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Conserved domains on  [gi|2680999625|ref|WP_333595308|]
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ATP-binding cassette domain-containing protein, partial [Anaerospora hongkongensis]

Protein Classification

ABC transporter ATP-binding protein( domain architecture ID 11438980)

ABC transporter ATP-binding protein is the ATPase catalytic subunit of an ABC transporter complex responsible for coupling the energy of ATP hydrolysis to the transport of one or more from a variety of substrates including hemin, bacitracin, and lipoproteins

CATH:  3.40.50.300
EC:  7.6.2.-
Gene Ontology:  GO:0042626|GO:0140359|GO:0016887|GO:0005524
PubMed:  25750732|24638992|9640644
SCOP:  4003976
TCDB:  3.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LolD COG1136
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];
2-140 5.28e-72

ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 440751 [Multi-domain]  Cd Length: 227  Bit Score: 214.91  E-value: 5.28e-72
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   2 SLLELKDVSMIYGS----VKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNSRNLTT 77
Cdd:COG1136     3 PLLELRNLTKSYGTgegeVTALRGVSLSIEAGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVLIDGQDISSLSERELAR 82

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2680999625  78 IRRDKVGLVFQQFHLVPYLTALENIMIAQYYHSMP---DEAEALAALDRVGLKDRAKHLPSQLSGG 140
Cdd:COG1136    83 LRRRHIGFVFQFFNLLPELTALENVALPLLLAGVSrkeRRERARELLERVGLGDRLDHRPSQLSGG 148
 
Name Accession Description Interval E-value
LolD COG1136
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];
2-140 5.28e-72

ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440751 [Multi-domain]  Cd Length: 227  Bit Score: 214.91  E-value: 5.28e-72
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   2 SLLELKDVSMIYGS----VKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNSRNLTT 77
Cdd:COG1136     3 PLLELRNLTKSYGTgegeVTALRGVSLSIEAGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVLIDGQDISSLSERELAR 82

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2680999625  78 IRRDKVGLVFQQFHLVPYLTALENIMIAQYYHSMP---DEAEALAALDRVGLKDRAKHLPSQLSGG 140
Cdd:COG1136    83 LRRRHIGFVFQFFNLLPELTALENVALPLLLAGVSrkeRRERARELLERVGLGDRLDHRPSQLSGG 148
ABC_MJ0796_LolCDE_FtsE cd03255
ATP-binding cassette domain of the transporters involved in export of lipoprotein and ...
 4-140 1.87e-66

ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.


Pssm-ID: 213222 [Multi-domain]  Cd Length: 218  Bit Score: 200.41  E-value: 1.87e-66
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   4 LELKDVSMIYGS----VKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNSRNLTTIR 79
Cdd:cd03255     1 IELKNLSKTYGGggekVQALKGVSLSIEKGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVRVDGTDISKLSEKELAAFR 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2680999625  80 RDKVGLVFQQFHLVPYLTALENIMIAQYYHSMP---DEAEALAALDRVGLKDRAKHLPSQLSGG 140
Cdd:cd03255    81 RRHIGFVFQSFNLLPDLTALENVELPLLLAGVPkkeRRERAEELLERVGLGDRLNHYPSELSGG 144
PRK10535 PRK10535
macrolide ABC transporter ATP-binding protein/permease MacB;
2-140 3.14e-41

macrolide ABC transporter ATP-binding protein/permease MacB;


Pssm-ID: 182528 [Multi-domain]  Cd Length: 648  Bit Score: 144.48  E-value: 3.14e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   2 SLLELKDVSMIY----GSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNSRNLTT 77
Cdd:PRK10535    3 ALLELKDIRRSYpsgeEQVEVLKGISLDIYAGEMVAIVGASGSGKSTLMNILGCLDKPTSGTYRVAGQDVATLDADALAQ 82

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2680999625  78 IRRDKVGLVFQQFHLVPYLTALENIMIAQYYHSMPDE---AEALAALDRVGLKDRAKHLPSQLSGG 140
Cdd:PRK10535   83 LRREHFGFIFQRYHLLSHLTAAQNVEVPAVYAGLERKqrlLRAQELLQRLGLEDRVEYQPSQLSGG 148
ABC_tran pfam00005
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ...
 19-140 5.66e-32

ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.


