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Conserved domains on  [gi|2558747382|ref|WP_304636408|]
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class II fructose-bisphosphate aldolase, partial [uncultured Muribaculum sp.]

Protein Classification

beta/alpha barrel domain-containing protein( domain architecture ID 229392)

beta/alpha barrel domain-containing protein belongs to a large superfamily with a wide variety of enzymatic functions

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
TIM super family cl21457
TIM-like beta/alpha barrel domains; A large family of domains similar to triose phosphate ...
 1-206 7.24e-144

TIM-like beta/alpha barrel domains; A large family of domains similar to triose phosphate isomerase (TIM) which, in general, share an eight beta/alpha closed barrel structure.


The actual alignment was detected with superfamily member PRK07084:

Pssm-ID: 473867  Cd Length: 321  Bit Score: 403.34  E-value: 7.24e-144
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2558747382   1 VALTKKVVDYAHQYDVTVEGELGVLAGVEDEVSSDHHTYTDPEEVIDFATRTGCDSLAISIGTSHGAYKFKPEQCtrnad 80
Cdd:PRK07084  125 VALTKKVVEYAHQFDVTVEGELGVLAGVEDEVSAEHHTYTQPEEVEDFVKKTGVDSLAISIGTSHGAYKFKPGQC----- 199

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2558747382  81 gklvPPPLAFDVLDAVMEKLPGFPIVLHGSSSVPQDEVDTINKYGGKLPDAIGIPEEELRKASKSAVCKINIDSDSRLAM 160
Cdd:PRK07084  200 ----PPPLRFDILEEIEKRIPGFPIVLHGSSSVPQEYVKTINEYGGKLKDAIGIPEEQLRKAAKSAVCKINIDSDGRLAM 275

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 2558747382 161 TAAVRKTLFEHPEEFDPRKYLGPARDNMEKLYKHKIEAVLGSKDKA 206
Cdd:PRK07084  276 TAAIRKVFDEKPEEFDPRKYLGPARDELKKLYKHKIINVLGSNGKA 321
 
Name Accession Description Interval E-value
PRK07084 PRK07084
class II fructose-1,6-bisphosphate aldolase;
1-206 7.24e-144

class II fructose-1,6-bisphosphate aldolase;


Pssm-ID: 180829  Cd Length: 321  Bit Score: 403.34  E-value: 7.24e-144
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2558747382   1 VALTKKVVDYAHQYDVTVEGELGVLAGVEDEVSSDHHTYTDPEEVIDFATRTGCDSLAISIGTSHGAYKFKPEQCtrnad 80
Cdd:PRK07084  125 VALTKKVVEYAHQFDVTVEGELGVLAGVEDEVSAEHHTYTQPEEVEDFVKKTGVDSLAISIGTSHGAYKFKPGQC----- 199

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2558747382  81 gklvPPPLAFDVLDAVMEKLPGFPIVLHGSSSVPQDEVDTINKYGGKLPDAIGIPEEELRKASKSAVCKINIDSDSRLAM 160
Cdd:PRK07084  200 ----PPPLRFDILEEIEKRIPGFPIVLHGSSSVPQEYVKTINEYGGKLKDAIGIPEEQLRKAAKSAVCKINIDSDGRLAM 275

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 2558747382 161 TAAVRKTLFEHPEEFDPRKYLGPARDNMEKLYKHKIEAVLGSKDKA 206
Cdd:PRK07084  276 TAAIRKVFDEKPEEFDPRKYLGPARDELKKLYKHKIINVLGSNGKA 321
Fba COG0191
Fructose/tagatose bisphosphate aldolase [Carbohydrate transport and metabolism]; Fructose ...
 1-206 3.28e-80

Fructose/tagatose bisphosphate aldolase [Carbohydrate transport and metabolism]; Fructose/tagatose bisphosphate aldolase is part of the Pathway/BioSystem: Glycolysis


Pssm-ID: 439961  Cd Length: 283  Bit Score: 240.76  E-value: 3.28e-80
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2558747382   1 VALTKKVVDYAHQYDVTVEGELGVLAGVEDEVSSDHH--TYTDPEEVIDFATRTGCDSLAISIGTSHGAYKFKPEqctrn 78
Cdd:COG0191   113 IAITKEVVEYAHAAGVSVEAELGVVGGEEDGVDVDDAeaLYTDPEEAAEFVEETGVDALAVAIGTVHGVYKGEPK----- 187

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2558747382  79 adgklvpppLAFDVLDAVMEKLPgFPIVLHGSSsvpqdevdtinkyggklpdaiGIPEEELRKASKSAVCKINIDSDSRL 158
Cdd:COG0191   188 ---------LDFDRLKEIREAVP-VPLVLHGGS---------------------GVPDEEIREAIKLGVAKINIDTDLRL 236

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 2558747382 159 AMTAAVRKTLFEHPEEFDPRKYLGPARDNMEKLYKHKIEaVLGSKDKA 206
Cdd:COG0191   237 AFTAAVREYLAENPDKYDPRKYLKPAREAMKEVVKEKIR-LFGSAGKA 283
TBP_aldolase_IIB cd00947
Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase ...
 1-202 3.99e-77

Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1,6-bisphosphate. There is an absolute requirement for a divalent metal ion, usually zinc, and in addition the enzymes are activated by monovalent cations such as Na+. The type A and type B Class II FBPA's differ in the presence and absence of distinct indels in the sequence that result in differing loop lengths in the structures.


