|
Name |
Accession |
Description |
Interval |
E-value |
| strep_PBP2A |
NF038276 |
streptococcal penicillin-binding protein PBP2A; |
8-728 |
0e+00 |
|
streptococcal penicillin-binding protein PBP2A;
Pssm-ID: 439576 [Multi-domain] Cd Length: 716 Bit Score: 1436.33 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 8 QYQRGiRHQKENAKSRPEWLqkvDRYLPSPKNPIRRFWRRYRIGKLLFIALMAFILIFGSYLFYLSKTATVSDLQSALKT 87
Cdd:NF038276 1 SYQRS-KGYEEKAKKRPAWL---SRIKPSPQNPIRRFWRRYHLGKILLILGGTFVLLVGSYLFYLAKTTNVSDLQNALKA 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 88 TTTIYDKNKEYAGKLSGQKGTYVELNAISDHLKNAVIATEDRTFYENNGVNFKRFFLAVATLGKFGGGSTITQQLAKNAY 167
Cdd:NF038276 77 TTVIYDKDGKEAGSLSGQKGTYVELDAISDDLENAVIATEDRSFYKNSGINYKRFFLAILTAGRFGGGSTITQQLAKNAY 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 168 LSQDQTIKRKAREFFLALELTKKYSKAEILTMYLNNSYFGNGVWGVEDASRKYFGTSAANLTVDEAATLAGMLKGPEVYN 247
Cdd:NF038276 157 LSQDQTIKRKAKEFFLALELTKKYSKKEILTMYLNNAYFGNGVWGVEDASQKYFGTSAANLTLDEAATLAGMLKGPEIYN 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 248 PYYSVENATNRRDTVLAAMVDAGKLTKSQAKEAASIGMKNRLADTYAGKINDYRYPSYFDAVVNEAIDTYGISEKDIVNN 327
Cdd:NF038276 237 PLYSIENATNRRDTVLQNMVDAGKIDQAQADEAAAVDMGSRLADTYEGKSDDYRYPSYFDAVINEAISKYGLSEKDIVNN 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 328 GYKIYTALDQNYQSGMQKTFDDTSLFPVSDYDGQSAQGASVALDPKTGGVRGLVGRVQSTKDAQFRSFNYATQSKRSPAS 407
Cdd:NF038276 317 GYKIYTELDQNYQAGMQVTFDNTSLFPVSEYDGTSAQSASVALDPKTGGVRGLVGRVNSTENATFRSFNYATQSKRSPGS 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 408 TIKPLVVYSPAIASGWSIDKELPNKVQDFHGYKPSNYGGIETESIPMYQALANSYNIPAVYTLDKLGINKAFTYGRKFGL 487
Cdd:NF038276 397 TIKPLVVYSPAVASGWSIDKELPNTTQDYDGYKPHNYGGIESEDVPMYQALANSYNIPAVYTLNELGIDKAFSYGKKFGL 476
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 488 NMSSANKELGVALGGSVTTNPLEMAQAYSTFANDGIMHRAHLITRIETANGKLVKQFTDKPKRVISRSVASKMTSMMLGT 567
Cdd:NF038276 477 NMDKVDKELGVALGGGVTTNPLEMAQAYATFANGGVMPDAHLITRIENASGKVIKTHKDKSKRVISQSVADKMTSMMLGT 556
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 568 FSNGTAINANVYGYTMAGKTGTTETDFNPNLSGDQWVVGYTPDVVISQWVGFKNTDKHHYLTDSSAGTASNIFSTQASYI 647
Cdd:NF038276 557 FSNGTGVNANVYGYTMAGKTGTTETDFNPDLSSDQWVIGYTPDVVISQWLGFPKTDENHYLTDSSSGTASTIFSTVASYI 636
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 648 LPYTKGSSFThIENAYFQNGIGSVYNAQDASNTTNQESRSIINDLKDSASKAAQDISRAVEDSNFQEKVKDAWNSLKDYF 727
Cdd:NF038276 637 LPYTKGTEFT-VENAYAQNGIAPVYTANETSTETSSESQDIIDDIRESAQNAVDSASKAVDDAGIKEKAKSLWDSIVDWF 715
|
.
gi 2566600597 728 R 728
Cdd:NF038276 716 R 716
|
|
| MrcB |
COG0744 |
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall ... |
36-657 |
0e+00 |
|
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440507 [Multi-domain] Cd Length: 630 Bit Score: 629.26 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 36 SPKNPIRRFWRRYRIGKLLFIALMAFILIFGSYLFYLSKTATVSDLQS-ALKTTTTIYDKNKEYAGKLSGQKGTYVELNA 114
Cdd:COG0744 2 AKPRRGKRLLRRLLGLLLLLLAVLVLAALAGLVALYVADLPDPEELEDlALPQTSTIYDRDGTLIATLGDENREWVPLDQ 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 115 ISDHLKNAVIATEDRTFYENNGVNFKRFFLAV---ATLGKF-GGGSTITQQLAKNAYLSQDQTIKRKAREFFLALELTKK 190
Cdd:COG0744 82 IPPHLKDAVVAIEDRRFYEHGGVDPKGIARALvanLTAGGVvQGGSTITQQLVKNLFLSNERTLSRKLKEALLALKLERK 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 191 YSKAEILTMYLNNSYFGNGVWGVEDASRKYFGTSAANLTVDEAATLAGMLKGPEVYNPYYSVENATNRRDTVLAAMVDAG 270
Cdd:COG0744 162 YSKDEILELYLNTVYFGRGAYGIEAAAQYYFGKSASDLTLAEAALLAGLVKAPSYYDPYRNPEAAKERRNLVLDRMVEQG 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 271 KLTKSQAKEA--ASIGMKNRLADTYAGKindyrYPSYFDAVVNEAIDTYGisEKDIVNNGYKIYTALDQNYQSGMQKTFD 348
Cdd:COG0744 242 YITQAEADAAkaEPLTLVPPPNGAAAGK-----YPYFVDYVRRELEELLG--EDDLYRGGLKIYTTLDPKLQKAAEKAVK 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 349 DTslFPVSDYDGqsAQGASVALDPKTGGVRGLVGRvqstKDAQFRSFNYATQSKRSPASTIKPLvVYSPAIASGWSIDKE 428
Cdd:COG0744 315 NV--LPEGKPGG--LQAALVVVDPKTGEVLAMVGG----RDYGKSQFNRATQAKRQPGSTFKPF-VYAAALEQGYTPATT 385
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 429 LPNKVQDFHG--YKPSNYGGIETESIPMYQALANSYNIPAVYTLDKLGINKAFTYGRKFGLNmSSANKELGVALgGSVTT 506
Cdd:COG0744 386 VDDEPVTFPGggWSPKNYDGRYRGPVTLREALANSLNTPAVRLAQEVGLDKVVDTARRLGIT-SPLDPNPSLAL-GTSEV 463
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 507 NPLEMAQAYSTFANDGIMHRAHLITRIETANGKLVKQFTDKPKRVISRSVASKMTSMMLGTFSNGTAINANVYGYTMAGK 586
Cdd:COG0744 464 SPLEMASAYATFANGGVYVEPHAITKVTDADGKVLYEAKPKCEQVISPEVAYLMTDMLQDVVTSGTGRAARLPGRPVAGK 543
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2566600597 587 TGTTetdfnpNLSGDQWVVGYTPDVVISQWVGFKNTDKHHYLTdsSAGTASNIFSTQASYILPYTKGSSFT 657
Cdd:COG0744 544 TGTT------NDNRDAWFVGYTPQLVTAVWVGNDDNSPMGYVT--GGSLPAPIWRDFMEAALEGLPVEDFP 606
|
|
| PBP_1a_fam |
TIGR02074 |
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan ... |
106-650 |
0e+00 |
|