Pssm-ID: 394964 [Multi-domain]  Cd Length: 150  Bit Score: 110.82  E-value: 5.66e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625  19 LQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNSRnlttIRRDKVGLVFQQFHLVPYLTA 98
Cdd:pfam00005   1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQDLTDDERK----SLRKEIGYVFQDPQLFPRLTV 76

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 2680999625  99 LENIMIA---QYYHSMPDEAEALAALDRVGLKDRAKHL----PSQLSGG 140
Cdd:pfam00005  77 RENLRLGlllKGLSKREKDARAEEALEKLGLGDLADRPvgerPGTLSGG 125
ECF_ATPase_1 TIGR04520
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ...
 4-140 8.62e-29

energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the upstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 275313 [Multi-domain]  Cd Length: 268  Bit Score: 105.59  E-value: 8.62e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   4 LELKDVSMIY--GSVKALQNINLTVERGEWLAIMGPSGSGKTTLM-NIVGCMdKGTSGTVILDGedISTLNSRNLTTIRR 80
Cdd:TIGR04520   1 IEVENVSFSYpeSEKPALKNVSLSIEKGEFVAIIGHNGSGKSTLAkLLNGLL-LPTSGKVTVDG--LDTLDEENLWEIRK 77

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625  81 dKVGLVFQ----QF--HLVPYLTA--LENIMIAqyyhsmPDEAEAL--AALDRVGLKDRAKHLPSQLSGG 140
Cdd:TIGR04520  78 -KVGMVFQnpdnQFvgATVEDDVAfgLENLGVP------REEMRKRvdEALKLVGMEDFRDREPHLLSGG 140
GguA NF040905
sugar ABC transporter ATP-binding protein;
3-128 1.39e-16

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 74.83  E-value: 1.39e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   3 LLELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIV-GCMDKGT-SGTVILDGEdistlnSRNLTTIR- 79
Cdd:NF040905    1 ILEMRGITKTFPGVKALDDVNLSVREGEIHALCGENGAGKSTLMKVLsGVYPHGSyEGEILFDGE------VCRFKDIRd 74

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2680999625  80 RDKVGLVF--QQFHLVPYLTALENIM----IAQY----YHSMPDEAEALaaLDRVGLKD 128
Cdd:NF040905   75 SEALGIVIihQELALIPYLSIAENIFlgneRAKRgvidWNETNRRAREL--LAKVGLDE 131
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
5-140 2.04e-09

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 54.36  E-value: 2.04e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   5 ELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNivgcMDKG----TSGTVILDGEDIstlNSRNLTTIRR 80
Cdd:NF033858  268 EARGLTMRFGDFTAVDHVSFRIRRGEIFGFLGSNGCGKSTTMK----MLTGllpaSEGEAWLFGQPV---DAGDIATRRR 340

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2680999625  81 dkVGLVFQQFHLVPYLTALENIMI-AQYYHSMPDEAEAL--AALDRVGLKDRAKHLPSQLSGG 140
Cdd:NF033858  341 --VGYMSQAFSLYGELTVRQNLELhARLFHLPAAEIAARvaEMLERFDLADVADALPDSLPLG 401
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
5-68 2.05e-05

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 42.80  E-value: 2.05e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2680999625   5 ELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDIS 68
Cdd:NF033858    3 RLEGVSHRYGKTVALDDVSLDIPAGCMVGLIGPDGVGKSSLLSLIAGARKIQQGRVEVLGGDMA 66
GguA NF040905
sugar ABC transporter ATP-binding protein;
17-71 1.16e-04

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 40.54  E-value: 1.16e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2680999625  17 KALQNINLTVERGEWLAIMGPSGSGKTTL-MNIVG-CMDKGTSGTVILDGEDISTLN 71
Cdd:NF040905  274 KVVDDVSLNVRRGEIVGIAGLMGAGRTELaMSVFGrSYGRNISGTVFKDGKEVDVST 330
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 32-93 1.32e-04

