|
Name |
Accession |
Description |
Interval |
E-value |
| thiolase |
cd00751 |
Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of ... |
5-364 |
0e+00 |
|
Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and eukaryotes (cytosol, microbodies and mitochondria). There are 2 functional different classes: thiolase-I (3-ketoacyl-CoA thiolase) and thiolase-II (acetoacetyl-CoA thiolase). Thiolase-I can cleave longer fatty acid molecules and plays an important role in the beta-oxidative degradation of fatty acids. Thiolase-II has a high substrate specificity. Although it can cleave acetoacyl-CoA, its main function is the synthesis of acetoacyl-CoA from two molecules of acetyl-CoA, which gives it importance in several biosynthetic pathways.
Pssm-ID: 238383 [Multi-domain] Cd Length: 386 Bit Score: 513.57 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 5 VIIDALRTPVGRYDGALAEYSAAELGTHVVSNLLSKHENIKSDVEQVIFGNVLQAGNGQNIARQIAIHSGLPNTVPASTI 84
Cdd:cd00751 1 VIVSAVRTPIGRFGGALKDVSADDLGAAVIKALLERAGLDPEEVDDVIMGNVLQAGEGQNPARQAALLAGLPESVPATTV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 85 NEVCGSGMKAVILAKQLLQLGEAEVVIAGGTESMSNAPIIKN------RKTQEETLSMLNDGLVDAFSGISMGIIGETIA 158
Cdd:cd00751 81 NRVCGSGLQAVALAAQSIAAGEADVVVAGGVESMSRAPYLLPkarrggRLGLNTLDGMLDDGLTDPFTGLSMGITAENVA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 159 EQFDISRADQDAFAQNSQEKAVAASQAGIFKEEIVAI------GDVGV--DETPRPSSSLEKLATLRTAFKENGTVTAGN 230
Cdd:cd00751 161 EKYGISREEQDEFALRSHQRAAAAQEAGRFKDEIVPVevpgrkGPVVVdrDEGPRPDTTLEKLAKLKPAFKKDGTVTAGN 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 231 SSPVNDGASAVILATKDYAEKHEIPYLAELVDSTEVGIDPAIMGVSPIEAIKKLINRSELELSDIDLFEINEAFAASSLA 310
Cdd:cd00751 241 ASGINDGAAAVLLMSEEKAKELGLKPLARIVGYAVAGVDPAIMGIGPVPAIPKALKRAGLTLDDIDLIEINEAFAAQALA 320
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....
gi 2676378839 311 VNRELGLNESQVNIYGGAIALGHAIGSSGSKILTTLSYALKREQKRYGIASLCI 364
Cdd:cd00751 321 CLKELGLDPEKVNVNGGAIALGHPLGASGARIVVTLLHELKRRGGRYGLATMCI 374
|
|
| PaaJ |
COG0183 |
Acetyl-CoA acetyltransferase [Lipid transport and metabolism]; Acetyl-CoA acetyltransferase is ... |
1-364 |
0e+00 |
|
Acetyl-CoA acetyltransferase [Lipid transport and metabolism]; Acetyl-CoA acetyltransferase is part of the Pathway/BioSystem: Fatty acid biosynthesis
Pssm-ID: 439953 [Multi-domain] Cd Length: 391 Bit Score: 511.92 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 1 MKEIVIIDALRTPVGRYDGALAEYSAAELGTHVVSNLLSKHENIKSDVEQVIFGNVLQAGNGQNIARQIAIHSGLPNTVP 80
Cdd:COG0183 1 MREVVIVDAVRTPFGRFGGALADVRADDLGAAVIKALLERAGLDPEAVDDVILGCVLQAGQGQNPARQAALLAGLPESVP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 81 ASTINEVCGSGMKAVILAKQLLQLGEAEVVIAGGTESMSNAPIIKNRKTQEETL------SMLNDGLVDAFSGISMGIIG 154
Cdd:COG0183 81 AVTVNRVCGSGLQAVALAAQAIAAGDADVVIAGGVESMSRAPMLLPKARWGYRMnaklvdPMINPGLTDPYTGLSMGETA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 155 ETIAEQFDISRADQDAFAQNSQEKAVAASQAGIFKEEIVAI------GDVGV--DETPRPSSSLEKLATLRTAFKENGTV 226
Cdd:COG0183 161 ENVAERYGISREEQDAFALRSHQRAAAAIAAGRFDDEIVPVevpdrkGEVVVdrDEGPRPDTTLEKLAKLKPAFKKDGTV 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 227 TAGNSSPVNDGASAVILATKDYAEKHEIPYLAELVDSTEVGIDPAIMGVSPIEAIKKLINRSELELSDIDLFEINEAFAA 306
Cdd:COG0183 241 TAGNASGINDGAAALLLMSEEAAKELGLKPLARIVAYAVAGVDPEIMGIGPVPATRKALARAGLTLDDIDLIEINEAFAA 320
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*...
gi 2676378839 307 SSLAVNRELGLNESQVNIYGGAIALGHAIGSSGSKILTTLSYALKREQKRYGIASLCI 364
Cdd:COG0183 321 QVLAVLRELGLDPDKVNVNGGAIALGHPLGASGARILVTLLHELERRGGRYGLATMCI 378
|
|
| PRK05790 |
PRK05790 |
putative acyltransferase; Provisional |
1-364 |
2.17e-169 |
|
putative acyltransferase; Provisional
Pssm-ID: 180261 [Multi-domain] Cd Length: 393 Bit Score: 478.11 E-value: 2.17e-169
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 1 MKEIVIIDALRTPVGRYDGALAEYSAAELGTHVVSNLLSKHENIKSDVEQVIFGNVLQAGNGQNIARQIAIHSGLPNTVP 80
Cdd:PRK05790 1 MKDVVIVSAARTPIGKFGGALKDVSAVELGAIVIKAALERAGVPPEQVDEVIMGQVLQAGAGQNPARQAALKAGLPVEVP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 81 ASTINEVCGSGMKAVILAKQLLQLGEAEVVIAGGTESMSNAPII--KNR---KTQEETL--SMLNDGLVDAFSGISMGII 153
Cdd:PRK05790 81 ALTINKVCGSGLKAVALAAQAIRAGDADIVVAGGQESMSQAPHVlpGSRwgqKMGDVELvdTMIHDGLTDAFNGYHMGIT 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 154 GETIAEQFDISRADQDAFAQNSQEKAVAASQAGIFKEEIVAI------GD---VGVDETPRPSSSLEKLATLRTAFKENG 224
Cdd:PRK05790 161 AENLAEQYGITREEQDEFALASQQKAEAAIKAGRFKDEIVPVtikqrkGDpvvVDTDEHPRPDTTAESLAKLRPAFDKDG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 225 TVTAGNSSPVNDGASAVILATKDYAEKHEIPYLAELVDSTEVGIDPAIMGVSPIEAIKKLINRSELELSDIDLFEINEAF 304
Cdd:PRK05790 241 TVTAGNASGINDGAAAVVVMSEAKAKELGLTPLARIVSYAVAGVDPAIMGIGPVPAIRKALEKAGWSLADLDLIEINEAF 320
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 305 AASSLAVNRELGLNESQVNIYGGAIALGHAIGSSGSKILTTLSYALKREQKRYGIASLCI 364
Cdd:PRK05790 321 AAQALAVEKELGLDPEKVNVNGGAIALGHPIGASGARILVTLLHEMKRRGAKKGLATLCI 380
|
|
| AcCoA-C-Actrans |
TIGR01930 |
acetyl-CoA acetyltransferases; This model represents a large family of enzymes which catalyze ... |
6-364 |
2.10e-153 |
|
acetyl-CoA acetyltransferases; This model represents a large family of enzymes which catalyze the thiolysis of a linear fatty acid CoA (or acetoacetyl-CoA) using a second CoA molecule to produce acetyl-CoA and a CoA-ester product two carbons shorter (or, alternatively, the condensation of two molecules of acetyl-CoA to produce acetoacetyl-CoA and CoA). This enzyme is also known as "thiolase", "3-ketoacyl-CoA thiolase", "beta-ketothiolase" and "Fatty oxidation complex beta subunit". When catalyzing the degradative reaction on fatty acids the corresponding EC number is 2.3.1.16. The condensation reaction corresponds to 2.3.1.9. Note that the enzymes which catalyze the condensation are generally not involved in fatty acid biosynthesis, which is carried out by a decarboxylating condensation of acetyl and malonyl esters of acyl carrier proteins. Rather, this activity may produce acetoacetyl-CoA for pathways such as IPP biosynthesis in the absence of sufficient fatty acid oxidation. [Fatty acid and phospholipid metabolism, Other]
Pssm-ID: 273881 [Multi-domain] Cd Length: 385 Bit Score: 437.43 E-value: 2.10e-153
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 6 IIDALRTPVGRYDGALAEYSAAELGTHVVSNLLSKHENIKSDVEQVIFGNVLQAGNGQNIARQIAIHSGLPNTVPASTIN 85
Cdd:TIGR01930 1 IVAAARTPIGKFGGSLKDVSAEDLGAAVIKELLERNPLDPELIDDVIFGNVLQAGEQQNIARQAALLAGLPESVPAYTVN 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 86 EVCGSGMKAVILAKQLLQLGEAEVVIAGGTESMSNAPIIKNRKTQE-------ETLSMLNDGLVDAFSGISMGIIGETIA 158
Cdd:TIGR01930 81 RQCASGLQAVILAAQLIRAGEADVVVAGGVESMSRVPYGVPRSLRWgvkpgnaELEDARLKDLTDANTGLPMGVTAENLA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 159 EQFDISRADQDAFAQNSQEKAVAASQAGIFKEEIVAIGDVG--------VDETPRPSSSLEKLATLRTAFKENGTVTAGN 230
Cdd:TIGR01930 161 KKYGISREEQDEYALRSHQRAAKAWEEGLFKDEIVPVTVKGrkgpvtvsSDEGIRPNTTLEKLAKLKPAFDPDGTVTAGN 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 231 SSPVNDGASAVILATKDYAEKHEIPYLAELVDSTEVGIDPAIMGVSPIEAIKKLINRSELELSDIDLFEINEAFAASSLA 310
Cdd:TIGR01930 241 SSPLNDGAAALLLMSEEKAKELGLTPLARIVSFAVAGVDPEIMGLGPVPAIPKALKKAGLSISDIDLFEINEAFAAQVLA 320
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....