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273955 [Multi-domain] Cd Length: 531 Bit Score: 568.04 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 106 KGTYVELNAISDHLKNAVIATEDRTFYENNGVNFKRFFLA-VATL---GKFGGGSTITQQLAKNAYLSQDQTIKRKAREF 181
Cdd:TIGR02074 1 RREYVPIDDIPENLINAFLAIEDRRFYDHFGIDLKGIGRAaVANItsgRVLEGGSTITQQLAKNLYLTNERTITRKIQEA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 182 FLALELTKKYSKAEILTMYLNNSYFGNGVWGVEDASRKYFGTSAANLTVDEAATLAGMLKGPEVYNPYYSVENATNRRDT 261
Cdd:TIGR02074 81 LLALKLEQKLSKDEILELYLNRIYFGNGAYGIEAAAQFYFGKSVNDLTLAEAAMLAGLPKAPSAYNPFKNPERAKDRRNL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 262 VLAAMVDAGKLTKSQAKEAasigmKNRLADTY--AGKINDYRYPSYFDAVVNEAIDTYGiseKDIVNNGYKIYTALDQNY 339
Cdd:TIGR02074 161 VLSNMVENGYITAEEAEEA-----INEPIQLYlqTKKSEQYKAPYFVDYVIQELEEEYG---EELYTGGLKIYTTLDLDA 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 340 QSGMQKTFDDTSLFPVSDyDGQSAQGASVALDPKTGGVRGLVGrvqsTKDAQFRSFNYATQSKRSPASTIKPLvVYSPAI 419
Cdd:TIGR02074 233 QKAAEKVLNTGLRVAGRR-DGDDLQAALVAIDPDTGAVRALVG----GRDYGKSQFNRATQAKRQPGSTFKPF-VYAAAL 306
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 420 ASGWSIDKEL---PNKVQDFHGYKPSNYGGIETESIPMYQALANSYNIPAVYTLDKLGINKAFTYGRKFGLNmSSANKEL 496
Cdd:TIGR02074 307 EKGLTPATIVndePITYNGNGPWSPKNYGGGYRGNVTLRQALAQSRNIPAVRLLQEVGLDKVVALAKRFGIT-SPLDPVL 385
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 497 GVALgGSVTTNPLEMAQAYSTFANDGIMHRAHLITRIETANGKLVKQFTDKPKRVISRSVASKMTSMMLGTFSNGTAINA 576
Cdd:TIGR02074 386 SLAL-GTVEVSPLEMASAYAVFANGGKYVEPHGIRKIVDRDGKVIYENKPKTTQVISPATAYIMTDMLKGVVESGTGRSA 464
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2566600597 577 NVYGYTMAGKTGTTetdfnpNLSGDQWVVGYTPDVVISQWVGFKNTdKHHYLTDSSAGTASNIFSTQASYILPY 650
Cdd:TIGR02074 465 RLPGRPVAGKTGTT------QNWRDAWFVGYTPYYVTAVWVGYDDK-KTLGKSGTGGGLAAPIWRDFMAEALKN 531
|
|
| Transgly |
pfam00912 |
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of ... |
100-267 |
2.92e-77 |
|
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of transglycosylase and transpeptidase in the N- and C-terminus respectively. The transglycosylase domain catalyzes the polymerization of murein glycan chains.
Pssm-ID: 459993 [Multi-domain] Cd Length: 177 Bit Score: 245.51 E-value: 2.92e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 100 GKLSGQKGTYVELNAISDHLKNAVIATEDRTFYENNGVNFKRFFLAVATLGKFG----GGSTITQQLAKNAYLSQDQTIK 175
Cdd:pfam00912 6 AELGEENREYVPLDDIPPALKNAVLAIEDRRFYEHGGVDPKGIARALLSNLRSGrivqGGSTITQQLAKNLFLTPERTLT 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 176 RKAREFFLALELTKKYSKAEILTMYLNNSYFGNGVWGVEDASRKYFGTSAANLTVDEAATLAGMLKGPEVYNPYYSVENA 255
Cdd:pfam00912 86 RKLKEAVLALKLERRYSKDEILEAYLNTVYFGRGAYGIEAAARAYFGKDASDLTLAEAALLAGLPQAPSRYNPLRNPERA 165
|
170
....*....|..
gi 2566600597 256 TNRRDTVLAAMV 267
Cdd:pfam00912 166 KRRRNLVLDRMV 177
|
|
| mrcA |
PRK11636 |
penicillin-binding protein 1a; Provisional |
52-645 |
1.74e-63 |
|
penicillin-binding protein 1a; Provisional
Pssm-ID: 183248 [Multi-domain] Cd Length: 850 Bit Score: 227.32 E-value: 1.74e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 52 KLLFIALMAFIL-----IFGSYLFY---LSKTATVSDLQsaLKTTTTIYDKNKEYAGKLSGQKGTYVELNAISDHLKNAV 123
Cdd:PRK11636 5 KYLLILAVCCILlgagsIYGLYRYIepqLPDVATLKDVR--LQTPMQVYSADGELIAQYGEKRRIPLTLDQIPPEMVKAF 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 124 IATEDRTFYENNGVNFKRFFLAVATLGKFG----GGSTITQQLAKNAYLSQDQTIKRKAREFFLALELTKKYSKAEILTM 199
Cdd:PRK11636 83 IATEDSRFYEHHGVDPVGIFRAASVALFSGhasqGASTITQQLARNFFLSPERTLMRKIKEAFLAIRIEQLLTKDEILEL 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 200 YLNNSYFGNGVWGVEDASRKYFGTSAANLTVDEAATLAGMLKGPEVYNPYYSVENATNRRDTVLAAMVDAGKLTKSQAKE 279
Cdd:PRK11636 163 YLNKIYLGYRAYGVGAAAQVYFGKTVDQLTLSEMAVIAGLPKAPSTFNPLYSMDRAVARRNVVLSRMLDEGYITQAQYDQ 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 280 AASIGMknrLADTYAGKInDYRYPSYFDAVVNEAIDTYGiseKDIVNNGYKIYTALDQNYQSGMQKTFDDTslfpVSDYD 359
Cdd:PRK11636 243 ARSEPI---VANYHAPEI-AFSAPYLSEMVRQEMYNRYG---ENAYEDGYRVYTTITRKVQQAAQQAVRNN----VLDYD 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 360 ---------------GQSA------------------------------------------------------------Q 364
Cdd:PRK11636 312 mrhgyrgpanvlwkvGESAwdnkkitdtlkalptygpllpavvtsanpqeatamladgssvalpmegvrwarpyrsdtqQ 391
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 365 GAS-----------------------------------VALDPKTGGVRGLVGRVqstkDAQFRSFNYATQSKRSPASTI 409
Cdd:PRK11636 392 GPTprkvtdvvqtgqqiwvrqvddawwlaqvpdvnsalVSINPQNGAVMALVGGF----DFNQSKFNRATQALRQVGSNI 467
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 410 KPLvVYSPAIASGW---SIDKELPNKVQDFHG---YKPSN----YGGieteSIPMYQALANSYNIPAVYTLDKLGINKAF 479
Cdd:PRK11636 468 KPF-LYTAAMDKGLtlaSMLNDVPISRWDAGAgsdWRPKNsppqYAG----PIRLRQGLGQSKNVVMVRAMRAMGVDYAA 542
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 480 TYGRKFGLNMSSANKELGVALgGSVTTNPLEMAQAYSTFANDGIMHRAHLITRIETANGKLVkqFTDKPKRVIS------ 553