Pssm-ID: 238477  Cd Length: 276  Bit Score: 232.42  E-value: 3.99e-77
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2558747382   1 VALTKKVVDYAHQYDVTVEGELGVLAGVEDEVSSDHHTYTDPEEVIDFATRTGCDSLAISIGTSHGAYKFkpeqctrnad 80
Cdd:cd00947   109 VAKTKEVVELAHAYGVSVEAELGRIGGEEDGVVGDEGLLTDPEEAEEFVEETGVDALAVAIGTSHGAYKG---------- 178

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2558747382  81 gklVPPPLAFDVLDAVMEKLPgFPIVLHGSSsvpqdevdtinkyggklpdaiGIPEEELRKASKSAVCKINIDSDSRLAM 160
Cdd:cd00947   179 ---GEPKLDFDRLKEIAERVN-VPLVLHGGS---------------------GIPDEQIRKAIKLGVCKININTDLRLAF 233

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 2558747382 161 TAAVRKTLFEHPEEFDPRKYLGPARDNMEKLYKHKIEaVLGS 202
Cdd:cd00947   234 TAALREYLAENPKEFDPRKYLAPAIEAVKEVVKHKME-LFGS 274
F_bP_aldolase pfam01116
Fructose-bisphosphate aldolase class-II;
1-205 4.26e-73

Fructose-bisphosphate aldolase class-II;


Pssm-ID: 460071  Cd Length: 276  Bit Score: 222.29  E-value: 4.26e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2558747382   1 VALTKKVVDYAHQYDVTVEGELGVLAGVEDEVSSDHHTYTDPEEVIDFATRTGCDSLAISIGTSHGAYKFKPEqctrnad 80
Cdd:pfam01116 113 IAITKEVVEYAHARGVSVEAELGRIGGEEDGVVVDEKLYTDPEEAAEFVEATGVDALAVAIGNVHGVYKPGPK------- 185

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2558747382  81 gklvpppLAFDVLDAVMEKLPgFPIVLHGSSsvpqdevdtinkyggklpdaiGIPEEELRKASKSAVCKINIDSDSRLAM 160
Cdd:pfam01116 186 -------LDFDRLKEIQEAVP-VPLVLHGGS---------------------GVPDEDIRKAIKLGVCKINIDTDLQLAF 236

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 2558747382 161 TAAVRKtlfeHPEEFDPRKYLGPARDNMEKLYKHKIEaVLGSKDK 205
Cdd:pfam01116 237 TAAVRE----YPPNKDPRKYLRPAEEAMKEVVKEKIR-LFGSAGK 276
fruc_bis_ald_ TIGR01859
fructose-1,6-bisphosphate aldolase, class II, various bacterial and amitochondriate protist; ...
 1-206 7.02e-63

fructose-1,6-bisphosphate aldolase, class II, various bacterial and amitochondriate protist; This model represents of one of several subtypes of the class II fructose-1,6-bisphosphate aldolase, an enzyme of glycolysis. The subtypes are split into several models to allow separation of a family of tagatose bisphosphate aldolases. This form is found in Gram-positive bacteria, a variety of Gram-negative, and in amitochondriate protists. The class II enzymes share homology with tagatose bisphosphate aldolase but not with class I aldolase. [Energy metabolism, Glycolysis/gluconeogenesis]


Pssm-ID: 130918  Cd Length: 282  Bit Score: 196.43  E-value: 7.02e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2558747382   1 VALTKKVVDYAHQYDVTVEGELGVLAGVEDEVSSDHHTYTDPEEVIDFATRTGCDSLAISIGTSHGayKFKPEqctrnad 80
Cdd:TIGR01859 114 LALTKKVVEIAHAKGVSVEAELGTLGGIEDGVDEKEAELADPDEAEQFVKETGVDYLAAAIGTSHG--KYKGE------- 184

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2558747382  81 gklvpPPLAFDVLDAVMEKLPgFPIVLHGSSsvpqdevdtinkyggklpdaiGIPEEELRKASKSAVCKINIDSDSRLAM 160
Cdd:TIGR01859 185 -----PGLDFERLKEIKELTN-IPLVLHGAS---------------------GIPEEQIKKAIKLGIAKINIDTDCRIAF 237

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 2558747382 161 TAAVRKTLFEHPEEFDPRKYLGPARDNMEKLYKHKIEaVLGSKDKA 206
Cdd:TIGR01859 238 TAAIRKVLTEKKDEYDPRKILGPAREAIKETVKEKMR-LFGSAGKA 282
Fbpase2_Halo NF041368
class II fructose-bisphosphate aldolase;
1-154 3.40e-28

class II fructose-bisphosphate aldolase;


Pssm-ID: 469259  Cd Length: 333  Bit Score: 108.19  E-value: 3.40e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2558747382   1 VALTKKVVDYAHQ--YDVTVEGELGVLAGVEDEVSSDHHTYTDPEEVIDFATRTGCDSLAISIGTSHGAYKfkpeqcTRN 78
Cdd:NF041368  128 VERTREVVEMVDAadEDVLVEAELGRIAGVEDGIETDEAFYTDPEQAVEFVDRTGCDLLAVSVGTQHGVAK------GRD 201

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2558747382  79 ADgklVPPPLAFDVLDAVMEKLPGFPIVLHGSSsvpqdevdtinkyggklpdaiGIPEEELRKASKSAVCKINIDS 154
Cdd:NF041368  202 LD---LRPDLAREIRDALRDHGLDTPLVVHGSS---------------------GLSPEQVRELLDAGVCKVNKNT 253
 