gi 2676378839 311 VNRELGLNESQVNIYGGAIALGHAIGSSGSKILTTLSYALKREQKRYGIASLCI 364
Cdd:TIGR01930 321 CIKELGLDLEKVNVNGGAIALGHPLGASGARIVTTLLHELKRRGGRYGLATMCI 374
|
|
| PRK08235 |
PRK08235 |
acetyl-CoA C-acetyltransferase; |
1-363 |
5.41e-124 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 181311 [Multi-domain] Cd Length: 393 Bit Score: 362.88 E-value: 5.41e-124
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 1 MKEIVIIDALRTPVGRYDGALAEYSAAELGTHVVSNLLSKHENIKSDVEQVIFGNVLQAGNGQNIARQIAIHSGLPNTVP 80
Cdd:PRK08235 1 MSKTVIVSAARTPFGKFGGSLKDVKATELGGIAIKEALERANVSAEDVEEVIMGTVLQGGQGQIPSRQAARAAGIPWEVQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 81 ASTINEVCGSGMKAVILAKQLLQLGEAEVVIAGGTESMSNAPII------KNRKTQEETLS-MLNDGLVDAFSGISMGII 153
Cdd:PRK08235 81 TETVNKVCASGLRAVTLADQIIRAGDASVIVAGGMESMSNAPYIlpgarwGYRMGDNEVIDlMVADGLTCAFSGVHMGVY 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 154 GETIAEQFDISRADQDAFAQNSQEKAVAASQAGIFKEEIVAI------GD---VGVDETPRPSSSLEKLATLRTAFKENG 224
Cdd:PRK08235 161 GGEVAKELGISREAQDEWAYRSHQRAVSAHEEGRFEEEIVPVtipqrkGDpivVAKDEAPRKDTTIEKLAKLKPVFDKTG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 225 TVTAGNSSPVNDGASAVILATKDYAEKHEIPYLAELVDSTEVGIDPAIMGVSPIEAIKKLINRSELELSDIDLFEINEAF 304
Cdd:PRK08235 241 TITAGNAPGVNDGAAALVLMSEDRAKQEGRKPLATILAHTAIAVEAKDFPRTPGYAINALLEKTGKTVEDIDLFEINEAF 320
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*....
gi 2676378839 305 AASSLAVNRELGLNESQVNIYGGAIALGHAIGSSGSKILTTLSYALKREQKRYGIASLC 363
Cdd:PRK08235 321 AAVALASTEIAGIDPEKVNVNGGAVALGHPIGASGARIIVTLIHELKRRGGGIGIAAIC 379
|
|
| PRK09050 |
PRK09050 |
beta-ketoadipyl CoA thiolase; Validated |
1-364 |
2.26e-121 |
|
beta-ketoadipyl CoA thiolase; Validated
Pssm-ID: 181624 [Multi-domain] Cd Length: 401 Bit Score: 356.57 E-value: 2.26e-121
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 1 MKEIVIIDALRTPVGRYDGALAEYSAAELGTHVVSNLLSKHENIK-SDVEQVIFGNVLQAG-NGQNIARQIAIHSGLPNT 78
Cdd:PRK09050 1 MTEAFICDAIRTPIGRYGGALSSVRADDLGAVPLKALMARNPGVDwEAVDDVIYGCANQAGeDNRNVARMSALLAGLPVS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 79 VPASTINEVCGSGMKAVILAKQLLQLGEAEVVIAGGTESMSNAPII---------KNRKTQEETLS--MLNDGLVDAFSG 147
Cdd:PRK09050 81 VPGTTINRLCGSGMDAVGTAARAIKAGEAELMIAGGVESMSRAPFVmgkadsafsRQAEIFDTTIGwrFVNPLMKAQYGV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 148 ISMGIIGETIAEQFDISRADQDAFAQNSQEKAVAASQAGIFKEEIVAI------GD---VGVDETPRPSSSLEKLATLRT 218
Cdd:PRK09050 161 DSMPETAENVAEDYNISRADQDAFALRSQQRAAAAQAAGFLAEEIVPVtipqkkGDpvvVDRDEHPRPETTLEALAKLKP 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 219 AFKENGTVTAGNSSPVNDGASAVILATKDYAEKHEIPYLAELVDSTEVGIDPAIMGVSPIEAIKKLINRSELELSDIDLF 298
Cdd:PRK09050 241 VFRPDGTVTAGNASGVNDGAAALLLASEAAAKKHGLTPRARILGMATAGVEPRIMGIGPAPATRKLLARLGLTIDQFDVI 320
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2676378839 299 EINEAFAASSLAVNRELGL--NESQVNIYGGAIALGHAIGSSGSKILTTLSYALKREQKRYGIASLCI 364
Cdd:PRK09050 321 ELNEAFAAQGLAVLRQLGLadDDARVNPNGGAIALGHPLGMSGARLVLTALHQLERTGGRYALCTMCI 388
|
|
| PRK05656 |
PRK05656 |
acetyl-CoA C-acetyltransferase; |
1-364 |
1.52e-118 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 168156 Cd Length: 393 Bit Score: 349.19 E-value: 1.52e-118
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 1 MKEIVIIDALRTPVGRYDGALAEYSAAELGTHVVSNLLSKHENIKSDVEQVIFGNVLQAGNGQNIARQIAIHSGLPNTVP 80
Cdd:PRK05656 1 MQDVVIVAATRTAIGSFQGSLANIPAVELGAAVIRRLLEQTGLDPAQVDEVILGQVLTAGAGQNPARQAAIKAGLPHSVP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 81 ASTINEVCGSGMKAVILAKQLLQLGEAEVVIAGGTESMSNAPIIKNRKTQEETL-------SMLNDGLVDAFSGISMGII 153
Cdd:PRK05656 81 AMTLNKVCGSGLKALHLAAQAIRCGDAEVIIAGGQENMSLAPYVLPGARTGLRMghaqlvdSMITDGLWDAFNDYHMGIT 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 154 GETIAEQFDISRADQDAFAQNSQEKAVAASQAGIFKEEIVAI------GD---VGVDETPRPSSSLEKLATLRTAFKENG 224
Cdd:PRK05656 161 AENLVEKYGISREAQDAFAAASQQKAVAAIEAGRFDDEITPIlipqrkGEplaFATDEQPRAGTTAESLAKLKPAFKKDG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 225 TVTAGNSSPVNDGASAVILATKDYAEKHEIPYLAELVDSTEVGIDPAIMGVSPIEAIKKLINRSELELSDIDLFEINEAF 304
Cdd:PRK05656 241 SVTAGNASSLNDGAAAVLLMSAAKAKALGLPVLAKIAAYANAGVDPAIMGIGPVSATRRCLDKAGWSLAELDLIEANEAF 320
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 305 AASSLAVNRELGLNESQVNIYGGAIALGHAIGSSGSKILTTLSYALKREQKRYGIASLCI 364
Cdd:PRK05656 321 AAQSLAVGKELGWDAAKVNVNGGAIALGHPIGASGCRVLVTLLHEMIRRDAKKGLATLCI 380
|
|
| PRK09051 |
PRK09051 |
beta-ketothiolase BktB; |
1-364 |
3.01e-114 |
|
beta-ketothiolase BktB;
Pssm-ID: 181625 [Multi-domain] Cd Length: 394 Bit Score: 338.09 E-value: 3.01e-114
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 1 MKEIVIIDALRTPVGRYDGALAEYSAAELGTHVVSNLLSKHENIKSDVEQVIFGNVLQAG-NGQNIARQIAIHSGLPNTV 79
Cdd:PRK09051 2 MREVVVVSGVRTAIGTFGGSLKDVAPTDLGATVVREALARAGVDPDQVGHVVFGHVIPTEpRDMYLSRVAAINAGVPQET 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 80 PASTINEVCGSGMKAVILAKQLLQLGEAEVVIAGGTESMSNAPIIK------NRKTQEETLSMLNDGLVDAFSGISMGII 153
Cdd:PRK09051 82 PAFNVNRLCGSGLQAIVSAAQAILLGDADVAIGGGAESMSRAPYLLpaarwgARMGDAKLVDMMVGALHDPFGTIHMGVT 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 154 GETIAEQFDISRADQDAFAQNSQEKAVAASQAGIFKEEIVAI------GDV--GVDETPRPSSSLEKLATLRTAF-KENG 224
Cdd:PRK09051 162 AENVAAKYGISREAQDALALESHRRAAAAIAAGYFKDQIVPVeiktrkGEVvfDTDEHVRADTTLEDLAKLKPVFkKENG 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 225 TVTAGNSSPVNDGASAVILATKDYAEKHEIPYLAELVDSTEVGIDPAIMGVSPIEAIKKLINRSELELSDIDLFEINEAF 304
Cdd:PRK09051 242 TVTAGNASGINDGAAAVVLAEADAAEARGLKPLARLVGYAHAGVDPEYMGIGPVPATQKALERAGLTVADLDVIEANEAF 321
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 305 AASSLAVNRELGLNESQVNIYGGAIALGHAIGSSGSKILTTLSYALKREQKRYGIASLCI 364
Cdd:PRK09051 322 AAQACAVTRELGLDPAKVNPNGSGISLGHPVGATGAIITVKALYELQRIGGRYALVTMCI 381
|
|
| PLN02644 |
PLN02644 |
acetyl-CoA C-acetyltransferase |
2-363 |
5.83e-113 |
|
acetyl-CoA C-acetyltransferase
Pssm-ID: 215347 [Multi-domain] Cd Length: 394 Bit Score: 334.75 E-value: 5.83e-113
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 2 KEIVIIDALRTPVGRYDGALAEYSAAELGTHVVSNLLSKHENIKSDVEQVIFGNVLQAGNGQNIARQIAIHSGLPNTVPA 81
Cdd:PLN02644 1 RDVCIVGVARTPIGGFLGSLSSLSATELGSIAIQAALERAGVDPALVQEVFFGNVLSANLGQAPARQAALGAGLPPSTIC 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 82 STINEVCGSGMKAVILAKQLLQLGEAEVVIAGGTESMSNAPIIKNRKTQEETL-------SMLNDGLVDAFSGISMGIIG 154
Cdd:PLN02644 81 TTVNKVCASGMKAVMLAAQSIQLGINDVVVAGGMESMSNAPKYLPEARKGSRLghdtvvdGMLKDGLWDVYNDFGMGVCA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 155 ETIAEQFDISRADQDAFAQNSQEKAVAASQAGIFKEEIVAIGDVG--------VDETPRPSS-SLEKLATLRTAFKEN-G 224
Cdd:PLN02644 161 ELCADQYSISREEQDAYAIQSYERAIAAQEAGAFAWEIVPVEVPGgrgrpsviVDKDEGLGKfDPAKLRKLRPSFKEDgG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 225 TVTAGNSSPVNDGASAVILATKDYAEKHEIPYLAELVDSTEVGIDPAIMGVSPIEAIKKLINRSELELSDIDLFEINEAF 304
Cdd:PLN02644 241 SVTAGNASSISDGAAALVLVSGEKALELGLQVIAKIRGYADAAQAPELFTTAPALAIPKALKHAGLEASQVDYYEINEAF 320
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*....
