|
Name |
Accession |
Description |
Interval |
E-value |
| RssA |
COG1752 |
Predicted acylesterase/phospholipase RssA, containd patatin domain [General function ... |
38-326 |
1.35e-88 |
|
Predicted acylesterase/phospholipase RssA, containd patatin domain [General function prediction only];
Pssm-ID: 441358 [Multi-domain] Cd Length: 261 Bit Score: 278.71 E-value: 1.35e-88
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2578669560 38 PAQRPRIGLVLGGGGARGSAHVGVLKVLEELHIPIDYIAGNSMGAIVGGLYAAGFTPDEIGHELKTIDWDDTFIDQPPRT 117
Cdd:COG1752 1 APARPKIGLVLSGGGARGAAHIGVLKALEEAGIPPDVIAGTSAGAIVGALYAAGYSADELEELWRSLDRRDLFDLSLPRR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2578669560 118 DRSFRRKLddnlymvkpklgfsddgevkTPLAYIHGQKFDLQLSRLTLRatdiHDFNKLPIPFHAVATDLETGQAVVLQS 197
Cdd:COG1752 81 LLRLDLGL--------------------SPGGLLDGDPLRRLLERLLGD----RDFEDLPIPLAVVATDLETGREVVFDS 136
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2578669560 198 GDLARAIRASMAVPGAFDPVEIDGRLLVDGLVANNVPVNVARDMGADILIVVDVGSglyKREDIKGALDVVAQLTNILSE 277
Cdd:COG1752 137 GPLADAVRASAAIPGVFPPVEIDGRLYVDGGVVNNLPVDPARALGADRVIAVDLNP---PLRKLPSLLDILGRALEIMFN 213
|
250 260 270 280
....*....|....*....|....*....|....*....|....*....
gi 2578669560 278 RNVEQQLAtLKPTDILIKPQLGDLGSGDFQRAGEGIVIGEAAARGQLDA 326
Cdd:COG1752 214 SILRRELA-LEPADILIEPDLSGISLLDFSRAEELIEAGYEAARRALDE 261
|
|
| Pat_PNPLA6_PNPLA7_NTE1_like |
cd07205 |
Patatin-like phospholipase domain containing protein 6, protein 7, and fungal NTE1; ... |
44-251 |
1.10e-61 |
|
Patatin-like phospholipase domain containing protein 6, protein 7, and fungal NTE1; Patatin-like phospholipase domain containing protein 6 (PNPLA6) and protein 7 (PNPLA7) are included in this family. PNPLA6 is commonly known as Neuropathy Target Esterase (NTE). NTE has at least two functional domains: the N-terminal domain putatively regulatory domain and the C-terminal catalytic domain which shows esterase activity. NTE shows phospholipase activity for lysophosphatidylcholine (LPC) and phosphatidylcholine (PC). Exposure of NTE to organophosphates leads to organophosphate-induced delayed neurotoxicity (OPIDN). OPIDN is a progressive neurological condition that is characterized by weakness, paralysis, pain, and paresthesia. PNPLA7 is an insulin-regulated phospholipase that is homologus to Neuropathy Target Esterase (NTE or PNPLA6) and is also known as NTE-related esterase (NRE). Human NRE is predominantly expressed in prostate, white adipose, and pancreatic tissue. NRE hydrolyzes sn-1 esters in lysophosphatidylcholine and lysophosphatidic acid, but shows no lipase activity with substrates like triacylglycerols (TG), cholesteryl esters, retinyl esters (RE), phosphatidylcholine (PC), or monoacylglycerol (MG). This family includes subfamily of PNPLA6 (NTE) and PNPLA7 (NRE)-like phospholipases.
Pssm-ID: 132844 [Multi-domain] Cd Length: 175 Bit Score: 204.32 E-value: 1.10e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2578669560 44 IGLVLGGGGARGSAHVGVLKVLEELHIPIDYIAGNSMGAIVGGLYAAGFTPDEIGHELKTIdwddtfidqppRTDRSFRR 123
Cdd:cd07205 1 IGLALSGGGARGLAHIGVLKALEEAGIPIDIVSGTSAGAIVGALYAAGYSPEEIEERAKLR-----------STDLKALS 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2578669560 124 KLddnlymVKPKLGFSDdgevktplayihGQKFDlqlsRLTLRATDIHDFNKLPIPFHAVATDLETGQAVVLQSGDLARA 203
Cdd:cd07205 70 DL------TIPTAGLLR------------GDKFL----ELLDEYFGDRDIEDLWIPFFIVATDLTSGKLVVFRSGSLVRA 127
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 2578669560 204 IRASMAVPGAFDPVEIDGRLLVDGLVANNVPVNVARDMGADILIVVDV 251
Cdd:cd07205 128 VRASMSIPGIFPPVKIDGQLLVDGGVLNNLPVDVLRELGADIIIAVDL 175
|
|
| BamA |
COG4775 |
Outer membrane protein assembly factor BamA [Cell wall/membrane/envelope biogenesis]; |
345-738 |
9.89e-51 |
|
Outer membrane protein assembly factor BamA [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 443807 [Multi-domain] Cd Length: 711 Bit Score: 189.15 E-value: 9.89e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2578669560 345 VPDKLPIIDFVRLDNQSRIGDTVILSRISLKPGQALNSAQLDKEINEIYGLDVFESVRYEVVDEGGKTG---LVLHAKEK 421
Cdd:COG4775 307 DEGPRVYVDRIEIEGNTRTRDEVIRRELRLKEGDPFSREKLERSRRRLYRLGYFESVDVETEPGPSTPDqvdLVVDVKEK 386
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2578669560 422 SWGPnyLQFGMELASDFNnestYNLGVLYTRTAINALNGEIRLGLQIGQD-PTVAAEWYQPldpasrYFINTRVALASNQ 500
Cdd:COG4775 387 PTGS--LSLGAGYSSDDG----FIGGASLSQRNLLGTGQELSLSLQLGSYsQSYSLSFTEP------YFFGSPLSLGVSL 454
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2578669560 501 FNVYAGNDAIAQYDVSRAVLDLGLGREFGTWGQARIGYLWSEGDVDMVIGPPSL----EGDFQIGQLYAQLAVDTLDSVY 576
Cdd:COG4775 455 FYRRRDASDYSSYDLKRTGGGLGLGYPLSEDLRLSLGYGYERTDISDVDSSPDYlpdqNGSSNTSSLGLGLTYDTRDNPL 534
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2578669560 577 FPGSGRKGGVSLIASQEALGADEDFNQVLLSYTEAFS-SGRHHLIGAFRFDTT--LDDDAPLESLFRAGGFLHLSGYRPN 653
Cdd:COG4775 535 FPTRGSYLSLSLEFAGPYLGGDLEYYKLSADARYYFPlGKKLVLALRAEAGYLggYGKDLPFFERFYLGGFGSLRGYEEN 614
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2578669560 654 QLS----GQQVGIASLVYYRRILDARILPGYVGASIEFGNAWQNSSDVSFSSGLFNGSVFFGADTPIGPLYLGVGFA--- 726
Cdd:COG4775 615 SLGprlgGNAYLLGSAELRFPLPLPPSAGLRGALFVDAGNVWDSGDDFDLSDLRYSAGVGLRWDTPLGPLRLDYAYPldk 694
|
410
....*....|..
gi 2578669560 727 EGGTGTAFLHLG 738
Cdd:COG4775 695 EPGDSGQRFHFS 706
|
|
| PRK10279 |
PRK10279 |
patatin-like phospholipase RssA; |
40-327 |
1.35e-37 |
|
patatin-like phospholipase RssA;
Pssm-ID: 182352 [Multi-domain] Cd Length: 300 Bit Score: 142.54 E-value: 1.35e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2578669560 40 QRPRIGLVLGGGGARGSAHVGVLKVLEELHIPIDYIAGNSMGAIVGGLYAAgftpdeigHELKTID-WDDTF--IDQPPR 116
Cdd:PRK10279 2 RKIKIGLALGSGAARGWSHIGVINALKKVGIEIDIVAGCSIGSLVGAAYAC--------DRLSALEdWVTSFsyWDVLRL 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2578669560 117 TDRSFRRKlddnlymvkpklgfsddgevktplAYIHGQKFDLQLSRLtLRATDIHDFNklpIPFHAVATDLETGQAVVLQ 196
Cdd:PRK10279 74 MDLSWQRG------------------------GLLRGERVFNQYREI-MPETEIENCS---RRFGAVATNLSTGRELWFT 125
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2578669560 197 SGDLARAIRASMAVPGAFDPVEIDGRLLVDGLVANNVPVNVARDMGADILIVVDV-----------------------GS 253
Cdd:PRK10279 126 EGDLHLAIRASCSMPGLMAPVAHNGYWLVDGAVVNPVPVSLTRALGADIVIAVDLqhdahlmqqdllsfnvseensenGD 205
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2578669560 254 GLYKREDIK---------------GALDVVAQLTNILSERNVEQQLATlKPTDILIKPQLGDLGSGDFQRAGEGIVIGEA 318
Cdd:PRK10279 206 SLPWHARLKerlgsittrravtapTAMEIMTTSIQVLENRLKRNRMAG-DPPDILIQPVCPQISTLDFHRAHAAIAAGQL 284
|
....*....
gi 2578669560 319 AARGQLDAL 327
Cdd:PRK10279 285 AVEKKMDEL 293
|
|
| Patatin |
pfam01734 |
Patatin-like phospholipase; This family consists of various patatin glycoproteins from plants. ... |
46-238 |
1.14e-30 |
|
Patatin-like phospholipase; This family consists of various patatin glycoproteins from plants. The patatin protein accounts for up to 40% of the total soluble protein in potato tubers. Patatin is a storage protein but it also has the enzymatic activity of lipid acyl hydrolase, catalysing the cleavage of fatty acids from membrane lipids. Members of this family have been found also in vertebrates.
