|
Name |
Accession |
Description |
Interval |
E-value |
| IolD |
COG3962 |
TPP-dependent trihydroxycyclohexane-1,2-dione (THcHDO) dehydratase, myo-inositol metabolism ... |
1-608 |
0e+00 |
|
TPP-dependent trihydroxycyclohexane-1,2-dione (THcHDO) dehydratase, myo-inositol metabolism [Carbohydrate transport and metabolism];
Pssm-ID: 443162 [Multi-domain] Cd Length: 622 Bit Score: 1035.85 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 1 MTTIRLTAAQAMVKYLAAQMTP---EGVPYIAGCWAIFGHGNVAGLGEALYHQRDALPTYRGHNEQTMAHTAIAYSKQLR 77
Cdd:COG3962 2 MKTIRLTVAQALVRFLANQYVErdgEEQPLFAGVFGIFGHGNVAGLGQALEQDPDELPTYQGRNEQGMAHAAIAYAKQKN 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 78 RDRAMMVTSSIGPGATNMVTACALAYVNRLPVLFVPGDVFAHRGPDPVLQQPENFADGTVTATDTFRPVSRYFDRITRPE 157
Cdd:COG3962 82 RRRIMACTSSIGPGATNMVTAAALATANRLPVLLLPGDTFATRQPDPVLQQLEHFHDPTISVNDAFRPVSRYWDRITRPE 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 158 QLLTALPRAMRTMTDPADCGPVTLAFCQDVQAEAYDWPEAFFAPRVWHRRAAPPDAGELARVAELLEGAETPVIVAGGGT 237
Cdd:COG3962 162 QLMSALPRAMRVLTDPAETGAVTLALPQDVQAEAYDYPESFFAKRVHRIRRPPPDPAELARAVELIRAAKRPLIIAGGGV 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 238 HYGHATETLKDFAEAHQIPVVETQAGKSALPWDHPLNLGPIGVTGAESANTICAAADVVIGVGTRFQDFTTGSWSLFANP 317
Cdd:COG3962 242 RYSEATEALRAFAEATGIPVAETQAGKGALPWDHPLNLGGIGVTGTLAANALAAEADLVIGVGTRLQDFTTGSKTLFANP 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 318 ARKLVSLNVQAYDAMKHGAEPLCCDAKAGLEALSAALGGK----TFTAPDAALKADWFAKVDPLTDAPEedaNALPTDMQ 393
Cdd:COG3962 322 DVRFVNINVARFDAYKHDALPVVADAREGLEALTEALAGWrypaAWTDEAAELKAEWDAEVDRLYAPTN---GGLPTQAQ 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 394 VVGAVQRSAGPDTVVMCAAGTMPGELHKLWKAGRPGCYHMEYGFSCMGYEIAGALGIWMADPARDIVCFTGDGTYMMANS 473
Cdd:COG3962 399 VIGAVNEAAGPDDIVVCAAGSLPGDLHKLWRTRDPGTYHVEYGYSCMGYEIAGGLGVKLAEPDREVYVMVGDGSYLMLNS 478
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 474 ELATACMMGAKFTLVITDNRGFGCINRLQMGTGGAEFNCLLDHTVHE------NPSQIDFVAHAASMGAKAVKAASIAEL 547
Cdd:COG3962 479 ELVTSVQEGKKIIVVLLDNHGFGCINRLQMSTGSQSFGTELRDRDTEtgrldgGLLPVDFAANAASLGAKAYRVTTIAEL 558
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2564844288 548 EEHLAKASDHDGVYAIVLDTDPYPSTPHGGTWWEVGVPEVSTRPEVNEARATYETKRKTQR 608
Cdd:COG3962 559 RAALERAKAADRTTVIVIKTDPKTMTPGGGSWWDVGVAEVSERESVRAARAEYEEARAKQR 619
|
|
| myo_inos_iolD |
TIGR04377 |
3,5/4-trihydroxycyclohexa-1,2-dione hydrolase; Members of this protein family, 3,5 ... |
5-608 |
0e+00 |
|
3,5/4-trihydroxycyclohexa-1,2-dione hydrolase; Members of this protein family, 3,5/4-trihydroxycyclohexa-1,2-dione hydrolase (iolD), represent one of eight enzymes in a pathway converting myo-inositol to acetyl-CoA. IolD hydrolyzes the cyclic molecule 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione to yield 5-deoxy-D-glucuronic acid. TPP is a cofactor. [Energy metabolism, Sugars]
Pssm-ID: 275170 [Multi-domain] Cd Length: 615 Bit Score: 1009.82 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 5 RLTAAQAMVKYLAAQMTP---EGVPYIAGCWAIFGHGNVAGLGEALYHQRDALPTYRGHNEQTMAHTAIAYSKQLRRDRA 81
Cdd:TIGR04377 1 RLTMAQALVRFLAAQYVErdgEEVPFFAGVFAIFGHGNVAGLGEALEEDPDDLPTYRGRNEQGMAHAAIAYAKQKNRRRI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 82 MMVTSSIGPGATNMVTACALAYVNRLPVLFVPGDVFAHRGPDPVLQQPENFADGTVTATDTFRPVSRYFDRITRPEQLLT 161
Cdd:TIGR04377 81 MACTSSIGPGATNMVTAAALATVNRLPVLLLPGDTFATRQPDPVLQQLEDFSDLTVSVNDAFRPVSRYFDRITRPEQLMT 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 162 ALPRAMRTMTDPADCGPVTLAFCQDVQAEAYDWPEAFFAPRVWHRRAAPPDAGELARVAELLEGAETPVIVAGGGTHYGH 241
Cdd:TIGR04377 161 ALPNAMRVLTDPAETGAVTLALPQDVQAEAYDYPESFFAKRVHRIRRPEPDPAELERAVAAIRAAKKPLIVAGGGVHYSE 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 242 ATETLKDFAEAHQIPVVETQAGKSALPWDHPLNLGPIGVTGAESANTICAAADVVIGVGTRFQDFTTGSWSLFANPARKL 321
Cdd:TIGR04377 241 AGEALAAFAEKHGIPVAETQAGKGALPWDHPLNLGAIGVTGTLAANALAAEADLVIAVGTRLQDFTTASKTLFQNPDVRF 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 322 VSLNVQAYDAMKHGAEPLCCDAKAGLEALSAALGG----KTFTAPDAALKADWFAKVDPLTdAPEEDANALPTDMQVVGA 397
Cdd:TIGR04377 321 VNINVARFDAYKHDALPLVADARAGLEALSEALGGyradSAWAAEAAAAKAAWDAEVDRLY-AAEYTAGGLPTQAEVIGA 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 398 VQRSAGPDTVVMCAAGTMPGELHKLWKAGRPGCYHMEYGFSCMGYEIAGALGIWMADPARDIVCFTGDGTYMMANSELAT 477
Cdd:TIGR04377 400 VNRAAGPDDVVVCAAGSLPGDLHKLWRTRDPGGYHMEYGYSCMGYEIAGGLGVKLAEPDREVYVMVGDGSYLMLNSELAT 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 478 ACMMGAKFTLVITDNRGFGCINRLQMGTGGAEFNCLL----DHTVHENPSQIDFVAHAASMGAKAVKAASIAELEEHLAK 553
Cdd:TIGR04377 480 SVQEGKKIIVVLLDNRGFGCINNLQMSTGGASFNTELryedTGRLDGGLLPVDFAAHAAALGAKTYKVTTIAELEAALAR 559
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....*
gi 2564844288 554 ASDHDGVYAIVLDTDPYPSTPHGGTWWEVGVPEVSTRPEVNEARATYETKRKTQR 608
Cdd:TIGR04377 560 AKAADRTTLIVIDTDPKTMTEGYGSWWDVGVAEVSERESVRKAREEYEEAKKAQR 614
|
|
| IlvB |
COG0028 |
Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme [Amino ... |
5-574 |
9.08e-107 |
|
Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme [Amino acid transport and metabolism, Coenzyme transport and metabolism]; Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis
Pssm-ID: 439799 [Multi-domain] Cd Length: 548 Bit Score: 332.51 E-value: 9.08e-107
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 5 RLTAAQAMVKYLAAqmtpEGVPYIAGcwaIFGhGNVAGLGEALYHQRDaLPTYRGHNEQTMAHTAIAYSKQLRRDRAMMV 84
Cdd:COG0028 2 KMTGADALVEALEA----EGVETVFG---VPG-GAILPLYDALRRQSG-IRHILVRHEQGAAFMADGYARATGKPGVCLV 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 85 TSsiGPGATNMVTACALAYVNRLPVLFVPGDV-FAHRGPDPvLQQpenfADgtvtATDTFRPVSRYFDRITRPEQLLTAL 163
Cdd:COG0028 73 TS--GPGATNLVTGLADAYMDSVPVLAITGQVpTSLIGRGA-FQE----VD----QVGLFRPITKWSYLVTDPEDLPEVL 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 164 PRAMRTMTDPAdCGPVTLAFCQDVQAEAYDWPEAFFAPRVWHRRAAPpDAGELARVAELLEGAETPVIVAGGGTHYGHAT 243
Cdd:COG0028 142 RRAFRIATSGR-PGPVVLDIPKDVQAAEAEEEPAPPELRGYRPRPAP-DPEAIEEAAELLAAAKRPVILAGGGARRAGAA 219
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 244 ETLKDFAEAHQIPVVETQAGKSALPWDHPLNLGPIGVTGAESANTICAAADVVIGVGTRFQDFTTGSWSLFAnPARKLVS 323
Cdd:COG0028 220 EELRALAERLGAPVVTTLMGKGAFPEDHPLYLGMLGMHGTPAANEALAEADLVLAVGARFDDRVTGNWDEFA-PDAKIIH 298
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 324 LNVQAY--DAMKHGAEPLCCDAKAGLEALSAALGGKTFTAPdaalkaDWFAKVDPLTDAPEEDANALPTDM---QVVGAV 398
Cdd:COG0028 299 IDIDPAeiGKNYPVDLPIVGDAKAVLAALLEALEPRADDRA------AWLARIAAWRAEYLAAYAADDGPIkpqRVIAAL 372
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 399 QRSAGPDTVVMCAAGTMPGELHKLWKAGRPGCYHMEYGFSCMGYEIAGALGIWMADPARDIVCFTGDGTYMMANSELATA 478
Cdd:COG0028 373 REALPDDAIVVTDVGQHQMWAARYLRFRRPRRFLTSGGLGTMGYGLPAAIGAKLARPDRPVVAITGDGGFQMNLQELATA 452
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 479 CMMGAKFTLVITDNRGFGCINRLQMGTGGAEFNclldHTVHENPsqiDFVAHAASMGAKAVKAASIAELEEHLAKASDHD 558
Cdd:COG0028 453 VRYGLPVKVVVLNNGGLGMVRQWQELFYGGRYS----GTDLPNP---DFAKLAEAFGAKGERVETPEELEAALEEALASD 525
|
570
....*....|....*.
gi 2564844288 559 GVYAIVLDTDPYPSTP 574
Cdd:COG0028 526 GPALIDVRVDPEENPP 541
|
|
| TPP_IolD |
cd02003 |
Thiamine pyrophosphate (TPP) family, IolD subfamily, TPP-binding module; composed of proteins ... |
393-589 |
4.79e-92 |
|
Thiamine pyrophosphate (TPP) family, IolD subfamily, TPP-binding module; composed of proteins similar to Rhizobium leguminosarum bv. viciae IolD. IolD plays an important role in myo-inositol catabolism.
Pssm-ID: 238961 [Multi-domain] Cd Length: 205 Bit Score: 282.27 E-value: 4.79e-92
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 393 QVVGAVQRSAGPDTVVMCAAGTMPGELHKLWKAGRPGCYHMEYGFSCMGYEIAGALGIWMADPARDIVCFTGDGTYMMAN 472
Cdd:cd02003 3 EVLGALNEAIGDDDVVINAAGSLPGDLHKLWRARTPGGYHLEYGYSCMGYEIAAGLGAKLAKPDREVYVLVGDGSYLMLH 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 473 SELATACMMGAKFTLVITDNRGFGCINRLQMGTGGAEFNCLLDHTVHENPSQ------IDFVAHAASMGAKAVKAASIAE 546
Cdd:cd02003 83 SEIVTAVQEGLKIIIVLFDNHGFGCINNLQESTGSGSFGTEFRDRDQESGQLdgallpVDFAANARSLGARVEKVKTIEE 162
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 2564844288 547 LEEHLAKASDHDGVYAIVLDTDPYPSTPHGGTWWEVGVPEVST 589
Cdd:cd02003 163 LKAALAKAKASDRTTVIVIKTDPKSMTPGYGSWWDVGVAEVSE 205
|
|
| PRK06276 |
PRK06276 |
acetolactate synthase large subunit; |
6-593 |
1.88e-50 |
|
acetolactate synthase large subunit;
Pssm-ID: 235766 [Multi-domain] Cd Length: 586 Bit Score: 183.80 E-value: 1.88e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 6 LTAAQAMVKYLAAqmtpEGVPyiagcwAIFGH--GNVAGLGEALYHQrDALPTYRGHnEQTMAHTAIAYSKQLRRDRAMM 83
Cdd:PRK06276 1 MKGAEAIIKALEA----EGVK------IIFGYpgGALLPFYDALYDS-DLIHILTRH-EQAAAHAADGYARASGKVGVCV 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 84 VTSsiGPGATNMVTACALAYVNRLPVLFVPGDVFAHRGPDPVLQQpenfadgtVTATDTFRPVSRYFDRITRPEQLltal 163
Cdd:PRK06276 69 ATS--GPGATNLVTGIATAYADSSPVIALTGQVPTKLIGNDAFQE--------IDALGIFMPITKHNFQIKKPEEI---- 134
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 164 PRAMRTMTDPADCG---PVTLAFCQDVQAEAYDWPEAFFAPRVWHRRAAPPDAG---ELARVAELLEGAETPVIVAGGGT 237
Cdd:PRK06276 135 PEIFRAAFEIAKTGrpgPVHIDLPKDVQEGELDLEKYPIPAKIDLPGYKPTTFGhplQIKKAAELIAEAERPVILAGGGV 214
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 238 HYGHATETLKDFAEAHQIPVVETQAGKSALPWDHPLNLGPIGVTGAESANTICAAADVVIGVGTRFQDFTTGSWSLFAnP 317
Cdd:PRK06276 215 IISGASEELIELSELVKIPVCTTLMGKGAFPEDHPLALGMVGMHGTKAANYSVTESDVLIAIGCRFSDRTTGDISSFA-P 293
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 318 ARKLVSLNVQAYDAMKH-GAE-PLCCDAKAGLEALSAALGGKtftapDAALKADWFAKVDPLTDA--PEEDANALPTDMQ 393
Cdd:PRK06276 294 NAKIIHIDIDPAEIGKNvRVDvPIVGDAKNVLRDLLAELMKK-----EIKNKSEWLERVKKLKKEsiPRMDFDDKPIKPQ 368
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 394 ----VVGAVQRSAGP--DTVVMCAAGTmpgelHKLWKA-----GRPGCYHMEYGFSCMGYEIAGALGIWMADPARDIVCF 462
Cdd:PRK06276 369 rvikELMEVLREIDPskNTIITTDVGQ-----NQMWMAhffktSAPRSFISSGGLGTMGFGFPAAIGAKVAKPDANVIAI 443
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 463 TGDGTYMMANSELATACMMGAKFTLVITDNRGFGCINRLQmgtggaefNCLLDH---TVH--ENPsqiDFVAHAASMGAK 537
Cdd:PRK06276 444 TGDGGFLMNSQELATIAEYDIPVVICIFDNRTLGMVYQWQ--------NLYYGKrqsEVHlgETP---DFVKLAESYGVK 512
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....*....