gi 2676378839 305 AASSLAVNRELGLNESQVNIYGGAIALGHAIGSSGSKILTTLSYALKREQKRYGIASLC 363
Cdd:PLN02644 321 SVVALANQKLLGLDPEKVNVHGGAVSLGHPIGCSGARILVTLLGVLRSKNGKYGVAGIC 379
|
|
| PRK06633 |
PRK06633 |
acetyl-CoA C-acetyltransferase; |
1-364 |
3.89e-109 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 168632 [Multi-domain] Cd Length: 392 Bit Score: 325.06 E-value: 3.89e-109
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 1 MKEIVIIDALRTPVGRYDGALAEYSAAELGTHVVSNLLSKHENIKSDVEQVIFGNVLQAGNGQNIARQIAIHSGLPNTVP 80
Cdd:PRK06633 2 TKPVYITHAKRTAFGSFMGSLSTTPAPMLAAHLIKDILQNSKIDPALVNEVILGQVITGGSGQNPARQTLIHAGIPKEVP 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 81 ASTINEVCGSGMKAVILAKQLLQLGEAEVVIAGGTESMS----NAPIIKNRKTQEETLS--MLNDGLVDAFSGISMGIIG 154
Cdd:PRK06633 82 GYTINKVCGSGLKSVALAANSIMTGDNEIVIAGGQENMSlgmhGSYIRAGAKFGDIKMVdlMQYDGLTDVFSGVFMGITA 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 155 ETIAEQFDISRADQDAFAQNSQEKAVAASQAGIFKEEIVAIgDVGV---------DETPRPSSSLEKLATLRTAFKENGT 225
Cdd:PRK06633 162 ENISKQFNISRQEQDEFALSSHKKAAKAQLAGIFKDEILPI-EVTIkkttslfdhDETVRPDTSLEILSKLRPAFDKNGV 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 226 VTAGNSSPVNDGASAVILATKDYAEKHEIPYLAELVDSTEVGIDPAIMGVSPIEAIKKLINRSELELSDIDLFEINEAFA 305
Cdd:PRK06633 241 VTAGNASSINDGAACLMVVSEEALKKHNLTPLARIVSYASAGVDPSIMGTAPVPASQKALSKAGWSVNDLEVIEVNEAFA 320
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*....
gi 2676378839 306 ASSLAVNRELGLNESQVNIYGGAIALGHAIGSSGSKILTTLSYALKREQKRYGIASLCI 364
Cdd:PRK06633 321 AQSIYVNREMKWDMEKVNINGGAIAIGHPIGASGGRVLITLIHGLRRAKAKKGLVTLCI 379
|
|
| pcaF |
TIGR02430 |
3-oxoadipyl-CoA thiolase; Members of this family are designated beta-ketoadipyl CoA thiolase, ... |
2-364 |
6.14e-108 |
|
3-oxoadipyl-CoA thiolase; Members of this family are designated beta-ketoadipyl CoA thiolase, an enzyme that acts at the end of pathways for the degradation of protocatechuate (from benzoate and related compounds) and of phenylacetic acid.
Pssm-ID: 131483 Cd Length: 400 Bit Score: 322.50 E-value: 6.14e-108
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 2 KEIVIIDALRTPVGRYDGALAEYSAAELGTHVVSNLLSKHENIK-SDVEQVIFGNVLQAG-NGQNIARQIAIHSGLPNTV 79
Cdd:TIGR02430 1 REAYICDAIRTPIGRYGGSLSSVRADDLAAVPIKALLARNPQLDwAAIDDVIYGCANQAGeDNRNVARMAALLAGLPVSV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 80 PASTINEVCGSGMKAVILAKQLLQLGEAEVVIAGGTESMSNAPIIK-------NRKTQEETLSM----LNDGLVDAFSGI 148
Cdd:TIGR02430 81 PGTTVNRLCGSGLDAIGMAARAIKAGEADLLIAGGVESMSRAPFVMgkadsafSRSAKIEDTTIgwrfINPLMKALYGVD 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 149 SMGIIGETIAEQFDISRADQDAFAQNSQEKAVAASQAGIFKEEIVAI------GD---VGVDETPRPSSSLEKLATLRTA 219
Cdd:TIGR02430 161 SMPETAENVAEEFGISREDQDAFALRSQQRTAAAQASGFFAEEIVPVvipqkkGEptvVDQDEHPRPETTLEGLAKLKPV 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 220 FKENGTVTAGNSSPVNDGASAVILATKDYAEKHEIPYLAELVDSTEVGIDPAIMGVSPIEAIKKLINRSELELSDIDLFE 299
Cdd:TIGR02430 241 VRPDGTVTAGNASGVNDGAAALLLASEEAVQRHGLTPRARILAAATAGVEPRIMGIGPVPATQKLLARAGLSIDQFDVIE 320
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2676378839 300 INEAFAASSLAVNRELGL--NESQVNIYGGAIALGHAIGSSGSKILTTLSYALKREQKRYGIASLCI 364
Cdd:TIGR02430 321 LNEAFAAQALAVLRELGLadDDARVNPNGGAIALGHPLGASGARLVLTALRQLERSGGRYALCTMCI 387
|
|
| PRK09052 |
PRK09052 |
acetyl-CoA C-acyltransferase; |
1-364 |
5.92e-107 |
|
acetyl-CoA C-acyltransferase;
Pssm-ID: 181626 [Multi-domain] Cd Length: 399 Bit Score: 319.64 E-value: 5.92e-107
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 1 MKEIVIIDALRTPVGRY-DGALAEYSAAELGTHVVSNLLSKHENI-KSDVEQVIFGNVL-QAGNGQNIARQIAIHSGLPN 77
Cdd:PRK09052 5 LQDAYIVAATRTPVGKApRGMFKNTRPDDLLAHVLRSAVAQVPGLdPKLIEDAIVGCAMpEAEQGLNVARIGALLAGLPN 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 78 TVPASTINEVCGSGMKAVILAKQLLQLGEAEVVIAGGTESMSNAPIIKNRKTQEETLSMLNDGLVDAFSgisMGIIGETI 157
Cdd:PRK09052 85 SVGGVTVNRFCASGLQAVAMAADRIRVGEADVMIAAGVESMSMVPMMGNKPSMSPAIFARDENVGIAYG---MGLTAEKV 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 158 AEQFDISRADQDAFAQNSQEKAVAASQAGIFKEEIVAI-----------GDVGV-------DETPRPSSSLEKLATLRTA 219
Cdd:PRK09052 162 AEQWKVSREDQDAFALESHQKAIAAQQAGEFKDEITPYeiterfpdlatGEVDVktrtvdlDEGPRADTSLEGLAKLKPV 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 220 FKENGTVTAGNSSPVNDGASAVILATKDYAEKHEIPYLAELVDSTEVGIDPAIMGVSPIEAIKKLINRSELELSDIDLFE 299
Cdd:PRK09052 242 FANKGSVTAGNSSQTSDGAGAVILVSEKALKQFNLTPLARFVSFAVAGVPPEIMGIGPIEAIPAALKQAGLKQDDLDWIE 321
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2676378839 300 INEAFAASSLAVNRELGLNESQVNIYGGAIALGHAIGSSGSKILTTLSYALKREQKRYGIASLCI 364
Cdd:PRK09052 322 LNEAFAAQSLAVIRDLGLDPSKVNPLGGAIALGHPLGATGAIRTATVVHGLRRTNLKYGMVTMCV 386
|
|
| PRK06205 |
PRK06205 |
acetyl-CoA C-acetyltransferase; |
1-364 |
4.88e-106 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 235741 [Multi-domain] Cd Length: 404 Bit Score: 317.70 E-value: 4.88e-106
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 1 MKEIVIIDALRTPVGRYDGALAEYSAAELGTHVVSNLLSKHENIKSDVEQVIFGNVLQAGNGQNIARQIAIHSGLPNTVP 80
Cdd:PRK06205 1 MRDAVICEPVRTPVGRFGGAFKDVPAEELAATVIRALVERTGIDPARIDDVIFGQGYPNGEAPAIGRVAALDAGLPVTVP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 81 ASTINEVCGSGMKAVILAKQLLQLGEAEVVIAGGTESMSNAPIIKN--RKTQEETLSMLNDGLVDA---FSGISMGIIG- 154
Cdd:PRK06205 81 GMQLDRRCGSGLQAVITAAMQVQTGAADVVIAGGAESMSNVEFYTTdmRWGVRGGGVQLHDRLARGretAGGRRFPVPGg 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 155 -----ETIAEQFDISRADQDAFAQNSQEKAVAASQAGIFKEEIVAI------GD---VGVDETPRPSSSLEKLATLRT-- 218
Cdd:PRK06205 161 mietaENLRREYGISREEQDALAVRSHQRAVAAQEAGRFDDEIVPVtvpqrkGDptvVDRDEHPRADTTLESLAKLRPim 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 219 -AFKENGTVTAGNSSPVNDGASAVILATKDYAEKHEIPYLAELVDSTEVGIDPAIMGVSPIEAIKKLINRSELELSDIDL 297
Cdd:PRK06205 241 gKQDPEATVTAGNASGQNDAAAACLVTTEDKAEELGLRPLARLVSWAVAGVEPSRMGIGPVPATEKALARAGLTLDDIDL 320
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 298 FEINEAFAASSLAVNRELGLNES---QVNIYGGAIALGHAIGSSGSKILTTLSYALKREQKRYGIASLCI 364
Cdd:PRK06205 321 IELNEAFAAQVLAVLKEWGFGADdeeRLNVNGSGISLGHPVGATGGRILATLLRELQRRQARYGLETMCI 390
|
|
| PRK07661 |
PRK07661 |
acetyl-CoA C-acetyltransferase; |
1-364 |
2.89e-101 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 181072 [Multi-domain] Cd Length: 391 Bit Score: 305.14 E-value: 2.89e-101
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 1 MKEIVIIDALRTPVGRYD-GALAEYSAAELGTHVVSNLLSKHENIKSDVEQVIFGNVL-QAGNGQNIARQIAIHSGLPNT 78
Cdd:PRK07661 1 MREAVIVAGARTPVGKAKkGSLKTVRPDDLGALVVKETLKRAGNYEGPIDDLIIGCAMpEAEQGLNMARNIGALAGLPYT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 79 VPASTINEVCGSGMKAVILAKQLLQLGEAEVVIAGGTESMSNAPIIKNrktqeetLSMLNDGLVDAFSG--ISMGIIGET 156
Cdd:PRK07661 81 VPAITINRYCSSGLQSIAYGAERIMLGHSEAVIAGGAESMSLVPMMGH-------VVRPNPRLVEAAPEyyMGMGHTAEQ 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 157 IAEQFDISRADQDAFAQNSQEKAVAASQAGIFKEEIV-------AIGD----------VGVDETPRPSSSLEKLATLRTA 219
Cdd:PRK07661 154 VAVKYGISREDQDAFAVRSHQRAAKALAEGKFADEIVpvdvtlrTVGEnnklqeetitFSQDEGVRADTTLEILGKLRPA 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 220 FKENGTVTAGNSSPVNDGASAVILATKDYAEKHEIPYLAELVDSTEVGIDPAIMGVSPIEAIKKLINRSELELSDIDLFE 299
Cdd:PRK07661 234 FNVKGSVTAGNSSQMSDGAAAVLLMDREKAESDGLKPLAKFRSFAVAGVPPEVMGIGPIAAIPKALKLAGLELSDIGLFE 313
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2676378839 300 INEAFAASSLAVNRELGLNESQVNIYGGAIALGHAIGSSGSKILTTLSYALKREQKRYGIASLCI 364
Cdd:PRK07661 314 LNEAFASQSIQVIRELGLDEEKVNVNGGAIALGHPLGCTGAKLTLSLIHEMKRRNEQFGIVTMCI 378
|
|
| fadA |
PRK08947 |
3-ketoacyl-CoA thiolase; Reviewed |
1-364 |
8.95e-101 |
|
3-ketoacyl-CoA thiolase; Reviewed
Pssm-ID: 181592 [Multi-domain] Cd Length: 387 Bit Score: 303.43 E-value: 8.95e-101
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 1 MKEIVIIDALRTPVGRYDGALAEYSAAE-LGTHVVSNLLSKHENIK-SDVEQVIFGNVLQAG-NGQNIARQIAIHSGLPN 77
Cdd:PRK08947 1 MEDVVIVDAIRTPMGRSKGGAFRNVRAEdLSAHLMRSLLARNPALDpAEIDDIIWGCVQQTLeQGFNIARNAALLAGIPH 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 78 TVPASTINEVCGSGMKAVILAKQLLQLGEAEVVIAGGTESMSNAPiiknrktqeetlsmLNDGlVDAFSGIS-------- 149
