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Conserved domains on  [gi|2620665810|ref|WP_318764254|]
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monovalent cation/H(+) antiporter subunit G [Aminobacter niigataensis]

Protein Classification

cation:proton antiporter( domain architecture ID 10003540)

cation:proton antiporter functions in maintaining cation homeostasis and the pH of actively metabolizing cells; it may also be involved in regulating cell volume; similar to Alkalihalophilus pseudofirmus Na(+)/H(+) antiporter subunit G

Gene Ontology:  GO:0015297|GO:0098662|GO:1902600
PubMed:  12027219|16734752|12502567|17218973|9537504
TCDB:  2.A.63

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
MnhG COG1320
Multisubunit Na+/H+ antiporter, MnhG subunit [Inorganic ion transport and metabolism];
11-94 3.91e-14

Multisubunit Na+/H+ antiporter, MnhG subunit [Inorganic ion transport and metabolism];


:

Pssm-ID: 440931  Cd Length: 110  Bit Score: 62.58  E-value: 3.91e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2620665810  11 GLLRLPDF----HTVSKAGTVGSCPELLRRAVHIGELSTALPARAGVVFFMLMAPISADLLAKAAYSAGYRLWQGSLSDD 86
Cdd:COG1320    23 GLLRLPDFytrlHAATKATTLGLGLILLGVALYFGSGAVSLKLLLIILFLLLTAPVAAHLLARAAYRSGVPPWEKTVVDE 102


                  ....*...
gi 2620665810  87 LAETVARD 94
Cdd:COG1320   103 LAEDLDRE 110
 
Name Accession Description Interval E-value
MnhG COG1320
Multisubunit Na+/H+ antiporter, MnhG subunit [Inorganic ion transport and metabolism];
11-94 3.91e-14

Multisubunit Na+/H+ antiporter, MnhG subunit [Inorganic ion transport and metabolism];


Pssm-ID: 440931  Cd Length: 110  Bit Score: 62.58  E-value: 3.91e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2620665810  11 GLLRLPDF----HTVSKAGTVGSCPELLRRAVHIGELSTALPARAGVVFFMLMAPISADLLAKAAYSAGYRLWQGSLSDD 86
Cdd:COG1320    23 GLLRLPDFytrlHAATKATTLGLGLILLGVALYFGSGAVSLKLLLIILFLLLTAPVAAHLLARAAYRSGVPPWEKTVVDE 102


                  ....*...
gi 2620665810  87 LAETVARD 94
Cdd:COG1320   103 LAEDLDRE 110
PRK12674 PRK12674
putative monovalent cation/H+ antiporter subunit G; Reviewed
 11-82 5.76e-12

putative monovalent cation/H+ antiporter subunit G; Reviewed


Pssm-ID: 237169  Cd Length: 99  Bit Score: 56.76  E-value: 5.76e-12
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2620665810  11 GLLRLPDF----HTVSKAGTVGSCPELLRRAVHIGELSTALPARAGVVFFMLMAPISADLLAKAAYSAGYRLWQGS 82
Cdd:PRK12674   24 GLVRLPDVytrlHAATKATTLGLGLVLLASALYFAGGGNSLKALLIILFLFLTAPVAAHLLARAAYRTGVPLWDRS 99
CPA3_mnhG_phaG TIGR01300
monovalent cation/proton antiporter, MnhG/PhaG subunit; This model represents a subfamily of ...
 11-81 1.55e-07

monovalent cation/proton antiporter, MnhG/PhaG subunit; This model represents a subfamily of small, transmembrane proteins believed to be components of Na+/H+ and K+/H+ antiporters. Members, including proteins designated MnhG from Staphylococcus aureus and PhaG from Rhizobium meliloti, show some similarity to chain L of the NADH dehydrogenase I, which also translocates protons. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 130367  Cd Length: 97  Bit Score: 45.39  E-value: 1.55e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2620665810  11 GLLRLPDF----HTVSKAGTVGSCPELLRRAVHIGELSTALPARA--GVVFFMLMAPISADLLAKAAYSAGYRLWQG 81
Cdd:TIGR01300  16 GLVRFPDVytrlHAATKGTTLGTILILLGVALIALVLDLAVSIKLllIALFILLTNPVGAHLLARAAYLSGVKPSRS 92
PhaG_MnhG_YufB pfam03334
Na+/H+ antiporter subunit; This family includes PhaG from Rhizobium meliloti, MnhG from ...
 11-72 2.73e-07

Na+/H+ antiporter subunit; This family includes PhaG from Rhizobium meliloti, MnhG from Staphylococcus aureus, YufB from Bacillus subtilis.