Name Accession Description Interval E-value
PRK07084 PRK07084
class II fructose-1,6-bisphosphate aldolase;
1-206 7.24e-144

class II fructose-1,6-bisphosphate aldolase;


Pssm-ID: 180829  Cd Length: 321  Bit Score: 403.34  E-value: 7.24e-144
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2558747382   1 VALTKKVVDYAHQYDVTVEGELGVLAGVEDEVSSDHHTYTDPEEVIDFATRTGCDSLAISIGTSHGAYKFKPEQCtrnad 80
Cdd:PRK07084  125 VALTKKVVEYAHQFDVTVEGELGVLAGVEDEVSAEHHTYTQPEEVEDFVKKTGVDSLAISIGTSHGAYKFKPGQC----- 199

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2558747382  81 gklvPPPLAFDVLDAVMEKLPGFPIVLHGSSSVPQDEVDTINKYGGKLPDAIGIPEEELRKASKSAVCKINIDSDSRLAM 160
Cdd:PRK07084  200 ----PPPLRFDILEEIEKRIPGFPIVLHGSSSVPQEYVKTINEYGGKLKDAIGIPEEQLRKAAKSAVCKINIDSDGRLAM 275

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 2558747382 161 TAAVRKTLFEHPEEFDPRKYLGPARDNMEKLYKHKIEAVLGSKDKA 206
Cdd:PRK07084  276 TAAIRKVFDEKPEEFDPRKYLGPARDELKKLYKHKIINVLGSNGKA 321
Fba COG0191
Fructose/tagatose bisphosphate aldolase [Carbohydrate transport and metabolism]; Fructose ...
 1-206 3.28e-80

Fructose/tagatose bisphosphate aldolase [Carbohydrate transport and metabolism]; Fructose/tagatose bisphosphate aldolase is part of the Pathway/BioSystem: Glycolysis


Pssm-ID: 439961  Cd Length: 283  Bit Score: 240.76  E-value: 3.28e-80
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2558747382   1 VALTKKVVDYAHQYDVTVEGELGVLAGVEDEVSSDHH--TYTDPEEVIDFATRTGCDSLAISIGTSHGAYKFKPEqctrn 78
Cdd:COG0191   113 IAITKEVVEYAHAAGVSVEAELGVVGGEEDGVDVDDAeaLYTDPEEAAEFVEETGVDALAVAIGTVHGVYKGEPK----- 187

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2558747382  79 adgklvpppLAFDVLDAVMEKLPgFPIVLHGSSsvpqdevdtinkyggklpdaiGIPEEELRKASKSAVCKINIDSDSRL 158
Cdd:COG0191   188 ---------LDFDRLKEIREAVP-VPLVLHGGS---------------------GVPDEEIREAIKLGVAKINIDTDLRL 236

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 2558747382 159 AMTAAVRKTLFEHPEEFDPRKYLGPARDNMEKLYKHKIEaVLGSKDKA 206
Cdd:COG0191   237 AFTAAVREYLAENPDKYDPRKYLKPAREAMKEVVKEKIR-LFGSAGKA 283
PRK09196 PRK09196
fructose-bisphosphate aldolase class II;
1-198 2.88e-77

fructose-bisphosphate aldolase class II;


Pssm-ID: 181691  Cd Length: 347  Bit Score: 235.24  E-value: 2.88e-77
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2558747382   1 VALTKKVVDYAHQYDVTVEGELGVL-------AGVED----EVSSDH-HTYTDPEEVIDFATRTGCDSLAISIGTSHGAY 68
Cdd:PRK09196  122 VDVTRKVVEMAHACGVSVEGELGCLgsletgmGGEEDghgaEGKLSHdQLLTDPEEAADFVKKTQVDALAIAIGTSHGAY 201

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2558747382  69 KFkpeqcTRNADGKLvpppLAFDVLDAVMEKLPGFPIVLHGSSSVPQDEVDTINKYGGKLPDAIGIPEEELRKASKSAVC 148
Cdd:PRK09196  202 KF-----TRKPTGDV----LAIDRIKEIHARLPNTHLVMHGSSSVPQELLDIINEYGGDMPETYGVPVEEIQEGIKHGVR 272

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 2558747382 149 KINIDSDSRLAMTAAVRKTLFEHPEEFDPRKYLGPARDNMEKLYKHKIEA 198
Cdd:PRK09196  273 KVNIDTDLRLAMTGAIRRFLAENPSEFDPRKYLKPAMEAMKKICKARYEA 322
TBP_aldolase_IIB cd00947
Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase ...
 1-202 3.99e-77

Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1,6-bisphosphate. There is an absolute requirement for a divalent metal ion, usually zinc, and in addition the enzymes are activated by monovalent cations such as Na+. The type A and type B Class II FBPA's differ in the presence and absence of distinct indels in the sequence that result in differing loop lengths in the structures.


