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Conserved domains on  [gi|2647465658|ref|WP_324232632|]
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DUF4350 domain-containing protein [Lacibacter sp.]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
YesR COG4225
Rhamnogalacturonyl hydrolase YesR [Carbohydrate transport and metabolism];
35-385 3.46e-144

Rhamnogalacturonyl hydrolase YesR [Carbohydrate transport and metabolism];


:

Pssm-ID: 443369  Cd Length: 336  Bit Score: 421.91  E-value: 3.46e-144
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2647465658  35 PDSLPIGSRTKWSYDMGVVLKGFESLWMRTGNVAYYNSLKNRIDYFVqNDGSikGYELEEYNIDHVNNGKLVLMLYRITG 114
Cdd:COG4225     9 YWDIDPGKFPKWDYTQGVTLYGLLKLAEATGDKKYLDYIKRWFDFFI-DEGN--TYKLPPYNLDDIAPGLALLELYEQTG 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2647465658 115 AEKYKKAAMHLRD-QLRTHPRTNEGGFWHKKIYTNQMWLDGLYMGAPFYAEYAMLFHEDTAFNDIANQFIWMEKHARDPK 193
Cdd:COG4225    86 DPKYLKAADTLADwQLNTQPRTSEGGFWHKKIYPNQLWLDGLYMAVPFLAQYGKLTGDPKYFDDAAKQFLLTTKYLFDPE 165
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2647465658 194 TGLLYHAWDESKQQQwanktTGTSPHFWSRAMGWYADALVDALDYFPADHPKRKDLIAILNRLVNAIEKQQNPtTGLWYD 273
Cdd:COG4225   166 TGLYYHGWDESREQK-----AGGSPAFWGRGNGWVAMALVDLLDLLPEDHPDRPELLALLKEMAAALAKYQDE-SGLWHQ 239
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2647465658 274 VMNyngpgKEKNYFEASASSQFVYAVAKGVRKGYLPATKLAIAKKGYDGIIKRFikEENGQtnLHGTVKVSGLGgkpyrd 353
Cdd:COG4225   240 VLD-----DPGNYLETSATAMFTYALAKGVNKGYLDKKYLPAAEKAWNGLLKKI--DEDGS--LTGVCVGTGLG------ 304
                         330       340       350
                  ....*....|....*....|....*....|..
gi 2647465658 354 GSFAYYMSEDVIVNDPKGVGAFLLAAGEMEQL 385
Cdd:COG4225   305 GSLEYYISEPIRTNDPYGVGPFLLAGSEMLKL 336
DUF4350 pfam14258
Domain of unknown function (DUF4350); This domain family is found in bacteria, archaea, and is ...
428-610 3.53e-10

Domain of unknown function (DUF4350); This domain family is found in bacteria, archaea, and is approximately 170 to 200 amino acids in length. This domain is part of the glutaminase superfamily, suggesting it may have an enzymatic function. The domain is founded between two transmembrane helix domains giving it a membrane localization.


:

Pssm-ID: 464118 [Multi-domain]  Cd Length: 181  Bit Score: 59.40  E-value: 3.53e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2647465658 428 GYYTWGTIFERYGATLKSLDVAPTASNlSKASVYVIVDPDHvrdnpqpnYVTASDVTAISNWVKAGGVLILLANDSNNCD 507
Cdd:pfam14258   8 GTSALAELLEEQGVDVERWRRPLDDLE-GPDGTLLVIAPDF--------GLSPEEAEALLEWVEAGGTLVLAAPNPSGDL 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2647465658 508 LKHFNLlankfGITFTDNSLNMVKNDTYVqGEVLPGANNPVFKTTKKMFLKEISELKVKAPAKTIVTKDHAAiiAVAKYG 587
Cdd:pfam14258  79 LDALGP-----GVRFAGALLDDEQLATPP-RCDLPEAARAGTITLGEVLAGTARLCYGDDLGAALLDSDGPL--RSLQVG 150
                         170       180
                  ....*....|....*....|....*..
gi 2647465658 588 KGTVFAVGDPWIY-NEYI---DNRKLL 610
Cdd:pfam14258 151 KGEITVLGDPSLFtNAMLleeGNAALA 177
 
Name Accession Description Interval E-value
YesR COG4225
Rhamnogalacturonyl hydrolase YesR [Carbohydrate transport and metabolism];
35-385 3.46e-144

Rhamnogalacturonyl hydrolase YesR [Carbohydrate transport and metabolism];