Cdd:PRK08947 81 SVPAVTVNRLCGSSMQALHDAARAIMTGDGDVFLIGGVEHMGHVP--------------MNHG-VDFHPGLSknvakaag 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 150 -MGIIGETIAEQFDISRADQDAFAQNSQEKAVAASQAGIFKEEIVAIGD---------VGVDETPRPSSSLEKLATLRTA 219
Cdd:PRK08947 146 mMGLTAEMLGKMHGISREQQDAFAARSHQRAWAATQEGRFKNEIIPTEGhdadgvlklFDYDEVIRPETTVEALAALRPA 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 220 FK-ENGTVTAGNSSPVNDGASAVILATKDYAEKHEIPYLAELVDSTEVGIDPAIMGVSPIEAIKKLINRSELELSDIDLF 298
Cdd:PRK08947 226 FDpVNGTVTAGTSSALSDGASAMLVMSESRAKELGLKPRARIRSMAVAGCDPSIMGYGPVPATQKALKRAGLSISDIDVF 305
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2676378839 299 EINEAFAASSLAVNRELGLNES---QVNIYGGAIALGHAIGSSGSKILTTLSYALKREQKRYGIASLCI 364
Cdd:PRK08947 306 ELNEAFAAQSLPCLKDLGLLDKmdeKVNLNGGAIALGHPLGCSGARISTTLLNLMERKDAQFGLATMCI 374
|
|
| PRK08131 |
PRK08131 |
3-oxoadipyl-CoA thiolase; |
1-364 |
6.38e-96 |
|
3-oxoadipyl-CoA thiolase;
Pssm-ID: 181242 [Multi-domain] Cd Length: 401 Bit Score: 291.68 E-value: 6.38e-96
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 1 MKEIVIIDALRTPVGRYDGALAEYSAAELGTHVVSNLLSKHENIKSDVEQVIFGNVLQAG-NGQNIARQIAIHSGLPNTV 79
Cdd:PRK08131 1 MLDAYIYDGLRSPFGRHAGALASVRPDDLAATVIRRLLEKSGFPGDDIEDVILGCTNQAGeDSRNVARNALLLAGLPVTV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 80 PASTINEVCGSGMKAVILAKQLLQLGEAEVVIAGGTESMSNAPII--KNRKTQEETLSML---------NDGLVDAFSGI 148
Cdd:PRK08131 81 PGQTVNRLCASGLAAVIDAARAITCGEGDLYLAGGVESMSRAPFVmgKAESAFSRDAKVFdttigarfpNPKIVAQYGND 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 149 SMGIIGETIAEQFDISRADQDAFAQNSQEKAVAASQAGIFKEEIVAIG----------DVGVDETPRPSSSLEKLATLRT 218
Cdd:PRK08131 161 SMPETGDNVAAEFGISREDADRFAAQSQAKYQAAKEEGFFADEITPIEvpqgrklppkLVAEDEHPRPSSTVEALTKLKP 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 219 AFkENGTVTAGNSSPVNDGASAVILATKDYAEKHEIPYLAELVDSTEVGIDPAIMGVSPIEAIKKLINRSELELSDIDLF 298
Cdd:PRK08131 241 LF-EGGVVTAGNASGINDGAAALLIGSRAAGEKYGLKPMARILSSAAAGVEPRIMGIGPVEAIKKALARAGLTLDDMDII 319
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2676378839 299 EINEAFAASSLAVNRELGL--NESQVNIYGGAIALGHAIGSSGSKILTTLSYALKREQKRYGIASLCI 364
Cdd:PRK08131 320 EINEAFASQVLGCLKGLGVdfDDPRVNPNGGAIAVGHPLGASGARLALTAARELQRRGKRYAVVSLCI 387
|
|
| PRK07801 |
PRK07801 |
acetyl-CoA C-acetyltransferase; |
1-363 |
8.88e-96 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 181123 [Multi-domain] Cd Length: 382 Bit Score: 290.46 E-value: 8.88e-96
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 1 MKEIVIIDALRTPVGRYDGALAEYSAAELGTHVVSNLLSKHENIKSDVEQVIFGNVLQAGnGQ--NIARQIAIHSGLPNT 78
Cdd:PRK07801 1 MAEAYIVDAVRTPVGKRKGGLAGVHPADLGAHVLKGLVDRTGIDPAAVDDVIFGCVDTIG-PQagNIARTSWLAAGLPEE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 79 VPASTINEVCGSGMKAVILAKQLLQLGEAEVVIAGGTESMSNAPIIKNRKTQEETlsmlndGLVDAFSG----------- 147
Cdd:PRK07801 80 VPGVTVDRQCGSSQQAIHFAAQAVMSGTQDLVVAGGVQNMSQIPISSAMTAGEQL------GFTSPFAEskgwlhrygdq 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 148 -ISMGIIGETIAEQFDISRADQDAFAQNSQEKAVAASQAGIFKEEIVAIGDVGVDETPRpSSSLEKLATLRTaFKENGTV 226
Cdd:PRK07801 154 eVSQFRGAELIAEKWGISREEMERFALESHRRAFAAIRAGRFDNEIVPVGGVTVDEGPR-ETSLEKMAGLKP-LVEGGRL 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 227 TAGNSSPVNDGASAVILATKDYAEKHEIPYLAELVDSTEVGIDPAIMGVSPIEAIKKLINRSELELSDIDLFEINEAFAA 306
Cdd:PRK07801 232 TAAVASQISDGASAVLLASERAVKRHGLTPRARIHHLSVRGDDPVFMLTAPIPATRYALEKTGLSIDDIDVVEINEAFAP 311
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*..
gi 2676378839 307 SSLAVNRELGLNESQVNIYGGAIALGHAIGSSGSKILTTLSYALKREQKRYGIASLC 363
Cdd:PRK07801 312 VVLAWLKETGADPAKVNPNGGAIALGHPLGATGAKLMTTLLHELERTGGRYGLQTMC 368
|
|
| PRK08170 |
PRK08170 |
acetyl-CoA C-acetyltransferase; |
1-364 |
7.13e-95 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 181265 [Multi-domain] Cd Length: 426 Bit Score: 289.61 E-value: 7.13e-95
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 1 MKEIVIIDALRTPVGRYDGALAEYSAAELGTHVVSNLLSKHENIKSDVEQVIFGNVLQAGNGQNIARQIAIHSGLPNTVP 80
Cdd:PRK08170 2 ARPVYIVDGARTPFLKARGGPGPFSASDLAVAAGRALLNRQPFAPDDLDEVILGCAMPSPDEANIARVVALRLGCGEKVP 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 81 ASTINEVCGSGMKAVILAKQLLQLGEAEVVIAGGTESMSNAPIIKNR------------KTQEETLSMLND--------- 139
Cdd:PRK08170 82 AWTVQRNCASGMQALDSAAANIALGRADLVLAGGVEAMSHAPLLFSEkmvrwlagwyaaKSIGQKLAALGKlrpsylapv 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 140 -----GLVDAFSGISMGIIGETIAEQFDISRADQDAFAQNSQEKAVAASQAGIFKEEIVAIGDVGV----DETPRPSSSL 210
Cdd:PRK08170 162 igllrGLTDPVVGLNMGQTAEVLAHRFGITREQMDAYAARSHQRLAAAQAEGRLKEVVPLFDRDGKfydhDDGVRPDSSM 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 211 EKLATLRTAF-KENGTVTAGNSSPVNDGASAVILATKDYAEKHEIPYLAELVDSTEVGIDPAIMGVSPIEAIKKLINRSE 289
Cdd:PRK08170 242 EKLAKLKPFFdRPYGRVTAGNSSQITDGACWLLLASEEAVKKYGLPPLGRIVDSQWAALDPSQMGLGPVHAATPLLQRHG 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 290 LELSDIDLFEINEAFAASSLAVNR----------ELGL-------NESQVNIYGGAIALGHAIGSSGSKILTTLSYALKR 352
Cdd:PRK08170 322 LTLEDLDLWEINEAFAAQVLACLAawadeeycreQLGLdgalgelDRERLNVDGGAIALGHPVGASGARIVLHLLHALKR 401
|
410
....*....|..
gi 2676378839 353 EQKRYGIASLCI 364
Cdd:PRK08170 402 RGTKRGIAAICI 413
|
|
| PLN02287 |
PLN02287 |
3-ketoacyl-CoA thiolase |
3-364 |
5.99e-93 |
|
3-ketoacyl-CoA thiolase
Pssm-ID: 215161 [Multi-domain] Cd Length: 452 Bit Score: 285.89 E-value: 5.99e-93
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 3 EIVIIDALRTPVGRYD-GALAEYSAAELGTHVVSNLLSKHENIKSDVEQVIFGNVLQAGNGQ-NIARQIAIHSGLPNTVP 80
Cdd:PLN02287 47 DVVIVAAYRTPICKAKrGGFKDTYPDDLLAPVLKAVVEKTGLNPSEVGDIVVGTVLAPGSQRaNECRMAAFYAGFPETVP 126
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 81 ASTINEVCGSGMKAVILAKQLLQLGEAEVVIAGGTESMSNAPIIKNRKT--QEETLSMLNDGLvdafsgISMGIIGETIA 158
Cdd:PLN02287 127 VRTVNRQCSSGLQAVADVAAAIKAGFYDIGIGAGVESMTTNPMAWEGGVnpRVESFSQAQDCL------LPMGITSENVA 200
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 159 EQFDISRADQDAFAQNSQEKAVAASQAGIFKEEIVAIGD--------------VGVDETPRPSSSLEKLATLRTAFKENG 224
Cdd:PLN02287 201 ERFGVTREEQDQAAVESHRKAAAATASGKFKDEIVPVHTkivdpktgeekpivISVDDGIRPNTTLADLAKLKPVFKKNG 280
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 225 TVTAGNSSPVNDGASAVILATKDYAEKHEIPYLAELVDSTEVGIDPAIMGVSPIEAIKKLINRSELELSDIDLFEINEAF 304
Cdd:PLN02287 281 TTTAGNSSQVSDGAGAVLLMKRSVAMQKGLPILGVFRSFAAVGVDPAVMGIGPAVAIPAAVKAAGLELDDIDLFEINEAF 360
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2676378839 305 AASSLAVNRELGLNESQVNIYGGAIALGHAIGSSGSKILTTLSYALKREQK--RYGIASLCI 364
Cdd:PLN02287 361 ASQFVYCCKKLGLDPEKVNVNGGAIALGHPLGATGARCVATLLHEMKRRGKdcRFGVVSMCI 422
|
|
| PRK06954 |
PRK06954 |
acetyl-CoA C-acetyltransferase; |
1-364 |
5.04e-92 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 180775 [Multi-domain] Cd Length: 397 Bit Score: 281.40 E-value: 5.04e-92
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 1 MKEIVIIDALRTPVGRYDGALAEYSAAELGTHVVSNLLSKHENIKSDVEQVIFGNVLQAGNGQNIARQIAIHSGLPNTVP 80
Cdd:PRK06954 6 QDPIVIASAARTPMAAFQGEFASLTAPQLGAAAIAAAVERAGLKPEQIDEVVMGCVLPAGQGQAPARQAALGAGLPLSVG 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 81 ASTINEVCGSGMKAVILAKQLLQLGEAEVVIAGGTESMSNAPII------KNRKTQEETLS-MLNDGLVDAFS-GISMGI 152
Cdd:PRK06954 86 CTTVNKMCGSGMRAAMFAHDMLVAGSVDVIVAGGMESMTNAPYLlpkargGMRMGHGQVLDhMFLDGLEDAYDkGRLMGT 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 153 IGETIAEQFDISRADQDAFAQNSQEKAVAASQAGIFKEEIVAI------GDVGV--DETPRpSSSLEKLATLRTAFKENG 224
Cdd:PRK06954 166 FAEECAGEYGFTREAQDAFAIESLARAKRANEDGSFAWEIAPVtvagkkGDTVIdrDEQPF-KANPEKIPTLKPAFSKTG 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 225 TVTAGNSSPVNDGASAVILATKDYAEKHEIPYLAELVDSTEVGIDPAIMGVSPIEAIKKLINRSELELSDIDLFEINEAF 304
Cdd:PRK06954 245 TVTAANSSSISDGAAALVMMRASTAKRLGLAPLARVVGHSTFAQAPSKFTTAPVGAIRKLFEKNGWRAAEVDLFEINEAF 324
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 305 AASSLAVNRELGLNESQVNIYGGAIALGHAIGSSGSKILTTLSYALKREQKRYGIASLCI 364
Cdd:PRK06954 325 AVVTMAAMKEHGLPHEKVNVNGGACALGHPIGASGARILVTLIGALRARGGKRGVASLCI 384
|
|
| Thiolase_N |
pfam00108 |
Thiolase, N-terminal domain; Thiolase is reported to be structurally related to beta-ketoacyl ... |
4-247 |
4.32e-91 |
|
Thiolase, N-terminal domain; Thiolase is reported to be structurally related to beta-ketoacyl synthase (pfam00109), and also chalcone synthase.
