] Cd Length: 433 Bit Score: 74.64 E-value: 5.42e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552383312 475 RTELISNVSHDLKTPLTGIKNYVELLQQDSIDEEtrkeytETLNQYIDRLSTLIEDLFEVSKVNSGNINLDLMELNLIQL 554
Cdd:PRK10604 212 KKQLIDGIAHELRTPLVRLRYRLEMSDNLSAAES------QALNRDIGQLEALIEELLTYARLDRPQNELHLSEPDLPAW 285
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552383312 555 IeQTKDECFEVLNSrGLEMIMTSANSEIALMLDGDKTYRIFENLFNNVAKYAlpSTRVYIDIIESEEDVMVEIKN----I 630
Cdd:PRK10604 286 L-STHLADIQAVTP-EKTVRLDTPHQGDYGALDMRLMERVLDNLLNNALRYA--HSRVRVSLLLDGNQACLIVEDdgpgI 361
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 2552383312 631 SASQmnftSEEIVERFVRGDKSRHES--GSGIGLAIVKSYVEAQGGSFKID 679
Cdd:PRK10604 362 PPEE----RERVFEPFVRLDPSRDRAtgGCGLGLAIVHSIALAMGGSVNCD 408
|
|
| PRK15347 |
PRK15347 |
two component system sensor kinase; |
435-679 |
1.03e-13 |
|
two component system sensor kinase;
Pssm-ID: 237951 [Multi-domain] Cd Length: 921 Bit Score: 74.68 E-value: 1.03e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552383312 435 NFNDEITEDVGVFNSL----KDEFRNIKTGFEEAVRE--ETKSQ----NMR-TELISNVSHDLKTPLTGIKNYVELLQQD 503
Cdd:PRK15347 347 NRLDELGSIAKAYNQLldtlNEQYDTLENKVAERTQAlaEAKQRaeqaNKRkSEHLTTISHEIRTPLNGVLGALELLQNT 426
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552383312 504 SIDEETRkEYTETLNQYIDRLSTLIEDLFEVSKVNSGNINLDLMELNLIQLIEQTkdecFEVLNSRGLEMIMT-----SA 578
Cdd:PRK15347 427 PLTAEQM-DLADTARQCTLSLLAIINNLLDFSRIESGQMTLSLEETALLPLLDQA----MLTIQGPAQSKSLTlrtfvGA 501
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552383312 579 NSEIALMLDGDKTYRIFENLFNNVAKYAlPSTRVYIdIIESEEDVM----------VEIKNISasqmnftseEIVERFVR 648
Cdd:PRK15347 502 HVPLYLHLDSLRLRQILVNLLGNAVKFT-ETGGIRL-RVKRHEQQLcftvedtgcgIDIQQQQ---------QIFTPFYQ 570
|
250 260 270
....*....|....*....|....*....|.
gi 2552383312 649 GDKsrHESGSGIGLAIVKSYVEAQGGSFKID 679
Cdd:PRK15347 571 ADT--HSQGTGLGLTIASSLAKMMGGELTLF 599
|
|
| PRK11360 |
PRK11360 |
two-component system sensor histidine kinase AtoS; |
466-674 |
2.32e-12 |
|
two-component system sensor histidine kinase AtoS;
Pssm-ID: 236901 [Multi-domain] Cd Length: 607 Bit Score: 70.00 E-value: 2.32e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552383312 466 REETKSQNMRTE-------LISNVSHDLKTPLTGIKNYVELLQQDSIDEETRKeYTETLNQYIDRLSTLIEDLFEVSK-- 536
Cdd:PRK11360 374 RKRLQRRVARQErlaalgeLVAGVAHEIRNPLTAIRGYVQIWRQQTSDPPSQE-YLSVVLREVDRLNKVIDQLLEFSRpr 452
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552383312 537 ---VNSGNINlDLME--LNLIQLIEQTKDECFEvlnsrglemimTSANSEI-ALMLDGDKTYRIFENLFNNvAKYALPST 610
Cdd:PRK11360 453 esqWQPVSLN-ALVEevLQLFQTAGVQARVDFE-----------TELDNELpPIWADPELLKQVLLNILIN-AVQAISAR 519
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552383312 611 -RVYIDI-IESEEDVMVEIKN----ISASQMnftsEEIVERFVrgdkSRHESGSGIGLAIVKSYVEAQGG 674
Cdd:PRK11360 520 gKIRIRTwQYSDGQVAVSIEDngcgIDPELL----KKIFDPFF----TTKAKGTGLGLALSQRIINAHGG 581
|
|
| PRK09959 |
PRK09959 |
acid-sensing system histidine kinase EvgS; |
453-679 |
3.93e-12 |
|
acid-sensing system histidine kinase EvgS;
Pssm-ID: 182169 [Multi-domain] Cd Length: 1197 Bit Score: 69.76 E-value: 3.93e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552383312 453 EFRNIKTGFEEAVREETKSQNMRTELISNVSHDLKTPLTGIKNYVELLQQDSIDEETRKEYTETLNQYIDRLSTLIEDLF 532
Cdd:PRK09959 690 ETRDLIHALEVERNKAINATVAKSQFLATMSHEIRTPISSIMGFLELLSGSGLSKEQRVEAISLAYATGQSLLGLIGEIL 769
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552383312 533 EVSKVNSGNINLDLMELNLIQLIEQTKDECFEVLNSRGLEMIMTSANSEIALM-LDGDKTYRIFENLFNNVAKY----AL 607
Cdd:PRK09959 770 DVDKIESGNYQLQPQWVDIPTLVQNTCHSFGAIAASKSIALSCSSTFPDHYLVkIDPQAFKQVLSNLLSNALKFttegAV 849
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2552383312 608 PSTRVYIDIIESEEDVMVEIKNISASQMNFTSEEIVERFVRGDKSRHESGSGIGLAIVKSYVEAQGGSFKID 679
Cdd:PRK09959 850 KITTSLGHIDDNHAVIKMTIMDSGSGLSQEEQQQLFKRYSQTSAGRQQTGSGLGLMICKELIKNMQGDLSLE 921
|
|
| HATPase_c |
smart00387 |
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases. |
592-679 |
6.18e-12 |
|
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
Pssm-ID: 214643 [Multi-domain] Cd Length: 111 Bit Score: 62.67 E-value: 6.18e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552383312 592 YRIFENLFNNVAKYALPSTRVYIDIIESEEDVMVEIKN----ISASQMnftsEEIVERFVRGDK-SRHESGSGIGLAIVK 666
Cdd:smart00387 7 RQVLSNLLDNAIKYTPEGGRITVTLERDGDHVEITVEDngpgIPPEDL----EKIFEPFFRTDKrSRKIGGTGLGLSIVK 82
|
90
....*....|...