Pssm-ID: 238477  Cd Length: 276  Bit Score: 232.42  E-value: 3.99e-77
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2558747382   1 VALTKKVVDYAHQYDVTVEGELGVLAGVEDEVSSDHHTYTDPEEVIDFATRTGCDSLAISIGTSHGAYKFkpeqctrnad 80
Cdd:cd00947   109 VAKTKEVVELAHAYGVSVEAELGRIGGEEDGVVGDEGLLTDPEEAEEFVEETGVDALAVAIGTSHGAYKG---------- 178

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2558747382  81 gklVPPPLAFDVLDAVMEKLPgFPIVLHGSSsvpqdevdtinkyggklpdaiGIPEEELRKASKSAVCKINIDSDSRLAM 160
Cdd:cd00947   179 ---GEPKLDFDRLKEIAERVN-VPLVLHGGS---------------------GIPDEQIRKAIKLGVCKININTDLRLAF 233

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 2558747382 161 TAAVRKTLFEHPEEFDPRKYLGPARDNMEKLYKHKIEaVLGS 202
Cdd:cd00947   234 TAALREYLAENPKEFDPRKYLAPAIEAVKEVVKHKME-LFGS 274
F_bP_aldolase pfam01116
Fructose-bisphosphate aldolase class-II;
1-205 4.26e-73

Fructose-bisphosphate aldolase class-II;


Pssm-ID: 460071  Cd Length: 276  Bit Score: 222.29  E-value: 4.26e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2558747382   1 VALTKKVVDYAHQYDVTVEGELGVLAGVEDEVSSDHHTYTDPEEVIDFATRTGCDSLAISIGTSHGAYKFKPEqctrnad 80
Cdd:pfam01116 113 IAITKEVVEYAHARGVSVEAELGRIGGEEDGVVVDEKLYTDPEEAAEFVEATGVDALAVAIGNVHGVYKPGPK------- 185

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2558747382  81 gklvpppLAFDVLDAVMEKLPgFPIVLHGSSsvpqdevdtinkyggklpdaiGIPEEELRKASKSAVCKINIDSDSRLAM 160
Cdd:pfam01116 186 -------LDFDRLKEIQEAVP-VPLVLHGGS---------------------GVPDEDIRKAIKLGVCKINIDTDLQLAF 236

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 2558747382 161 TAAVRKtlfeHPEEFDPRKYLGPARDNMEKLYKHKIEaVLGSKDK 205
Cdd:pfam01116 237 TAAVRE----YPPNKDPRKYLRPAEEAMKEVVKEKIR-LFGSAGK 276
PRK13399 PRK13399
fructose-bisphosphate aldolase class II;
1-198 5.64e-68

fructose-bisphosphate aldolase class II;


Pssm-ID: 184029  Cd Length: 347  Bit Score: 211.56  E-value: 5.64e-68
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2558747382   1 VALTKKVVDYAHQYDVTVEGELGVL-------AGVEDEVS-----SDHHTYTDPEEVIDFATRTGCDSLAISIGTSHGAY 68
Cdd:PRK13399  122 VDVTRRVTEMAHAVGVSVEGELGCLgsletgeAGEEDGVGaegklSHDQMLTDPDQAVDFVQRTGVDALAIAIGTSHGAY 201

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2558747382  69 KFkpeqcTRNADGKLvpppLAFDVLDAVMEKLPGFPIVLHGSSSVPQDEVDTINKYGGKLPDAIGIPEEELRKASKSAVC 148
Cdd:PRK13399  202 KF-----TRKPDGDI----LAIDRIEEIHARLPNTHLVMHGSSSVPQELQEIINAYGGKMKETYGVPVEEIQRGIKHGVR 272

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 2558747382 149 KINIDSDSRLAMTAAVRKTLFEHPEEFDPRKYLGPARDNMEKLYKHKIEA 198
Cdd:PRK13399  273 KVNIDTDIRLAMTGAIRKVLAEHPSEFDPRKALKPAMKAMTALCKQRFEA 322
fruc_bis_ald_ TIGR01859
fructose-1,6-bisphosphate aldolase, class II, various bacterial and amitochondriate protist; ...
 1-206 7.02e-63

fructose-1,6-bisphosphate aldolase, class II, various bacterial and amitochondriate protist; This model represents of one of several subtypes of the class II fructose-1,6-bisphosphate aldolase, an enzyme of glycolysis. The subtypes are split into several models to allow separation of a family of tagatose bisphosphate aldolases. This form is found in Gram-positive bacteria, a variety of Gram-negative, and in amitochondriate protists. The class II enzymes share homology with tagatose bisphosphate aldolase but not with class I aldolase. [Energy metabolism, Glycolysis/gluconeogenesis]


Pssm-ID: 130918  Cd Length: 282  Bit Score: 196.43  E-value: 7.02e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2558747382   1 VALTKKVVDYAHQYDVTVEGELGVLAGVEDEVSSDHHTYTDPEEVIDFATRTGCDSLAISIGTSHGayKFKPEqctrnad 80
Cdd:TIGR01859 114 LALTKKVVEIAHAKGVSVEAELGTLGGIEDGVDEKEAELADPDEAEQFVKETGVDYLAAAIGTSHG--KYKGE------- 184

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2558747382  81 gklvpPPLAFDVLDAVMEKLPgFPIVLHGSSsvpqdevdtinkyggklpdaiGIPEEELRKASKSAVCKINIDSDSRLAM 160
Cdd:TIGR01859 185 -----PGLDFERLKEIKELTN-IPLVLHGAS---------------------GIPEEQIKKAIKLGIAKINIDTDCRIAF 237

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 2558747382 161 TAAVRKTLFEHPEEFDPRKYLGPARDNMEKLYKHKIEaVLGSKDKA 206
Cdd:TIGR01859 238 TAAIRKVLTEKKDEYDPRKILGPAREAIKETVKEKMR-LFGSAGKA 282
FruBisAldo_II_B TIGR01521
fructose-bisphosphate aldolase, class II, Calvin cycle subtype; Members of this family are ...
 1-198 1.69e-57

fructose-bisphosphate aldolase, class II, Calvin cycle subtype; Members of this family are class II examples of the enzyme fructose-bisphosphate aldolase, an enzyme both of glycolysis and (in the opposite direction) of the Calvin cycle of CO2 fixation. A deep split separates the tightly conserved yeast/E. coli/Mycobacterium subtype (all species lacking the Calvin cycle) represented by model TIGR01520 from a broader group of aldolases that includes both tagatose- and fructose-bisphosphate aldolases. This model represents a distinct, elongated, very well conserved subtype within the latter group. Most species with this aldolase subtype have the Calvin cycle.