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 39.66  E-value: 1.32e-04
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2680999625   32 LAIMGPSGSGKTTLMN-IVGCMDKGTSGTVILDGEDISTLNSRNLTTIRRDKVGLVFQQFHLV 93
Cdd:smart00382   5 ILIVGPPGSGKTTLARaLARELGPPGGGVIYIDGEDILEEVLDQLLLIIVGGKKASGSGELRL 67
 
Name Accession Description Interval E-value
LolD COG1136
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];
2-140 5.28e-72

ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440751 [Multi-domain]  Cd Length: 227  Bit Score: 214.91  E-value: 5.28e-72
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   2 SLLELKDVSMIYGS----VKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNSRNLTT 77
Cdd:COG1136     3 PLLELRNLTKSYGTgegeVTALRGVSLSIEAGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVLIDGQDISSLSERELAR 82

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2680999625  78 IRRDKVGLVFQQFHLVPYLTALENIMIAQYYHSMP---DEAEALAALDRVGLKDRAKHLPSQLSGG 140
Cdd:COG1136    83 LRRRHIGFVFQFFNLLPELTALENVALPLLLAGVSrkeRRERARELLERVGLGDRLDHRPSQLSGG 148
ABC_MJ0796_LolCDE_FtsE cd03255
ATP-binding cassette domain of the transporters involved in export of lipoprotein and ...
 4-140 1.87e-66

ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.


Pssm-ID: 213222 [Multi-domain]  Cd Length: 218  Bit Score: 200.41  E-value: 1.87e-66
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   4 LELKDVSMIYGS----VKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNSRNLTTIR 79
Cdd:cd03255     1 IELKNLSKTYGGggekVQALKGVSLSIEKGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVRVDGTDISKLSEKELAAFR 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2680999625  80 RDKVGLVFQQFHLVPYLTALENIMIAQYYHSMP---DEAEALAALDRVGLKDRAKHLPSQLSGG 140
Cdd:cd03255    81 RRHIGFVFQSFNLLPDLTALENVELPLLLAGVPkkeRRERAEELLERVGLGDRLNHYPSELSGG 144
GlnQ COG1126
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and ...
 3-140 5.74e-52

ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 440743 [Multi-domain]  Cd Length: 239  Bit Score: 164.40  E-value: 5.74e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   3 LLELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDIsTLNSRNLTTIRRdK 82
Cdd:COG1126     1 MIEIENLHKSFGDLEVLKGISLDVEKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTITVDGEDL-TDSKKDINKLRR-K 78

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2680999625  83 VGLVFQQFHLVPYLTALENIMIAQYY-HSMP-DEAE--ALAALDRVGLKDRAKHLPSQLSGG 140
Cdd:COG1126    79 VGMVFQQFNLFPHLTVLENVTLAPIKvKKMSkAEAEerAMELLERVGLADKADAYPAQLSGG 140
YbbA COG4181
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase ...
 2-140 1.57e-51

Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443338 [Multi-domain]  Cd Length: 233  Bit Score: 162.99  E-value: 1.57e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   2 SLLELKDVSMIY----GSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNSRNLTT 77
Cdd:COG4181     7 PIIELRGLTKTVgtgaGELTILKGISLEVEAGESVAIVGASGSGKSTLLGLLAGLDRPTSGTVRLAGQDLFALDEDARAR 86

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2680999625  78 IRRDKVGLVFQQFHLVPYLTALENIMIAQYYHSMPD-EAEALAALDRVGLKDRAKHLPSQLSGG 140
Cdd:COG4181    87 LRARHVGFVFQSFQLLPTLTALENVMLPLELAGRRDaRARARALLERVGLGHRLDHYPAQLSGG 150
TauB COG1116
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion ...
 1-140 2.03e-46

ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440733 [Multi-domain]  Cd Length: 260  Bit Score: 151.01  E-value: 2.03e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   1 MSLLELKDVSMIY----GSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNSRnlt 76
Cdd:COG1116     5 APALELRGVSKRFptggGGVTALDDVSLTVAAGEFVALVGPSGCGKSTLLRLIAGLEKPTSGEVLVDGKPVTGPGPD--- 81