Pssm-ID: 396341 Cd Length: 190 Bit Score: 119.25 E-value: 1.14e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2578669560 46 LVLGGGGARGSAHVGVLKVLEELHIPIDYIAGNSMGAIVGGLYAAGFTPDEIGHELKTIdWDDTFIDQPprtdRSFRRKL 125
Cdd:pfam01734 1 LVLSGGGARGAYHLGVLKALGEAGIRFDVISGTSAGAINAALLALGRDPEEIEDLLLEL-DLNLFLSLI----RKRALSL 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2578669560 126 DDNLYMVKPKLGFSDDGEVKTPLAYIHGqkfDLQLSRLT--LRATDIHDFNKLPIPFHAVATDLETGQAVVLQS--GDLA 201
Cdd:pfam01734 76 LALLRGLIGEGGLFDGDALRELLRKLLG---DLTLEELAarLSLLLVVALRALLTVISTALGTRARILLPDDLDddEDLA 152
|
170 180 190
....*....|....*....|....*....|....*..
gi 2578669560 202 RAIRASMAVPGAFDPVEIDGRLLVDGLVANNVPVNVA 238
Cdd:pfam01734 153 DAVLASSALPGVFPPVRLDGELYVDGGLVDNVPVEAA 189
|
|
| OM_YaeT |
TIGR03303 |
outer membrane protein assembly complex, YaeT protein; Members of this protein family are the ... |
361-726 |
1.31e-09 |
|
outer membrane protein assembly complex, YaeT protein; Members of this protein family are the YaeT protein of the YaeT/YfiO complex for assembling proteins into the outer membrane of Gram-negative bacteria. This protein is similar in sequence and function to a non-essential paralog, YtfM, that is also in the Omp85 family. Members of this family typically have five tandem copies of the surface antigen variable number repeat (pfam07244), followed by an outer membrane beta-barrel domain (pfam01103), while the YtfM family typically has a single pfam07244 repeat. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 274514 [Multi-domain] Cd Length: 741 Bit Score: 61.44 E-value: 1.31e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2578669560 361 SRIGDTVILSRISLKPGQALNSAQLDKEINEIYGLDVFESVRYEV--VDEGGKTGLVLHAKEKSWGPnyLQFGMelasDF 438
Cdd:TIGR03303 333 TRTRDEVIRRELRQLEGDWYSLSKIKRSKRRLERLGYFETVNIETvpVGSPDQVDLNVKVKEQPTGS--ISFGV----GY 406
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2578669560 439 NNESTYNLGVlytrtAINALN--G---EIRLGLQIGQDPTVAAEWYQplDPasrYFINTRVALASNQF-NVYAGNDA-IA 511
Cdd:TIGR03303 407 GSSSGLSFNA-----SISERNflGtgnRLSLSANKSSLSTSYSLSFT--DP---YFTDDGVSLGFSIFySETDRNYKnFS 476
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2578669560 512 QYDVSRAVLDLGLGREFGTWGQARIGYLWSEGDVDMVIGPPS--------LEGDFQIGQLYAQLAVDTLDSVYFPgsgrK 583
Cdd:TIGR03303 477 DYKTKTYGGSINLGYPITEYLRVSLGYGYEQNKIKDDSDSDSsasyfikeQGGKFIDSSLSYGWSYDTLDSGYFP----T 552
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2578669560 584 GGVSLIASQEA--LGADEDFNQVLLSYTEAFS-SGRHHLIGAFRFDTTL-----DDDAPLESLFRAGGFLHLSGYRPNQL 655
Cdd:TIGR03303 553 KGSIQRLSQEFagPGGDLKYYKLTYDSEYYIPlSKEDDWVLSLRGRLGYgngygGKDLPFYERFYAGGIGSVRGFESNGI 632
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2578669560 656 SGQQVGiaslvyyrriLDARILPG--YVGASIE---------------------FGNAWQNSSDVSFSSGLFNG---SVF 709
Cdd:TIGR03303 633 GPRDIN----------DSGDSIGGnaMATANVElifplpflpednglrgsvffdAGNVWGTDQKKEGDYSDDSSlraSVG 702
|
410
....*....|....*....
gi 2578669560 710 FGAD--TPIGPLYLGVGFA 726
Cdd:TIGR03303 703 VGLRwiSPMGPLRFSYAKP 721
|
|
| Omp85 |
pfam01103 |
Omp85 superfamily domain; The Omp85 protein superfamily contains bacterial outer membrane ... |
462-725 |
1.80e-08 |
|
Omp85 superfamily domain; The Omp85 protein superfamily contains bacterial outer membrane proteins, which can function as protein translocases or as membrane protein assembly factors. The family includes the membrane bound beta barrel of proteins such as BamA and TamA from E. coli.
Pssm-ID: 460065 [Multi-domain] Cd Length: 319 Bit Score: 56.60 E-value: 1.80e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2578669560 462 IRLGLQIGQDPT-VAAEWYQPldpasrYFINTRVALAsnqFNVYAGN-----DAIAQYDVSRAVLDLGLGREFGTWGQAR 535
Cdd:pfam01103 9 LSVNASRGSYETsFSLSFTDP------YFLGDGVSLG---GSLFYNSydsdrDSSDSYRITTYGFSVSLGRPITENWSLS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2578669560 536 IGYLWSEGDVD--------MVIGPPSLE-GDFQIGQLYAQLAVDTLDSVYFPGSGRKGGVSLIASQEALGADEDFNQVLL 606
Cdd:pfam01103 80 LGLGYQHNKILdesgspniRNYYPSASGtGKSLTFSLSYGWTYDTRDDGLFPTRGSYLKFNLEFTGPFLGGDVSYYKLTA 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2578669560 607 SYTEAFS-SGRHHLIGAFRF-----DTTLDDDAPLESLFRAGGFLHLSGYR-----PNQLSGQQVG-----IASLVYYRR 670
Cdd:pfam01103 160 DGSYYYPlGKDDSFVLSARValgylDGYGTKDLPFYERFYAGGSNSVRGFEyggigPRDEDGDALGgnsyvVASLELRFP 239
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2578669560 671 ILDARILPGYVGASIEFGNAWQNSSDVSFSSGLFNGSVFFGA--------DTPIGPLYLGVGF 725
Cdd:pfam01103 240 LPFVPKQSVRGVLFFDAGNVWNTGSTDPGSSRGARSKAGIRAsvgvglrwLSPLGPLRFDYAF 302
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| RssA |
COG1752 |
Predicted acylesterase/phospholipase RssA, containd patatin domain [General function ... |
38-326 |
1.35e-88 |
|
Predicted acylesterase/phospholipase RssA, containd patatin domain [General function prediction only];
Pssm-ID: 441358 [Multi-domain] Cd Length: 261 Bit Score: 278.71 E-value: 1.35e-88
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2578669560 38 PAQRPRIGLVLGGGGARGSAHVGVLKVLEELHIPIDYIAGNSMGAIVGGLYAAGFTPDEIGHELKTIDWDDTFIDQPPRT 117
Cdd:COG1752 1 APARPKIGLVLSGGGARGAAHIGVLKALEEAGIPPDVIAGTSAGAIVGALYAAGYSADELEELWRSLDRRDLFDLSLPRR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2578669560 118 DRSFRRKLddnlymvkpklgfsddgevkTPLAYIHGQKFDLQLSRLTLRatdiHDFNKLPIPFHAVATDLETGQAVVLQS 197
Cdd:COG1752 81 LLRLDLGL--------------------SPGGLLDGDPLRRLLERLLGD----RDFEDLPIPLAVVATDLETGREVVFDS 136
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2578669560 198 GDLARAIRASMAVPGAFDPVEIDGRLLVDGLVANNVPVNVARDMGADILIVVDVGSglyKREDIKGALDVVAQLTNILSE 277
Cdd:COG1752 137 GPLADAVRASAAIPGVFPPVEIDGRLYVDGGVVNNLPVDPARALGADRVIAVDLNP---PLRKLPSLLDILGRALEIMFN 213
|
250 260 270 280
....*....|....*....|....*....|....*....|....*....