Cdd:PRK11636 543 EYLQRFGFPAQNIVHTESLAL-GSASFTPMQVARGYAVMANGGFLVDPYFISKIENDQGGVI--FEAKPKVACPecdipv 619
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 554 ------RSVASKMTSM--------------------------------------MLGT---FSNGTAINANVYG------ 580
Cdd:PRK11636 620 iygdtqKSNVLENDDVenvatsqeqqnssvpmpqleqanqalvaqngaqeyaphVINTplaFLIKSALNTNIFGepgwmg 699
|
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2566600597 581 -----------YTMAGKTGTTetdfnpNLSGDQWVVGYTPDVVISQWVGFkntDKHHylTDSSAGTASNIFSTQAS 645
Cdd:PRK11636 700 tgwragrdlkrRDIGGKTGTT------NSSKDAWFSGYGPGVVTSVWIGF---DDHR--RDLGRTTASGAIKDQIS 764
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| strep_PBP2A |
NF038276 |
streptococcal penicillin-binding protein PBP2A; |
8-728 |
0e+00 |
|
streptococcal penicillin-binding protein PBP2A;
Pssm-ID: 439576 [Multi-domain] Cd Length: 716 Bit Score: 1436.33 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 8 QYQRGiRHQKENAKSRPEWLqkvDRYLPSPKNPIRRFWRRYRIGKLLFIALMAFILIFGSYLFYLSKTATVSDLQSALKT 87
Cdd:NF038276 1 SYQRS-KGYEEKAKKRPAWL---SRIKPSPQNPIRRFWRRYHLGKILLILGGTFVLLVGSYLFYLAKTTNVSDLQNALKA 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 88 TTTIYDKNKEYAGKLSGQKGTYVELNAISDHLKNAVIATEDRTFYENNGVNFKRFFLAVATLGKFGGGSTITQQLAKNAY 167
Cdd:NF038276 77 TTVIYDKDGKEAGSLSGQKGTYVELDAISDDLENAVIATEDRSFYKNSGINYKRFFLAILTAGRFGGGSTITQQLAKNAY 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 168 LSQDQTIKRKAREFFLALELTKKYSKAEILTMYLNNSYFGNGVWGVEDASRKYFGTSAANLTVDEAATLAGMLKGPEVYN 247
Cdd:NF038276 157 LSQDQTIKRKAKEFFLALELTKKYSKKEILTMYLNNAYFGNGVWGVEDASQKYFGTSAANLTLDEAATLAGMLKGPEIYN 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 248 PYYSVENATNRRDTVLAAMVDAGKLTKSQAKEAASIGMKNRLADTYAGKINDYRYPSYFDAVVNEAIDTYGISEKDIVNN 327
Cdd:NF038276 237 PLYSIENATNRRDTVLQNMVDAGKIDQAQADEAAAVDMGSRLADTYEGKSDDYRYPSYFDAVINEAISKYGLSEKDIVNN 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 328 GYKIYTALDQNYQSGMQKTFDDTSLFPVSDYDGQSAQGASVALDPKTGGVRGLVGRVQSTKDAQFRSFNYATQSKRSPAS 407
Cdd:NF038276 317 GYKIYTELDQNYQAGMQVTFDNTSLFPVSEYDGTSAQSASVALDPKTGGVRGLVGRVNSTENATFRSFNYATQSKRSPGS 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 408 TIKPLVVYSPAIASGWSIDKELPNKVQDFHGYKPSNYGGIETESIPMYQALANSYNIPAVYTLDKLGINKAFTYGRKFGL 487
Cdd:NF038276 397 TIKPLVVYSPAVASGWSIDKELPNTTQDYDGYKPHNYGGIESEDVPMYQALANSYNIPAVYTLNELGIDKAFSYGKKFGL 476
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 488 NMSSANKELGVALGGSVTTNPLEMAQAYSTFANDGIMHRAHLITRIETANGKLVKQFTDKPKRVISRSVASKMTSMMLGT 567
Cdd:NF038276 477 NMDKVDKELGVALGGGVTTNPLEMAQAYATFANGGVMPDAHLITRIENASGKVIKTHKDKSKRVISQSVADKMTSMMLGT 556
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 568 FSNGTAINANVYGYTMAGKTGTTETDFNPNLSGDQWVVGYTPDVVISQWVGFKNTDKHHYLTDSSAGTASNIFSTQASYI 647
Cdd:NF038276 557 FSNGTGVNANVYGYTMAGKTGTTETDFNPDLSSDQWVIGYTPDVVISQWLGFPKTDENHYLTDSSSGTASTIFSTVASYI 636
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 648 LPYTKGSSFThIENAYFQNGIGSVYNAQDASNTTNQESRSIINDLKDSASKAAQDISRAVEDSNFQEKVKDAWNSLKDYF 727
Cdd:NF038276 637 LPYTKGTEFT-VENAYAQNGIAPVYTANETSTETSSESQDIIDDIRESAQNAVDSASKAVDDAGIKEKAKSLWDSIVDWF 715
|
.
gi 2566600597 728 R 728
Cdd:NF038276 716 R 716
|
|
| MrcB |
COG0744 |
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall ... |
36-657 |
0e+00 |
|
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440507 [Multi-domain] Cd Length: 630 Bit Score: 629.26 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 36 SPKNPIRRFWRRYRIGKLLFIALMAFILIFGSYLFYLSKTATVSDLQS-ALKTTTTIYDKNKEYAGKLSGQKGTYVELNA 114
Cdd:COG0744 2 AKPRRGKRLLRRLLGLLLLLLAVLVLAALAGLVALYVADLPDPEELEDlALPQTSTIYDRDGTLIATLGDENREWVPLDQ 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 115 ISDHLKNAVIATEDRTFYENNGVNFKRFFLAV---ATLGKF-GGGSTITQQLAKNAYLSQDQTIKRKAREFFLALELTKK 190
Cdd:COG0744 82 IPPHLKDAVVAIEDRRFYEHGGVDPKGIARALvanLTAGGVvQGGSTITQQLVKNLFLSNERTLSRKLKEALLALKLERK 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 191 YSKAEILTMYLNNSYFGNGVWGVEDASRKYFGTSAANLTVDEAATLAGMLKGPEVYNPYYSVENATNRRDTVLAAMVDAG 270
Cdd:COG0744 162 YSKDEILELYLNTVYFGRGAYGIEAAAQYYFGKSASDLTLAEAALLAGLVKAPSYYDPYRNPEAAKERRNLVLDRMVEQG 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 271 KLTKSQAKEA--ASIGMKNRLADTYAGKindyrYPSYFDAVVNEAIDTYGisEKDIVNNGYKIYTALDQNYQSGMQKTFD 348
Cdd:COG0744 242 YITQAEADAAkaEPLTLVPPPNGAAAGK-----YPYFVDYVRRELEELLG--EDDLYRGGLKIYTTLDPKLQKAAEKAVK 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 349 DTslFPVSDYDGqsAQGASVALDPKTGGVRGLVGRvqstKDAQFRSFNYATQSKRSPASTIKPLvVYSPAIASGWSIDKE 428
Cdd:COG0744 315 NV--LPEGKPGG--LQAALVVVDPKTGEVLAMVGG----RDYGKSQFNRATQAKRQPGSTFKPF-VYAAALEQGYTPATT 385
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 429 LPNKVQDFHG--YKPSNYGGIETESIPMYQALANSYNIPAVYTLDKLGINKAFTYGRKFGLNmSSANKELGVALgGSVTT 506
Cdd:COG0744 386 VDDEPVTFPGggWSPKNYDGRYRGPVTLREALANSLNTPAVRLAQEVGLDKVVDTARRLGIT-SPLDPNPSLAL-GTSEV 463