Pssm-ID: 443369  Cd Length: 336  Bit Score: 421.91  E-value: 3.46e-144
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2647465658  35 PDSLPIGSRTKWSYDMGVVLKGFESLWMRTGNVAYYNSLKNRIDYFVqNDGSikGYELEEYNIDHVNNGKLVLMLYRITG 114
Cdd:COG4225     9 YWDIDPGKFPKWDYTQGVTLYGLLKLAEATGDKKYLDYIKRWFDFFI-DEGN--TYKLPPYNLDDIAPGLALLELYEQTG 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2647465658 115 AEKYKKAAMHLRD-QLRTHPRTNEGGFWHKKIYTNQMWLDGLYMGAPFYAEYAMLFHEDTAFNDIANQFIWMEKHARDPK 193
Cdd:COG4225    86 DPKYLKAADTLADwQLNTQPRTSEGGFWHKKIYPNQLWLDGLYMAVPFLAQYGKLTGDPKYFDDAAKQFLLTTKYLFDPE 165
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2647465658 194 TGLLYHAWDESKQQQwanktTGTSPHFWSRAMGWYADALVDALDYFPADHPKRKDLIAILNRLVNAIEKQQNPtTGLWYD 273
Cdd:COG4225   166 TGLYYHGWDESREQK-----AGGSPAFWGRGNGWVAMALVDLLDLLPEDHPDRPELLALLKEMAAALAKYQDE-SGLWHQ 239
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2647465658 274 VMNyngpgKEKNYFEASASSQFVYAVAKGVRKGYLPATKLAIAKKGYDGIIKRFikEENGQtnLHGTVKVSGLGgkpyrd 353
Cdd:COG4225   240 VLD-----DPGNYLETSATAMFTYALAKGVNKGYLDKKYLPAAEKAWNGLLKKI--DEDGS--LTGVCVGTGLG------ 304
                         330       340       350
                  ....*....|....*....|....*....|..
gi 2647465658 354 GSFAYYMSEDVIVNDPKGVGAFLLAAGEMEQL 385
Cdd:COG4225   305 GSLEYYISEPIRTNDPYGVGPFLLAGSEMLKL 336
Glyco_hydro_88 pfam07470
Glycosyl Hydrolase Family 88; Unsaturated glucuronyl hydrolase catalyzes the hydrolytic ...
22-385 2.22e-99

Glycosyl Hydrolase Family 88; Unsaturated glucuronyl hydrolase catalyzes the hydrolytic release of unsaturated glucuronic acids from oligosaccharides (EC:3.2.1.-) produced by the reactions of polysaccharide lyases.


Pssm-ID: 429478  Cd Length: 345  Bit Score: 306.99  E-value: 2.22e-99
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2647465658  22 YSEKVAATVDKIWPDSLPI--GSRTKWSYDMGVVLKGFESLWMRTGNVAYYNSLKNRIDYFVQNDGSIkgyeLEEYNIDH 99
Cdd:pfam07470   1 YIDRVAGSFMKRYPDGKVIdlPPDNRWDWTNGVFLYGMLEAYEATGDKEYLDYLKAWADSLIDEGGKI----LTPYNLDD 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2647465658 100 VNNGKLVLMLYRITGAEKYKKAAMHLRD-QLRTHPRTNEGGFWHKKIYTNQMWLDGLYMGAPFYAEYAMLFHEDTAFNDI 178
Cdd:pfam07470  77 INIGLTLLDLYEHTGDERYIQAAIELADwVLATPPRTSEGGFWHKDIYPHQMWLDGLFMAGPFLAKYGKLTNEPKYLDEA 156
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2647465658 179 ANQFIWMEKHARDPKTGLLYHAWDESKQQQWANKttgtsphFWSRAMGWYADALVDALDYFPADHPKRKDLIAILNRLVN 258
Cdd:pfam07470 157 VYQFLLTRRHLYDPETGLYYHGWDESGTEPWADP-------FWARGNGWYAMALADVLELLPEKHPARQELINILRDLVK 229
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2647465658 259 AIEKQQNPtTGLWYDVMNyngPGKEKNYFEASASSQFVYAVAKGVRKGYLPATKLAIAKKGYDGIIKRFIkEENGQTNLH 338
Cdd:pfam07470 230 ALAKYQDE-SGLWHQSLD---DPDRDSYLETSASAGFVYALAKGVNKGYLDKKYLPVAQKAWKALLKNFV-DEDGQLGVV 304
                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*..
gi 2647465658 339 GTVKVSGLGGKpyrdgsfAYYMSEDVIVNDPKGVGAFLLAAGEMEQL 385
Cdd:pfam07470 305 QICGGTGIGGD-------DYYRSVPYNSNDPYGVGAFLLASTEYLRL 344
DUF4350 pfam14258
Domain of unknown function (DUF4350); This domain family is found in bacteria, archaea, and is ...
428-610 3.53e-10

Domain of unknown function (DUF4350); This domain family is found in bacteria, archaea, and is approximately 170 to 200 amino acids in length. This domain is part of the glutaminase superfamily, suggesting it may have an enzymatic function. The domain is founded between two transmembrane helix domains giving it a membrane localization.


