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Conserved domains on  [gi|2564918461|ref|WP_306120373|]
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MULTISPECIES: SdrD B-like domain-containing protein [unclassified Roseitalea]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ClfA COG4932
Clumping factor A-related surface protein, MSCRAMM (microbial surface components recognizing ...
 187-339 4.73e-08

Clumping factor A-related surface protein, MSCRAMM (microbial surface components recognizing adhesive matrix molecules) family, DEv-IgG fold [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 443959 [Multi-domain]  Cd Length: 689  Bit Score: 56.52  E-value: 4.73e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564918461 187 GLAGYRVELIDAAGEAVAVSATGSAGQFAFQGFDAGTYALVVTDTLTGLGVARADA------FAVEPGSV--LIDRNIAV 258
Cdd:COG4932   179 PLPGATFTLYDSDGTLVKTVTTDADGKYTFTDLPPGTYTLTETKAPEGYVLDTKDPtgatitVTVNAGGTvtVTLKNTPK 258

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564918461 259 NPTG----VVFDAISGAPVTGAVVRLVDAEGEplppacLLPGQQGQMTGASGQYRLSIVfgaapqcPAGrtTYRI-AVAP 333
Cdd:COG4932   259 YTKGsvtvTKTDADTGEPLAGATFTLTDADGN------TVVTTTVTVTDADGSYTFTDL-------PPG--TYTVtETKA 323


                  ....*.
gi 2564918461 334 PGGYEP 339
Cdd:COG4932   324 PAGYDL 329
DUF11 super family cl47654
Domain of unknown function DUF11; A domain of unknown function found in multiple copies in ...
 411-502 3.22e-07

Domain of unknown function DUF11; A domain of unknown function found in multiple copies in several archaebacterial proteins. Conserved N-terminal lysine and C-terminal asparagine with central asp/glu suggests that many of these domain may contain an isopeptide bond. In Methanothermobacter sp. CaT2, a DUF11-containing repeat hypothetical protein encoded by MTCT_1020 plays a key role as a membrane-bound adhesion protein in the aggregation of CaT2. DUF11-containing repeat domains are not involved in aggregation, but may be important for stabilizing the surface cell wall structures of CaT2.


The actual alignment was detected with superfamily member pfam01345:

Pssm-ID: 460168 [Multi-domain]  Cd Length: 114  Bit Score: 49.53  E-value: 3.22e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564918461 411 LSVSKTADSAAARQGDVVVLTVDIANDGEVTADTLTLVERLPDPLVYAPGTArvDGAAFEPETagrGLRFGPlELAPGQS 490
Cdd:pfam01345   2 LAITKTVDNTTPNVGDTVTFTITVTNNGPSDATGVVVTDTLPAGLTFVSATA--SQGTYDSAT---GIWTIG-SLAVGAS 75

                          90
                  ....*....|..
gi 2564918461 491 ATVRFEARVTDA 502
Cdd:pfam01345  76 ATLTITATVNTA 87
SdrD_B super family cl25441
SdrD B-like domain; This family corresponds to the B-like domain from the SdrD protein. This ...
 543-579 9.26e-03

SdrD B-like domain; This family corresponds to the B-like domain from the SdrD protein. This domain has three calcium binding sites within a greek key beta sandwich fold.


The actual alignment was detected with superfamily member pfam17210:

Pssm-ID: 435789 [Multi-domain]  Cd Length: 112  Bit Score: 36.42  E-value: 9.26e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 2564918461 543 IGGVVFVDANRNAAMDPAERGIADVRLT---ADGGIVATT 579
Cdd:pfam17210   3 IGDFVWEDANKNGIQDAGEPGISGVTVTlydANGTVVGTT 42
 
Name Accession Description Interval E-value
ClfA COG4932
Clumping factor A-related surface protein, MSCRAMM (microbial surface components recognizing ...
 187-339 4.73e-08