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2680999625  77 tirrdkVGLVFQQFHLVPYLTALENIMIAQYYHSMP---DEAEALAALDRVGLKDRAKHLPSQLSGG 140
Cdd:COG1116    82 ------RGVVFQEPALLPWLTVLDNVALGLELRGVPkaeRRERARELLELVGLAGFEDAYPHQLSGG 142
FtsE COG2884
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];
4-140 2.85e-46

Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442130 [Multi-domain]  Cd Length: 223  Bit Score: 149.43  E-value: 2.85e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   4 LELKDVSMIY-GSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNSRNLTTIRRdK 82
Cdd:COG2884     2 IRFENVSKRYpGGREALSDVSLEIEKGEFVFLTGPSGAGKSTLLKLLYGEERPTSGQVLVNGQDLSRLKRREIPYLRR-R 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2680999625  83 VGLVFQQFHLVPYLTALENIMIAQYYHSMPDE---AEALAALDRVGLKDRAKHLPSQLSGG 140
Cdd:COG2884    81 IGVVFQDFRLLPDRTVYENVALPLRVTGKSRKeirRRVREVLDLVGLSDKAKALPHELSGG 141
ABC_HisP_GlnQ cd03262
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ...
 4-140 8.47e-46

ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.


Pssm-ID: 213229 [Multi-domain]  Cd Length: 213  Bit Score: 148.06  E-value: 8.47e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   4 LELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDIsTLNSRNLTTIRRdKV 83
Cdd:cd03262     1 IEIKNLHKSFGDFHVLKGIDLTVKKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTIIIDGLKL-TDDKKNINELRQ-KV 78

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2680999625  84 GLVFQQFHLVPYLTALENIMIAQ-YYHSMP-DEAEALA--ALDRVGLKDRAKHLPSQLSGG 140
Cdd:cd03262    79 GMVFQQFNLFPHLTVLENITLAPiKVKGMSkAEAEERAleLLEKVGLADKADAYPAQLSGG 139
ABC_NrtD_SsuB_transporters cd03293
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ...
 4-140 1.92e-43

ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213260 [Multi-domain]  Cd Length: 220  Bit Score: 142.23  E-value: 1.92e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   4 LELKDVSMIYGS----VKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNSRnlttir 79
Cdd:cd03293     1 LEVRNVSKTYGGgggaVTALEDISLSVEEGEFVALVGPSGCGKSTLLRIIAGLERPTSGEVLVDGEPVTGPGPD------ 74

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2680999625  80 rdkVGLVFQQFHLVPYLTALENIMIAQYYHSMPD---EAEALAALDRVGLKDRAKHLPSQLSGG 140
Cdd:cd03293    75 ---RGYVFQQDALLPWLTVLDNVALGLELQGVPKaeaRERAEELLELVGLSGFENAYPHQLSGG 135
PRK10535 PRK10535
macrolide ABC transporter ATP-binding protein/permease MacB;
2-140 3.14e-41

macrolide ABC transporter ATP-binding protein/permease MacB;


Pssm-ID: 182528 [Multi-domain]  Cd Length: 648  Bit Score: 144.48  E-value: 3.14e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   2 SLLELKDVSMIY----GSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNSRNLTT 77
Cdd:PRK10535    3 ALLELKDIRRSYpsgeEQVEVLKGISLDIYAGEMVAIVGASGSGKSTLMNILGCLDKPTSGTYRVAGQDVATLDADALAQ 82

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2680999625  78 IRRDKVGLVFQQFHLVPYLTALENIMIAQYYHSMPDE---AEALAALDRVGLKDRAKHLPSQLSGG 140
Cdd:PRK10535   83 LRREHFGFIFQRYHLLSHLTAAQNVEVPAVYAGLERKqrlLRAQELLQRLGLEDRVEYQPSQLSGG 148
MlaF COG1127
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ...
 3-140 3.44e-40

ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440744 [Multi-domain]  Cd Length: 241  Bit Score: 134.34  E-value: 3.44e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   3 LLELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLM-NIVGCMdKGTSGTVILDGEDISTLNSRNLTTIRRd 81
Cdd:COG1127     5 MIEVRNLTKSFGDRVVLDGVSLDVPRGEILAIIGGSGSGKSVLLkLIIGLL-RPDSGEILVDGQDITGLSEKELYELRR- 82

