NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|2559317374|ref|WP_304673902|]
View 

lactoferrin/transferrin family TonB-dependent receptor [Neisseria polysaccharea]

Protein Classification

lactoferrin/transferrin family TonB-dependent receptor( domain architecture ID 11493155)

lactoferrin/transferrin family TonB-dependent receptor similar to Neisseria meningitidis TbpA, an integral outer membrane protein component of the transferrin transport system that promotes iron release from transferrin

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
TonB-tbp-lbp TIGR01776
TonB-dependent lactoferrin and transferrin receptors; This family of TonB-dependent receptors ...
1-911 0e+00

TonB-dependent lactoferrin and transferrin receptors; This family of TonB-dependent receptors are responsible for import of iron from the mammalian iron carriers lactoferrin and transferrin across the outer membrane. These receptors are found only in bacteria which can infect mammals such as Moraxella, Mannheimia, Neisseria, Actinobacillus, Pasteurella, Haemophilus and Histophilus species. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


:

Pssm-ID: 273799 [Multi-domain]  Cd Length: 932  Bit Score: 1187.70  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374   1 MQQQHLFRLNILCLSLMTALPVY----AENVQAGQAQEKQLDTIQVKAKKQKTRRDNEVTGLGKLVKTADTLSKEQVLDI 76
Cdd:TIGR01776   2 KMKKHVLNLSILALSLLFATLSFqtadADSAKDTANQAVYLDEITVTATKVAHRRSNEVTGLGKVVKTAETLSKEQVLGI 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374  77 RDLTRYDPGIAVVEQGRGASSGYSIRGMDKNRVSLTVDGLAQIQSYTAQAALGGTrtaGSSGAINEIEYENVKAVEISKG 156
Cdd:TIGR01776  82 RDLTRYDPGISVVEQGRGASSGYSIRGVDKNRVAVTVDGIPQIQSYTSQGSRSGT---AGSGAINEIEYENVRSVEISKG 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 157 SNSVEQGSGALAGSVAFQTKTADDVIGEGRQWGIQSKTAYSGKNRGLTQSIALAGRIGGAEALLIHTGRRAGEIRAHEAA 236
Cdd:TIGR01776 159 ANSSEYGSGALGGSVAFRTKDASDIIKPGKHWGLQSKTAYSSKNRHFLQSLAAAGKAGGFEGLVIYTKRRGKETKAHGDA 238
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 237 GRGVQSFNRLVPVEDT-----NQYANFIVEEECESRNYETCKANPK-KDVVGKDERQ-----------TVSTRDYTGPNR 299
Cdd:TIGR01776 239 NKGVQSIDRLDAFEQKydlrpPQGRSFIVENECASLDCAPCAQYGYvYDNQLSDEEKaqvlasryrheQVSAKDYTGENR 318
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 300 FLADPLSYESRSWLFRPGFRFeNKRHYIGGILERTQQTFDTRDMTVPAFLTKEvfDANK-NPLPGYGKYAGDHKYGGLFT 378
Cdd:TIGR01776 319 LLPNPLDYRSDSWLAKLGYHL-NNRHYVGGVLEDTKQRYDIRDMTEPAYLGLS--DAVKgRLKNGGGIYLGDNYLEGLNF 395
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 379 KVENDAEVGAEYGTGVFYDETHTKSRYGLEYVYTNADKDTWADYARLSYDRQDIGLDNHFQQTHCSA-DGSDKYCRPSAD 457
Cdd:TIGR01776 396 NAGPASFKGLRYARGKFFDERHTKRRYGLEYRYKNEDYDRWLDTAKLSLDKQKIELRSRLQELHCSQyPKVDKNCRPSLD 475
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 458 KPSSYYKSDRVIYGESHKLLQAAFKKSFDTAKIRHNLSVNLGFDRFGSNLRHQDYYSQSADRAYlpktthpdnPKISLNG 537
Cdd:TIGR01776 476 KPYSFYKNDRNHYKEKHNVIQAEFDKSFDLGGGRHHLNLLLGYDKFKSQLSRHDYRRQNAVGTY---------ESIRGDE 546
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 538 SQDKPYWVSIGGGNVKKKELC-LSSSNNYAD-CTPRSINGKSYYAAVRDNVRLGRWADVGAGLRYDYRSTHSDDGSVSTG 615
Cdd:TIGR01776 547 PKQNPYKYRLGKATIVKNSLCrYSETNGYANcCEPRKIKGSNHYISLNDNFTIGKYVDLGLGGRYDKHNFKSTDRLVYSG 626
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 616 THRTLSWNVGIVLKPANWLDLTYRASTGFRLPSFAEMYGWRSGDKI--------KAVKIDPEKSFNKEAGIVFKGDFGNL 687
Cdd:TIGR01776 627 TYRNLSWNFGIVVKPTPFFSLSYRASTGFRVPSFYELYGERRGKASkknvqqflRTPDLKPEKSLNHEIGARFKGDFGHL 706
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 688 EASWFNNAYRDLIVRGYEAQIKN--GKEEAKGDPAYLNAQSARITGINILGKIDWNGVWDKLPEGWYSTFAYNRVRVRDI 765
Cdd:TIGR01776 707 EVSYFRNRYKDMIAEAPETRTDNeaGQTYGYCDHNYHNAQNAVLKGINILGKLDLNGVASKLPDGLYSTLAYNRIKVKEV 786
                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 766 KKRADRTDIQSHLFDAIQPSRYVIGLGYDQPEGKWGVNGMLTYSKAKEITELLGSRALLNGNSRNTKATARRTRPWYIVD 845
Cdd:TIGR01776 787 KNRAGRLDVRSPLLDAIQPARYVVGLGYDHPSQKWGINLTLTYSKAKNPDELAGTEYLGNGNVVKQTATKKLSRSWYTLD 866
                         890       900       910       920       930       940
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2559317374 846 VSGYYTIKKHFTLRAGVYNLLNHRYVTWENVRQTAGGAVNQHKNVGVYNRYAAPGRNYTFSLEMRF 911
Cdd:TIGR01776 867 VTGYVNLKKNLTLRAGVYNLFNYRYTTWESVRQTASNAVNQHTGVSNYNRYAAPGRNYSLSLEMKF 932
 
Name Accession Description Interval E-value
TonB-tbp-lbp TIGR01776
TonB-dependent lactoferrin and transferrin receptors; This family of TonB-dependent receptors ...
1-911 0e+00

TonB-dependent lactoferrin and transferrin receptors; This family of TonB-dependent receptors are responsible for import of iron from the mammalian iron carriers lactoferrin and transferrin across the outer membrane. These receptors are found only in bacteria which can infect mammals such as Moraxella, Mannheimia, Neisseria, Actinobacillus, Pasteurella, Haemophilus and Histophilus species. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273799 [Multi-domain]  Cd Length: 932  Bit Score: 1187.70  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374   1 MQQQHLFRLNILCLSLMTALPVY----AENVQAGQAQEKQLDTIQVKAKKQKTRRDNEVTGLGKLVKTADTLSKEQVLDI 76
Cdd:TIGR01776   2 KMKKHVLNLSILALSLLFATLSFqtadADSAKDTANQAVYLDEITVTATKVAHRRSNEVTGLGKVVKTAETLSKEQVLGI 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374  77 RDLTRYDPGIAVVEQGRGASSGYSIRGMDKNRVSLTVDGLAQIQSYTAQAALGGTrtaGSSGAINEIEYENVKAVEISKG 156
Cdd:TIGR01776  82 RDLTRYDPGISVVEQGRGASSGYSIRGVDKNRVAVTVDGIPQIQSYTSQGSRSGT---AGSGAINEIEYENVRSVEISKG 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 157 SNSVEQGSGALAGSVAFQTKTADDVIGEGRQWGIQSKTAYSGKNRGLTQSIALAGRIGGAEALLIHTGRRAGEIRAHEAA 236
Cdd:TIGR01776 159 ANSSEYGSGALGGSVAFRTKDASDIIKPGKHWGLQSKTAYSSKNRHFLQSLAAAGKAGGFEGLVIYTKRRGKETKAHGDA 238
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 237 GRGVQSFNRLVPVEDT-----NQYANFIVEEECESRNYETCKANPK-KDVVGKDERQ-----------TVSTRDYTGPNR 299
Cdd:TIGR01776 239 NKGVQSIDRLDAFEQKydlrpPQGRSFIVENECASLDCAPCAQYGYvYDNQLSDEEKaqvlasryrheQVSAKDYTGENR 318
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 300 FLADPLSYESRSWLFRPGFRFeNKRHYIGGILERTQQTFDTRDMTVPAFLTKEvfDANK-NPLPGYGKYAGDHKYGGLFT 378
Cdd:TIGR01776 319 LLPNPLDYRSDSWLAKLGYHL-NNRHYVGGVLEDTKQRYDIRDMTEPAYLGLS--DAVKgRLKNGGGIYLGDNYLEGLNF 395
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 379 KVENDAEVGAEYGTGVFYDETHTKSRYGLEYVYTNADKDTWADYARLSYDRQDIGLDNHFQQTHCSA-DGSDKYCRPSAD 457
Cdd:TIGR01776 396 NAGPASFKGLRYARGKFFDERHTKRRYGLEYRYKNEDYDRWLDTAKLSLDKQKIELRSRLQELHCSQyPKVDKNCRPSLD 475
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 458 KPSSYYKSDRVIYGESHKLLQAAFKKSFDTAKIRHNLSVNLGFDRFGSNLRHQDYYSQSADRAYlpktthpdnPKISLNG 537
Cdd:TIGR01776 476 KPYSFYKNDRNHYKEKHNVIQAEFDKSFDLGGGRHHLNLLLGYDKFKSQLSRHDYRRQNAVGTY---------ESIRGDE 546
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 538 SQDKPYWVSIGGGNVKKKELC-LSSSNNYAD-CTPRSINGKSYYAAVRDNVRLGRWADVGAGLRYDYRSTHSDDGSVSTG 615
Cdd:TIGR01776 547 PKQNPYKYRLGKATIVKNSLCrYSETNGYANcCEPRKIKGSNHYISLNDNFTIGKYVDLGLGGRYDKHNFKSTDRLVYSG 626
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 616 THRTLSWNVGIVLKPANWLDLTYRASTGFRLPSFAEMYGWRSGDKI--------KAVKIDPEKSFNKEAGIVFKGDFGNL 687
Cdd:TIGR01776 627 TYRNLSWNFGIVVKPTPFFSLSYRASTGFRVPSFYELYGERRGKASkknvqqflRTPDLKPEKSLNHEIGARFKGDFGHL 706
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 688 EASWFNNAYRDLIVRGYEAQIKN--GKEEAKGDPAYLNAQSARITGINILGKIDWNGVWDKLPEGWYSTFAYNRVRVRDI 765
Cdd:TIGR01776 707 EVSYFRNRYKDMIAEAPETRTDNeaGQTYGYCDHNYHNAQNAVLKGINILGKLDLNGVASKLPDGLYSTLAYNRIKVKEV 786
                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 766 KKRADRTDIQSHLFDAIQPSRYVIGLGYDQPEGKWGVNGMLTYSKAKEITELLGSRALLNGNSRNTKATARRTRPWYIVD 845
Cdd:TIGR01776 787 KNRAGRLDVRSPLLDAIQPARYVVGLGYDHPSQKWGINLTLTYSKAKNPDELAGTEYLGNGNVVKQTATKKLSRSWYTLD 866
                         890       900       910       920       930       940
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2559317374 846 VSGYYTIKKHFTLRAGVYNLLNHRYVTWENVRQTAGGAVNQHKNVGVYNRYAAPGRNYTFSLEMRF 911
Cdd:TIGR01776 867 VTGYVNLKKNLTLRAGVYNLFNYRYTTWESVRQTASNAVNQHTGVSNYNRYAAPGRNYSLSLEMKF 932
ligand_gated_channel cd01347
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ...
64-911 8.06e-73

TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.