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 507 NPLEMAQAYSTFANDGIMHRAHLITRIETANGKLVKQFTDKPKRVISRSVASKMTSMMLGTFSNGTAINANVYGYTMAGK 586
Cdd:COG0744 464 SPLEMASAYATFANGGVYVEPHAITKVTDADGKVLYEAKPKCEQVISPEVAYLMTDMLQDVVTSGTGRAARLPGRPVAGK 543
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2566600597 587 TGTTetdfnpNLSGDQWVVGYTPDVVISQWVGFKNTDKHHYLTdsSAGTASNIFSTQASYILPYTKGSSFT 657
Cdd:COG0744 544 TGTT------NDNRDAWFVGYTPQLVTAVWVGNDDNSPMGYVT--GGSLPAPIWRDFMEAALEGLPVEDFP 606
|
|
| PBP_1a_fam |
TIGR02074 |
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan ... |
106-650 |
0e+00 |
|
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273955 [Multi-domain] Cd Length: 531 Bit Score: 568.04 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 106 KGTYVELNAISDHLKNAVIATEDRTFYENNGVNFKRFFLA-VATL---GKFGGGSTITQQLAKNAYLSQDQTIKRKAREF 181
Cdd:TIGR02074 1 RREYVPIDDIPENLINAFLAIEDRRFYDHFGIDLKGIGRAaVANItsgRVLEGGSTITQQLAKNLYLTNERTITRKIQEA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 182 FLALELTKKYSKAEILTMYLNNSYFGNGVWGVEDASRKYFGTSAANLTVDEAATLAGMLKGPEVYNPYYSVENATNRRDT 261
Cdd:TIGR02074 81 LLALKLEQKLSKDEILELYLNRIYFGNGAYGIEAAAQFYFGKSVNDLTLAEAAMLAGLPKAPSAYNPFKNPERAKDRRNL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 262 VLAAMVDAGKLTKSQAKEAasigmKNRLADTY--AGKINDYRYPSYFDAVVNEAIDTYGiseKDIVNNGYKIYTALDQNY 339
Cdd:TIGR02074 161 VLSNMVENGYITAEEAEEA-----INEPIQLYlqTKKSEQYKAPYFVDYVIQELEEEYG---EELYTGGLKIYTTLDLDA 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 340 QSGMQKTFDDTSLFPVSDyDGQSAQGASVALDPKTGGVRGLVGrvqsTKDAQFRSFNYATQSKRSPASTIKPLvVYSPAI 419
Cdd:TIGR02074 233 QKAAEKVLNTGLRVAGRR-DGDDLQAALVAIDPDTGAVRALVG----GRDYGKSQFNRATQAKRQPGSTFKPF-VYAAAL 306
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 420 ASGWSIDKEL---PNKVQDFHGYKPSNYGGIETESIPMYQALANSYNIPAVYTLDKLGINKAFTYGRKFGLNmSSANKEL 496
Cdd:TIGR02074 307 EKGLTPATIVndePITYNGNGPWSPKNYGGGYRGNVTLRQALAQSRNIPAVRLLQEVGLDKVVALAKRFGIT-SPLDPVL 385
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 497 GVALgGSVTTNPLEMAQAYSTFANDGIMHRAHLITRIETANGKLVKQFTDKPKRVISRSVASKMTSMMLGTFSNGTAINA 576
Cdd:TIGR02074 386 SLAL-GTVEVSPLEMASAYAVFANGGKYVEPHGIRKIVDRDGKVIYENKPKTTQVISPATAYIMTDMLKGVVESGTGRSA 464
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2566600597 577 NVYGYTMAGKTGTTetdfnpNLSGDQWVVGYTPDVVISQWVGFKNTdKHHYLTDSSAGTASNIFSTQASYILPY 650
Cdd:TIGR02074 465 RLPGRPVAGKTGTT------QNWRDAWFVGYTPYYVTAVWVGYDDK-KTLGKSGTGGGLAAPIWRDFMAEALKN 531
|
|
| MrcA |
COG5009 |
Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis]; |
42-640 |
1.53e-146 |
|
Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 444033 [Multi-domain] Cd Length: 785 Bit Score: 446.91 E-value: 1.53e-146
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 42 RRFWRRyrIGKLLFIALMAFILIFGSYLFYLSKTA-TVSDLQSA-LKTTTTIYDKNkeyaGKLSG----QKGTYVELNAI 115
Cdd:COG5009 1 MRLLKI--LLILLLLLLLLGALAVAGLYLYLSPDLpDVETLKDYqPPTPSRVYSAD----GKLIAefgeERRIPVPIEEI 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 116 SDHLKNAVIATEDRTFYENNGVNFKRFFLAVATL----GKFGGGSTITQQLAKNAYLSQDQTIKRKAREFFLALELTKKY 191
Cdd:COG5009 75 PPLLINAFLAAEDKRFYEHPGVDPIGIARAAVVNlrtgRRVQGGSTITQQVAKNFLLSPERTLTRKIKEAILALRIEQEL 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 192 SKAEILTMYLNNSYFGNGVWGVEDASRKYFGTSAANLTVDEAATLAGMLKGPEVYNPYYSVENATNRRDTVLAAMVDAGK 271
Cdd:COG5009 155 SKDEILELYLNKIYLGHRAYGVAAAAQTYFGKSLDELTLAEAAMLAGLPKAPSRYNPIRNPERALERRNYVLGRMLELGY 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 272 LTKSQAKEAasigMKNRLADTYAGKINDYRYPSYFDAVVNEAIDTYGisEKDIVNNGYKIYTALDQNYQS---------- 341
Cdd:COG5009 235 ITQAEYEAA----KAEPLTARYHGASAEVDAPYFAEMVRRELVERYG--EDALYTGGLKVYTTLDPRLQEaaekalrdgl 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 342 ----------GMQKTFDDTS---------------LFP--VSDYDGQSA------------------------------- 363
Cdd:COG5009 309 laydrrhgyrGPEAHLDLAEedwdealaevpdvgdLRPavVLEVDDKSArvglrdgetgtlpleglkwarpyindnrrgp 388
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 364 ---------------------------------QGASVALDPKTGGVRGLVG-RvqstkDAQFRSFNYATQSKRSPASTI 409
Cdd:COG5009 389 apksasdvlkpgdvirvrpvadggwrlrqipevQGALVALDPHTGAVLALVGgF-----DFEQSKFNRATQAKRQPGSSF 463
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 410 KPLvVYSPAIASGWS-----------IDKELPNKVqdfhgYKPSNYGGIETESIPMYQALANSYNIPAVYTLDKLGINKA 478
Cdd:COG5009 464 KPF-VYAAALDNGYTpatiindapivFDDGGGGGV-----WRPKNYSGKFYGPTTLREALEKSRNLVTVRLLQDVGIDYV 537
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 479 FTYGRKFGLNmSSANKELGVALG-GSVTtnPLEMAQAYSTFANDGIMHRAHLITRIETANGKLVKQFT------------ 545
Cdd:COG5009 538 IDYAERFGIY-SKLPPNLSLALGsGEVT--PLEMARAYAVFANGGYRVEPYLIDRIEDRNGKVIYRADparacedcdaae 614
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 546 ---------DKPKRVISRSVASKMTSMMLGTFSNGTAINANVYGYTMAGKTGTTetdfnpNLSGDQWVVGYTPDVVISQW 616
Cdd:COG5009 615 wdgaeprlpDPAEQVIDPRTAYQMTSMLRGVVQRGTGRRARALGRDIAGKTGTT------NDSKDAWFVGFTPDLVAGVW 688
|
730 740
....*....|....*....|....*.