Pssm-ID: 130584  Cd Length: 347  Bit Score: 184.75  E-value: 1.69e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2558747382   1 VALTKKVVDYAHQYDVTVEGELGVL-------AGVED----EVSSDH-HTYTDPEEVIDFATRTGCDSLAISIGTSHGAY 68
Cdd:TIGR01521 120 VRVTAEVVAFAHAVGASVEGELGCLgsletgmGEAEDghgfEGVLDHsQLLTDPEEAADFVKKTKVDALAVAIGTSHGAY 199

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2558747382  69 KFkpeqcTRNADGKLvpppLAFDVLDAVMEKLPGFPIVLHGSSSVPQDEVDTINKYGGKLPDAIGIPEEELRKASKSAVC 148
Cdd:TIGR01521 200 KF-----TRKPTGEV----LAIQRIEEIHARLPDTHLVMHGSSSVPQEWLDIINEYGGEIKETYGVPVEEIVEGIKYGVR 270

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 2558747382 149 KINIDSDSRLAMTAAVRKTLFEHPEEFDPRKYLGPARDNMEKLYKHKIEA 198
Cdd:TIGR01521 271 KVNIDTDLRLASTAAFRRFAAQNPSEFDPRKFLKPTVEAMRDVCIARYEA 320
PRK12857 PRK12857
class II fructose-1,6-bisphosphate aldolase;
1-206 1.27e-55

class II fructose-1,6-bisphosphate aldolase;


Pssm-ID: 237235  Cd Length: 284  Bit Score: 178.00  E-value: 1.27e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2558747382   1 VALTKKVVDYAHQYDVTVEGELGVLAGVEDEVSSDHH--TYTDPEEVIDFATRTGCDSLAISIGTSHGAYKFKPEqctrn 78
Cdd:PRK12857  114 IALTKKVVEIAHAVGVSVEAELGKIGGTEDDITVDEReaAMTDPEEARRFVEETGVDALAIAIGTAHGPYKGEPK----- 188

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2558747382  79 adgklvpppLAFDVLDAVMEKLPgFPIVLHGSSsvpqdevdtinkyggklpdaiGIPEEELRKASKSAVCKINIDSDSRL 158
Cdd:PRK12857  189 ---------LDFDRLAKIKELVN-IPIVLHGSS---------------------GVPDEAIRKAISLGVRKVNIDTNIRE 237

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 2558747382 159 AMTAAVRKTLFEHPEEFDPRKYLGPARDNMEKLYKHKIEaVLGSKDKA 206
Cdd:PRK12857  238 AFVARLREVLEKNPDEIDPRKILGPAREAAKEVIREKIR-LFGSAGKA 284
cbbA TIGR00167
ketose-bisphosphate aldolase; This model is under revision. Proteins found by this model ...
 1-206 2.80e-51

ketose-bisphosphate aldolase; This model is under revision. Proteins found by this model include fructose-bisphosphate and tagatose-bisphosphate aldolase. [Energy metabolism, Glycolysis/gluconeogenesis]


Pssm-ID: 272938  Cd Length: 288  Bit Score: 167.11  E-value: 2.80e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2558747382   1 VALTKKVVDYAHQYDVTVEGELGVLAGVEDEVSSDHHT--YTDPEEVIDFATRTGCDSLAISIGTSHGAYKFKPEQctrn 78
Cdd:TIGR00167 117 IELTKKVVERAHKMGVSVEAELGTLGGEEDGVSVADESalYTDPEEAKEFVKLTGVDSLAAAIGNVHGVYKGEPKG---- 192

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2558747382  79 adgklvpppLAFDVLDAVmEKLPGFPIVLHGSSsvpqdevdtinkyggklpdaiGIPEEELRKASKSAVCKINIDSDSRL 158
Cdd:TIGR00167 193 ---------LDFERLEEI-QKYVNLPLVLHGGS---------------------GIPDEEIKKAISLGVVKVNIDTELQI 241

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 2558747382 159 AMTAAVRKTLFEHPEEFDPRKYLGPARDNMEKLYKHKIEaVLGSKDKA 206
Cdd:TIGR00167 242 AFAAAVRNYYAENKDYYDPRVWLRPGEKAMKEVVLEKIK-LFGSANKA 288
gatY PRK12737
tagatose-bisphosphate aldolase subunit GatY;
1-206 7.08e-49

tagatose-bisphosphate aldolase subunit GatY;


Pssm-ID: 183710  Cd Length: 284  Bit Score: 160.63  E-value: 7.08e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2558747382   1 VALTKKVVDYAHQYDVTVEGELGVLAGVEDE--VSSDHHTYTDPEEVIDFATRTGCDSLAISIGTSHGAYKFKPEqctrn 78
Cdd:PRK12737  114 IAIVKEVVEFCHRYDASVEAELGRLGGQEDDlvVDEKDAMYTNPDAAAEFVERTGIDSLAVAIGTAHGLYKGEPK----- 188