Pssm-ID: 238657 [Multi-domain]  Cd Length: 635  Bit Score: 252.37  E-value: 8.06e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374  64 TADTLSKEQVLDIRDLTRYDPGIAVVEQGRGASSGYSIRGMDKNRVSLTVDGLAQIQSYTaqaalggtrtaGSSGAINEI 143
Cdd:cd01347     6 TAEDIEKQPATSLADLLRRIPGVSVTRGGGGGGSTISIRGFGPDRTLVLVDGLPLASSNY-----------GRGVDLNTI 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 144 EYENVKAVEISKGSNSVEQGSGALAGSVAFQTKTADDVIGEGRQWGIQSKTAYSGKNRGLTQSIALAGRiGGAEALLIHT 223
Cdd:cd01347    75 PPELIERVEVLKGPSSALYGSGAIGGVVNIITKRPTDEFGGSVTAGYGSDNSGSSGGGGFDVSGALADD-GAFGARLYGA 153
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 224 GRRageiraheaagrgvqsfnrlvpvedtnqyanfiveeecesrnyetckanpkkdvvgkderqtvstRDYTGPNRFLAD 303
Cdd:cd01347   154 YRD-----------------------------------------------------------------GDGTIDGDGQAD 168
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 304 PLSYESRSWLFRPGFRFeNKRHYIGGILERTQQTFDTRDMTVPAFLTKevfDANKNPLPGYGKYAGDHKYGGLFTKVENd 383
Cdd:cd01347   169 DSDEERYNVAGKLDWRP-DDDTRLTLDAGYQDQDADGPGGTLPANGTG---SSLGGGPSSNTNGDRDWDYRDRYRKRAS- 243
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 384 aevgaeYGTGVFYDETHTKSRYGLEYVYTNADKDTWADYARLSYDRQDIGLDnhfqqthcsadgsdkycrpsadkpSSYY 463
Cdd:cd01347   244 ------LGLEHDLNDTGWTLRANLSYSYTDNDGDPLILNGGNNAAGGDLGRS------------------------GYSS 293
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 464 KSDRVIYGeshklLQAAFKKSFDTAKIRHNLSVNLGFDRFGSNlrhqdyysqsadraylpktthpdnpkislngsqdkpy 543
Cdd:cd01347   294 ERDTTQLG-----FDAGLNAPFGTGPVAHTLTLGVEYRREELD------------------------------------- 331
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 544 wvsigggnvkkkelclsssnnyadctprsINGKSYYAAvrDNVRLGRWADVGAGLRYDYRSTHSDD----GSVSTGTHRT 619
Cdd:cd01347   332 -----------------------------EKQTALYAQ--DTIELTDDLTLTLGLRYDHYDQDSKDtiagGTTAKKSYSH 380
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 620 LSWNVGIVLKPANWLDLTYRASTGFRLPSFAEMYGWRSGDKIKAV---KIDPEKSFNKEAGIVFK-GDFGNLEASWFNNA 695
Cdd:cd01347   381 WSPSLGLVYKLTDGLSLYASYSQGFRAPSLGELYGGGSHGGTAAVgnpNLKPEKSKQYELGLKYDpGDGLTLSAALFRID 460
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 696 YRDLIVRGYEAQIKNGKEeakgdpAYLNAQSARITGINILGKIDWNGVWdklpeGWYSTFAYNRVRVRDikkraDRTDIQ 775
Cdd:cd01347   461 IKNEIVSTPTNTGLGLVT------VYVNGGKARIRGVELEASYDLTDGL-----GLTGSYTYTDTEVKR-----TDGATT 524
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 776 SHLFDAIQPSRYVIGLGYDQPEGKWGVNGMLTYSKAKEITEllgsrallngnsrNTKATARRTRPWYIVDVSGYYTIKKH 855
Cdd:cd01347   525 GNRLPGIPKHTANLGLDYELPDEGLTAGGGVRYRGKQYADT-------------ANGNNTVKVPGYTLVDLSASYQFTKN 591
                         810       820       830       840       850
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2559317374 856 FTLRAGVYNLLNHRYVTWENVRQTAggavnqhknvgvYNRYAAPGRNYTFSLEMRF 911
Cdd:cd01347   592 LTLRLGVNNLFDKDYYTSLSVRGSG------------LYGYYGPGRTYYLSVSYKF 635
TonB_dep_Rec pfam00593
TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
561-910 9.10e-39

TonB dependent receptor; This model now only covers the conserved part of the barrel structure.


Pssm-ID: 395474 [Multi-domain]  Cd Length: 475  Bit Score: 151.08  E-value: 9.10e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 561 SSNNYADCTPRSINGKSYYAAVRDNVRL-GRWaDVGAGLRYDYRSTHSDDGSVSTG----THRTLSWNVGIVLKPANWLD 635
Cdd:pfam00593 158 DPANPSSSSYSDTTTDSYGLYLQDNIKLtDRL-TLTLGLRYDHYSTDGDDGNGGGDnfsrSYSAFSPRLGLVYKPTDNLS 236
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 636 LTYRASTGFRLPSFAEMYGWRSGDKIKAV-----KIDPEKSFNKEAGIVFKGDFGNLEASWFNNAYRDLIVRGYEAQIKN 710
Cdd:pfam00593 237 LYASYSRGFRAPSLGELYGSGSGGGGGAVaggnpDLKPETSDNYELGLKYDDGRLSLSLALFYIDIKNLITSDPDGPGLG 316
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 711 GkeeakGDPAYLNAQSARITGINILGKIDwngVWDKLpeGWYSTFAYNRvrvrdiKKRADRTDIQSHLFDAIQPSRYVIG 790
Cdd:pfam00593 317 G-----TVYTYTNVGKARIRGVELELSGR---LWGLG--LSGGGYTYTD------ADDDADADDTGNPLPNVPRHTANLG 380
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 791 LGYDQPEGKWGVNGMLTYSkakeiteLLGSRALLNGNSrntkatARRTRPWYIVDVSGYYTIKKHFTLRAGVYNLLNHRY 870
Cdd:pfam00593 381 LTYDFPLGGWGARLGARYV-------GSGERRYGDAAN------TFKTPGYTLVDLSAGYRLNKNLTLRLGVNNLFDKYY 447
                         330       340       350       360
                  ....*....|....*....|....*....|....*....|
gi 2559317374 871 VTWENVrqtaggavnqhkNVGVYNRYAAPGRNYTFSLEMR 910
Cdd:pfam00593 448 KRYYSS------------GGGNLGGYPGPGRTFYLGLSYK 475
FepA COG4771
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and ...
11-859 1.38e-34

Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism];


Pssm-ID: 443803 [Multi-domain]  Cd Length: 612  Bit Score: 140.76  E-value: 1.38e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374  11 ILCLSLMTALPVYAENVQAGQAQEKQLDTIQVKAKKQKTRRDNevTGLGKLVKTADTLSKEQVLDIRDLTRYDPGIAVVE 90
Cdd:COG4771     1 LLLASLLLLLALAAQAADALAEDATELEEVVVTATRTEQSLSD--APASVSVITAEEIEKLGATDLADALRLLPGVSVTR 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374  91 Q-GRGASSGYSIRGMDKNRVSLTVDGLAQIqsytaqaalggTRTAGSSGAINEIEYENVKAVEISKGSNSVEQGSGALAG 169
Cdd:COG4771    79 SgGRGGSSGISIRGLGGDRVLVLIDGVPVN-----------NPALGGGGDLSYIPPDDIERIEVIRGPASALYGSDAIGG 147
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 170 SVAFQTKTADDvigegrQWGIQSKTAYSGKNRGLTQ-SIALAGRIGGAEALLIHTGRRAGEiraheaagrgvqsfnrlvp 248
Cdd:COG4771   148 VINIITKKPTD------ELEGSVSLGYGSNGNGTYSgSLSLGGPGDKLSFLLSGSYRDRDG------------------- 202
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 249 vedtnqyanfiveeecesrnyetckanpkkdvvgkderqtvsTRDYTGPNRflADPLSYESRSWLFRPGFRFeNKRHYIG 328
Cdd:COG4771   203 ------------------------------------------YLDYRNGGF--VGNSGYERYNLNAKLGYRL-SDNHRLS 237
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 329 GILERTQQTFDTRDMTVPAFLTKEVFDANKNPLPGYGKYAGDHKYgglftkvendaEVGAEYGTGVFYDETHTKSRYGLE 408
Cdd:COG4771   238 LSGGYSRQDRDGGPPTLGDTEISSDNAGDRDTTTDRGNYSLRYNG-----------DLGDNLDLSLYYSRTDRDSTNGSL 306
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 409 YVYTNADKDTwadyarlsyDRQDIGLDNHFQQThcsadgsdkycrpsadkpssyyksdrviYGESHKLlqaafkksfdta 488
Cdd:COG4771   307 GGSTGSFSDS---------DDTTYGLELDLTYP----------------------------LGGNHTL------------ 337
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 489 kirhnlsvnlgfdRFGSNLRHQDYYSQSADraylpktthpdnpkislngsqdkpywvsigggnvkkkelclsssnnyadc 568
Cdd:COG4771   338 -------------TLGAEYRYDDLDSSSFL-------------------------------------------------- 354
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 569 TPRSINGKSYYAAVRDNVRLGRWADVGAGLRYDYRSTHSDDGSVstgthrTLSWNVGIVLKPANWLDLTYRASTGFRLPS 648
Cdd:COG4771   355 GGADASRDTYGLFAQDEWKLTDKLTLTAGLRYDYYSTFGASNYT------AFSPRLGLRYDLSDNLTLRASYGRGFRAPS 428
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 649 FAEMYGWRSGDKIKAV----KIDPEKSFNKEAGIVFKGDFG--NLEASWFNNAYRDLIVRGYEAQIKNGKEeakgdpAYL 722
Cdd:COG4771   429 LAELYGSGTGTPGRYVlgnpDLKPETSDNYELGLEYRLGNGglSLSLTGFYTDIKDLIVLVPVGPGPGDVL------QYE 502
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 723 NAQSARITGINILGKIDWNGVWDklpegWYSTFAYNRVRVRDIKKRADRTDIQSHLFdaiqpsryVIGLGYDQPEGKWGV 802
Cdd:COG4771   503 NVGKARTYGLELELKYRLGKGLT-----LTASYTYLDSKIDDGDTGEPLPNVPPHKA--------NLGLDYRLPKWWLLL 569
                         810       820       830       840       850
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2559317374 803 NGMLTYSKAKEitellgsrallngnSRNTKATARRTRPWYIVDVSGYYTIKKHFTLR 859
Cdd:COG4771   570 LLTRYYGGRYV--------------TPPSGRLEGYTPGYTLLDLRASYKLTKNLTLS 612
PRK13524 PRK13524
FepA family TonB-dependent siderophore receptor;
570-911 8.94e-11