Clumping factor A-related surface protein, MSCRAMM (microbial surface components recognizing adhesive matrix molecules) family, DEv-IgG fold [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443959 [Multi-domain]  Cd Length: 689  Bit Score: 56.52  E-value: 4.73e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564918461 187 GLAGYRVELIDAAGEAVAVSATGSAGQFAFQGFDAGTYALVVTDTLTGLGVARADA------FAVEPGSV--LIDRNIAV 258
Cdd:COG4932   179 PLPGATFTLYDSDGTLVKTVTTDADGKYTFTDLPPGTYTLTETKAPEGYVLDTKDPtgatitVTVNAGGTvtVTLKNTPK 258

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564918461 259 NPTG----VVFDAISGAPVTGAVVRLVDAEGEplppacLLPGQQGQMTGASGQYRLSIVfgaapqcPAGrtTYRI-AVAP 333
Cdd:COG4932   259 YTKGsvtvTKTDADTGEPLAGATFTLTDADGN------TVVTTTVTVTDADGSYTFTDL-------PPG--TYTVtETKA 323


                  ....*.
gi 2564918461 334 PGGYEP 339
Cdd:COG4932   324 PAGYDL 329
DUF11 pfam01345
Domain of unknown function DUF11; A domain of unknown function found in multiple copies in ...
 411-502 3.22e-07

Domain of unknown function DUF11; A domain of unknown function found in multiple copies in several archaebacterial proteins. Conserved N-terminal lysine and C-terminal asparagine with central asp/glu suggests that many of these domain may contain an isopeptide bond. In Methanothermobacter sp. CaT2, a DUF11-containing repeat hypothetical protein encoded by MTCT_1020 plays a key role as a membrane-bound adhesion protein in the aggregation of CaT2. DUF11-containing repeat domains are not involved in aggregation, but may be important for stabilizing the surface cell wall structures of CaT2.


Pssm-ID: 460168 [Multi-domain]  Cd Length: 114  Bit Score: 49.53  E-value: 3.22e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564918461 411 LSVSKTADSAAARQGDVVVLTVDIANDGEVTADTLTLVERLPDPLVYAPGTArvDGAAFEPETagrGLRFGPlELAPGQS 490
Cdd:pfam01345   2 LAITKTVDNTTPNVGDTVTFTITVTNNGPSDATGVVVTDTLPAGLTFVSATA--SQGTYDSAT---GIWTIG-SLAVGAS 75

                          90
                  ....*....|..
gi 2564918461 491 ATVRFEARVTDA 502
Cdd:pfam01345  76 ATLTITATVNTA 87
B_ant_repeat TIGR01451
conserved repeat domain; This model represents the conserved region of about 53 amino acids ...
 415-466 2.64e-06

conserved repeat domain; This model represents the conserved region of about 53 amino acids shared between regions, usually repeated, of proteins from a small number of phylogenetically distant prokaryotes. Examples include a 132-residue region found repeated in three of the five longest proteins of Bacillus anthracis, a 131-residue repeat in a cell wall-anchored protein of Enterococcus faecalis, and a 120-residue repeat in Methanobacterium thermoautotrophicum. A similar region is found in some Chlamydial outer membrane proteins.


Pssm-ID: 273634 [Multi-domain]  Cd Length: 53  Bit Score: 44.91  E-value: 2.64e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2564918461 415 KTADSAAARQGDVVVLTVDIANDGEVTADTLTLVERLPDPLVYAPGTARVDG 466
Cdd:TIGR01451   1 KTVDKTVATIGDTITYTITVTNNGNVPATNVVVTDILPAGTTFVSNSVTVNG 52
MJ0795 COG1361
S-layer protein MJ0795, predicted component of type IV pili-like system [General function ...
 411-537 1.48e-05

S-layer protein MJ0795, predicted component of type IV pili-like system [General function prediction only];


Pssm-ID: 440972 [Multi-domain]  Cd Length: 409  Bit Score: 48.15  E-value: 1.48e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564918461 411 LSVSKTADSAAARQGDVVVLTVDIANDGEVTAD--TLTLVERLPDPLVYAPGTARVDGAAFEPETAgrglrFGPLE---- 484
Cdd:COG1361   138 FEVVSVTSPDSLTPGDTGTLTLTIKNTGTGTAKnvTVTLTSPSGDLTDLEPGPRPATNVVVVLSSP-----VSPVGsnsv 212

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2564918461 485 ----LAPGQSATVRFEARVTDAAVSG--VVDAVSQLLGGDGRAAARPARVRLRIEGLAD 537
Cdd:COG1361   213 algtLEPGESATFTFKVDVSEDAEPGpyPLPLTVTYRDEDGDTYSDTVTIGVYVAPKAD 271
SdrD_B pfam17210
SdrD B-like domain; This family corresponds to the B-like domain from the SdrD protein. This ...
 543-579 9.26e-03

SdrD B-like domain; This family corresponds to the B-like domain from the SdrD protein. This domain has three calcium binding sites within a greek key beta sandwich fold.