Pssm-ID: 464118 [Multi-domain]  Cd Length: 181  Bit Score: 59.40  E-value: 3.53e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2647465658 428 GYYTWGTIFERYGATLKSLDVAPTASNlSKASVYVIVDPDHvrdnpqpnYVTASDVTAISNWVKAGGVLILLANDSNNCD 507
Cdd:pfam14258   8 GTSALAELLEEQGVDVERWRRPLDDLE-GPDGTLLVIAPDF--------GLSPEEAEALLEWVEAGGTLVLAAPNPSGDL 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2647465658 508 LKHFNLlankfGITFTDNSLNMVKNDTYVqGEVLPGANNPVFKTTKKMFLKEISELKVKAPAKTIVTKDHAAiiAVAKYG 587
Cdd:pfam14258  79 LDALGP-----GVRFAGALLDDEQLATPP-RCDLPEAARAGTITLGEVLAGTARLCYGDDLGAALLDSDGPL--RSLQVG 150
                         170       180
                  ....*....|....*....|....*..
gi 2647465658 588 KGTVFAVGDPWIY-NEYI---DNRKLL 610
Cdd:pfam14258 151 KGEITVLGDPSLFtNAMLleeGNAALA 177
 
Name Accession Description Interval E-value
YesR COG4225
Rhamnogalacturonyl hydrolase YesR [Carbohydrate transport and metabolism];
35-385 3.46e-144

Rhamnogalacturonyl hydrolase YesR [Carbohydrate transport and metabolism];


Pssm-ID: 443369  Cd Length: 336  Bit Score: 421.91  E-value: 3.46e-144
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2647465658  35 PDSLPIGSRTKWSYDMGVVLKGFESLWMRTGNVAYYNSLKNRIDYFVqNDGSikGYELEEYNIDHVNNGKLVLMLYRITG 114
Cdd:COG4225     9 YWDIDPGKFPKWDYTQGVTLYGLLKLAEATGDKKYLDYIKRWFDFFI-DEGN--TYKLPPYNLDDIAPGLALLELYEQTG 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2647465658 115 AEKYKKAAMHLRD-QLRTHPRTNEGGFWHKKIYTNQMWLDGLYMGAPFYAEYAMLFHEDTAFNDIANQFIWMEKHARDPK 193
Cdd:COG4225    86 DPKYLKAADTLADwQLNTQPRTSEGGFWHKKIYPNQLWLDGLYMAVPFLAQYGKLTGDPKYFDDAAKQFLLTTKYLFDPE 165
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2647465658 194 TGLLYHAWDESKQQQwanktTGTSPHFWSRAMGWYADALVDALDYFPADHPKRKDLIAILNRLVNAIEKQQNPtTGLWYD 273
Cdd:COG4225   166 TGLYYHGWDESREQK-----AGGSPAFWGRGNGWVAMALVDLLDLLPEDHPDRPELLALLKEMAAALAKYQDE-SGLWHQ 239
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2647465658 274 VMNyngpgKEKNYFEASASSQFVYAVAKGVRKGYLPATKLAIAKKGYDGIIKRFikEENGQtnLHGTVKVSGLGgkpyrd 353
Cdd:COG4225   240 VLD-----DPGNYLETSATAMFTYALAKGVNKGYLDKKYLPAAEKAWNGLLKKI--DEDGS--LTGVCVGTGLG------ 304
                         330       340       350
                  ....*....|....*....|....*....|..
gi 2647465658 354 GSFAYYMSEDVIVNDPKGVGAFLLAAGEMEQL 385
Cdd:COG4225   305 GSLEYYISEPIRTNDPYGVGPFLLAGSEMLKL 336
Glyco_hydro_88 pfam07470
Glycosyl Hydrolase Family 88; Unsaturated glucuronyl hydrolase catalyzes the hydrolytic ...
22-385 2.22e-99

Glycosyl Hydrolase Family 88; Unsaturated glucuronyl hydrolase catalyzes the hydrolytic release of unsaturated glucuronic acids from oligosaccharides (EC:3.2.1.-) produced by the reactions of polysaccharide lyases.