gi 2564844288 538 AVKAASIAELEEHLAKASDHDGVYAIVLDTDP---YPSTPHGGTWWEVgVPEVSTRPEV 593
Cdd:PRK06276 513 ADRVEKPDEIKEALKEAIKSGEPYLLDIIIDPaeaLPMVPPGGNLTNI-LGPYRVEPTV 570
|
|
| PRK08322 |
PRK08322 |
acetolactate synthase large subunit; |
6-568 |
5.33e-50 |
|
acetolactate synthase large subunit;
Pssm-ID: 236239 [Multi-domain] Cd Length: 547 Bit Score: 181.95 E-value: 5.33e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 6 LTAAQAMVKYLAAqmtpEGVPYIAGcwaIFGHGNVAGLgEALYHQRDALPTYRgHnEQTMAHTAIAYSkqlrR--DRAMM 83
Cdd:PRK08322 1 MKAADLFVKCLEN----EGVEYIFG---IPGEENLDLL-EALRDSSIKLILTR-H-EQGAAFMAATYG----RltGKAGV 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 84 VTSSIGPGATNMVTACALAYVNRLPVLFVPGDVFAHRgpdpvLQQpENFAdgTVTATDTFRPVSRYFDRITRPEQLLTAL 163
Cdd:PRK08322 67 CLSTLGPGATNLVTGVAYAQLGGMPMVAITGQKPIKR-----SKQ-GSFQ--IVDVVAMMAPLTKWTRQIVSPDNIPEVV 138
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 164 PRAMRTMTD--PadcGPVTLAFCQDVQAEAYDwpEAFFAPRVWHRRAAPPDAgeLARVAELLEGAETPVIVAGGGTHYGH 241
Cdd:PRK08322 139 REAFRLAEEerP---GAVHLELPEDIAAEETD--GKPLPRSYSRRPYASPKA--IERAAEAIQAAKNPLILIGAGANRKT 211
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 242 ATETLKDFAEAHQIPVVETQAGKSALPWDHPLNLGPIGVTGAESANTICAAADVVIGVGTRFQDFTTGSWslfaNPA--R 319
Cdd:PRK08322 212 ASKALTEFVDKTGIPFFTTQMGKGVIPETHPLSLGTAGLSQGDYVHCAIEHADLIINVGHDVIEKPPFFM----NPNgdK 287
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 320 KLVSLNVQAydamkhgAEP---------LCCDAKAGLEALSAALGGKTFTAPDAALkadwfakvdPLTDAPEEDANALPT 390
Cdd:PRK08322 288 KVIHINFLP-------AEVdpvyfpqveVVGDIANSLWQLKERLADQPHWDFPRFL---------KIREAIEAHLEEGAD 351
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 391 DMQ-------VVGAVQRSAGPDTVVMCAAGtmpgeLHKLWKAGRPGCYH-----MEYGFSCMGYEIAGALGIWMADPARD 458
Cdd:PRK08322 352 DDRfpmkpqrIVADLRKVMPDDDIVILDNG-----AYKIWFARNYRAYEpntclLDNALATMGAGLPSAIAAKLVHPDRK 426
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 459 IVCFTGDGTYMMANSELATACMMGAKFTLVITDNRGFGCINRLQMGTGGAEFNclLDHTvheNPsqiDFVAHAASMGAKA 538
Cdd:PRK08322 427 VLAVCGDGGFMMNSQELETAVRLGLPLVVLILNDNAYGMIRWKQENMGFEDFG--LDFG---NP---DFVKYAESYGAKG 498
|
570 580 590
....*....|....*....|....*....|
gi 2564844288 539 VKAASIAELEEHLAKASDHDGVYAIVLDTD 568
Cdd:PRK08322 499 YRVESADDLLPTLEEALAQPGVHVIDCPVD 528
|
|
| PRK06048 |
PRK06048 |
acetolactate synthase large subunit; |
2-582 |
3.81e-45 |
|
acetolactate synthase large subunit;
Pssm-ID: 180368 [Multi-domain] Cd Length: 561 Bit Score: 168.41 E-value: 3.81e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 2 TTIRLTAAQAMVKYLAAqmtpEGVPyiagcwAIFGHGnvaglGEALYHQRDALptYRGH-------NEQTMAHTAIAYSK 74
Cdd:PRK06048 4 STEKMTGARAIIKCLEK----EGVE------VIFGYP-----GGAIIPVYDEL--YDSDlrhilvrHEQAAAHAADGYAR 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 75 QLRRDRAMMVTSsiGPGATNMVTACALAYVNRLPVLFVPGDVfahrgPDPVLQQpENFADGTVTATDTfrPVSRYFDRIT 154
Cdd:PRK06048 67 ATGKVGVCVATS--GPGATNLVTGIATAYMDSVPIVALTGQV-----PRSMIGN-DAFQEADITGITM--PITKHNYLVQ 136
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 155 RPEQLLTALPRAMRtMTDPADCGPVTLAFCQDVQAEA--YDWPEaffapRVWHRRAAPPDAG---ELARVAELLEGAETP 229
Cdd:PRK06048 137 DAKDLPRIIKEAFH-IASTGRPGPVLIDLPKDVTTAEidFDYPD-----KVELRGYKPTYKGnpqQIKRAAELIMKAERP 210
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 230 VIVAGGGTHYGHATETLKDFAEAHQIPVVETQAGKSALPWDHPLNLGPIGVTGAESANTICAAADVVIGVGTRFQDFTTG 309
Cdd:PRK06048 211 IIYAGGGVISSNASEELVELAETIPAPVTTTLMGIGAIPTEHPLSLGMLGMHGTKYANYAIQESDLIIAVGARFDDRVTG 290
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 310 SWSLFAnPARKLVSLNVQAYDAMKHGAE--PLCCDAKAGLEALSAALGGKTFtapdaalkADWFAKVD------PLTDAP 381
Cdd:PRK06048 291 KLASFA-PNAKIIHIDIDPAEISKNVKVdvPIVGDAKQVLKSLIKYVQYCDR--------KEWLDKINqwkkeyPLKYKE 361
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 382 EEDAnALPtdmQVVGAVQRSAGPDTVVMCAAGTmpgelHKLW-----KAGRPGCYHMEYGFSCMGYEIAGALGIWMADPA 456
Cdd:PRK06048 362 REDV-IKP---QYVIEQIYELCPDAIIVTEVGQ-----HQMWaaqyfKYKYPRTFITSGGLGTMGYGFPAAIGAKVGKPD 432
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 457 RDIVCFTGDGTYMMANSELATACMMGAKFTLVITDNRGFGCINRLQMgtggAEFNCLLDHTVHENpsQIDFVAHAASMGA 536
Cdd:PRK06048 433 KTVIDIAGDGSFQMNSQELATAVQNDIPVIVAILNNGYLGMVRQWQE----LFYDKRYSHTCIKG--SVDFVKLAEAYGA 506
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|
gi 2564844288 537 KAVKAASIAELEEHL--AKASDHDGVYAIVLDTDP--YPSTPHGGTWWEV 582
Cdd:PRK06048 507 LGLRVEKPSEVRPAIeeAVASDRPVVIDFIVECEEnvSPMVPAGAAINEI 556
|
|
| PRK06456 |
PRK06456 |
acetolactate synthase large subunit; |
61-582 |
1.84e-44 |
|
acetolactate synthase large subunit;
Pssm-ID: 180569 [Multi-domain] Cd Length: 572 Bit Score: 166.94 E-value: 1.84e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 61 NEQTMAHTAIAYSKQLRRDRAMMVTSsiGPGATNMVTACALAYVNRLPVLFVPGDVfahrgPDPVLQQpenFADGTVTAT 140
Cdd:PRK06456 51 HEQAAAHAADGYARASGVPGVCTATS--GPGTTNLVTGLITAYWDSSPVIAITGQV-----PRSVMGK---MAFQEADAM 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 141 DTFRPVSRYFDRITRPEQLLTALPRAMRTMTDpADCGPVTLAFCQDVQAEAYD---WPEAffaPRVWHRRAAPP--DAGE 215
Cdd:PRK06456 121 GVFENVTKYVIGIKRIDEIPQWIKNAFYIATT-GRPGPVVIDIPRDIFYEKMEeikWPEK---PLVKGYRDFPTriDRLA 196
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 216 LARVAELLEGAETPVIVAGGGTHYGHATETLKDFAEAHQIPVVETQAGKSALPWDHPLNLGPIGVTGAESANTICAAADV 295
Cdd:PRK06456 197 LKKAAEILINAERPIILVGTGVVWSNATPEVLELAELLHIPIVSTFPGKTAIPHDHPLYFGPMGYYGRAEASMAALESDA 276
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 296 VIGVGTRFQDFTTGSWSLFANPARKLVSLNVQAYDAMK--HGAEPLCCDAKAGLEALSAALggktftaPDAALKAD---W 370
Cdd:PRK06456 277 MLVVGARFSDRTFTSYDEMVETRKKFIMVNIDPTDGEKaiKVDVGIYGNAKIILRELIKAI-------TELGQKRDrsaW 349
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 371 FAKVDPLTD------APEEDANALPtdMQVVGAVQRSAGPDTVVMCAAGTMPGELHKLWKAGRPGCYHMEYGFSCMGYEI 444
Cdd:PRK06456 350 LKRVKEYKEyysqfyYTEENGKLKP--WKIMKTIRQALPRDAIVTTGVGQHQMWAEVFWEVLEPRTFLTSSGMGTMGFGL 427
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 445 AGALGIWMADPARDIVCFTGDGTYMMANSELATACMMGAKFTLVITDNRGFGCINRLQ-MGTGGAEFNclldhtVHENPS 523
Cdd:PRK06456 428 PAAMGAKLARPDKVVVDLDGDGSFLMTGTNLATAVDEHIPVISVIFDNRTLGLVRQVQdLFFGKRIVG------VDYGPS 501
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2564844288 524 QiDFVAHAASMGAKAVKAASIAELEEHLAKASDHDGVYAIVLDTD----PYPSTPHGGTWWEV 582
Cdd:PRK06456 502 P-DFVKLAEAFGALGFNVTTYEDIEKSLKSAIKEDIPAVIRVPVDkeelALPTLPPGGRLKQV 563
|
|
| PRK07282 |
PRK07282 |
acetolactate synthase large subunit; |
34-502 |
1.63e-42 |
|
acetolactate synthase large subunit;
Pssm-ID: 180919 [Multi-domain] Cd Length: 566 Bit Score: 161.14 E-value: 1.63e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 34 IFGH--GNVAGLGEALYHQrDALPTYRGHNEQTMAHTAIAYSKQLRRDRAMMVTSsiGPGATNMVTACALAYVNRLPVLF 111
Cdd:PRK07282 28 IFGYpgGAVLPLYDAIYNF-EGIRHILARHEQGALHEAEGYAKSTGKLGVAVVTS--GPGATNAITGIADAMSDSVPLLV 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 112 VPGDVfahrGPDPVLQQPENFADgTVTATdtfRPVSRYFDRITRpeqllTA-LPRAMRTMTDPADC---GPVTLAFCQDV 187
Cdd:PRK07282 105 FTGQV----ARAGIGKDAFQEAD-IVGIT---MPITKYNYQIRE-----TAdIPRIITEAVHIATTgrpGPVVIDLPKDV 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 188 QAEAYDWpeaFFAPRVWHRRAAP---PDAGELARVAELLEGAETPVIVAGGGTHYGHATETLKDFAEAHQIPVVETQAGK 264
Cdd:PRK07282 172 SALETDF---IYDPEVNLPSYQPtlePNDMQIKKILKQLSKAKKPVILAGGGINYAEAATELNAFAERYQIPVVTTLLGQ 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 265 SALPWDHPLNLGPIGVTGAESANTICAAADVVIGVGTRFQDFTTGSWSLFANPArKLVSLNVQAYDAMK--HGAEPLCCD 342
Cdd:PRK07282 249 GTIATSHPLFLGMGGMHGSYAANIAMTEADFMINIGSRFDDRLTGNPKTFAKNA-KVAHIDIDPAEIGKiiKTDIPVVGD 327
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 343 AKAGLEALSAALGGKTFTapdaalkADWFAKVD------PLTDAPEEDANAlptdMQVVGAVQRSAGPDTVVMCAAGTmp 416
Cdd:PRK07282 328 AKKALQMLLAEPTVHNNT-------EKWIEKVTkdknrvRSYDKKERVVQP----QAVIERIGELTNGDAIVVTDVGQ-- 394
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 417 gelHKLWKAG-RPgcYHMEY------GFSCMGYEIAGALGIWMADPARDIVCFTGDGTYMMANSELATACMMGAKFTLVI 489
Cdd:PRK07282 395 ---HQMWAAQyYP--YQNERqlvtsgGLGTMGFGIPAAIGAKIANPDKEVILFVGDGGFQMTNQELAILNIYKVPIKVVM 469
|
490
....*....|...
gi 2564844288 490 TDNRGFGCINRLQ 502
Cdd:PRK07282 470 LNNHSLGMVRQWQ 482
|
|
| PRK08266 |
PRK08266 |
hypothetical protein; Provisional |
5-566 |
4.50e-42 |
|
hypothetical protein; Provisional
Pssm-ID: 181337 [Multi-domain] Cd Length: 542 Bit Score: 159.41 E-value: 4.50e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 5 RLTAAQAMVKYLAAqmtpEGVPYIAGcwaIFGhGNVAGLGEALYHQRDALPTYRGHNEQTMAHTAIAYSKQLRRDRAMMV 84
Cdd:PRK08266 3 TMTGGEAIVAGLVA----HGVDTVFG---LPG-AQLYWLFDALYKAGDRIRVIHTRHEQAAGYMAFGYARSTGRPGVCSV 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 85 TSsiGPGATNMVTACALAYVNRLPVLFVPGDVFAH---RGPDPVLQQPENFAdgtvtatdTFRPVSRYFDRITRPEQLLT 161
Cdd:PRK08266 75 VP--GPGVLNAGAALLTAYGCNSPVLCLTGQIPSAligKGRGHLHEMPDQLA--------TLRSFTKWAERIEHPSEAPA 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 162 ALPRAMRTMTDpADCGPVTLAFCQDV-QAEAydwpEAFFAPRVwhRRAAPP--DAGELARVAELLEGAETPVIVAGGGTH 238
Cdd:PRK08266 145 LVAEAFQQMLS-GRPRPVALEMPWDVfGQRA----PVAAAPPL--RPAPPPapDPDAIAAAAALIAAAKNPMIFVGGGAA 217
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 239 ygHATETLKDFAEAHQIPVVETQAGKSALPWDHPLNLGPIGvtgaesANTICAAADVVIGVGTRFQDFTTgSWSlFANPA 318
Cdd:PRK08266 218 --GAGEEIRELAEMLQAPVVAFRSGRGIVSDRHPLGLNFAA------AYELWPQTDVVIGIGSRLELPTF-RWP-WRPDG 287
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 319 RKLVSLNVqayDAMKHGAEP----LCCDAKAGLEALSAALGGKTFTAPD-----AALKADWFAKVDPLtdAPEED----- 384
Cdd:PRK08266 288 LKVIRIDI---DPTEMRRLKpdvaIVADAKAGTAALLDALSKAGSKRPSrraelRELKAAARQRIQAV--QPQASylrai 362
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 385 ANALPTDMQVV------GAVQRSA----GPDTVVMCA-AGTmpgelhklwkagrpgcyhmeygfscMGYEIAGALGIWMA 453
Cdd:PRK08266 363 REALPDDGIFVdelsqvGFASWFAfpvyAPRTFVTCGyQGT-------------------------LGYGFPTALGAKVA 417
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 454 DPARDIVCFTGDGTYMMANSELATACMMGAKFTLVITDNRGFGCINRLQMGT-GGAEFNCLLDhtvheNPsqiDFVAHAA 532
Cdd:PRK08266 418 NPDRPVVSITGDGGFMFGVQELATAVQHNIGVVTVVFNNNAYGNVRRDQKRRfGGRVVASDLV-----NP---DFVKLAE 489
|
570 580 590
....*....|....*....|....*....|....
gi 2564844288 533 SMGAKAVKAASIAELEEHLAKASDHDGVYAIVLD 566
Cdd:PRK08266 490 SFGVAAFRVDSPEELRAALEAALAHGGPVLIEVP 523
|
|
| PRK08155 |
PRK08155 |
acetolactate synthase large subunit; |
2-577 |
1.17e-41 |
|
acetolactate synthase large subunit;
Pssm-ID: 181257 [Multi-domain] Cd Length: 564 Bit Score: 158.72 E-value: 1.17e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 2 TTIRLTAAQAMVKYLAAQmtpeGVPYIAGcwaIFGhGNVAGLGEALyHQRDALPTYRGHNEQTMAHTAIAYSKQLRRDRA 81
Cdd:PRK08155 9 TRKRFTGAELIVRLLERQ----GIRIVTG---IPG-GAILPLYDAL-SQSTQIRHILARHEQGAGFIAQGMARTTGKPAV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 82 MMVTSsiGPGATNMVTACALAYVNRLPVLFVPGDVfahrgPDPVLqqpenfadgtvtATDTFRPVSRYfdRITRP----- 156
Cdd:PRK08155 80 CMACS--GPGATNLVTAIADARLDSIPLVCITGQV-----PASMI------------GTDAFQEVDTY--GISIPitkhn 138
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 157 ------EQLLTALPRAMRTMTD--PadcGPVTLAFCQDVQAEAYD---WPEAFfaprvwhRRAAPP--DAGELARVAELL 223
Cdd:PRK08155 139 ylvrdiEELPQVISDAFRIAQSgrP---GPVWIDIPKDVQTAVIEleaLPAPA-------EKDAAPafDEESIRDAAAMI 208
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 224 EGAETPVIVAGGGTHYGHATETLKDFAEAHQIPVVETQAGKSALPWDHPLNLGPIGVTGAESANTICAAADVVIGVGTRF 303
Cdd:PRK08155 209 NAAKRPVLYLGGGVINSGAPARARELAEKAQLPTTMTLMALGMLPKAHPLSLGMLGMHGARSTNYILQEADLLIVLGARF 288
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 304 QDFTTGSWSLFAnPARKLVSLNVQA--YDAMKHGAEPLCCDAKAGLEALSAALggktftapDAALKADWFAKVDPLT--- 378
Cdd:PRK08155 289 DDRAIGKTEQFC-PNAKIIHVDIDRaeLGKIKQPHVAIQADVDDVLAQLLPLV--------EAQPRAEWHQLVADLQref 359
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 379 --DAPEEDANALPTDMqvVGAVQRSAGPDTVVMCAAGTmpgelHKLWKA-----GRPGCYHMEYGFSCMGYEIAGALGIW 451
Cdd:PRK08155 360 pcPIPKADDPLSHYGL--INAVAACVDDNAIITTDVGQ-----HQMWTAqayplNRPRQWLTSGGLGTMGFGLPAAIGAA 432
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 452 MADPARDIVCFTGDGTYMMANSELATACMMGAKFTLVITDNRGFGCINRLQ-----MGTGGAEFnclldhtvhenPSQID 526
Cdd:PRK08155 433 LANPERKVLCFSGDGSLMMNIQEMATAAENQLDVKIILMNNEALGLVHQQQslfygQRVFAATY-----------PGKIN 501
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....*
gi 2564844288 527 FVAHAASMGAKAVKAASIAELEEHLAKASDHDGVYAIVLDTDP----YPSTPHGG 577
Cdd:PRK08155 502 FMQIAAGFGLETCDLNNEADPQAALQEAINRPGPALIHVRIDAeekvYPMVPPGA 556
|
|
| TPP_enzyme_M |
pfam00205 |
Thiamine pyrophosphate enzyme, central domain; The central domain of TPP enzymes contains a ... |
216-350 |
1.66e-41 |
|
Thiamine pyrophosphate enzyme, central domain; The central domain of TPP enzymes contains a 2-fold Rossman fold.
Pssm-ID: 425523 [Multi-domain] Cd Length: 137 Bit Score: 146.55 E-value: 1.66e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 216 LARVAELLEGAETPVIVAGGGTHYGHATETLKDFAEAHQIPVVETQAGKSALPWDHPLNLGPIGVTGAESANTICAAADV 295
Cdd:pfam00205 1 IEKAAELLKKAKRPVILAGGGVRRSGASEELRELAEKLGIPVVTTLMGKGAFPEDHPLYLGMLGMHGTPAANEALEEADL 80
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 2564844288 296 VIGVGTRFQDF-TTGSWSLFANPArKLVSLNVQAYDAMKH--GAEPLCCDAKAGLEAL 350
Cdd:pfam00205 81 VLAVGARFDDIrTTGKLPEFAPDA-KIIHIDIDPAEIGKNypVDVPIVGDAKETLEAL 137
|
|
| PRK07789 |
PRK07789 |
acetolactate synthase 1 catalytic subunit; Validated |
62-554 |
1.04e-40 |
|
acetolactate synthase 1 catalytic subunit; Validated
Pssm-ID: 236098 [Multi-domain] Cd Length: 612 Bit Score: 156.68 E-value: 1.04e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 62 EQTMAHTAIAYSKQLRRDRAMMVTSsiGPGATNMVTACALAYVNRLPVLFVPGDVFAHrgpdpvlqqpenfadgtVTATD 141
Cdd:PRK07789 78 EQGAGHAAEGYAQATGRVGVCMATS--GPGATNLVTPIADANMDSVPVVAITGQVGRG-----------------LIGTD 138
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 142 TFR---------PVSRYFDRITRPEQLltalPRAMRTMTDPADCG---PVTLAFCQDV-QAEA-YDWPEAFFAPRvwHRR 207
Cdd:PRK07789 139 AFQeadivgitmPITKHNFLVTDADDI----PRVIAEAFHIASTGrpgPVLVDIPKDAlQAQTtFSWPPRMDLPG--YRP 212
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 208 AAPPDAGELARVAELLEGAETPVIVAGGGTHYGHATETLKDFAEAHQIPVVETQAGKSALPWDHPLNLGPIGVTGAESAN 287
Cdd:PRK07789 213 VTKPHGKQIREAAKLIAAARRPVLYVGGGVIRAEASAELRELAELTGIPVVTTLMARGAFPDSHPQHLGMPGMHGTVAAV 292
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 288 TICAAADVVIGVGTRFQDFTTGSWSLFAnPARKLVSLNVQAYDAMK--HGAEPLCCDAKAGLEALSAALGGKTFTAPDAA 365
Cdd:PRK07789 293 AALQRSDLLIALGARFDDRVTGKLDSFA-PDAKVIHADIDPAEIGKnrHADVPIVGDVKEVIAELIAALRAEHAAGGKPD 371
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 366 LkADWFAKVD------PLTDAPEEDANALPTdmQVVGAVQRSAGPDTVVmcAAGTmpGElHKLWKA-----GRPGCYHME 434
Cdd:PRK07789 372 L-TAWWAYLDgwretyPLGYDEPSDGSLAPQ--YVIERLGEIAGPDAIY--VAGV--GQ-HQMWAAqfidyEKPRTWLNS 443
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 435 YGFSCMGYEIAGALGIWMADPARDIVCFTGDGTYMMANSELATACMMGAKFTLVITDNRGFGCINRLQmgtgGAEFNCLL 514
Cdd:PRK07789 444 GGLGTMGYAVPAAMGAKVGRPDKEVWAIDGDGCFQMTNQELATCAIEGIPIKVALINNGNLGMVRQWQ----TLFYEERY 519
|
490 500 510 520
....*....|....*....|....*....|....*....|..
gi 2564844288 515 DHT-VHENPSQI-DFVAHAASMGAKAVKAASIAELEEHLAKA 554
Cdd:PRK07789 520 SNTdLHTHSHRIpDFVKLAEAYGCVGLRCEREEDVDAVIEKA 561
|
|
| PRK07418 |
PRK07418 |
acetolactate synthase large subunit; |
2-597 |
1.55e-40 |
|
acetolactate synthase large subunit;
Pssm-ID: 236014 [Multi-domain] Cd Length: 616 Bit Score: 156.36 E-value: 1.55e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 2 TTIRLTAAQAMVKYLAAQmtpeGVPYIagcwaiFGH--GNVAGLGEALY--HQRDALPTYRGHNEQTMAHTAIAYSKQLR 77
Cdd:PRK07418 15 TPQRATGAYALMDSLKRH----GVKHI------FGYpgGAILPIYDELYkaEAEGWLKHILVRHEQGAAHAADGYARATG 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 78 RDRAMMVTSsiGPGATNMVTACALAYVNRLPVLFVPGDVfahrgPDPVLqqpenfadgtvtATDTFRPVSRYfdRITRPe 157
Cdd:PRK07418 85 KVGVCFGTS--GPGATNLVTGIATAQMDSVPMVVITGQV-----PRPAI------------GTDAFQETDIF--GITLP- 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 158 qlltaLPRAMRTMTDPADC----------------GPVTLAFCQDVQAEAYDW---------PEAFfaprvwhRRAAPPD 212
Cdd:PRK07418 143 -----IVKHSYVVRDPSDMarivaeafhiassgrpGPVLIDIPKDVGQEEFDYvpvepgsvkPPGY-------RPTVKGN 210
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 213 AGELARVAELLEGAETPVIVAGGGTHYGHATETLKDFAEAHQIPVVETQAGKSALPWDHPLNLGPIGVTGAESANTICAA 292
Cdd:PRK07418 211 PRQINAALKLIEEAERPLLYVGGGAISAGAHAELKELAERFQIPVTTTLMGKGAFDEHHPLSVGMLGMHGTAYANFAVTE 290
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 293 ADVVIGVGTRFQDFTTGSWSLFANPArKLVSLNVQAYDAMKHGAE--PLCCDAKAGLEALSAALGGKTFTAPDAAlkadW 370
Cdd:PRK07418 291 CDLLIAVGARFDDRVTGKLDEFASRA-KVIHIDIDPAEVGKNRRPdvPIVGDVRKVLVKLLERSLEPTTPPRTQA----W 365
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 371 FAKVD------PLTDAPEEDANAlPtdMQVVGAVQRSAgPDTVVMCAAGTmpgelHKLWKA----GRPGCYHMEYGFSCM 440
Cdd:PRK07418 366 LERINrwkqdyPLVVPPYEGEIY-P--QEVLLAVRDLA-PDAYYTTDVGQ-----HQMWAAqflrNGPRRWISSAGLGTM 436
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 441 GYEIAGALGIWMADPARDIVCFTGDGTYMMANSELATACMMGAKFTLVITDNRGFGCINRLQMGTGGAEFNClldhtVHE 520
Cdd:PRK07418 437 GFGMPAAMGVKVALPDEEVICIAGDASFLMNIQELGTLAQYGINVKTVIINNGWQGMVRQWQESFYGERYSA-----SNM 511
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 521 NPSQIDFVAHAASMGAKAVKAASIAELEEHLAKASDHDGVYAI----VLDTDPYPSTPHGGTWWE-VGVPEVSTRPEVNE 595
Cdd:PRK07418 512 EPGMPDFVKLAEAFGVKGMVISERDQLKDAIAEALAHDGPVLIdvhvRRDENCYPMVPPGKSNAQmVGLPEHPELALAAE 591
|
..