gi 2578669560 278 RNVEQQLAtLKPTDILIKPQLGDLGSGDFQRAGEGIVIGEAAARGQLDA 326
Cdd:COG1752 214 SILRRELA-LEPADILIEPDLSGISLLDFSRAEELIEAGYEAARRALDE 261
|
|
| Pat_PNPLA6_PNPLA7_NTE1_like |
cd07205 |
Patatin-like phospholipase domain containing protein 6, protein 7, and fungal NTE1; ... |
44-251 |
1.10e-61 |
|
Patatin-like phospholipase domain containing protein 6, protein 7, and fungal NTE1; Patatin-like phospholipase domain containing protein 6 (PNPLA6) and protein 7 (PNPLA7) are included in this family. PNPLA6 is commonly known as Neuropathy Target Esterase (NTE). NTE has at least two functional domains: the N-terminal domain putatively regulatory domain and the C-terminal catalytic domain which shows esterase activity. NTE shows phospholipase activity for lysophosphatidylcholine (LPC) and phosphatidylcholine (PC). Exposure of NTE to organophosphates leads to organophosphate-induced delayed neurotoxicity (OPIDN). OPIDN is a progressive neurological condition that is characterized by weakness, paralysis, pain, and paresthesia. PNPLA7 is an insulin-regulated phospholipase that is homologus to Neuropathy Target Esterase (NTE or PNPLA6) and is also known as NTE-related esterase (NRE). Human NRE is predominantly expressed in prostate, white adipose, and pancreatic tissue. NRE hydrolyzes sn-1 esters in lysophosphatidylcholine and lysophosphatidic acid, but shows no lipase activity with substrates like triacylglycerols (TG), cholesteryl esters, retinyl esters (RE), phosphatidylcholine (PC), or monoacylglycerol (MG). This family includes subfamily of PNPLA6 (NTE) and PNPLA7 (NRE)-like phospholipases.
Pssm-ID: 132844 [Multi-domain] Cd Length: 175 Bit Score: 204.32 E-value: 1.10e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2578669560 44 IGLVLGGGGARGSAHVGVLKVLEELHIPIDYIAGNSMGAIVGGLYAAGFTPDEIGHELKTIdwddtfidqppRTDRSFRR 123
Cdd:cd07205 1 IGLALSGGGARGLAHIGVLKALEEAGIPIDIVSGTSAGAIVGALYAAGYSPEEIEERAKLR-----------STDLKALS 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2578669560 124 KLddnlymVKPKLGFSDdgevktplayihGQKFDlqlsRLTLRATDIHDFNKLPIPFHAVATDLETGQAVVLQSGDLARA 203
Cdd:cd07205 70 DL------TIPTAGLLR------------GDKFL----ELLDEYFGDRDIEDLWIPFFIVATDLTSGKLVVFRSGSLVRA 127
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 2578669560 204 IRASMAVPGAFDPVEIDGRLLVDGLVANNVPVNVARDMGADILIVVDV 251
Cdd:cd07205 128 VRASMSIPGIFPPVKIDGQLLVDGGVLNNLPVDVLRELGADIIIAVDL 175
|
|
| Pat_NTE_like_bacteria |
cd07228 |
Bacterial patatin-like phospholipase domain containing protein 6; Bacterial patatin-like ... |
44-251 |
6.33e-57 |
|
Bacterial patatin-like phospholipase domain containing protein 6; Bacterial patatin-like phospholipase domain containing protein 6. PNPLA6 is commonly known as Neuropathy Target Esterase (NTE). NTE has at least two functional domains: the N-terminal domain putatively regulatory domain and the C-terminal catalytic domain which shows esterase activity. NTE shows phospholipase activity for lysophosphatidylcholine (LPC) and phosphatidylcholine (PC). Exposure of NTE to organophosphates leads to organophosphate-induced delayed neurotoxicity (OPIDN). OPIDN is a progressive neurological condition that is characterized by weakness, paralysis, pain, and paresthesia. This group includes YCHK and rssA from Escherichia coli as well as Ylbk from Bacillus amyloliquefaciens.
Pssm-ID: 132866 [Multi-domain] Cd Length: 175 Bit Score: 191.72 E-value: 6.33e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2578669560 44 IGLVLGGGGARGSAHVGVLKVLEELHIPIDYIAGNSMGAIVGGLYAAGFTPDEIgHELKTIDWddtfidqpprtdRSFRR 123
Cdd:cd07228 1 IGLALGSGGARGWAHIGVLRALEEEGIEIDIIAGSSIGALVGALYAAGHLDALE-EWVRSLSQ------------RDVLR 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2578669560 124 KLDdnlyMVKPKLGFsddgevktplayIHGQKFDLQLSRLTLRATdihdFNKLPIPFHAVATDLETGQAVVLQSGDLARA 203
Cdd:cd07228 68 LLD----LSASRSGL------------LKGEKVLEYLREIMGGVT----IEELPIPFAAVATDLQTGKEVWFREGSLIDA 127
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 2578669560 204 IRASMAVPGAFDPVEIDGRLLVDGLVANNVPVNVARDMGADILIVVDV 251
Cdd:cd07228 128 IRASISIPGIFAPVEHNGRLLVDGGVVNPIPVSVARALGADIVIAVDL 175
|
|
| BamA |
COG4775 |
Outer membrane protein assembly factor BamA [Cell wall/membrane/envelope biogenesis]; |
345-738 |
9.89e-51 |
|
Outer membrane protein assembly factor BamA [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 443807 [Multi-domain] Cd Length: 711 Bit Score: 189.15 E-value: 9.89e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2578669560 345 VPDKLPIIDFVRLDNQSRIGDTVILSRISLKPGQALNSAQLDKEINEIYGLDVFESVRYEVVDEGGKTG---LVLHAKEK 421
Cdd:COG4775 307 DEGPRVYVDRIEIEGNTRTRDEVIRRELRLKEGDPFSREKLERSRRRLYRLGYFESVDVETEPGPSTPDqvdLVVDVKEK 386
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2578669560 422 SWGPnyLQFGMELASDFNnestYNLGVLYTRTAINALNGEIRLGLQIGQD-PTVAAEWYQPldpasrYFINTRVALASNQ 500
Cdd:COG4775 387 PTGS--LSLGAGYSSDDG----FIGGASLSQRNLLGTGQELSLSLQLGSYsQSYSLSFTEP------YFFGSPLSLGVSL 454
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2578669560 501 FNVYAGNDAIAQYDVSRAVLDLGLGREFGTWGQARIGYLWSEGDVDMVIGPPSL----EGDFQIGQLYAQLAVDTLDSVY 576
Cdd:COG4775 455 FYRRRDASDYSSYDLKRTGGGLGLGYPLSEDLRLSLGYGYERTDISDVDSSPDYlpdqNGSSNTSSLGLGLTYDTRDNPL 534
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2578669560 577 FPGSGRKGGVSLIASQEALGADEDFNQVLLSYTEAFS-SGRHHLIGAFRFDTT--LDDDAPLESLFRAGGFLHLSGYRPN 653
Cdd:COG4775 535 FPTRGSYLSLSLEFAGPYLGGDLEYYKLSADARYYFPlGKKLVLALRAEAGYLggYGKDLPFFERFYLGGFGSLRGYEEN 614
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2578669560 654 QLS----GQQVGIASLVYYRRILDARILPGYVGASIEFGNAWQNSSDVSFSSGLFNGSVFFGADTPIGPLYLGVGFA--- 726
Cdd:COG4775 615 SLGprlgGNAYLLGSAELRFPLPLPPSAGLRGALFVDAGNVWDSGDDFDLSDLRYSAGVGLRWDTPLGPLRLDYAYPldk 694
|
410
....*....|..
gi 2578669560 727 EGGTGTAFLHLG 738
Cdd:COG4775 695 EPGDSGQRFHFS 706
|
|
| PRK10279 |
PRK10279 |
patatin-like phospholipase RssA; |
40-327 |
1.35e-37 |
|
patatin-like phospholipase RssA;
Pssm-ID: 182352 [Multi-domain] Cd Length: 300 Bit Score: 142.54 E-value: 1.35e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2578669560 40 QRPRIGLVLGGGGARGSAHVGVLKVLEELHIPIDYIAGNSMGAIVGGLYAAgftpdeigHELKTID-WDDTF--IDQPPR 116
Cdd:PRK10279 2 RKIKIGLALGSGAARGWSHIGVINALKKVGIEIDIVAGCSIGSLVGAAYAC--------DRLSALEdWVTSFsyWDVLRL 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2578669560 117 TDRSFRRKlddnlymvkpklgfsddgevktplAYIHGQKFDLQLSRLtLRATDIHDFNklpIPFHAVATDLETGQAVVLQ 196
Cdd:PRK10279 74 MDLSWQRG------------------------GLLRGERVFNQYREI-MPETEIENCS---RRFGAVATNLSTGRELWFT 125
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2578669560 197 SGDLARAIRASMAVPGAFDPVEIDGRLLVDGLVANNVPVNVARDMGADILIVVDV-----------------------GS 253
Cdd:PRK10279 126 EGDLHLAIRASCSMPGLMAPVAHNGYWLVDGAVVNPVPVSLTRALGADIVIAVDLqhdahlmqqdllsfnvseensenGD 205
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2578669560 254 GLYKREDIK---------------GALDVVAQLTNILSERNVEQQLATlKPTDILIKPQLGDLGSGDFQRAGEGIVIGEA 318
Cdd:PRK10279 206 SLPWHARLKerlgsittrravtapTAMEIMTTSIQVLENRLKRNRMAG-DPPDILIQPVCPQISTLDFHRAHAAIAAGQL 284
|
....*....
gi 2578669560 319 AARGQLDAL 327
Cdd:PRK10279 285 AVEKKMDEL 293
|
|
| Pat_hypo_W_succinogenes_WS1459_like |
cd07210 |
Hypothetical patatin similar to WS1459 of Wolinella succinogenes; Patatin-like phospholipase. ... |
44-248 |
1.14e-34 |
|
Hypothetical patatin similar to WS1459 of Wolinella succinogenes; Patatin-like phospholipase. This family predominantly consists of bacterial patatin glycoproteins. The patatin protein accounts for up to 40% of the total soluble protein in potato tubers. Patatin is a storage protein, but it also has the enzymatic activity of a lipid acyl hydrolase, catalyzing the cleavage of fatty acids from membrane lipids. Members of this family have also been found in vertebrates.
Pssm-ID: 132849 [Multi-domain] Cd Length: 221 Bit Score: 131.70 E-value: 1.14e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2578669560 44 IGLVLGGGGARGSAHVGVLKVLEELHIPIDYIAGNSMGAIVGGLYAAGFTPDEIghelktidwddtfidqpprTDRSFRR 123
Cdd:cd07210 1 FALVLSSGFFGFYAHLGFLAALLEMGLEPSAISGTSAGALVGGLFASGISPDEM-------------------AELLLSL 61
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2578669560 124 KLDDNLYMVKPKlgfsddgevkTPLAYIHGQKFDLQLSRLTLratdIHDFNKLPIPFHAVATDLETGQAVVLQSGDLARA 203
Cdd:cd07210 62 ERKDFWMFWDPP----------LRGGLLSGDRFAALLREHLP----PDRFEELRIPLAVSVVDLTSRETLLLSEGDLAEA 127
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 2578669560 204 IRASMAVPGAFDPVEIDGRLLVDGLVANNVPVNVARDMGADILIV 248
Cdd:cd07210 128 VAASCAVPPLFQPVEIGGRPFVDGGVADRLPFDALRPEIERILYH 172
|
|
| Pat_PNPLA6_PNPLA7 |
cd07225 |
Patatin-like phospholipase domain containing protein 6 and protein 7; Patatin-like ... |
43-253 |
1.51e-33 |
|
Patatin-like phospholipase domain containing protein 6 and protein 7; Patatin-like phospholipase domain containing protein 6 (PNPLA6) and protein 7 (PNPLA7) are 60% identical to each other. PNPLA6 is commonly known as Neuropathy Target Esterase (NTE). NTE has at least two functional domains: the N-terminal domain putatively regulatory domain and the C-terminal catalytic domain which shows esterase activity. NTE shows phospholipase activity for lysophosphatidylcholine (LPC) and phosphatidylcholine (PC). Exposure of NTE to organophosphates leads to organophosphate-induced delayed neurotoxicity (OPIDN). OPIDN is a progressive neurological condition that is characterized by weakness, paralysis, pain, and paresthesia. PNPLA7 is an insulin-regulated phospholipase that is homologous to Neuropathy Target Esterase (NTE or PNPLA6) and is also known as NTE-related esterase (NRE). Human NRE is predominantly expressed in prostate, white adipose, and pancreatic tissue. NRE hydrolyzes sn-1 esters in lysophosphatidylcholine and lysophosphatidic acid, but shows no lipase activity with substrates like triacylglycerols (TG), cholesteryl esters, retinyl esters (RE), phosphatidylcholine (PC), or monoacylglycerol (MG). This family includes PNPLA6 and PNPLA7 from Homo sapiens, YMF9 from Yeast, and Swiss Cheese protein (sws) from Drosophila melanogaster.
Pssm-ID: 132864 [Multi-domain] Cd Length: 306 Bit Score: 130.98 E-value: 1.51e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2578669560 43 RIGLVLGGGGARGSAHVGVLKVLEELHIPIDYIAGNSMGAIVGGLYAAGFTPDEIGHELKTIDWDDTfidqpprtdrSFR 122
Cdd:cd07225 15 SIALVLGGGGARGCAHIGVIKALEEAGIPVDMVGGTSIGAFIGALYAEERNISRMKQRAREWAKDMT----------SIW 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2578669560 123 RKLDDNLYMVKPKlgFSDDGEVKTplayIHGQKFDLQlsrltlratdIHDfnkLPIPFHAVATDLETGQAVVLQSGDLAR 202
Cdd:cd07225 85 KKLLDLTYPITSM--FSGAAFNRS----IHSIFGDKQ----------IED---LWLPYFTITTDITASAMRVHTDGSLWR 145
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 2578669560 203 AIRASMAVPGAFDPV--EIDGRLLVDGLVANNVPVNVARDMGADILIVVDVGS 253
Cdd:cd07225 146 YVRASMSLSGYLPPLcdPKDGHLLMDGGYINNLPADVARSMGAKTVIAIDVGS 198
|
|
| Pat_hypo_Ecoli_Z1214_like |
cd07209 |
Hypothetical patatin similar to Z1214 protein of Escherichia coli; Patatin-like phospholipase ... |
46-331 |
1.90e-33 |
|
Hypothetical patatin similar to Z1214 protein of Escherichia coli; Patatin-like phospholipase similar to Z1214 protein of Escherichia coli. This family predominantly consists of bacterial patatin glycoproteins and some representatives from eukaryotes and archaea. The patatin protein accounts for up to 40% of the total soluble protein in potato tubers. Patatin is a storage protein, but it also has the enzymatic activity of a lipid acyl hydrolase, catalyzing the cleavage of fatty acids from membrane lipids. Members of this family have also been found in vertebrates.
Pssm-ID: 132848 [Multi-domain] Cd Length: 215 Bit Score: 127.79 E-value: 1.90e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2578669560 46 LVLGGGGARGSAHVGVLKVLEELHIPIDYIAGNSMGAIVGGLYAAGFTPD-EIGHEL-KTIDWDDTFidqpprtdrsfrr 123
Cdd:cd07209 1 LVLSGGGALGAYQAGVLKALAEAGIEPDIISGTSIGAINGALIAGGDPEAvERLEKLwRELSREDVF------------- 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2578669560 124 klddnlymvkpklgfsddgevktplayihgqkfdlqLSRLTLRATDIHDFNKLPIPF---HAVATDLETGQAVVLQSGDL 200
Cdd:cd07209 68 ------------------------------------LRGLLDRALDFDTLRLLAILFaglVIVAVNVLTGEPVYFDDIPD 111
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2578669560 201 AR---AIRASMAVPGAFDPVEIDGRLLVDGLVANNVPVNVARDMGADILIVVDVGSGlyKREDIKGALDVVAqltnilse 277
Cdd:cd07209 112 GIlpeHLLASAALPPFFPPVEIDGRYYWDGGVVDNTPLSPAIDLGADEIIVVSLSDK--GRDDRKGTPPTTL-------- 181
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....
gi 2578669560 278 rnveqqlatlkptdILIKPQLGDLGSGDFQRAGEGIvigeaaARGQLDALRRLS 331
Cdd:cd07209 182 --------------IEILPRLFLRSGLDSERIRHNL------ELGYLDTLRADS 215
|
|
| Pat_ExoU_VipD_like |
cd07207 |
ExoU and VipD-like proteins; homologus to patatin, cPLA2, and iPLA2; ExoU, a 74-kDa enzyme, is ... |
46-237 |
4.64e-31 |
|
ExoU and VipD-like proteins; homologus to patatin, cPLA2, and iPLA2; ExoU, a 74-kDa enzyme, is a potent virulence factor of Pseudomonas aeruginosa. One of the pathogenic mechanisms of P. aeruginosa is to induce cytotoxicity by the injection of effector proteins (e.g. ExoU) using the type III secretion (T3S) system. ExoU is homologus to patatin and also has the conserved catalytic residues of mammalian calcium-independent (iPLA2) and cytosolic (cPLA2) PLA2. In vitro, ExoU cytotoxity is blocked by the inhibitor of cytosolic and Ca2-independent phospholipase A2 (cPLA2 and iPLA2) enzymes, suggesting that phospholipase A2 inhibitors may represent a novel mode of treatment for acute P. aeruginosa infections. ExoU requires eukaryotic superoxide dismutase as a cofactor and cleaves phosphatidylcholine and phosphatidylethanolamine in vitro. VipD, a 69-kDa cytosolic protein, belongs to the members of Legionella pneumophila family and is homologus to ExoU from Pseudomonas. Even though VipD shows high sequence similarity with several functional regions of ExoU (e.g. oxyanion hole, active site serine, active site aspartate), it has been shown to have no phospholipase activity. This family includes ExoU from Pseudomonas aeruginosa and VipD of Legionella pneumophila.
Pssm-ID: 132846 Cd Length: 194 Bit Score: 120.46 E-value: 4.64e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2578669560 46 LVLGGGGARGSAHVGVLKVLEELHIPIDYIAGNSMGAIVGGLYAAGFTPDEIGHELKTIDWDDtFIDQPPRTDRSFRRKL 125
Cdd:cd07207 2 LVFEGGGAKGIAYIGALKALEEAGILKKRVAGTSAGAITAALLALGYSAADIKDILKETDFAK-LLDSPVGLLFLLPSLF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2578669560 126 DDN-LYMVKPKLGFSDDgevktplaYIHGQKFDLQLSRLTLRAtdihdFNKLPIPFHAVATDLETGQAVVLqSGD----- 199
Cdd:cd07207 81 KEGgLYKGDALEEWLRE--------LLKEKTGNSFATSLLRDL-----DDDLGKDLKVVATDLTTGALVVF-SAEttpdm 146
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 2578669560 200 -LARAIRASMAVPGAFDPVEID-GRLLVDGLVANNVPVNV 237
Cdd:cd07207 147 pVAKAVRASMSIPFVFKPVRLAkGDVYVDGGVLDNYPVWL 186
|
|
| Patatin |
pfam01734 |
Patatin-like phospholipase; This family consists of various patatin glycoproteins from plants. ... |
46-238 |
1.14e-30 |
|
Patatin-like phospholipase; This family consists of various patatin glycoproteins from plants. The patatin protein accounts for up to 40% of the total soluble protein in potato tubers. Patatin is a storage protein but it also has the enzymatic activity of lipid acyl hydrolase, catalysing the cleavage of fatty acids from membrane lipids. Members of this family have been found also in vertebrates.
Pssm-ID: 396341 Cd Length: 190 Bit Score: 119.25 E-value: 1.14e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2578669560 46 LVLGGGGARGSAHVGVLKVLEELHIPIDYIAGNSMGAIVGGLYAAGFTPDEIGHELKTIdWDDTFIDQPprtdRSFRRKL 125
Cdd:pfam01734 1 LVLSGGGARGAYHLGVLKALGEAGIRFDVISGTSAGAINAALLALGRDPEEIEDLLLEL-DLNLFLSLI----RKRALSL 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2578669560 126 DDNLYMVKPKLGFSDDGEVKTPLAYIHGqkfDLQLSRLT--LRATDIHDFNKLPIPFHAVATDLETGQAVVLQS--GDLA 201
Cdd:pfam01734 76 LALLRGLIGEGGLFDGDALRELLRKLLG---DLTLEELAarLSLLLVVALRALLTVISTALGTRARILLPDDLDddEDLA 152
|
170 180 190
....*....|....*....|....*....|....*..
gi 2578669560 202 RAIRASMAVPGAFDPVEIDGRLLVDGLVANNVPVNVA 238
Cdd:pfam01734 153 DAVLASSALPGVFPPVRLDGELYVDGGLVDNVPVEAA 189
|
|
| YjjU |
COG4667 |
Predicted phospholipase, patatin/cPLA2 family [Lipid transport and metabolism]; |
42-249 |
1.77e-30 |
|
Predicted phospholipase, patatin/cPLA2 family [Lipid transport and metabolism];
Pssm-ID: 443704 [Multi-domain] Cd Length: 281 Bit Score: 121.43 E-value: 1.77e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2578669560 42 PRIGLVLGGGGARGSAHVGVLKVLEELHIPIDYIAGNSMGAIVGGLYAAGftpdeighelktidwddtfidQPPRTDRSF 121
Cdd:COG4667 4 MKTALVLEGGGMRGIFTAGVLDALLEEGIPFDLVIGVSAGALNGASYLSR---------------------QPGRARRVI 62
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2578669560 122 RRKLDDNLYMVkpklgfsddgevktPLAYIHGQK-FDLQ-LSRLTLRATDIHDFNKL---PIPFHAVATDLETGQAVVLQ 196
Cdd:COG4667 63 TDYATDPRFFS--------------LRNFLRGGNlFDLDfLYDEIPNELLPFDFETFkasPREFYVVATNADTGEAEYFS 128
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 2578669560 197 ----SGDLARAIRASMAVPGAFDPVEIDGRLLVDGLVANNVPVNVARDMGADILIVV 249
Cdd:COG4667 129 kkddDYDLLDALRASSALPLLYPPVEIDGKRYLDGGVADSIPVREAIRDGADKIVVI 185
|
|
| Pat_Fungal_NTE1 |
cd07227 |
Fungal patatin-like phospholipase domain containing protein 6; These are fungal Neuropathy ... |
44-253 |
9.35e-30 |
|
Fungal patatin-like phospholipase domain containing protein 6; These are fungal Neuropathy Target Esterase (NTE), commonly referred to as NTE1. Patatin-like phospholipase. NTE has at least two functional domains: the N-terminal domain putatively regulatory domain and the C-terminal catalytic domain which shows esterase activity. NTE shows phospholipase activity for lysophosphatidylcholine (LPC) and phosphatidylcholine (PC). Exposure of NTE to organophosphates leads to organophosphate-induced delayed neurotoxicity (OPIDN). OPIDN is a progressive neurological condition that is characterized by weakness, paralysis, pain, and paresthesia. This family includes NTE1 from fungi.
Pssm-ID: 132865 [Multi-domain] Cd Length: 269 Bit Score: 119.14 E-value: 9.35e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2578669560 44 IGLVLGGGGARGSAHVGVLKVLEELHIPIDYIAGNSMGAIVGGLYAagftpdeighelktidWDDTFIDQPPRTDR---- 119
Cdd:cd07227 11 IGLVLGGGGARGISHIGILQALEEAGIPIDAIGGTSIGSFVGGLYA----------------READLVPIFGRAKKfagr 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2578669560 120 --SFRRKLDDNLYMVkpklgfsddgevktpLAYIHGQKFDLQLSRlTLRATDIHDFnklPIPFHAVATDLETGQAVVLQS 197
Cdd:cd07227 75 maSMWRFLSDVTYPF---------------ASYTTGHEFNRGIWK-TFGNTHIEDF---WIPFYANSTNITHSRMEIHSS 135
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 2578669560 198 GDLARAIRASMAVPGAFDPVEIDGRLLVDGLVANNVPVNVARDMGADILIVVDVGS 253
Cdd:cd07227 136 GYAWRYIRASMSLAGLLPPLSDNGSMLLDGGYMDNLPVSPMRSLGIRDIFAVDVGS 191
|
|
| TamA |
COG0729 |
Outer membrane translocation and assembly module TamA [Cell wall/membrane/envelope biogenesis]; ... |
186-741 |
5.75e-27 |
|
Outer membrane translocation and assembly module TamA [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440493 [Multi-domain] Cd Length: 574 Bit Score: 116.15 E-value: 5.75e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2578669560 186 DLETGQAVVLQSGDLARaIRASMAVPGAFDP-VEIDgrllVDGlvannvpvnvaRDMGADILIVVDVGSgLYKREDIkgA 264
Cdd:COG0729 47 DLDPAELRRLARADPER-IRAALRAEGYYSPtVTIR----LDG-----------RDGPWTVTITVDPGP-PVRIGKV--D 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2578669560 265 LDVVAQLTNILSERNVEQQLAtLKPTDILIkpqlgdlgSGDFQRAGEGIViGEAAARGQLDA---LRRLSASNAQYQQFE 341
Cdd:COG0729 108 IELLGEAAQDPARRKLLAAWP-LKPGDPLR--------HGAYEAAKSALL-DALRERGYPDArftQSRAEVDPATNTADV 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2578669560 342 AKKVpDKLPIIDF--VRLDNQSRIGDTVILSRISLKPGQALNSAQLDKEINEIYGLDVFESVRYEVVDEGGKTG---LVL 416
Cdd:COG0729 178 TLTV-DSGPRYRFgeITVEGLSRVPEDFLRRLAPFKPGEPYSPDKLLELQQRLQSTGYFSSVRVTPDEDPAPDGtvpVTV 256
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2578669560 417 HAKEKSwgPNYLQFGMELASDfnneSTYNLGVLYTRTAINALNGEIRLGLQIGQ-DPTVAAEWYQPLDPASRYfintrva 495
Cdd:COG0729 257 TLTERK--RRRIGFGLGYSTD----TGPRLSAGWEHRNLFGRGHRLRLELELSQpEQSLSADYRIPPLFPLGQ------- 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2578669560 496 laSNQFNVYAGNDAIAQYDVSRAVLDLGLGREFGTWGQARIGYLWSEGDVDmvIGPPSleGDFQIGQLYAQLAVDTLDSV 575
Cdd:COG0729 324 --YLSLGAGLEREDTDDYDSRSLTLGAGRTRRLSDGWTRSLGLRLLYERFT--DGDDD--RTYTLLSPGLSWTRDRRDDP 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2578669560 576 YFPGSGRKGGVSLIASQEALGADEDFNQVLLSYTEAFSSGRHH-LIGAFRFDTTLDDDA---PLESLFRAGGFLHLSGYR 651
Cdd:COG0729 398 LDPTRGYRLSLELGPGSKLLGSDTSFLRLYARGSWYRPLGERHrLAGRAELGAILGADFddvPPSLRFFAGGDGSVRGYG 477
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2578669560 652 PNQLS----------GQQVGIASLVYYRRILDarilPGYVGASIEFGNAWQNSSDVSFSSGlfngsVFFGA--DTPIGP- 718
Cdd:COG0729 478 YQSLGprdgdgdvigGRSLAVGSLEYRYRVTE----NWGLAVFVDAGNAFNDFPFSDLKVG-----AGLGLrwYSPVGPi 548
|
570 580
....*....|....*....|....*.
gi 2578669560 719 -LYLGVGFAEGGTGTAFLH--LGPVF 741
Cdd:COG0729 549 rLDLAYPLNDRDDSSFRLYisLGQAF 574
|
|
| Pat_hypo_Ecoli_yjju_like |
cd07208 |
Hypothetical patatin similar to yjju protein of Escherichia coli; Patatin-like phospholipase ... |
46-249 |
2.02e-24 |
|
Hypothetical patatin similar to yjju protein of Escherichia coli; Patatin-like phospholipase similar to yjju protein of Escherichia coli. This family predominantly consists of bacterial patatin glycoproteins, and some representatives from eukaryotes and archaea. The patatin protein accounts for up to 40% of the total soluble protein in potato tubers. Patatin is a storage protein, but it also has the enzymatic activity of a lipid acyl hydrolase, catalyzing the cleavage of fatty acids from membrane lipids. Members of this family have also been found in vertebrates.
Pssm-ID: 132847 [Multi-domain] Cd Length: 266 Bit Score: 103.46 E-value: 2.02e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2578669560 46 LVLGGGGARGSAHVGVLKVLEELHI-PIDYIAGNSMGAIVGGLYAAGftpdeighelktidwddtfidQPPRTDRSFRRK 124
Cdd:cd07208 1 LVLEGGGMRGAYTAGVLDAFLEAGIrPFDLVIGVSAGALNAASYLSG---------------------QRGRALRINTKY 59
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2578669560 125 LDDNLYMVKPKLgFSDDGEVKtpLAYIHGQKFDLQlsrltlratDIHDFNKL---PIPFHAVATDLETGQAVVLQSGD-- 199
Cdd:cd07208 60 ATDPRYLGLRSL-LRTGNLFD--LDFLYDELPDGL---------DPFDFEAFaasPARFYVVATDADTGEAVYFDKPDil 127
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 2578669560 200 --LARAIRASMAVPGAFDPVEIDGRLLVDGLVANNVPVNVARDMGADILIVV 249
Cdd:cd07208 128 ddLLDALRASSALPGLFPPVRIDGEPYVDGGLSDSIPVDKAIEDGADKIVVI 179
|
|
| Patatin |
cd07198 |
Patatin-like phospholipase; Patatin is a storage protein of the potato tuber that shows ... |
46-241 |
2.48e-23 |
|
Patatin-like phospholipase; Patatin is a storage protein of the potato tuber that shows Phospholipase A2 activity (PLA2; EC 3.1.1.4). Patatin catalyzes the nonspecific hydrolysis of phospholipids, glycolipids, sulfolipids, and mono- and diacylglycerols, thereby showing lipid acyl hydrolase activity. The active site includes an oxyanion hole with a conserved GGxR motif; it is found in almost all the members of this family. The catalytic dyad is formed by a serine and an aspartate. Patatin belongs to the alpha-beta hydrolase family which is identified by a characteristic nucleophile elbow with a consensus sequence of Sm-X-Nu-Sm (Sm = small residue, X = any residue and Nu = nucleophile). Members of this family have been found also in vertebrates. This family includes PNPLA (1-9), TGL (3-5), ExoU-like, and SDP1-like subfamilies. There are some additional hypothetical proteins included in this family.
Pssm-ID: 132837 [Multi-domain] Cd Length: 172 Bit Score: 97.41 E-value: 2.48e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2578669560 46 LVLGGGGARGSAHVGVLKVLEELHIPIDYIAGNSMGAIVGGLYAAGFTPDEIGhelktidwddtfidqpprtDRSFRRKL 125
Cdd:cd07198 1 LVLSGGGALGIYHVGVAKALRERGPLIDIIAGTSAGAIVAALLASGRDLEEAL-------------------LLLLRLSR 61
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2578669560 126 DDNLYmvkpklgfsdDGEVKTPLAYIHGqkfDLQLSRLTLRATDIHDFnkLPIPFHAVATDLETGQAVVLQ---SGDLAR 202
Cdd:cd07198 62 EVRLR----------FDGAFPPTGRLLG---ILRQPLLSALPDDAHED--ASGKLFISLTRLTDGENVLVSdtsKGELWS 126
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 2578669560 203 AIRASMAVPGAFDPVE--IDGRLLVDGLVANNVPVNVARDM 241
Cdd:cd07198 127 AVRASSSIPGYFGPVPlsFRGRRYGDGGLSNNLPVAELGNT 167
|
|
| PATA |
COG3621 |
Patatin-like phospholipase/acyl hydrolase, includes sporulation protein CotR [General function ... |
43-287 |
8.13e-14 |
|
Patatin-like phospholipase/acyl hydrolase, includes sporulation protein CotR [General function prediction only];
Pssm-ID: 442839 [Multi-domain] Cd Length: 296 Bit Score: 72.63 E-value: 8.13e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2578669560 43 RIgLVLGGGGARGSAHVGVLKVLEE-LHIPI----DYIAGNSMGAIVGGLYAAGFTPDEIGhelktidwdDTFIDQPPRT 117
Cdd:COG3621 8 RI-LSLDGGGIRGLIPARILAELEErLGKPLaeyfDLIAGTSTGGIIALGLAAGYSAEEIL---------DLYEEEGKEI 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2578669560 118 -DRSFRRKLDDNLYMVKPKlgFSDDGEVKTpLAYIHGqkfDLQLSRLTLRatdihdfnkLPIPfhavATDLETGQAVVLQ 196
Cdd:COG3621 78 fPKSRWRKLLSLRGLFGPK--YDSEGLEKV-LKEYFG---DTTLGDLKTP---------VLIP----SYDLDNGKPVFFK 138
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2578669560 197 SGD----------LARAIRASMAVPGAFDPVEID-----GRLLVDG-LVANNvPVNVA-----RDMGADI--LIVVDVGS 253
Cdd:COG3621 139 SPHakfdrdrdflLVDVARATSAAPTYFPPAQIKnltgeGYALIDGgVFANN-PALCAlaealKLLGPDLddILVLSLGT 217
|
250 260 270 280
....*....|....*....|....*....|....*....|...
gi 2578669560 254 GLYKR----EDIK--GALDVVAQLTNIL---SERNVEQQLATL 287
Cdd:COG3621 218 GTAPRsipyKKVKnwGALGWLLPLIDILmdaQSDAVDYQLRQL 260
|
|
| OM_YaeT |
TIGR03303 |
outer membrane protein assembly complex, YaeT protein; Members of this protein family are the ... |
361-726 |
1.31e-09 |
|
outer membrane protein assembly complex, YaeT protein; Members of this protein family are the YaeT protein of the YaeT/YfiO complex for assembling proteins into the outer membrane of Gram-negative bacteria. This protein is similar in sequence and function to a non-essential paralog, YtfM, that is also in the Omp85 family. Members of this family typically have five tandem copies of the surface antigen variable number repeat (pfam07244), followed by an outer membrane beta-barrel domain (pfam01103), while the YtfM family typically has a single pfam07244 repeat. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 274514 [Multi-domain] Cd Length: 741 Bit Score: 61.44 E-value: 1.31e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2578669560 361 SRIGDTVILSRISLKPGQALNSAQLDKEINEIYGLDVFESVRYEV--VDEGGKTGLVLHAKEKSWGPnyLQFGMelasDF 438
Cdd:TIGR03303 333 TRTRDEVIRRELRQLEGDWYSLSKIKRSKRRLERLGYFETVNIETvpVGSPDQVDLNVKVKEQPTGS--ISFGV----GY 406
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2578669560 439 NNESTYNLGVlytrtAINALN--G---EIRLGLQIGQDPTVAAEWYQplDPasrYFINTRVALASNQF-NVYAGNDA-IA 511
Cdd:TIGR03303 407 GSSSGLSFNA-----SISERNflGtgnRLSLSANKSSLSTSYSLSFT--DP---YFTDDGVSLGFSIFySETDRNYKnFS 476
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2578669560 512 QYDVSRAVLDLGLGREFGTWGQARIGYLWSEGDVDMVIGPPS--------LEGDFQIGQLYAQLAVDTLDSVYFPgsgrK 583
Cdd:TIGR03303 477 DYKTKTYGGSINLGYPITEYLRVSLGYGYEQNKIKDDSDSDSsasyfikeQGGKFIDSSLSYGWSYDTLDSGYFP----T 552
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2578669560 584 GGVSLIASQEA--LGADEDFNQVLLSYTEAFS-SGRHHLIGAFRFDTTL-----DDDAPLESLFRAGGFLHLSGYRPNQL 655
Cdd:TIGR03303 553 KGSIQRLSQEFagPGGDLKYYKLTYDSEYYIPlSKEDDWVLSLRGRLGYgngygGKDLPFYERFYAGGIGSVRGFESNGI 632
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2578669560 656 SGQQVGiaslvyyrriLDARILPG--YVGASIE---------------------FGNAWQNSSDVSFSSGLFNG---SVF 709
Cdd:TIGR03303 633 GPRDIN----------DSGDSIGGnaMATANVElifplpflpednglrgsvffdAGNVWGTDQKKEGDYSDDSSlraSVG 702
|
410
....*....|....*....
gi 2578669560 710 FGAD--TPIGPLYLGVGFA 726
Cdd:TIGR03303 703 VGLRwiSPMGPLRFSYAKP 721
|
|
| Omp85 |
pfam01103 |
Omp85 superfamily domain; The Omp85 protein superfamily contains bacterial outer membrane ... |
462-725 |
1.80e-08 |
|
Omp85 superfamily domain; The Omp85 protein superfamily contains bacterial outer membrane proteins, which can function as protein translocases or as membrane protein assembly factors. The family includes the membrane bound beta barrel of proteins such as BamA and TamA from E. coli.
Pssm-ID: 460065 [Multi-domain] Cd Length: 319 Bit Score: 56.60 E-value: 1.80e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2578669560 462 IRLGLQIGQDPT-VAAEWYQPldpasrYFINTRVALAsnqFNVYAGN-----DAIAQYDVSRAVLDLGLGREFGTWGQAR 535
Cdd:pfam01103 9 LSVNASRGSYETsFSLSFTDP------YFLGDGVSLG---GSLFYNSydsdrDSSDSYRITTYGFSVSLGRPITENWSLS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2578669560 536 IGYLWSEGDVD--------MVIGPPSLE-GDFQIGQLYAQLAVDTLDSVYFPGSGRKGGVSLIASQEALGADEDFNQVLL 606
Cdd:pfam01103 80 LGLGYQHNKILdesgspniRNYYPSASGtGKSLTFSLSYGWTYDTRDDGLFPTRGSYLKFNLEFTGPFLGGDVSYYKLTA 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2578669560 607 SYTEAFS-SGRHHLIGAFRF-----DTTLDDDAPLESLFRAGGFLHLSGYR-----PNQLSGQQVG-----IASLVYYRR 670
Cdd:pfam01103 160 DGSYYYPlGKDDSFVLSARValgylDGYGTKDLPFYERFYAGGSNSVRGFEyggigPRDEDGDALGgnsyvVASLELRFP 239
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2578669560 671 ILDARILPGYVGASIEFGNAWQNSSDVSFSSGLFNGSVFFGA--------DTPIGPLYLGVGF 725
Cdd:pfam01103 240 LPFVPKQSVRGVLFFDAGNVWNTGSTDPGSSRGARSKAGIRAsvgvglrwLSPLGPLRFDYAF 302
|
|
| Pat_PNPLA8 |
cd07211 |
Patatin-like phospholipase domain containing protein 8; PNPLA8 is a Ca-independent myocardial ... |
43-256 |
1.44e-07 |
|
Patatin-like phospholipase domain containing protein 8; PNPLA8 is a Ca-independent myocardial phospholipase which maintains mitochondrial integrity. PNPLA8 is also known as iPLA2-gamma. In humans, it is predominantly expressed in heart tissue. iPLA2-gamma can catalyze both phospholipase A1 and A2 reactions (PLA1 and PLA2 respectively). This family includes PNPLA8 (iPLA2-gamma) from Homo sapiens and iPLA2-2 from Mus musculus.
Pssm-ID: 132850 [Multi-domain] Cd Length: 308 Bit Score: 53.80 E-value: 1.44e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2578669560 43 RIgLVLGGGGARGSAHVGVLKVLEELHI-PI----DYIAGNSMGAIVG-GLYAAGFTPDEIGhelktidwddtfidqppR 116
Cdd:cd07211 9 RI-LSIDGGGTRGVVALEILRKIEKLTGkPIhelfDYICGVSTGAILAfLLGLKKMSLDECE-----------------E 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2578669560 117 TDRSFRRKL-DDNLYMVKP-KLGFSddgevktpLAYIHGQKFDLQLSRLTLRATDIHDFNKLPIP-FHAVAT--DLETGQ 191
Cdd:cd07211 71 LYRKLGKDVfSQNTYISGTsRLVLS--------HAYYDTETWEKILKEMMGSDELIDTSADPNCPkVACVSTqvNRTPLK 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2578669560 192 AVVLQS----------------GDLARAIRASMAVPGAFDPVEIDGRLLVDG-LVANN---VPVNVARDMGADILI--VV 249
Cdd:cd07211 143 PYVFRNynhppgtrshylgsckHKLWEAIRASSAAPGYFEEFKLGNNLHQDGgLLANNptaLALHEAKLLWPDTPIqcLV 222
|
....*..
gi 2578669560 250 DVGSGLY 256
Cdd:cd07211 223 SVGTGRY 229
|
|
| Patatin_and_cPLA2 |
cd01819 |
Patatins and Phospholipases; Patatin-like phospholipase. This family consists of various ... |
46-247 |
5.11e-07 |
|
Patatins and Phospholipases; Patatin-like phospholipase. This family consists of various patatin glycoproteins from plants. The patatin protein accounts for up to 40% of the total soluble protein in potato tubers. Patatin is a storage protein, but it also has the enzymatic activity of a lipid acyl hydrolase, catalyzing the cleavage of fatty acids from membrane lipids. Members of this family have also been found in vertebrates. This family also includes the catalytic domain of cytosolic phospholipase A2 (PLA2; EC 3.1.1.4) hydrolyzes the sn-2-acyl ester bond of phospholipids to release arachidonic acid. At the active site, cPLA2 contains a serine nucleophile through which the catalytic mechanism is initiated. The active site is partially covered by a solvent-accessible flexible lid. cPLA2 displays interfacial activation as it exists in both "closed lid" and "open lid" forms.
Pssm-ID: 132836 [Multi-domain] Cd Length: 155 Bit Score: 50.11 E-value: 5.11e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2578669560 46 LVLGGGGARGSAHVGVLKVLEE--LHIPIDYIAGNSMGAIVgglyAAGFTPdeighelktidwddtfidqpprtdrsfrr 123
Cdd:cd01819 1 LSFSGGGFRGMYHAGVLSALAErgLLDCVTYLAGTSGGAWV----AATLYP----------------------------- 47
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2578669560 124 klddnlymvkpkLGFSDDGEVKTPLayihgqkfdlqlsrltlratDIHDFNKLPIPFhavaTDLETGQAVVLQSG----D 199
Cdd:cd01819 48 ------------PSSSLDNKPRQSL--------------------EEALSGKLWVSF----TPVTAGENVLVSRFvskeE 91
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2578669560 200 LARAIRASMAVPGAF------------DPVEIDGRLLVDGLVANNVP--VNVARDMGADILI 247
Cdd:cd01819 92 LIRALFASGSWPSYFglippaelytskSNLKEKGVRLVDGGVSNNLPapVLLRPGRGVTLTI 153
|
|
| Pat17_PNPLA8_PNPLA9_like |
cd07199 |
Patatin-like phospholipase; includes PNPLA8, PNPLA9, and Pat17; Patatin is a storage protein ... |
46-254 |
8.06e-06 |
|
Patatin-like phospholipase; includes PNPLA8, PNPLA9, and Pat17; Patatin is a storage protein of the potato tuber that shows Phospholipase A2 activity (PLA2; EC 3.1.1.4). Patatin catalyzes the nonspecific hydrolysis of phospholipids, glycolipids, sulfolipids, and mono- and diacylglycerols, thereby showing lipid acyl hydrolase activity. The active site includes an oxyanion hole with a conserved GGxR motif; it is found in almost all the members of this family. The catalytic dyad is formed by a serine and an aspartate. Patatin belongs to the alpha-beta hydrolase family which is identified by a characteristic nucleophile elbow with a consensus sequence of Sm-X-Nu-Sm (Sm = small residue, X = any residue and Nu = nucleophile). Members of this family have been found also in vertebrates. This family includes subfamily of PNPLA8 (iPLA2-gamma) and PNPLA9 (iPLA2-beta) like phospholipases from human as well as the Pat17 isozyme from Solanum cardiophyllum.