gi 2566600597 617 VGFkntDKHHYLTDSSAG--TASNIF 640
Cdd:COG5009 689 VGF---DDPRSLGRGETGgrAALPIW 711
|
|
| PBP_1b |
TIGR02071 |
penicillin-binding protein 1B; Bacterial that synthesize a cell wall of peptidoglycan (murein) ... |
100-618 |
2.55e-85 |
|
penicillin-binding protein 1B; Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of a particular bifunctional transglycosylase/transpeptidase in E. coli and other Proteobacteria, designated penicillin-binding protein 1B. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273952 [Multi-domain] Cd Length: 730 Bit Score: 284.69 E-value: 2.55e-85
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 100 GKLSGQKGT---YVELNAISDHLKNAVIATEDRTFYENNGVNFK---RFFLAVATLGK-FGGGSTITQQLAKNAYLSQDQ 172
Cdd:TIGR02071 137 AMLYSPNGEqrlFVPRDQFPELLVDTLLATEDRDFYEHDGISLYsigRAVWVNLTAGRtVQGGSTLTQQLVKNLFLSNER 216
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 173 TIKRKAREFFLALELTKKYSKAEILTMYLNNSYFG----NGVWGVEDASRKYFGTSAANLTVDEAATLAGMLKGPEVYNP 248
Cdd:TIGR02071 217 SLWRKANEAYMALILDARYSKDRILELYLNEVYLGqsgdDAIHGFPLASQYYFGRPLGELSLDQVALLVGMVKGPSYYNP 296
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 249 YYSVENATNRRDTVLAAMVDAGKLTKS--QAKEAASIGMKNRladtyAGKINdyRYPSYFDAVVNEAIDTYGisEKDIVN 326
Cdd:TIGR02071 297 WRNPDRALERRNLVLRLLQEQKIIDDEeyDMLSARPLGVQKK-----GGIIS--RQPAFLQLVRRELRQKLG--DKVKDL 367
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 327 NGYKIYTALDQNYQSGMQKTFDDTslfpVSDYDGQSA----QGASVALDPKTGGVRGLVGrvqsTKDAQFRSFNYATQSK 402
Cdd:TIGR02071 368 SGLRIFTTLDPVSQSAAEQAVQET----IPALKKKKKlpdlEAAMVVTDRFTGEVRAMVG----GSDPQFAGFNRALQAR 439
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 403 RSPASTIKPlVVYSPAIA-------SGWSIDKELPNKVQDFHGYKPSNYGGIETESIPMYQALANSYNIPAVYTLDKLGI 475
Cdd:TIGR02071 440 RQIGSLVKP-AVYLTALSqpdkyrlNTWIEDQPLSIKLSNGQVWSPQNYDRRYSGTVMLYDALAHSLNIPTVNLGMKVGL 518
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 476 NKAFTYGRKFGLNMSSANKELGVALgGSVTTNPLEMAQAYSTFANDGIMHRAHLITRIETANGKLVKQFTDKPKRVISRS 555
Cdd:TIGR02071 519 PKVSQTWNKLGINKDEIPPVPSMLL-GAINLTPYEVAQLYQTIASGGNRAPLSAVRSVLDEDGKVLYQSDPQAEQAVPSQ 597
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2566600597 556 VASKMTSMMLGTFSNGTA--INANVYGYTMAGKTGTTetdfnpNLSGDQWVVGYTPDVVISQWVG 618
Cdd:TIGR02071 598 AAYLTLYAMQQVVQRGTArsLGADFPSLSLAGKTGTT------NDNRDSWFAGIDGKEVTIIWLG 656
|
|
| PbpC |
COG4953 |
Membrane carboxypeptidase/penicillin-binding protein PbpC [Cell wall/membrane/envelope ... |
42-618 |
6.50e-80 |
|
Membrane carboxypeptidase/penicillin-binding protein PbpC [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 443980 [Multi-domain] Cd Length: 773 Bit Score: 270.94 E-value: 6.50e-80
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 42 RRFWRRYRIGKLLFIALMAFILIFGSYLFYLSKtatvsDLQSALKTTTTIYDKNKEYAGKLSGQKGTY---VELNAISDH 118
Cdd:COG4953 2 KRARLRRRRLLALLLALLLLALALWALDRLFPL-----PLLFAVPYSTVVLDRDGTLLRAFLAADGQWrlpVPLDEVSPR 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 119 LKNAVIATEDRTFYENNGVN----FKRFFLAVATLGKFGGGSTITQQLAKnayLSQDQ--TIKRKAREFFLALELTKKYS 192
Cdd:COG4953 77 YLQALLAYEDRRFYYHPGVNplalLRAAWQNLRSGRIVSGGSTLTMQVAR---LLEPRprTLSGKLRQILRALQLERRYS 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 193 KAEILTMYLNNSYFGNGVWGVEDASRKYFGTSAANLTVDEAATLAGMLKGPEVYNPYYSVENATNRRDTVLAAMVDAGKL 272
Cdd:COG4953 154 KDEILELYLNLAPYGGNIEGVEAASLAYFGKPPSRLSLAEAALLAVLPQAPSRRRPDRNPERARAARDRVLARLAEAGVI 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 273 TKSQAKEAasigmknrladtYAGKINDYRYPSYF------DAVVNEAidtygisekdivNNGYKIYTALDQNYQSGMQKT 346
Cdd:COG4953 234 DAEEAALA------------LLEPVPARRRPLPQlaphlaRRLLRQL------------PGGTRIRTTLDAGLQRRLERL 289
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 347 fddtslfpVSDYDGQSAQG-----ASVALDPKTGGVRGLVGRVQSTkDAQFRSFNYATQSKRSPASTIKPLvVYSPAIAS 421
Cdd:COG4953 290 --------VRRYVRRLKQNgihnaAVLVVDNRTGEVLAYVGSADFF-DASRQGQVDMVRALRSPGSTLKPF-LYGLALDQ 359
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 422 GwSIdkeLPNKV-----QDFHGYKPSNYGGIETESIPMYQALANSYNIPAVYTLDKLGINKAFTYGRKFGLNMSSANKE- 495
Cdd:COG4953 360 G-LI---HPETLladvpTSFGGYRPENFDGTFQGPVSAREALARSLNIPAVRLLEALGPARFYARLRRAGLRLLLPPAEh 435
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 496 --LGVALGGsVTTNPLEMAQAYSTFANDGIMHRAHLITrietangklvKQFTDKPKRVISRSVASKMTSMMLGTFSNGTA 573
Cdd:COG4953 436 ygLSLILGG-AEVTLEELVGLYAALARGGEARPLRLLA----------GEPASPGRRLLSPGAAWLVRDILSDVPRPDGA 504
|
570 580 590 600
....*....|....*....|....*....|....*....|....*....
gi 2566600597 574 INANVYG--YTMAGKTGTTetdfnpnlSG--DQWVVGYTPDVVISQWVG 618
Cdd:COG4953 505 FGWRALDspPPIAWKTGTS--------YGfrDAWAVGFTGRYTVGVWVG 545
|
|
| Transgly |
pfam00912 |
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of ... |
100-267 |
2.92e-77 |
|
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of transglycosylase and transpeptidase in the N- and C-terminus respectively. The transglycosylase domain catalyzes the polymerization of murein glycan chains.
Pssm-ID: 459993 [Multi-domain] Cd Length: 177 Bit Score: 245.51 E-value: 2.92e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 100 GKLSGQKGTYVELNAISDHLKNAVIATEDRTFYENNGVNFKRFFLAVATLGKFG----GGSTITQQLAKNAYLSQDQTIK 175
Cdd:pfam00912 6 AELGEENREYVPLDDIPPALKNAVLAIEDRRFYEHGGVDPKGIARALLSNLRSGrivqGGSTITQQLAKNLFLTPERTLT 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 176 RKAREFFLALELTKKYSKAEILTMYLNNSYFGNGVWGVEDASRKYFGTSAANLTVDEAATLAGMLKGPEVYNPYYSVENA 255
Cdd:pfam00912 86 RKLKEAVLALKLERRYSKDEILEAYLNTVYFGRGAYGIEAAARAYFGKDASDLTLAEAALLAGLPQAPSRYNPLRNPERA 165
|
170
....*....|..
