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Conserved domains on  [gi|2672002883|ref|WP_331223487|]
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type II toxin-antitoxin system antitoxin SocA domain-containing protein [Pediococcus acidilactici]

Protein Classification

Panacea domain-containing protein( domain architecture ID 10007595)

Panacea domain-containing protein may function as an antitoxin component in a type II toxin-antitoxin system, neutralizing a toxin that may act as a translation inhibitor, a membrane disruptor, or via some other mechanism.

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
GepA COG3600
Uncharacterized phage-associated protein, contains DUF4065 domain [Mobilome: prophages, ...
89-225 7.09e-33

Uncharacterized phage-associated protein, contains DUF4065 domain [Mobilome: prophages, transposons];


:

Pssm-ID: 442819  Cd Length: 146  Bit Score: 116.23  E-value: 7.09e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2672002883  89 TITAEEIAGFL---QKNVGIS-SNLKIQKLLYFIYSKILILTGNKLFNEPIQAWDYGPVVPEVYSSFK---WNELPSPNI 161
Cdd:COG3600     2 SISALDVANYFlskANEDGGSlTPLKLQKLLYYAQGWHLALYGRPLFDEDFEAWKYGPVVPELYDEYKdfgSNPIPEPKE 81
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2672002883 162 LLNKLVMNKQREViiesIEYILKKYGDRDAFDLIDLTHRvDTPWSKVFKRNE----NRCITDNLIIEY 225
Cdd:COG3600    82 FDDSELSEEEKEI----LDEVWEKYGKYSAWELSELTHS-ESPWKKARKGLGaegsNNVISDEDIKEY 144
 
Name Accession Description Interval E-value
GepA COG3600
Uncharacterized phage-associated protein, contains DUF4065 domain [Mobilome: prophages, ...
89-225 7.09e-33

Uncharacterized phage-associated protein, contains DUF4065 domain [Mobilome: prophages, transposons];


Pssm-ID: 442819  Cd Length: 146  Bit Score: 116.23  E-value: 7.09e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2672002883  89 TITAEEIAGFL---QKNVGIS-SNLKIQKLLYFIYSKILILTGNKLFNEPIQAWDYGPVVPEVYSSFK---WNELPSPNI 161
Cdd:COG3600     2 SISALDVANYFlskANEDGGSlTPLKLQKLLYYAQGWHLALYGRPLFDEDFEAWKYGPVVPELYDEYKdfgSNPIPEPKE 81
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2672002883 162 LLNKLVMNKQREViiesIEYILKKYGDRDAFDLIDLTHRvDTPWSKVFKRNE----NRCITDNLIIEY 225
Cdd:COG3600    82 FDDSELSEEEKEI----LDEVWEKYGKYSAWELSELTHS-ESPWKKARKGLGaegsNNVISDEDIKEY 144
DUF4065 pfam13274
Protein of unknown function (DUF4065); This family of proteins is functionally uncharacterized. ...
111-199 3.89e-13

Protein of unknown function (DUF4065); This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria, archaea and viruses. Proteins in this family are typically between 155 and 202 amino acids in length.


Pssm-ID: 433077  Cd Length: 108  Bit Score: 63.58  E-value: 3.89e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2672002883 111 IQKLLYFIYSKILILTGNKLFNEPIQAWDYGPVVPEVYSSFK--------------WNELPSPNILLNKLVMNKQREVI- 175
Cdd:pfam13274   1 LQKLLYFADGLHLKKYGKPITGDEYEAWKYGPVVPDVYDLIKgyggnpiedsdeefWDEKLEKVDYIEVELLEDGGENDl 80
                          90       100
                  ....*....|....*....|....*...
gi 2672002883 176 ----IESIEYILKKYGDRDAFDLIDLTH 199
Cdd:pfam13274  81 seeeIEILDEVIEKYGDLSADELSELTH 108
 
Name Accession Description Interval E-value
GepA COG3600
Uncharacterized phage-associated protein, contains DUF4065 domain [Mobilome: prophages, ...
89-225 7.09e-33

Uncharacterized phage-associated protein, contains DUF4065 domain [Mobilome: prophages, transposons];


Pssm-ID: 442819  Cd Length: 146  Bit Score: 116.23  E-value: 7.09e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2672002883  89 TITAEEIAGFL---QKNVGIS-SNLKIQKLLYFIYSKILILTGNKLFNEPIQAWDYGPVVPEVYSSFK---WNELPSPNI 161
Cdd:COG3600     2 SISALDVANYFlskANEDGGSlTPLKLQKLLYYAQGWHLALYGRPLFDEDFEAWKYGPVVPELYDEYKdfgSNPIPEPKE 81
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2672002883 162 LLNKLVMNKQREViiesIEYILKKYGDRDAFDLIDLTHRvDTPWSKVFKRNE----NRCITDNLIIEY 225
Cdd:COG3600    82 FDDSELSEEEKEI----LDEVWEKYGKYSAWELSELTHS-ESPWKKARKGLGaegsNNVISDEDIKEY 144
DUF4065 pfam13274
Protein of unknown function (DUF4065); This family of proteins is functionally uncharacterized. ...
111-199 3.89e-13

Protein of unknown function (DUF4065); This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria, archaea and viruses. Proteins in this family are typically between 155 and 202 amino acids in length.


Pssm-ID: 433077  Cd Length: 108  Bit Score: 63.58  E-value: 3.89e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2672002883 111 IQKLLYFIYSKILILTGNKLFNEPIQAWDYGPVVPEVYSSFK--------------WNELPSPNILLNKLVMNKQREVI- 175
Cdd:pfam13274   1 LQKLLYFADGLHLKKYGKPITGDEYEAWKYGPVVPDVYDLIKgyggnpiedsdeefWDEKLEKVDYIEVELLEDGGENDl 80
                          90       100
                  ....*....|....*....|....*...
gi 2672002883 176 ----IESIEYILKKYGDRDAFDLIDLTH 199
Cdd:pfam13274  81 seeeIEILDEVIEKYGDLSADELSELTH 108
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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