gi 2564844288 596 AR 597
Cdd:PRK07418 592 LI 593
|
|
| PRK06725 |
PRK06725 |
acetolactate synthase large subunit; |
30-566 |
2.78e-40 |
|
acetolactate synthase large subunit;
Pssm-ID: 180672 [Multi-domain] Cd Length: 570 Bit Score: 154.74 E-value: 2.78e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 30 GCWAIFGH--GNVAGLGEALYHQrdALPTYRGHNEQTMAHTAIAYSKQLRRDRAMMVTSsiGPGATNMVTACALAYVNRL 107
Cdd:PRK06725 29 GVTTVFGYpgGAILPVYDALYES--GLKHILTRHEQAAIHAAEGYARASGKVGVVFATS--GPGATNLVTGLADAYMDSI 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 108 PVLFVPGDVFAHrgpdpvLQQPENFADGTVTATDTfrPVSRYFDRITRPEQLltalPRAMRT---MTDPADCGPVTLAFC 184
Cdd:PRK06725 105 PLVVITGQVATP------LIGKDGFQEADVVGITV--PVTKHNYQVRDVNQL----SRIVQEafyIAESGRPGPVLIDIP 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 185 QDVQAE--AYDWPEAFFAPRvwHRRAAPPDAGELARVAELLEGAETPVIVAGGGTHYGHATETLKDFAEAHQIPVVETQA 262
Cdd:PRK06725 173 KDVQNEkvTSFYNEVVEIPG--YKPEPRPDSMKLREVAKAISKAKRPLLYIGGGVIHSGGSEELIEFARENRIPVVSTLM 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 263 GKSALPWDHPLNLGPIGVTGAESANTICAAADVVIGVGTRFQDFTTGSWSLFAnPARKLVSLNVQAYDAMKHGA--EPLC 340
Cdd:PRK06725 251 GLGAYPPGDPLFLGMLGMHGTYAANMAVTECDLLLALGVRFDDRVTGKLELFS-PHSKKVHIDIDPSEFHKNVAveYPVV 329
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 341 CDAKaglEALSAALGGKTFTAPDAalkadWFAKVDPLTDAPEEDANALPTDM---QVVGAVQRSAGPDTVVMCAAGTmpg 417
Cdd:PRK06725 330 GDVK---KALHMLLHMSIHTQTDE-----WLQKVKTWKEEYPLSYKQKESELkpqHVINLVSELTNGEAIVTTEVGQ--- 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 418 elHKLW-----KAGRPGCYHMEYGFSCMGYEIAGALGIWMADPARDIVCFTGDGTYMMANSELATACMMGAKFTLVITDN 492
Cdd:PRK06725 399 --HQMWaahfyKAKNPRTFLTSGGLGTMGFGFPAAIGAQLAKEEELVICIAGDASFQMNIQELQTIAENNIPVKVFIINN 476
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2564844288 493 RGFGCINRLQmgtggaefNCLLDHTVHEnpSQI---DFVAHAASMGAKAVKAASIAELEEHLAKASDHDGvyAIVLD 566
Cdd:PRK06725 477 KFLGMVRQWQ--------EMFYENRLSE--SKIgspDFVKVAEAYGVKGLRATNSTEAKQVMLEAFAHEG--PVVVD 541
|
|
| PRK06154 |
PRK06154 |
thiamine pyrophosphate-requiring protein; |
13-478 |
1.31e-37 |
|
thiamine pyrophosphate-requiring protein;
Pssm-ID: 235718 [Multi-domain] Cd Length: 565 Bit Score: 147.27 E-value: 1.31e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 13 VKYLAAQMTPEGVPYIAGCWA--IFGHGNVAGLgealyhqrdalPTYRGHNEQTMAHTAIAYSKQLRRDRAMMVTSSIGP 90
Cdd:PRK06154 23 AEAVAEILKEEGVELLFGFPVneLFDAAAAAGI-----------RPVIARTERVAVHMADGYARATSGERVGVFAVQYGP 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 91 GATNMVTACALAYVNRLPVLFVPGDVfahrgPDPVLQQPENFadgtvTATDTFRPVSRYFDRITRPEQLLTALPRAMRTM 170
Cdd:PRK06154 92 GAENAFGGVAQAYGDSVPVLFLPTGY-----PRGSTDVAPNF-----ESLRNYRHITKWCEQVTLPDEVPELMRRAFTRL 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 171 TDpADCGPVTLAFCQDVQAEAYDWPEAFFAPRvwHRRAAPPDAGELARVAELLEGAETPVIVAGGGTHYGHATETLKDFA 250
Cdd:PRK06154 162 RN-GRPGPVVLELPVDVLAEELDELPLDHRPS--RRSRPGADPVEVVEAAALLLAAERPVIYAGQGVLYAQATPELKELA 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 251 EAHQIPVVETQAGKSALPWDHPLNLGPIGVTGAESANTICAAADVVIGVGTrfqDFTTGSWSLFANPARKLVSLNVQAYD 330
Cdd:PRK06154 239 ELLEIPVMTTLNGKSAFPEDHPLALGSGGRARPATVAHFLREADVLFGIGC---SLTRSYYGLPMPEGKTIIHSTLDDAD 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 331 -----AMKHGaepLCCDAKAGLEALSAALGGKTFTAPD---------AALKADWFAKVDPLTDAPEEDANAlptdMQVVG 396
Cdd:PRK06154 316 lnkdyPIDHG---LVGDAALVLKQMIEELRRRVGPDRGraqqvaaeiEAVRAAWLAKWMPKLTSDSTPINP----YRVVW 388
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 397 AVQRSAGPDTVVMCA-AGTMPGELHKLWKAGRPGCYhMEYGFSC-MGYEIAGALGIWMADPARDIVCFTGDGTYMMANSE 474
Cdd:PRK06154 389 ELQHAVDIKTVIITHdAGSPRDQLSPFYVASRPGSY-LGWGKTTqLGYGLGLAMGAKLARPDALVINLWGDAAFGMTGMD 467
|
....
gi 2564844288 475 LATA 478
Cdd:PRK06154 468 FETA 471
|
|
| PRK08527 |
PRK08527 |
acetolactate synthase large subunit; |
5-578 |
2.52e-37 |
|
acetolactate synthase large subunit;
Pssm-ID: 181458 [Multi-domain] Cd Length: 563 Bit Score: 146.40 E-value: 2.52e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 5 RLTAAQAMVKYLAAqmtpEGVPyiagcwAIFGH--GNVAGLGEALYHQrdalpTYRGH----NEQTMAHTAIAYSKQLRR 78
Cdd:PRK08527 2 KLSGSQMVCEALKE----EGVK------VVFGYpgGAILNIYDEIYKQ-----NYFKHiltrHEQAAVHAADGYARASGK 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 79 DRAMMVTSsiGPGATNMVTACALAYVNRLPVLFVPGDVfahrgpdPVlqqpenfadgTVTATDTFRPVSRYfdRITRP-- 156
Cdd:PRK08527 67 VGVAIVTS--GPGFTNAVTGLATAYMDSIPLVLISGQV-------PN----------SLIGTDAFQEIDAV--GISRPcv 125
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 157 -----EQLLTALPRAMRTMTDPADCG---PVTLAFCQDVQAEAYDW--PEAFFAPRvwHRRAAPPDAGELARVAELLEGA 226
Cdd:PRK08527 126 khnylVKSIEELPRILKEAFYIARSGrpgPVHIDIPKDVTATLGEFeyPKEISLKT--YKPTYKGNSRQIKKAAEAIKEA 203
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 227 ETPVIVAGGGTHYGHATETLKDFAEAHQIPVVETQAGKSALPWDHPLNLGPIGVTGAESANTICAAADVVIGVGTRFQDF 306
Cdd:PRK08527 204 KKPLFYLGGGAILSNASEEIRELVKKTGIPAVETLMARGVLRSDDPLLLGMLGMHGSYAANMAMSECDLLISLGARFDDR 283
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 307 TTGSWSLFANPArKLVSLNVQAYDAMK--HGAEPLCCDAKAGLEALSAALGGKTFTAPDAALKA-DWFAKVDPLTdapEE 383
Cdd:PRK08527 284 VTGKLSEFAKHA-KIIHVDIDPSSISKivNADYPIVGDLKNVLKEMLEELKEENPTTYKEWREIlKRYNELHPLS---YE 359
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 384 DANALPTDMQVVGAVQRSAGPDTVVMCAAGTmpgelHKLWKA-----GRPGCYHMEYGFSCMGYEIAGALGIWMADPARD 458
Cdd:PRK08527 360 DSDEVLKPQWVIERVGELLGDDAIISTDVGQ-----HQMWVAqfypfNYPRQLATSGGLGTMGYGLPAALGAKLAVPDKV 434
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 459 IVCFTGDGTYMMANSELATACMMGAKFTLVITDNRGFGCINRLQMGTGGAEFNclldHTvhENPSQIDFVAHAASMGAKA 538
Cdd:PRK08527 435 VINFTGDGSILMNIQELMTAVEYKIPVINIILNNNFLGMVRQWQTFFYEERYS----ET--DLSTQPDFVKLAESFGGIG 508
|
570 580 590 600
....*....|....*....|....*....|....*....|....
gi 2564844288 539 VKAASIAELEEHLAKASDHDGVYAIVLDTDPY----PSTPHGGT 578
Cdd:PRK08527 509 FRVTTKEEFDKALKEALESDKVALIDVKIDRFenvlPMVPAGGA 552
|
|
| PRK08978 |
PRK08978 |
acetolactate synthase 2 catalytic subunit; Reviewed |
61-503 |
3.77e-37 |
|
acetolactate synthase 2 catalytic subunit; Reviewed
Pssm-ID: 181601 [Multi-domain] Cd Length: 548 Bit Score: 145.41 E-value: 3.77e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 61 NEQTMAHTAIAYSKQLRRDRAMMVTSsiGPGATNMVTACALAYVNRLPVLFVPGDVfahrgPDPVLqqpenfadgtvtAT 140
Cdd:PRK08978 46 HEQGAAMAAIGYARATGKVGVCIATS--GPGATNLITGLADALLDSVPVVAITGQV-----SSPLI------------GT 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 141 DTFR---------PVSRYFDRITRPEQLLTALPRAMRTMTD--PadcGPVTLAFCQDVQAEAYDWPEAFFAPRvwhrRAA 209
Cdd:PRK08978 107 DAFQeidvlglslACTKHSFLVQSLEELPEIMAEAFEIASSgrP---GPVLVDIPKDIQLAEGELEPHLTTVE----NEP 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 210 PPDAGELARVAELLEGAETPVIVAGGGTHYGHATETLKDFAEAHQIPVVETQAGKSALPWDHPLNLGPIGVTGAESANTI 289
Cdd:PRK08978 180 AFPAAELEQARALLAQAKKPVLYVGGGVGMAGAVPALREFLAATGMPAVATLKGLGAVEADHPYYLGMLGMHGTKAANLA 259
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 290 CAAADVVIGVGTRFQDFTTGSWSLFAnPARKLVSLNVQAY--DAMKHGAEPLCCDAKAGLEALSAALGGKTFTAPDAALK 367
Cdd:PRK08978 260 VQECDLLIAVGARFDDRVTGKLNTFA-PHAKVIHLDIDPAeiNKLRQAHVALQGDLNALLPALQQPLNIDAWRQHCAQLR 338
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 368 AD--WFAkvdpltDAPEEDANAlPTdmqVVGAVQRSAGPDTVVMCAAGTmpgelHKLWKAgrpgcYHMEY---------- 435
Cdd:PRK08978 339 AEhaWRY------DHPGEAIYA-PA---LLKQLSDRKPADTVVTTDVGQ-----HQMWVA-----QHMRFtrpenfitss 398
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2564844288 436 GFSCMGYEIAGALGIWMADPARDIVCFTGDGTYMMANSELATACMMGAKFTLVITDNrgfgciNRLQM 503
Cdd:PRK08978 399 GLGTMGFGLPAAIGAQVARPDDTVICVSGDGSFMMNVQELGTIKRKQLPVKIVLLDN------QRLGM 460
|
|
| PRK06112 |
PRK06112 |
acetolactate synthase catalytic subunit; Validated |
80-569 |
8.15e-37 |
|
acetolactate synthase catalytic subunit; Validated
Pssm-ID: 235700 [Multi-domain] Cd Length: 578 Bit Score: 144.90 E-value: 8.15e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 80 RAMMVTSSIGPGATNMVTACALAYVNRLPVLFVPGDVFAHRGPDPVLQQPENFAdgtvtatdTFRPVSRYFDRITRPEQL 159
Cdd:PRK06112 74 KVAVVTAQNGPAATLLVAPLAEALKASVPIVALVQDVNRDQTDRNAFQELDHIA--------LFQSCTKWVRRVTVAERI 145
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 160 LTALPRAMRTMTDpADCGPVTLAFCQDVQAEAYDWPEAffaPRV-----WHRRAAPPDAGELARVAELLEGAETPVIVAG 234
Cdd:PRK06112 146 DDYVDQAFTAATS-GRPGPVVLLLPADLLTAAAAAPAA---PRSnslghFPLDRTVPAPQRLAEAASLLAQAQRPVVVAG 221
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 235 GGTHYGHATETLKDFAEAHQIPVVETQAGKSALPWDHPLNLGPIG-VTGAESAN----TICAAADVVIGVGTRFQDFTTG 309
Cdd:PRK06112 222 GGVHISGASAALAALQSLAGLPVATTNMGKGAVDETHPLSLGVVGsLMGPRSPGrhlrDLVREADVVLLVGTRTNQNGTD 301
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 310 SWSLFANPARkLVSLNVQA------YDAMKhgaepLCCDAKAGLEALSAALGGKTFT-------APDAALKADWFAKVDP 376
Cdd:PRK06112 302 SWSLYPEQAQ-YIHIDVDGeevgrnYEALR-----LVGDARLTLAALTDALRGRDLAaragrraALEPAIAAGREAHRED 375
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 377 LTDAPEEDANALPTDmQVVGAVQRSAGPDTVVMCAAGTMPGELHKLWKAGRPGC-YHMEYGFSCMGYEIAGALGIWMADP 455
Cdd:PRK06112 376 SAPVALSDASPIRPE-RIMAELQAVLTGDTIVVADASYSSIWVANFLTARRAGMrFLTPRGLAGLGWGVPMAIGAKVARP 454
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 456 ARDIVCFTGDGTYMMANSELATACMMGAKFTLVITDNRGFGcinrLQMgtgGAEFNCLLDHTVHENPSQIDFVAHAASMG 535
Cdd:PRK06112 455 GAPVICLVGDGGFAHVWAELETARRMGVPVTIVVLNNGILG----FQK---HAETVKFGTHTDACHFAAVDHAAIARACG 527
|
490 500 510
....*....|....*....|....*....|....
gi 2564844288 536 AKAVKAASIAELEEHLAKASDHDGVYAIVLDTDP 569
Cdd:PRK06112 528 CDGVRVEDPAELAQALAAAMAAPGPTLIEVITDP 561
|
|
| PRK06466 |
PRK06466 |
acetolactate synthase 3 large subunit; |
6-554 |
1.10e-36 |
|
acetolactate synthase 3 large subunit;
Pssm-ID: 180578 [Multi-domain] Cd Length: 574 Bit Score: 144.50 E-value: 1.10e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 6 LTAAQAMVKYLAaqmtPEGVPYIAGcwaiFGHGNVAGLGEALYHQrDALPTYRGHNEQTMAHTAIAYSKQLRRDRAMMVT 85
Cdd:PRK06466 4 LSGAEMLVRALR----DEGVEYIYG----YPGGAVLHIYDALFKQ-DKVEHILVRHEQAATHMADGYARATGKTGVVLVT 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 86 SsiGPGATNMVTACALAYVNRLPVLFVPGDVFAHRGPDPVLQQpenfadgtvtaTDTF---RPVSRYFDRITRPEQLLTA 162
Cdd:PRK06466 75 S--GPGATNAITGIATAYMDSIPMVVLSGQVPSTLIGEDAFQE-----------TDMVgisRPIVKHSFMVKHASEIPEI 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 163 LPRAMrTMTDPADCGPVTLAFCQDVQAEA----YDWPEaffapRVWHRRAAPP---DAGELARVAELLEGAETPVIVAGG 235
Cdd:PRK06466 142 IKKAF-YIAQSGRPGPVVVDIPKDMTNPAekfeYEYPK-----KVKLRSYSPAvrgHSGQIRKAVEMLLAAKRPVIYSGG 215
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 236 GTHYGHATETLKDFAEAHQIPVVETQAGKSALPWDHPLNLGPIGVTGAESANTICAAADVVIGVGTRFQDFTTGSWSLFA 315
Cdd:PRK06466 216 GVVLGNASALLTELAHLLNLPVTNTLMGLGGFPGTDRQFLGMLGMHGTYEANMAMHHADVILAVGARFDDRVTNGPAKFC 295
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 316 nPARKLVSLNVQAYDAMKHGAE--PLCCDAKAGLEALSAALgGKTFTAPDAALKADWFAKVDPLTDAP-----EEDANAL 388
Cdd:PRK06466 296 -PNAKIIHIDIDPASISKTIKAdiPIVGPVESVLTEMLAIL-KEIGEKPDKEALAAWWKQIDEWRGRHglfpyDKGDGGI 373
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 389 PTDMQVVGAVQRSAGPDTVVMCAAG--TMPGELHklWKAGRPGCYHMEYGFSCMGYEIAGALGIWMADPARDIVCFTGDG 466
Cdd:PRK06466 374 IKPQQVVETLYEVTNGDAYVTSDVGqhQMFAAQY--YKFNKPNRWINSGGLGTMGFGLPAAMGVKLAFPDQDVACVTGEG 451
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 467 TYMMANSELATACMMGAKFTLVITDNRGFGCINRLQ-MGTGGAefnclldHTVHENPSQIDFVAHAASMGAKAVKAASIA 545
Cdd:PRK06466 452 SIQMNIQELSTCLQYGLPVKIINLNNGALGMVRQWQdMQYEGR-------HSHSYMESLPDFVKLAEAYGHVGIRITDLK 524
|
....*....
gi 2564844288 546 ELEEHLAKA 554
Cdd:PRK06466 525 DLKPKLEEA 533
|
|
| TPP_enzyme_C |
pfam02775 |
Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; |
411-564 |
1.40e-36 |
|
Thiamine pyrophosphate enzyme, C-terminal TPP binding domain;
Pssm-ID: 460689 [Multi-domain] Cd Length: 151 Bit Score: 133.48 E-value: 1.40e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 411 AAGTMPGELHKLWKAGRPGCYHMEYGFSCMGYEIAGALGIWMADPARDIVCFTGDGTYMMANSELATACMMGAKFTLVIT 490
Cdd:pfam02775 1 DIGCHQMWAAQYYRFRPPRRYLTSGGLGTMGYGLPAAIGAKLARPDRPVVAIAGDGGFQMNLQELATAVRYNLPITVVVL 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2564844288 491 DNRGFGCINRLQMGTGGAEFNclldHTVHENPSQIDFVAHAASMGAKAVKAASIAELEEHLAKASDHDGVYAIV 564
Cdd:pfam02775 81 NNGGYGMTRGQQTPFGGGRYS----GPSGKILPPVDFAKLAEAYGAKGARVESPEELEEALKEALEHDGPALID 150
|
|
| PRK07524 |
PRK07524 |
5-guanidino-2-oxopentanoate decarboxylase; |
89-566 |
4.19e-36 |
|
5-guanidino-2-oxopentanoate decarboxylase;
Pssm-ID: 236041 [Multi-domain] Cd Length: 535 Bit Score: 142.42 E-value: 4.19e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 89 GPGATNMVTACALAYVNRLPVLFVP----------GDVFAHRGPDpvlQQpenfadgtvtatDTFRPVSRYFDRITRPEQ 158
Cdd:PRK07524 73 GPGMTNIATAMGQAYADSIPMLVISsvnrraslgkGRGKLHELPD---QR------------AMVAGVAAFSHTLMSAED 137
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 159 LLTALPRAMRTMtDPADCGPVTLAFCQDVQAE--AYDWPeaffAPRVWHRRAAPPDAGeLARVAELLEGAETPVIVAGGG 236
Cdd:PRK07524 138 LPEVLARAFAVF-DSARPRPVHIEIPLDVLAApaDHLLP----APPTRPARPGPAPAA-LAQAAERLAAARRPLILAGGG 211
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 237 THygHATETLKDFAEAHQIPVVETQAGKSALPWDHPLNLGpiGVTGAESANTICAAADVVIGVGTRFQD------FTTGs 310
Cdd:PRK07524 212 AL--AAAAALRALAERLDAPVALTINAKGLLPAGHPLLLG--ASQSLPAVRALIAEADVVLAVGTELGEtdydvyFDGG- 286
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 311 wslFANPARkLVSLNVQAYDAMKH--GAEPLCCDAKAGLEALSAALGGKTFTAPDA---------ALKADWFAKVDPLTD 379
Cdd:PRK07524 287 ---FPLPGE-LIRIDIDPDQLARNypPALALVGDARAALEALLARLPGQAAAADWGaarvaalrqALRAEWDPLTAAQVA 362
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 380 APEEDANALPtDMQVVGavqrsagpDTVVMCAAGTMpgelhkLWKAGRPGCY-HMEYGFSCMGYEIAGALGIWMADPARD 458
Cdd:PRK07524 363 LLDTILAALP-DAIFVG--------DSTQPVYAGNL------YFDADAPRRWfNASTGYGTLGYGLPAAIGAALGAPERP 427
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 459 IVCFTGDGTYMMANSELATACMMGAKFTLVITDNRGFGCINRlqmgtggaefnCLLDHTVHE---NPSQIDFVAHAASMG 535
Cdd:PRK07524 428 VVCLVGDGGLQFTLPELASAVEADLPLIVLLWNNDGYGEIRR-----------YMVARDIEPvgvDPYTPDFIALARAFG 496
|
490 500 510
....*....|....*....|....*....|.
gi 2564844288 536 AKAVKAASIAELEEHLAKASDHDGVYAIVLD 566
Cdd:PRK07524 497 CAAERVADLEQLQAALRAAFARPGPTLIEVD 527
|
|
| PRK06882 |
PRK06882 |
acetolactate synthase 3 large subunit; |
5-554 |
1.01e-35 |
|
acetolactate synthase 3 large subunit;
Pssm-ID: 168717 [Multi-domain] Cd Length: 574 Bit Score: 141.59 E-value: 1.01e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 5 RLTAAQAMVKYLaaqmTPEGVPYIAGcwaiFGHGNVAGLGEALyHQRDALPTYRGHNEQTMAHTAIAYSKQLRRDRAMMV 84
Cdd:PRK06882 3 KLSGAEMVVQSL----RDEGVEYVFG----YPGGSVLDIYDAI-HTLGGIEHVLVRHEQAAVHMADGYARSTGKVGCVLV 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 85 TSsiGPGATNMVTACALAYVNRLPVLFVPGDVfahrgpdpvlqqPENfadgtVTATDTF---------RPVSRYFDRITR 155
Cdd:PRK06882 74 TS--GPGATNAITGIATAYTDSVPLVILSGQV------------PSN-----LIGTDAFqecdmlgisRPVVKHSFIVKN 134
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 156 PEQLLTALPRAMrTMTDPADCGPVTLAFCQDVQAEA----YDWPEaffapRVWHRRAAPPDAGELARVAELLEG---AET 228
Cdd:PRK06882 135 AEDIPSTIKKAF-YIASTGRPGPVVIDIPKDMVNPAnkftYEYPE-----EVSLRSYNPTVQGHKGQIKKALKAllvAKK 208
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 229 PVIVAGGGTHYGHATETLKDFAEAHQIPVVETQAGKSALPWDHPLNLGPIGVTGAESANTICAAADVVIGVGTRFQDFTT 308
Cdd:PRK06882 209 PVLFVGGGVITAECSEQLTQFAQKLNLPVTSSLMGLGAYPSTDKQFLGMLGMHGTYEANNAMHESDLILGIGVRFDDRTT 288
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 309 GSWSLFAnPARKLVSLNVQAYDAMKH--GAEPLCCDAKAGLEALSAALGGKTFTAPDAALKaDWFAKVDPLTDAP---EE 383
Cdd:PRK06882 289 NNLAKYC-PNAKVIHIDIDPTSISKNvpAYIPIVGSAKNVLEEFLSLLEEENLAKSQTDLT-AWWQQINEWKAKKcleFD 366
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 384 DANALPTDMQVVGAVQRSAGPDTVVMCAAGT--MPGELHklWKAGRPGCYHMEYGFSCMGYEIAGALGIWMADPARDIVC 461
Cdd:PRK06882 367 RTSDVIKPQQVVEAIYRLTNGDAYVASDVGQhqMFAALH--YPFDKPRRWINSGGAGTMGFGLPAAIGVKFAHPEATVVC 444
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 462 FTGDGTYMMANSELATACMMGAKFTLVITDNRGFGCINRLQ--MGTGgaefncllDHTVHENPSQIDFVAHAASMGAKAV 539
Cdd:PRK06882 445 VTGDGSIQMNIQELSTAKQYDIPVVIVSLNNRFLGMVKQWQdlIYSG--------RHSQVYMNSLPDFAKLAEAYGHVGI 516
|
570
....*....|....*
gi 2564844288 540 KAASIAELEEHLAKA 554
Cdd:PRK06882 517 QIDTPDELEEKLTQA 531
|
|
| PRK07525 |
PRK07525 |
sulfoacetaldehyde acetyltransferase; Validated |
1-556 |
6.03e-35 |
|
sulfoacetaldehyde acetyltransferase; Validated
Pssm-ID: 236042 [Multi-domain] Cd Length: 588 Bit Score: 139.75 E-value: 6.03e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 1 MTTIRLTAAQAMVKYLAAqmtpEGVPYIAGCwaifghgnvagLGEALYHQRDALPT-----YRGHNEQTMAHTAIAYSKQ 75
Cdd:PRK07525 1 MGKMKMTPSEAFVETLQA----HGITHAFGI-----------IGSAFMDASDLFPPagirfIDVAHEQNAGHMADGYTRV 65
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 76 lrRDRAMMVTSSIGPGATNMVTACALAYVNRLPVLFVpgdvfahrgpdpvlqQPEnfadgtvTATDT------------- 142
Cdd:PRK07525 66 --TGRMGMVIGQNGPGITNFVTAVATAYWAHTPVVLV---------------TPQ-------AGTKTigqggfqeaeqmp 121
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 143 -FRPVSRYFDRITRP----EQLLTALPRAMRTMtdpadcGPVTLA-----FCQDVQAEAYdwpeaffAPRVWHRRAAPPD 212
Cdd:PRK07525 122 mFEDMTKYQEEVRDPsrmaEVLNRVFDKAKRES------GPAQINiprdyFYGVIDVEIP-------QPVRLERGAGGEQ 188
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 213 AgeLARVAELLEGAETPVIVAGGGTHYGHATETLKDFAEAHQIPVVETQAGKSALPWDHPLNLGPIGVTGAESANTICAA 292
Cdd:PRK07525 189 S--LAEAAELLSEAKFPVILSGAGVVLSDAIEECKALAERLDAPVACGYLHNDAFPGSHPLWVGPLGYNGSKAAMELIAK 266
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 293 ADVVIGVGTRFQDFTT------GSWSLFA-------NPAR----KLVSLNvqaydamkhgaepLCCDAKAGLEALSAALG 355
Cdd:PRK07525 267 ADVVLALGTRLNPFGTlpqygiDYWPKDAkiiqvdiNPDRigltKKVSVG-------------ICGDAKAVARELLARLA 333
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 356 GKtfTAPD----------AALKADWF--------AKVDPLTDAPEEDANALPTDM---QVVGAVQRSAGPDTVV------ 408
Cdd:PRK07525 334 ER--LAGDagreerkaliAAEKSAWEqelsswdhEDDDPGTDWNEEARARKPDYMhprQALREIQKALPEDAIVstdign 411
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 409 MCAAGTMpgelHKLWKAGRPGCYHMEYGfSCmGYEIAGALGIWMADPARDIVCFTGDGTYMMANSELATACMMGAKFTLV 488
Cdd:PRK07525 412 NCSIANS----YLRFEKGRKYLAPGSFG-NC-GYAFPAIIGAKIACPDRPVVGFAGDGAWGISMNEVMTAVRHNWPVTAV 485
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2564844288 489 ITDNRGFGCINRLQ--------MGTggaefnclldhtvhENPSQIDFVAHAASMGAKAVKAASIAELEEHLAKASD 556
Cdd:PRK07525 486 VFRNYQWGAEKKNQvdfynnrfVGT--------------ELDNNVSYAGIAEAMGAEGVVVDTQEELGPALKRAID 547
|
|
| PRK08979 |
PRK08979 |
acetolactate synthase 3 large subunit; |
6-554 |
1.90e-34 |
|
acetolactate synthase 3 large subunit;
Pssm-ID: 181602 [Multi-domain] Cd Length: 572 Bit Score: 138.03 E-value: 1.90e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 6 LTAAQAMVKYLaaqmTPEGVPYIAGcwaiFGHGNVAGLGEALyHQRDALPTYRGHNEQTMAHTAIAYSKQLRRDRAMMVT 85
Cdd:PRK08979 4 LSGASMIVRSL----IDEGVKHIFG----YPGGSVLDIYDAL-HEKSGIEHILVRHEQAAVHMADGYARATGKVGVVLVT 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 86 SsiGPGATNMVTACALAYVNRLPVLFVPGDVfahrgpdpvlqqPENfadgtVTATDTF---------RPVSRYFDRITRP 156
Cdd:PRK08979 75 S--GPGATNTITGIATAYMDSIPMVVLSGQV------------PSN-----LIGNDAFqecdmigisRPVVKHSFLVKDA 135
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 157 EQLLTALPRAMRTMTDpADCGPVTLAFCQDVQAEA----YDWPEAffaprVWHRRAAPPDAG---ELARVAELLEGAETP 229
Cdd:PRK08979 136 EDIPEIIKKAFYIAST-GRPGPVVIDLPKDCLNPAilhpYEYPES-----IKMRSYNPTTSGhkgQIKRGLQALLAAKKP 209
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 230 VIVAGGGTHYGHATETLKDFAEAHQIPVVETQAGKSALPWDHPLNLGPIGVTGAESANTICAAADVVIGVGTRFQDFTTG 309
Cdd:PRK08979 210 VLYVGGGAIISGADKQILQLAEKLNLPVVSTLMGLGAFPGTHKNSLGMLGMHGRYEANMAMHNADLIFGIGVRFDDRTTN 289
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 310 SWSLFAnPARKLVSLNVQAYDAMKHGAE--PLCCDAKAGLEALSAALGGKTFTAPDAALKADWfakvDPLTDAPEEDANA 387
Cdd:PRK08979 290 NLEKYC-PNATILHIDIDPSSISKTVRVdiPIVGSADKVLDSMLALLDESGETNDEAAIASWW----NEIEVWRSRNCLA 364
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 388 LPTD------MQVVGAVQRSAGPDTVVMCAAGTmpgelHKLWKA-----GRPGCYHMEYGFSCMGYEIAGALGIWMADPA 456
Cdd:PRK08979 365 YDKSserikpQQVIETLYKLTNGDAYVASDVGQ-----HQMFAAlyypfDKPRRWINSGGLGTMGFGLPAAMGVKFAMPD 439
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 457 RDIVCFTGDGTYMMANSELATACMMGAKFTLVITDNRGFGCINRLQ-MGTGGAEFNCLLDhtvhenpSQIDFVAHAASMG 535
Cdd:PRK08979 440 ETVVCVTGDGSIQMNIQELSTALQYDIPVKIINLNNRFLGMVKQWQdMIYQGRHSHSYMD-------SVPDFAKIAEAYG 512
|
570
....*....|....*....
gi 2564844288 536 AKAVKAASIAELEEHLAKA 554
Cdd:PRK08979 513 HVGIRISDPDELESGLEKA 531
|
|
| PRK07064 |
PRK07064 |
thiamine pyrophosphate-binding protein; |
86-566 |
2.47e-34 |
|
thiamine pyrophosphate-binding protein;
Pssm-ID: 180820 [Multi-domain] Cd Length: 544 Bit Score: 137.43 E-value: 2.47e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 86 SSIGPGATNMVTACALAYVNRLPVLFVPGDV----------FAHRGPDpvlqQPenfadgtvtatDTFRPVSRYFDRITR 155
Cdd:PRK07064 72 TSTGTGAGNAAGALVEALTAGTPLLHITGQIetpyldqdlgYIHEAPD----QL-----------TMLRAVSKAAFRVRS 136
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 156 PEQLLTALPRAMRT-MTDPadCGPVTLAFCQDVQAEAYDWPEAFFAPRVwhrRAAPPDAGELARVAELLEGAETPVIVAG 234
Cdd:PRK07064 137 AETALATIREAVRVaLTAP--TGPVSVEIPIDIQAAEIELPDDLAPVHV---AVPEPDAAAVAELAERLAAARRPLLWLG 211
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 235 GGTHygHATETLKDFAEAhQIPVVETQAGKSALPWDHPLNLGPIGVTGAESAntICAAADVVIGVGTRFQDFTTGSWSLf 314
Cdd:PRK07064 212 GGAR--HAGAEVKRLVDL-GFGVVTSTQGRGVVPEDHPASLGAFNNSAAVEA--LYKTCDLLLVVGSRLRGNETLKYSL- 285
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 315 ANPaRKLVSLNVqayDAMKHG-----AEPLCCDAKAGLEALSAALGGKtfTAPDAALKADwfakvdpLTDAPEEDANALP 389
Cdd:PRK07064 286 ALP-RPLIRVDA---DAAADGrgypnDLFVHGDAARVLARLADRLEGR--LSVDPAFAAD-------LRAAREAAVADLR 352
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 390 TDM----QVVGAVQRSAGPDTVVMCAAgTMPGEL--HKLWKAGRPGC-YHMEYGFSCMGyeIAGALGIWMADPARDIVCF 462
Cdd:PRK07064 353 KGLgpyaKLVDALRAALPRDGNWVRDV-TISNSTwgNRLLPIFEPRAnVHALGGGIGQG--LAMAIGAALAGPGRKTVGL 429
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 463 TGDGTYMMANSELATACMMGAKFTLVITDNRGFGCINRLQ-MGTGGAE-FNCLldHTvhenPsqiDFVAHAASMGAKAVK 540
Cdd:PRK07064 430 VGDGGLMLNLGELATAVQENANMVIVLMNDGGYGVIRNIQdAQYGGRRyYVEL--HT----P---DFALLAASLGLPHWR 500
|
490 500
....*....|....*....|....*.
gi 2564844288 541 AASIAELEEHLAKASDHDGVYAIVLD 566
Cdd:PRK07064 501 VTSADDFEAVLREALAKEGPVLVEVD 526
|
|
| PRK07710 |
PRK07710 |
acetolactate synthase large subunit; |
34-566 |
3.76e-34 |
|
acetolactate synthase large subunit;
Pssm-ID: 236076 [Multi-domain] Cd Length: 571 Bit Score: 137.20 E-value: 3.76e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 34 IFGH--GNVAGLGEALYhqRDALPTYRGHNEQTMAHTAIAYSKQLRRDRAMMVTSsiGPGATNMVTACALAYVNRLPVLF 111
Cdd:PRK07710 34 IFGYpgGAVLPLYDALY--DCGIPHILTRHEQGAIHAAEGYARISGKPGVVIATS--GPGATNVVTGLADAMIDSLPLVV 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 112 VPGDVFAhrgpdpvlqqpenfadgTVTATDTFR---------PVSRYFDRITRPEQLLTALPRAMRTMTDpADCGPVTLA 182
Cdd:PRK07710 110 FTGQVAT-----------------SVIGSDAFQeadimgitmPVTKHNYQVRKASDLPRIIKEAFHIATT-GRPGPVLID 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 183 FCQDVQAE--AYDWPEAFFAPRvwHRRAAPPDAGELARVAELLEGAETPVIVAGGGTHYGHATETLKDFAEAHQIPVVET 260
Cdd:PRK07710 172 IPKDMVVEegEFCYDVQMDLPG--YQPNYEPNLLQIRKLVQAVSVAKKPVILAGAGVLHAKASKELTSYAEQQEIPVVHT 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 261 QAGKSALPWDHPLNLGPIGVTGAESANTICAAADVVIGVGTRFQDFTTGSWSLFAnPARKLVSLNVQAYDAMK--HGAEP 338
Cdd:PRK07710 250 LLGLGGFPADHPLFLGMAGMHGTYTANMALYECDLLINIGARFDDRVTGNLAYFA-KEATVAHIDIDPAEIGKnvPTEIP 328
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 339 LCCDAKAGLEALSAALGGKTFTAPDAALKADWFAKVdPLTDAPEEDAnalPTDMQVVGAVQRSAGPDTVVMCAAGTmpge 418
Cdd:PRK07710 329 IVADAKQALQVLLQQEGKKENHHEWLSLLKNWKEKY-PLSYKRNSES---IKPQKAIEMLYEITKGEAIVTTDVGQ---- 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 419 lHKLWKA-----GRPGCYHMEYGFSCMGYEIAGALGIWMADPARDIVCFTGDGTYMMANSELATACMMGAKFTLVITDNR 493
Cdd:PRK07710 401 -HQMWAAqyypfKTPDKWVTSGGLGTMGFGLPAAIGAQLAKPDETVVAIVGDGGFQMTLQELSVIKELSLPVKVVILNNE 479
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2564844288 494 GFGCINRLQmgtggAEF-NCLLDHTVHenPSQIDFVAHAASMGAKAVKAASIAELEEHLAKASDHDGvyAIVLD 566
Cdd:PRK07710 480 ALGMVRQWQ-----EEFyNQRYSHSLL--SCQPDFVKLAEAYGIKGVRIDDELEAKEQLQHAIELQE--PVVID 544
|
|
| PRK06965 |
PRK06965 |
acetolactate synthase 3 catalytic subunit; Validated |
6-502 |
1.32e-33 |
|
acetolactate synthase 3 catalytic subunit; Validated
Pssm-ID: 180780 [Multi-domain] Cd Length: 587 Bit Score: 135.70 E-value: 1.32e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 6 LTAAQAMVKYLAAqmtpEGVPYIagcWAIFGhGNVAGLGEALYHQrDALPTYRGHNEQTMAHTAIAYSKQLRRDRAMMVT 85
Cdd:PRK06965 21 SIGAEILMKALAA----EGVEFI---WGYPG-GAVLYIYDELYKQ-DKIQHVLVRHEQAAVHAADGYARATGKVGVALVT 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 86 SsiGPGATNMVTACALAYVNRLPVLFVPGDVfahrgPDPVLQQPENFADGTVTATdtfRPVSRYFDRITRPEQLLTALPR 165
Cdd:PRK06965 92 S--GPGVTNAVTGIATAYMDSIPMVVISGQV-----PTAAIGQDAFQECDTVGIT---RPIVKHNFLVKDVRDLAETVKK 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 166 AMRtMTDPADCGPVTLAFCQDV--QAEAYDWPEAffaprVWHRRAAPPD---AGELARVAELLEGAETPVIVAGGGTHYG 240
Cdd:PRK06965 162 AFY-IARTGRPGPVVVDIPKDVskTPCEYEYPKS-----VEMRSYNPVTkghSGQIRKAVSLLLSAKRPYIYTGGGVILA 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 241 HATETLKDFAEAHQIPVVETQAGKSALPWDHPLNLGPIGVTGAESANTICAAADVVIGVGTRFQDFTTGSWSLFANPARK 320
Cdd:PRK06965 236 NASRELRQLADLLGYPVTNTLMGLGAYPASDKKFLGMLGMHGTYEANMAMQHCDVLIAIGARFDDRVIGNPAHFASRPRK 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 321 LVSLNVQAYDAMKHGAE--PLCCDAKAGLEALSAALGGKTfTAPDAALKADWFAKVDPL--TDAPEEDANALPTDMQ-VV 395
Cdd:PRK06965 316 IIHIDIDPSSISKRVKVdiPIVGDVKEVLKELIEQLQTAE-HGPDADALAQWWKQIEGWrsRDCLKYDRESEIIKPQyVV 394
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 396 GAVQRSAGPDTVVMCAAGTmpgelHKLWKA-----GRPGCYHMEYGFSCMGYEIAGALGIWMADPARDIVCFTGDGTYMM 470
Cdd:PRK06965 395 EKLWELTDGDAFVCSDVGQ-----HQMWAAqfyrfNEPRRWINSGGLGTMGVGLPYAMGIKMAHPDDDVVCITGEGSIQM 469
|
490 500 510
....*....|....*....|....*....|..
gi 2564844288 471 ANSELATACMMGAKFTLVITDNRGFGCINRLQ 502
Cdd:PRK06965 470 CIQELSTCLQYDTPVKIISLNNRYLGMVRQWQ 501
|
|
| PRK05858 |
PRK05858 |
acetolactate synthase; |
51-466 |
2.42e-33 |
|
acetolactate synthase;
Pssm-ID: 235629 [Multi-domain] Cd Length: 542 Bit Score: 134.46 E-value: 2.42e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 51 RDALPTYRGHNEQTMAHTAIAYSKQLRRDRAMMVTSsiGPGATNMVTACALAYVNRLPVLFVPGdvfahRGPDpvlqqpE 130
Cdd:PRK05858 40 EEGIRLIDVRHEQTAAFAAEAWAKLTRVPGVAVLTA--GPGVTNGMSAMAAAQFNQSPLVVLGG-----RAPA------L 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 131 NFADGTVTATD---TFRPVSRYFDRITRPEQLLTALPRAMRTMTDPADcGPVTLAFCQDV---QAEAYDWPEAFFAPRvw 204
Cdd:PRK05858 107 RWGMGSLQEIDhvpFVAPVTKFAATAQSAENAGRLVDQALQAAVTPHR-GPVFVDFPMDHafsMADDDGRPGALTELP-- 183
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 205 hrRAAPPDAGELARVAELLEGAETPVIVAGGGTHYGHATETLKDFAEAHQIPVVETQAGKSALPWDHPLnlgpiGVTGAE 284
Cdd:PRK05858 184 --AGPTPDPDALARAAGLLAEAQRPVIMAGTDVWWGHAEAALLRLAEELGIPVLMNGMGRGVVPADHPL-----AFSRAR 256
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 285 SAntICAAADVVIGVGTRFqDFTTGsWSLFANPARkLVSLnVQAYDAMKHGAEPlccdAKAGLEALSAALGGKTFTAPDA 364
Cdd:PRK05858 257 GK--ALGEADVVLVVGVPM-DFRLG-FGVFGGTAQ-LVHV-DDAPPQRAHHRPV----AAGLYGDLSAILSALAGAGGDR 326
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 365 ALKADWFAKV-DPLTDAPEEDANALPTD------MQVVGAVQRSAGPDTVVMCAAGTMPGELHKLWKAGRPGCYHMEYGF 437
Cdd:PRK05858 327 TDHQGWIEELrTAETAARARDAAELADDrdpihpMRVYGELAPLLDRDAIVIGDGGDFVSYAGRYIDPYRPGCWLDPGPF 406
|
410 420
....*....|....*....|....*....
gi 2564844288 438 SCMGYEIAGALGIWMADPARDIVCFTGDG 466
Cdd:PRK05858 407 GCLGTGPGYALAARLARPSRQVVLLQGDG 435
|
|
| PRK08199 |
PRK08199 |
thiamine pyrophosphate protein; Validated |
49-574 |
1.49e-32 |
|
thiamine pyrophosphate protein; Validated
Pssm-ID: 181285 [Multi-domain] Cd Length: 557 Bit Score: 132.31 E-value: 1.49e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 49 HQRDALPTYRGHNEQTMAHTAIAYSKQLRRDRAMMVTSsiGPGATNMVTACALAYVNRLP-VLFVpGDV-FAHRGPdpvl 126
Cdd:PRK08199 42 HDETDIRVIVCRQEGGAAMMAEAYGKLTGRPGICFVTR--GPGATNASIGVHTAFQDSTPmILFV-GQVaRDFRER---- 114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 127 qqpENFADGTVTATdtFRPVSRYFDRITRPEQLLTALPRAMRTMTD--PadcGPVTLAFCQDVQAEAYDWPEAffaPRVw 204
Cdd:PRK08199 115 ---EAFQEIDYRRM--FGPMAKWVAEIDDAARIPELVSRAFHVATSgrP---GPVVLALPEDVLSETAEVPDA---PPY- 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 205 HRRAAPPDAGELARVAELLEGAETPVIVAGGGTHYGHATETLKDFAEAHQIPVVETQAGKSALPWDHPLNLGPIGV-TGA 283
Cdd:PRK08199 183 RRVAAAPGAADLARLAELLARAERPLVILGGSGWTEAAVADLRAFAERWGLPVACAFRRQDLFDNRHPNYAGDLGLgINP 262
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 284 ESANTIcAAADVVIGVGTRFQDFTTGSWSLFA--NPARKLVSLNVQAYDAMK--HGAEPLCCDAKAGLEALSAAlggktf 359
Cdd:PRK08199 263 ALAARI-READLVLAVGTRLGEVTTQGYTLLDipVPRQTLVHVHPDAEELGRvyRPDLAIVADPAAFAAALAAL------ 335
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 360 tapDAALKADWFAKVDPLTDAPEEDANALPT----DM-QVVGAVQRSAGPDTVVMCAAGTMPGELHKLWKAGRpgcYHME 434
Cdd:PRK08199 336 ---EPPASPAWAEWTAAAHADYLAWSAPLPGpgavQLgEVMAWLRERLPADAIITNGAGNYATWLHRFFRFRR---YRTQ 409
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 435 YGFSC--MGYEIAGALGIWMADPARDIVCFTGDGTYMMANSELATACMMGAKFTLVITDNRGFGCINRLQ--------MG 504
Cdd:PRK08199 410 LAPTSgsMGYGLPAAIAAKLLFPERTVVAFAGDGCFLMNGQELATAVQYGLPIIVIVVNNGMYGTIRMHQereypgrvSG 489
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2564844288 505 TGgaefnclLDhtvheNPsqiDFVAHAASMGAKAVKAASIAELEEHLAKASDHdGVYAIV-LDTDPYPSTP 574
Cdd:PRK08199 490 TD-------LT-----NP---DFAALARAYGGHGETVERTEDFAPAFERALAS-GKPALIeIRIDPEAITP 544
|
|
| PRK07979 |
PRK07979 |
acetolactate synthase 3 large subunit; |
44-557 |
3.16e-32 |
|
acetolactate synthase 3 large subunit;
Pssm-ID: 181185 [Multi-domain] Cd Length: 574 Bit Score: 131.51 E-value: 3.16e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 44 GEALYHQRDALPTYRG------HNEQTMAHTAIAYSKQLRRDRAMMVTSsiGPGATNMVTACALAYVNRLPVLFVPGDVF 117
Cdd:PRK07979 27 GGAVLDIYDALHTVGGidhvlvRHEQAAVHMADGLARATGEVGVVLVTS--GPGATNAITGIATAYMDSIPLVVLSGQVA 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 118 AHrgpdpvLQQPENFADGTVTATDtfRPVSRYFDRITRPEQLLTALPRAMrTMTDPADCGPVTLAFCQDVQAEA----YD 193
Cdd:PRK07979 105 TS------LIGYDAFQECDMVGIS--RPVVKHSFLVKQTEDIPQVLKKAF-WLAASGRPGPVVVDLPKDILNPAnklpYV 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 194 WPEAF----FAPRVWHRRaappdaGELARVAELLEGAETPVIVAGGGTHYGHATETLKDFAEAHQIPVVETQAGKSALPW 269
Cdd:PRK07979 176 WPESVsmrsYNPTTQGHK------GQIKRALQTLVAAKKPVVYVGGGAINAACHQQLKELVEKLNLPVVSSLMGLGAFPA 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 270 DHPLNLGPIGVTGAESANTICAAADVVIGVGTRFQDFTTGSWSLFAnPARKLVSLNVQAYDAMKHGAE--PLCCDAKAGL 347
Cdd:PRK07979 250 THRQSLGMLGMHGTYEANMTMHNADVIFAVGVRFDDRTTNNLAKYC-PNATVLHIDIDPTSISKTVTAdiPIVGDARQVL 328
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 348 EALSAALGGKTFTAPDAALKaDWFAKVDPL--TDAPEEDANALPTDMQ-VVGAVQRSAGPDTVVMCAAGTmpgelHKLWK 424
Cdd:PRK07979 329 EQMLELLSQESAHQPLDEIR-DWWQQIEQWraRQCLKYDTHSEKIKPQaVIETLWRLTKGDAYVTSDVGQ-----HQMFA 402
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 425 A-----GRPGCYHMEYGFSCMGYEIAGALGIWMADPARDIVCFTGDGTYMMANSELATACMMGAKFTLVITDNRGFGCIN 499
Cdd:PRK07979 403 AlyypfDKPRRWINSGGLGTMGFGLPAALGVKMALPEETVVCVTGDGSIQMNIQELSTALQYELPVLVLNLNNRYLGMVK 482
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*....
gi 2564844288 500 RLQ-MGTGGAefnclldHTVHENPSQIDFVAHAASMGAKAVKAASIAELEEHLAKASDH 557
Cdd:PRK07979 483 QWQdMIYSGR-------HSQSYMQSLPDFVRLAEAYGHVGIQISHPDELESKLSEALEQ 534
|
|
| TPP_enzymes |
cd00568 |
Thiamine pyrophosphate (TPP) enzyme family, TPP-binding module; found in many key metabolic ... |
393-567 |
6.45e-31 |
|
Thiamine pyrophosphate (TPP) enzyme family, TPP-binding module; found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. These enzymes include, among others, the E1 components of the pyruvate, the acetoin and the branched chain alpha-keto acid dehydrogenase complexes.
Pssm-ID: 238318 [Multi-domain] Cd Length: 168 Bit Score: 118.51 E-value: 6.45e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 393 QVVGAVQRSAGPDTVVMCAAGTMPGELHKLWKAGRPGCYHMEYGFSCMGYEIAGALGIWMADPARDIVCFTGDGTYMMAN 472
Cdd:cd00568 1 RVLAALRAALPEDAIVVNDAGNSAYWAYRYLPLRRGRRFLTSTGFGAMGYGLPAAIGAALAAPDRPVVCIAGDGGFMMTG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 473 SELATACMMGAKFTLVITDNRGFGCINRLQMGTGGaefncllDHTVHENPSQIDFVAHAASMGAKAVKAASIAELEEHLA 552
Cdd:cd00568 81 QELATAVRYGLPVIVVVFNNGGYGTIRMHQEAFYG-------GRVSGTDLSNPDFAALAEAYGAKGVRVEDPEDLEAALA 153
|
170
....*....|....*
gi 2564844288 553 KASDHDGVYAIVLDT 567
Cdd:cd00568 154 EALAAGGPALIEVKT 168
|
|
| ilvB |
CHL00099 |
acetohydroxyacid synthase large subunit |
62-571 |
2.20e-30 |
|
acetohydroxyacid synthase large subunit
Pssm-ID: 214363 [Multi-domain] Cd Length: 585 Bit Score: 125.97 E-value: 2.20e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 62 EQTMAHTAIAYSKQLRRDRAMMVTSsiGPGATNMVTACALAYVNRLPVLFVPGDVfahrgpdpvlqqpenfaDGTVTATD 141
Cdd:CHL00099 60 EQGAAHAADGYARSTGKVGVCFATS--GPGATNLVTGIATAQMDSVPLLVITGQV-----------------GRAFIGTD 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 142 TFRPVSRYfdRITRP---EQLLTALPRAMRTMTDPA-------DCGPVTLAFCQDVQAEAYDW----PEAFFAPRVWHRR 207
Cdd:CHL00099 121 AFQEVDIF--GITLPivkHSYVVRDARDISRIVAEAfyiakhgRPGPVLIDIPKDVGLEKFDYyppePGNTIIKILGCRP 198
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 208 AAPPDAGELARVAELLEGAETPVIVAGGGTHYGHATETLKDFAEAHQIPVVETQAGKSALPWDHPLNLGPIGVTGAESAN 287
Cdd:CHL00099 199 IYKPTIKRIEQAAKLILQSSQPLLYVGGGAIISDAHQEITELAELYKIPVTTTLMGKGIFDEDHPLCLGMLGMHGTAYAN 278
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 288 TICAAADVVIGVGTRFQDFTTGSWSLFANPArKLVSLNVQAYDAMKHGAEPL--CCDAKAGLEALSAALgGKTFTAPDAA 365
Cdd:CHL00099 279 FAVSECDLLIALGARFDDRVTGKLDEFACNA-QVIHIDIDPAEIGKNRIPQVaiVGDVKKVLQELLELL-KNSPNLLESE 356
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 366 LKADWFAKVD------PLTdAPEEDANALPtdMQVVGAVQRSAgPDTVVMCAAGTmpgelHKLWKAGRPGCYHMEY---- 435
Cdd:CHL00099 357 QTQAWRERINrwrkeyPLL-IPKPSTSLSP--QEVINEISQLA-PDAYFTTDVGQ-----HQMWAAQFLKCKPRKWlssa 427
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 436 GFSCMGYEIAGALGIWMADPARDIVCFTGDGTYMMANSELATACMMGAKFTLVITDNRGFGCINRLQMGTGGAEFNclld 515
Cdd:CHL00099 428 GLGTMGYGLPAAIGAQIAHPNELVICISGDASFQMNLQELGTIAQYNLPIKIIIINNKWQGMVRQWQQAFYGERYS---- 503
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2564844288 516 htvHENPS--QIDFVAHAASMGAKAVKAASIAELEEHLAKASDHDGVYAI----VLDTDPYP 571
Cdd:CHL00099 504 ---HSNMEegAPDFVKLAEAYGIKGLRIKSRKDLKSSLKEALDYDGPVLIdcqvIEDENCYP 562
|
|
| PRK09107 |
PRK09107 |
acetolactate synthase 3 catalytic subunit; Validated |
6-559 |
9.63e-30 |
|
acetolactate synthase 3 catalytic subunit; Validated
Pssm-ID: 236380 [Multi-domain] Cd Length: 595 Bit Score: 124.05 E-value: 9.63e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 6 LTAAQAMVKYLAAQmtpeGVPYIagcwaiFGH--GNVAGLGEALYHQRDALPTYRGHnEQTMAHTAIAYSKQLRRDRAMM 83
Cdd:PRK09107 11 MTGAEMVVQALKDQ----GVEHI------FGYpgGAVLPIYDEIFQQDDIQHILVRH-EQGAGHAAEGYARSTGKPGVVL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 84 VTSsiGPGATNMVTACALAYVNRLPVLFVPGDVFAHRGPDPVLQQpenfADgTVTATdtfRPVSRYFDRITRPEQLLTAL 163
Cdd:PRK09107 80 VTS--GPGATNAVTPLQDALMDSIPLVCITGQVPTHLIGSDAFQE----CD-TVGIT---RPCTKHNWLVKDVNDLARVI 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 164 PRAMRTMTD--PadcGPVTLAFCQDVQ--AEAYDWPEAF-----FAPRVwhrraaPPDAGELARVAELLEGAETPVIVAG 234
Cdd:PRK09107 150 HEAFHVATSgrP---GPVVVDIPKDVQfaTGTYTPPQKApvhvsYQPKV------KGDAEAITEAVELLANAKRPVIYSG 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 235 GG--THYGHATETLKDFAEAHQIPVVETQAGKSALPWDHPLNLGPIGVTGAESANTICAAADVVIGVGTRFQDFTTGSWS 312
Cdd:PRK09107 221 GGviNSGPEASRLLRELVELTGFPITSTLMGLGAYPASGKNWLGMLGMHGTYEANMAMHDCDVMLCVGARFDDRITGRLD 300
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 313 LFAnPARKLVSLNVQAYDAMK--HGAEPLCCDAKAGLEALSAALGGKTfTAPDAALKADWFAKVD------PLTDAPEED 384
Cdd:PRK09107 301 AFS-PNSKKIHIDIDPSSINKnvRVDVPIIGDVGHVLEDMLRLWKARG-KKPDKEALADWWGQIArwrarnSLAYTPSDD 378
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 385 AnALPTDmqvvgAVQR----SAGPDTVVMCAAGTmpgelHKLWKAG-----RPGCYHMEYGFSCMGYEIAGALGIWMADP 455
Cdd:PRK09107 379 V-IMPQY-----AIQRlyelTKGRDTYITTEVGQ-----HQMWAAQffgfeEPNRWMTSGGLGTMGYGLPAALGVQIAHP 447
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 456 ARDIVCFTGDGTYMMANSELATACMMGAKFTLVITDNRGFGCINRLQMGTGGAEfnclLDHTVHEnpSQIDFVAHAASMG 535
Cdd:PRK09107 448 DALVIDIAGDASIQMCIQEMSTAVQYNLPVKIFILNNQYMGMVRQWQQLLHGNR----LSHSYTE--AMPDFVKLAEAYG 521
|
570 580
....*....|....*....|....
gi 2564844288 536 AKAVKAASIAELEEHLAKASDHDG 559
Cdd:PRK09107 522 AVGIRCEKPGDLDDAIQEMIDVDK 545
|
|
| PRK11269 |
PRK11269 |
glyoxylate carboligase; Provisional |
85-554 |
8.76e-29 |
|
glyoxylate carboligase; Provisional
Pssm-ID: 183066 [Multi-domain] Cd Length: 591 Bit Score: 121.24 E-value: 8.76e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 85 TSsiGPGATNMVTACALAYVNRLPVLFVPGdvfahRGPDPVLQQpENFAdgTVTATDTFRPVSRYFDRITRPEQLLTALP 164
Cdd:PRK11269 75 TS--GPAGTDMITGLYSASADSIPILCITG-----QAPRARLHK-EDFQ--AVDIESIAKPVTKWAVTVREPALVPRVFQ 144
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 165 RAMRTMTD--PadcGPVTLAFCQDVQAEAYDWPEAFFAPRVWHRRAAPPDAGElaRVAELLEGAETPVIVAGGGTHYGHA 242
Cdd:PRK11269 145 QAFHLMRSgrP---GPVLIDLPFDVQVAEIEFDPDTYEPLPVYKPAATRAQIE--KALEMLNAAERPLIVAGGGVINADA 219
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 243 TETLKDFAEAHQIPVVETQAGKSALPWDHPLNLGPIGV-TGAESANTICAAADVVIGVGTRFQDFTTGSWSLFANpARKL 321
Cdd:PRK11269 220 SDLLVEFAELTGVPVIPTLMGWGAIPDDHPLMAGMVGLqTSHRYGNATLLASDFVLGIGNRWANRHTGSVEVYTK-GRKF 298
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 322 VSLNVqaydamkhgaEP------------LCCDAKAGLEALSAAL--GGKTFTAPDaalKADWFAKVDPL--TDAPEEDA 385
Cdd:PRK11269 299 VHVDI----------EPtqigrvfgpdlgIVSDAKAALELLVEVAreWKAAGRLPD---RSAWVADCQERkrTLLRKTHF 365
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 386 NALPTDMQ-VVGAVQRSAGPDTVVMCAAGtmpgeLHKLWKAGRPGCYHMEYGFSC-----MGYEIAGALGIWMADPARDI 459
Cdd:PRK11269 366 DNVPIKPQrVYEEMNKAFGRDTCYVSTIG-----LSQIAAAQFLHVYKPRHWINCgqagpLGWTIPAALGVRAADPDRNV 440
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 460 VCFTGDGTYMMANSELATACMMGAKFTLVITDNRGFGCINRLQMGtggaeFNclLDHTVH---ENPSQ-------IDFVA 529
Cdd:PRK11269 441 VALSGDYDFQFLIEELAVGAQFNLPYIHVLVNNAYLGLIRQAQRA-----FD--MDYCVQlafENINSpelngygVDHVK 513
|
490 500
....*....|....*....|....*
gi 2564844288 530 HAASMGAKAVKAASIAELEEHLAKA 554
Cdd:PRK11269 514 VAEGLGCKAIRVFKPEDIAPALEQA 538
|
|
| PLN02470 |
PLN02470 |
acetolactate synthase |
51-582 |
2.41e-28 |
|
acetolactate synthase
Pssm-ID: 215261 [Multi-domain] Cd Length: 585 Bit Score: 119.84 E-value: 2.41e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 51 RDALPTYrghnEQTMAHTAIAYSKQLRRDRAMMVTSsiGPGATNMVTACALAYVNRLPVLFVPGDVfahrgPDPVLqqpe 130
Cdd:PLN02470 53 RNVLCRH----EQGEVFAAEGYAKASGKVGVCIATS--GPGATNLVTGLADALLDSVPLVAITGQV-----PRRMI---- 117
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 131 nfadgtvtATDTFR--PVSRYFDRITRPEQL---LTALPRAMRT---MTDPADCGPVTLAFCQDVQAEAY--DWPEAFFA 200
Cdd:PLN02470 118 --------GTDAFQetPIVEVTRSITKHNYLvmdVEDIPRVIREaffLASSGRPGPVLVDIPKDIQQQLAvpNWNQPMKL 189
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 201 PRVWHRRAAPPDAGELARVAELLEGAETPVIVAGGGTHygHATETLKDFAEAHQIPVVETQAGKSALPWDHPLNLGPIGV 280
Cdd:PLN02470 190 PGYLSRLPKPPEKSQLEQIVRLISESKRPVVYVGGGCL--NSSEELREFVELTGIPVASTLMGLGAFPASDELSLQMLGM 267
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 281 TGAESANTICAAADVVIGVGTRFQDFTTGSWSLFANPArKLVSLNVQAYDAMKHGAE--PLCCDAKAGLEALSAALGGKT 358
Cdd:PLN02470 268 HGTVYANYAVDSADLLLAFGVRFDDRVTGKLEAFASRA-SIVHIDIDPAEIGKNKQPhvSVCADVKLALQGLNKLLEERK 346
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 359 FTAPDAAlkaDWFAKVD------PLTDAPEEDANALPTDMQVVGavQRSAGpDTVVMCAAGTmpgelHKLWKA-----GR 427
Cdd:PLN02470 347 AKRPDFS---AWRAELDeqkekfPLSYPTFGDAIPPQYAIQVLD--ELTDG-NAIISTGVGQ-----HQMWAAqwykyKE 415
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 428 PGCYHMEYGFSCMGYEIAGALGIWMADPARDIVCFTGDGTYMMANSELATACMMGAKFTLVITDNRGFGCINRLQMGTGG 507
Cdd:PLN02470 416 PRRWLTSGGLGAMGFGLPAAIGAAAANPDAIVVDIDGDGSFIMNIQELATIHVENLPVKIMVLNNQHLGMVVQWEDRFYK 495
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 508 AEfnclLDHTVHENPS---QI--DFVAHAASMGAKAVKAASIAELEEHLAKASDHDGVYaiVLDTD-PY-----PSTPHG 576
Cdd:PLN02470 496 AN----RAHTYLGDPDaeaEIfpDFLKFAEGCKIPAARVTRKSDLREAIQKMLDTPGPY--LLDVIvPHqehvlPMIPGG 569
|
....*.
gi 2564844288 577 GTWWEV 582
Cdd:PLN02470 570 GTFKDI 575
|
|
| PRK08611 |
PRK08611 |
pyruvate oxidase; Provisional |
45-554 |
6.21e-26 |
|
pyruvate oxidase; Provisional
Pssm-ID: 181502 [Multi-domain] Cd Length: 576 Bit Score: 112.40 E-value: 6.21e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 45 EALYHQRDALPTYRGHNEQTMAHTAIAYSKQLRRdraMMVTSSI-GPGATNMVTACALAYVNRLPVLFVPGDVfahrgpd 123
Cdd:PRK08611 35 DALRKEQDKIKFIQVRHEEVAALAAAAYAKLTGK---IGVCLSIgGPGAIHLLNGLYDAKMDHVPVLALAGQV------- 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 124 pvlqqpenfaDGTVTATDTFRPV--SRYFD-------RITRPEQLLTALPRAMRT---------MTDPADCgpvtlaFCQ 185
Cdd:PRK08611 105 ----------TSDLLGTDFFQEVnlEKMFEdvavynhQIMSAENLPEIVNQAIRTayekkgvavLTIPDDL------PAQ 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 186 DVQAEAYDWPEAFFAPRVwhrraaPPDAGELARVAELLEGAETPVIVAGGGTHygHATETLKDFAEAHQIPVVETQAGKS 265
Cdd:PRK08611 169 KIKDTTNKTVDTFRPTVP------SPKPKDIKKAAKLINKAKKPVILAGLGAK--HAKEELLAFAEKAKIPIIHTLPAKG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 266 ALPWDHPLNLGPIGVTGAESANTICAAADVVIGVGTRF--QDF---TTGSWSLFANPAR--KLVSLNVQaydamkhgaep 338
Cdd:PRK08611 241 IIPDDHPYSLGNLGKIGTKPAYEAMQEADLLIMVGTNYpyVDYlpkKAKAIQIDTDPANigKRYPVNVG----------- 309
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 339 LCCDAKAGLEALSAALG---GKTFTAPDAALKADWFAKVDplTDAPEEDANALPTdmQVVGAVQRSAGPDTVVMCAAGTM 415
Cdd:PRK08611 310 LVGDAKKALHQLTENIKhveDRRFLEACQENMAKWWKWME--EDENNASTPIKPE--RVMAAIQKIADDDAVLSVDVGTV 385
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 416 pgelhKLWKAGRpgcYHM----EYGFSC----MGYEIAGALGIWMADPARDIVCFTGDGTYMMANSELATACMMGAKFTL 487
Cdd:PRK08611 386 -----TVWSARY---LNLgtnqKFIISSwlgtMGCGLPGAIAAKIAFPDRQAIAICGDGGFSMVMQDFVTAVKYKLPIVV 457
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2564844288 488 VITDNRGFGCINRLQMGTGGAEFNCLLdhtvhenpSQIDFVAHAASMGAKAVKAASIAELEEHLAKA 554
Cdd:PRK08611 458 VVLNNQQLAFIKYEQQAAGELEYAIDL--------SDMDYAKFAEACGGKGYRVEKAEELDPAFEEA 516
|
|
| PRK08327 |
PRK08327 |
thiamine pyrophosphate-requiring protein; |
61-566 |
2.74e-24 |
|
thiamine pyrophosphate-requiring protein;
Pssm-ID: 236243 [Multi-domain] Cd Length: 569 Bit Score: 107.01 E-value: 2.74e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 61 NEQTMAHTAIAYSKQLRRDRAMMVtsSIGPGATNmvTACAL--AYVNRLPVLfvpgdVFAhrGPDPVLQQPEnfadgtVT 138
Cdd:PRK08327 58 HEIVAISMAHGYALVTGKPQAVMV--HVDVGTAN--ALGGVhnAARSRIPVL-----VFA--GRSPYTEEGE------LG 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 139 ATDTF--------------RPVSRYFDRITRPEQLLTALPRAMRTM-TDPAdcGPVTLAFCQDVQAEAYDWPEAFFAPRV 203
Cdd:PRK08327 121 SRNTRihwtqemrdqgglvREYVKWDYEIRRGDQIGEVVARAIQIAmSEPK--GPVYLTLPREVLAEEVPEVKADAGRQM 198
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 204 WHRRAAPPDAGeLARVAELLEGAETPVIVAGGGTHYGHATETLKDFAEAHQIPVVETQAGKSALPWDHPLNLGPigvtga 283
Cdd:PRK08327 199 APAPPAPDPED-IARAAEMLAAAERPVIITWRAGRTAEGFASLRRLAEELAIPVVEYAGEVVNYPSDHPLHLGP------ 271
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 284 eSANTICAAADVVIGVGTRFqdfttgSWS---LFANPARKLVSLNV---QAYDAMKHGAEPLCCDAKAG--LEALSAALg 355
Cdd:PRK08327 272 -DPRADLAEADLVLVVDSDV------PWIpkkIRPDADARVIQIDVdplKSRIPLWGFPCDLCIQADTStaLDQLEERL- 343
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 356 gKTFTAPDAALKADWFAKVDPL---TDAPEEDANALPTDMQVVGA------VQRSAGPDTVVMCAAGTMPGELhklwKAG 426
Cdd:PRK08327 344 -KSLASAERRRARRRRAAVRELrirQEAAKRAEIERLKDRGPITPaylsycLGEVADEYDAIVTEYPFVPRQA----RLN 418
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 427 RPGCYHMEYGFSCMGYEIAGALGIWMADPARDIVCFTGDGTYMMANSE--LATACMMGAKFTLVITDNRGFGCINR---- 500
Cdd:PRK08327 419 KPGSYFGDGSAGGLGWALGAALGAKLATPDRLVIATVGDGSFIFGVPEaaHWVAERYGLPVLVVVFNNGGWLAVKEavle 498
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2564844288 501 -------LQMGT-GGAEFNclldhtvhenpSQIDFVAHAASMGAKAVKAASIAELEEHLAKASDH--DGVYAIVLD 566
Cdd:PRK08327 499 vypegyaARKGTfPGTDFD-----------PRPDFAKIAEAFGGYGERVEDPEELKGALRRALAAvrKGRRSAVLD 563
|
|
| PDC1 |
COG3961 |
TPP-dependent 2-oxoacid decarboxylase, includes indolepyruvate decarboxylase [Carbohydrate ... |
205-570 |
2.25e-23 |
|
TPP-dependent 2-oxoacid decarboxylase, includes indolepyruvate decarboxylase [Carbohydrate transport and metabolism, Coenzyme transport and metabolism, General function prediction only]; TPP-dependent 2-oxoacid decarboxylase, includes indolepyruvate decarboxylase is part of the Pathway/BioSystem: Pyruvate oxidation
Pssm-ID: 443161 [Multi-domain] Cd Length: 545 Bit Score: 104.08 E-value: 2.25e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 205 HRRAAPPDAGELAR----VAELLEGAETPVIVAGGGTHYGHATETLKDFAEAHQIPVVETQAGKSALPWDHPLNLGpiGV 280
Cdd:COG3961 184 PLPPPASDPAALAAavaaAAERLAKAKRPVILAGVEVHRFGLQEELLALAEKTGIPVATTLLGKSVLDESHPQFIG--TY 261
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 281 TGAESANTICAA---ADVVIGVGTRFQDFTTGSWSLFANPARklvSLNVQAYDAM--KHGAEPLccDAKAGLEALSAALG 355
Cdd:COG3961 262 AGAASSPEVREYvenADCVLCLGVVFTDTNTGGFTAQLDPER---TIDIQPDSVRvgGHIYPGV--SLADFLEALAELLK 336
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 356 GKTFTAPDAALKADWFAKV--DPLTdapeedANALPTDMQvvGAVQrsagPDTVVMCAAGT-----MPGELHK------- 421
Cdd:COG3961 337 KRSAPLPAPAPPPPPPPAApdAPLT------QDRLWQRLQ--AFLD----PGDIVVADTGTslfgaADLRLPEgatfiaq 404
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 422 -LWKAgrpgcyhmeygfscMGYEIAGALGIWMADPARDIVCFTGDGTYMMANSELATACMMGAKFTLVITDNRGFGcINR 500
Cdd:COG3961 405 pLWGS--------------IGYTLPAALGAALAAPDRRVILLVGDGAFQLTAQELSTMLRYGLKPIIFVLNNDGYT-IER 469
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2564844288 501 LQMGTGGAeFNclldhtvheNPSQIDFVAHAASMGAK---AVKAASIAELEEHLAKA-SDHDGVYAIVLDTDPY 570
Cdd:COG3961 470 AIHGPDGP-YN---------DIANWDYAKLPEAFGGGnalGFRVTTEGELEEALAAAeANTDRLTLIEVVLDKM 533
|
|
| TPP_ALS |
cd02010 |
Thiamine pyrophosphate (TPP) family, Acetolactate synthase (ALS) subfamily, TPP-binding module; ... |
393-568 |
4.92e-22 |
|
Thiamine pyrophosphate (TPP) family, Acetolactate synthase (ALS) subfamily, TPP-binding module; composed of proteins similar to Klebsiella pneumoniae ALS, a catabolic enzyme required for butanediol fermentation. ALS catalyzes the conversion of 2 molecules of pyruvate to acetolactate and carbon dioxide. ALS does not contain FAD, and requires TPP and a divalent metal cation for activity.
Pssm-ID: 238968 [Multi-domain] Cd Length: 177 Bit Score: 93.51 E-value: 4.92e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 393 QVVGAVQRSAGPDTVVMCAAGTmpgelHKLW-----KAGRPGCYHMEYGFSCMGYEIAGALGIWMADPARDIVCFTGDGT 467
Cdd:cd02010 3 RIVHDLRAVMGDDDIVLLDVGA-----HKIWmaryyRTYAPNTCLISNGLATMGVALPGAIGAKLVYPDRKVVAVSGDGG 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 468 YMMANSELATACMMGAKFTLVITDNRGFGCINRLQMGTGGAEFNCLLDhtvheNPsqiDFVAHAASMGAKAVKAASIAEL 547
Cdd:cd02010 78 FMMNSQELETAVRLKIPLVVLIWNDNGYGLIKWKQEKEYGRDSGVDFG-----NP---DFVKYAESFGAKGYRIESADDL 149
|
170 180
....*....|....*....|.
gi 2564844288 548 EEHLAKASDHDGVYAIVLDTD 568
Cdd:cd02010 150 LPVLERALAADGVHVIDCPVD 170
|
|
| TPP_PYR_POX_like |
cd07035 |
Pyrimidine (PYR) binding domain of POX and related proteins; Thiamine pyrophosphate (TPP ... |
10-183 |
5.22e-22 |
|
Pyrimidine (PYR) binding domain of POX and related proteins; Thiamine pyrophosphate (TPP family), pyrimidine (PYR) binding domain of pyruvate oxidase (POX) and related protiens subfamily. The PYR domain is found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. TPP binds in the cleft formed by a PYR domain and a PP domain. The PYR domain, binds the aminopyrimidine ring of TPP, the PP domain binds the diphosphate residue. A polar interaction between the conserved glutamate of the PYR domain and the N1' of the TPP aminopyrimidine ring is shared by most TPP-dependent enzymes, and participates in the activation of TPP. For glyoxylate carboligase, which belongs to this subfamily, but lacks this conserved glutamate, the rate of the initial TPP activation step is reduced but the ensuing steps of the enzymic reaction proceed efficiently. The PYR and PP domains have a common fold, but do not share strong sequence conservation. The PP domain is not included in this sub-family. Most TPP-dependent enzymes have the PYR and PP domains on the same subunit although these domains can be alternatively arranged in the primary structure. TPP-dependent enzymes are multisubunit proteins, the smallest catalytic unit being a dimer-of-active sites, for many the active sites lie between PP and PYR domains on different subunits. POX decarboxylates pyruvate, producing hydrogen peroxide and the energy-storage metabolite acetylphosphate. This subfamily includes pyruvate decarboxylase (PDC) and indolepyruvate decarboxylase (IPDC). PDC catalyzes the conversion of pyruvate to acetaldehyde and CO2 in alcoholic fermentation. IPDC plays a role in the indole-3-pyruvic acid (IPA) pathway in plants and various plant-associated bacteria, it catalyzes the decarboxylation of IPA to IAA. This subfamily also includes the large catalytic subunit of acetohydroxyacid synthase (AHAS). AHAS catalyzes the condensation of two molecules of pyruvate to give the acetohydroxyacid, 2-acetolactate, a precursor of the branched chain amino acids, valine and leucine. AHAS also catalyzes the condensation of pyruvate and 2-ketobutyrate to form 2-aceto-2-hydroxybutyrate in isoleucine biosynthesis. Methanococcus jannaschii sulfopyruvate decarboxylase (MjComDE) and phosphonopyruvate decarboxylase (PpyrDc) also belong to this subfamily. PpyrDc is a homotrimeric enzyme having the PP and PYR domains tandemly arranged on the same subunit. It functions in the biosynthesis of C-P compounds such as bialaphos tripeptide in Streptomyces hygroscopicus. MjComDE is a dodecamer having the PYR and PP domains on different subunits, it has six alpha (PYR/ComD) subunits and six beta (PP/ComE) subunits. MjComDE catalyzes the decarboxylation of sulfopyruvic acid to sulfoacetaldehyde in the coenzyme M pathway.
Pssm-ID: 132918 [Multi-domain] Cd Length: 155 Bit Score: 92.59 E-value: 5.22e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 10 QAMVKYLAAQmtpeGVPYIAGcwaIFGHGNVAgLGEALYHqrDALPTYRGHNEQTMAHTAIAYSKQlrRDRAMMVTSSIG 89
Cdd:cd07035 1 DALVEALKAE----GVDHVFG---VPGGAILP-LLDALAR--SGIRYILVRHEQGAVGMADGYARA--TGKPGVVLVTSG 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 90 PGATNMVTACALAYVNRLPVLFVPGDVFAHRGPDPVLQqpenfadgTVTATDTFRPVSRYFDRITRPEQLLTALPRAMRT 169
Cdd:cd07035 69 PGLTNAVTGLANAYLDSIPLLVITGQRPTAGEGRGAFQ--------EIDQVALFRPITKWAYRVTSPEEIPEALRRAFRI 140
|
170
....*....|....
gi 2564844288 170 MTDPAdCGPVTLAF 183
Cdd:cd07035 141 ALSGR-PGPVALDL 153
|
|
| TPP_enzyme_N |
pfam02776 |
Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; |
8-195 |
1.27e-21 |
|
Thiamine pyrophosphate enzyme, N-terminal TPP binding domain;
Pssm-ID: 460690 [Multi-domain] Cd Length: 169 Bit Score: 91.91 E-value: 1.27e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 8 AAQAMVKYLAAqmtpEGVPYIAGcwaIFGHGNVaGLGEALYhQRDALPTYRGHNEQTMAHTAIAYSKqlRRDRAMMVTSS 87
Cdd:pfam02776 1 GAEALADVLKA----LGVDTVFG---VPGGHIL-PLLDALA-KSPGIRYVLTRHEQGAAFAADGYAR--ATGKPGVVLVT 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 88 IGPGATNMVTACALAYVNRLPVLFVPGDVFAHRGPDPVLQQPENFAdgtvtatDTFRPVSRYFDRITRPEQLLTALPRAM 167
Cdd:pfam02776 70 SGPGATNALTGLANAYVDSVPLLVISGQRPRSLVGRGALQQELDQL-------ALFRPVTKWAVRVTSADEIPEVLRRAF 142
|
170 180
....*....|....*....|....*...