Pssm-ID: 429478  Cd Length: 345  Bit Score: 306.99  E-value: 2.22e-99
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2647465658  22 YSEKVAATVDKIWPDSLPI--GSRTKWSYDMGVVLKGFESLWMRTGNVAYYNSLKNRIDYFVQNDGSIkgyeLEEYNIDH 99
Cdd:pfam07470   1 YIDRVAGSFMKRYPDGKVIdlPPDNRWDWTNGVFLYGMLEAYEATGDKEYLDYLKAWADSLIDEGGKI----LTPYNLDD 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2647465658 100 VNNGKLVLMLYRITGAEKYKKAAMHLRD-QLRTHPRTNEGGFWHKKIYTNQMWLDGLYMGAPFYAEYAMLFHEDTAFNDI 178
Cdd:pfam07470  77 INIGLTLLDLYEHTGDERYIQAAIELADwVLATPPRTSEGGFWHKDIYPHQMWLDGLFMAGPFLAKYGKLTNEPKYLDEA 156
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2647465658 179 ANQFIWMEKHARDPKTGLLYHAWDESKQQQWANKttgtsphFWSRAMGWYADALVDALDYFPADHPKRKDLIAILNRLVN 258
Cdd:pfam07470 157 VYQFLLTRRHLYDPETGLYYHGWDESGTEPWADP-------FWARGNGWYAMALADVLELLPEKHPARQELINILRDLVK 229
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2647465658 259 AIEKQQNPtTGLWYDVMNyngPGKEKNYFEASASSQFVYAVAKGVRKGYLPATKLAIAKKGYDGIIKRFIkEENGQTNLH 338
Cdd:pfam07470 230 ALAKYQDE-SGLWHQSLD---DPDRDSYLETSASAGFVYALAKGVNKGYLDKKYLPVAQKAWKALLKNFV-DEDGQLGVV 304
                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*..
gi 2647465658 339 GTVKVSGLGGKpyrdgsfAYYMSEDVIVNDPKGVGAFLLAAGEMEQL 385
Cdd:pfam07470 305 QICGGTGIGGD-------DYYRSVPYNSNDPYGVGAFLLASTEYLRL 344
DUF4350 pfam14258
Domain of unknown function (DUF4350); This domain family is found in bacteria, archaea, and is ...
428-610 3.53e-10

Domain of unknown function (DUF4350); This domain family is found in bacteria, archaea, and is approximately 170 to 200 amino acids in length. This domain is part of the glutaminase superfamily, suggesting it may have an enzymatic function. The domain is founded between two transmembrane helix domains giving it a membrane localization.


Pssm-ID: 464118 [Multi-domain]  Cd Length: 181  Bit Score: 59.40  E-value: 3.53e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2647465658 428 GYYTWGTIFERYGATLKSLDVAPTASNlSKASVYVIVDPDHvrdnpqpnYVTASDVTAISNWVKAGGVLILLANDSNNCD 507
Cdd:pfam14258   8 GTSALAELLEEQGVDVERWRRPLDDLE-GPDGTLLVIAPDF--------GLSPEEAEALLEWVEAGGTLVLAAPNPSGDL 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2647465658 508 LKHFNLlankfGITFTDNSLNMVKNDTYVqGEVLPGANNPVFKTTKKMFLKEISELKVKAPAKTIVTKDHAAiiAVAKYG 587
Cdd:pfam14258  79 LDALGP-----GVRFAGALLDDEQLATPP-RCDLPEAARAGTITLGEVLAGTARLCYGDDLGAALLDSDGPL--RSLQVG 150
                         170       180
                  ....*....|....*....|....*..
gi 2647465658 588 KGTVFAVGDPWIY-NEYI---DNRKLL 610
Cdd:pfam14258 151 KGEITVLGDPSLFtNAMLleeGNAALA 177
YihS COG2942
Mannose or cellobiose epimerase, N-acyl-D-glucosamine 2-epimerase family [Carbohydrate ...
108-203 9.49e-04

Mannose or cellobiose epimerase, N-acyl-D-glucosamine 2-epimerase family [Carbohydrate transport and metabolism];


Pssm-ID: 442185  Cd Length: 380  Bit Score: 41.78  E-value: 9.49e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2647465658 108 MLYRITGAEKYKKAAMHLRDQLRTHPRTNEGGFWHkkiytnqmWL---DG--------LYMGApF----YAEYAMLFHED 172
Cdd:COG2942    58 LAYLLLGRPEYLELAEHGLDFLREHFRDPEHGGWY--------WSldaDGkplddrkqAYGHA-FallaLAEAYRATGDP 128
                          90       100       110
                  ....*....|....*....|....*....|.
gi 2647465658 173 TAFNDIANQFIWMEKHARDPKTGLLYHAWDE 203
Cdd:COG2942   129 EALELAKETFELLERRFWDPEHGGYAEAFDR 159
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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