gi 2566600597 256 TNRRDTVLAAMV 267
Cdd:pfam00912 166 KRRRNLVLDRMV 177
|
|
| PBP_1c |
TIGR02073 |
penicillin-binding protein 1C; This subfamily of the penicillin binding proteins includes the ... |
79-618 |
4.89e-66 |
|
penicillin-binding protein 1C; This subfamily of the penicillin binding proteins includes the member from E. coli designated penicillin-binding protein 1C. Members have both transglycosylase and transpeptidase domains and are involved in forming cross-links in the late stages of peptidoglycan biosynthesis. All members of this subfamily are presumed to have the same basic function. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273954 [Multi-domain] Cd Length: 727 Bit Score: 232.31 E-value: 4.89e-66
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 79 SDLQSALKTTTTIYDKNKEYAGKLSGQKGTY---VELNAISDHLKNAVIATEDRTFYENNGVN---FKRFFLAVATLGK- 151
Cdd:TIGR02073 2 PPLLFHRPSSTVVLDRHGTLLRALLANDGQWrlpVPLEDISPKFLQALLLYEDKRFYWHPGVNplaLLRAAWQNLTNGRr 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 152 FGGGSTITQQLAKNAYLSQDQTIKRKAREFFLALELTKKYSKAEILTMYLNNSYFGNGVWGVEDASRKYFGTSAANLTVD 231
Cdd:TIGR02073 82 VSGGSTLTMQLARLLDPELSRTLTGKLRQMWRAIQLEARYSKREILEAYLNLAPYGGNLEGLRAASLIYFGKEPSSLSLA 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 232 EAATLAGMLKGPEVYNPYYSVENATNRRDTVLAAMVDAGKLTKSQAKEAASIGMKNR------LADTYAGKIndYR-YPS 304
Cdd:TIGR02073 162 EAALLAALPQAPSARRLDRLPKAAKAARDRLLDRMVEQGPDDSEQVALAALEPLPALpeplpqLAPHFALKL--LRaRPE 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 305 YFDAVVneaidtygisekdivnngykiyTALDQNYQSGMQKTFDDTSlfpvsdyDGQSAQG----ASVALDPKTGGVRGL 380
Cdd:TIGR02073 240 IASVIV----------------------STLDADLQRRLEELARRYL-------SALRPRGisnlAILVVDNRSGAVLAY 290
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 381 VGRVQSTKDAQFRSFNyATQSKRSPASTIKPLvVYSPAIASGW----SIDKELPnkvQDFHGYKPSNYGGIETESIPMYQ 456
Cdd:TIGR02073 291 VGSADFFDDSNSGQVD-GVRAPRSPGSTLKPF-LYALALDDGLlhpdSLLKDVP---LRFGDYAPENFDKTFHGPVPARE 365
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 457 ALANSYNIPAVYTLDKLGINKAFTYGRKFGLN-MSSANKELGVALG-GSVTTNPLEMAQAYSTFANDGIMhrahlitrie 534
Cdd:TIGR02073 366 ALARSLNIPAVRLLERVGPPRFADFLRQAGLNlLKPKSDYYGLSLAlGGAEITLQDLANLYAMLANQGLS---------- 435
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 535 tanGKLVKQFTDKPKRVISR---SVASKMTS-MMLGTFSNGTAINANVY--GYTMAGKTGTTEtDFNpnlsgDQWVVGYT 608
Cdd:TIGR02073 436 ---GPLRFLQTDAKRPERERllsPGAAWIVLdILKDRPRPDDTLPLSALptRLPLAWKTGTSY-GFR-----DAWAAGVS 506
|
570
....*....|
gi 2566600597 609 PDVVISQWVG 618
Cdd:TIGR02073 507 GRYTIGVWVG 516
|
|
| mrcA |
PRK11636 |
penicillin-binding protein 1a; Provisional |
52-645 |
1.74e-63 |
|
penicillin-binding protein 1a; Provisional
Pssm-ID: 183248 [Multi-domain] Cd Length: 850 Bit Score: 227.32 E-value: 1.74e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 52 KLLFIALMAFIL-----IFGSYLFY---LSKTATVSDLQsaLKTTTTIYDKNKEYAGKLSGQKGTYVELNAISDHLKNAV 123
Cdd:PRK11636 5 KYLLILAVCCILlgagsIYGLYRYIepqLPDVATLKDVR--LQTPMQVYSADGELIAQYGEKRRIPLTLDQIPPEMVKAF 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 124 IATEDRTFYENNGVNFKRFFLAVATLGKFG----GGSTITQQLAKNAYLSQDQTIKRKAREFFLALELTKKYSKAEILTM 199
Cdd:PRK11636 83 IATEDSRFYEHHGVDPVGIFRAASVALFSGhasqGASTITQQLARNFFLSPERTLMRKIKEAFLAIRIEQLLTKDEILEL 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 200 YLNNSYFGNGVWGVEDASRKYFGTSAANLTVDEAATLAGMLKGPEVYNPYYSVENATNRRDTVLAAMVDAGKLTKSQAKE 279
Cdd:PRK11636 163 YLNKIYLGYRAYGVGAAAQVYFGKTVDQLTLSEMAVIAGLPKAPSTFNPLYSMDRAVARRNVVLSRMLDEGYITQAQYDQ 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 280 AASIGMknrLADTYAGKInDYRYPSYFDAVVNEAIDTYGiseKDIVNNGYKIYTALDQNYQSGMQKTFDDTslfpVSDYD 359
Cdd:PRK11636 243 ARSEPI---VANYHAPEI-AFSAPYLSEMVRQEMYNRYG---ENAYEDGYRVYTTITRKVQQAAQQAVRNN----VLDYD 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 360 ---------------GQSA------------------------------------------------------------Q 364
Cdd:PRK11636 312 mrhgyrgpanvlwkvGESAwdnkkitdtlkalptygpllpavvtsanpqeatamladgssvalpmegvrwarpyrsdtqQ 391
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 365 GAS-----------------------------------VALDPKTGGVRGLVGRVqstkDAQFRSFNYATQSKRSPASTI 409
Cdd:PRK11636 392 GPTprkvtdvvqtgqqiwvrqvddawwlaqvpdvnsalVSINPQNGAVMALVGGF----DFNQSKFNRATQALRQVGSNI 467
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 410 KPLvVYSPAIASGW---SIDKELPNKVQDFHG---YKPSN----YGGieteSIPMYQALANSYNIPAVYTLDKLGINKAF 479
Cdd:PRK11636 468 KPF-LYTAAMDKGLtlaSMLNDVPISRWDAGAgsdWRPKNsppqYAG----PIRLRQGLGQSKNVVMVRAMRAMGVDYAA 542
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 480 TYGRKFGLNMSSANKELGVALgGSVTTNPLEMAQAYSTFANDGIMHRAHLITRIETANGKLVkqFTDKPKRVIS------ 553
Cdd:PRK11636 543 EYLQRFGFPAQNIVHTESLAL-GSASFTPMQVARGYAVMANGGFLVDPYFISKIENDQGGVI--FEAKPKVACPecdipv 619
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 554 ------RSVASKMTSM--------------------------------------MLGT---FSNGTAINANVYG------ 580
Cdd:PRK11636 620 iygdtqKSNVLENDDVenvatsqeqqnssvpmpqleqanqalvaqngaqeyaphVINTplaFLIKSALNTNIFGepgwmg 699
|
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2566600597 581 -----------YTMAGKTGTTetdfnpNLSGDQWVVGYTPDVVISQWVGFkntDKHHylTDSSAGTASNIFSTQAS 645
Cdd:PRK11636 700 tgwragrdlkrRDIGGKTGTT------NSSKDAWFSGYGPGVVTSVWIGF---DDHR--RDLGRTTASGAIKDQIS 764
|
|
| mrcB |
PRK09506 |
bifunctional glycosyl transferase/transpeptidase; Reviewed |
103-621 |
2.10e-56 |
|
bifunctional glycosyl transferase/transpeptidase; Reviewed
Pssm-ID: 236544 [Multi-domain] Cd Length: 830 Bit Score: 206.54 E-value: 2.10e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 103 SGQKGTYVELNAISDHLKNAVIATEDRTFYENNGVNF---KRFFLAVATLGK-FGGGSTITQQLAKNAYLSQDQTIKRKA 178
Cdd:PRK09506 207 NGEQRLFVPRSGFPDLLVDTLLATEDRHFYEHDGISLysiGRAVLANLTAGRtVQGGSTLTQQLVKNLFLSNERSLWRKA 286