Pssm-ID: 459676 [Multi-domain] Cd Length: 260 Bit Score: 274.18 E-value: 4.32e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 4 IVIIDALRTPVGRYDGALAEYSAAELGTHVVSNLLSKHENIKSDVEQVIFGNVLQAGNGQNIARQIAIHSGLPNTVPAST 83
Cdd:pfam00108 1 VVIVSAARTPFGSFGGSLKDVSAVELGAEAIKAALERAGVDPEDVDEVIVGNVLQAGEGQNPARQAALKAGIPDSAPAVT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 84 INEVCGSGMKAVILAKQLLQLGEAEVVIAGGTESMSNAPIIKNRKTQEETL--------SMLNDGLVDAFSGISMGIIGE 155
Cdd:pfam00108 81 INKVCGSGLKAVYLAAQSIASGDADVVLAGGVESMSHAPYALPTDARSGLKhgdekkhdLLIPDGLTDAFNGYHMGLTAE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 156 TIAEQFDISRADQDAFAQNSQEKAVAASQAGIFKEEIVAIGDVG--------VDETPRPSSSLEKLATLRTAFKENGTVT 227
Cdd:pfam00108 161 NVAKKYGISREEQDAFAVKSHQKAAAAPKAGKFKDEIVPVTVKGrkgkptvdKDEGIRPPTTAEPLAKLKPAFDKEGTVT 240
|
250 260
....*....|....*....|
gi 2676378839 228 AGNSSPVNDGASAVILATKD 247
Cdd:pfam00108 241 AGNASPINDGAAAVLLMSES 260
|
|
| PRK06366 |
PRK06366 |
acetyl-CoA C-acetyltransferase; |
1-363 |
1.38e-90 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 102340 [Multi-domain] Cd Length: 388 Bit Score: 277.66 E-value: 1.38e-90
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 1 MKEIVIIDALRTPVGRYDGALAEYSAAELGTHVVSNLLSKHENIKSDVEQVIFGNVLQAGNGQNIARQIAIHSGLPNTVP 80
Cdd:PRK06366 1 MKDVYIVSAKRTAIGKFGRSFSKIKAPQLGGAAIKAVIDDAKLDPALVQEVIMGNVIQAGVGQNPAGQAAYHAGLPFGVT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 81 ASTINEVCGSGMKAVILAKQLLQLGEAEVVIAGGTESMSNAPII--------------KNRKTQEetlSMLNDGLVDAFS 146
Cdd:PRK06366 81 KYTVNVVCASGMLAVESAAREIMLGERDLVIAGGMENMSNAPFLlpsdlrwgpkhllhKNYKIDD---AMLVDGLIDAFY 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 147 GISMGIIGETIAEQFDISRADQDAFAQNSQEKAVAASQAGIFKEEIVAIGDVGVDETPRpSSSLEKLATLRTAFKENGTV 226
Cdd:PRK06366 158 FEHMGVSAERTARKYGITREMADEYSVQSYERAIRATESGEFRNEIVPFNDLDRDEGIR-KTTMEDLAKLPPAFDKNGIL 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 227 TAGNSSPVNDGASAVILATKDYAEKHEIPYLAELVDSTEVGIDPAIMGVSPIEAIKKLINRSELELSDIDLFEINEAFAA 306
Cdd:PRK06366 237 TAGNSAQLSDGGSALVMASEKAINEYGLKPIARITGYESASLDPLDFVEAPIPATRKLLEKQNKSIDYYDLVEHNEAFSI 316
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*..
gi 2676378839 307 SSLAVNRELGLNESQVNIYGGAIALGHAIGSSGSKILTTLSYALKREQKRYGIASLC 363
Cdd:PRK06366 317 ASIIVRDQLKIDNERFNVNGGAVAIGHPIGNSGSRIIVTLINALKTRHMKTGLATLC 373
|
|
| PRK07851 |
PRK07851 |
acetyl-CoA C-acetyltransferase; |
1-364 |
2.16e-87 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 181146 [Multi-domain] Cd Length: 406 Bit Score: 269.95 E-value: 2.16e-87
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 1 MKEIVIIDALRTPVGR-YDGALAEYSAAELGTHVVSNLLSKHENIK-SDVEQVIFGNVLQAG-NGQNIARQIAIHSGLPn 77
Cdd:PRK07851 1 MPEAVIVSTARSPIGRaFKGSLKDMRPDDLAAQMVRAALDKVPALDpTDIDDLMLGCGLPGGeQGFNMARVVAVLLGYD- 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 78 TVPASTINEVCGSGMKAVILAKQLLQLGEAEVVIAGGTESMS--------NAPIIKN---RKTQEETLSML--------- 137
Cdd:PRK07851 80 FLPGTTVNRYCSSSLQTTRMAFHAIKAGEGDVFISAGVETVSrfakgnsdSLPDTKNplfAEAQARTAARAeggaeawhd 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 138 --NDGLV-DAFsgISMGIIGETIAEQFDISRADQDAFAQNSQEKAVAASQAGIFKEEI--VAIGD---VGVDETPRPSSS 209
Cdd:PRK07851 160 prEDGLLpDVY--IAMGQTAENVAQLTGISREEQDEWGVRSQNRAEEAIANGFFEREItpVTLPDgtvVSTDDGPRAGTT 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 210 LEKLATLRTAFKENGTVTAGNSSPVNDGASAVILATKDYAEKHEIPYLAELVdSTEV-GIDPAIMGVSPIEAIKKLINRS 288
Cdd:PRK07851 238 YEKVSQLKPVFRPDGTVTAGNACPLNDGAAAVVIMSDTKARELGLTPLARIV-STGVsGLSPEIMGLGPVEASKQALARA 316
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2676378839 289 ELELSDIDLFEINEAFAASSLAVNRELGLNESQVNIYGGAIALGHAIGSSGSKILTTLSYALKREQKRYGIASLCI 364
Cdd:PRK07851 317 GMSIDDIDLVEINEAFAAQVLPSARELGIDEDKLNVSGGAIALGHPFGMTGARITTTLLNNLQTHDKTFGLETMCV 392
|
|
| PRK06445 |
PRK06445 |
acetyl-CoA C-acetyltransferase; |
1-364 |
1.82e-86 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 180563 [Multi-domain] Cd Length: 394 Bit Score: 267.36 E-value: 1.82e-86
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 1 MKEIVIIDALRTPVGRYDGALAE------YSAAELGTHVVSNLLSKHENIKSDVEQVIFGNVLQAG-NGQNIARQIAIHS 73
Cdd:PRK06445 1 LEDVYLVDFARTAFSRFRPKDPQkdvfnnIRPEELAAMLINRLIEKTGIKPEEIDDIITGCALQVGeNWLYGGRHPIFLA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 74 GLPNTVPASTINEVCGSGMKAVILAKQLLQLGEAEVVIAGGTESMSNAPIIKNRKTQEETLSMLNDGLV--DAFSGISMG 151
Cdd:PRK06445 81 RLPYNIPAMAVDRQCASSLTTVSIGAMEIATGMADIVIAGGVEHMTRTPMGDNPHIEPNPKLLTDPKYIeyDLTTGYVMG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 152 IIGETIAEQFDISRADQDAFAQNSQEKAVAASQAGIFKEEIVAI-----GD---VGVDETPRPSSSLEKLATLRTAFKEN 223
Cdd:PRK06445 161 LTAEKLAEEAGIKREEMDRWSLRSHQLAAKAIQEGYFKDEILPIeveveGKkkvVDVDQSVRPDTSLEKLAKLPPAFKPD 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 224 GTVTAGNSSPVNDGASAVILATKDYAEKHEIPYLAELVDSTEVGIDPAIMGVSPIEAIKKLINRSELELSDIDLFEINEA 303
Cdd:PRK06445 241 GVITAGNSSPLNSGASYVLLMSKKAVKKYGLKPMAKIRSFGFAGVPPAIMGKGPVPASKKALEKAGLSVKDIDLWEINEA 320
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2676378839 304 FAASSLAVNRELGLNESQVNIYGGAIALGHAIGSSGSKILTTLSYALKREQKRYGIASLCI 364
Cdd:PRK06445 321 FAVVVLYAIKELGLDPETVNIKGGAIAIGHPLGATGARIVGTLARQLQIKGKDYGVATLCV 381
|
|
| PRK08242 |
PRK08242 |
acetyl-CoA C-acetyltransferase; |
1-364 |
4.78e-86 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 236197 [Multi-domain] Cd Length: 402 Bit Score: 266.36 E-value: 4.78e-86
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 1 MKEIVIIDALRTPVGR--YDGALAEYSAAELGTHVVSNLLSKHENIKSDVEQVIFGNVLQAGN-GQNIARQIAIHSGLPN 77
Cdd:PRK08242 1 MTEAYIYDAVRTPRGKgkKDGSLHEVKPVRLAAGLLEALRDRNGLDTAAVDDVVLGCVTPVGDqGADIARTAVLAAGLPE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 78 TVPASTINEVCGSGMKAVILAKQLLQLGEAEVVIAGGTESMSNAPiiknrktqeetlsMLNDG---LVDAFSGIS----- 149
Cdd:PRK08242 81 TVPGVQINRFCASGLEAVNLAAAKVRSGWDDLVIAGGVESMSRVP-------------MGSDGgawAMDPSTNFPtyfvp 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 150 MGIIGETIAEQFDISRADQDAFAQNSQEKAVAASQAGIFKEEIVAIGDV-GV-----DETPRPSSSLEKLATLRTAFKEN 223
Cdd:PRK08242 148 QGISADLIATKYGFSREDVDAYAVESQQRAAAAWAEGYFAKSVVPVKDQnGLtildhDEHMRPGTTMESLAKLKPSFAMM 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 224 GTV---------------------TAGNSSPVNDGASAVILATKDYAEKHEIPYLAELVDSTEVGIDPAIMGVSPIEAIK 282
Cdd:PRK08242 228 GEMggfdavalqkypeverinhvhHAGNSSGIVDGAAAVLIGSEEAGKALGLKPRARIVATATIGSDPTIMLTGPVPATR 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 283 KLINRSELELSDIDLFEINEAFAASSLAVNRELGLNESQVNIYGGAIALGHAIGSSGSKILTTLSYALKREQKRYGIASL 362
Cdd:PRK08242 308 KALAKAGLTVDDIDLFELNEAFASVVLRFMQALDIPHDKVNVNGGAIAMGHPLGATGAMILGTVLDELERRGKRTALITL 387
|
..