FepA family TonB-dependent siderophore receptor;


Pssm-ID: 237410 [Multi-domain]  Cd Length: 744  Bit Score: 65.82  E-value: 8.94e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 570 PRSiNGKSYYAAVRDNVRLGRWADVGAGLRYDYRSTHSDDGSVSTGTHRTLSWNV----GI--VLKPANwldlTYRASTG 643
Cdd:PRK13524  426 PYS-KAEIFSLFAEDNMELTDSTMLTPGLRFDHHSIVGNNWSPSLNLSQGLGDDFtlkmGIarAYKAPN----LYQTNPN 500
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 644 FRLPSFAE-MYGWRSG-------DKIKAvkidpEKSFNKEAGIVFKGDFGNLEASWFNNAYRDLIVRGYE--AQIKNGKE 713
Cdd:PRK13524  501 YILYSKGQgCYASAGNgcylqgnDDLKA-----ETSVNKEIGLEFKRDGWLAGLTWFRNDYRNKIEAGYVpvGTNSVGKT 575
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 714 EAKgdpAYLNAQSARITGINILGKIDWNGVWDklpegWYSTFAYNrVRVRDiKKRADRTdiqshlfdAIQPsRYVIGLGY 793
Cdd:PRK13524  576 DIY---QWENVPKAVVEGLEGTLNVPVSETVN-----WTNNLTYM-LQSKN-KTTGDPL--------SIIP-EYTLNSTL 636
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 794 D-QPEGKWGVNGMLTY---SKAKEitellgsralLNGNSRNTKATARRTR-PWYIVDVSGYYTIKKHFTLRAGVYNLLNH 868
Cdd:PRK13524  637 SwQATEDLSLQSTFTWygkQKPKK----------YNYKGQPVTGSATKEVsPYSIVGLSATYDVTKNVSLTGGVDNLFDK 706
                         330       340       350       360
                  ....*....|....*....|....*....|....*....|...
gi 2559317374 869 RYVTWENVRQTaggaVNQHKNVGVYNrYAAPGRNYTFSLEMRF 911
Cdd:PRK13524  707 RLWREGNAQTT----GDLIAGAGAYT-YNEPGRTYYMSLNTHF 744
 
Name Accession Description Interval E-value
TonB-tbp-lbp TIGR01776
TonB-dependent lactoferrin and transferrin receptors; This family of TonB-dependent receptors ...
1-911 0e+00

TonB-dependent lactoferrin and transferrin receptors; This family of TonB-dependent receptors are responsible for import of iron from the mammalian iron carriers lactoferrin and transferrin across the outer membrane. These receptors are found only in bacteria which can infect mammals such as Moraxella, Mannheimia, Neisseria, Actinobacillus, Pasteurella, Haemophilus and Histophilus species. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273799 [Multi-domain]  Cd Length: 932  Bit Score: 1187.70  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374   1 MQQQHLFRLNILCLSLMTALPVY----AENVQAGQAQEKQLDTIQVKAKKQKTRRDNEVTGLGKLVKTADTLSKEQVLDI 76
Cdd:TIGR01776   2 KMKKHVLNLSILALSLLFATLSFqtadADSAKDTANQAVYLDEITVTATKVAHRRSNEVTGLGKVVKTAETLSKEQVLGI 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374  77 RDLTRYDPGIAVVEQGRGASSGYSIRGMDKNRVSLTVDGLAQIQSYTAQAALGGTrtaGSSGAINEIEYENVKAVEISKG 156
Cdd:TIGR01776  82 RDLTRYDPGISVVEQGRGASSGYSIRGVDKNRVAVTVDGIPQIQSYTSQGSRSGT---AGSGAINEIEYENVRSVEISKG 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 157 SNSVEQGSGALAGSVAFQTKTADDVIGEGRQWGIQSKTAYSGKNRGLTQSIALAGRIGGAEALLIHTGRRAGEIRAHEAA 236
Cdd:TIGR01776 159 ANSSEYGSGALGGSVAFRTKDASDIIKPGKHWGLQSKTAYSSKNRHFLQSLAAAGKAGGFEGLVIYTKRRGKETKAHGDA 238
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 237 GRGVQSFNRLVPVEDT-----NQYANFIVEEECESRNYETCKANPK-KDVVGKDERQ-----------TVSTRDYTGPNR 299
Cdd:TIGR01776 239 NKGVQSIDRLDAFEQKydlrpPQGRSFIVENECASLDCAPCAQYGYvYDNQLSDEEKaqvlasryrheQVSAKDYTGENR 318
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 300 FLADPLSYESRSWLFRPGFRFeNKRHYIGGILERTQQTFDTRDMTVPAFLTKEvfDANK-NPLPGYGKYAGDHKYGGLFT 378
Cdd:TIGR01776 319 LLPNPLDYRSDSWLAKLGYHL-NNRHYVGGVLEDTKQRYDIRDMTEPAYLGLS--DAVKgRLKNGGGIYLGDNYLEGLNF 395
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 379 KVENDAEVGAEYGTGVFYDETHTKSRYGLEYVYTNADKDTWADYARLSYDRQDIGLDNHFQQTHCSA-DGSDKYCRPSAD 457
Cdd:TIGR01776 396 NAGPASFKGLRYARGKFFDERHTKRRYGLEYRYKNEDYDRWLDTAKLSLDKQKIELRSRLQELHCSQyPKVDKNCRPSLD 475
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 458 KPSSYYKSDRVIYGESHKLLQAAFKKSFDTAKIRHNLSVNLGFDRFGSNLRHQDYYSQSADRAYlpktthpdnPKISLNG 537
Cdd:TIGR01776 476 KPYSFYKNDRNHYKEKHNVIQAEFDKSFDLGGGRHHLNLLLGYDKFKSQLSRHDYRRQNAVGTY---------ESIRGDE 546
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 538 SQDKPYWVSIGGGNVKKKELC-LSSSNNYAD-CTPRSINGKSYYAAVRDNVRLGRWADVGAGLRYDYRSTHSDDGSVSTG 615
Cdd:TIGR01776 547 PKQNPYKYRLGKATIVKNSLCrYSETNGYANcCEPRKIKGSNHYISLNDNFTIGKYVDLGLGGRYDKHNFKSTDRLVYSG 626
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 616 THRTLSWNVGIVLKPANWLDLTYRASTGFRLPSFAEMYGWRSGDKI--------KAVKIDPEKSFNKEAGIVFKGDFGNL 687
Cdd:TIGR01776 627 TYRNLSWNFGIVVKPTPFFSLSYRASTGFRVPSFYELYGERRGKASkknvqqflRTPDLKPEKSLNHEIGARFKGDFGHL 706
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 688 EASWFNNAYRDLIVRGYEAQIKN--GKEEAKGDPAYLNAQSARITGINILGKIDWNGVWDKLPEGWYSTFAYNRVRVRDI 765
Cdd:TIGR01776 707 EVSYFRNRYKDMIAEAPETRTDNeaGQTYGYCDHNYHNAQNAVLKGINILGKLDLNGVASKLPDGLYSTLAYNRIKVKEV 786
                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 766 KKRADRTDIQSHLFDAIQPSRYVIGLGYDQPEGKWGVNGMLTYSKAKEITELLGSRALLNGNSRNTKATARRTRPWYIVD 845
Cdd:TIGR01776 787 KNRAGRLDVRSPLLDAIQPARYVVGLGYDHPSQKWGINLTLTYSKAKNPDELAGTEYLGNGNVVKQTATKKLSRSWYTLD 866
                         890       900       910       920       930       940
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2559317374 846 VSGYYTIKKHFTLRAGVYNLLNHRYVTWENVRQTAGGAVNQHKNVGVYNRYAAPGRNYTFSLEMRF 911
Cdd:TIGR01776 867 VTGYVNLKKNLTLRAGVYNLFNYRYTTWESVRQTASNAVNQHTGVSNYNRYAAPGRNYSLSLEMKF 932
TonB-hemlactrns TIGR01786
TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; This model ...
38-911 0e+00

TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; This model represents a family of TonB-dependent outer membrane receptor/transporters acting on iron-containing proteins such as hemoglobin, transferrin and lactoferrin. Two subfamily models with a narrower scope are contained within this model, the heme/hemoglobin receptor family protein model (TIGR01785) and the transferrin/lactoferrin receptor family model (TIGR01776). Accessions which score above trusted to this model while not scoring above trusted to the more specific models are most likely to be hemoglobin transporters. Nearly all of the species containing trusted hits to this model have access to hemoglobin, transferrin or lactoferrin or related proteins in their biological niche. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273808 [Multi-domain]  Cd Length: 715  Bit Score: 571.28  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374  38 DTIQVKAKKQ--KTRRDNEVTGLGKLVKTADTLSKEQVLDIRDLTRYDPGIAVVEQGRGASSGYSIRGMDKNRVSLTVDG 115
Cdd:TIGR01786   1 DTITVTATRTadPQRRDLSVTPASVSVISREQLKSQQVRNLRDLLRYEPGVSVVEGGRGGSQGINIRGLDKNRVAVLVDG 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 116 LAQIQSYTAQAALggtrtagsSGAINEIEYENVKAVEISKGSNSVEQGSGALAGSVAFQTKTADDVIGEGRQWGIQSKTA 195
Cdd:TIGR01786  81 IRQNTSYGGQGST--------FYAINSIDPELIKSIEIVKGASSSLYGSGALGGVVAFRTKDAADLLKPGKDLGGLSKLG 152
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 196 YSGKNRGLTQSIALAGRIGGAEALLIHTGRRAGEIRAHEAAGRGVQSfnrlvpvedtnqyanfiveeecesrnyetckan 275
Cdd:TIGR01786 153 YSSANNRFTQSVAAAGRNDDVDALVQATYRRGHELKNGNKANIGNES--------------------------------- 199
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 276 pkkdvvgkderqtvstrdytgpNRFLADPLSYESRSWLFRPGFRFeNKRHYIGGILERTQQTFDTRDMTVPAFLTKEvfd 355
Cdd:TIGR01786 200 ----------------------KRSKPNPSDYKSQSFLAKLGWQL-NDAHRLGLSLEYTQTDYDEPEMTNTSYLTKP--- 253
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 356 aNKNPLPgygkyagdhkygglftkvendaevgaeYGTGVFYDETHTKSRYGLEYVYTNADkdTWADYARLSYDRQDIGLD 435
Cdd:TIGR01786 254 -LGAPLL---------------------------SSTVVLGDSKTRDRRTGLDYELNPDN--SWLDTVKLALDKQYIQLY 303
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 436 NHFQQTHCSadgsdkyCRPSADKPSSYYKSDRVIYGEshkllqaaFKKSFDTAKIRHNLSVNLGFDRFGSNLRHQDYYSQ 515
Cdd:TIGR01786 304 NYLNATSAS-------DYPGVDKNGRYKDKYDYYTLG--------FDTNNKIEFSVHSLSLTYGLDRFKDKVSTGDSRRN 368
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 516 SADRAYLPKTTHPDNPKISlngsqdkpywvsigggnvkkkelclsssnnyadctprsinGKSYYAAVRDNVRLGRWADVG 595
Cdd:TIGR01786 369 LPTAAYNLYGYEGENRPVK----------------------------------------GSNFGLFLQDNIKLGDWLSLS 408
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 596 AGLRYDYRSTH-----SDDGSVSTGTHRTLSWNVGIVLKPANWLDLTYRASTGFRLPSFAEMYGWRSGDKIKAVKI---- 666
Cdd:TIGR01786 409 AGLRYDHYKTDpkadeSKDYGAISKTYSRWSPSLGLTYKPTPWLTLYYSYSQGFRAPSFDELYGTGAHPGGGPYTFlpnp 488
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 667 --DPEKSFNKEAGIVFKGDFGNLEASWFNNAYRDLIVRGYEAQIKNGKEE--AKGDPAYLNAQSARITGINILGKIDWNG 742
Cdd:TIGR01786 489 nlKPETSKNWEIGINLHFDQLDFKVSYFRNDYKDFIDLGIGVTAKGNMAQvgSNTITNYVNIDNARIRGIELSGRYDLGS 568
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 743 VWDkLPEGWYSTFAYNRVRVRDIKKRAdrtdiqshLFDAIQPSRYVIGLGYDQPEGKWGVNGMLTYSKAKEITELLGSRA 822
Cdd:TIGR01786 569 FFS-GPDGWTTTLKYGYTKGKDSDTNP--------WLNAITPLKVVLGLGYDHPDEKWGVGLTLTFSGAKDAVDAYATYY 639
                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 823 LlngNSRNTKATARRTRPWYIVDVSGYYTIKKHFTLRAGVYNLLNHRYVTWENVRQTAGGAVnqhknvgvynRYAAPGRN 902
Cdd:TIGR01786 640 E---NGEAAKAGPLRTPSYTVVDLYGYYKPNKNLTLRFGVYNLLDRKYTTWESARQAGPLAT----------GYTAPGRN 706

                  ....*....
gi 2559317374 903 YTFSLEMRF 911
Cdd:TIGR01786 707 YKASVEYKF 715
ligand_gated_channel cd01347
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ...
64-911 8.06e-73

TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.


Pssm-ID: 238657 [Multi-domain]  Cd Length: 635  Bit Score: 252.37  E-value: 8.06e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374  64 TADTLSKEQVLDIRDLTRYDPGIAVVEQGRGASSGYSIRGMDKNRVSLTVDGLAQIQSYTaqaalggtrtaGSSGAINEI 143
Cdd:cd01347     6 TAEDIEKQPATSLADLLRRIPGVSVTRGGGGGGSTISIRGFGPDRTLVLVDGLPLASSNY-----------GRGVDLNTI 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 144 EYENVKAVEISKGSNSVEQGSGALAGSVAFQTKTADDVIGEGRQWGIQSKTAYSGKNRGLTQSIALAGRiGGAEALLIHT 223
Cdd:cd01347    75 PPELIERVEVLKGPSSALYGSGAIGGVVNIITKRPTDEFGGSVTAGYGSDNSGSSGGGGFDVSGALADD-GAFGARLYGA 153
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 224 GRRageiraheaagrgvqsfnrlvpvedtnqyanfiveeecesrnyetckanpkkdvvgkderqtvstRDYTGPNRFLAD 303
Cdd:cd01347   154 YRD-----------------------------------------------------------------GDGTIDGDGQAD 168
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 304 PLSYESRSWLFRPGFRFeNKRHYIGGILERTQQTFDTRDMTVPAFLTKevfDANKNPLPGYGKYAGDHKYGGLFTKVENd 383
Cdd:cd01347   169 DSDEERYNVAGKLDWRP-DDDTRLTLDAGYQDQDADGPGGTLPANGTG---SSLGGGPSSNTNGDRDWDYRDRYRKRAS- 243
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 384 aevgaeYGTGVFYDETHTKSRYGLEYVYTNADKDTWADYARLSYDRQDIGLDnhfqqthcsadgsdkycrpsadkpSSYY 463
Cdd:cd01347   244 ------LGLEHDLNDTGWTLRANLSYSYTDNDGDPLILNGGNNAAGGDLGRS------------------------GYSS 293
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 464 KSDRVIYGeshklLQAAFKKSFDTAKIRHNLSVNLGFDRFGSNlrhqdyysqsadraylpktthpdnpkislngsqdkpy 543
Cdd:cd01347   294 ERDTTQLG-----FDAGLNAPFGTGPVAHTLTLGVEYRREELD------------------------------------- 331
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 544 wvsigggnvkkkelclsssnnyadctprsINGKSYYAAvrDNVRLGRWADVGAGLRYDYRSTHSDD----GSVSTGTHRT 619
Cdd:cd01347   332 -----------------------------EKQTALYAQ--DTIELTDDLTLTLGLRYDHYDQDSKDtiagGTTAKKSYSH 380
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 620 LSWNVGIVLKPANWLDLTYRASTGFRLPSFAEMYGWRSGDKIKAV---KIDPEKSFNKEAGIVFK-GDFGNLEASWFNNA 695
Cdd:cd01347   381 WSPSLGLVYKLTDGLSLYASYSQGFRAPSLGELYGGGSHGGTAAVgnpNLKPEKSKQYELGLKYDpGDGLTLSAALFRID 460
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 696 YRDLIVRGYEAQIKNGKEeakgdpAYLNAQSARITGINILGKIDWNGVWdklpeGWYSTFAYNRVRVRDikkraDRTDIQ 775
Cdd:cd01347   461 IKNEIVSTPTNTGLGLVT------VYVNGGKARIRGVELEASYDLTDGL-----GLTGSYTYTDTEVKR-----TDGATT 524
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 776 SHLFDAIQPSRYVIGLGYDQPEGKWGVNGMLTYSKAKEITEllgsrallngnsrNTKATARRTRPWYIVDVSGYYTIKKH 855
Cdd:cd01347   525 GNRLPGIPKHTANLGLDYELPDEGLTAGGGVRYRGKQYADT-------------ANGNNTVKVPGYTLVDLSASYQFTKN 591
                         810       820       830       840       850
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2559317374 856 FTLRAGVYNLLNHRYVTWENVRQTAggavnqhknvgvYNRYAAPGRNYTFSLEMRF 911
Cdd:cd01347   592 LTLRLGVNNLFDKDYYTSLSVRGSG------------LYGYYGPGRTYYLSVSYKF 635
TonB_dep_Rec pfam00593
TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
561-910 9.10e-39

TonB dependent receptor; This model now only covers the conserved part of the barrel structure.


Pssm-ID: 395474 [Multi-domain]  Cd Length: 475  Bit Score: 151.08  E-value: 9.10e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 561 SSNNYADCTPRSINGKSYYAAVRDNVRL-GRWaDVGAGLRYDYRSTHSDDGSVSTG----THRTLSWNVGIVLKPANWLD 635
Cdd:pfam00593 158 DPANPSSSSYSDTTTDSYGLYLQDNIKLtDRL-TLTLGLRYDHYSTDGDDGNGGGDnfsrSYSAFSPRLGLVYKPTDNLS 236
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 636 LTYRASTGFRLPSFAEMYGWRSGDKIKAV-----KIDPEKSFNKEAGIVFKGDFGNLEASWFNNAYRDLIVRGYEAQIKN 710
Cdd:pfam00593 237 LYASYSRGFRAPSLGELYGSGSGGGGGAVaggnpDLKPETSDNYELGLKYDDGRLSLSLALFYIDIKNLITSDPDGPGLG 316
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 711 GkeeakGDPAYLNAQSARITGINILGKIDwngVWDKLpeGWYSTFAYNRvrvrdiKKRADRTDIQSHLFDAIQPSRYVIG 790
Cdd:pfam00593 317 G-----TVYTYTNVGKARIRGVELELSGR---LWGLG--LSGGGYTYTD------ADDDADADDTGNPLPNVPRHTANLG 380
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 791 LGYDQPEGKWGVNGMLTYSkakeiteLLGSRALLNGNSrntkatARRTRPWYIVDVSGYYTIKKHFTLRAGVYNLLNHRY 870
Cdd:pfam00593 381 LTYDFPLGGWGARLGARYV-------GSGERRYGDAAN------TFKTPGYTLVDLSAGYRLNKNLTLRLGVNNLFDKYY 447
                         330       340       350       360
                  ....*....|....*....|....*....|....*....|
gi 2559317374 871 VTWENVrqtaggavnqhkNVGVYNRYAAPGRNYTFSLEMR 910
Cdd:pfam00593 448 KRYYSS------------GGGNLGGYPGPGRTFYLGLSYK 475
TonB-hemin TIGR01785
TonB-dependent heme/hemoglobin receptor family protein; This model represents the ...
37-911 8.96e-35

