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Conserved domains on  [gi|2648298663|ref|WP_324449872|]
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leucine-rich repeat domain-containing protein [Thermoclostridium caenicola]

Protein Classification

leucine-rich repeat domain-containing protein( domain architecture ID 11469232)

leucine-rich repeat (LRR) domain-containing protein may participate in protein-protein interactions

Gene Ontology:  GO:0005515
PubMed:  11751054|7583641|14747988
SCOP:  4003523

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
85-397 7.61e-38

Leucine-rich repeat (LRR) protein [Transcription];


:

Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 141.22  E-value: 7.61e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2648298663  85 DFIGKTEGAILSTDLEEITDIMIQGTAGRMDDSVNGDVIGINSQEYTGFGEIQSLDDLRLLPDLESLLVSDKHIDDISFL 164
Cdd:COG4886     7 SLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLL 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2648298663 165 KDLHNLFGL-SLSNSNISDIGTLEKLKNLGVLFLSQNRISDISP-LRNLTELSILELWSNQITDI-SPLSGLEKLWLLKL 241
Cdd:COG4886    87 LGLTDLGDLtNLTELDLSGNEELSNLTNLESLDLSGNQLTDLPEeLANLTNLKELDLSNNQLTDLpEPLGNLTNLKSLDL 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2648298663 242 GDNQISDIS-PLKKLTMLEQLYLDANQISDIS-PLKGLANLKVLYLSGNQIRNIS-SLKDLANLEYLFLADNQISDISAL 318
Cdd:COG4886   167 SNNQLTDLPeELGNLTNLKELDLSNNQITDLPePLGNLTNLEELDLSGNQLTDLPePLANLTNLETLDLSNNQLTDLPEL 246

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2648298663 319 KDLHKLGVLNLSNNQISDIGPLAGLTNLQALALDGNQIRDLSPLKGLTNLKYLDLTNNPVGEQQIRELKEALPDIEIEY 397
Cdd:COG4886   247 GNLTNLEELDLSNNQLTDLPPLANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLL 325
 
Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
85-397 7.61e-38

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 141.22  E-value: 7.61e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2648298663  85 DFIGKTEGAILSTDLEEITDIMIQGTAGRMDDSVNGDVIGINSQEYTGFGEIQSLDDLRLLPDLESLLVSDKHIDDISFL 164
Cdd:COG4886     7 SLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLL 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2648298663 165 KDLHNLFGL-SLSNSNISDIGTLEKLKNLGVLFLSQNRISDISP-LRNLTELSILELWSNQITDI-SPLSGLEKLWLLKL 241
Cdd:COG4886    87 LGLTDLGDLtNLTELDLSGNEELSNLTNLESLDLSGNQLTDLPEeLANLTNLKELDLSNNQLTDLpEPLGNLTNLKSLDL 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2648298663 242 GDNQISDIS-PLKKLTMLEQLYLDANQISDIS-PLKGLANLKVLYLSGNQIRNIS-SLKDLANLEYLFLADNQISDISAL 318
Cdd:COG4886   167 SNNQLTDLPeELGNLTNLKELDLSNNQITDLPePLGNLTNLEELDLSGNQLTDLPePLANLTNLETLDLSNNQLTDLPEL 246

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2648298663 319 KDLHKLGVLNLSNNQISDIGPLAGLTNLQALALDGNQIRDLSPLKGLTNLKYLDLTNNPVGEQQIRELKEALPDIEIEY 397
Cdd:COG4886   247 GNLTNLEELDLSNNQLTDLPPLANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLL 325
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 173-335 6.28e-31

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 117.58  E-value: 6.28e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2648298663 173 LSLSNSNISDIGTLEKLKNLGVLFLSQNRISDISPLRNLTELSILELWSNQITDISPLSGLEKLWLLKLGDNQISDISPL 252
Cdd:cd21340     7 LYLNDKNITKIDNLSLCKNLKVLYLYDNKITKIENLEFLTNLTHLYLQNNQIEKIENLENLVNLKKLYLGGNRISVVEGL 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2648298663 253 KKLTMLEQLYLDANQ-------ISDISPLKGLAN-LKVLYLSGNQIRNISSLKDLANLEYLFLADNQISDISALKDL--- 321
Cdd:cd21340    87 ENLTNLEELHIENQRlppgeklTFDPRSLAALSNsLRVLNISGNNIDSLEPLAPLRNLEQLDASNNQISDLEELLDLlss 166

                         170
                  ....*....|....*
gi 2648298663 322 -HKLGVLNLSNNQIS 335
Cdd:cd21340   167 wPSLRELDLTGNPVC 181
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 159-376 8.25e-11

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 63.71  E-value: 8.25e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2648298663 159 DDISFLKdlHNLFGLSLSNSNISDIGTLEKLKNLGVLFLSQNRISDISPLR--NLTELSILELWSNQITDISPLS--GLE 234
Cdd:PLN00113  111 DDIFTTS--SSLRYLNLSNNNFTGSIPRGSIPNLETLDLSNNMLSGEIPNDigSFSSLKVLDLGGNVLVGKIPNSltNLT 188

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2648298663 235 KLWLLKLGDNQISDISP--LKKLTMLEQLYLDANQIS-----DISPLKGLANLKVLY--LSGnQIRniSSLKDLANLEYL 305
Cdd:PLN00113  189 SLEFLTLASNQLVGQIPreLGQMKSLKWIYLGYNNLSgeipyEIGGLTSLNHLDLVYnnLTG-PIP--SSLGNLKNLQYL 265

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2648298663 306 FLADNQISDI--SALKDLHKLGVLNLSNNQISDIGP--LAGLTNLQALALDGNQIRDLSP--LKGLTNLKYLDLTNN 376
Cdd:PLN00113  266 FLYQNKLSGPipPSIFSLQKLISLDLSDNSLSGEIPelVIQLQNLEILHLFSNNFTGKIPvaLTSLPRLQVLQLWSN 342
LRR_9 pfam14580
Leucine-rich repeat;
283-382 7.26e-08

Leucine-rich repeat;


Pssm-ID: 405295 [Multi-domain]  Cd Length: 175  Bit Score: 51.69  E-value: 7.26e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2648298663 283 LYLSGNQIRNISSL-KDLANLEYLFLADNQISDISALKDLHKLGVLNLSNNQISDIGPLAG--LTNLQALALDGNQIR-- 357
Cdd:pfam14580  24 LDLRGYKIPIIENLgATLDQFDTIDFSDNEIRKLDGFPLLRRLKTLLLNNNRICRIGEGLGeaLPNLTELILTNNNLQel 103

                          90       100
                  ....*....|....*....|....*.
gi 2648298663 358 -DLSPLKGLTNLKYLDLTNNPVGEQQ 382
Cdd:pfam14580 104 gDLDPLASLKKLTFLSLLRNPVTNKP 129
 
Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
85-397 7.61e-38

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 141.22  E-value: 7.61e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2648298663  85 DFIGKTEGAILSTDLEEITDIMIQGTAGRMDDSVNGDVIGINSQEYTGFGEIQSLDDLRLLPDLESLLVSDKHIDDISFL 164
Cdd:COG4886     7 SLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLL 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2648298663 165 KDLHNLFGL-SLSNSNISDIGTLEKLKNLGVLFLSQNRISDISP-LRNLTELSILELWSNQITDI-SPLSGLEKLWLLKL 241
Cdd:COG4886    87 LGLTDLGDLtNLTELDLSGNEELSNLTNLESLDLSGNQLTDLPEeLANLTNLKELDLSNNQLTDLpEPLGNLTNLKSLDL 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2648298663 242 GDNQISDIS-PLKKLTMLEQLYLDANQISDIS-PLKGLANLKVLYLSGNQIRNIS-SLKDLANLEYLFLADNQISDISAL 318
Cdd:COG4886   167 SNNQLTDLPeELGNLTNLKELDLSNNQITDLPePLGNLTNLEELDLSGNQLTDLPePLANLTNLETLDLSNNQLTDLPEL 246

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2648298663 319 KDLHKLGVLNLSNNQISDIGPLAGLTNLQALALDGNQIRDLSPLKGLTNLKYLDLTNNPVGEQQIRELKEALPDIEIEY 397
Cdd:COG4886   247 GNLTNLEELDLSNNQLTDLPPLANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLL 325
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 173-335 6.28e-31

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 117.58  E-value: 6.28e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2648298663 173 LSLSNSNISDIGTLEKLKNLGVLFLSQNRISDISPLRNLTELSILELWSNQITDISPLSGLEKLWLLKLGDNQISDISPL 252
Cdd:cd21340     7 LYLNDKNITKIDNLSLCKNLKVLYLYDNKITKIENLEFLTNLTHLYLQNNQIEKIENLENLVNLKKLYLGGNRISVVEGL 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2648298663 253 KKLTMLEQLYLDANQ-------ISDISPLKGLAN-LKVLYLSGNQIRNISSLKDLANLEYLFLADNQISDISALKDL--- 321
Cdd:cd21340    87 ENLTNLEELHIENQRlppgeklTFDPRSLAALSNsLRVLNISGNNIDSLEPLAPLRNLEQLDASNNQISDLEELLDLlss 166

                         170
                  ....*....|....*
gi 2648298663 322 -HKLGVLNLSNNQIS 335
Cdd:cd21340   167 wPSLRELDLTGNPVC 181
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
149-397 9.12e-31

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 121.96  E-value: 9.12e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2648298663 149 ESLLVSDKHIDDI-SFLKDLHNLFGLSLSNSNISDIGT-LEKLKNLGVLFLSQNRISDIS-PLRNLTELSILELWSNQIT 225
Cdd:COG4886   116 ESLDLSGNQLTDLpEELANLTNLKELDLSNNQLTDLPEpLGNLTNLKSLDLSNNQLTDLPeELGNLTNLKELDLSNNQIT 195

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2648298663 226 DIS-PLSGLEKLWLLKLGDNQISDIS-PLKKLTMLEQLYLDANQISDISPLKGLANLKVLYLSGNQIRNISSLKDLANLE 303
Cdd:COG4886   196 DLPePLGNLTNLEELDLSGNQLTDLPePLANLTNLETLDLSNNQLTDLPELGNLTNLEELDLSNNQLTDLPPLANLTNLK 275

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2648298663 304 YLFLADNQISDISaLKDLHKLGVLNLSNNQISDIGPLAGLTNLQALALDGNQIRDLSPLKGLTNLKYLDLTNNPVGEQQI 383
Cdd:COG4886   276 TLDLSNNQLTDLK-LKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLL 354

                         250
                  ....*....|....
gi 2648298663 384 RELKEALPDIEIEY 397
Cdd:COG4886   355 LLNLLSLLLTLLLT 368
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 189-378 1.18e-29

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 114.11  E-value: 1.18e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2648298663 189 LKNLGVLFLSQNRISDISPLRNLTELSILELWSNQITDISPLSGLEKLWLLKLGDNQISDISPLKKLTMLEQLYLDANQI 268
Cdd:cd21340     1 LKRITHLYLNDKNITKIDNLSLCKNLKVLYLYDNKITKIENLEFLTNLTHLYLQNNQIEKIENLENLVNLKKLYLGGNRI 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2648298663 269 SDISPLKGLANLKVLYLSgNQirnisslkDLANLEYLFLADNQISDISalkdlHKLGVLNLSNNQISDIGPLAGLTNLQA 348
Cdd:cd21340    81 SVVEGLENLTNLEELHIE-NQ--------RLPPGEKLTFDPRSLAALS-----NSLRVLNISGNNIDSLEPLAPLRNLEQ 146

                         170       180       190
                  ....*....|....*....|....*....|....
gi 2648298663 349 LALDGNQIRDLS----PLKGLTNLKYLDLTNNPV 378
Cdd:cd21340   147 LDASNNQISDLEelldLLSSWPSLRELDLTGNPV 180
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
149-392 4.57e-26

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 108.48  E-value: 4.57e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2648298663 149 ESLLVSDKHIDDI-SFLKDLHNLFGLSLSNSNISDIGT-LEKLKNLGVLFLSQNRISDIS-PLRNLTELSILELWSNQIT 225
Cdd:COG4886   139 KELDLSNNQLTDLpEPLGNLTNLKSLDLSNNQLTDLPEeLGNLTNLKELDLSNNQITDLPePLGNLTNLEELDLSGNQLT 218

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2648298663 226 DIS-PLSGLEKLWLLKLGDNQISDISPLKKLTMLEQLYLDANQISDISPLKGLANLKVLYLSGNQIRNIsSLKDLANLEY 304
Cdd:COG4886   219 DLPePLANLTNLETLDLSNNQLTDLPELGNLTNLEELDLSNNQLTDLPPLANLTNLKTLDLSNNQLTDL-KLKELELLLG 297

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2648298663 305 LFLADNQISDISALKDLHKLGVLNLSNNQISDIGPLAGLTNLQALALDGNQIRDLSPLKGLTNLKYLDLTNNPVGEQQIR 384
Cdd:COG4886   298 LNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEA 377


                  ....*...
gi 2648298663 385 ELKEALPD 392
Cdd:COG4886   378 TLLTLALL 385
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 252-390 1.41e-22

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 94.85  E-value: 1.41e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2648298663 252 LKKLTmleQLYLDANQISDISPLKGLANLKVLYLSGNQIRNISSLKDLANLEYLFLADNQISDISALKDLHKLGVLNLSN 331
Cdd:cd21340     1 LKRIT---HLYLNDKNITKIDNLSLCKNLKVLYLYDNKITKIENLEFLTNLTHLYLQNNQIEKIENLENLVNLKKLYLGG 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2648298663 332 NQISDIGPLAGLTNLQALALD------------------------------GNQIRDLSPLKGLTNLKYLDLTNNPVgeQ 381
Cdd:cd21340    78 NRISVVEGLENLTNLEELHIEnqrlppgekltfdprslaalsnslrvlnisGNNIDSLEPLAPLRNLEQLDASNNQI--S 155


                  ....*....
gi 2648298663 382 QIRELKEAL 390
Cdd:cd21340   156 DLEELLDLL 164
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
149-373 1.47e-19

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 89.61  E-value: 1.47e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2648298663 149 ESLLVSDKHIDDIS-FLKDLHNLFGLSLSNSNISDIG-TLEKLKNLGVLFLSQNRISDIS-PLRNLTELSILELWSNQIT 225
Cdd:COG4886   162 KSLDLSNNQLTDLPeELGNLTNLKELDLSNNQITDLPePLGNLTNLEELDLSGNQLTDLPePLANLTNLETLDLSNNQLT 241

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2648298663 226 DISPLSGLEKLWLLKLGDNQISDISPLKKLTMLEQLYLDANQISDIS--PLKGLANLKVLYLSGNQIRNISSLKDLANLE 303
Cdd:COG4886   242 DLPELGNLTNLEELDLSNNQLTDLPPLANLTNLKTLDLSNNQLTDLKlkELELLLGLNSLLLLLLLLNLLELLILLLLLT 321

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2648298663 304 YLFLADNQISDISALKDLHKLGVLNLSNNQISDIGPLAGLTNLQALALDGNQIRDLSPLKGLTNLKYLDL 373
Cdd:COG4886   322 TLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLALLLLTLLL 391
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
149-376 8.98e-15

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 75.36  E-value: 8.98e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2648298663 149 ESLLVSDKHIDDISF-LKDLHNLFGLSLSNSNISDIG-TLEKLKNLGVLFLSQNRISDISPLRNLTELSILELWSNQITD 226
Cdd:COG4886   185 KELDLSNNQITDLPEpLGNLTNLEELDLSGNQLTDLPePLANLTNLETLDLSNNQLTDLPELGNLTNLEELDLSNNQLTD 264

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2648298663 227 ISPLSGLEKLWLLKLGDNQISDISpLKKLTMLEQLYLDANQISDISPLKGLANLKVLYLSGNQIRNISSLKDLANLEYLF 306
Cdd:COG4886   265 LPPLANLTNLKTLDLSNNQLTDLK-LKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALS 343

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2648298663 307 LADNQISDISALKDLHKLGVLNLSNNQISDIGPLAGLTNLQALALDGNQIRDLSPLKGLTNLKYLDLTNN 376
Cdd:COG4886   344 LSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLALLLLTLLLLLLTTTAGVLLLTLALLDAVNT 413
RNA1 COG5238
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ...
 168-397 3.42e-13

Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444072 [Multi-domain]  Cd Length: 434  Bit Score: 70.59  E-value: 3.42e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2648298663 168 HNLFGLSLSNSNISDIGT------LEKLKNLGVLFLSQNRISD------ISPLRNLTELSILELWSNQITDisplSGLEK 235
Cdd:COG5238   180 NSVETVYLGCNQIGDEGIeelaeaLTQNTTVTTLWLKRNPIGDegaeilAEALKGNKSLTTLDLSNNQIGD----EGVIA 255

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2648298663 236 LW----------LLKLGDNQISD------ISPLKKLTMLEQLYLDANQISD------ISPLKGLANLKVLYLSGNQIRN- 292
Cdd:COG5238   256 LAealknnttveTLYLSGNQIGAegaialAKALQGNTTLTSLDLSVNRIGDegaialAEGLQGNKTLHTLNLAYNGIGAq 335

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2648298663 293 -----ISSLKDLANLEYLFLADNQISDISA------LKDLHKLGVLNLSNNQISDIGPLAGLTNLQAlaldgnqirdlsp 361
Cdd:COG5238   336 gaialAKALQENTTLHSLDLSDNQIGDEGAialakyLEGNTTLRELNLGKNNIGKQGAEALIDALQT------------- 402

                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 2648298663 362 lkglTNLKYLDLTNNPVGEQQIRELKEALPDIEIEY 397
Cdd:COG5238   403 ----NRLHTLILDGNLIGAEAQQRLEQLLERIKSVY 434
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 159-376 8.25e-11

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 63.71  E-value: 8.25e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2648298663 159 DDISFLKdlHNLFGLSLSNSNISDIGTLEKLKNLGVLFLSQNRISDISPLR--NLTELSILELWSNQITDISPLS--GLE 234
Cdd:PLN00113  111 DDIFTTS--SSLRYLNLSNNNFTGSIPRGSIPNLETLDLSNNMLSGEIPNDigSFSSLKVLDLGGNVLVGKIPNSltNLT 188

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2648298663 235 KLWLLKLGDNQISDISP--LKKLTMLEQLYLDANQIS-----DISPLKGLANLKVLY--LSGnQIRniSSLKDLANLEYL 305
Cdd:PLN00113  189 SLEFLTLASNQLVGQIPreLGQMKSLKWIYLGYNNLSgeipyEIGGLTSLNHLDLVYnnLTG-PIP--SSLGNLKNLQYL 265

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2648298663 306 FLADNQISDI--SALKDLHKLGVLNLSNNQISDIGP--LAGLTNLQALALDGNQIRDLSP--LKGLTNLKYLDLTNN 376
Cdd:PLN00113  266 FLYQNKLSGPipPSIFSLQKLISLDLSDNSLSGEIPelVIQLQNLEILHLFSNNFTGKIPvaLTSLPRLQVLQLWSN 342
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
149-352 1.45e-10

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 62.64  E-value: 1.45e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2648298663 149 ESLLVSDKHIDDISF-LKDLHNLFGLSLSNSNISDIGTLEKLKNLGVLFLSQNRISDISPLRNLTELSILELWSNQITDI 227
Cdd:COG4886   208 EELDLSGNQLTDLPEpLANLTNLETLDLSNNQLTDLPELGNLTNLEELDLSNNQLTDLPPLANLTNLKTLDLSNNQLTDL 287

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2648298663 228 S--PLSGLEKLWLLKLGDNQISDISPLKKLTMLEQLYLDANQISDISPLKGLANLKVLYLSGNQIRNISSLKDLANLEYL 305
Cdd:COG4886   288 KlkELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLL 367

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 2648298663 306 FLADNQISDISALKDLHKLGVLNLSNNQISDIGPLAGLTNLQALALD 352
Cdd:COG4886   368 TLGLLGLLEATLLTLALLLLTLLLLLLTTTAGVLLLTLALLDAVNTE 414
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
 186-395 1.51e-10

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 61.99  E-value: 1.51e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2648298663 186 LEKLKNLGVLFLSQN-----RISDISP-LRNLTELSILELWSNQITDI-----SPLSGLEKLWLLK---LGDNQISDISP 251
Cdd:cd00116    19 LPKLLCLQVLRLEGNtlgeeAAKALASaLRPQPSLKELCLSLNETGRIprglqSLLQGLTKGCGLQeldLSDNALGPDGC 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2648298663 252 -----LKKLTMLEQLYLDANQISDiSPLKGLA--------NLKVLYLSGNQIRNISSlKDLAN-------LEYLFLADNQ 311
Cdd:cd00116    99 gvlesLLRSSSLQELKLNNNGLGD-RGLRLLAkglkdlppALEKLVLGRNRLEGASC-EALAKalranrdLKELNLANNG 176

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2648298663 312 ISD------ISALKDLHKLGVLNLSNNQISDIG------PLAGLTNLQALALDGNQIRDL-------SPLKGLTNLKYLD 372
Cdd:cd00116   177 IGDagiralAEGLKANCNLEVLDLNNNGLTDEGasalaeTLASLKSLEVLNLGDNNLTDAgaaalasALLSPNISLLTLS 256

                         250       260
                  ....*....|....*....|...
gi 2648298663 373 LTNNPVGEQQIRELKEALPDIEI 395
Cdd:cd00116   257 LSCNDITDDGAKDLAEVLAEKES 279
LRR_9 pfam14580
Leucine-rich repeat;
283-382 7.26e-08

Leucine-rich repeat;


Pssm-ID: 405295 [Multi-domain]  Cd Length: 175  Bit Score: 51.69  E-value: 7.26e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2648298663 283 LYLSGNQIRNISSL-KDLANLEYLFLADNQISDISALKDLHKLGVLNLSNNQISDIGPLAG--LTNLQALALDGNQIR-- 357
Cdd:pfam14580  24 LDLRGYKIPIIENLgATLDQFDTIDFSDNEIRKLDGFPLLRRLKTLLLNNNRICRIGEGLGeaLPNLTELILTNNNLQel 103

                          90       100
                  ....*....|....*....|....*.
gi 2648298663 358 -DLSPLKGLTNLKYLDLTNNPVGEQQ 382
Cdd:pfam14580 104 gDLDPLASLKKLTFLSLLRNPVTNKP 129
LRR_8 pfam13855
Leucine rich repeat;
279-334 1.47e-07

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 47.90  E-value: 1.47e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2648298663 279 NLKVLYLSGNQIRNI--SSLKDLANLEYLFLADNQISDIS--ALKDLHKLGVLNLSNNQI 334
Cdd:pfam13855   2 NLRSLDLSNNRLTSLddGAFKGLSNLKVLDLSNNLLTTLSpgAFSGLPSLRYLDLSGNRL 61
LRR_8 pfam13855
Leucine rich repeat;
258-312 1.62e-07

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 47.90  E-value: 1.62e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2648298663 258 LEQLYLDANQISDISP--LKGLANLKVLYLSGNQIRNIS--SLKDLANLEYLFLADNQI 312
Cdd:pfam13855   3 LRSLDLSNNRLTSLDDgaFKGLSNLKVLDLSNNLLTTLSpgAFSGLPSLRYLDLSGNRL 61
LRR_8 pfam13855
Leucine rich repeat;
301-356 1.70e-07

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 47.90  E-value: 1.70e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2648298663 301 NLEYLFLADNQISDI--SALKDLHKLGVLNLSNNQISDIGP--LAGLTNLQALALDGNQI 356
Cdd:pfam13855   2 NLRSLDLSNNRLTSLddGAFKGLSNLKVLDLSNNLLTTLSPgaFSGLPSLRYLDLSGNRL 61
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 166-376 3.77e-07

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 52.16  E-value: 3.77e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2648298663 166 DLHNLFGLSLSNSNIS-DIGTL-EKLKNLGVLFLSQNRISDISP--LRNLTELSILELWSNQITDISP--LSGLEKLWLL 239
Cdd:PLN00113  282 SLQKLISLDLSDNSLSgEIPELvIQLQNLEILHLFSNNFTGKIPvaLTSLPRLQVLQLWSNKFSGEIPknLGKHNNLTVL 361

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2648298663 240 KLGDNQISDISP--------LKKLTM------------------LEQLYLDANQISDISPlKGLANLKVLY---LSGNQI 290
Cdd:PLN00113  362 DLSTNNLTGEIPeglcssgnLFKLILfsnslegeipkslgacrsLRRVRLQDNSFSGELP-SEFTKLPLVYfldISNNNL 440

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2648298663 291 R-NISSLK-DLANLEYLFLADNQIS----DISALKDLHKlgvLNLSNNQISDIGP--LAGLTNLQALALDGNQI-----R 357
Cdd:PLN00113  441 QgRINSRKwDMPSLQMLSLARNKFFgglpDSFGSKRLEN---LDLSRNQFSGAVPrkLGSLSELMQLKLSENKLsgeipD 517

                         250
                  ....*....|....*....
gi 2648298663 358 DLSPLKGLTNlkyLDLTNN 376
Cdd:PLN00113  518 ELSSCKKLVS---LDLSHN 533
LRR_4 pfam12799
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a ...
 279-319 4.03e-06

Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains.


Pssm-ID: 463713 [Multi-domain]  Cd Length: 44  Bit Score: 43.39  E-value: 4.03e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 2648298663 279 NLKVLYLSGNQIRNISSLKDLANLEYLFLADN-QISDISALK 319
Cdd:pfam12799   2 NLEVLDLSNNQITDIPPLAKLPNLETLDLSGNnKITDLSDLA 43
LRR_4 pfam12799
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a ...
 301-342 4.81e-06

Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains.


Pssm-ID: 463713 [Multi-domain]  Cd Length: 44  Bit Score: 43.00  E-value: 4.81e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 2648298663 301 NLEYLFLADNQISDISALKDLHKLGVLNLS-NNQISDIGPLAG 342
Cdd:pfam12799   2 NLEVLDLSNNQITDIPPLAKLPNLETLDLSgNNKITDLSDLAN 44
LRR_8 pfam13855
Leucine rich repeat;
323-378 8.62e-06

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 42.90  E-value: 8.62e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2648298663 323 KLGVLNLSNNQISDIGP--LAGLTNLQALALDGNQIRDLSP--LKGLTNLKYLDLTNNPV 378
Cdd:pfam13855   2 NLRSLDLSNNRLTSLDDgaFKGLSNLKVLDLSNNLLTTLSPgaFSGLPSLRYLDLSGNRL 61
LRR_8 pfam13855
Leucine rich repeat;
212-268 1.06e-05

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 42.51  E-value: 1.06e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2648298663 212 TELSILELWSNQITDISP--LSGLEKLWLLKLGDNQISDISP--LKKLTMLEQLYLDANQI 268
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDgaFKGLSNLKVLDLSNNLLTTLSPgaFSGLPSLRYLDLSGNRL 61
LRR_4 pfam12799
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a ...
 323-364 1.79e-05

Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains.


Pssm-ID: 463713 [Multi-domain]  Cd Length: 44  Bit Score: 41.46  E-value: 1.79e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 2648298663 323 KLGVLNLSNNQISDIGPLAGLTNLQALALDGN-QIRDLSPLKG 364
Cdd:pfam12799   2 NLEVLDLSNNQITDIPPLAKLPNLETLDLSGNnKITDLSDLAN 44
LRR_4 pfam12799
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a ...
 190-232 3.39e-05

Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains.


Pssm-ID: 463713 [Multi-domain]  Cd Length: 44  Bit Score: 40.69  E-value: 3.39e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 2648298663 190 KNLGVLFLSQNRISDISPLRNLTELSILELWSN-QITDISPLSG 232
Cdd:pfam12799   1 PNLEVLDLSNNQITDIPPLAKLPNLETLDLSGNnKITDLSDLAN 44
LRR_4 pfam12799
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a ...
 256-297 4.17e-05

Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains.


Pssm-ID: 463713 [Multi-domain]  Cd Length: 44  Bit Score: 40.69  E-value: 4.17e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 2648298663 256 TMLEQLYLDANQISDISPLKGLANLKVLYLSGN-QIRNISSLK 297
Cdd:pfam12799   1 PNLEVLDLSNNQITDIPPLAKLPNLETLDLSGNnKITDLSDLA 43
LRR_8 pfam13855
Leucine rich repeat;
191-246 2.02e-04

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 39.04  E-value: 2.02e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2648298663 191 NLGVLFLSQNRISDISP--LRNLTELSILELWSNQITDISP--LSGLEKLWLLKLGDNQI 246
Cdd:pfam13855   2 NLRSLDLSNNRLTSLDDgaFKGLSNLKVLDLSNNLLTTLSPgaFSGLPSLRYLDLSGNRL 61
LRR_4 pfam12799
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a ...
 344-377 2.22e-04

Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains.


Pssm-ID: 463713 [Multi-domain]  Cd Length: 44  Bit Score: 38.38  E-value: 2.22e-04
                          10        20        30
                  ....*....|....*....|....*....|....
gi 2648298663 344 TNLQALALDGNQIRDLSPLKGLTNLKYLDLTNNP 377
Cdd:pfam12799   1 PNLEVLDLSNNQITDIPPLAKLPNLETLDLSGNN 34
LRR_4 pfam12799
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a ...
 169-210 3.81e-04

Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains.


Pssm-ID: 463713 [Multi-domain]  Cd Length: 44  Bit Score: 38.00  E-value: 3.81e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 2648298663 169 NLFGLSLSNSNISDIGTLEKLKNLGVLFLSQN-RISDISPLRN 210
Cdd:pfam12799   2 NLEVLDLSNNQITDIPPLAKLPNLETLDLSGNnKITDLSDLAN 44
LRR_8 pfam13855
Leucine rich repeat;
173-224 4.80e-04

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 37.89  E-value: 4.80e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2648298663 173 LSLSNSNISDI--GTLEKLKNLGVLFLSQNRISDISP--LRNLTELSILELWSNQI 224
Cdd:pfam13855   6 LDLSNNRLTSLddGAFKGLSNLKVLDLSNNLLTTLSPgaFSGLPSLRYLDLSGNRL 61
LRR_8 pfam13855
Leucine rich repeat;
239-290 6.57e-04

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 37.50  E-value: 6.57e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2648298663 239 LKLGDNQISDISP--LKKLTMLEQLYLDANQISDISP--LKGLANLKVLYLSGNQI 290
Cdd:pfam13855   6 LDLSNNRLTSLDDgaFKGLSNLKVLDLSNNLLTTLSPgaFSGLPSLRYLDLSGNRL 61
LRR_4 pfam12799
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a ...
 239-276 2.07e-03

Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains.


Pssm-ID: 463713 [Multi-domain]  Cd Length: 44  Bit Score: 35.68  E-value: 2.07e-03
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 2648298663 239 LKLGDNQISDISPLKKLTMLEQLYLDAN-QISDISPLKG 276
Cdd:pfam12799   6 LDLSNNQITDIPPLAKLPNLETLDLSGNnKITDLSDLAN 44
LRR_4 pfam12799
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a ...
 212-254 6.02e-03

Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains.


Pssm-ID: 463713 [Multi-domain]  Cd Length: 44  Bit Score: 34.53  E-value: 6.02e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 2648298663 212 TELSILELWSNQITDISPLSGLEKLWLLKL-GDNQISDISPLKK 254
Cdd:pfam12799   1 PNLEVLDLSNNQITDIPPLAKLPNLETLDLsGNNKITDLSDLAN 44
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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