Pssm-ID: 132838 [Multi-domain] Cd Length: 258 Bit Score: 48.10 E-value: 8.06e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2578669560 46 LVLGGGGARGSAHVGVLKVLEEL---HIPI----DYIAGNSMGAIVGGLYAAG-FTPDEIGhelktidwddtfidqpprt 117
Cdd:cd07199 2 LSLDGGGIRGIIPAEILAELEKRlgkPSRIadlfDLIAGTSTGGIIALGLALGrYSAEELV------------------- 62
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2578669560 118 drsfrrklddNLYMVkpklgfsddgevktplayiHGQKFdlqlsrltlratdihdFNKLPIPfhavATDLETGQAVVLQS 197
Cdd:cd07199 63 ----------ELYEE-------------------LGRKI----------------FPRVLVT----AYDLSTGKPVVFSN 93
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2578669560 198 GD-----------LARAIRASMAVPGAFDPVEI----DGRLLVDG-LVANNvPVNVA-------RDMGADILIVVDVGSG 254
Cdd:cd07199 94 YDaeepdddddfkLWDVARATSAAPTYFPPAVIesggDEGAFVDGgVAANN-PALLAlaealrlLAPDKDDILVLSLGTG 172
|
|
| Pat_SDP1-like |
cd07231 |
Sugar-Dependent 1 like lipase; Sugar-Dependent 1 (SDP1) lipase has a patatin-like ... |
43-119 |
8.45e-06 |
|
Sugar-Dependent 1 like lipase; Sugar-Dependent 1 (SDP1) lipase has a patatin-like acyl-hydrolase domain that initiates the breakdown of storage oil in germinating Arabidopsis seeds. This acyl-hydrolase domain is homologus to yeast triacylglycerol lipase 3 and human adipose triglyceride lipase. This family includes SDP1 from Arabidopsis thaliana.
Pssm-ID: 132869 Cd Length: 323 Bit Score: 48.60 E-value: 8.45e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2578669560 43 RIGLVLGGGGARGSAHVGVLKVLEELHIPIDYIAGNSMGAIVGGLyAAGFTPDEIGHELKTIDWDDTFIDQPPRTDR 119
Cdd:cd07231 68 RTALLLSGGAALGTFHVGVVRTLVEHQLLPRVIAGSSVGSIVCAI-IATRTDEELQSFFRALLGDLTFQEAYDRTGR 143
|
|
| OM_YaeT |
TIGR03303 |
outer membrane protein assembly complex, YaeT protein; Members of this protein family are the ... |
351-421 |
8.13e-05 |
|
outer membrane protein assembly complex, YaeT protein; Members of this protein family are the YaeT protein of the YaeT/YfiO complex for assembling proteins into the outer membrane of Gram-negative bacteria. This protein is similar in sequence and function to a non-essential paralog, YtfM, that is also in the Omp85 family. Members of this family typically have five tandem copies of the surface antigen variable number repeat (pfam07244), followed by an outer membrane beta-barrel domain (pfam01103), while the YtfM family typically has a single pfam07244 repeat. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 274514 [Multi-domain] Cd Length: 741 Bit Score: 46.04 E-value: 8.13e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2578669560 351 IIDFVRLDNQSRIGDTVILSRISLKPGQALNSAQLDKEINEIYGLDVFESVRyeVVDEGGKtgLVLHAKEK 421
Cdd:TIGR03303 2 VVKDIRVEGLQRVSEGTVLNYLPVKVGDTISDEKIDEAIKALYATGYFEDVK--IEREGGV--LVIKVKER 68
|
|
| Pat_TGL3-4-5_SDP1 |
cd07206 |
Triacylglycerol lipase 3, 4, and 5 and Sugar-Dependent 1 lipase; Triacylglycerol lipases are ... |
43-87 |
1.62e-04 |
|
Triacylglycerol lipase 3, 4, and 5 and Sugar-Dependent 1 lipase; Triacylglycerol lipases are involved in triacylglycerol mobilization and degradation; they are found in lipid particles. TGL4 is 30% homologus to TGL3, whereas TGL5 is 26% homologus to TGL3. Sugar-Dependent 1 (SDP1) lipase has a patatin-like acyl-hydrolase domain that initiates the breakdown of storage oil in germinating Arabidopsis seeds. This family includes subfamilies of proteins: TGL3, TGL4, TGL5, and SDP1.
Pssm-ID: 132845 Cd Length: 298 Bit Score: 44.12 E-value: 1.62e-04
10 20 30 40
....*....|....*....|....*....|....*....|....*
gi 2578669560 43 RIGLVLGGGGARGSAHVGVLKVLEELHIPIDYIAGNSMGAIVGGL 87
Cdd:cd07206 69 RTALMLSGGASLGLFHLGVVKALWEQDLLPRVISGSSAGAIVAAL 113
|
|
| Pat_PLPL |
cd07232 |
Patain-like phospholipase; Patatin-like phospholipase. This family consists of various patatin ... |
43-116 |
3.93e-04 |
|
Patain-like phospholipase; Patatin-like phospholipase. This family consists of various patatin glycoproteins from plants and fungi. The patatin protein accounts for up to 40% of the total soluble protein in potato tubers. Patatin is a storage protein, but it also has the enzymatic activity of a lipid acyl hydrolase, catalyzing the cleavage of fatty acids from membrane lipids. Members of this family have been found also in vertebrates.
Pssm-ID: 132870 Cd Length: 407 Bit Score: 43.41 E-value: 3.93e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2578669560 43 RIGLVLGGGGARGSAHVGVLKVLEELHIPIDYIAGNSMGAIVGGLyAAGFTPDEIGHEL------KTIDWDDTFIDQPPR 116
Cdd:cd07232 67 RTALCLSGGAAFAYYHFGVVKALLDADLLPNVISGTSGGSLVAAL-LCTRTDEELKQLLvpelarKITACEPPWLVWIPR 145
|
|
| Pat_TGL4-5_like |
cd07230 |
Triacylglycerol lipase 4 and 5; TGL4 and TGL5 are triacylglycerol lipases that are involved in ... |
43-97 |
1.97e-03 |
|
Triacylglycerol lipase 4 and 5; TGL4 and TGL5 are triacylglycerol lipases that are involved in triacylglycerol mobilization and degradation; they are found in lipid particles. Tgl4 is a functional ortholog of mammalian adipose TG lipase (ATGL) and is phosphorylated and activated by cyclin-dependent kinase 1 (Cdk1/Cdc28). TGL4 is 30% homologus to TGL3, whereas TGL5 is 26% homologus to TGL3. This family includes TGL4 (STC1) and TGL5 (STC2) from Saccharomyces cerevisiae.
Pssm-ID: 132868 Cd Length: 421 Bit Score: 41.44 E-value: 1.97e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 2578669560 43 RIGLVLGGGGARGSAHVGVLKVLEELHIPIDYIAGNSMGAIVgglyAAGF---TPDEI 97
Cdd:cd07230 73 RTALLLSGGGTFGMFHIGVLKALFEANLLPRIISGSSAGSIV----AAILcthTDEEI 126
|
|
| BamA |
COG4775 |
Outer membrane protein assembly factor BamA [Cell wall/membrane/envelope biogenesis]; |
362-421 |
2.95e-03 |
|
Outer membrane protein assembly factor BamA [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 443807 [Multi-domain] Cd Length: 711 Bit Score: 40.85 E-value: 2.95e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2578669560 362 RIGDTVILSRISLKPGQALNSAQLDKEINEIYGLDVFESVRYEVvdEGGKtgLVLHAKEK 421
Cdd:COG4775 11 RVEAGTVLSYLPLRVGDTFDDEKLDEAIKALYATGLFSDVRIER--EGVV--LVVKVKER 66
|
|
| |