TonB-dependent heme/hemoglobin receptor family protein; This model represents the TonB-dependent outer membrane heme/hemoglobin receptor/transporter found in bacteria which live in contact with animals (which contain hemoglobin or other heme-bearing globins) or legumes (which contain leghemoglobin). Some species having hits to this model such as Nostoc, Caulobacter and Chlorobium do not have an obvious source of hemoglobin-like proteins in their biological niche and so the possibility exists that they act on some other substance. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273807 [Multi-domain]  Cd Length: 665  Bit Score: 141.76  E-value: 8.96e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374  37 LDTIQVKAKKqkTRRDNEVTGLGKLVKTADTLSKEQVLDIRDLTRYDPGIAVVEQGRGASSGYSIRGMDKNRVSLTVDGL 116
Cdd:TIGR01785   1 LDTVTVTATR--TRQVLSEAPASVSVISGEQIESKQANNLADALNTVPGVDVTGGGRPPGQSINIRGLQDNRVLVVVDGA 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 117 AQiqsytaqaalgGTRTAGSSGAINEIEYENVKAVEISKGSNSVEQGSGALAGSVAFQTKTADDVIGEGRQWGIQSKTAY 196
Cdd:TIGR01785  79 RQ-----------NYQRGGAHNGSLFVDPELLKRIEIVKGPSSSLYGSGALGGVVAFRTKDAADLLRPGQLFGGLAKLSY 147
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 197 SGKNRGLTQSIALAGRIG-GAEALLIHTGRRAGEIRaheaagRGVQSfnrlvPVEDTnqyanfiveeecesrnyetckAN 275
Cdd:TIGR01785 148 GSNNNSFGGSVAVAGRLDdNLDALVAATYRDGGNYR------NGNKE-----EATNS---------------------AY 195
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 276 PKKDVVGKDERQTVSTrdytgpNRFladPLSYesrswlfrpgFRFENKRhyiggilertqqtfdtrdmtvpafltkevfD 355
Cdd:TIGR01785 196 VQKNLLAKLGWQLDDA------QRL---EFSY----------FTTEGSL------------------------------D 226
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 356 ANKNPLPGygkyagDHKYGGLFTKVenDAEVGAEYGTGVFYDETHTKSRYgleyvytnadkdtwadyarlsydrqdigLD 435
Cdd:TIGR01785 227 EAQNSGPG------TEYVLGSSSTL--LASSTRDRSATLTYNWTPEDNPW----------------------------LD 270
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 436 NHFQQTHCSADgSDKYcrPSADKPSSYYKSDRVIYGeshklLQAAFKKSFDTAKIRHnlsVNLGFDRFGSNLRhqdyySQ 515
Cdd:TIGR01785 271 ATASLYYNRTE-NDND--RSARGVGREEGYQYTTYG-----ATLQNTSRFDVASWST---LTYGVDWMKDKRR-----TE 334
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 516 SADRaylpktthpdnpkislNGSQDKPYwvsigggnvkkkelclsssNNYadctprsiNGKSYYAAV--RDNVRL-GRWA 592
Cdd:TIGR01785 335 SFDP----------------NSVTTIVP-------------------NPP--------SAKEYFFGLflQDNIPLlDDRL 371
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 593 DVGAGLRYDYRSTHSDDG---SVSTGTHRTLSWNVGIVLKPANWLDLTYRASTGFRLPSFAEMY------GWRSGDKIKA 663
Cdd:TIGR01785 372 TLSAGLRYDHYKLSPKTTadtEAVDRSYSRWSPSLGLSYKPVDWLTLYASYSQGFRAPSIDELYgtgdhpGTPGGYTFAP 451
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 664 -VKIDPEKSFNKEAGIVFKGD---FGN----LEASWFNNAYRDLI--VRGYEAQIKNGkeeAKGDPAYLNAQSARITGIN 733
Cdd:TIGR01785 452 nPNLKPETSKTWELGANLSFDnllLDNdqlqFKVAYFYNDVKDFIdlTIGVTDNVTAG---MNNITQYVNIDGARIRGIE 528
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 734 ILGKIDWNgvwdklpeGWYSTFAYNRVRVRDIKKRAdrtdiqshLFDAIQPSRYVIGLGYDQPEGKWGVNGMLTYSKAKE 813
Cdd:TIGR01785 529 ASASYDAG--------LWATGLSYGYTIGKDQNTNQ--------WLSNIPPLKLVVTVGYRFPDRRLDLGAKAAYYERQS 592
                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 814 ItellgsrallNGNSRNTKATARRTRPWYIV-DVSGYY--TIKKHFTLRAGVYNLLNHRYVTWENVrqtaggavnqhknv 890
Cdd:TIGR01785 593 E----------SPTTEDVAANGLLTTPGYTVvDLYATYqpNAVKGLTVRFGVNNLTDRKYTPAQSV-------------- 648
                         890       900
                  ....*....|....*....|.
gi 2559317374 891 gvynRYAAPGRNYTFSLEMRF 911
Cdd:TIGR01785 649 ----PGAGPGRNFKGSVKYQF 665
FepA COG4771
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and ...
11-859 1.38e-34

Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism];


Pssm-ID: 443803 [Multi-domain]  Cd Length: 612  Bit Score: 140.76  E-value: 1.38e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374  11 ILCLSLMTALPVYAENVQAGQAQEKQLDTIQVKAKKQKTRRDNevTGLGKLVKTADTLSKEQVLDIRDLTRYDPGIAVVE 90
Cdd:COG4771     1 LLLASLLLLLALAAQAADALAEDATELEEVVVTATRTEQSLSD--APASVSVITAEEIEKLGATDLADALRLLPGVSVTR 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374  91 Q-GRGASSGYSIRGMDKNRVSLTVDGLAQIqsytaqaalggTRTAGSSGAINEIEYENVKAVEISKGSNSVEQGSGALAG 169
Cdd:COG4771    79 SgGRGGSSGISIRGLGGDRVLVLIDGVPVN-----------NPALGGGGDLSYIPPDDIERIEVIRGPASALYGSDAIGG 147
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 170 SVAFQTKTADDvigegrQWGIQSKTAYSGKNRGLTQ-SIALAGRIGGAEALLIHTGRRAGEiraheaagrgvqsfnrlvp 248
Cdd:COG4771   148 VINIITKKPTD------ELEGSVSLGYGSNGNGTYSgSLSLGGPGDKLSFLLSGSYRDRDG------------------- 202
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 249 vedtnqyanfiveeecesrnyetckanpkkdvvgkderqtvsTRDYTGPNRflADPLSYESRSWLFRPGFRFeNKRHYIG 328
Cdd:COG4771   203 ------------------------------------------YLDYRNGGF--VGNSGYERYNLNAKLGYRL-SDNHRLS 237
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 329 GILERTQQTFDTRDMTVPAFLTKEVFDANKNPLPGYGKYAGDHKYgglftkvendaEVGAEYGTGVFYDETHTKSRYGLE 408
Cdd:COG4771   238 LSGGYSRQDRDGGPPTLGDTEISSDNAGDRDTTTDRGNYSLRYNG-----------DLGDNLDLSLYYSRTDRDSTNGSL 306
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 409 YVYTNADKDTwadyarlsyDRQDIGLDNHFQQThcsadgsdkycrpsadkpssyyksdrviYGESHKLlqaafkksfdta 488
Cdd:COG4771   307 GGSTGSFSDS---------DDTTYGLELDLTYP----------------------------LGGNHTL------------ 337
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 489 kirhnlsvnlgfdRFGSNLRHQDYYSQSADraylpktthpdnpkislngsqdkpywvsigggnvkkkelclsssnnyadc 568
Cdd:COG4771   338 -------------TLGAEYRYDDLDSSSFL-------------------------------------------------- 354
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 569 TPRSINGKSYYAAVRDNVRLGRWADVGAGLRYDYRSTHSDDGSVstgthrTLSWNVGIVLKPANWLDLTYRASTGFRLPS 648
Cdd:COG4771   355 GGADASRDTYGLFAQDEWKLTDKLTLTAGLRYDYYSTFGASNYT------AFSPRLGLRYDLSDNLTLRASYGRGFRAPS 428
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 649 FAEMYGWRSGDKIKAV----KIDPEKSFNKEAGIVFKGDFG--NLEASWFNNAYRDLIVRGYEAQIKNGKEeakgdpAYL 722
Cdd:COG4771   429 LAELYGSGTGTPGRYVlgnpDLKPETSDNYELGLEYRLGNGglSLSLTGFYTDIKDLIVLVPVGPGPGDVL------QYE 502
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 723 NAQSARITGINILGKIDWNGVWDklpegWYSTFAYNRVRVRDIKKRADRTDIQSHLFdaiqpsryVIGLGYDQPEGKWGV 802
Cdd:COG4771   503 NVGKARTYGLELELKYRLGKGLT-----LTASYTYLDSKIDDGDTGEPLPNVPPHKA--------NLGLDYRLPKWWLLL 569
                         810       820       830       840       850
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2559317374 803 NGMLTYSKAKEitellgsrallngnSRNTKATARRTRPWYIVDVSGYYTIKKHFTLR 859
Cdd:COG4771   570 LLTRYYGGRYV--------------TPPSGRLEGYTPGYTLLDLRASYKLTKNLTLS 612
CirA COG1629
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];
37-879 1.38e-33

Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];