gi 2564844288 168 RTMTDPaDCGPVTLAFCQDVQAEAYDWP 195
Cdd:pfam02776 143 RAALSG-RPGPVYLEIPLDVLLEEVDED 169
|
|
| PRK09124 |
PRK09124 |
ubiquinone-dependent pyruvate dehydrogenase; |
143-559 |
4.35e-21 |
|
ubiquinone-dependent pyruvate dehydrogenase;
Pssm-ID: 181661 [Multi-domain] Cd Length: 574 Bit Score: 97.37 E-value: 4.35e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 143 FRPVSRYFDRITRPEQLLTALPRAMRTMTDPADCGPVTLAfcQDVQ-AEAydwPEAffAPRVWHRRAAP---PDAGELAR 218
Cdd:PRK09124 121 FRECSHYCELVSNPEQLPRVLAIAMRKAILNRGVAVVVLP--GDVAlKPA---PER--ATPHWYHAPQPvvtPAEEELRK 193
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 219 VAELLEGAETPVIVAGGGTHYGHAtETLKdFAEAHQIPVVETQAGKSALPWDHPLNLGPIGVTGAESANTICAAADVVIG 298
Cdd:PRK09124 194 LAALLNGSSNITLLCGSGCAGAHD-ELVA-LAETLKAPIVHALRGKEHVEYDNPYDVGMTGLIGFSSGYHAMMNCDTLLM 271
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 299 VGTRF---QDFTTGswslfANPARklVSLNVQAYDAMKHGAEPLCCDAKAGLEALSAALGGKTFTA-PDAALK--ADWFA 372
Cdd:PRK09124 272 LGTDFpyrQFYPTD-----AKIIQ--IDINPGSLGRRSPVDLGLVGDVKATLAALLPLLEEKTDRKfLDKALEhyRKARK 344
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 373 KVDPLTDApeeDANALPTDMQ-VVGAVQRSAGPDTVVMCAAGT----------MPGE--LHKLWKAGRpgcyhmeygfsc 439
Cdd:PRK09124 345 GLDDLAVP---SDGGKPIHPQyLARQISEFAADDAIFTCDVGTptvwaarylkMNGKrrLLGSFNHGS------------ 409
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 440 MGYEIAGALGIWMADPARDIVCFTGDGTYMMANSELATACMMGAKFTLVITDNRGFGCINrLQMGTGGAefncLLDHTVH 519
Cdd:PRK09124 410 MANAMPQALGAQAAHPGRQVVALSGDGGFSMLMGDFLSLVQLKLPVKIVVFNNSVLGFVA-MEMKAGGY----LTDGTDL 484
|
410 420 430 440
....*....|....*....|....*....|....*....|
gi 2564844288 520 ENPsqiDFVAHAASMGAKAVKAASIAELEEHLAKASDHDG 559
Cdd:PRK09124 485 HNP---DFAAIAEACGITGIRVEKASELDGALQRAFAHDG 521
|
|
| PRK06457 |
PRK06457 |
pyruvate dehydrogenase; Provisional |
61-574 |
7.08e-21 |
|
pyruvate dehydrogenase; Provisional
Pssm-ID: 180570 [Multi-domain] Cd Length: 549 Bit Score: 96.44 E-value: 7.08e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 61 NEQTMAHTAIAYSKQLRRDRAMMVTSsiGPGATNMVTACALAYVNRLPVLFVPG----DVFAHrgpdpvlqqpENFADgt 136
Cdd:PRK06457 47 HEEGAALAASVEAKITGKPSACMGTS--GPGSIHLLNGLYDAKMDHAPVIALTGqvesDMIGH----------DYFQE-- 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 137 VTATDTFRPVSRYFDRITRPEQLLTALPRAMRTMTDPADCGPVTLAFcqDVQAEAYDWPEAFFAPRVwhRRAAPPDageL 216
Cdd:PRK06457 113 VNLTKLFDDVAVFNQILINPENAEYIIRRAIREAISKRGVAHINLPV--DILRKSSEYKGSKNTEVG--KVKYSID---F 185
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 217 ARVAELLEGAETPVIVAGGGTHyGHATETLKdFAEAHQIPVVETQAGKSALPWDHPLNLGPIGVTGAESANTICAAADVV 296
Cdd:PRK06457 186 SRAKELIKESEKPVLLIGGGTR-GLGKEINR-FAEKIGAPIIYTLNGKGILPDLDPKVMGGIGLLGTKPSIEAMDKADLL 263
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 297 IGVGTRFqdfttgSWSLFANPARKLVSLNVQAYDAMKHGAEPLCCDAKAGlEALSAALGGKT--FTAPDAALKADWFAKV 374
Cdd:PRK06457 264 IMLGTSF------PYVNFLNKSAKVIQVDIDNSNIGKRLDVDLSYPIPVA-EFLNIDIEEKSdkFYEELKGKKEDWLDSI 336
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 375 DPLtdapEEDANALPTDMQVVGAVQRSAGPDTVVMCAAG--TMPGELHklWKAGRPGCYHMEYGFSCMGYEIAGALGIWM 452
Cdd:PRK06457 337 SKQ----ENSLDKPMKPQRVAYIVSQKCKKDAVIVTDTGnvTMWTARH--FRASGEQTFIFSAWLGSMGIGVPGSVGASF 410
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 453 A-DPARDIVCFTGDGTYMMANSELATACMMGAKFTLVITDNRGFGCINRLQMGTGGAEFNCLLdhtvhENPsqiDFVAHA 531
Cdd:PRK06457 411 AvENKRQVISFVGDGGFTMTMMELITAKKYDLPVKIIIYNNSKLGMIKFEQEVMGYPEWGVDL-----YNP---DFTKIA 482
|
490 500 510 520
....*....|....*....|....*....|....*....|....*
gi 2564844288 532 ASMGAKAVKAASIAELEEHLAKASDHDG--VYAIVLDTDPYPSTP 574
Cdd:PRK06457 483 ESIGFKGFRLEEPKEAEEIIEEFLNTKGpaVLDAIVDPNERPMPP 527
|
|
| TPP_BFDC |
cd02002 |
Thiamine pyrophosphate (TPP) family, BFDC subfamily, TPP-binding module; composed of proteins ... |
394-567 |
9.03e-20 |
|
Thiamine pyrophosphate (TPP) family, BFDC subfamily, TPP-binding module; composed of proteins similar to Pseudomonas putida benzoylformate decarboxylase (BFDC). P. putida BFDC plays a role in the mandelate pathway, catalyzing the conversion of benzoylformate to benzaldehyde and carbon dioxide. This enzyme is dependent on TPP and a divalent metal cation as cofactors.
Pssm-ID: 238960 [Multi-domain] Cd Length: 178 Bit Score: 86.88 E-value: 9.03e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 394 VVGAVQRSAGPDTVVMCAAGTMPGELHKLWKAGRPGCYHMEYGFScMGYEIAGALGIWMADPARDIVCFTGDGTYMMANS 473
Cdd:cd02002 6 LAAALAAALPEDAIIVDEAVTNGLPLRDQLPLTRPGSYFTLRGGG-LGWGLPAAVGAALANPDRKVVAIIGDGSFMYTIQ 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 474 ELATACMMGAKFTLVITDNRGFGCINR--LQMGTGGAEFNCLLDHTVHeNPSqIDFVAHAASMGAKAVKAASIAELEEHL 551
Cdd:cd02002 85 ALWTAARYGLPVTVVILNNRGYGALRSflKRVGPEGPGENAPDGLDLL-DPG-IDFAAIAKAFGVEAERVETPEELDEAL 162
|
170
....*....|....*.
gi 2564844288 552 AKASDHDGVYAIVLDT 567
Cdd:cd02002 163 REALAEGGPALIEVVV 178
|
|
| PRK08617 |
PRK08617 |
acetolactate synthase AlsS; |
83-566 |
2.53e-18 |
|
acetolactate synthase AlsS;
Pssm-ID: 236312 [Multi-domain] Cd Length: 552 Bit Score: 88.37 E-value: 2.53e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 83 MVTSsiGPGATNMVTACALAYVNRLPVLFVPGDVfahRGPDpVLQQpenfadgTVTATDT---FRPVSRYFDRITRPEQL 159
Cdd:PRK08617 72 LVTS--GPGVSNLATGLVTATAEGDPVVAIGGQV---KRAD-RLKR-------THQSMDNvalFRPITKYSAEVQDPDNL 138
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 160 LTALPRAMRTMTDPADcGPVTLAFCQDV-----QAEAYDWPEAffaPRVwhrraAPPDAGELARVAELLEGAETPVIVAG 234
Cdd:PRK08617 139 SEVLANAFRAAESGRP-GAAFVSLPQDVvdapvTSKAIAPLSK---PKL-----GPASPEDINYLAELIKNAKLPVLLLG 209
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 235 GGTHYGHATETLKDFAEAHQIPVVETQAGKSALPWDHPLN-LGPIGVTGAESANTICAAADVVIGVGTRFQDFTTGSWSl 313
Cdd:PRK08617 210 MRASSPEVTAAIRRLLERTNLPVVETFQAAGVISRELEDHfFGRVGLFRNQPGDELLKKADLVITIGYDPIEYEPRNWN- 288
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 314 fANPARKLVSLNV-QA-YDAMKHGAEPLCCDAKAGLEALSAALGGKTFTAPDAALKADWFAKVDPLTDAPEEDANALPTD 391
Cdd:PRK08617 289 -SEGDATIIHIDVlPAeIDNYYQPERELIGDIAATLDLLAEKLDGLSLSPQSLEILEELRAQLEELAERPARLEEGAVHP 367
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 392 MQVVGAVQRSAGPDTVVMCAAGTmpgelHKLWKAGRPGCY---HMEY--GFSCMGYEIAGALGIWMADPARDIVCFTGDG 466
Cdd:PRK08617 368 LRIIRALQDIVTDDTTVTVDVGS-----HYIWMARYFRSYeprHLLFsnGMQTLGVALPWAIAAALVRPGKKVVSVSGDG 442
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 467 TYMMANSELATACMMGAKFTLVITDNRGFGCINRLQMG----TGGAEFnclldhtvhenpSQIDFVAHAASMGAKAVKAA 542
Cdd:PRK08617 443 GFLFSAMELETAVRLKLNIVHIIWNDGHYNMVEFQEEMkygrSSGVDF------------GPVDFVKYAESFGAKGLRVT 510
|
490 500
....*....|....*....|....*.
gi 2564844288 543 SIAELEEHLAKASDHDG--VYAIVLD 566
Cdd:PRK08617 511 SPDELEPVLREALATDGpvVIDIPVD 536
|
|
| TPP_AHAS |
cd02015 |
Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding ... |
393-563 |
1.79e-17 |
|
Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the acetohydroxyacid, 2-acetolactate. 2-Acetolactate is the precursor of the branched chain amino acids, valine and leucine. AHAS also catalyzes the condensation of pyruvate and 2-ketobutyrate to form 2-aceto-2-hydroxybutyrate in isoleucine biosynthesis. In addition to requiring TPP and a divalent metal ion as cofactors, AHAS requires FAD.
Pssm-ID: 238973 [Multi-domain] Cd Length: 186 Bit Score: 80.62 E-value: 1.79e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 393 QVVGAVQRSAGPDTVVMCAAGTmpgelHKLWKA-----GRPGCYHMEYGFSCMGYEIAGALGIWMADPARDIVCFTGDGT 467
Cdd:cd02015 5 EVIKELSELTPGDAIVTTDVGQ-----HQMWAAqyyrfKKPRSWLTSGGLGTMGFGLPAAIGAKVARPDKTVICIDGDGS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 468 YMMANSELATACMMGAKFTLVITDNRGFGCINRLQMgtggAEFNCLLDHTvhENPSQIDFVAHAASMGAKAVKAASIAEL 547
Cdd:cd02015 80 FQMNIQELATAAQYNLPVKIVILNNGSLGMVRQWQE----LFYEGRYSHT--TLDSNPDFVKLAEAYGIKGLRVEKPEEL 153
|
170
....*....|....*.
gi 2564844288 548 EEHLAKASDHDGVYAI 563
Cdd:cd02015 154 EAALKEALASDGPVLL 169
|
|
| TPP_POX |
cd02014 |
Thiamine pyrophosphate (TPP) family, Pyruvate oxidase (POX) subfamily, TPP-binding module; ... |
393-569 |
3.71e-15 |
|
Thiamine pyrophosphate (TPP) family, Pyruvate oxidase (POX) subfamily, TPP-binding module; composed of proteins similar to Lactobacillus plantarum POX, which plays a key role in controlling acetate production under aerobic conditions. POX decarboxylates pyruvate, producing hydrogen peroxide and the energy-storage metabolite acetylphosphate. It requires FAD in addition to TPP and a divalent cation as cofactors.
Pssm-ID: 238972 [Multi-domain] Cd Length: 178 Bit Score: 73.72 E-value: 3.71e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 393 QVVGAVQRSAGPDTVVMCAAGTmpgelHKLW-----KAGRPGCYHMEYGFSCMGYEIAGALGIWMADPARDIVCFTGDGT 467
Cdd:cd02014 6 RVAAELNKRAPDDAIFTIDVGN-----VTVWaarhlRMNGKQRFILSGLLATMGNGLPGAIAAKLAYPDRQVIALSGDGG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 468 YMMANSELATACMMGAKFTLVITDNRGFGCINRLQMGTGGAEFNCLLDHtvhenpsqIDFVAHAASMGAKAVKAASIAEL 547
Cdd:cd02014 81 FAMLMGDLITAVKYNLPVIVVVFNNSDLGFIKWEQEVMGQPEFGVDLPN--------PDFAKIAEAMGIKGIRVEDPDEL 152
|
170 180
....*....|....*....|....
gi 2564844288 548 EEHLAKASDHDGvyAIVLD--TDP 569
Cdd:cd02014 153 EAALDEALAADG--PVVIDvvTDP 174
|
|
| PRK09259 |
PRK09259 |
putative oxalyl-CoA decarboxylase; Validated |
89-576 |
9.38e-14 |
|
putative oxalyl-CoA decarboxylase; Validated
Pssm-ID: 236433 [Multi-domain] Cd Length: 569 Bit Score: 74.25 E-value: 9.38e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 89 GPGATNMVTACALAYVNRLPVLFVPGD-----VFAHRGPDPVLQQpENFAdgtvtatdtfRPVSRYFDRITRPEQLLTAL 163
Cdd:PRK09259 81 APGFLNGLTALANATTNCFPMIMISGSsereiVDLQQGDYEELDQ-LNAA----------KPFCKAAFRVNRAEDIGIGV 149
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 164 PRAMRTMTD--PadcGPVTLAFCQDVQAEAYDWPEAffAPRVWH-RRAAP-----PDAgeLARVAELLEGAETPVIVAGG 235
Cdd:PRK09259 150 ARAIRTAVSgrP---GGVYLDLPAKVLAQTMDADEA--LTSLVKvVDPAPaqlpaPEA--VDRALDLLKKAKRPLIILGK 222
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 236 GTHYGHATETLKDFAEAHQIPVVETQAGKSALPWDHPLNLGpigvtGAESanTICAAADVVIGVGTRFqdfttgSWSLFA 315
Cdd:PRK09259 223 GAAYAQADEQIREFVEKTGIPFLPMSMAKGLLPDTHPQSAA-----AARS--LALANADVVLLVGARL------NWLLSH 289
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 316 ------NPARKLVSLNVQA--YDAMKHGAEPLCCDAKAGLEALSAALGGKTFTAPdaalkADWFAKVDPLTD------AP 381
Cdd:PRK09259 290 gkgktwGADKKFIQIDIEPqeIDSNRPIAAPVVGDIGSVMQALLAGLKQNTFKAP-----AEWLDALAERKEknaakmAE 364
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 382 EEDANALPTD----MQVVGAVQRsAGPDT-VVMCAAGT---------MPGELHKL----WkaGRPGCyhmeygfsCMGYE 443
Cdd:PRK09259 365 KLSTDTQPMNfynaLGAIRDVLK-ENPDIyLVNEGANTldlarniidMYKPRHRLdcgtW--GVMGI--------GMGYA 433
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 444 IAGALgiwmaDPARDIVCFTGDGTYMMANSELATACMMGAKFTLVITDNRGfgcINRlqmGTGgaefnclLDHTVHENPS 523
Cdd:PRK09259 434 IAAAV-----ETGKPVVAIEGDSAFGFSGMEVETICRYNLPVTVVIFNNGG---IYR---GDD-------VNLSGAGDPS 495
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*....
gi 2564844288 524 QIDFVAHA------ASMGAKAVKAASIAELEEHLAKASDHDGVYAIVLDTDPYPSTPHG 576
Cdd:PRK09259 496 PTVLVHHArydkmmEAFGGVGYNVTTPDELRHALTEAIASGKPTLINVVIDPAAGTESG 554
|
|
| PRK06546 |
PRK06546 |
pyruvate dehydrogenase; Provisional |
143-569 |
6.26e-13 |
|
pyruvate dehydrogenase; Provisional
Pssm-ID: 180614 [Multi-domain] Cd Length: 578 Bit Score: 71.56 E-value: 6.26e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 143 FRPVSRYFDRITRPEQLltalPRAMRTMTDPADCGP--VTLAFCQDV--QAEAYDWPEAFFAPRvwhRRAAPPDAGELAR 218
Cdd:PRK06546 121 FVECSGYCEMVSSAEQA----PRVLHSAIQHAVAGGgvSVVTLPGDIadEPAPEGFAPSVISPR---RPTVVPDPAEVRA 193
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 219 VAELLEGAETPVIVAGGGTHYGHAtETLKdFAEAHQIPVVETQAGKSALPWDHPLNLGPIGVTGAESANTICAAADVVIG 298
Cdd:PRK06546 194 LADAINEAKKVTLFAGAGVRGAHA-EVLA-LAEKIKAPVGHSLRGKEWIQYDNPFDVGMSGLLGYGAAHEAMHEADLLIL 271
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 299 VGTRF--QDF--TTGSWSLFANPA----RKLVSLNVqaydamkHGaeplccDAKAGLEALSAALGGKT---FTapDAALK 367
Cdd:PRK06546 272 LGTDFpyDQFlpDVRTAQVDIDPEhlgrRTRVDLAV-------HG------DVAETIRALLPLVKEKTdrrFL--DRMLK 336
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 368 AD----------WFAKVDPLTDA-PEEDANALptdmqvvgavQRSAGPDTVV-----MC----AAGTMPGELHKLWKAGR 427
Cdd:PRK06546 337 KHarklekvvgaYTRKVEKHTPIhPEYVASIL----------DELAADDAVFtvdtgMCnvwaARYITPNGRRRVIGSFR 406
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 428 PGCyhmeygfscMGYEIAGALGIWMADPARDIVCFTGDGTYMMANSELATACMMGAKFTLVITDNRGFGCInRLQMGTGG 507
Cdd:PRK06546 407 HGS---------MANALPHAIGAQLADPGRQVISMSGDGGLSMLLGELLTVKLYDLPVKVVVFNNSTLGMV-KLEMLVDG 476
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2564844288 508 aefncLLDH-TVHENPsqiDFVAHAASMGAKAVKAASIAELEEHLAKASDHDGVYAIVLDTDP 569
Cdd:PRK06546 477 -----LPDFgTDHPPV---DYAAIAAALGIHAVRVEDPKDVRGALREAFAHPGPALVDVVTDP 531
|
|
| TPP_IOR_alpha |
cd02008 |
Thiamine pyrophosphate (TPP) family, IOR-alpha subfamily, TPP-binding module; composed of ... |
429-566 |
5.56e-10 |
|
Thiamine pyrophosphate (TPP) family, IOR-alpha subfamily, TPP-binding module; composed of proteins similar to indolepyruvate ferredoxin oxidoreductase (IOR) alpha subunit. IOR catalyzes the oxidative decarboxylation of arylpyruvates, such as indolepyruvate or phenylpyruvate, which are generated by the transamination of aromatic amino acids, to the corresponding aryl acetyl-CoA.
Pssm-ID: 238966 [Multi-domain] Cd Length: 178 Bit Score: 58.83 E-value: 5.56e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 429 GCYHMEY--------GFSCMGYEIAGALGIWMADPARDIVCFTGDGTYMMANSE-LATACMMGAKFTLVITDNRGFGcin 499
Cdd:cd02008 34 GCYTLGAlpplnaidTCTCMGASIGVAIGMAKASEDKKVVAVIGDSTFFHSGILgLINAVYNKANITVVILDNRTTA--- 110
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 500 rlqMgTGGaEFNCLLDHTVHENPSQIDFVAHAASMGAKAV---KAASIAELEEHLAKASDHDGVYAIVLD 566
Cdd:cd02008 111 ---M-TGG-QPHPGTGKTLTEPTTVIDIEALVRAIGVKRVvvvDPYDLKAIREELKEALAVPGVSVIIAK 175
|
|
| PLN02573 |
PLN02573 |
pyruvate decarboxylase |
219-495 |
5.71e-10 |
|
pyruvate decarboxylase
Pssm-ID: 215311 [Multi-domain] Cd Length: 578 Bit Score: 62.03 E-value: 5.71e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 219 VAELLEGAETPVIVAGGGTHYGHATETLKDFAEAHQIPVVETQAGKSALPWDHPLNLGPigVTGAESAnTICA----AAD 294
Cdd:PLN02573 217 AAEFLNKAVKPVLVGGPKLRVAKACKAFVELADASGYPVAVMPSAKGLVPEHHPHFIGT--YWGAVST-PFCAeiveSAD 293
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 295 VVIGVGTRFQDFTTGSWSLFANPARKLVslnVQAYDAM-KHGAEPLCCDAKAGLEALSAALGGKTfTAPDaALKADWFAK 373
Cdd:PLN02573 294 AYLFAGPIFNDYSSVGYSLLLKKEKAII---VQPDRVTiGNGPAFGCVLMKDFLEALAKRVKKNT-TAYE-NYKRIFVPE 368
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 374 VDPLTDAPEE--DANALptdmqvVGAVQRSAGPDTVVMCAAGTMPGELHKLWKAgrPGC---YHMEYGfsCMGYEIAGAL 448
Cdd:PLN02573 369 GEPLKSEPGEplRVNVL------FKHIQKMLSGDTAVIAETGDSWFNCQKLKLP--EGCgyeFQMQYG--SIGWSVGATL 438
|
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 2564844288 449 GIWMADPARDIVCFTGDGTYMMANSELATACMMGAKFTLVITDNRGF 495
Cdd:PLN02573 439 GYAQAAPDKRVIACIGDGSFQVTAQDVSTMIRCGQKSIIFLINNGGY 485
|
|
| PRK08273 |
PRK08273 |
thiamine pyrophosphate protein; Provisional |
147-303 |
2.70e-08 |
|
thiamine pyrophosphate protein; Provisional
Pssm-ID: 181344 [Multi-domain] Cd Length: 597 Bit Score: 56.84 E-value: 2.70e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 147 SRYFDRITRPEQLLTALPRAMRTMTdpADCGPVTLAFCQDVQAEAYDWPEAFFAPRV----WHRRAAPPDAGELARVAEL 222
Cdd:PRK08273 127 GAFVQMVTVPEQLRHLVDRAVRTAL--AERTVTAVILPNDVQELEYEPPPHAHGTVHsgvgYTRPRVVPYDEDLRRAAEV 204
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 223 LEGAETPVIVAGGGTHygHATETLKDFAEAHQIPVVETQAGKSALPWDHPLNLGPIGVTGAESANTICAAADVVIGVGTR 302
Cdd:PRK08273 205 LNAGRKVAILVGAGAL--GATDEVIAVAERLGAGVAKALLGKAALPDDLPWVTGSIGLLGTKPSYELMRECDTLLMVGSS 282
|
.
gi 2564844288 303 F 303
Cdd:PRK08273 283 F 283
|
|
| TPP_PYR_POX |
cd07039 |
Pyrimidine (PYR) binding domain of POX; Thiamine pyrophosphate (TPP family), pyrimidine (PYR) ... |
7-169 |
1.28e-07 |
|
Pyrimidine (PYR) binding domain of POX; Thiamine pyrophosphate (TPP family), pyrimidine (PYR) binding domain of pyruvate oxidase (POX) subfamily. The PYR domain is found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. TPP binds in the cleft formed by a PYR domain and a PP domain. The PYR domain, binds the aminopyrimidine ring of TPP, the PP domain binds the diphosphate residue. The PYR and PP domains have a common fold, but do not share strong sequence conservation. The PP domain is not included in this sub-family. Most TPP-dependent enzymes have the PYR and PP domains on the same subunit although these domains can be alternatively arranged in the primary structure. TPP-dependent enzymes are multisubunit proteins, the smallest catalytic unit being a dimer-of-active sites. Lactobacillus plantarum POX is a homotetramer (dimer-of-homodimers), having two active sites per homodimer lying between PYR and PP domains of different subunits. POX decarboxylates pyruvate, producing hydrogen peroxide and the energy-storage metabolite acetylphosphate.