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 179 REFFLALELTKKYSKAEILTMYLNNSYFG----NGVWGVEDASRKYFGTSAANLTVDEAATLAGMLKGPEVYNPYYSVEN 254
Cdd:PRK09506 287 NEAYMALIMDARYSKDRILELYLNEVYLGqsgdDQIRGFPLASLYYFGRPVEELSLDQQALLVGMVKGASLYNPWRNPKL 366
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 255 ATNRRDTVLAAMVDAGKLTKSQAK--EAASIGMKNRladtyAGKINDyrYPSYFDAVVNEAIDTYGISEKDIvnNGYKIY 332
Cdd:PRK09506 367 ALERRNLVLRLLQQQQIIDQELYDmlSARPLGVQPK-----GGVISP--QPAFMQMVRQELQAKLGDKVKDL--SGVKIF 437
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 333 TALDQNYQSGMQKTFDDTSLFPVSDYDGQSAQGASVALDPKTGGVRGLVGrvqsTKDAQFRSFNYATQSKRSPASTIKPl 412
Cdd:PRK09506 438 TTLDPVSQDAAEKAVEEGIPALKKQRKLSDLETAMVVVDRFSGEVRAMVG----GSEPQFAGYNRAMQARRSIGSLAKP- 512
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 413 VVYSPAIA-------SGWSIDKELPNKVQDFHGYKPSNYGGIETESIPMYQALANSYNIPAVY------------TLDKL 473
Cdd:PRK09506 513 ATYLTALSqpdkyrlNTWIADAPISLRQPNGQVWSPQNDDRRFSGRVMLVDALTRSMNVPTVNlgmalglpavtdTWIKL 592
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 474 GINKAFtygrkfgLNMSSAnkelgvALGGSVTTNPLEMAQAYSTFANDGimHRAHL--ITRIETANGKLVKQFTDKPKRV 551
Cdd:PRK09506 593 GVPKDQ-------LNPVPA------MLLGALNLTPIEVAQAFQTIASGG--NRAPLsaLRSVIAEDGKVLYQSFPQAERA 657
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2566600597 552 ISRSVASKMTSMMLGTFSNGTA--INANVYGYTMAGKTGTTetdfnpNLSGDQWVVGYTPDVVISQWVGFKN 621
Cdd:PRK09506 658 VPAQAAYLTLYTMQQVVQRGTGrqLGAKYPNLHLAGKTGTT------NDLVDSWFAGIDGKEVTITWVGRDN 723
|
|
| PRK14850 |
PRK14850 |
penicillin-binding protein 1b; Provisional |
104-624 |
2.92e-56 |
|
penicillin-binding protein 1b; Provisional
Pssm-ID: 237835 [Multi-domain] Cd Length: 764 Bit Score: 205.46 E-value: 2.92e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 104 GQKGTYVELNAISDHLKNAVIATEDRTFYENNGVNFK---RFFLAVATLGK-FGGGSTITQQLAKNAYLSQDQTIKRKAR 179
Cdd:PRK14850 154 GKKRLFIPRNQYPEMLIKTLLAIEDKYFYEHDGIHLSsigRAFLVNLMSGHtIQGGSTLTQQLVKNLFLTNTRSLWRKIN 233
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 180 EFFLALELTKKYSKAEILTMYLNNSYFG-NG---VWGVEDASRKYFGTSAANLTVDEAATLAGMLKGPEVYNPYYSVENA 255
Cdd:PRK14850 234 EIYMALILDRFYSKDRILELYLNEVYLGqDGneqIRGFPLASIYYFGRPINELNLDQYALLVGMVKGASLYNPWTNPNLT 313
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 256 TNRRDTVLAAMVDAGKLTKSQAKEAASigmkNRLADTYAGKINDYRyPSYFDAVVNEAIDTYGISEKDIvnNGYKIYTAL 335
Cdd:PRK14850 314 LKRRNLVLFLLYKQKVITRKLYKDLCS----RPLNVQSKGNIISSH-PAFIQLVCEEFHKKIHYPFKNF--SGTKIFTTL 386
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 336 DQNYQSGMQKTFDDTSLFPVSDYDGQSAQGASVALDPKTGGVRGLVGrvqsTKDAQFRSFNYATQSKRSPASTIKPlVVY 415
Cdd:PRK14850 387 DYISQNAAEQAVKIGIPILKRKKRLKDLEVAMVIIDRFSGEVRALIG----SSKPEFNGYNRALKARRSIGSLSKP-ITY 461
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 416 SPAIA-------SGWSIDKELPNKVQDFHGYKPSNYGGIETESIPMYQALANSYNIPAVYTLDKLGINKAFTYGRKFGLN 488
Cdd:PRK14850 462 LTALSqpekyhlNTWISDTPISIKLDNGQYWTPKNNNFSFSGKVMLIDALIHSINIPTVHLSINLGLKKLVDSWILLGIS 541
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 489 MSSANKELGVALgGSVTTNPLEMAQAYSTFANDGIMHRAHLITRIETANGKLVKQFTDKPKRVISRSVASKMTSMMLGTF 568
Cdd:PRK14850 542 SNYITPLPSISL-GAINLTPMEVAQVFQIIGSGGYKSSLSSIRSIISDDNKVLYQNFPQSKHVESSQASYLTLYAMQQVV 620
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*...
gi 2566600597 569 SNGTAINANVY--GYTMAGKTGTTetdfnpNLSGDQWVVGYTPDVVISQWVGFKNTDK 624
Cdd:PRK14850 621 KSGTAKSLGTIfkEFSLAGKTGTT------NNLVDSWFVGIDGKQVVITWIGRDNNHT 672
|
|
| FtsI |
COG0768 |
Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell ... |
327-609 |
1.44e-41 |
|
Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell cycle control, cell division, chromosome partitioning, Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440531 [Multi-domain] Cd Length: 568 Bit Score: 159.99 E-value: 1.44e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 327 NGYKIYTALDQNYQSGMQKTFDDTslfpVSDYDGQSaqGASVALDPKTGGVRGLVGR-------VQSTKDAQFRsfNYAT 399
Cdd:COG0768 217 PGKDLVLTIDSDLQKIAEEALKKA----VEEYKAKS--GAVVVMDPKTGEILAMASYpsfdpnlFVGGPDEPLR--NRAV 288
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 400 QSKRSPASTIKPLVVYSpAIASGwSIDKE----------LPNKVqdFHGYKPSNYGgieteSIPMYQALANSYNIPAVYT 469
Cdd:COG0768 289 QGTYEPGSTFKPFTAAA-ALEEG-VITPDttfdcpgyyrVGGRT--IRDWDRGGHG-----TLTLTEALAKSSNVGFYKL 359
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 470 LDKLGINKAFTYGRKFGLNmssanKELGVALGG------------------------SVTTNPLEMAQAYSTFANDGIMH 525
Cdd:COG0768 360 ALRLGIDKLYDYLKKFGLG-----QKTGIDLPGeasgllpspkrwypgetatmsigqGLSVTPLQLAQAYAAIANGGVLV 434
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 526 RAHLITRIETANGKLVKQFTDKPKRVISRSVASKMTSMMLGTFSN--GTAINANVYGYTMAGKTGTTETdFNPNLSGDQ- 602
Cdd:COG0768 435 KPHLVKEIVDPDGEVVKEEPEVLRRVISPETAETVREGMEGVVNEpgGTARRAAIPGYRVAGKTGTAQV-VDIGNGGYYk 513
|
330
....*....|..
gi 2566600597 603 -----WVVGYTP 609
Cdd:COG0768 514 grhiaSFVGFAP 525
|
|
| PRK13481 |
PRK13481 |
glycosyltransferase; Provisional |
52-282 |
3.00e-37 |
|
glycosyltransferase; Provisional
Pssm-ID: 184078 [Multi-domain] Cd Length: 232 Bit Score: 139.17 E-value: 3.00e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 52 KLLFIALMAFILIFGsYLFYLSKTATVSDLQSAlkttttiydknkeyagklsGQKGTYVELNAISDHLKNAVIATEDRTF 131
Cdd:PRK13481 10 KILLTILIIIALFIG-IMYFLSTRDNVDELRKI-------------------ENKSSFVSADNMPEYVKGAFISMEDERF 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 132 YENNGVNFKRFFLAV-ATLG--KFGGGSTITQQLAKNAYLSQDQTIKRKAREFFLALELTKKYSKAEILTMYLNNSYFGN 208
Cdd:PRK13481 70 YKHHGFDLKGTTRALfSTISdrDVQGGSTITQQVVKNYFYDNERSFTRKVKELFVAHRVEKQYSKNEILSFYLNNIYFGD 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 209 GVWGVEDASRKYFGTSA-------ANLTVDEAATLAGMLKGPEVYNPYYSVENATNRRDTVLAAMVDAGKLTKSQAKEAA 281
Cdd:PRK13481 150 NQYTLEGAANHYFGTTVnknsttmSHITVLQSAILASKVNAPSVYNINDMSENFTQRVSTNLEKMKQQNYINETQYQQAM 229
|
.