Pssm-ID: 441236 [Multi-domain]  Cd Length: 644  Bit Score: 138.04  E-value: 1.38e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374  37 LDTIQVKAkkQKTRRDNEVTGLGKLVKTADTLSKEQVLDIRDLTRYDPGIaVVEQGRGASSGYSIRGMD--KNRVSLTVD 114
Cdd:COG1629     1 LEEVVVTA--TRTDESLQDVPGSVSVISREQLEDQPATDLGDLLRRVPGV-SVTSAGGGAGQISIRGFGggGNRVLVLVD 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 115 GLAQiqsytaqaalggTRTAGSSGAINEIEYENVKAVEISKGSNSVEQGSGALAGSVAFQTKTADDvigegrQWGIQSKT 194
Cdd:COG1629    78 GVPL------------NDPSGGDGGLSYIDPEDIERVEVLRGPSSALYGSGALGGVINIVTKKPKD------GKGGEVSA 139
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 195 AYSGKNRGLTqSIALAGRIGGAEALLIHTGRRAGEIRaheaagrgvqsfnrlvpvedtnqyanfiveeecesrnyetcka 274
Cdd:COG1629   140 SYGSYGTYRA-SLSLSGGNGKLAYRLSASYRDSDGYR------------------------------------------- 175
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 275 npkkdvvgkderqtvstrdytgpnrflaDPLSYESRSWLFRPGFRFeNKRHYIGGILERTQQTFDTrdmtvPAFLTKEVF 354
Cdd:COG1629   176 ----------------------------DNSDSDRYNLRAKLGYQL-GDDTRLTLSASYSDSDQDS-----PGYLTLAAL 221
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 355 DANKNPLPGYGKYAGDHkygglftkvendaevgaeygtgvfydETHTKSRYGLEYVYTNADkDTWADYARLSYDRQDIGL 434
Cdd:COG1629   222 RPRGAMDDGTNPYSNDT--------------------------DDNTRDRYSLSLEYEHLG-DGLKLSASAYYRYDDTDL 274
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 435 DNHFQQTHCSADGSDkycrpsadkpSSYYKSDRVIYgeshkLLQAAFKKSFDTakiRHNLsvnlgfdRFGSNLRHQDYys 514
Cdd:COG1629   275 DSDFTPTPADGGTLE----------QTDFDNRTYGL-----ELRLTYDLGFGG---KHTL-------LVGLDYQRQDL-- 327
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 515 qsadraylpktthpdnpkislngsQDKPYWVSIGGGNVkkkelclsssNNYADCTPRSINGKSYYAAVRDNVRLGRWADV 594
Cdd:COG1629   328 ------------------------DGSGYPLDLGSGSL----------PTLTSGADDDGTTTSLALYAQDTYKLTDKLTL 373
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 595 GAGLRYDYRSTHSDD---GSVSTGTHRT---LSWNVGIVLKPANWLDLTYRASTGFRLPSFAEMYGWRSGDKIKAV-KID 667
Cdd:COG1629   374 TAGLRYDYVSYDVDDtvtGTDSASGSRSysaFSPSLGLTYQLSPNLSLYASYSRGFRAPTFGELYANGTDPYSVGNpDLK 453
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 668 PEKSFNKEAGIVFKGDFGNL--EASWFNNAYRDLIVRGYEAQikngkeeAKGDPAYL-NAQSARITGINILGKIDWNGVW 744
Cdd:COG1629   454 PETSTNYELGLRYRLLDGRLslSLALFYSDVDNEILSVPLPN-------DSGFSTYYtNAGKARSYGVELELSYQLTPGL 526
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 745 DklpegWYSTFAYNRVRVRDIKkrADRTDIQSHLFDAIQPSRYVIGLGYDQPEGkWGVNGMLTYSkakeitellGSRALl 824
Cdd:COG1629   527 S-----LNASYSYTDAKFDDDT--DGSADLDGNRLPGVPPLTANLGLTYEFPGG-WSLGLGVRYV---------GDRYL- 588
                         810       820       830       840       850
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2559317374 825 ngnsrNTKATARRTRPWYIVDVSGYYTIKKHFTLRAGVYNLLNHRYVTWENVRQT 879
Cdd:COG1629   589 -----DDANTQGAPGGYTLVDLGAGYRFGDNLTLSLGVDNLFDKKYATSLSVRAS 638
Fiu COG4774
Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism];
64-911 3.68e-22

Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism];


Pssm-ID: 443806 [Multi-domain]  Cd Length: 639  Bit Score: 102.26  E-value: 3.68e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374  64 TADTLSKEQVLDIRDLTRYDPGIAVVEQGRGASSGYSIRGMDkNRVSLTVDGLAQIQSYTaqaalggtrtagssgaineI 143
Cdd:COG4774    17 TRELIEDQGATSLADALRNVPGVTFGAGEGGNGDSFSIRGFS-ASGDIYVDGLRDPGQYR-------------------R 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 144 EYENVKAVEISKGSNSVEQGSGALAGSVAFQTKTA-DDVIGEGRQwgiqskTAYSGKNRGLTqsialagriggaeallIH 222
Cdd:COG4774    77 DTFNLERVEVLKGPASVLYGRGSPGGVINLVTKRPtDEPFTEVTL------TYGSDGQRRAT----------------LD 134
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 223 TGRRAGEirahEAAGRgvqsFNRLvpVEDTNQYanfiveeecesrnyetckanpkkdvvgkderqtvstRDYTgpnrfla 302
Cdd:COG4774   135 VNGPLGD----DLAYR----LNGM--YRDSDSY------------------------------------RDGV------- 161
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 303 dplsyESRSWLFRPGFRFenkrhyigGILERTQQTFD--------TRDMTVPAFltkevfdANKNPLPGygkyAGDHKYG 374
Cdd:COG4774   162 -----DNDRWGIAPSLTW--------RLGDRTRLTLDyeyqdddrTPDYGVPAV-------ANGRPVDV----DRSTFYG 217
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 375 glftkVENDaevgaeygtgvFYDETHTKSRYGLEYVYTnadkDTWADYARLSYDRQDIGLDNHFQQThcsADGSDKYCRp 454
Cdd:COG4774   218 -----QPDD-----------YSDSETDSATLRLEHDFN----DNWTLRNALRYSDYDRDYRNTYPTG---GNATGTVTR- 273
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 455 sadkpsSYYKSDRVIYGEShklLQAAFKKSFDTAKIRHNLSvnlgfdrFGSNLRHQDYYSQSADRAYLPKTTHPDNPkis 534
Cdd:COG4774   274 ------SAYRRDQDNDTLS---NQTDLTGKFDTGGVKHTLL-------AGVEYSREDSDNARYSGGGTAPTVNLYNP--- 334
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 535 lngsQDKPYWVSIGGGNVKKKelclSSSNNYAdctprsingksyyAAVRDNVRLGRWADVGAGLRYDYRSTHSDDGSVST 614
Cdd:COG4774   335 ----VYGAPVTGPTLGGADND----SRTDTTG-------------LYLQDTISLTDRWSLLAGLRYDRFDTDYTDRTTGA 393
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 615 GTHRT----LSWNVGIVLKPANWLDL--TYraSTGFRLPSFAEMYGwrsgdkIKAVKIDPEKSFNKEAGI---VFKGDFG 685
Cdd:COG4774   394 TTSSYddsaFSPRAGLVYKPTPNLSLyaSY--STSFNPGGGAPSLS------NAGQALDPEKSRQYEVGVkwdLLDGRLS 465
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 686 nLEASWF-----NNAYRDLIVRGYEAQIknGKEEAKGdpaylnaqsaritginilgkIDWNGVWdKLPEGW--YSTFAYN 758
Cdd:COG4774   466 -LTAALFriektNVRTTDPANPGVYVQT--GEQRSRG--------------------VELEATG-ELTPGWsvLAGYTYL 521
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 759 RVRVRDikkrADRTDIQSHlfDAIQPSRYVIGLG--YDQPEGKWGVNGMLTYSkakeitellGSRAllnGNSRNTkataR 836
Cdd:COG4774   522 DAEITK----SANAANVGN--RLPNVPRHSASLWttYDLPLPGLTLGGGVRYV---------GSRY---ADAANT----V 579
                         810       820       830       840       850       860       870
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2559317374 837 RTRPWYIVDVSGYYTIKKHFTLRAGVYNLLNHRYVTWenvrqtaggavnqhknVGVYNR-YAAPGRNYTFSLEMRF 911
Cdd:COG4774   580 KLPSYTRFDAGASYRLNKNLTLRLNVNNLTDKRYYAS----------------AYGSGYvTPGAPRTVLLSASYRF 639
FecA COG4772
Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];
18-911 4.70e-22

Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];


Pssm-ID: 443804 [Multi-domain]  Cd Length: 681  Bit Score: 101.93  E-value: 4.70e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374  18 TALPVYAENVQAG-QAQEKQLDTIQVKAKKQKTRRDNEVTGLGKLVkTADTLSKEQVLDIRDLTRYDPGIAVV-EQGRGA 95
Cdd:COG4772     3 RALAAALLLAAAAaAEAATTLETVVVTGSRAAEARLKDVPGSVSVV-DREELENQAATSLREVLRRVPGVNVQeEDGFGL 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374  96 SSGYSIRGMDKNRVS---LTVDGLAqiqsyTAQAALGgtrtAGSSGAINEIEyeNVKAVEISKGSNSVEQGSGALAGSVA 172
Cdd:COG4772    82 RPNIGIRGLGPRRSRgitLLEDGIP-----IAPAPYG----DPAAYYFPDLE--RMERIEVLRGAAALRYGPQTVGGAIN 150
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 173 FQTKTADDvigegrQWGIQSKTAYsGKNRGLTQSIALAGRIGGAEALLIHTGRRAGEIRAHEAAGRgvqsfnrlvpvedT 252
Cdd:COG4772   151 FVTRTIPT------AFGGELRVTG-GSFGYRRTHASVGGTVGNFGYLVEYSRKRGDGFRDNSGFDI-------------N 210
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 253 NQYANFiveeecesrnyetckanpkkdvvgkderqtvstrdytgpnrfladplsyesrswlfrpGFRFeNKRHYIGGILE 332
Cdd:COG4772   211 DFNAKL----------------------------------------------------------GYRL-SDRQELTLKFQ 231
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 333 RTQQTFDTrdmtvPAFLTKEVFDAN--KNPLPgYGKYAGDHKYGGLFTKVENDAEVGAEygTGVFYDETHTKSRYGLEYV 410
Cdd:COG4772   232 YYDEDANT-----PGGLTDAQFDADprQSYRP-ADQFDTRRTQLSLRYEHQLSDNTTLT--TTAYYNDFSRNWYIRQNTA 303
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 411 YTNADKDTWADYARlsyDRQDIGLDNHFQQThcsadgsdkycrpsadkpssyyksdrviygeshkllqaafkksFDTAKI 490
Cdd:COG4772   304 DPNTPGLGLRGNPR---GYRSYGIEPRLTHR-------------------------------------------FELGGV 337
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 491 RHNLSVnlGFdrfgsnlrhqDYYSQSADRaylpktthpdnpkislNGSQDKPYWVSIGGGNVkkkelclSSSNNYADctp 570
Cdd:COG4772   338 PHTLEV--GL----------RYHREEEDR----------------KQYVNTYGQGRSGAGLR-------RDRRFSAD--- 379
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 571 rsingkSYYAAVRDNVRL-GRWAdVGAGLRYDYRSTHSDD---GSVSTGTHRTLSWN-----VGIVLKPANWLDLTYRAS 641
Cdd:COG4772   380 ------ALAAYAQNRFELtGRLT-LTPGLRYEHIRRDRTDrysTRTGGDDSGSNSYSeflpgLGLLYQLTDNLQLYANVS 452
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 642 TGFRLPSFAEMYGWRSGDkikaVKIDPEKSFNKEAGIVFK-GDFGNLEASWFNNAYRDLIVRGYEAQikngkeeakGDPA 720
Cdd:COG4772   453 RGFEPPTFGDLAYGNGGN----PDLKPEKSWNYELGTRGRiGNGLSAEVALFYIDYDNELGSCSAAG---------GDRS 519
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 721 -YLNAQSARITGINILGKIDWNGVW-DKLPegWYSTFAYNRVRVRDikkrADRTDIQSHLFDAIQPSRYVIGLGYDQpeG 798
Cdd:COG4772   520 tFTNAGETRHQGLELALDYDLLKGGgLGLP--LFAAYTYTDAEFTS----DFGPVFAGNRLPYVPRHQLTAGLGYEH--G 591
                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 799 KWGVNGMLTYSkakeitellgSRALlnGNSRNTKATARRTR-PWY-IVDVSGYYTIKKHFTLRAGVYNLLNHRYVTwenv 876
Cdd:COG4772   592 GWTANLNGRYV----------SEQF--TDAANTVADGSFGKiPSYtVLDLSASYDFGKNLSLFAGVNNLFDKRYIA---- 655
                         890       900       910
                  ....*....|....*....|....*....|....*
gi 2559317374 877 rqtaGGAVNqhknvGVYNRYAAPGRNYTFSLEMRF 911
Cdd:COG4772   656 ----SRAPN-----YAAGIRPGPPRTVYAGLRLKF 681
FhuE COG4773
Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion ...
17-911 8.14e-20

Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion transport and metabolism];


Pssm-ID: 443805 [Multi-domain]  Cd Length: 692  Bit Score: 94.96  E-value: 8.14e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374  17 MTALPVYAENVQAGQAQEKQLDTIQVKAKKQKTR--RDNEVTGLGKL------------VKTADTLSKEQVLDIRDLTRY 82
Cdd:COG4773    12 AAAAGALAQAAAAAAAEATTLPEVTVTGTAEGTGgyTAKSSSTATKLdtplretpqsvsVVTRQLIEDQGATTLDDALRN 91
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374  83 DPGIAVVEQGRGASSGYSIRGMDKNRVslTVDGLAQIQSYTAQaalggtrtagssgaineIEYENVKAVEISKGSNSVEQ 162
Cdd:COG4773    92 VPGVTVSSYDGGGRDSFSIRGFSIDNY--LRDGLPLGGFGGGQ-----------------PDTANLERVEVLKGPAGLLY 152
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 163 GSGALAGSVAFQTKTA-DDVIGEGRQ----WGIQSKTA-YSGKnrgLTQSIALAGRIGGAeallihtgrrageiraheaa 236
Cdd:COG4773   153 GAGSPGGLVNLVTKRPtAEPQGEVSLsagsWDTYRATAdVGGP---LNEDGTLRYRLNAA-------------------- 209
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 237 grgvqsfnrlvpVEDTNQYanfiveeecesrnyetckanpkkdvvgkderqtvstRDYTGPNRFLADPlsyeSRSWLFRP 316
Cdd:COG4773   210 ------------YEDGDSF------------------------------------RDGVDNRRTLIAP----SLDWDLTD 237
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 317 GFRFEnkrhyIGGILERTQQTFDTRdmTVPAFLTKEVFDANKNplpgygkyagdhkYGGLFTKVENDAevgaeygTGVFY 396
Cdd:COG4773   238 DTTLT-----LGAEYQDDDSTGDRG--FLPLDGTLLDLPRSTN-------------LGEPWDYYDTET-------TTLFA 290
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 397 DETHTKSrygleyvytnadkDTWAdyARLSYDRQDIGLDNHFQQTHCSADGSDKYCRPSADKPSSYYKSDrviygeshkL 476
Cdd:COG4773   291 ELEHRFN-------------DDWS--LRANARYSDSDRDGRSAYAYGAPDAATGTLTRYASARDGDSRSD---------S 346
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 477 LQAAFKKSFDTAKIRHNLSVnlGFDRFGSNLRHQDYYSQSADraylpktthPDNPkisLNGSQDKPYWVSIGggnvkkke 556
Cdd:COG4773   347 LDANLNGKFETGGLEHTLLV--GADYSRYDSDSDSATAGTIN---------IYNP---VYGNLPEPDFDASD-------- 404
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 557 lclsssnnyadcTPRSINGKSYYAAvrDNVRLGRWADVGAGLRYDYRSTHSDDGSVSTGTHRT---LSWNVGIVLKPANW 633
Cdd:COG4773   405 ------------TDTTTRQTGLYAQ--DQISLTDRLSLLLGGRYDWYETDSTNRLGGSTTSYDdsaFTPRAGLVYDLTPG 470
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 634 LDL--TYraSTGFRLPSFAEMYGwrsgdkikaVKIDPEKSFNKEAGIvfKGDF----GNLEASWF-----NNAYRDLIVR 702
Cdd:COG4773   471 LSLyaSY--SESFEPQSGADNNG---------NPLDPETGKQYEAGV--KGELfdgrLNATLAVFditqkNVATTDPDNP 537
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 703 GYEAQIknGKEEAKGdpaylnaqsaritginilgkIDWNGVWdKLPEGW--YSTFAYNRVRVRDikkraDRTDIQSHLFD 780
Cdd:COG4773   538 NFYVQV--GEVRSRG--------------------VELELSG-ELTPGLnlIAGYTYTDAKITK-----DADALEGKRLT 589
                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 781 AIqpSRYVIGLG--YDQPEG---KWGVNGMLTYSkakeitellGSRALLNGNSRNTKATARrtrpwyiVDVSGYYTIKKH 855
Cdd:COG4773   590 NV--PRHTASLWttYRFPSGalkGLGLGGGVRYV---------GERYGDAANTFTLPSYTL-------VDAGARYDLGKN 651
                         890       900       910       920       930
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2559317374 856 FTLRAGVYNLLNHRYVTwenvrqTAGGAvnqhknvgVYNRYAAPgRNYTFSLEMRF 911
Cdd:COG4773   652 WTLQLNVNNLFDKKYYA------SSGSR--------GYVYYGAP-RNVRLSLSYKF 692
Plug pfam07715
TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently ...
62-169 4.28e-19

TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently folding subunit of the TonB-dependent receptors. It acts as the channel gate, blocking the pore until the channel is bound by ligand. At this point it under goes conformational changes opens the channel.


Pssm-ID: 462243 [Multi-domain]  Cd Length: 107  Bit Score: 83.47  E-value: 4.28e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374  62 VKTADTLSKEQVLDIRDLTRYDPGIAVVEQGRGASSGYSIRGMDKNRVSLTVDGLAQIQSYtaqaalggtrtaGSSGAIN 141
Cdd:pfam07715  11 VVTAEDIEDQGATNLADALRGVPGVSVSSGGGGGGSSISIRGFGSNRVLVLVDGVPLNSGG------------GGSVDLN 78
                          90       100
                  ....*....|....*....|....*...
gi 2559317374 142 EIEYENVKAVEISKGSNSVEQGSGALAG 169
Cdd:pfam07715  79 SIDPEDIERVEVLKGPASALYGSGAIGG 106
TonB-siderophor TIGR01783
TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of ...
62-911 5.38e-13

TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of TonB-dependent outer membrane siderophore receptors. It has no overlap with TonB receptors known to transport other substances, but is likely incomplete due to lack of characterizations. It is likely that genuine siderophore receptors will be identified which score below the noise cutoff to this model at which point the model should be updated. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273805 [Multi-domain]  Cd Length: 651  Bit Score: 72.83  E-value: 5.38e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374  62 VKTADTLSKEQVLDIRDLTRYDPGIAVVE-QGRGASSGYSIRGMDKNRVSLTV--DGLAQIqsytaqaalggtrtagSSG 138
Cdd:TIGR01783   8 VITRQELEDQQAGSLSEALQRVPGVVVGGsGGTTQFGNITIRGFGLEVDIDNVylDGVPLL----------------SRG 71
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 139 AINEIEYENVKAVEISKGSNSVEQGSGALAGSVAFQTKTADD--VIGEGRQWGIQSKTAYSGKNRG-LTQSIALAGRIGG 215
Cdd:TIGR01783  72 NLAIVDPAMVERVEVLRGPASLLYGGSAPGGVINIVTKRPQDepKGSVTFGAGTRSGYRTAFDLGGpLGADGTFRGRLNG 151
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 216 AeallihtGRRAGEIRAHEAAGRGVQSfnrlvpvedtnqyanfiveeecesrnyetckanpkkdvvgkdeRQTVSTRDyt 295
Cdd:TIGR01783 152 A-------RQDGDSFYDGAGEETRLGA-------------------------------------------TATDWQLD-- 179
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 296 gpnrfladplsyesrswlfrpgfrfenkrhyiggilERTQQTFDTRdmtvpafltkevfdanknplpgYGKYAGDHKYGG 375
Cdd:TIGR01783 180 ------------------------------------DRTLLRLGAY----------------------YQKERDRGGYGG 201
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 376 L-------FTKVENDAEVGAEYGTGVfYDETHTKSRYGLEYVYtnadKDTWADYARLSYDRQDIgLDNHFQQTHCSADGs 448
Cdd:TIGR01783 202 LpasggtsGRDLSSDRYLGTSSNRNY-DDREYLSYGLSLEYQF----NDVWTGKQNLRYSYFDT-DSNQVQASGYSSDG- 274
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 449 dKYCRPSAdkPSSYYKSDRVIygeshklLQAAFKKSFDTAKIRHNLSVNLG-FDRFGSNLRHQDYYSQsadraylpktth 527
Cdd:TIGR01783 275 -GLFGRSL--TVVNVKQDRVQ-------IDAGLDGEFETGPIEHDLLLGVSyGQRTTNRFNNTGYPSD------------ 332
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 528 pdnpkislngsqDKPYWVSIGGGNvkkkelclsSSNNYADCTPRSINGKSYYAAVRDNVRL--GRWaDVGAGLRYD---Y 602
Cdd:TIGR01783 333 ------------NIYSLTATSSAR---------TDIGDSPKDRALSSTTKALNGVALQRILlaDKW-TLTLGGRYDsvdV 390
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 603 RSTHSDDGSVSTGTHRTLSWNVGIVLKPANWLDLTYRASTGFRLPSFAEMYGWRSGDKIKavkidPEKSFNKEAGivFKG 682
Cdd:TIGR01783 391 KSNNGVAGSTGKRDDSQFTPSLGVAYKPTDDWSLYASYAESFKPGGYYPKGAGNSGDILE-----PEKGKNYELG--VRY 463
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 683 DFGNL---EASWFNNAYRDLIVrgyeaqikngkEEAKGDPAYLNAQSARITGinilgkIDWNGVWDKLP-EGWYSTFAYN 758
Cdd:TIGR01783 464 DLGDSllaTAALFRITKDNQLV-----------QDPVNGTFSVNAGKTRNRG------VELEARGYLTPgLSLSAGYTYT 526
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 759 RVRVRdikkraDRTDIQSHLFDAIQPSRYVIGLG--YDQPEGKWGVNgmltyskakeitelLGSRALLNGNSRNTKATAR 836
Cdd:TIGR01783 527 DAEFT------EDTNGDTQGNTVPFVPKHTASLWasYAPPVGDNGLT--------------LGGGVQYTGKAYVDGGNTG 586
                         810       820       830       840       850       860       870
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2559317374 837 RTRPWYIVDVSGYY--TIKKHFTLRAGVYNLLNHRYvtWENVRQTAGGAVNqhknvgvynrYAAPGRNYTFSLEMRF 911
Cdd:TIGR01783 587 KVPSYTVVDLSVRYdlTKKKNLTLALNVNNLFDRDY--YTSGYRWGPSAYI----------YPGAPRTVGLSVSYDF 651
PRK13524 PRK13524
FepA family TonB-dependent siderophore receptor;
570-911 8.94e-11