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2680999625  82 KVGLVFQQFHLVPYLTALENIMIAQYYHSMPDEAE----ALAALDRVGLKDRAKHLPSQLSGG 140
Cdd:COG1127    83 RIGMLFQGGALFDSLTVFENVAFPLREHTDLSEAEirelVLEKLELVGLPGAADKMPSELSGG 145
ABC_MetN_methionine_transporter cd03258
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ...
 3-140 7.24e-40

ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213225 [Multi-domain]  Cd Length: 233  Bit Score: 133.48  E-value: 7.24e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   3 LLELKDVSMIYGS----VKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNSRNLTTI 78
Cdd:cd03258     1 MIELKNVSKVFGDtggkVTALKDVSLSVPKGEIFGIIGRSGAGKSTLIRCINGLERPTSGSVLVDGTDLTLLSGKELRKA 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2680999625  79 RRdKVGLVFQQFHLVPYLTALENIMIAQYYHSMPD---EAEALAALDRVGLKDRAKHLPSQLSGG 140
Cdd:cd03258    81 RR-RIGMIFQHFNLLSSRTVFENVALPLEIAGVPKaeiEERVLELLELVGLEDKADAYPAQLSGG 144
AbcC COG1135
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];
4-140 2.05e-39

ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 440750 [Multi-domain]  Cd Length: 339  Bit Score: 134.82  E-value: 2.05e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   4 LELKDVSMIY----GSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNSRNLTTIR 79
Cdd:COG1135     2 IELENLSKTFptkgGPVTALDDVSLTIEKGEIFGIIGYSGAGKSTLIRCINLLERPTSGSVLVDGVDLTALSERELRAAR 81

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2680999625  80 RdKVGLVFQQFHLVPYLTALENIMIAQYYHSMP-DEAEALAA--LDRVGLKDRAKHLPSQLSGG 140
Cdd:COG1135    82 R-KIGMIFQHFNLLSSRTVAENVALPLEIAGVPkAEIRKRVAelLELVGLSDKADAYPSQLSGG 144
PotA COG3842
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ...
 1-140 3.11e-39

ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443052 [Multi-domain]  Cd Length: 353  Bit Score: 134.84  E-value: 3.11e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   1 MSLLELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDIStlnsrNLTTIRR 80
Cdd:COG3842     3 MPALELENVSKRYGDVTALDDVSLSIEPGEFVALLGPSGCGKTTLLRMIAGFETPDSGRILLDGRDVT-----GLPPEKR 77

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2680999625  81 DkVGLVFQQFHLVPYLTALENIMIAQYYHSMP-DEAEALA--ALDRVGLKDRAKHLPSQLSGG 140
Cdd:COG3842    78 N-VGMVFQDYALFPHLTVAENVAFGLRMRGVPkAEIRARVaeLLELVGLEGLADRYPHQLSGG 139
glnQ PRK09493
glutamine ABC transporter ATP-binding protein GlnQ;
3-140 4.80e-39

glutamine ABC transporter ATP-binding protein GlnQ;


Pssm-ID: 181906 [Multi-domain]  Cd Length: 240  Bit Score: 131.37  E-value: 4.80e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   3 LLELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTlNSRNLTTIRRDk 82
Cdd:PRK09493    1 MIEFKNVSKHFGPTQVLHNIDLNIDQGEVVVIIGPSGSGKSTLLRCINKLEEITSGDLIVDGLKVND-PKVDERLIRQE- 78

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2680999625  83 VGLVFQQFHLVPYLTALENIMIA--QYYHSMPDEAEALAA--LDRVGLKDRAKHLPSQLSGG 140
Cdd:PRK09493   79 AGMVFQQFYLFPHLTALENVMFGplRVRGASKEEAEKQARelLAKVGLAERAHHYPSELSGG 140
ABC_Carb_Solutes_like cd03259
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ...
 4-140 7.49e-39

ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213226 [Multi-domain]  Cd Length: 213  Bit Score: 130.33  E-value: 7.49e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   4 LELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLnsrnltTIRRDKV 83
Cdd:cd03259     1 LELKGLSKTYGSVRALDDLSLTVEPGEFLALLGPSGCGKTTLLRLIAGLERPDSGEILIDGRDVTGV------PPERRNI 74

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625  84 GLVFQQFHLVPYLTALENIMIAQYYHSMPDE---AEALAALDRVGLKDRAKHLPSQLSGG 140
Cdd:cd03259    75 GMVFQDYALFPHLTVAENIAFGLKLRGVPKAeirARVRELLELVGLEGLLNRYPHELSGG 134
ABC_PhnC_transporter cd03256
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ...
 4-140 2.31e-38

ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213223 [Multi-domain]  Cd Length: 241  Bit Score: 129.61  E-value: 2.31e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   4 LELKDVSMIYGS-VKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNSRNLTTIRRdK 82
Cdd:cd03256     1 IEVENLSKTYPNgKKALKDVSLSINPGEFVALIGPSGAGKSTLLRCLNGLVEPTSGSVLIDGTDINKLKGKALRQLRR-Q 79

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2680999625  83 VGLVFQQFHLVPYLTALENIMIAQY-YHS-------MPDEAE---ALAALDRVGLKDRAKHLPSQLSGG 140
Cdd:cd03256    80 IGMIFQQFNLIERLSVLENVLSGRLgRRStwrslfgLFPKEEkqrALAALERVGLLDKAYQRADQLSGG 148
CcmA COG1131
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
4-140 5.76e-37

ABC-type multidrug transport system, ATPase component [Defense mechanisms];


Pssm-ID: 440746 [Multi-domain]  Cd Length: 236  Bit Score: 125.95  E-value: 5.76e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   4 LELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDIstlnSRNLTTIRRdKV 83
Cdd:COG1131     1 IEVRGLTKRYGDKTALDGVSLTVEPGEIFGLLGPNGAGKTTTIRMLLGLLRPTSGEVRVLGEDV----ARDPAEVRR-RI 75

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625  84 GLVFQQFHLVPYLTALENI-MIAQYYHSMPDEAEALA--ALDRVGLKDRAKHLPSQLSGG 140
Cdd:COG1131    76 GYVPQEPALYPDLTVRENLrFFARLYGLPRKEARERIdeLLELFGLTDAADRKVGTLSGG 135
ABC_Org_Solvent_Resistant cd03261
ATP-binding cassette transport system involved in resistance to organic solvents; ABC ...
 4-140 1.70e-36

ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213228 [Multi-domain]  Cd Length: 235  Bit Score: 124.92  E-value: 1.70e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   4 LELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNSRNLTTIRRdKV 83
Cdd:cd03261     1 IELRGLTKSFGGRTVLKGVDLDVRRGEILAIIGPSGSGKSTLLRLIVGLLRPDSGEVLIDGEDISGLSEAELYRLRR-RM 79

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2680999625  84 GLVFQQFHLVPYLTALENIMIAQYYHSMPDEAE----ALAALDRVGLKDRAKHLPSQLSGG 140
Cdd:cd03261    80 GMLFQSGALFDSLTVFENVAFPLREHTRLSEEEireiVLEKLEAVGLRGAEDLYPAELSGG 140
ABC_Pro_Gly_Betaine cd03294
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This ...
 14-140 2.70e-36

ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This family comprises the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporters is the obligatory coupling of ATP hydrolysis to substrate translocation. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213261 [Multi-domain]  Cd Length: 269  Bit Score: 125.06  E-value: 2.70e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625  14 GSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNSRNLTTIRRDKVGLVFQQFHLV 93
Cdd:cd03294    35 GQTVGVNDVSLDVREGEIFVIMGLSGSGKSTLLRCINRLIEPTSGKVLIDGQDIAAMSRKELRELRRKKISMVFQSFALL 114

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 2680999625  94 PYLTALENIMIAQYYHSMPD---EAEALAALDRVGLKDRAKHLPSQLSGG 140
Cdd:cd03294   115 PHRTVLENVAFGLEVQGVPRaerEERAAEALELVGLEGWEHKYPDELSGG 164
ABC_FtsE cd03292
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ...
 4-140 1.06e-35

Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages


Pssm-ID: 213259 [Multi-domain]  Cd Length: 214  Bit Score: 122.13  E-value: 1.06e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   4 LELKDVSMIY-GSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNSRNLTTIRRdK 82
Cdd:cd03292     1 IEFINVTKTYpNGTAALDGINISISAGEFVFLVGPSGAGKSTLLKLIYKEELPTSGTIRVNGQDVSDLRGRAIPYLRR-K 79

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2680999625  83 VGLVFQQFHLVPYLTALENIMIAQ--YYHSMPDEAEAL-AALDRVGLKDRAKHLPSQLSGG 140
Cdd:cd03292    80 IGVVFQDFRLLPDRNVYENVAFALevTGVPPREIRKRVpAALELVGLSHKHRALPAELSGG 140
ABC_Mj1267_LivG_branched cd03219
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ...
 4-140 9.17e-35

ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).


Pssm-ID: 213186 [Multi-domain]  Cd Length: 236  Bit Score: 120.23  E-value: 9.17e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   4 LELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNSRNlttIRRDKV 83
Cdd:cd03219     1 LEVRGLTKRFGGLVALDDVSFSVRPGEIHGLIGPNGAGKTTLFNLISGFLRPTSGSVLFDGEDITGLPPHE---IARLGI 77

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625  84 GLVFQQFHLVPYLTALENIMIAQYYHSMPD-------------EAEALAALDRVGLKDRAKHLPSQLSGG 140
Cdd:cd03219    78 GRTFQIPRLFPELTVLENVMVAAQARTGSGlllararreereaRERAEELLERVGLADLADRPAGELSYG 147
CysA COG1118
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and ...
 1-140 4.68e-34

ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440735 [Multi-domain]  Cd Length: 348  Bit Score: 121.02  E-value: 4.68e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   1 MSLlELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTlnsrNLTTIRR 80
Cdd:COG1118     1 MSI-EVRNISKRFGSFTLLDDVSLEIASGELVALLGPSGSGKTTLLRIIAGLETPDSGRIVLNGRDLFT----NLPPRER 75

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2680999625  81 dKVGLVFQQFHLVPYLTALENIMIAqYYHSMPDEAEALAA----LDRVGLKDRAKHLPSQLSGG 140
Cdd:COG1118    76 -RVGFVFQHYALFPHMTVAENIAFG-LRVRPPSKAEIRARveelLELVQLEGLADRYPSQLSGG 137
GsiA COG1123
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ...
 3-140 9.50e-34

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440740 [Multi-domain]  Cd Length: 514  Bit Score: 123.09  E-value: 9.50e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   3 LLELKDVSMIY-----GSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNSRNLTT 77
Cdd:COG1123   260 LLEVRNLSKRYpvrgkGGVRAVDDVSLTLRRGETLGLVGESGSGKSTLARLLLGLLRPTSGSILFDGKDLTKLSRRSLRE 339

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625  78 IRRDkVGLVFQQ-FH-LVPYLTALENIMIAQYYHSMPDEAE----ALAALDRVGLKDRAKH-LPSQLSGG 140
Cdd:COG1123   340 LRRR-VQMVFQDpYSsLNPRMTVGDIIAEPLRLHGLLSRAErrerVAELLERVGLPPDLADrYPHELSGG 408
ABC_NikE_OppD_transporters cd03257
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ...
 3-140 6.30e-33

ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.