Pssm-ID: 460887  Cd Length: 82  Bit Score: 44.36  E-value: 2.73e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2620665810  11 GLLRLPDF----HTVSKAGTVGSCPELLRRAVHIGELSTALPARA--GVVFFMLMAPISADLLAKAAY 72
Cdd:pfam03334  15 GLLRLPDVytrlHAATKADTLGLGLILLGLALYFGLGGGGVALKLllIILFLLLTAPVAAHLIARAAY 82
 
Name Accession Description Interval E-value
MnhG COG1320
Multisubunit Na+/H+ antiporter, MnhG subunit [Inorganic ion transport and metabolism];
11-94 3.91e-14

Multisubunit Na+/H+ antiporter, MnhG subunit [Inorganic ion transport and metabolism];


Pssm-ID: 440931  Cd Length: 110  Bit Score: 62.58  E-value: 3.91e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2620665810  11 GLLRLPDF----HTVSKAGTVGSCPELLRRAVHIGELSTALPARAGVVFFMLMAPISADLLAKAAYSAGYRLWQGSLSDD 86
Cdd:COG1320    23 GLLRLPDFytrlHAATKATTLGLGLILLGVALYFGSGAVSLKLLLIILFLLLTAPVAAHLLARAAYRSGVPPWEKTVVDE 102


                  ....*...
gi 2620665810  87 LAETVARD 94
Cdd:COG1320   103 LAEDLDRE 110
PRK12674 PRK12674
putative monovalent cation/H+ antiporter subunit G; Reviewed
 11-82 5.76e-12

putative monovalent cation/H+ antiporter subunit G; Reviewed


Pssm-ID: 237169  Cd Length: 99  Bit Score: 56.76  E-value: 5.76e-12
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2620665810  11 GLLRLPDF----HTVSKAGTVGSCPELLRRAVHIGELSTALPARAGVVFFMLMAPISADLLAKAAYSAGYRLWQGS 82
Cdd:PRK12674   24 GLVRLPDVytrlHAATKATTLGLGLVLLASALYFAGGGNSLKALLIILFLFLTAPVAAHLLARAAYRTGVPLWDRS 99
CPA3_mnhG_phaG TIGR01300
monovalent cation/proton antiporter, MnhG/PhaG subunit; This model represents a subfamily of ...
 11-81 1.55e-07

monovalent cation/proton antiporter, MnhG/PhaG subunit; This model represents a subfamily of small, transmembrane proteins believed to be components of Na+/H+ and K+/H+ antiporters. Members, including proteins designated MnhG from Staphylococcus aureus and PhaG from Rhizobium meliloti, show some similarity to chain L of the NADH dehydrogenase I, which also translocates protons. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 130367  Cd Length: 97  Bit Score: 45.39  E-value: 1.55e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2620665810  11 GLLRLPDF----HTVSKAGTVGSCPELLRRAVHIGELSTALPARA--GVVFFMLMAPISADLLAKAAYSAGYRLWQG 81
Cdd:TIGR01300  16 GLVRFPDVytrlHAATKGTTLGTILILLGVALIALVLDLAVSIKLllIALFILLTNPVGAHLLARAAYLSGVKPSRS 92
PhaG_MnhG_YufB pfam03334
Na+/H+ antiporter subunit; This family includes PhaG from Rhizobium meliloti, MnhG from ...
 11-72 2.73e-07

Na+/H+ antiporter subunit; This family includes PhaG from Rhizobium meliloti, MnhG from Staphylococcus aureus, YufB from Bacillus subtilis.


Pssm-ID: 460887  Cd Length: 82  Bit Score: 44.36  E-value: 2.73e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2620665810  11 GLLRLPDF----HTVSKAGTVGSCPELLRRAVHIGELSTALPARA--GVVFFMLMAPISADLLAKAAY 72
Cdd:pfam03334  15 GLLRLPDVytrlHAATKADTLGLGLILLGLALYFGLGGGGVALKLllIILFLLLTAPVAAHLIARAAY 82
PRK12586 PRK12586
Na+/H+ antiporter subunit G;
11-97 9.30e-06

Na+/H+ antiporter subunit G;


Pssm-ID: 237147  Cd Length: 145  Bit Score: 41.68  E-value: 9.30e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2620665810  11 GLLRLPDFHTVSKAGTVGSCPELLRR--------AVHIGELSTALpaRAGVVFFMLMAPISADLLAKAAYSAGYRLWQGS 82
Cdd:PRK12586   29 GIVKFQDVFLRSHAATKSSTLSVLLTligvliyfIVNTGFFSVRL--LLSLVFINLTSPVGMHLIARAAYRNGAYMYRKN 106

                          90
                  ....*....|....*
gi 2620665810  83 LSDDLAETVARDKKN 97
Cdd:PRK12586  107 DAHTHASILLSSNEQ 121
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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