FepA family TonB-dependent siderophore receptor;


Pssm-ID: 237410 [Multi-domain]  Cd Length: 744  Bit Score: 65.82  E-value: 8.94e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 570 PRSiNGKSYYAAVRDNVRLGRWADVGAGLRYDYRSTHSDDGSVSTGTHRTLSWNV----GI--VLKPANwldlTYRASTG 643
Cdd:PRK13524  426 PYS-KAEIFSLFAEDNMELTDSTMLTPGLRFDHHSIVGNNWSPSLNLSQGLGDDFtlkmGIarAYKAPN----LYQTNPN 500
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 644 FRLPSFAE-MYGWRSG-------DKIKAvkidpEKSFNKEAGIVFKGDFGNLEASWFNNAYRDLIVRGYE--AQIKNGKE 713
Cdd:PRK13524  501 YILYSKGQgCYASAGNgcylqgnDDLKA-----ETSVNKEIGLEFKRDGWLAGLTWFRNDYRNKIEAGYVpvGTNSVGKT 575
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 714 EAKgdpAYLNAQSARITGINILGKIDWNGVWDklpegWYSTFAYNrVRVRDiKKRADRTdiqshlfdAIQPsRYVIGLGY 793
Cdd:PRK13524  576 DIY---QWENVPKAVVEGLEGTLNVPVSETVN-----WTNNLTYM-LQSKN-KTTGDPL--------SIIP-EYTLNSTL 636
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 794 D-QPEGKWGVNGMLTY---SKAKEitellgsralLNGNSRNTKATARRTR-PWYIVDVSGYYTIKKHFTLRAGVYNLLNH 868
Cdd:PRK13524  637 SwQATEDLSLQSTFTWygkQKPKK----------YNYKGQPVTGSATKEVsPYSIVGLSATYDVTKNVSLTGGVDNLFDK 706
                         330       340       350       360
                  ....*....|....*....|....*....|....*....|...
gi 2559317374 869 RYVTWENVRQTaggaVNQHKNVGVYNrYAAPGRNYTFSLEMRF 911
Cdd:PRK13524  707 RLWREGNAQTT----GDLIAGAGAYT-YNEPGRTYYMSLNTHF 744
BtuB COG4206
Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism];
55-245 4.99e-10

Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism];


Pssm-ID: 443355 [Multi-domain]  Cd Length: 276  Bit Score: 61.43  E-value: 4.99e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374  55 VTGLGKLVKTADTLSKEQVLDIRDLT-----------RYDPGIAVVEQGR-GASSGYSIRGMDKNRVSLTVDGlaqIQSY 122
Cdd:COG4206     3 VTATRLEQSKSDLTGSVTVIDAEELErsgatsladalRRVPGVQVSSSGGpGSAASISIRGLGSNQTLVLIDG---VPLN 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 123 TAQaalggtrtaGSSGAINEIEYENVKAVEISKGSNSVEQGSGALAGSVAFQTKTADDvigeGRQWGIQSKTAYSGKNRG 202
Cdd:COG4206    80 DPS---------LGGVDLSLIPPDDIERIEVLKGAASALYGSDAIGGVINITTKKGKK----GFKGSVSASYGSFGTRRL 146
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 2559317374 203 ltqSIALAGRIGGAEALLIHTGRRAGEIRAHEAAGRGVQSFNR 245
Cdd:COG4206   147 ---SASLSGGAGKFSYSLSASYRRSDGYRYNDPDLRNNDGYEN 186
PRK13528 PRK13528
outer membrane receptor FepA; Provisional
582-911 7.67e-09

outer membrane receptor FepA; Provisional


Pssm-ID: 237413 [Multi-domain]  Cd Length: 727  Bit Score: 59.38  E-value: 7.67e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 582 VRDNVRLGRWADVGAGLRYDYRSTHSDDGSVSTGTHRTLSWNV----GI--VLKPANwldlTYRASTGFRLPS------F 649
Cdd:PRK13528  429 VEDNIEPVPGTNLIPGLRFDYHSEFGSNWSPSLNLSQELGDYFkvkaGIarAFKAPN----LYQSSEGYLLYSrgngcpK 504
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 650 AEMYG--WRSGDKikavKIDPEKSFNKEAGIVFKGDFGNLEASWFNNAYRDLIVRGYeaqikngkeeakgDPAYLNAQSA 727
Cdd:PRK13528  505 DITSGgcYLVGNK----NLDPEISVNKEIGLEFTVDDYHASVTYFRNDYQNKIVAGD-------------DVIGRTASGA 567
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 728 RItginilgkIDWNGVWDKLPEGWYSTFAynrvrvrdIKKRADRTD--------IQSHLFDAIQP----SRYVIGLGYD- 794
Cdd:PRK13528  568 YI--------LQWQNGGKAVVEGLEGNLL--------VPLMKDRLNwntnatymITSEQKDTGNPlsviPKYTINSTLDw 631
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 795 QPEGKWGVNGMLT-YSKAKeitellgSRALLNGNSRNTKATARRTR-PWYIVDVSGYYTIKKHFTLRAGVYNLLNHRYvt 872
Cdd:PRK13528  632 QITQALSANVNWTlYGKQK-------PRTHAESRSEETGGLSGKELgAYSLVGVNVNYDINKNLRLNVGVSNLFDKQI-- 702
                         330       340       350
                  ....*....|....*....|....*....|....*....
gi 2559317374 873 wenVRQTAGGAvnqhknvgVYNRyaaPGRNYTFSLEMRF 911
Cdd:PRK13528  703 ---YREGEGAN--------TYNE---PGRAYYAGVTASF 727
PRK13483 PRK13483
ligand-gated channel protein;
549-867 6.05e-06

ligand-gated channel protein;


Pssm-ID: 184080 [Multi-domain]  Cd Length: 660  Bit Score: 50.16  E-value: 6.05e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 549 GGNVKKKELCLSSSNNYADCTprSINGKSYYAAVRDNVRLGRWADVGAGLRYDyrsthsDDGSVstGTHrtLSWNVGIVL 628
Cdd:PRK13483  345 GAAYNHQDLTDETSNQISDLT--DISRTQWAVFSEDEWRIADDFALTGGLRLD------HDENF--GGH--VSPRVYGVW 412
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 629 KPANWLDLTYRASTGFRLPSFAEMY-GW----RSGDKIKAVKIDPEKSFNKEAGIVFKGDFG-NLEASWFNNAYRDLIVR 702
Cdd:PRK13483  413 NLAPSWTVKGGVSTGFRAPSLRQTTpDWgqvsRGGNIYGNPDLKPETSLNKELGLYYDLGSGlTASLTVFYNEFKDKITR 492
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 703 GY--EAQIKNGKEEAKGDPA-YLNAQSARITGINIlgKIDWngvwdKLPEGWYSTFAYNRVRVRDIK---KRADRTDIQS 776
Cdd:PRK13483  493 VAcpATQCTDGPNQFGADPTtYVNIDEAVTQGVEA--SLSY-----PITSTLSLSGNYTYTDSEQKSgayKGSPLNQLPK 565
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374 777 HLFDAiqpsryviGLGYdQPEGKWGVNGMLTYsKAKEitellgsRALLNGNSRNTkatarRTRPWY-IVDVSGYYTIKKH 855
Cdd:PRK13483  566 HLFQA--------SLNW-EPTDRLNSWARVNY-RGEE-------SQPTTGPSSSS-----FIAPSYtFLDLGANYQLTDN 623
                         330
                  ....*....|..
gi 2559317374 856 FTLRAGVYNLLN 867
Cdd:PRK13483  624 LKLSAGIYNLFD 635
PRK10064 PRK10064
catecholate siderophore receptor CirA; Provisional
6-189 1.49e-05

catecholate siderophore receptor CirA; Provisional


Pssm-ID: 236646 [Multi-domain]  Cd Length: 663  Bit Score: 48.73  E-value: 1.49e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374   6 LFRLNI-----LCLSLMT-ALPVYAEnvqagqaqEKQLDTIQVKAKkqkTRRDNEVTGLGKL-VKTADTLSKEQVLDIRD 78
Cdd:PRK10064    1 MFRLNPfvrvgLCASAIScAWPVLAV--------DDDGETMVVTAS---AVEQNLKDAPASIsVITQEDLQRKPVQNLKD 69
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374  79 LTRYDPGIAVVEQGRGaSSGYSIRGMDKNRVSLTVDGlAQIQSYTAQaalggtrTAGSSGAINEIEYENVKAVEISKGSN 158
Cdd:PRK10064   70 VLKEVPGVQLTNEGDN-RKGVSIRGLDSSYTLILIDG-KRVNSRNAV-------FRHNDFDLNWIPVDAIERIEVVRGPM 140
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 2559317374 159 SVEQGSGALAGSVAFQTK----------TADDVIGEGRQWG 189
Cdd:PRK10064  141 SSLYGSDALGGVVNIITKkigqkwhgtvTVDTTIQEHRDRG 181
btuB PRK10641
TonB-dependent vitamin B12 receptor BtuB;
15-180 4.54e-03

TonB-dependent vitamin B12 receptor BtuB;


Pssm-ID: 236730 [Multi-domain]  Cd Length: 614  Bit Score: 40.75  E-value: 4.54e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374  15 SLMTALPVYAenvQAGQAQEKQLDTIQVKAK--KQKTrrdNEVTGLGKLVkTADTLSKEQVLDIRDLTRYDPGIAVVEQG 92
Cdd:PRK10641    6 SLLTALSVTA---FSGWAQDTSPDTLVVTANrfQQPV---STVLAPTTVV-TRDDIDRWQSKSVNDVLRRLPGVDIAQNG 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2559317374  93 -RGASSGYSIRGMDKNRVSLTVDG--LAQiqsytaqaalggtrtAGSSGA--INEIEYENVKAVEISKGSNSVEQGSGAL 167
Cdd:PRK10641   79 gLGQLSSLFIRGTNSSHVLVLIDGvrLNQ---------------AGISGSadLSQIPISLVQRIEYIRGPRSAVYGSDAI 143
                         170
                  ....*....|...
gi 2559317374 168 AGSVAFQTKTADD 180
Cdd:PRK10641  144 GGVVNIITTRDKP 156
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH