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Conserved domains on  [gi|2623587679|ref|WP_319641024|]
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polymorphic toxin type 15 domain-containing protein [Pseudoalteromonas sp. A3]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Ntox15 super family cl21405
Novel toxin 15; A predicted RNase toxin found in bacterial polymorphic toxin systems. The ...
 136-293 5.98e-28

Novel toxin 15; A predicted RNase toxin found in bacterial polymorphic toxin systems. The toxin possesses a most all-alpha helical fold and a conserved HxxD motif. In bacterial polymorphic toxin systems, the toxin is usually exported by the type 2, type 6, type 7 or Photorhabdus virulence cassette (PVC)-type secretion systems. This is shown to be a type IV secretion system protein that behaves as DNase.


The actual alignment was detected with superfamily member pfam15604:

Pssm-ID: 406122 [Multi-domain]  Cd Length: 154  Bit Score: 105.36  E-value: 5.98e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2623587679 136 KEFYKQLKAQQEGINKMSVGDYLKNRetltDLVKEHGHAkarkilTNNGAAQQKARDELFDEIKESAAESFMKQGNISFK 215
Cdd:pfam15604   5 EEFARQLKRQQDALNNMTVDEYLKNR----DKYKTQGRA------PRALAEQRQARARQEYRNRERLEKKIVDKGVNDYR 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2623587679 216 KADELAIQKASSTLEELAALHDPDMIAGGH--DKISRLGNSNVNSSLGSQWAKadRVAGMDKAAKEAMDLHGPDAKMNVE 293
Cdd:pfam15604  75 EDPIQAEKKAAEALKSLAALHEPDQVAGGQlsVDIIGMGDKSVNSSIGSQWKT--RLSRLDEKAKSAAADGKGSVYLNVR 152
 
Name Accession Description Interval E-value
Ntox15 pfam15604
Novel toxin 15; A predicted RNase toxin found in bacterial polymorphic toxin systems. The ...
 136-293 5.98e-28

Novel toxin 15; A predicted RNase toxin found in bacterial polymorphic toxin systems. The toxin possesses a most all-alpha helical fold and a conserved HxxD motif. In bacterial polymorphic toxin systems, the toxin is usually exported by the type 2, type 6, type 7 or Photorhabdus virulence cassette (PVC)-type secretion systems. This is shown to be a type IV secretion system protein that behaves as DNase.


Pssm-ID: 406122 [Multi-domain]  Cd Length: 154  Bit Score: 105.36  E-value: 5.98e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2623587679 136 KEFYKQLKAQQEGINKMSVGDYLKNRetltDLVKEHGHAkarkilTNNGAAQQKARDELFDEIKESAAESFMKQGNISFK 215
Cdd:pfam15604   5 EEFARQLKRQQDALNNMTVDEYLKNR----DKYKTQGRA------PRALAEQRQARARQEYRNRERLEKKIVDKGVNDYR 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2623587679 216 KADELAIQKASSTLEELAALHDPDMIAGGH--DKISRLGNSNVNSSLGSQWAKadRVAGMDKAAKEAMDLHGPDAKMNVE 293
Cdd:pfam15604  75 EDPIQAEKKAAEALKSLAALHEPDQVAGGQlsVDIIGMGDKSVNSSIGSQWKT--RLSRLDEKAKSAAADGKGSVYLNVR 152
 
Name Accession Description Interval E-value
Ntox15 pfam15604
Novel toxin 15; A predicted RNase toxin found in bacterial polymorphic toxin systems. The ...
 136-293 5.98e-28

Novel toxin 15; A predicted RNase toxin found in bacterial polymorphic toxin systems. The toxin possesses a most all-alpha helical fold and a conserved HxxD motif. In bacterial polymorphic toxin systems, the toxin is usually exported by the type 2, type 6, type 7 or Photorhabdus virulence cassette (PVC)-type secretion systems. This is shown to be a type IV secretion system protein that behaves as DNase.


Pssm-ID: 406122 [Multi-domain]  Cd Length: 154  Bit Score: 105.36  E-value: 5.98e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2623587679 136 KEFYKQLKAQQEGINKMSVGDYLKNRetltDLVKEHGHAkarkilTNNGAAQQKARDELFDEIKESAAESFMKQGNISFK 215
Cdd:pfam15604   5 EEFARQLKRQQDALNNMTVDEYLKNR----DKYKTQGRA------PRALAEQRQARARQEYRNRERLEKKIVDKGVNDYR 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2623587679 216 KADELAIQKASSTLEELAALHDPDMIAGGH--DKISRLGNSNVNSSLGSQWAKadRVAGMDKAAKEAMDLHGPDAKMNVE 293
Cdd:pfam15604  75 EDPIQAEKKAAEALKSLAALHEPDQVAGGQlsVDIIGMGDKSVNSSIGSQWKT--RLSRLDEKAKSAAADGKGSVYLNVR 152
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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