gi 2676378839 363 CI 364
Cdd:PRK08242 388 CV 389
|
|
| PRK06690 |
PRK06690 |
acetyl-CoA C-acyltransferase; |
5-362 |
4.52e-83 |
|
acetyl-CoA C-acyltransferase;
Pssm-ID: 180659 [Multi-domain] Cd Length: 361 Bit Score: 257.39 E-value: 4.52e-83
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 5 VIIDALRTPVGRYDGALAEYSAAELGTHVVSnLLSKheNIKSDVEQVIFGNVLqaGNGQNIARQIAIHSGLPNTVPASTI 84
Cdd:PRK06690 4 VIVEAKRTPIGKKNGMLKDYEVQQLAAPLLT-FLSK--GMEREIDDVILGNVV--GPGGNVARLSALEAGLGLHIPGVTI 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 85 NEVCGSGMKAVILAKQLLQLGEAEVVIAGGTESMSNAPIIKNRKTQEETLSmlndglvdafsGISMGIIGETIAEQFDIS 164
Cdd:PRK06690 79 DRQCGAGLEAIRTACHFIQGGAGKCYIAGGVESTSTSPFQNRARFSPETIG-----------DPDMGVAAEYVAERYNIT 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 165 RADQDAFAQNSQEKAVAASQAGIFKEEIVAIGDVgVDETPRPSSSLEKL-ATLRTAFKENGTVTAGNSSPVNDGASAVIL 243
Cdd:PRK06690 148 REMQDEYACLSYKRTLQALEKGYIHEEILSFNGL-LDESIKKEMNYERIiKRTKPAFLHNGTVTAGNSCGVNDGACAVLV 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 244 ATKDYAEKHEIPYLAELVDSTEVGIDPAIMGVSPIEAIKKLINRSELELSDIDLFEINEAFAASSLAVNRELGLNESQVN 323
Cdd:PRK06690 227 MEEGQARKLGYKPVLRFVRSAVVGVDPNLPGTGPIFAVNKLLNEMNMKVEDIDYFEINEAFASKVVACAKELQIPYEKLN 306
|
330 340 350
....*....|....*....|....*....|....*....
gi 2676378839 324 IYGGAIALGHAIGSSGSKILTTLSYALKREQKRYGIASL 362
Cdd:PRK06690 307 VNGGAIALGHPYGASGAMLVTRLFYQAKREDMKYGIATL 345
|
|
| PRK06504 |
PRK06504 |
acetyl-CoA C-acetyltransferase; |
1-363 |
1.48e-81 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 180595 [Multi-domain] Cd Length: 390 Bit Score: 254.27 E-value: 1.48e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 1 MKEIVIIDALRTPVGRYDGALAEYSAAELGTHVVSNLLSKHENIKSDVEQVIFGNVLQAG-NGQNIARQIAIHSGLPNTV 79
Cdd:PRK06504 1 MAEAYIVAAARTAGGRKGGRLAGWHPADLAAQVLDALVDRSGADPALIEDVIMGCVSQVGeQATNVARNAVLASKLPESV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 80 PASTINEVCGSGMKAVILAKQLLQLGEAEVVIAGGTESMSNAPIIKNrktqeETLSMLN-------DGLVDAFSGIS--- 149
Cdd:PRK06504 81 PGTSIDRQCGSSQQALHFAAQAVMSGTMDIVIAAGVESMTRVPMGSP-----STLPAKNglghyksPGMEERYPGIQfsq 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 150 -MGiiGETIAEQFDISRADQDAFAQNSQEKAVAASQAGIFKEEIVAI------GDVG---VDETPRPSSSLEKLATLRTa 219
Cdd:PRK06504 156 fTG--AEMMAKKYGLSKDQLDEFALQSHQRAIAATQAGKFKAEIVPLeitradGSGEmhtVDEGIRFDATLEGIAGVKL- 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 220 FKENGTVTAGNSSPVNDGASAVILATKDYAEKHEIPYLAELVDSTEVGIDPAIMGVSPIEAIKKLINRSELELSDIDLFE 299
Cdd:PRK06504 233 IAEGGRLTAATASQICDGASGVMVVNERGLKALGVKPLARIHHMTVIGGDPVIMLEAPLPATERALKKAGMKIDDIDLYE 312
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2676378839 300 INEAFAASSLAVNRELGLNESQVNIYGGAIALGHAIGSSGSKILTTLSYALKREQKRYGIASLC 363
Cdd:PRK06504 313 VNEAFASVPLAWLKATGADPERLNVNGGAIALGHPLGASGTKLMTTLVHALKQRGKRYGLQTMC 376
|
|
| PRK07850 |
PRK07850 |
steroid 3-ketoacyl-CoA thiolase; |
1-363 |
1.59e-76 |
|
steroid 3-ketoacyl-CoA thiolase;
Pssm-ID: 181145 [Multi-domain] Cd Length: 387 Bit Score: 241.55 E-value: 1.59e-76
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 1 MKEIVIIDALRTPVGRYDGALAEYSAAELGTHVVSNLLSKHENIKSDVEQVIFGNVLQAG-NGQNIARQIAIHSGLPNTV 79
Cdd:PRK07850 1 MGNPVIVEAVRTPIGKRNGWLSGLHAAELLGAVQRAVLDRAGIDPGDVEQVIGGCVTQAGeQSNNITRTAWLHAGLPYHV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 80 PASTINEVCGSGMKAVILAKQLLQLGEAEVVIAGGTESMSNAPIIKN-------RKTQEETLSMlndglVDAFSGismgi 152
Cdd:PRK07850 81 GATTIDCQCGSAQQANHLVAGLIAAGAIDVGIACGVEAMSRVPLGANagpgrglPRPDSWDIDM-----PNQFEA----- 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 153 iGETIAEQFDISRADQDAFAQNSQEKAVAASQAGIFKEEIVAIGDVGVDETPRPS--------------SSLEKLATLRT 218
Cdd:PRK07850 151 -AERIAKRRGITREDVDAFGLRSQRRAAQAWAEGRFDREISPVQAPVLDEEGQPTgetrlvtrdqglrdTTMEGLAGLKP 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 219 AFkENGTVTAGNSSPVNDGASAVILATKDYAEKHEIPYLAELVDSTEVGIDPAIMGVSPIEAIKKLINRSELELSDIDLF 298
Cdd:PRK07850 230 VL-EGGIHTAGTSSQISDGAAAVLWMDEDRARALGLRPRARIVAQALVGAEPYYHLDGPVQATAKVLEKAGMKIGDIDLV 308
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2676378839 299 EINEAFAASSLAVNRELGLNESQVNIYGGAIALGHAIGSSGSKILTTLSYALKREQKRYGIASLC 363
Cdd:PRK07850 309 EINEAFASVVLSWAQVHEPDMDKVNVNGGAIALGHPVGSTGARLITTALHELERTDKSTALITMC 373
|
|
| PRK07108 |
PRK07108 |
acetyl-CoA C-acyltransferase; |
1-364 |
4.99e-73 |
|
acetyl-CoA C-acyltransferase;
Pssm-ID: 180843 [Multi-domain] Cd Length: 392 Bit Score: 232.35 E-value: 4.99e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 1 MKEIVIIDALRTPVGR-YDGALAEYSAAELGTHVVSNLLSKHENIKSDVEQVIFGNVLQAG-NGQNIARQIAIHSGLPNT 78
Cdd:PRK07108 1 MTEAVIVSTARTPLAKsWRGAFNMTHGATLGGHVVQHAVERAKLDPAEVEDVIMGCANPEGaTGANIARQIALRAGLPVT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 79 VPASTINEVCGSGMKAVILAKQLLQLGEAEVVIAGGTESMSNApiiknrkTQEETLSMLNDG-LVDAFSGI--SMGIIGE 155
Cdd:PRK07108 81 VPGMTVNRFCSSGLQTIALAAQRVIAGEGDVFVAGGVESISCV-------QNEMNRHMLREGwLVEHKPEIywSMLQTAE 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 156 TIAEQFDISRADQDAFAQNSQEKAVAASQAGIFKEEIVAIG------------------DVGVDETPRPSSSLEKLATLR 217
Cdd:PRK07108 154 NVAKRYGISKERQDEYGVQSQQRAAAAQAAGRFDDEIVPITvtagvadkatgrlftkevTVSADEGIRPDTTLEGVSKIR 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 218 TAFkENGTVTAGNSSPVNDGASAVILATKDYAEKHEIPYLAELVDSTEVGIDPAIMGVSPIEAIKKLINRSELELSDIDL 297
Cdd:PRK07108 234 SAL-PGGVITAGNASQFSDGASACVVMNAKVAEREGLQPLGIFRGFAVAGCEPDEMGIGPVFAVPKLLKQAGLKVDDIDL 312
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2676378839 298 FEINEAFAASSLAVNRELGLNESQVNIYGGAIALGHAIGSSGSKILTTLSYALKREQKRYGIASLCI 364
Cdd:PRK07108 313 WELNEAFAVQVLYCRDTLGIPMDRLNVNGGAIAVGHPYGVSGARLTGHALIEGKRRGAKYVVVTMCI 379
|
|
| PRK06025 |
PRK06025 |
acetyl-CoA C-acetyltransferase; |
1-363 |
2.03e-68 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 235675 [Multi-domain] Cd Length: 417 Bit Score: 221.19 E-value: 2.03e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 1 MKEIVIIDALRTP-----VGRydGALAEYSAAELGTHVVSNLLSKHENIKSDVEQVIFGNVLQAG-NGQNIARQIAIHSG 74
Cdd:PRK06025 1 MAEAYIIDAVRTPrgigkVGK--GALAHLHPQHLAATVLKALAERNGLNTADVDDIIWSTSSQRGkQGGDLGRMAALDAG 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 75 LPNTVPASTINEVCGSGMKAVILAKQLLQLGEAEVVIAGGTESMS-NAPIIKNRKTQEETLSMLNDG---LVDAFSGISM 150
Cdd:PRK06025 79 YDIKASGVTLDRFCGGGITSVNLAAAQIMSGMEDLVIAGGTEMMSyTAAMAAEDMAAGKPPLGMGSGnlrLRALHPQSHQ 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 151 GIIGETIAEQFDISRADQDAFAQNSQEKAVAASQAGIFKEEIVAI----GDVGVD--ETPRPSSSLEKLATLRTAFK--- 221
Cdd:PRK06025 159 GVCGDAIATMEGITREALDALGLESQRRAARAIKEGRFDKSLVPVyrddGSVALDheEFPRPQTTAEGLAALKPAFTaia 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 222 -----ENGTVT------------------AGNSSPVNDGASAVILATKDYAEKHEIPYLAELVDSTEVGIDPAIMGVSPI 278
Cdd:PRK06025 239 dypldDKGTTYrglinqkypdleikhvhhAGNSSGVVDGAAALLLASKAYAEKHGLKPRARIVAMANMGDDPTLMLNAPV 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 279 EAIKKLINRSELELSDIDLFEINEAFAASSLAVNRELGLNESQVNIYGGAIALGHAIGSSGSKILTTLSYALKREQKRYG 358
Cdd:PRK06025 319 PAAKKVLAKAGLTKDDIDLWEINEAFAVVAEKFIRDLDLDRDKVNVNGGAIALGHPIGATGSILIGTVLDELERRGLKRG 398
|
....*
gi 2676378839 359 IASLC 363
Cdd:PRK06025 399 LVTMC 403
|
|
| nondecarbox_cond_enzymes |
cd00826 |
nondecarboxylating condensing enzymes; In general, thiolases catalyze the reversible thiolytic ... |
9-364 |
6.05e-67 |
|
nondecarboxylating condensing enzymes; In general, thiolases catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. There are 2 functional different classes: thiolase-I (3-ketoacyl-CoA thiolase) and thiolase-II (acetoacetyl-CoA thiolase). Thiolase-I can cleave longer fatty acid molecules and plays an important role in the beta-oxidative degradation of fatty acids. Thiolase-II has a high substrate specificity. Although it can cleave acetoacyl-CoA, its main function is the synthesis of acetoacyl-CoA from two molecules of acetyl-CoA, which gives it importance in several biosynthetic pathways.