gi 2552383312 667 SYVEAQGGSFKID 679
Cdd:smart00387 83 KLVELHGGEISVE 95
|
|
| envZ |
PRK09467 |
osmolarity sensor protein; Provisional |
475-678 |
1.39e-11 |
|
osmolarity sensor protein; Provisional
Pssm-ID: 236531 [Multi-domain] Cd Length: 435 Bit Score: 67.24 E-value: 1.39e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552383312 475 RTELISNVSHDLKTPLTGIKNYVELLQQ------DSIDEETrKEYTETLNQYIDRLSTLIEDLFEVSKVNSgninldlme 548
Cdd:PRK09467 229 RTLLMAGVSHDLRTPLTRIRLATEMMSEedgylaESINKDI-EECNAIIEQFIDYLRTGQEMPMEMADLNA--------- 298
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552383312 549 lnLIQlieqtkdecfEVLNSR-GLEMIMTSANSEIALMLDGD----KtyRIFENLFNNVAKYAlpSTRVYIDIIESEEDV 623
Cdd:PRK09467 299 --LLG----------EVIAAEsGYEREIETALQPGPIEVPMNpiaiK--RALANLVVNAARYG--NGWIKVSSGTEGKRA 362
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 2552383312 624 MVEIKN----ISASQMnftsEEIVERFVRGDKSRHESGSGIGLAIVKSYVEAQGGSFKI 678
Cdd:PRK09467 363 WFQVEDdgpgIPPEQL----KHLFQPFTRGDSARGSSGTGLGLAIVKRIVDQHNGKVEL 417
|
|
| PRK09835 |
PRK09835 |
Cu(+)/Ag(+) sensor histidine kinase; |
480-690 |
2.23e-11 |
|
Cu(+)/Ag(+) sensor histidine kinase;
Pssm-ID: 182101 [Multi-domain] Cd Length: 482 Bit Score: 66.72 E-value: 2.23e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552383312 480 SNVSHDLKTPLTGIKNYVEL-LQQDSIDEETRKEYTETLNQYiDRLSTLIEDLFEVSKVNSGNINLDLMELNLIQLIEQT 558
Cdd:PRK09835 267 ADIAHEIRTPITNLITQTEIaLSQSRSQKELEDVLYSNLEEL-TRMAKMVSDMLFLAQADNNQLIPEKKMLDLADEVGKV 345
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552383312 559 KDeCFEVLnsrglemimtSANSEIALMLDGDKTY---------RIFENLFNNVAKYALPSTRVYIDIIESEEDVMVEIKN 629
Cdd:PRK09835 346 FD-FFEAW----------AEERGVELRFVGDPCQvagdplmlrRAISNLLSNALRYTPAGEAITVRCQEVDHQVQLVVEN 414
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2552383312 630 ----ISASQMnftsEEIVERFVRGDKSRHESG--SGIGLAIVKSYVEAQGGSFKIDIDGDLFKAIIV 690
Cdd:PRK09835 415 pgtpIAPEHL----PRLFDRFYRVDPSRQRKGegSGIGLAIVKSIVVAHKGTVAVTSDARGTRFVIS 477
|
|
| PRK10364 |
PRK10364 |
two-component system sensor histidine kinase ZraS; |
462-679 |
1.02e-10 |
|
two-component system sensor histidine kinase ZraS;
Pssm-ID: 236674 [Multi-domain] Cd Length: 457 Bit Score: 64.42 E-value: 1.02e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552383312 462 EEAVREETKSQNMRTeLISNVSHDLKTPLTGIKNYVELLQQDSIDEETRKEYTETLNQYIDRLSTLIEDLFEVSK----- 536
Cdd:PRK10364 225 QDEMKRKEKLVALGH-LAAGVAHEIRNPLSSIKGLAKYFAERAPAGGEAHQLAQVMAKEADRLNRVVSELLELVKpthla 303
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552383312 537 VNSGNINlDLMELNLiQLIEQTKdecfevlNSRGLEMIMTSANSEIALMLDGDKTYRIFENLFNNvAKYALPSTRVyIDI 616
Cdd:PRK10364 304 LQAVDLN-DLINHSL-QLVSQDA-------NSREIQLRFTANDTLPEIQADPDRLTQVLLNLYLN-AIQAIGQHGV-ISV 372
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2552383312 617 IESEEDVMVEI------KNISASQMN------FTSEEiverfvrgdksrheSGSGIGLAIVKSYVEAQGGSFKID 679
Cdd:PRK10364 373 TASESGAGVKIsvtdsgKGIAADQLEaiftpyFTTKA--------------EGTGLGLAVVHNIVEQHGGTIQVA 433
|
|
| HATPase_c |
pfam02518 |
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the ... |
587-679 |
1.77e-10 |
|
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.
