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Conserved domains on  [gi|2630039756|ref|WP_321078994|]
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FtsX-like permease family protein [Candidatus Cryptobacteroides sp.]

Protein Classification

ABC transporter permease( domain architecture ID 11468417)

ABC transporter permease is the transmembrane subunit found in a periplasmic binding protein (PBP)-dependent ABC transport system, which may be involved in the transport of one or more from a variety of substrates including sugars, ions, amino acids, and peptides, among others

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
LolE COG4591
ABC-type transport system involved in lipoprotein release, permease component LolC [Cell wall ...
118-393 3.78e-25

ABC-type transport system involved in lipoprotein release, permease component LolC [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 443648 [Multi-domain]  Cd Length: 283  Bit Score: 103.46  E-value: 3.78e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2630039756 118 SVAAGSDsvklGVSIPSRLATLLGLSPGDRMLTYFIGEAVKVRNFNVVSVYEGIMDNSDELVVLADIKDLQRLNGWDeNE 197
Cdd:COG4591    28 GVAKASD----EVVLGEGLAKKLGLKVGDTITLISPDGSPKTRRFTVVGIFESGGYELDGSLVYVPLETAQELLGLG-DQ 102
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2630039756 198 VSMLEVSLAPHARDAASMSRITAEIGEIVLerqgddedtlipTSVMDRYPQIFDWLSLLDFNVFVILILMTVVAGFNMVS 277
Cdd:COG4591   103 VSGILVKLKDGADAEAVAAALEAALPGLEV------------KTWRELNAALFSALKTEKLILLLILLLILLVAAFNIVN 170
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2630039756 278 GLLIMLFRNIPTIGTLKSLGMTDRMIAKVFLRVSSKVVLKGLLAGNALALAFCLIQGRTHLLRLNpenyFVSFVPVHVNV 357
Cdd:COG4591   171 TLLMSVLERTREIGILKALGASRRQIRRIFLLEGLLLGLIGGLLGLLLGLLLALLLNALLGILLP----FIFALPVSLSP 246
                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 2630039756 358 PAVIAADIAAFAVILLILLIPCLFISRIDPSKTVRA 393
Cdd:COG4591   247 SDVLLALLLALLISLLASLYPARRAARLDPVEALRG 282
 
Name Accession Description Interval E-value
LolE COG4591
ABC-type transport system involved in lipoprotein release, permease component LolC [Cell wall ...
118-393 3.78e-25

ABC-type transport system involved in lipoprotein release, permease component LolC [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443648 [Multi-domain]  Cd Length: 283  Bit Score: 103.46  E-value: 3.78e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2630039756 118 SVAAGSDsvklGVSIPSRLATLLGLSPGDRMLTYFIGEAVKVRNFNVVSVYEGIMDNSDELVVLADIKDLQRLNGWDeNE 197
Cdd:COG4591    28 GVAKASD----EVVLGEGLAKKLGLKVGDTITLISPDGSPKTRRFTVVGIFESGGYELDGSLVYVPLETAQELLGLG-DQ 102
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2630039756 198 VSMLEVSLAPHARDAASMSRITAEIGEIVLerqgddedtlipTSVMDRYPQIFDWLSLLDFNVFVILILMTVVAGFNMVS 277
Cdd:COG4591   103 VSGILVKLKDGADAEAVAAALEAALPGLEV------------KTWRELNAALFSALKTEKLILLLILLLILLVAAFNIVN 170
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2630039756 278 GLLIMLFRNIPTIGTLKSLGMTDRMIAKVFLRVSSKVVLKGLLAGNALALAFCLIQGRTHLLRLNpenyFVSFVPVHVNV 357
Cdd:COG4591   171 TLLMSVLERTREIGILKALGASRRQIRRIFLLEGLLLGLIGGLLGLLLGLLLALLLNALLGILLP----FIFALPVSLSP 246
                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 2630039756 358 PAVIAADIAAFAVILLILLIPCLFISRIDPSKTVRA 393
Cdd:COG4591   247 SDVLLALLLALLISLLASLYPARRAARLDPVEALRG 282
FtsX pfam02687
FtsX-like permease family; This is a family of predicted permeases and hypothetical ...
261-308 8.29e-03

FtsX-like permease family; This is a family of predicted permeases and hypothetical transmembrane proteins. Swiss:P57382 has been shown to transport lipids targeted to the outer membrane across the inner membrane. Both Swiss:P57382 and Swiss:O54500 have been shown to require ATP. This region contains three transmembrane helices.


Pssm-ID: 460652 [Multi-domain]  Cd Length: 120  Bit Score: 36.07  E-value: 8.29e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 2630039756 261 FVILILMTVVAGFNMVSGLLIMLFRNIPTIGTLKSLGMTDRMIAKVFL 308
Cdd:pfam02687   1 ILFSLLILLLAVLIILLLLSISISERRREIGILRALGASRKQIFKLLL 48
 
Name Accession Description Interval E-value
LolE COG4591
ABC-type transport system involved in lipoprotein release, permease component LolC [Cell wall ...
118-393 3.78e-25

ABC-type transport system involved in lipoprotein release, permease component LolC [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443648 [Multi-domain]  Cd Length: 283  Bit Score: 103.46  E-value: 3.78e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2630039756 118 SVAAGSDsvklGVSIPSRLATLLGLSPGDRMLTYFIGEAVKVRNFNVVSVYEGIMDNSDELVVLADIKDLQRLNGWDeNE 197
Cdd:COG4591    28 GVAKASD----EVVLGEGLAKKLGLKVGDTITLISPDGSPKTRRFTVVGIFESGGYELDGSLVYVPLETAQELLGLG-DQ 102
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2630039756 198 VSMLEVSLAPHARDAASMSRITAEIGEIVLerqgddedtlipTSVMDRYPQIFDWLSLLDFNVFVILILMTVVAGFNMVS 277
Cdd:COG4591   103 VSGILVKLKDGADAEAVAAALEAALPGLEV------------KTWRELNAALFSALKTEKLILLLILLLILLVAAFNIVN 170
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2630039756 278 GLLIMLFRNIPTIGTLKSLGMTDRMIAKVFLRVSSKVVLKGLLAGNALALAFCLIQGRTHLLRLNpenyFVSFVPVHVNV 357
Cdd:COG4591   171 TLLMSVLERTREIGILKALGASRRQIRRIFLLEGLLLGLIGGLLGLLLGLLLALLLNALLGILLP----FIFALPVSLSP 246
                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 2630039756 358 PAVIAADIAAFAVILLILLIPCLFISRIDPSKTVRA 393
Cdd:COG4591   247 SDVLLALLLALLISLLASLYPARRAARLDPVEALRG 282
FtsX pfam02687
FtsX-like permease family; This is a family of predicted permeases and hypothetical ...
261-308 8.29e-03

FtsX-like permease family; This is a family of predicted permeases and hypothetical transmembrane proteins. Swiss:P57382 has been shown to transport lipids targeted to the outer membrane across the inner membrane. Both Swiss:P57382 and Swiss:O54500 have been shown to require ATP. This region contains three transmembrane helices.


Pssm-ID: 460652 [Multi-domain]  Cd Length: 120  Bit Score: 36.07  E-value: 8.29e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 2630039756 261 FVILILMTVVAGFNMVSGLLIMLFRNIPTIGTLKSLGMTDRMIAKVFL 308
Cdd:pfam02687   1 ILFSLLILLLAVLIILLLLSISISERRREIGILRALGASRKQIFKLLL 48
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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