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2558747382  79 adgklvpppLAFDVLDAVMEKLpGFPIVLHGSSsvpqdevdtinkyggklpdaiGIPEEELRKASKSAVCKINIDSDSRL 158
Cdd:PRK12737  189 ---------LDFERLAEIREKV-SIPLVLHGAS---------------------GVPDEDVKKAISLGICKVNVATELKI 237

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 2558747382 159 AMTAAVRKTLFEHPEEFDPRKYLGPARDNMEKLYKHKIEaVLGSKDKA 206
Cdd:PRK12737  238 AFSDAVKKYFYENPKANDPRKYMTPGKAAMKEVVREKIK-VCGSEGKL 284
gatY PRK09195
tagatose-bisphosphate aldolase; Reviewed
 1-206 5.88e-47

tagatose-bisphosphate aldolase; Reviewed


Pssm-ID: 181690  Cd Length: 284  Bit Score: 155.67  E-value: 5.88e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2558747382   1 VALTKKVVDYAHQYDVTVEGELGVLAGVEDE--VSSDHHTYTDPEEVIDFATRTGCDSLAISIGTSHGAYKFKPEqctrn 78
Cdd:PRK09195  114 ISLVKEVVDFCHRFDVSVEAELGRLGGQEDDlqVDEADALYTDPAQAREFVEATGIDSLAVAIGTAHGMYKGEPK----- 188

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2558747382  79 adgklvpppLAFDVLDAVMEKLpGFPIVLHGSSsvpqdevdtinkyggklpdaiGIPEEELRKASKSAVCKINIDSDSRL 158
Cdd:PRK09195  189 ---------LDFDRLENIRQWV-NIPLVLHGAS---------------------GLPTKDIQQTIKLGICKVNVATELKI 237

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 2558747382 159 AMTAAVRKTLFEHPEEFDPRKYLGPARDNMEKLYKHKIeAVLGSKDKA 206
Cdd:PRK09195  238 AFSQALKNYLTEHPEANDPRHYLQPAKSAMKDVVSKVI-ADCGCEGKA 284
PRK05835 PRK05835
class II fructose-1,6-bisphosphate aldolase;
3-205 6.26e-47

class II fructose-1,6-bisphosphate aldolase;


Pssm-ID: 180280 [Multi-domain]  Cd Length: 307  Bit Score: 156.29  E-value: 6.26e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2558747382   3 LTKKVVDYAHQYDVTVEGELGVLAGVEDEVSSDHH--TYTDPEEVIDFATRTGCDSLAISIGTSHGAYKFKPEqctrnad 80
Cdd:PRK05835  116 LTSKVVKMAHNAGVSVEAELGRLMGIEDNISVDEKdaVLVNPKEAEQFVKESQVDYLAPAIGTSHGAFKFKGE------- 188

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2558747382  81 gklvpPPLAFDVLDAVmEKLPGFPIVLHGSSSVPQDEVDTINKYGGKLPDAIGIPEEELRKASKSAVCKINIDSDSRLAM 160
Cdd:PRK05835  189 -----PKLDFERLQEV-KRLTNIPLVLHGASAIPDDVRKSYLDAGGDLKGSKGVPFEFLQESVKGGINKVNTDTDLRIAF 262

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 2558747382 161 TAAVRKTLFEHPEEFDPRKYLGPARDNMEKLYKHKIEaVLGSKDK 205
Cdd:PRK05835  263 IAEVRKVANEDKSQFDLRKFFSPAQLALKNVVKERMK-LLGSANK 306
PRK08610 PRK08610
fructose-bisphosphate aldolase; Reviewed
 1-206 2.85e-40

fructose-bisphosphate aldolase; Reviewed


Pssm-ID: 181501  Cd Length: 286  Bit Score: 138.58  E-value: 2.85e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2558747382   1 VALTKKVVDYAHQYDVTVEGELGVLAGVEDEVSSDHHTYTDPEEVIDFATRTGCDSLAISIGTSHGAYKFKPEqctrnad 80
Cdd:PRK08610  117 VATTKKVVEYAHEKGVSVEAELGTVGGQEDDVVADGIIYADPKECQELVEKTGIDALAPALGSVHGPYKGEPK------- 189

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2558747382  81 gklvpppLAFDVLDAVMEKlPGFPIVLHGSSsvpqdevdtinkyggklpdaiGIPEEELRKASKSAVCKINIDSDSRLAM 160
Cdd:PRK08610  190 -------LGFKEMEEIGLS-TGLPLVLHGGT---------------------GIPTKDIQKAIPFGTAKINVNTENQIAS 240

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 2558747382 161 TAAVRKTLFEHPEEFDPRKYLGPARDNMEKLYKHKIEAvLGSKDKA 206
Cdd:PRK08610  241 AKAVRDVLNNDKEVYDPRKYLGPAREAIKETVKGKIKE-FGTSNRA 285
PRK08185 PRK08185
hypothetical protein; Provisional
 1-206 2.93e-38

hypothetical protein; Provisional


Pssm-ID: 181275  Cd Length: 283  Bit Score: 133.31  E-value: 2.93e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2558747382   1 VALTKKVVDYAHQYDVTVEGELGVLA--GVEDEVSSDHHTYTDPEEVIDFATRTGCDSLAISIGTSHGAYK--FKPEqct 76
Cdd:PRK08185  108 VALTKEVVELAHKVGVSVEGELGTIGntGTSIEGGVSEIIYTDPEQAEDFVSRTGVDTLAVAIGTAHGIYPkdKKPE--- 184