gi 2566600597 282 S 282
Cdd:PRK13481 230 S 230
|
|
| mono_pep_trsgly |
TIGR02070 |
monofunctional biosynthetic peptidoglycan transglycosylase; This family is one of the ... |
109-246 |
7.67e-33 |
|
monofunctional biosynthetic peptidoglycan transglycosylase; This family is one of the transglycosylases involved in the late stages of peptidoglycan biosynthesis. Members tend to be small, about 240 amino acids in length, and consist almost entirely of a domain described by pfam00912 for transglycosylases. Species with this protein will have several other transglycosylases as well. All species with this protein are Proteobacteria that produce murein (peptidoglycan). [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273951 [Multi-domain] Cd Length: 224 Bit Score: 126.42 E-value: 7.67e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 109 YVELNAISDHLKNAVIATEDRTFYENNGVNFKRFFLAVATLGKFG----GGSTITQQLAKNAYLSQDQTIKRKAREFFLA 184
Cdd:TIGR02070 57 WRPYDQISPNLKRAVIASEDAKFVEHHGFDWEAIQDALEKNEKSGkvvrGGSTISQQLAKNLFLWSGRSYLRKGLEAWAT 136
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2566600597 185 LELTKKYSKAEILTMYLNNSYFGNGVWGVEDASRKYFGTSAANLTVDEAATLAGMLKGPEVY 246
Cdd:TIGR02070 137 WMLETWWSKQRILEVYLNSVEWGNGVFGAEAAARYYFKRSASNLTRGQAARLAAVLPNPKYY 198
|
|
| PRK11240 |
PRK11240 |
penicillin-binding protein 1C; Provisional |
110-618 |
2.86e-32 |
|
penicillin-binding protein 1C; Provisional
Pssm-ID: 183049 [Multi-domain] Cd Length: 772 Bit Score: 133.67 E-value: 2.86e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 110 VELNAISDHLKNAVIATEDRTFYENNGVNfkRFFLAVA-----TLGK-FGGGSTITQQLAKnayL--SQDQTIKRKAREF 181
Cdd:PRK11240 65 VTIEDVSPRYLEALINYEDRWFWKHPGVN--PFSVARAawqdlTSGRvISGGSTLTMQVAR---LldPHPRTFGGKIRQL 139
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 182 FLALELTKKYSKAEILTMYLNNSYFGNGVWGVEDASRKYFGTSAANLTVDEAATLAGMLKGPEVYNPYYSVENATNRRDT 261
Cdd:PRK11240 140 WRALQLEWHLSKREILTLYLNRAPFGGTLQGIGAASWAYLGKSPANLSYAEAALLAVLPQAPSRLRPDRWPERAEAARNK 219
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 262 VLAAMVDAGKLTKSQAKEAAS--IGMKNR----LADTYAGKINDYRYPSyfdavvneaidtygisekdivnngyKIYTAL 335
Cdd:PRK11240 220 VLERMAEQGVWSAEQVKESREepVWLAPRqmpqLAPLFARMMLGKSKSD-------------------------KIVTTL 274
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 336 DqnyqSGMQKTFDDTSLfpvsDYDGQSAQGASVAL---DPKTGGVRGLVGRVQSTKDAQFRSFNYATqSKRSPASTIKPL 412
Cdd:PRK11240 275 D----AGLQRRLEDLAL----NWKGRLPPRSSLAMivvDHTDMAVRGWVGSVDLNDDSRFGHVDMVN-AIRSPGSVLKPF 345
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 413 vVYSPAIASGW----SIDKELPNKVQDfhgYKPSNYGGIETESIPMYQALANSYNIPAVYTLDKLGiNKAFTYG-RKFGL 487
Cdd:PRK11240 346 -VYGLALDDGLihpaSLLQDVPRRTGD---YRPGNFDSGFHGPVSMSEALVRSLNLPAVQVLEAYG-PKRFAAKlRNVGL 420
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 488 NM---SSANKELGVALGGsvTTNPLE-MAQAYSTFANDGimhrahlitriETANGKLVKQFTDKPKRVISRSVASKMTSM 563
Cdd:PRK11240 421 PLylpAGAEPNLSLILGG--AGARLEdMVAAYSAFARHG-----------KAAKLRLQPDDPLLERPLMSPGAAWIIRRI 487
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*..
gi 2566600597 564 MLGTfSNGTAINANVYGYTMAGKTGTTetdfnpnlSG--DQWVVGYTPDVVISQWVG 618
Cdd:PRK11240 488 MADE-AQPLPDAALPRVVPLAWKTGTS--------YGyrDAWAIGVNARYVIGIWTG 535
|
|
| Transpeptidase |
pfam00905 |
Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss: ... |
365-610 |
5.36e-30 |
|
Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss:P14677) is conserved in all members of this family.
Pssm-ID: 425939 [Multi-domain] Cd Length: 296 Bit Score: 120.21 E-value: 5.36e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 365 GASVALDPKTGGVRGLVGRVQSTKDAQFRSF-NYATQSKRSPASTIKPLVVySPAIASG-WSIDKELpnKVQDFHGYKPS 442
Cdd:pfam00905 1 GSAVVLDPKTGEVLAMVGKPSYDPNGFIGPLrNRAVTSRYEPGSTFKPFTA-LAALDNGvLKPDETI--FDWPGKQQGGK 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 443 NYGG---IETESIPMYQALANSYNIPAVYTLDKLGINKAFTYGRKFGLNMSSANKELG---------------VALGGSV 504
Cdd:pfam00905 78 SIGDwnqDQVGIGTLRQALEYSSNWYMQKLAQKLGADKLRSYLKKFGYGNKTGIGLPGenagyltpywlegatASFGIGL 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 505 TTNPLEMAQAYSTFANDGIMHRAHLITRIETAngklvKQFTDKPKRVISRSVASKMTSMMLGTFSNGTAIN-ANVYGYTM 583
Cdd:pfam00905 158 TITPLQQAQAYAAIANGGKLVPPHLVKSIEDK-----VDPKVLNKLPISKSTAEKVKDMLRLVVNDGTGTGtAAVPGYKV 232
|
250 260 270
....*....|....*....|....*....|...
gi 2566600597 584 AGKTGTTETdFNPNLSGDQ------WVVGYTPD 610
Cdd:pfam00905 233 AGKTGTAQV-AGPKGGGYYdgaqigWFVGYAPA 264
|
|
| pbp2_mrdA |
TIGR03423 |
penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 ... |
328-609 |
2.30e-27 |
|
penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 (PBP-2), a protein whose gene (designated pbpA or mrdA) generally is found next to the gene for RodA, a protein required for rod (bacillus) shape in many bacteria. PBP-2 acts as a transpeptidase for cell elongation (hence, rod-shape). [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 274573 [Multi-domain] Cd Length: 592 Bit Score: 117.62 E-value: 2.30e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 328 GYKIYTALDQNYQSGMQKTFDDTSlfpvsdydgqsaqGASVALDPKTGGVRGLVGR--------VQ--STKD-AQFRS-- 394
Cdd:TIGR03423 225 GKDLVLTIDARLQQAAEKALGGRR-------------GAVVVMDPRTGEILAMVSTpsfdpnlfVDgiSSKDyKALLNdp 291
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 395 ----FNYATQSKRSPASTIKPlVVYSPAIASGwSIDKE----------LPNKVqdFHGYKPSNYGgieteSIPMYQALAN 460
Cdd:TIGR03423 292 drplLNRAIQGVYPPGSTFKP-VVALAALEEG-VITPEtriycpgyfqLGGRR--FRCWKRGGHG-----RVDLRKAIEE 362
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 461 SYNIPAvYTL-DKLGINKAFTYGRKFGL--------------NM-SSANKE------------LGVALG-GSVTTNPLEM 511
Cdd:TIGR03423 363 SCDVYF-YQLaLRLGIDKIAEYAKRFGFgqktgidlpgeksgLVpSREWKRkrfgqpwypgdtLNVSIGqGYVLVTPLQL 441
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2566600597 512 AQAYSTFANDGIMHRAHLITRIETANGKLVKQFTDKPKRV--ISRSVASKMTSMMLG--TFSNGTAINANVY-GYTMAGK 586
Cdd:TIGR03423 442 AVATAALANGGKLYKPHLVKSIEDPDGGVVRRTEPEVLRPlpISPENLDVVREGMRDvvNGPGGTARRARLGlPYKMAGK 521
|
330 340 350
....*....|....*....|....*....|....*...
gi 2566600597 587 TGTTETdfnPNLSGDQ---------------WVVGYTP 609
Cdd:TIGR03423 522 TGTAQV---VSLKQGEkydaeqiperlrdhaLFVAFAP 556
|
|
| |