Pssm-ID: 460579 [Multi-domain] Cd Length: 109 Bit Score: 58.53 E-value: 1.77e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552383312 587 DGDKTYRIFENLFNNVAKYALPSTRVYIdIIESEEDVMVEIKN----ISASQMnftsEEIVERFVRGDKSRHEsGSGIGL 662
Cdd:pfam02518 2 DELRLRQVLSNLLDNALKHAAKAGEITV-TLSEGGELTLTVEDngigIPPEDL----PRIFEPFSTADKRGGG-GTGLGL 75
|
90
....*....|....*..
gi 2552383312 663 AIVKSYVEAQGGSFKID 679
Cdd:pfam02518 76 SIVRKLVELLGGTITVE 92
|
|
| PRK10337 |
PRK10337 |
sensor protein QseC; Provisional |
480-666 |
1.33e-09 |
|
sensor protein QseC; Provisional
Pssm-ID: 182388 [Multi-domain] Cd Length: 449 Bit Score: 60.82 E-value: 1.33e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552383312 480 SNVSHDLKTPLTGIKNYVELLQQDSIDEETRKEYTETLNQYIDRLSTLIEDLFEVSKVNSGNINLDLMELNLIQLIEQTK 559
Cdd:PRK10337 242 SDAAHELRSPLAALKVQTEVAQLSDDDPQARKKALLQLHAGIDRATRLVDQLLTLSRLDSLDNLQDVAEIPLEDLLQSAV 321
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552383312 560 decfevlnsrgLEMIMTS--ANSEIALMLDGDKTYR---------IFENLFNNVAKYALPSTRVYIDIIESEEDVMVEIK 628
Cdd:PRK10337 322 -----------MDIYHTAqqAGIDVRLTLNAHPVIRtgqplllslLVRNLLDNAIRYSPQGSVVDVTLNARNFTVRDNGP 390
|
170 180 190
....*....|....*....|....*....|....*...
gi 2552383312 629 NISASQMnftsEEIVERFVRgDKSRHESGSGIGLAIVK 666
Cdd:PRK10337 391 GVTPEAL----ARIGERFYR-PPGQEATGSGLGLSIVR 423
|
|
| CitA |
COG3290 |
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction ... |
442-691 |
3.43e-09 |
|
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction mechanisms];
Pssm-ID: 442519 [Multi-domain] Cd Length: 389 Bit Score: 59.48 E-value: 3.43e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552383312 442 EDVGVFNSLKDefrniKTGFEEAVREETKSQNMRTELISNvSHDLKTPLTGIKnyvELLQQDSIDEetrkeytetLNQYI 521
Cdd:COG3290 162 RVVGAVATFRD-----RTELERLEEELEGVKELAEALRAQ-RHDFRNHLHTIS---GLLQLGEYDE---------ALEYI 223
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552383312 522 DRLSTLIEDLFEVSKVNSGNINLDLMelnLIQLIEQTKDecfevlnsRGLEMIMTSANSEIALMLDGDKTYRIFENLFNN 601
Cdd:COG3290 224 DEISEELQELIDSLLSRIGNPVLAAL---LLGKAARARE--------RGIDLTIDIDSDLPDLPLSDTDLVTILGNLLDN 292
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552383312 602 ----VAKYALPSTRVYIDIIESEEDVMVEIKNisasqmNFT--SEEIVER-FVRGDKSRHESGSGIGLAIVKSYVEAQGG 674
Cdd:COG3290 293 aieaVEKLPEEERRVELSIRDDGDELVIEVED------SGPgiPEELLEKiFERGFSTKLGEGRGLGLALVKQIVEKYGG 366
|
250
....*....|....*..
gi 2552383312 675 SFKIDIDGDLFKAIIVF 691
Cdd:COG3290 367 TIEVESEEGEGTVFTVR 383
|
|
| PRK09303 |
PRK09303 |
histidine kinase; |
463-674 |
9.65e-09 |
|
histidine kinase;
Pssm-ID: 236462 [Multi-domain] Cd Length: 380 Bit Score: 58.04 E-value: 9.65e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552383312 463 EAVREETKSQNmrtELISNVSHDLKTPLTGIKNYVELLQQDSIDEETRKEYTETLN---------QYIDRLSTlieDLFE 533
Cdd:PRK09303 142 ETLLEQLKFKD---RVLAMLAHDLRTPLTAASLALETLELGQIDEDTELKPALIEQlqdqarrqlEEIERLIT---DLLE 215
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552383312 534 VSKVNSGNINLDLMELNLIQLIEQTKDECFEVLNSRGLEmIMTSANSEIALML-DGDKTYRIFENLFNNVAKYALPSTRV 612
Cdd:PRK09303 216 VGRTRWEALRFNPQKLDLGSLCQEVILELEKRWLAKSLE-IQTDIPSDLPSVYaDQERIRQVLLNLLDNAIKYTPEGGTI 294
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2552383312 613 YIDIIE-SEEDVMVEIKN----ISASQmnftSEEIVERFVRGDKSRHESGSGIGLAIVKSYVEAQGG 674
Cdd:PRK09303 295 TLSMLHrTTQKVQVSICDtgpgIPEEE----QERIFEDRVRLPRDEGTEGYGIGLSVCRRIVRVHYG 357
|
|
| PRK11100 |
PRK11100 |
sensory histidine kinase CreC; Provisional |
472-675 |
1.65e-08 |
|
sensory histidine kinase CreC; Provisional
Pssm-ID: 236846 [Multi-domain] Cd Length: 475 Bit Score: 57.55 E-value: 1.65e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552383312 472 QNMRTEL---------ISNVSHDLKTPLTGIKNYVELLqQDSIDEETRKEYTETLNQYIDRLSTLIEDLFEVSKVNSGNI 542
Cdd:PRK11100 244 ESMRVKLegkayveqyVQTLTHELKSPLAAIRGAAELL-QEDPPPEDRARFTGNILTQSARLQQLIDRLLELARLEQRQE 322
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552383312 543 NLDLMELNLIQLIEQTKDECFEVLNSRGLEMIMTSANSEIAlmldGDKTY--RIFENLFNNVAKYALPSTRVYIDIIESE 620
Cdd:PRK11100 323 LEVLEPVALAALLEELVEAREAQAAAKGITLRLRPDDARVL----GDPFLlrQALGNLLDNAIDFSPEGGTITLSAEVDG 398
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 2552383312 621 EDVMVEIKNISASQMNFTSEEIVERF---VRGDKSRheSGSGIGLAIVKSYVEAQGGS 675
Cdd:PRK11100 399 EQVALSVEDQGPGIPDYALPRIFERFyslPRPANGR--KSTGLGLAFVREVARLHGGE 454
|
|
| HATPase_BaeS-like |
cd16946 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
587-675 |
6.06e-08 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BaeS HK of the BaeS/BaeR two-component regulatory system (TCS), which responds to envelope stress. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensory domain.
Pssm-ID: 340422 [Multi-domain] Cd Length: 109 Bit Score: 51.31 E-value: 6.06e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552383312 587 DGDKTYRIFENLFNNVAKYALPSTRVYIDIIESEEDVMVEIKN----ISASQMnftsEEIVERFVRGDKSRHES--GSGI 660
Cdd:cd16946 1 DRDRLQQLFVNLLENSLRYTDTGGKLRIRAAQTPQEVRLDVEDsapgVSDDQL----ARLFERFYRVESSRNRAsgGSGL 76
|
90
....*....|....*
gi 2552383312 661 GLAIVKSYVEAQGGS 675
Cdd:cd16946 77 GLAICHNIALAHGGT 91
|
|
| KinE |
COG5809 |
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome ... |
477-681 |
8.40e-08 |
|
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444511 [Multi-domain] Cd Length: 489 Bit Score: 55.37 E-value: 8.40e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552383312 477 ELISNVSHDLKTPLTGIKNYVELLqQDSIDEEtRKEYTETLNQYIDRLSTLIEDLFEVSKVNSGNINldlmELNLIQLIE 556
Cdd:COG5809 272 ELAAGIAHEIRNPLTSLKGFIQLL-KDTIDEE-QKTYLDIMLSELDRIESIISEFLVLAKPQAIKYE----PKDLNTLIE 345
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552383312 557 QTkdecFEVL----NSRGLEMIMTSANSEIALMLDGDKTYRIFENLFNNvAKYALPST-RVYIDI-IESEEDVMVEIKN- 629
Cdd:COG5809 346 EV----IPLLqpqaLLKNVQIELELEDDIPDILGDENQLKQVFINLLKN-AIEAMPEGgNITIETkAEDDDKVVISVTDe 420
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 2552383312 630 ---ISASQMnftsEEIVERFVrgdkSRHESGSGIGLAIVKSYVEAQGGsfKIDID 681
Cdd:COG5809 421 gcgIPEERL----KKLGEPFY----TTKEKGTGLGLMVSYKIIEEHGG--KITVE 465
|
|
| PRK11466 |
PRK11466 |
hybrid sensory histidine kinase TorS; Provisional |
463-678 |
1.29e-07 |
|
hybrid sensory histidine kinase TorS; Provisional
Pssm-ID: 236914 [Multi-domain] Cd Length: 914 Bit Score: 55.30 E-value: 1.29e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552383312 463 EAVREETKSQNMRTELISNVSHDLKTPLTGIKNYVELLQQDSIDEETRkEYTETLNQYIDRLSTLIEDLFEVSKVNSGNI 542
Cdd:PRK11466 432 QARAEAEKASQAKSAFLAAMSHEIRTPLYGILGTAQLLADNPALNAQR-DDLRAITDSGESLLTILNDILDYSAIEAGGK 510
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552383312 543 NLDLME--LNLIQLIEQTKDECFEVLNSRGLEMIMTSANS-EIALMLDGDKTYRIFENLFNNVAKYalpSTRVYIdIIES 619
Cdd:PRK11466 511 NVSVSDepFEPRPLLESTLQLMSGRVKGRPIRLATDIADDlPTALMGDPRRIRQVITNLLSNALRF---TDEGSI-VLRS 586
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2552383312 620 ---EEDVMVEIKN----ISASQMNftseEIVERFVRGDKSRheSGSGIGLAIVKSYVEAQGGSFKI 678
Cdd:PRK11466 587 rtdGEQWLVEVEDsgcgIDPAKLA----EIFQPFVQVSGKR--GGTGLGLTISSRLAQAMGGELSA 646
|
|
| HATPase_EnvZ-like |
cd16950 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
593-675 |
1.95e-07 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli EnvZ and Pseudomonas aeruginosa BfmS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli EnvZ of the EnvZ-OmpR two-component regulatory system (TCS), which functions in osmoregulation. It also contains the HATPase domain of Pseudomonas aeruginosa BfmS, the HK of the BfmSR TCS, which functions in the regulation of the rhl quorum-sensing system and bacterial virulence in P. aeruginosa. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a periplasmic domain.
Pssm-ID: 340426 [Multi-domain] Cd Length: 101 Bit Score: 49.75 E-value: 1.95e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552383312 593 RIFENLFNNVAKYALPSTRVYIDIIESEEDVMVEIKN--ISASQMnftsEEIVERFVRGDKSRHESGSGIGLAIVKSYVE 670
Cdd:cd16950 3 RVLSNLVDNALRYGGGWVEVSSDGEGNRTRIQVLDNGpgIAPEEV----DELFQPFYRGDNARGTSGTGLGLAIVQRISD 78
|
....*
gi 2552383312 671 AQGGS 675
Cdd:cd16950 79 AHGGS 83
|
|
| cpxA |
PRK09470 |
envelope stress sensor histidine kinase CpxA; |
427-677 |
4.04e-07 |
|
envelope stress sensor histidine kinase CpxA;
Pssm-ID: 236532 [Multi-domain] Cd Length: 461 Bit Score: 53.01 E-value: 4.04e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552383312 427 SAENLAKGNFndEITEDV--GVfnslkDEFRNIKTGFE---EAVREETKSQNmrtELISNVSHDLKTPLTGIKNYVELL- 500
Cdd:PRK09470 200 AADEVAQGNL--RQHPELetGP-----QEFRQAGASFNqmvTALERMMTSQQ---RLLSDISHELRTPLTRLQLATALLr 269
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552383312 501 --QQDSiDEETRKEyTEtlnqyIDRLSTLIEDLFEVSK--VNSgNINLDLMELNLI--QLIEQTKDEC------FEVlnS 568
Cdd:PRK09470 270 rrQGES-KELERIE-TE-----AQRLDSMINDLLVLSRnqQKN-HLERETFKANSLwsEVLEDAKFEAeqmgksLTV--S 339
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552383312 569 RGLEMIMTSANsEIALMldgdktyRIFENLFNNVAKYALPSTRVYIDIIESEEDVMVEIKNISASQMNFtsEEIVERFVR 648
Cdd:PRK09470 340 APPGPWPINGN-PNALA-------SALENIVRNALRYSHTKIEVAFSVDKDGLTITVDDDGPGVPEEER--EQIFRPFYR 409
|
250 260 270
....*....|....*....|....*....|.
gi 2552383312 649 GD--KSRHESGSGIGLAIVKSYVEAQGGSFK 677
Cdd:PRK09470 410 VDeaRDRESGGTGLGLAIVENAIQQHRGWVK 440
|
|
| HATPase_BasS-like |
cd16940 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
597-676 |
1.79e-06 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BasS HK of the BasS-BasR two-component regulatory system (TCS). Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some contain a HAMP sensory domain, while some an N-terminal two-component sensor kinase domain.
Pssm-ID: 340417 [Multi-domain] Cd Length: 113 Bit Score: 47.02 E-value: 1.79e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552383312 597 NLFNNVAKYALPSTRVYIdIIESEEDVMVEIKNISASQMNFTSEEIVERFVRGDKsRHESGSGIGLAIVKSYVEAQGGSF 676
Cdd:cd16940 20 NLVDNAVRYSPQGSRVEI-KLSADDGAVIRVEDNGPGIDEEELEALFERFYRSDG-QNYGGSGLGLSIVKRIVELHGGQI 97
|
|
| PRK11091 |
PRK11091 |
aerobic respiration control sensor protein ArcB; Provisional |
462-674 |
2.26e-06 |
|
aerobic respiration control sensor protein ArcB; Provisional
Pssm-ID: 236842 [Multi-domain] Cd Length: 779 Bit Score: 51.09 E-value: 2.26e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552383312 462 EEAVREETKsqnmrteLISNVSHDLKTPLTGIKNYVELLQQDSIDEETRKeYTETLNqyidrlstliedlfeVSKVNSGN 541
Cdd:PRK11091 277 EKASRDKTT-------FISTISHELRTPLNGIVGLSRILLDTELTAEQRK-YLKTIH---------------VSAITLGN 333
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552383312 542 -----INLDLMELNLIQLIEQTKD-ECF--EVLN-------SRGLEMIMtsansEIALML------DGDKTYRIFENLFN 600
Cdd:PRK11091 334 ifndiIDMDKMERRKLQLDNQPIDfTDFlaDLENlsglqaeQKGLRFDL-----EPLLPLphkvitDGTRLRQILWNLIS 408
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552383312 601 NVAKYALPSTRVYIDIIESEEDVMVEIKNisaSQMNFTSEEIVERF-----VRGDK-SRHESGSGIGLAIVKSYVEAQGG 674
Cdd:PRK11091 409 NAVKFTQQGGVTVRVRYEEGDMLTFEVED---SGIGIPEDELDKIFamyyqVKDSHgGKPATGTGIGLAVSKRLAQAMGG 485
|
|
| HATPase_SpaK_NisK-like |
cd16975 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
587-678 |
3.50e-06 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis SpaK and Lactococcus lactis NisK; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Bacillus subtilis SpaK and Lactococcus lactis NisK. SpaK is the histidine kinase (HK) of the SpaK-SpaR two-component regulatory system (TCS), which is involved in the regulation of the biosynthesis of lantibiotic subtilin. NisK is the HK of the NisK-NisR TCS, which is involved in the regulation of the biosynthesis of lantibiotic nisin. SpaK and NisK may function as membrane-associated protein kinases that phosphorylate SpaR and NisR, respectively, in response to environmental signals.
Pssm-ID: 340434 [Multi-domain] Cd Length: 107 Bit Score: 46.30 E-value: 3.50e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552383312 587 DGDKTYRIFENLFNNVAKYALPSTRVYIDIIESEEDVMVEIKNisaSQMNFTSEEI---VERFVRGDKSRHESG-SGIGL 662
Cdd:cd16975 1 DTLLLSRALINIISNACQYAPEGGTVSISIYDEEEYLYFEIWD---NGHGFSEQDLkkaLELFYRDDTSRRSGGhYGMGL 77
|
90
....*....|....*.
gi 2552383312 663 AIVKSYVEAQGGSFKI 678
Cdd:cd16975 78 YIAKNLVEKHGGSLII 93
|
|
| HATPase_PhoQ-like |
cd16954 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
597-679 |
6.54e-06 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG. PhoQ is the histidine kinase (HK) of the PhoP-PhoQ two-component regulatory system (TCS), which responds to the levels of Mg2+ and Ca2+, controls virulence, mediates the adaptation to Mg2+-limiting environments, and regulates numerous cellular activities. Providencia stuartii AarG is a putative sensor kinase which controls the expression of the 2'-N-acetyltransferase and an intrinsic multiple antibiotic resistance (Mar) response in Providencia stuartii. The AarG product is similar to PhoQ in that it is able to restore wild-type levels of resistance to a Salmonella typhimurium phoQ mutant. However, the expression of the 2'-N-acetyltransferase gene and of aarP (a gene encoding a transcriptional activator of 2'-N-acetyltransferase) are not significantly affected by the levels of Mg2+ or Ca2+. Most proteins in this group contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have an accessory HAMP sensor domain, and some have an intracellular membrane -interaction PhoQ sensor domain.
Pssm-ID: 340430 [Multi-domain] Cd Length: 135 Bit Score: 46.09 E-value: 6.54e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552383312 597 NLFNNVAKYALpsTRVYIDIIESEEDVMVEIKN----ISASQMnftsEEIVERFVRGDKSRheSGSGIGLAIVKSYVEAQ 672
Cdd:cd16954 44 NLLDNACKWCL--EFVEVTARQTDGGLHLIVDDdgpgVPESQR----SKIFQRGQRLDEQR--PGQGLGLAIAKEIVEQY 115
|
....*..
gi 2552383312 673 GGSFKID 679
Cdd:cd16954 116 GGELSLS 122
|
|
| HATPase_RstB-like |
cd16939 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
593-692 |
1.02e-05 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Salmonella typhimurium RstB; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Salmonella typhimurium RstB HK of the RstA-RstB two-component regulatory system (TCS), which regulates expression of the constituents participating in pyrimidine metabolism and iron acquisition, and may be required for regulation of Salmonella motility and invasion. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensor domain.
Pssm-ID: 340416 [Multi-domain] Cd Length: 104 Bit Score: 44.73 E-value: 1.02e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552383312 593 RIFENLFNNVAKYAlpSTRVYIDIIESEEDVMVEIKN----ISASQmnftSEEIVERFVRGDKSRHES--GSGIGLAIVK 666
Cdd:cd16939 3 RALDNLLRNALRYA--HRTVRIALLVSGGRLTLIVEDdgpgIPAAA----RERVFEPFVRLDPSRDRAtgGFGLGLAIVH 76
|
90 100
....*....|....*....|....*.
gi 2552383312 667 SYVEAQGGSFKIDiDGDLFKAIIVFR 692
Cdd:cd16939 77 RVALWHGGHVECD-DSELGGACFRLT 101
|
|
| HATPase_TutC-TodS-like |
cd16925 |
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas ... |
640-678 |
1.93e-05 |
|
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas putida TodS and Thauera aromatica TutC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinase (HKs) such Pseudomonas putida TodS HK of the TodS-TodT two-component regulatory system (TCS) which controls the expression of a toluene degradation pathway. Thauera aromatica TutC may be part of a TCS that is involved in anaerobic toluene metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), PAS sensor domain(s) and a REC domain.
Pssm-ID: 340402 [Multi-domain] Cd Length: 110 Bit Score: 44.02 E-value: 1.93e-05
10 20 30 40
....*....|....*....|....*....|....*....|.
gi 2552383312 640 EEIVERF--VRGDKSRHESGSGIGLAIVKSYVEAQGGSFKI 678
Cdd:cd16925 55 EEIFERFrqGDGSSTRAHGGTGLGLSIVKEFVELHGGTVTV 95
|
|
| HATPase_DpiB-CitA-like |
cd16915 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
596-675 |
2.87e-05 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 DpiB, DcuS, and Bacillus subtilis CitS, DctS, and YufL; This family includes histidine kinase-like ATPase domains of Escherichia coli K-12 DpiB and DcuS, and Bacillus subtilis CitS, DctS and MalK histidine kinases (HKs) all of which are two component transduction systems (TCSs). E. coli K-12 DpiB (also known as CitA) is the histidine kinase (HK) of DpiA-DpiB, a two-component signal transduction system (TCS) required for the expression of citrate-specific fermentation genes and genes involved in plasmid inheritance. E. coli K-12 DcuS (also known as YjdH) is the HK of DcuS-DcuR, a TCS that in the presence of the extracellular C4-dicarboxlates, activates the expression of the genes of anaerobic fumarate respiration and of aerobic C4-dicarboxylate uptake. CitS is the HK of Bacillus subtilis CitS-CitT, a TCS which regulates expression of CitM, the Mg-citrate transporter. Bacillus subtilis DctS forms a tripartite sensor unit (DctS/DctA/DctB) for sensing C4 dicarboxylates. Bacillus subtilis MalK (also known as YfuL) is the HK of MalK-MalR (YufL-YufM) a TCS which regulates the expression of the malate transporters MaeN (YufR) and YflS, and is essential for utilization of malate in minimal medium. Proteins having this DpiB-CitA-like HATPase domain generally have sensor domains such as Cache and PAS, and a histidine kinase A (HisKA)-like SpoOB-type, alpha-helical domain.
Pssm-ID: 340392 [Multi-domain] Cd Length: 104 Bit Score: 43.43 E-value: 2.87e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552383312 596 ENLFNNVAKYALPSTRVYIDIIESEEDVMVEIKNISASqmnfTSEEIVER-FVRGDKSRHESGSGIGLAIVKSYVEAQGG 674
Cdd:cd16915 10 DNALDALAATGAPNKQVEVFLRDEGDDLVIEVRDTGPG----IAPELRDKvFERGVSTKGQGERGIGLALVRQSVERLGG 85
|
.
gi 2552383312 675 S 675
Cdd:cd16915 86 S 86
|
|
| ComP |
COG4585 |
Signal transduction histidine kinase ComP [Signal transduction mechanisms]; |
490-679 |
3.06e-05 |
|
Signal transduction histidine kinase ComP [Signal transduction mechanisms];
Pssm-ID: 443642 [Multi-domain] Cd Length: 252 Bit Score: 46.15 E-value: 3.06e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552383312 490 LTGIKNYVELLQQ--DSIDEETRKEytetLNQYIDRLSTLIEDLFEVSKvnsgniNLDLMELNLIQLIEQTKDECFEVLN 567
Cdd:COG4585 69 LSAIKLQLEAARRllDADPEAAREE----LEEIRELAREALAELRRLVR------GLRPPALDDLGLAAALEELAERLLR 138
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552383312 568 SRGLEMIMTSANSEIALMLDGDKT-YRIFENLFNNVAKYAlPSTRVYIDIIESEEDVMVEIKNisasqmNftseeiverf 646
Cdd:COG4585 139 AAGIRVELDVDGDPDRLPPEVELAlYRIVQEALTNALKHA-GATRVTVTLEVDDGELTLTVRD------D---------- 201
|
170 180 190
....*....|....*....|....*....|...
gi 2552383312 647 VRGDKSRHESGSGIGLAIVKSYVEAQGGSFKID 679
Cdd:COG4585 202 GVGFDPEAAPGGGLGLRGMRERAEALGGTLTIG 234
|
|
| KinA |
COG5805 |
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle ... |
477-679 |
6.12e-05 |
|
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444507 [Multi-domain] Cd Length: 496 Bit Score: 46.26 E-value: 6.12e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552383312 477 ELISNVSHDLKTPLTGIKNYVELLQqdsIDEETRKEYTETLNQYIDRLSTLIEDLFEVSK---VNSGNINLDLMELNLIQ 553
Cdd:COG5805 289 QLAAGIAHEIRNPLTSIKGFLQLLQ---PGIEDKEEYFDIMLSELDRIESIISEFLALAKpqaVNKEKENINELIQDVVT 365
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552383312 554 LIEQTKdecfeVLNSRGLEMIMTSANSEIalMLDGDKTYRIFENLFNNvAKYALPS-TRVYIDIIESEEDVMVEIKN--- 629
Cdd:COG5805 366 LLETEA-----ILHNIQIRLELLDEDPFI--YCDENQIKQVFINLIKN-AIEAMPNgGTITIHTEEEDNSVIIRVIDegi 437
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 2552383312 630 -ISASQMNftseEIVERFVrgdkSRHESGSGIGLAIVKSYVEAQGGSFKID 679
Cdd:COG5805 438 gIPEERLK----KLGEPFF----TTKEKGTGLGLMVSYKIIENHNGTIDID 480
|
|
| PRK10618 |
PRK10618 |
phosphotransfer intermediate protein in two-component regulatory system with RcsBC; Provisional |
464-630 |
7.85e-05 |
|
phosphotransfer intermediate protein in two-component regulatory system with RcsBC; Provisional
Pssm-ID: 236726 [Multi-domain] Cd Length: 894 Bit Score: 46.08 E-value: 7.85e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552383312 464 AVREETKSQNMRTELISNVSHDLKTPLTGIKNYVELLQQDSIDEETRKEYTETLNQYiDRLSTLIEDLFEVSKVNSGNIN 543
Cdd:PRK10618 439 AQREYEKNQQARKAFLQNIGDELKQPLQSLAQLAAQLRQTSDEEQQQPELDQLAEQS-DVLVRLVDNIQLLNMLETQDWK 517
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552383312 544 LDLMELNLIQLIEQTKDECFEVLNSRGLEM-IMTSANSEIALMLDGDKTYRIFENLFNnvakYALPST------------ 610
Cdd:PRK10618 518 PEQELFSLQDLIDEVLPEVLPAIKRKGLQLlIHNHLKAEQLRIGDRDALRKILLLLLN----YAITTTaygkitlevdqd 593
|
170 180
....*....|....*....|....*.
gi 2552383312 611 -----RVYIDIIESEEDVMV-EIKNI 630
Cdd:PRK10618 594 esspdRLTIRILDTGAGVSIkELDNL 619
|
|
| COG4192 |
COG4192 |
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal ... |
344-678 |
2.29e-04 |
|
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal transduction mechanisms];
Pssm-ID: 443346 [Multi-domain] Cd Length: 640 Bit Score: 44.29 E-value: 2.29e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552383312 344 DTLIGDLCRNIKGGINKLGNvdlsdnINRTIMKYAliNTLVILIMIclwwFGIFLAIIyavVSYLWVKEKvdkIKADYDV 423
Cdd:COG4192 296 RTQISGLVGNSREQLVALNQ------ETAQLVQQS--GILLLAIAL----LSLLLAVL---INYFYVRRR---LVKRLNA 357
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552383312 424 LLVSAENLAKGNF--------NDEITE---DVGVF-NSLKDEFRNIKTGFEEAVREETKSQNMRTELI------------ 479
Cdd:COG4192 358 LSDAMAAIAAGDLdvpipvdgNDEIGRiarLLRVFrDQAIEKTQELETEIEERKRIEKNLRQTQDELIqaakmavvgqtm 437
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552383312 480 SNVSHDLKTPLTGIKNYVEllqqdSIDEETRKEYTETLNQYIDRLSTLIEDLFEVSK---VNSGNINLDLMELNLIQLIE 556
Cdd:COG4192 438 TSLAHELNQPLNAMSMYLF-----SAKKALEQENYAQLPTSLDKIEGLIERMDKIIKslrQFSRKSDTPLQPVDLRQVIE 512
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552383312 557 QTkdecFEVLNSRG-LEMIMTSANSEIALMLDGDKTYRIFENLFNNVAKYALPSTRVYIDIIESEEDVMVEIKNisasqm 635
Cdd:COG4192 513 QA----WELVESRAkPQQITLHIPDDLMVQGDQVLLEQVLVNLLVNALDAVATQPQISVDLLSNAENLRVAISD------ 582
|
330 340 350 360
....*....|....*....|....*....|....*....|...
gi 2552383312 636 NFTSEEIVERFVRGDKSRHESGSGIGLAIVKSYVEAQGGSFKI 678
Cdd:COG4192 583 NGNGWPLVDKLFTPFTTTKEVGLGLGLSICRSIMQQFGGDLYL 625
|
|
| HATPase_CpxA-like |
cd16949 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
592-677 |
2.47e-04 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CpxA; This family includes the histidine kinase-like ATPase (HATPase) domains of two-component sensor histidine kinase (HKs) similar to Escherichia coli CpxA, HK of the CpxA-CpxR two-component regulatory system (TCS) which may function in acid stress and in cell wall stability. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a CpxA family periplasmic domain.
Pssm-ID: 340425 [Multi-domain] Cd Length: 104 Bit Score: 40.77 E-value: 2.47e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552383312 592 YRIFENLFNNVAKYAlPSTrVYIDIIESEEDVMVEIKN----ISASQMnftsEEIVERFVRGDKSRH-ES-GSGIGLAIV 665
Cdd:cd16949 2 ARALENVLRNALRYS-PSK-ILLDISQDGDQWTITITDdgpgVPEDQL----EQIFLPFYRVDSARDrESgGTGLGLAIA 75
|
90
....*....|..
gi 2552383312 666 KSYVEAQGGSFK 677
Cdd:cd16949 76 ERAIEQHGGKIK 87
|
|
| HATPase_EcPhoR-like |
cd16952 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
595-666 |
5.38e-04 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli PhoR; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Escherichia coli or Vibrio cholera PhoR, the histidine kinase (HK) of PhoB-PhoR a two-component signal transduction system (TCS) involved in phosphate regulation. PhoR monitors extracellular inorganic phosphate (Pi) availability and PhoB, the response regulator, regulates transcription of genes of the phosphate regulon. PhoR is a bifunctional histidine autokinase/phospho-PhoB phosphatase; in phosphate deficiency, it autophosphorylates and Pi is transferred to PhoB, and when environmental Pi is abundant, it removes the phosphoryl group from phosphorylated PhoB. Other roles of PhoB-PhoR TCS have been described, including motility, biofilm formation, intestinal colonization, and virulence in V. cholera. E.coli PhoR and Bacillus subtilis PhoR (whose HATPase domain belongs to a different family) sense very different signals in each bacterium. In E. coli the PhoR signal comes from phosphate transport mediated by the PstSCAB2 phosphate transporter and the PhoU chaperone-like protein while in B. subtilis, the PhoR activation signal comes from wall teichoic acid (WTA) metabolism.
Pssm-ID: 340428 [Multi-domain] Cd Length: 108 Bit Score: 39.88 E-value: 5.38e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2552383312 595 FENLFNNVAKYALPSTRVYIDIIESEEDVMVEIKNISASQMNFTSEEIVERFVRGDKS--RHESGSGIGLAIVK 666
Cdd:cd16952 5 FSNLVSNAVKYTPPSDTITVRWSQEESGARLSVEDTGPGIPPEHIPRLTERFYRVDIErcRNTGGTGLGLAIVK 78
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| HATPase_YcbM-like |
cd16947 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
593-675 |
3.92e-03 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis YcbM; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis YcbM, a HK of the two-component system YcbM-YcbL. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA).
Pssm-ID: 340423 [Multi-domain] Cd Length: 125 Bit Score: 37.88 E-value: 3.92e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552383312 593 RIFENLFNNVAKYALPSTRVYIDIIESEEDVMVEI----KNISASQmnftSEEIVERFVRGDKSRHES--GSGIGLAIVK 666
Cdd:cd16947 23 RILKNLISNAIKYGSDGKFLGMTLREDEKHVYIDIwdkgKGISETE----KDHVFERLYTLEDSRNSAkqGNGLGLTITK 98
|
....*....
gi 2552383312 667 SYVEAQGGS 675
Cdd:cd16947 99 RLAESMGGS 107
|
|
| HATPase_FilI-like |
cd16921 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
594-679 |
4.52e-03 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Methanosaeta harundinacea FilI and some hybrid sensor histidine kinases; This family includes FilI, the histidine kinase (HK) component of FilI-FilRs, a two-component signal transduction system (TCS) of the methanogenic archaeon, Methanosaeta harundinacea, which is involved in regulating methanogenesis. The cytoplasmic HK core consists of a C-terminal HK-like ATPase domain (represented here) and a histidine kinase dimerization and phosphoacceptor domain (HisKA) domain, which, in FilI, are coupled to CHASE, HAMP, PAS, and GAF sensor domains. FilI-FilRs catalyzes the phosphotransfer between FilI (HK) and FilRs (FilR1 and FilR2, response regulators) of the TCS. TCSs are predicted to be of bacterial origin, and acquired by archaea by horizontal gene transfer. This model also includes related HATPase domains such as that of Synechocystis sp. PCC6803 phytochrome-like protein Cph1. Proteins having this HATPase domain and HisKA domain also have accessory sensor domains such as CHASE, GAF, HAMP and PAS; some are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340398 [Multi-domain] Cd Length: 105 Bit Score: 37.31 E-value: 4.52e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2552383312 594 IFENLFNNVAKYALPSTRVYIDI--IESEEDVMVEIK-NISASQMNFtSEEIVERFVRGDkSRHES-GSGIGLAIVKSYV 669
Cdd:cd16921 4 VLTNLLGNAIKFRRPRRPPRIEVgaEDVGEEWTFYVRdNGIGIDPEY-AEKVFGIFQRLH-SREEYeGTGVGLAIVRKII 81
|
90
....*....|
gi 2552383312 670 EAQGGSFKID 679
Cdd:cd16921 82 ERHGGRIWLE 91
|
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