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2558747382  77 rnadgklvpppLAFDVLDAVMEKLpGFPIVLHGSSsvpqdevdtinkyggklpdaiGIPEEELRKASKSAVCKINIDSDS 156
Cdd:PRK08185  185 -----------LQMDLLKEINERV-DIPLVLHGGS---------------------ANPDAEIAESVQLGVGKINISSDM 231

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 2558747382 157 RLAMTAAVRKTLFEHPEEFDPRKYLGPARDNMEKLYKHKIeAVLGSKDKA 206
Cdd:PRK08185  232 KYAFFKKVREILSDNPSLYEPNQIYPSAIEAAKEVVRHKM-DLFNSTGKA 280
kbaY PRK12738
tagatose-bisphosphate aldolase subunit KbaY;
1-207 9.09e-37

tagatose-bisphosphate aldolase subunit KbaY;


Pssm-ID: 183711  Cd Length: 286  Bit Score: 129.77  E-value: 9.09e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2558747382   1 VALTKKVVDYAHQYDVTVEGELGVLAGVEDEVSSDHHT--YTDPEEVIDFATRTGCDSLAISIGTSHGAYKFKPEqctrn 78
Cdd:PRK12738  114 VKLVKSVVDFCHSQDCSVEAELGRLGGVEDDMSVDAESafLTDPQEAKRFVELTGVDSLAVAIGTAHGLYSKTPK----- 188

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2558747382  79 adgklvpppLAFDVLDAVMEKLpGFPIVLHGSSSVPqdevdtinkyggklpdaigipEEELRKASKSAVCKINIDSDSRL 158
Cdd:PRK12738  189 ---------IDFQRLAEIREVV-DVPLVLHGASDVP---------------------DEFVRRTIELGVTKVNVATELKI 237

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 2558747382 159 AMTAAVRKTLFEHPEEFDPRKYLGPARDNMEKLYKHKIEaVLGSKDKAL 207
Cdd:PRK12738  238 AFAGAVKAWFAENPQGNDPRYYMRVGMDAMKEVVRNKIN-VCGSANRIS 285
gatY PRK07998
class II aldolase;
1-207 1.25e-35

class II aldolase;


Pssm-ID: 181192  Cd Length: 283  Bit Score: 126.41  E-value: 1.25e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2558747382   1 VALTKKVVDYAHQYDVTVEGELGVLAGVEDEVSSDHHTYTDPEEVIDFATRTGCDSLAISIGTSHGAYKfkpeqctrnad 80
Cdd:PRK07998  114 IAFTKEAVDFAKSYGVPVEAELGAILGKEDDHVSEADCKTEPEKVKDFVERTGCDMLAVSIGNVHGLED----------- 182

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2558747382  81 gklvPPPLAFDVLDAVMEKLPgFPIVLHGSSsvpqdevdtinkyggklpdaiGIPEEELRKASKSAVCKINIDSDSRLAM 160
Cdd:PRK07998  183 ----IPRIDIPLLKRIAEVSP-VPLVIHGGS---------------------GIPPEILRSFVNYKVAKVNIASDLRKAF 236

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 2558747382 161 TAAVRKTLFEHPEEFDPRKYLGPARDNMEKLYKHKIEAVLGSKDKAL 207
Cdd:PRK07998  237 ITTVGKAYVNNHNEANLARVMAKAKQAVEEDVYSKIKMMNSNHRLVR 283
PRK07709 PRK07709
fructose-bisphosphate aldolase; Provisional
 1-206 2.49e-35

fructose-bisphosphate aldolase; Provisional


Pssm-ID: 169068  Cd Length: 285  Bit Score: 125.94  E-value: 2.49e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2558747382   1 VALTKKVVDYAHQYDVTVEGELGVLAGVEDEVSSDHHTYTDPEEVIDFATRTGCDSLAISIGTSHGAYKFKPEqctrnad 80
Cdd:PRK07709  117 VETTKKVVEYAHARNVSVEAELGTVGGQEDDVIAEGVIYADPAECKHLVEATGIDCLAPALGSVHGPYKGEPN------- 189

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2558747382  81 gklvpppLAFDVLDAVMEkLPGFPIVLHGSSsvpqdevdtinkyggklpdaiGIPEEELRKASKSAVCKINIDSDSRLAM 160
Cdd:PRK07709  190 -------LGFAEMEQVRD-FTGVPLVLHGGT---------------------GIPTADIEKAISLGTSKINVNTENQIEF 240

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 2558747382 161 TAAVRKTLFEHPEEFDPRKYLGPARDNMEKLYKHKIEAvLGSKDKA 206
Cdd:PRK07709  241 TKAVREVLNKDQEVYDPRKFIGPGRDAIKATVIGKIRE-FGSNGKA 285
Fbpase2_Halo NF041368
class II fructose-bisphosphate aldolase;
1-154 3.40e-28

class II fructose-bisphosphate aldolase;


Pssm-ID: 469259  Cd Length: 333  Bit Score: 108.19  E-value: 3.40e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2558747382   1 VALTKKVVDYAHQ--YDVTVEGELGVLAGVEDEVSSDHHTYTDPEEVIDFATRTGCDSLAISIGTSHGAYKfkpeqcTRN 78
Cdd:NF041368  128 VERTREVVEMVDAadEDVLVEAELGRIAGVEDGIETDEAFYTDPEQAVEFVDRTGCDLLAVSVGTQHGVAK------GRD 201

