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Conserved domains on  [gi|2561759346|ref|WP_305367051|]
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MULTISPECIES: transketolase C-terminal domain-containing protein, partial [unclassified Staphylococcus]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
TktA super family cl33744
Transketolase [Carbohydrate transport and metabolism]; Transketolase is part of the Pathway ...
2-137 1.09e-72

Transketolase [Carbohydrate transport and metabolism]; Transketolase is part of the Pathway/BioSystem: Pentose phosphate pathway


The actual alignment was detected with superfamily member COG0021:

Pssm-ID: 439792 [Multi-domain]  Cd Length: 661  Bit Score: 228.74  E-value: 1.09e-72
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2561759346   2 LDVDEETVEqGVRKGAYVVFETETKPEYLLLATGSEVSLAIEAAKDLDKQGKGVRVVSMPNWFAFEQQSEEYKESVIPKE 81
Cdd:COG0021   524 LDRTAAAAE-GVAKGAYVLADAEGTPDVILIATGSEVSLAVEAAELLAAEGIKVRVVSMPSWELFEAQDAAYRESVLPPA 602
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2561759346  82 ITKRVAIEMASPLGWHKYVGTEGKVIGIDQFGASAPGDLVVEKYGFTKENVLNQIR 137
Cdd:COG0021   603 VRARVAVEAGVTDGWYKYVGLDGAVIGIDTFGASAPAKVLFEEFGFTVENVVAAAK 658
 
Name Accession Description Interval E-value
TktA COG0021
Transketolase [Carbohydrate transport and metabolism]; Transketolase is part of the Pathway ...
2-137 1.09e-72

Transketolase [Carbohydrate transport and metabolism]; Transketolase is part of the Pathway/BioSystem: Pentose phosphate pathway


Pssm-ID: 439792 [Multi-domain]  Cd Length: 661  Bit Score: 228.74  E-value: 1.09e-72
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2561759346   2 LDVDEETVEqGVRKGAYVVFETETKPEYLLLATGSEVSLAIEAAKDLDKQGKGVRVVSMPNWFAFEQQSEEYKESVIPKE 81
Cdd:COG0021   524 LDRTAAAAE-GVAKGAYVLADAEGTPDVILIATGSEVSLAVEAAELLAAEGIKVRVVSMPSWELFEAQDAAYRESVLPPA 602
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2561759346  82 ITKRVAIEMASPLGWHKYVGTEGKVIGIDQFGASAPGDLVVEKYGFTKENVLNQIR 137
Cdd:COG0021   603 VRARVAVEAGVTDGWYKYVGLDGAVIGIDTFGASAPAKVLFEEFGFTVENVVAAAK 658
PLN02790 PLN02790
transketolase
12-139 1.30e-57

transketolase


Pssm-ID: 215424 [Multi-domain]  Cd Length: 654  Bit Score: 189.08  E-value: 1.30e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2561759346  12 GVRKGAYVVFETET--KPEYLLLATGSEVSLAIEAAKDLDKQGKGVRVVSMPNWFAFEQQSEEYKESVIPKEITKRVAIE 89
Cdd:PLN02790  524 GVEKGGYVISDNSSgnKPDLILIGTGSELEIAAKAAKELRKEGKKVRVVSMVCWELFEEQSDEYKESVLPSSVTARVSVE 603
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 2561759346  90 MASPLGWHKYVGTEGKVIGIDQFGASAPGDLVVEKYGFTKENVLNQIRTF 139
Cdd:PLN02790  604 AGSTFGWEKYVGSKGKVIGVDRFGASAPAGILYKEFGFTVENVVAAAKSL 653
Transketolase_C pfam02780
Transketolase, C-terminal domain; The C-terminal domain of transketolase has been proposed as ...
27-132 1.70e-11

Transketolase, C-terminal domain; The C-terminal domain of transketolase has been proposed as a regulatory molecule binding site.


Pssm-ID: 460693 [Multi-domain]  Cd Length: 124  Bit Score: 57.22  E-value: 1.70e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2561759346  27 PEYLLLATGSEVSLAIEAAKDLDKQGKGVRVVSMP-----NWFAFEQQSEEYKESVIPKEITKRVAI--EMASPLGWHKY 99
Cdd:pfam02780  10 DDVTIVAYGSMVEEALEAAELLAKEGISAEVVDLRtikplDKETILESVKKTGRLVTVEEAVPRGGFgsEVAAALAEEAF 89
                          90       100       110
                  ....*....|....*....|....*....|....*
gi 2561759346 100 VGTEGKV--IGIDQFGASAPGDLVVEKYGFTKENV 132
Cdd:pfam02780  90 DGLDAPVlrVGGPDFPEPGSADELEKLYGLTPEKI 124
 
Name Accession Description Interval E-value
TktA COG0021
Transketolase [Carbohydrate transport and metabolism]; Transketolase is part of the Pathway ...
2-137 1.09e-72

Transketolase [Carbohydrate transport and metabolism]; Transketolase is part of the Pathway/BioSystem: Pentose phosphate pathway


Pssm-ID: 439792 [Multi-domain]  Cd Length: 661  Bit Score: 228.74  E-value: 1.09e-72
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2561759346   2 LDVDEETVEqGVRKGAYVVFETETKPEYLLLATGSEVSLAIEAAKDLDKQGKGVRVVSMPNWFAFEQQSEEYKESVIPKE 81
Cdd:COG0021   524 LDRTAAAAE-GVAKGAYVLADAEGTPDVILIATGSEVSLAVEAAELLAAEGIKVRVVSMPSWELFEAQDAAYRESVLPPA 602
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2561759346  82 ITKRVAIEMASPLGWHKYVGTEGKVIGIDQFGASAPGDLVVEKYGFTKENVLNQIR 137
Cdd:COG0021   603 VRARVAVEAGVTDGWYKYVGLDGAVIGIDTFGASAPAKVLFEEFGFTVENVVAAAK 658
PLN02790 PLN02790
transketolase
12-139 1.30e-57

transketolase


Pssm-ID: 215424 [Multi-domain]  Cd Length: 654  Bit Score: 189.08  E-value: 1.30e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2561759346  12 GVRKGAYVVFETET--KPEYLLLATGSEVSLAIEAAKDLDKQGKGVRVVSMPNWFAFEQQSEEYKESVIPKEITKRVAIE 89
Cdd:PLN02790  524 GVEKGGYVISDNSSgnKPDLILIGTGSELEIAAKAAKELRKEGKKVRVVSMVCWELFEEQSDEYKESVLPSSVTARVSVE 603
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 2561759346  90 MASPLGWHKYVGTEGKVIGIDQFGASAPGDLVVEKYGFTKENVLNQIRTF 139
Cdd:PLN02790  604 AGSTFGWEKYVGSKGKVIGVDRFGASAPAGILYKEFGFTVENVVAAAKSL 653
PRK05899 PRK05899
transketolase; Reviewed
4-137 1.54e-56

transketolase; Reviewed


Pssm-ID: 235639 [Multi-domain]  Cd Length: 586  Bit Score: 184.95  E-value: 1.54e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2561759346   4 VDEETVEQGVRKGAYVVFETetkPEYLLLATGSEVSLAIEAAKDLDKQGKGVRVVSMPNWFAFEQQSEEYKESVIPKEIT 83
Cdd:PRK05899  453 LERTAQEEGVAKGGYVLRDD---PDVILIATGSEVHLALEAADELEAEGIKVRVVSMPSTELFDEQDAAYKESVLPAAVT 529
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2561759346  84 KRVAIEMASPLGWHKYVGTEGKVIGIDQFGASAPGDLVVEKYGFTKENVLNQIR 137
Cdd:PRK05899  530 ARVAVEAGVADGWYKYVGLDGKVLGIDTFGASAPADELFKEFGFTVENIVAAAK 583
PTZ00089 PTZ00089
transketolase; Provisional
11-139 1.90e-43

transketolase; Provisional


Pssm-ID: 173383 [Multi-domain]  Cd Length: 661  Bit Score: 150.60  E-value: 1.90e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2561759346  11 QGVRKGAYVVFETETKPEYLLLATGSEVSLAIEAAKDLDKQGKgVRVVSMPNWFAFEQQSEEYKESVIPKEITKRVAIEM 90
Cdd:PTZ00089  533 EGVLKGAYIVVDFTNSPQLILVASGSEVSLCVEAAKALSKELN-VRVVSMPCWELFDQQSEEYQQSVLPSGGVPVLSVEA 611
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 2561759346  91 ASPLGWHKYVgteGKVIGIDQFGASAPGDLVVEKYGFTKENVLNQIRTF 139
Cdd:PTZ00089  612 YVSFGWEKYS---HVHVGISGFGASAPANALYKHFGFTVENVVEKARAL 657
Transketolase_C pfam02780
Transketolase, C-terminal domain; The C-terminal domain of transketolase has been proposed as ...
27-132 1.70e-11

Transketolase, C-terminal domain; The C-terminal domain of transketolase has been proposed as a regulatory molecule binding site.


Pssm-ID: 460693 [Multi-domain]  Cd Length: 124  Bit Score: 57.22  E-value: 1.70e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2561759346  27 PEYLLLATGSEVSLAIEAAKDLDKQGKGVRVVSMP-----NWFAFEQQSEEYKESVIPKEITKRVAI--EMASPLGWHKY 99
Cdd:pfam02780  10 DDVTIVAYGSMVEEALEAAELLAKEGISAEVVDLRtikplDKETILESVKKTGRLVTVEEAVPRGGFgsEVAAALAEEAF 89
                          90       100       110
                  ....*....|....*....|....*....|....*
gi 2561759346 100 VGTEGKV--IGIDQFGASAPGDLVVEKYGFTKENV 132
Cdd:pfam02780  90 DGLDAPVlrVGGPDFPEPGSADELEKLYGLTPEKI 124
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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