Pssm-ID: 238422 [Multi-domain] Cd Length: 393 Bit Score: 216.98 E-value: 6.05e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 9 ALRTPVGRY---DGALAEYSAAELGTHVVSNLLSKHENIKSDVEQVIFGNVLQAGNGQNIARQIAIHSGLPNTVPASTIN 85
Cdd:cd00826 3 AAMTAFGKFggeNGADANDLAHEAGAKAIAAALEPAGVAAGAVEEACLGQVLGAGEGQNCAQQAAMHAGGLQEAPAIGMN 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 86 EVCGSGMKAVILAKQLLQLGEAEVVIAGGTESMSNAPiiKNRKTQEETLSMLNDGLvdafsgismgiigetiaeqfdiSR 165
Cdd:cd00826 83 NLCGSGLRALALAMQLIAGGDANCILAGGFEKMETSA--ENNAKEKHIDVLINKYG----------------------MR 138
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 166 ADQDAFAQNSQEKAVAASQAGIFKEEIVAI------GDVGVDETP----RPSSSLEKLATLRTAFKENGTVTAGNSSPVN 235
Cdd:cd00826 139 ACPDAFALAGQAGAEAAEKDGRFKDEFAKFgvkgrkGDIHSDADEyiqfGDEASLDEIAKLRPAFDKEDFLTAGNACGLN 218
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 236 DGASAVILATKDYAEKH-------EIPYLAELVDSTEVGIDPA----IMGVSPIEAIKKLINRSELELSDIDLFEINEAF 304
Cdd:cd00826 219 DGAAAAILMSEAEAQKHglqskarEIQALEMITDMASTFEDKKvikmVGGDGPIEAARKALEKAGLGIGDLDLIEAHDAF 298
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 305 AASSLAVNRELGL------------------NESQVNIYGGAIALGHAIGSSGSKILTTLSYALKREQK-----RYGIAS 361
Cdd:cd00826 299 AANACATNEALGLcpegqggalvdrgdntygGKSIINPNGGAIAIGHPIGASGAAICAELCFELKGEAGkrqgaGAGLAL 378
|
...
gi 2676378839 362 LCI 364
Cdd:cd00826 379 LCI 381
|
|
| fadI |
PRK08963 |
3-ketoacyl-CoA thiolase; Reviewed |
4-363 |
2.86e-64 |
|
3-ketoacyl-CoA thiolase; Reviewed
Pssm-ID: 181597 [Multi-domain] Cd Length: 428 Bit Score: 211.00 E-value: 2.86e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 4 IVIIDALRTPVGRYDGALAEYSAAELGTHVVSNLLSKHENIKSDVEQVIFGNVLQAGNGQNIARQIAIHSGLPNTVPAST 83
Cdd:PRK08963 7 IAIVSGLRTPFAKQATAFHGIPAVDLGKMVVGELLARSEIDPELIEQLVFGQVVQMPEAPNIAREIVLGTGMNVHTDAYS 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 84 INEVCGSGMKAVILAKQLLQLGEAEVVIAGGTESMSNAPIIKNRKTQEETLSM-----------------LNDGL----- 141
Cdd:PRK08963 87 VSRACATSFQAVANVAESIMAGTIDIGIAGGADSSSVLPIGVSKKLARALVDLnkartlgqrlklfsrlrLRDLLpvppa 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 142 VDAFS-GISMGIIGETIAEQFDISRADQDAFAQNSQEKAVAASQAGIFKEEIVAI------GDVGVDETPRPSSSLEKLA 214
Cdd:PRK08963 167 VAEYStGLRMGDTAEQMAKTYGISREEQDALAHRSHQLAAQAWAEGKLDDEVMTAhvppykQPLEEDNNIRGDSTLEDYA 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 215 TLRTAF-KENGTVTAGNSSPVNDGASAVILATKDYAEKHEIPYLAELVDSTEVGIDP---AIMGvsPIEAIKKLINRSEL 290
Cdd:PRK08963 247 KLRPAFdRKHGTVTAANSTPLTDGAAAVLLMSESRAKALGLTPLGYLRSYAFAAIDVwqdMLLG--PAYATPLALERAGL 324
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 291 ELSDIDLFEINEAFAASSLA----------VNRELGLNE-------SQVNIYGGAIALGHAIGSSGSKILTTLSYALKRE 353
Cdd:PRK08963 325 TLADLTLIDMHEAFAAQTLAnlqmfaserfAREKLGRSQaigevdmSKFNVLGGSIAYGHPFAATGARMITQTLHELRRR 404
|
410
....*....|
gi 2676378839 354 QKRYGIASLC 363
Cdd:PRK08963 405 GGGLGLTTAC 414
|
|
| PRK09268 |
PRK09268 |
acetyl-CoA C-acetyltransferase; |
1-363 |
7.16e-60 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 236440 [Multi-domain] Cd Length: 427 Bit Score: 199.36 E-value: 7.16e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 1 MKEIVIIDALRTPVGRYDGALAEYSAAELGTHVVSNLLSKHENIKSDVEQVIFGNVLQAGNGQNIARQIAIHSGLPNTVP 80
Cdd:PRK09268 6 VRRVAILGGNRIPFARSNGAYADASNQDMLTAALDGLVDRFGLQGERLGEVVAGAVLKHSRDFNLTRECVLGSALSPYTP 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 81 ASTINEVCGSGMKAVILAKQLLQLGEAEVVIAGGTESMSNAPIIKNR------------KTQEETLSMLNDG----LVDA 144
Cdd:PRK09268 86 AYDLQQACGTGLEAAILVANKIALGQIDSGIAGGVDTTSDAPIAVNEglrkillelnraKTTGDRLKALGKLrpkhLAPE 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 145 F-------SGISMGIIGETIAEQFDISRADQDAFAQNSQEKAVAASQAGIFKEEIVAIGDVGVDETPRPSSSLEKLATLR 217
Cdd:PRK09268 166 IprngeprTGLSMGEHAAITAKEWGISREAQDELAAASHQNLAAAYDRGFFDDLITPFLGLTRDNNLRPDSSLEKLAKLK 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 218 TAF--KENGTVTAGNSSPVNDGASAVILATKDYAEKHEIPYLAELVDStEV-------GIDPAIMgvSPIEAIKKLINRS 288
Cdd:PRK09268 246 PVFgkGGRATMTAGNSTPLTDGASVVLLASEEWAAEHGLPVLAYLVDA-ETaavdfvhGKEGLLM--APAYAVPRLLARN 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 289 ELELSDIDLFEINEAFAASSLAV----------NRELGLNE-------SQVNIYGGAIALGHAIGSSGSKILTTLSYALK 351
Cdd:PRK09268 323 GLTLQDFDFYEIHEAFASQVLATlkawedeeycRERLGLDAplgsidrSKLNVNGSSLAAGHPFAATGGRIVATLAKLLA 402
|
410
....*....|..
gi 2676378839 352 REQKRYGIASLC 363
Cdd:PRK09268 403 EKGSGRGLISIC 414
|
|
| Thiolase_C |
pfam02803 |
Thiolase, C-terminal domain; Thiolase is reported to be structurally related to beta-ketoacyl ... |
255-364 |
8.51e-43 |
|
Thiolase, C-terminal domain; Thiolase is reported to be structurally related to beta-ketoacyl synthase (pfam00109), and also chalcone synthase.
Pssm-ID: 397094 [Multi-domain] Cd Length: 123 Bit Score: 145.48 E-value: 8.51e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 255 PYLAELVDSTEVGIDPAIMGVSPIEAIKKLINRSELELSDIDLFEINEAFAASSLAVNRELGLNESQVNIYGGAIALGHA 334
Cdd:pfam02803 2 KPLARIRSYATAGVDPAIMGIGPAYAIPKALKKAGLTVNDIDLFEINEAFAAQALAVAKDLGIDPEKVNVNGGAIALGHP 81
|
90 100 110
....*....|....*....|....*....|
gi 2676378839 335 IGSSGSKILTTLSYALKREQKRYGIASLCI 364
Cdd:pfam02803 82 LGASGARILVTLLHELKRRGGKYGLASLCI 111
|
|
| SCP-x_thiolase |
cd00829 |
Thiolase domain associated with sterol carrier protein (SCP)-x isoform and related proteins; ... |
12-339 |
1.41e-18 |
|
Thiolase domain associated with sterol carrier protein (SCP)-x isoform and related proteins; SCP-2 has multiple roles in intracellular lipid circulation and metabolism. The N-terminal presequence in the SCP-x isoform represents a peroxisomal 3-ketacyl-Coa thiolase specific for branched-chain acyl CoAs, which is proteolytically cleaved from the sterol carrier protein.