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2558747382  79 ADgklVPPPLAFDVLDAVMEKLPGFPIVLHGSSsvpqdevdtinkyggklpdaiGIPEEELRKASKSAVCKINIDS 154
Cdd:NF041368  202 LD---LRPDLAREIRDALRDHGLDTPLVVHGSS---------------------GLSPEQVRELLDAGVCKVNKNT 253
PRK06806 PRK06806
class II aldolase;
1-206 4.11e-27

class II aldolase;


Pssm-ID: 180705  Cd Length: 281  Bit Score: 104.07  E-value: 4.11e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2558747382   1 VALTKKVVDYAHQYDVTVEGELGVLAGVEDEVSSDHHTYTDPEEVIDFATRTGCDSLAISIGTSHGAYKFKPEqctrnad 80
Cdd:PRK06806  114 IQKTKEIVELAKQYGATVEAEIGRVGGSEDGSEDIEMLLTSTTEAKRFAEETDVDALAVAIGNAHGMYNGDPN------- 186

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2558747382  81 gklvpppLAFDVLDAVMEKLPgFPIVLHGSSsvpqdevdtinkyggklpdaiGIPEEELRKASKSAVCKINIDSDSRLAM 160
Cdd:PRK06806  187 -------LRFDRLQEINDVVH-IPLVLHGGS---------------------GISPEDFKKCIQHGIRKINVATATFNSV 237

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 2558747382 161 TAAVRKtLFEHPEEFDprkYLGPARDNMEKLY---KHKIEaVLGSKDKA 206
Cdd:PRK06806  238 ITAVNN-LVLNTPYSD---YFTYHQDVIKAAYenvKKHMQ-IFGSENKA 281
PRK07315 PRK07315
fructose-bisphosphate aldolase; Provisional
 1-206 6.54e-24

fructose-bisphosphate aldolase; Provisional


Pssm-ID: 180926  Cd Length: 293  Bit Score: 96.11  E-value: 6.54e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2558747382   1 VALTKKVVDYAHQYDVTVEGELGVLAGVEDEVSSDHHTYtdPEEVIDFATRTGCDSLAISIGTSHGAYkfkPEqctrNAD 80
Cdd:PRK07315  116 LKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGELA--PIEDAKAMVETGIDFLAAGIGNIHGPY---PE----NWE 186

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2558747382  81 GklvpppLAFDVLDAVMEKLPGFPIVLHGSSsvpqdevdtinkyggklpdaiGIPEEELRKASKSAVCKINIDSDSRLAM 160
Cdd:PRK07315  187 G------LDLDHLEKLTEAVPGFPIVLHGGS---------------------GIPDDQIQEAIKLGVAKVNVNTECQIAF 239

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2558747382 161 TAAVRKTL--FEHPEE-------FDPRKYLGPARDNMEKLYKHKIEaVLGSKDKA 206
Cdd:PRK07315  240 ANATRKFArdYEANEAeydkkklFDPRKFLAPGVKAIQASVEERID-VFGSANKA 293
PRK06801 PRK06801
ketose 1,6-bisphosphate aldolase;
1-151 1.24e-23

ketose 1,6-bisphosphate aldolase;


Pssm-ID: 180701  Cd Length: 286  Bit Score: 95.20  E-value: 1.24e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2558747382   1 VALTKKVVDYAHQYDVTVEGELGVLAGVED---EVSSDHHTYTDPEEVIDFATRTGCDSLAISIGTSHGAYKFKPEqctr 77
Cdd:PRK06801  114 VRQTREVVKMCHAVGVSVEAELGAVGGDEGgalYGEADSAKFTDPQLARDFVDRTGIDALAVAIGNAHGKYKGEPK---- 189

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2558747382  78 nadgklvpppLAFDVLDAVMEKLpGFPIVLHGSSsvpqdevdtinkyggklpdaiGIPEEELRKASKSAVCKIN 151
Cdd:PRK06801  190 ----------LDFARLAAIHQQT-GLPLVLHGGS---------------------GISDADFRRAIELGIHKIN 231
PLN02858 PLN02858
fructose-bisphosphate aldolase
 1-206 4.03e-14

fructose-bisphosphate aldolase


Pssm-ID: 215463 [Multi-domain]  Cd Length: 1378  Bit Score: 70.27  E-value: 4.03e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2558747382    1 VALTKKVVDYAHQYDVTVEGELGVLAGVEDEVSSDHH--TYTDPEEVIDFATRTGCDSLAISIGTSHGAYKfkpeqctrn 78
Cdd:PLN02858  1209 ISYTKSISSLAHSKGLMVEAELGRLSGTEDGLTVEEYeaKLTDVDQAKEFIDETGIDALAVCIGNVHGKYP--------- 1279

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2558747382   79 ADGklvpPPLAFDVLDAV----MEKlpGFPIVLHGSSsvpqdevdtinkyggklpdaiGIPEEELRKASKSAVCKINIDS 154
Cdd:PLN02858  1280 ASG----PNLRLDLLKELralsSKK--GVLLVLHGAS---------------------GLPESLIKECIENGVRKFNVNT 1332

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|..
gi 2558747382  155 DSRLAMTAAVRKtlfehPEEFDPRKYLGPARDNMEKLYKHKIEaVLGSKDKA 206
Cdd:PLN02858  1333 EVRTAYMEALSS-----PKKTDLIDVMSAAKEAMKAVVAEKLR-LFGSAGKA 1378
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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