Pssm-ID: 435789 [Multi-domain]  Cd Length: 112  Bit Score: 36.42  E-value: 9.26e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 2564918461 543 IGGVVFVDANRNAAMDPAERGIADVRLT---ADGGIVATT 579
Cdd:pfam17210   3 IGDFVWEDANKNGIQDAGEPGISGVTVTlydANGTVVGTT 42
 
Name Accession Description Interval E-value
ClfA COG4932
Clumping factor A-related surface protein, MSCRAMM (microbial surface components recognizing ...
 187-339 4.73e-08

Clumping factor A-related surface protein, MSCRAMM (microbial surface components recognizing adhesive matrix molecules) family, DEv-IgG fold [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443959 [Multi-domain]  Cd Length: 689  Bit Score: 56.52  E-value: 4.73e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564918461 187 GLAGYRVELIDAAGEAVAVSATGSAGQFAFQGFDAGTYALVVTDTLTGLGVARADA------FAVEPGSV--LIDRNIAV 258
Cdd:COG4932   179 PLPGATFTLYDSDGTLVKTVTTDADGKYTFTDLPPGTYTLTETKAPEGYVLDTKDPtgatitVTVNAGGTvtVTLKNTPK 258

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564918461 259 NPTG----VVFDAISGAPVTGAVVRLVDAEGEplppacLLPGQQGQMTGASGQYRLSIVfgaapqcPAGrtTYRI-AVAP 333
Cdd:COG4932   259 YTKGsvtvTKTDADTGEPLAGATFTLTDADGN------TVVTTTVTVTDADGSYTFTDL-------PPG--TYTVtETKA 323


                  ....*.
gi 2564918461 334 PGGYEP 339
Cdd:COG4932   324 PAGYDL 329
DUF11 pfam01345
Domain of unknown function DUF11; A domain of unknown function found in multiple copies in ...
 411-502 3.22e-07

Domain of unknown function DUF11; A domain of unknown function found in multiple copies in several archaebacterial proteins. Conserved N-terminal lysine and C-terminal asparagine with central asp/glu suggests that many of these domain may contain an isopeptide bond. In Methanothermobacter sp. CaT2, a DUF11-containing repeat hypothetical protein encoded by MTCT_1020 plays a key role as a membrane-bound adhesion protein in the aggregation of CaT2. DUF11-containing repeat domains are not involved in aggregation, but may be important for stabilizing the surface cell wall structures of CaT2.


Pssm-ID: 460168 [Multi-domain]  Cd Length: 114  Bit Score: 49.53  E-value: 3.22e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564918461 411 LSVSKTADSAAARQGDVVVLTVDIANDGEVTADTLTLVERLPDPLVYAPGTArvDGAAFEPETagrGLRFGPlELAPGQS 490
Cdd:pfam01345   2 LAITKTVDNTTPNVGDTVTFTITVTNNGPSDATGVVVTDTLPAGLTFVSATA--SQGTYDSAT---GIWTIG-SLAVGAS 75

                          90
                  ....*....|..
gi 2564918461 491 ATVRFEARVTDA 502
Cdd:pfam01345  76 ATLTITATVNTA 87
B_ant_repeat TIGR01451
conserved repeat domain; This model represents the conserved region of about 53 amino acids ...
 415-466 2.64e-06

conserved repeat domain; This model represents the conserved region of about 53 amino acids shared between regions, usually repeated, of proteins from a small number of phylogenetically distant prokaryotes. Examples include a 132-residue region found repeated in three of the five longest proteins of Bacillus anthracis, a 131-residue repeat in a cell wall-anchored protein of Enterococcus faecalis, and a 120-residue repeat in Methanobacterium thermoautotrophicum. A similar region is found in some Chlamydial outer membrane proteins.


Pssm-ID: 273634 [Multi-domain]  Cd Length: 53  Bit Score: 44.91  E-value: 2.64e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2564918461 415 KTADSAAARQGDVVVLTVDIANDGEVTADTLTLVERLPDPLVYAPGTARVDG 466
Cdd:TIGR01451   1 KTVDKTVATIGDTITYTITVTNNGNVPATNVVVTDILPAGTTFVSNSVTVNG 52
ClfA COG4932
Clumping factor A-related surface protein, MSCRAMM (microbial surface components recognizing ...
 185-288 4.93e-06

Clumping factor A-related surface protein, MSCRAMM (microbial surface components recognizing adhesive matrix molecules) family, DEv-IgG fold [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443959 [Multi-domain]  Cd Length: 689  Bit Score: 49.97  E-value: 4.93e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564918461 185 DPGLAGYRVELIDAAGEAVAVSATGSAGQFAFQGFDAGTYALVVTDTLTG-LGVARADAFAVEPGSVLIDRNIA-VNPTG 262
Cdd:COG4932   371 EAPLAGAEFTLTDADGTVVATITTDADGTASFKGLAPGTYTLTETKAPEGyTLDSTPITVTVTDGGTGAIDTITnERKKG 450

                          90       100
                  ....*....|....*....|....*.
gi 2564918461 263 VVFDAISGAPVTGAVVRLVDAEGEPL 288
Cdd:COG4932   451 SVQVTKVDAPLAGATFTLTDADGTVV 476
MJ0795 COG1361
S-layer protein MJ0795, predicted component of type IV pili-like system [General function ...
 411-537 1.48e-05

S-layer protein MJ0795, predicted component of type IV pili-like system [General function prediction only];


Pssm-ID: 440972 [Multi-domain]  Cd Length: 409  Bit Score: 48.15  E-value: 1.48e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564918461 411 LSVSKTADSAAARQGDVVVLTVDIANDGEVTAD--TLTLVERLPDPLVYAPGTARVDGAAFEPETAgrglrFGPLE---- 484
Cdd:COG1361   138 FEVVSVTSPDSLTPGDTGTLTLTIKNTGTGTAKnvTVTLTSPSGDLTDLEPGPRPATNVVVVLSSP-----VSPVGsnsv 212

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2564918461 485 ----LAPGQSATVRFEARVTDAAVSG--VVDAVSQLLGGDGRAAARPARVRLRIEGLAD 537
Cdd:COG1361   213 algtLEPGESATFTFKVDVSEDAEPGpyPLPLTVTYRDEDGDTYSDTVTIGVYVAPKAD 271
MJ0795 COG1361
S-layer protein MJ0795, predicted component of type IV pili-like system [General function ...
 423-506 2.04e-03

S-layer protein MJ0795, predicted component of type IV pili-like system [General function prediction only];


Pssm-ID: 440972 [Multi-domain]  Cd Length: 409  Bit Score: 41.22  E-value: 2.04e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2564918461 423 RQGDVVVLTVDIANDGEVTADTLTLVERLPDPLVYAPGTARVDgaafepetagrglrfgplELAPGQSATVRFEARVTDA 502
Cdd:COG1361   282 TAGETVTITITVTNTGNETAKNVVARLSADDPLSSLDDEAFIG------------------DLAPGESATVTFTVSASSD 343


                  ....
gi 2564918461 503 AVSG 506
Cdd:COG1361   344 ATPG 347
SdrD_B pfam17210
SdrD B-like domain; This family corresponds to the B-like domain from the SdrD protein. This ...
 543-579 9.26e-03

SdrD B-like domain; This family corresponds to the B-like domain from the SdrD protein. This domain has three calcium binding sites within a greek key beta sandwich fold.


Pssm-ID: 435789 [Multi-domain]  Cd Length: 112  Bit Score: 36.42  E-value: 9.26e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 2564918461 543 IGGVVFVDANRNAAMDPAERGIADVRLT---ADGGIVATT 579
Cdd:pfam17210   3 IGDFVWEDANKNGIQDAGEPGISGVTVTlydANGTVVGTT 42
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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