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Conserved domains on  [gi|2552840606|ref|WP_302969339|]
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T9SS type A sorting domain-containing protein [Barnesiella intestinihominis]

Protein Classification

T9SS type A sorting domain-containing protein( domain architecture ID 10024511)

T9SS type A sorting domain-containing protein may function in protein secretion; the conserved C-terminal domain functions as an outer membrane translocation signal for export of virulence factors to the cell surface

Gene Ontology:  GO:0005576
PubMed:  24007199

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Por_Secre_tail TIGR04183
Por secretion system C-terminal sorting domain; Species that include Porphyromonas gingivalis, ...
 779-850 6.76e-08

Por secretion system C-terminal sorting domain; Species that include Porphyromonas gingivalis, Fibrobacter succinogenes, Flavobacterium johnsoniae, Cytophaga hutchinsonii, Gramella forsetii, Prevotella intermedia, and Salinibacter ruber average twenty or more copies of a C-terminal domain, represented by this model, associated with sorting to the outer membrane and covalent modification.


:

Pssm-ID: 275036 [Multi-domain]  Cd Length: 72  Bit Score: 50.10  E-value: 6.76e-08
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2552840606 779 AFPNPVIRNLTIY--SDTEIGKVSLFDMMGNCVYTGRVYDKVyTVDMDNLPAGAYILSVldESGNCIKKQKVIK 850
Cdd:TIGR04183   1 IYPNPAKGTLIIIllSSSGKVKVEIYDLSGKLVKKTTLNNSN-SIDLSNLSSGVYIVKI--TTGNGTITKKIIK 71
 
Name Accession Description Interval E-value
Por_Secre_tail TIGR04183
Por secretion system C-terminal sorting domain; Species that include Porphyromonas gingivalis, ...
 779-850 6.76e-08

Por secretion system C-terminal sorting domain; Species that include Porphyromonas gingivalis, Fibrobacter succinogenes, Flavobacterium johnsoniae, Cytophaga hutchinsonii, Gramella forsetii, Prevotella intermedia, and Salinibacter ruber average twenty or more copies of a C-terminal domain, represented by this model, associated with sorting to the outer membrane and covalent modification.


Pssm-ID: 275036 [Multi-domain]  Cd Length: 72  Bit Score: 50.10  E-value: 6.76e-08
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2552840606 779 AFPNPVIRNLTIY--SDTEIGKVSLFDMMGNCVYTGRVYDKVyTVDMDNLPAGAYILSVldESGNCIKKQKVIK 850
Cdd:TIGR04183   1 IYPNPAKGTLIIIllSSSGKVKVEIYDLSGKLVKKTTLNNSN-SIDLSNLSSGVYIVKI--TTGNGTITKKIIK 71
Por_Secre_tail pfam18962
Secretion system C-terminal sorting domain; Species that include Porphyromonas gingivalis, ...
 780-848 1.01e-06

Secretion system C-terminal sorting domain; Species that include Porphyromonas gingivalis, Fibrobacter succinogenes, Flavobacterium johnsoniae, Cytophaga hutchinsonii, Gramella forsetii, Prevotella intermedia, and Salinibacter ruber have on average twenty or more copies of this C-terminal domain, associated with sorting to the outer membrane and covalent modification. This domain targets proteins to type IX secretion systems and is secreted then cleaved off by a C-terminal signal peptidease. Based on similarity to other families it is likely that this domain adopts an immunoglobulin like fold.


Pssm-ID: 436869 [Multi-domain]  Cd Length: 75  Bit Score: 46.83  E-value: 1.01e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2552840606 780 FPNPVIRNLTIY---SDTEIGKVSLFDMMGNCVY--TGRVYDKVYTVDMDNLPAGAYILSVLDESGNCIKKQKV 848
Cdd:pfam18962   2 YPNPAKDVLNISlknSNSSNLNISIYDILGKLVKsnSKTNGNNTKTIDVSNLSSGIYFVKINSGNGSTTKKLII 75
 
Name Accession Description Interval E-value
Por_Secre_tail TIGR04183
Por secretion system C-terminal sorting domain; Species that include Porphyromonas gingivalis, ...
 779-850 6.76e-08

Por secretion system C-terminal sorting domain; Species that include Porphyromonas gingivalis, Fibrobacter succinogenes, Flavobacterium johnsoniae, Cytophaga hutchinsonii, Gramella forsetii, Prevotella intermedia, and Salinibacter ruber average twenty or more copies of a C-terminal domain, represented by this model, associated with sorting to the outer membrane and covalent modification.


Pssm-ID: 275036 [Multi-domain]  Cd Length: 72  Bit Score: 50.10  E-value: 6.76e-08
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2552840606 779 AFPNPVIRNLTIY--SDTEIGKVSLFDMMGNCVYTGRVYDKVyTVDMDNLPAGAYILSVldESGNCIKKQKVIK 850
Cdd:TIGR04183   1 IYPNPAKGTLIIIllSSSGKVKVEIYDLSGKLVKKTTLNNSN-SIDLSNLSSGVYIVKI--TTGNGTITKKIIK 71
Por_Secre_tail pfam18962
Secretion system C-terminal sorting domain; Species that include Porphyromonas gingivalis, ...
 780-848 1.01e-06

Secretion system C-terminal sorting domain; Species that include Porphyromonas gingivalis, Fibrobacter succinogenes, Flavobacterium johnsoniae, Cytophaga hutchinsonii, Gramella forsetii, Prevotella intermedia, and Salinibacter ruber have on average twenty or more copies of this C-terminal domain, associated with sorting to the outer membrane and covalent modification. This domain targets proteins to type IX secretion systems and is secreted then cleaved off by a C-terminal signal peptidease. Based on similarity to other families it is likely that this domain adopts an immunoglobulin like fold.


Pssm-ID: 436869 [Multi-domain]  Cd Length: 75  Bit Score: 46.83  E-value: 1.01e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2552840606 780 FPNPVIRNLTIY---SDTEIGKVSLFDMMGNCVY--TGRVYDKVYTVDMDNLPAGAYILSVLDESGNCIKKQKV 848
Cdd:pfam18962   2 YPNPAKDVLNISlknSNSSNLNISIYDILGKLVKsnSKTNGNNTKTIDVSNLSSGIYFVKINSGNGSTTKKLII 75
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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