Pssm-ID: 132922 [Multi-domain] Cd Length: 164 Bit Score: 51.40 E-value: 1.28e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 7 TAAQAMVKYLAAQmtpeGVPYIAGcwaIFGHGNvAGLGEALyhQRDALPTYRG--HnEQTMAHTAIAYSKQLRRDRAMMV 84
Cdd:cd07039 1 TVADVIVETLENW----GVKRVYG---IPGDSI-NGLMDAL--RREGKIEFIQvrH-EEAAAFAASAEAKLTGKLGVCLG 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 85 TSsiGPGATNMVTACALAYVNRLPVLFVPGDVFAHR-GPDpvLQQPENFadgtvtaTDTFRPVSRYFDRITRPEQLLTAL 163
Cdd:cd07039 70 SS--GPGAIHLLNGLYDAKRDRAPVLAIAGQVPTDElGTD--YFQEVDL-------LALFKDVAVYNETVTSPEQLPELL 138
|
....*.
gi 2564844288 164 PRAMRT 169
Cdd:cd07039 139 DRAIRT 144
|
|
| PRK07586 |
PRK07586 |
acetolactate synthase large subunit; |
144-565 |
1.85e-07 |
|
acetolactate synthase large subunit;
Pssm-ID: 236063 [Multi-domain] Cd Length: 514 Bit Score: 54.08 E-value: 1.85e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 144 RPVSRYFDRITRPEQLLTALPRAMR-TMTDPAdcGPVTLAFCQDVQAEAYDWPEAffaPRVWHRRAAPPDAgELARVAEL 222
Cdd:PRK07586 120 RPVSGWVRRSESAADVAADAAAAVAaARGAPG--QVATLILPADVAWSEGGPPAP---PPPAPAPAAVDPA-AVEAAAAA 193
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 223 LEGAETPVIVAGGGTHYGHATETLKDFAEAHQI--------PVVETQAGKSA---LPWDhplnlgpigvtgAESANTICA 291
Cdd:PRK07586 194 LRSGEPTVLLLGGRALRERGLAAAARIAAATGArllaetfpARMERGAGRPAverLPYF------------AEQALAQLA 261
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 292 AADVVIGVGTRfqdfttGSWSLFANPARK--LVSLNVQAyDAMKHGAEplccDAKAGLEALSAALGGKTfTAPDAALKAD 369
Cdd:PRK07586 262 GVRHLVLVGAK------APVAFFAYPGKPsrLVPEGCEV-HTLAGPGE----DAAAALEALADALGAKP-AAPPLAAPAR 329
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 370 WFAKVDPLTDApeedanalpTDMQVVGAVQrsagP-DTVVMCAAGTMPGELHKLWKAGRPGCYHMEYGFScMGYEIAGAL 448
Cdd:PRK07586 330 PPLPTGALTPE---------AIAQVIAALL----PeNAIVVDESITSGRGFFPATAGAAPHDWLTLTGGA-IGQGLPLAT 395
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 449 GIWMADPARDIVCFTGDGTYMMANSELATACMMGAKFTLVITDNRGFGCIN----RLQMGTGGAEFNCLLDHtvhENPSq 524
Cdd:PRK07586 396 GAAVACPDRKVLALQGDGSAMYTIQALWTQARENLDVTTVIFANRAYAILRgelaRVGAGNPGPRALDMLDL---DDPD- 471
|
410 420 430 440
....*....|....*....|....*....|....*....|.
gi 2564844288 525 IDFVAHAASMGAKAVKAASIAELEEHLAKASDHDGVYAIVL 565
Cdd:PRK07586 472 LDWVALAEGMGVPARRVTTAEEFADALAAALAEPGPHLIEA 512
|
|
| TPP_BZL_OCoD_HPCL |
cd02004 |
Thiamine pyrophosphate (TPP) family, BZL_OCoD_HPCL subfamily, TPP-binding module; composed of ... |
393-563 |
1.12e-06 |
|
Thiamine pyrophosphate (TPP) family, BZL_OCoD_HPCL subfamily, TPP-binding module; composed of proteins similar to benzaldehyde lyase (BZL), oxalyl-CoA decarboxylase (OCoD) and 2-hydroxyphytanoyl-CoA lyase (2-HPCL). Pseudomonas fluorescens biovar I BZL cleaves the acyloin linkage of benzoin producing 2 molecules of benzaldehyde and enabling the Pseudomonas to grow on benzoin as the sole carbon and energy source. OCoD has a role in the detoxification of oxalate, catalyzing the decarboxylation of oxalyl-CoA to formate. 2-HPCL is a peroxisomal enzyme which plays a role in the alpha-oxidation of 3-methyl-branched fatty acids, catalyzing the cleavage of 2-hydroxy-3-methylacyl-CoA into formyl-CoA and a 2-methyl-branched fatty aldehyde. All these enzymes depend on Mg2+ and TPP for activity.
Pssm-ID: 238962 [Multi-domain] Cd Length: 172 Bit Score: 49.07 E-value: 1.12e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 393 QVVGAVQRsAGPDTVVMCAAG--TMpGELHKLWKAGRPGCY-------HMEYGfscMGYEIAGALgiwmADPARDIVCFT 463
Cdd:cd02004 3 RVLHELQE-ALPDDAIIVSDGgnTM-DWARYILRPRKPRHRldagtfgTLGVG---LGYAIAAAL----ARPDKRVVLVE 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 464 GDGTYMMANSELATACMMGAKFTLVITDNRGFGCINRLQMGTGGaefncLLDHTVHENPSqIDFVAHAASMGAKAVKAAS 543
Cdd:cd02004 74 GDGAFGFSGMELETAVRYNLPIVVVVGNNGGWYQGLDGQQLSYG-----LGLPVTTLLPD-TRYDLVAEAFGGKGELVTT 147
|
170 180
....*....|....*....|
gi 2564844288 544 IAELEEHLAKASDHDGVYAI 563
Cdd:cd02004 148 PEELKPALKRALASGKPALI 167
|
|
| TPP_Xsc_like |
cd02013 |
Thiamine pyrophosphate (TPP) family, Xsc-like subfamily, TPP-binding module; composed of ... |
437-556 |
1.37e-06 |
|
Thiamine pyrophosphate (TPP) family, Xsc-like subfamily, TPP-binding module; composed of proteins similar to Alcaligenes defragrans sulfoacetaldehyde acetyltransferase (Xsc). Xsc plays a key role in the degradation of taurine, catalyzing the desulfonation of 2-sulfoacetaldehyde into sulfite and acetyl phosphate. This enzyme requires TPP and divalent metal ions for activity.
Pssm-ID: 238971 [Multi-domain] Cd Length: 196 Bit Score: 49.05 E-value: 1.37e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 437 FSCMGYEIAGALGIWMADPARDIVCFTGDGTYMMANSELATACMMGAKFTLVITDNRGFGCINRLQMGTGGAEFNClldh 516
Cdd:cd02013 52 FGNCGYALPAIIGAKAAAPDRPVVAIAGDGAWGMSMMEIMTAVRHKLPVTAVVFRNRQWGAEKKNQVDFYNNRFVG---- 127
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 2564844288 517 TVHENPSQIDFvahAASMGAKAVKAASIAELEEHLAKASD 556
Cdd:cd02013 128 TELESESFAKI---AEACGAKGITVDKPEDVGPALQKAIA 164
|
|
| TPP_PpyrDC |
cd03371 |
Thiamine pyrophosphate (TPP) family, PpyrDC subfamily, TPP-binding module; composed of ... |
395-559 |
2.64e-06 |
|
Thiamine pyrophosphate (TPP) family, PpyrDC subfamily, TPP-binding module; composed of proteins similar to phosphonopyruvate decarboxylase (PpyrDC) proteins. PpyrDC is a homotrimeric enzyme which functions in the biosynthesis of C-P compounds such as bialaphos tripeptide in Streptomyces hygroscopicus. These proteins require TPP and divalent metal cation cofactors.
Pssm-ID: 239468 [Multi-domain] Cd Length: 188 Bit Score: 48.08 E-value: 2.64e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 395 VGAVQRSAGPDTVVMCAAGTMPGELHKLwkAGRPGCYHME--YGFSCMGYEIAGALGIWMADPARDIVCFTGDGTYMMAN 472
Cdd:cd03371 5 IEIVLSRAPATAAVVSTTGMTSRELFEL--RDRPGGGHAQdfLTVGSMGHASQIALGIALARPDRKVVCIDGDGAALMHM 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 473 SELAT-ACMMGAKFTLVITDNRGFGcinrlqmGTGGAEfnclldhTVhenPSQIDFVAHAASMG-AKAVKAASIAELEEH 550
Cdd:cd03371 83 GGLATiGGLAPANLIHIVLNNGAHD-------SVGGQP-------TV---SFDVSLPAIAKACGyRAVYEVPSLEELVAA 145
|
....*....
gi 2564844288 551 LAKASDHDG 559
Cdd:cd03371 146 LAKALAADG 154
|
|
| TPP_Gcl |
cd02006 |
Thiamine pyrophosphate (TPP) family, Gcl subfamily, TPP-binding module; composed of proteins ... |
440-554 |
8.65e-06 |
|
Thiamine pyrophosphate (TPP) family, Gcl subfamily, TPP-binding module; composed of proteins similar to Escherichia coli glyoxylate carboligase (Gcl). E. coli glyoxylate carboligase, plays a key role in glyoxylate metabolism where it catalyzes the condensation of two molecules of glyoxylate to give tartronic semialdehyde and carbon dioxide. This enzyme requires TPP, magnesium ion and FAD as cofactors.
Pssm-ID: 238964 [Multi-domain] Cd Length: 202 Bit Score: 46.89 E-value: 8.65e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 440 MGYEIAGALGIWMADPARDIVCFTGDGTYMMANSELATACMMGAKFTLVITDNRGFGCINRLQMGtggaeFNclLDHTVH 519
Cdd:cd02006 59 LGWTVPAALGVAAADPDRQVVALSGDYDFQFMIEELAVGAQHRIPYIHVLVNNAYLGLIRQAQRA-----FD--MDYQVN 131
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 2564844288 520 ----------ENPSQIDFVAHAASMGAKAVKAASIAELEEHLAKA 554
Cdd:cd02006 132 lafeninsseLGGYGVDHVKVAEGLGCKAIRVTKPEELAAAFEQA 176
|
|
| TPP_ComE_PpyrDC |
cd02001 |
Thiamine pyrophosphate (TPP) family, ComE and PpyrDC subfamily, TPP-binding module; composed ... |
427-570 |
5.71e-05 |
|
Thiamine pyrophosphate (TPP) family, ComE and PpyrDC subfamily, TPP-binding module; composed of proteins similar to sulfopyruvate decarboxylase beta subunit (ComE) and phosphonopyruvate decarboxylase (Ppyr decarboxylase). Methanococcus jannaschii sulfopyruvate decarboxylase (ComDE) is a dodecamer of six alpha (D) subunits and six (E) beta subunits which, catalyzes the decarboxylation of sulfopyruvic acid to sulfoacetaldehyde in the coenzyme M pathway. Ppyr decarboxylase is a homotrimeric enzyme which functions in the biosynthesis of C-P compounds such as bialaphos tripeptide in Streptomyces hygroscopicus. Ppyr decarboxylase and ComDE require TPP and divalent metal cation cofactors.
Pssm-ID: 238959 [Multi-domain] Cd Length: 157 Bit Score: 43.63 E-value: 5.71e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 427 RPGCYHMeygFSCMGYEIAGALGIWMADPaRDIVCFTGDGTYMMANSELATACMMGAK-FTLVITDNRGFGcinrlqmGT 505
Cdd:cd02001 34 RDGHFYM---LGSMGLAGSIGLGLALGLS-RKVIVVDGDGSLLMNPGVLLTAGEFTPLnLILVVLDNRAYG-------ST 102
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2564844288 506 GGAEfnclldhtvhENPSQIDFVAHAASMGAKAVKAASIAELEEHLAKASDHDGVYAIVLDTDPY 570
Cdd:cd02001 103 GGQP----------TPSSNVNLEAWAAACGYLVLSAPLLGGLGSEFAGLLATTGPTLLHAPIAPG 157
|
|
| PRK06163 |
PRK06163 |
hypothetical protein; Provisional |
420-571 |
1.08e-04 |
|
hypothetical protein; Provisional
Pssm-ID: 235721 [Multi-domain] Cd Length: 202 Bit Score: 43.67 E-value: 1.08e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 420 HKLWKAG-RPGCYHMeygFSCMGYEIAGALGIWMADPARDIVCFTGDGTYMMANSELAT-ACMMGAKFTLVITDNrGFGC 497
Cdd:PRK06163 41 FDLWAAGqRPQNFYM---LGSMGLAFPIALGVALAQPKRRVIALEGDGSLLMQLGALGTiAALAPKNLTIIVMDN-GVYQ 116
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2564844288 498 InrlqmgTGGAEfnCLLDHTVhenpsqiDFVAHAASMG-AKAVKAASIAELEEHLAKASDHDGVYAIVLDTDPYP 571
Cdd:PRK06163 117 I------TGGQP--TLTSQTV-------DVVAIARGAGlENSHWAADEAHFEALVDQALSGPGPSFIAVRIDDKP 176
|
|
| PRK12474 |
PRK12474 |
hypothetical protein; Provisional |
363-563 |
1.72e-04 |
|
hypothetical protein; Provisional
Pssm-ID: 139002 [Multi-domain] Cd Length: 518 Bit Score: 44.48 E-value: 1.72e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 363 DAALKADWFAkvDPLtDAPEEDAN-------ALPTDMQVVGAVQRSAG---PDTVVMC-AAGTMPGELHKLWKAGRPGCY 431
Cdd:PRK12474 307 DLAQALQDLA--DAV-DAPAEPAArtplalpALPKGALNSLGVAQLIAhrtPDQAIYAdEALTSGLFFDMSYDRARPHTH 383
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 432 HMEYGFScMGYEIAGALGIWMADPARDIVCFTGDGTYMMANSELATACMMGAKFTLVITDNRGFGCIN----RLQMGTGG 507
Cdd:PRK12474 384 LPLTGGS-IGQGLPLAAGAAVAAPDRKVVCPQGDGGAAYTMQALWTMARENLDVTVVIFANRSYAILNgelqRVGAQGAG 462
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 2564844288 508 AEFNCLLDhtvHENPsQIDFVAHAASMGAKAVKAASIAELEEHLAKASDHDGVYAI 563
Cdd:PRK12474 463 RNALSMLD---LHNP-ELNWMKIAEGLGVEASRATTAEEFSAQYAAAMAQRGPRLI 514
|
|
| TPP_ComE |
cd03372 |
Thiamine pyrophosphate (TPP) family, ComE subfamily, TPP-binding module; composed of proteins ... |
422-572 |
1.92e-04 |
|
Thiamine pyrophosphate (TPP) family, ComE subfamily, TPP-binding module; composed of proteins similar to Methanococcus jannaschii sulfopyruvate decarboxylase beta subunit (ComE). M. jannaschii sulfopyruvate decarboxylase (ComDE) is a dodecamer of six alpha (D) subunits and six (E) beta subunits, which catalyzes the decarboxylation of sulfopyruvic acid to sulfoacetaldehyde in the coenzyme M pathway. ComDE requires TPP and divalent metal cation cofactors.
Pssm-ID: 239469 [Multi-domain] Cd Length: 179 Bit Score: 42.66 E-value: 1.92e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 422 LWKAG-RPGCYHMeygFSCMGYEIAGALGIWMADPARDIVcFTGDGTYMMANSELATACMMGAK-FTLVITDNRGFGcin 499
Cdd:cd03372 28 LYAAGdRPLNFYM---LGSMGLASSIGLGLALAQPRKVIV-IDGDGSLLMNLGALATIAAEKPKnLIIVVLDNGAYG--- 100
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2564844288 500 rlqmGTGGAEfncllDHTvhenPSQIDFVAHAASMG-AKAVKAASIAELEEhlAKASDHDGVYAIVLDTDPYPS 572
Cdd:cd03372 101 ----STGNQP-----THA----GKKTDLEAVAKACGlDNVATVASEEAFEK--AVEQALDGPSFIHVKIKPGNT 159
|
|
| TPP_PDC_IPDC |
cd02005 |
Thiamine pyrophosphate (TPP) family, PDC_IPDC subfamily, TPP-binding module; composed of ... |
440-564 |
3.03e-04 |
|
Thiamine pyrophosphate (TPP) family, PDC_IPDC subfamily, TPP-binding module; composed of proteins similar to pyruvate decarboxylase (PDC) and indolepyruvate decarboxylase (IPDC). PDC, a key enzyme in alcoholic fermentation, catalyzes the conversion of pyruvate to acetaldehyde and CO2. It is able to utilize other 2-oxo acids as substrates. In plants and various plant-associated bacteria, IPDC plays a role in the indole-3-pyruvic acid (IPA) pathway, a tryptophan-dependent biosynthetic route to indole-3-acetaldehyde (IAA). IPDC catalyzes the decarboxylation of IPA to IAA. Both PDC and IPDC depend on TPP and Mg2+ as cofactors.
Pssm-ID: 238963 [Multi-domain] Cd Length: 183 Bit Score: 42.14 E-value: 3.03e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 440 MGYEIAGALGIWMADPARDIVCFTGDGTYMMANSELATACMMGAKFTLVITDNRGFGcINRLQMGtGGAEFNCLLDHTVH 519
Cdd:cd02005 52 IGYSVPAALGAALAAPDRRVILLVGDGSFQMTVQELSTMIRYGLNPIIFLINNDGYT-IERAIHG-PEASYNDIANWNYT 129
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 2564844288 520 ENPSqidfvAHAASMGAKAVKAASIAELEEHLAKASDHDGVYAIV 564
Cdd:cd02005 130 KLPE-----VFGGGGGGLSFRVKTEGELDEALKDALFNRDKLSLI 169
|
|
| TPP_SHCHC_synthase |
cd02009 |
Thiamine pyrophosphate (TPP) family, SHCHC synthase subfamily, TPP-binding module; composed of ... |
444-559 |
1.14e-03 |
|
Thiamine pyrophosphate (TPP) family, SHCHC synthase subfamily, TPP-binding module; composed of proteins similar to Escherichia coli 2-succinyl-6-hydroxyl-2,4-cyclohexadiene-1-carboxylic acid (SHCHC) synthase (also called MenD). SHCHC synthase plays a key role in the menaquinone biosynthetic pathway, converting isochorismate and 2-oxoglutarate to SHCHC, pyruvate and carbon dioxide. The enzyme requires TPP and a divalent metal cation for activity.
Pssm-ID: 238967 [Multi-domain] Cd Length: 175 Bit Score: 40.27 E-value: 1.14e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564844288 444 IAGALGIWMADPARdIVCFTGDGTYMM-ANSeLATACMMGAKFTLVITDNRGFGCINRLQMGTGGAEFNclldhTVHENP 522
Cdd:cd02009 57 LSTALGIALATDKP-TVLLTGDLSFLHdLNG-LLLGKQEPLNLTIVVINNNGGGIFSLLPQASFEDEFE-----RLFGTP 129
|
90 100 110
....*....|....*....|....*....|....*...
gi 2564844288 523 SQIDFvAHAASM-GAKAVKAASIAELEEHLAKASDHDG 559
Cdd:cd02009 130 QGLDF-EHLAKAyGLEYRRVSSLDELEQALESALAQDG 166
|
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| |