Pssm-ID: 238425 [Multi-domain] Cd Length: 375 Bit Score: 86.16 E-value: 1.41e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 12 TPVGRYDGalaeYSAAELGTHVVSNLLSKHENIKSDVEQVIFGNVLQAGNGQNIARQIAIHSGLPNtVPASTINEVCGSG 91
Cdd:cd00829 6 TPFGRRSD----RSPLELAAEAARAALDDAGLEPADIDAVVVGNAAGGRFQSFPGALIAEYLGLLG-KPATRVEAAGASG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 92 MKAVILAKQLLQLGEAEVVIAGGTESMSNAPIIKNRKTQEETLSMLNDGLVDAFSGISM-GIIGETIAEQFDISRADQDA 170
Cdd:cd00829 81 SAAVRAAAAAIASGLADVVLVVGAEKMSDVPTGDEAGGRASDLEWEGPEPPGGLTPPALyALAARRYMHRYGTTREDLAK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 171 FAQNSQEKAVAASQAgIFKEEIvaigDVGVDETPRPSSSleklatlrtafkengTVTAGNSSPVNDGASAVILATKDYAE 250
Cdd:cd00829 161 VAVKNHRNAARNPYA-QFRKPI----TVEDVLNSRMIAD---------------PLRLLDCCPVSDGAAAVVLASEERAR 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 251 KHEIPY-----LAELVDSTEVGIDPAIMGVSPI-EAIKKLINRSELELSDIDLFEINEAFAASSLAVNRELGL---NESQ 321
Cdd:cd00829 221 ELTDRPvwilgVGAASDTPSLSERDDFLSLDAArLAARRAYKMAGITPDDIDVAELYDCFTIAELLALEDLGFcekGEGG 300
|
330 340 350
....*....|....*....|....*....|...
gi 2676378839 322 ---------------VNIYGGAIALGHAIGSSG 339
Cdd:cd00829 301 klvregdtaiggdlpVNTSGGLLSKGHPLGATG 333
|
|
| cond_enzymes |
cd00327 |
Condensing enzymes; Family of enzymes that catalyze a (decarboxylating or non-decarboxylating) ... |
45-355 |
1.34e-16 |
|
Condensing enzymes; Family of enzymes that catalyze a (decarboxylating or non-decarboxylating) Claisen-like condensation reaction. Members are share strong structural similarity, and are involved in the synthesis and degradation of fatty acids, and the production of polyketides, a diverse group of natural products.
Pssm-ID: 238201 [Multi-domain] Cd Length: 254 Bit Score: 78.64 E-value: 1.34e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 45 KSDVEQVIFGNVLQAGNGQNIARQIAIHSGLPNtVPASTINEVCGSGMKAVILAKQLLQLGEAEVVIAGGTEsmsnapii 124
Cdd:cd00327 26 KGPIVGVIVGTTGGSGEFSGAAGQLAYHLGISG-GPAYSVNQACATGLTALALAVQQVQNGKADIVLAGGSE-------- 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 125 knrktqeetlsmlndglvdafsgismgiigetiaeqfdisradqdafaqnsqekavaasqagifkeeivaigdvgvdetp 204
Cdd:cd00327 --------------------------------------------------------------------------------
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 205 rpsssleklatlrtafkengtvtagnSSPVNDGASAVILATKDYAEKHEIPYLAELVDSTEVGID----PAIMGVSPIEA 280
Cdd:cd00327 97 --------------------------EFVFGDGAAAAVVESEEHALRRGAHPQAEIVSTAATFDGasmvPAVSGEGLARA 150
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2676378839 281 IKKLINRSELELSDIDLFEINEAFAASSLAVNRELGLNESQV---NIYGGAIALGHAIGSSGSKILTTLSYALKREQK 355
Cdd:cd00327 151 ARKALEGAGLTPSDIDYVEAHGTGTPIGDAVELALGLDPDGVrspAVSATLIMTGHPLGAAGLAILDELLLMLEHEFI 228
|
|
| PRK06064 |
PRK06064 |
thiolase domain-containing protein; |
1-339 |
5.77e-11 |
|
thiolase domain-containing protein;
Pssm-ID: 235688 [Multi-domain] Cd Length: 389 Bit Score: 63.38 E-value: 5.77e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 1 MKEIVIIDALRTPVGRydgaLAEYSAAELGTHVVSNLLSKHENIKSDVEQVIFGNVLQAG-NGQ-NIARQIAIHSGLPNt 78
Cdd:PRK06064 1 MRDVAIIGVGQTKFGE----LWDVSLRDLAVEAGLEALEDAGIDGKDIDAMYVGNMSAGLfVSQeHIAALIADYAGLAP- 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 79 VPASTINEVCGSGMKAVILAKQLLQLGEAEVVIAGGTESMSNAPiiknRKTQEETLSMLNDGLVDAFSGISM----GIIG 154
Cdd:PRK06064 76 IPATRVEAACASGGAALRQAYLAVASGEADVVLAAGVEKMTDVP----TPDATEAIARAGDYEWEEFFGATFpglyALIA 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 155 ETIAEQFDISRADQDAFAQNSQEKAVAASQAgIFKEEIVaigdvgVDETPRPSSSLEKLATLrtafkengtvtagNSSPV 234
Cdd:PRK06064 152 RRYMHKYGTTEEDLALVAVKNHYNGSKNPYA-QFQKEIT------VEQVLNSPPVADPLKLL-------------DCSPI 211
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 235 NDGASAVILATKDYAEKH--EIPYlaelVDSTEVGIDPAIMGVSP--------IEAIKKLINRSELELSDIDLFEINEAF 304
Cdd:PRK06064 212 TDGAAAVILASEEKAKEYtdTPVW----IKASGQASDTIALHDRKdfttldaaVVAAEKAYKMAGIEPKDIDVAEVHDCF 287
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|...
gi 2676378839 305 AASSLAVNRELG----------LNESQ--------VNIYGGAIALGHAIGSSG 339
Cdd:PRK06064 288 TIAEILAYEDLGfakkgeggklAREGQtyiggdipVNPSGGLKAKGHPVGATG 340
|
|
| FabB |
COG0304 |
3-oxoacyl-(acyl-carrier-protein) synthase [Lipid transport and metabolism, Secondary ... |
65-124 |
1.38e-06 |
|
3-oxoacyl-(acyl-carrier-protein) synthase [Lipid transport and metabolism, Secondary metabolites biosynthesis, transport and catabolism]; 3-oxoacyl-(acyl-carrier-protein) synthase is part of the Pathway/BioSystem: Fatty acid biosynthesis
Pssm-ID: 440073 [Multi-domain] Cd Length: 409 Bit Score: 49.71 E-value: 1.38e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2676378839 65 IARQIAIHSGL--PNTVPASTinevCGSGMKAVILAKQLLQLGEAEVVIAGGTESMSNAPII 124
Cdd:COG0304 140 AAGHVSIRFGLkgPNYTVSTA----CASGAHAIGEAYRLIRRGRADVMIAGGAEAAITPLGL 197
|
|
| KAS_I_II |
cd00834 |
Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible ... |
65-124 |
1.47e-06 |
|
Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen condensation of malonyl-acyl carrier protein (ACP) with acyl-ACP.
Pssm-ID: 238430 [Multi-domain] Cd Length: 406 Bit Score: 49.84 E-value: 1.47e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 65 IARQIAIHSGLpnTVPASTINEVCGSGMKAVILAKQLLQLGEAEVVIAGGTESMSNAPII 124
Cdd:cd00834 140 AAGQVAIRLGL--RGPNYTVSTACASGAHAIGDAARLIRLGRADVVIAGGAEALITPLTL 197
|
|
| ketoacyl-synt |
pfam00109 |
Beta-ketoacyl synthase, N-terminal domain; The structure of beta-ketoacyl synthase is similar ... |
49-118 |
4.63e-04 |
|
Beta-ketoacyl synthase, N-terminal domain; The structure of beta-ketoacyl synthase is similar to that of the thiolase family (pfam00108) and also chalcone synthase. The active site of beta-ketoacyl synthase is located between the N and C-terminal domains. The N-terminal domain contains most of the structures involved in dimer formation and also the active site cysteine.
Pssm-ID: 425468 [Multi-domain] Cd Length: 251 Bit Score: 41.47 E-value: 4.63e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2676378839 49 EQVIFGNVLQAGNGQN-IARQIAIHSGLpnTVPASTINEVCGSGMKAVILAKQLLQLGEAEVVIAGGTESM 118
Cdd:pfam00109 135 GGPRRGSPFAVGTMPSvIAGRISYFLGL--RGPSVTVDTACSSSLVAIHAAVQSIRSGEADVALAGGVNLL 203
|
|
| PRK07314 |
PRK07314 |
beta-ketoacyl-ACP synthase II; |
65-121 |
9.16e-04 |
|
beta-ketoacyl-ACP synthase II;
Pssm-ID: 235987 [Multi-domain] Cd Length: 411 Bit Score: 40.93 E-value: 9.16e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 2676378839 65 IARQIAIHSGL--PNtvpaSTINEVCGSGMKAVILAKQLLQLGEAEVVIAGGTESMSNA 121
Cdd:PRK07314 141 AAGHVSIRYGAkgPN----HSIVTACATGAHAIGDAARLIAYGDADVMVAGGAEAAITP 195
|
|
| PRK07937 |
PRK07937 |
lipid-transfer protein; Provisional |
228-330 |
1.99e-03 |
|
lipid-transfer protein; Provisional
Pssm-ID: 181173 [Multi-domain] Cd Length: 352 Bit Score: 39.67 E-value: 1.99e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 228 AGNSSPVNDGASAVILATKDYAEKH-EIPylaELVDSTEVGIDPAIMGV-------SPIEAIKKLINRSeleLSDIDLFE 299
Cdd:PRK07937 198 RHDIAPITDGAAAVVLAAGDRARELrERP---AWITGIEHRIESPSLGArdltrspSTALAAEAATGGD---AGGVDVAE 271
|
90 100 110
....*....|....*....|....*....|..
gi 2676378839 300 INEAFAASSLAVNRELGLNES-QVNIYGGAIA 330
Cdd:PRK07937 272 LHAPFTHQELILREALGLGDKtKVNPSGGALA 303
|
|
| init_cond_enzymes |
cd00827 |
"initiating" condensing enzymes are a subclass of decarboxylating condensing enzymes, ... |
20-115 |
4.26e-03 |
|
"initiating" condensing enzymes are a subclass of decarboxylating condensing enzymes, including beta-ketoacyl [ACP] synthase, type III and polyketide synthases, type III, which include chalcone synthase and related enzymes. They are characterized by the utlization of CoA substrate primers, as well as the nature of their active site residues.
Pssm-ID: 238423 [Multi-domain] Cd Length: 324 Bit Score: 38.57 E-value: 4.26e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2676378839 20 ALAEYSAAELGTHVVSNLLSKHENIKSDVEQVIFGNVLQAGNGQNIARQIAIHSGLPNtVPASTINEVCGSGMKAVILAK 99
Cdd:cd00827 42 AGDDEDVPTMAVEAARRALERAGIDPDDIGLLIVATESPIDKGKSAATYLAELLGLTN-AEAFDLKQACYGGTAALQLAA 120
|
90
....*....|....*...
gi 2676378839 100 QLLQLGEAE--VVIAGGT 115
Cdd:cd00827 121 NLVESGPWRyaLVVASDI 138
|
|
| |