Pssm-ID: 213224 [Multi-domain]  Cd Length: 228  Bit Score: 115.30  E-value: 6.30e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   3 LLELKDVSMIY----GSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLnSRNLTTI 78
Cdd:cd03257     1 LLEVKNLSVSFptggGSVKALDDVSFSIKKGETLGLVGESGSGKSTLARAILGLLKPTSGSIIFDGKDLLKL-SRRLRKI 79

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625  79 RRDKVGLVFQ--QFHLVPYLTALENIMIAQYYHSMPDEAEA-----LAALDRVGL-KDRAKHLPSQLSGG 140
Cdd:cd03257    80 RRKEIQMVFQdpMSSLNPRMTIGEQIAEPLRIHGKLSKKEArkeavLLLLVGVGLpEEVLNRYPHELSGG 149
MalK COG3839
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism]; ...
 1-140 1.36e-32

ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism];


Pssm-ID: 443050 [Multi-domain]  Cd Length: 352  Bit Score: 117.48  E-value: 1.36e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   1 MSLLELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNSRnlttiRR 80
Cdd:COG3839     1 MASLELENVSKSYGGVEALKDIDLDIEDGEFLVLLGPSGCGKSTLLRMIAGLEDPTSGEILIGGRDVTDLPPK-----DR 75

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2680999625  81 DkVGLVFQQFHLVPYLTALENIMIAQYYHSMP-DEAEAL--AALDRVGLKDRAKHLPSQLSGG 140
Cdd:COG3839    76 N-IAMVFQSYALYPHMTVYENIAFPLKLRKVPkAEIDRRvrEAAELLGLEDLLDRKPKQLSGG 137
ABC_Class3 cd03229
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ...
 4-105 1.83e-32

ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213196 [Multi-domain]  Cd Length: 178  Bit Score: 112.67  E-value: 1.83e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   4 LELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNSRnlTTIRRDKV 83
Cdd:cd03229     1 LELKNVSKRYGQKTVLNDVSLNIEAGEIVALLGPSGSGKSTLLRCIAGLEEPDSGSILIDGEDLTDLEDE--LPPLRRRI 78

                          90       100
                  ....*....|....*....|..
gi 2680999625  84 GLVFQQFHLVPYLTALENIMIA 105
Cdd:cd03229    79 GMVFQDFALFPHLTVLENIALG 100
EcfA2 COG1122
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ...
 4-140 2.44e-32

Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];


Pssm-ID: 440739 [Multi-domain]  Cd Length: 230  Bit Score: 113.97  E-value: 2.44e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   4 LELKDVSMIY-GSVKALQNINLTVERGEWLAIMGPSGSGKTTL-MNIVGCMdKGTSGTVILDGEDIstlNSRNLTTIRRd 81
Cdd:COG1122     1 IELENLSFSYpGGTPALDDVSLSIEKGEFVAIIGPNGSGKSTLlRLLNGLL-KPTSGEVLVDGKDI---TKKNLRELRR- 75

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2680999625  82 KVGLVFQ----QFHlvpYLTALENIMIAQYYHSMP-DEAEALA--ALDRVGLKDRAKHLPSQLSGG 140
Cdd:COG1122    76 KVGLVFQnpddQLF---APTVEEDVAFGPENLGLPrEEIRERVeeALELVGLEHLADRPPHELSGG 138
ABC_tran pfam00005
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ...
 19-140 5.66e-32

ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.


Pssm-ID: 394964 [Multi-domain]  Cd Length: 150  Bit Score: 110.82  E-value: 5.66e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625  19 LQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNSRnlttIRRDKVGLVFQQFHLVPYLTA 98
Cdd:pfam00005   1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQDLTDDERK----SLRKEIGYVFQDPQLFPRLTV 76

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 2680999625  99 LENIMIA---QYYHSMPDEAEALAALDRVGLKDRAKHL----PSQLSGG 140
Cdd:pfam00005  77 RENLRLGlllKGLSKREKDARAEEALEKLGLGDLADRPvgerPGTLSGG 125
metN PRK11153
DL-methionine transporter ATP-binding subunit; Provisional
 5-140 1.47e-31

DL-methionine transporter ATP-binding subunit; Provisional


Pssm-ID: 236863 [Multi-domain]  Cd Length: 343  Bit Score: 114.51  E-value: 1.47e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   5 ELKDVSMIY----GSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNSRNLTTIRR 80
Cdd:PRK11153    3 ELKNISKVFpqggRTIHALNNVSLHIPAGEIFGVIGASGAGKSTLIRCINLLERPTSGRVLVDGQDLTALSEKELRKARR 82

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2680999625  81 dKVGLVFQQFHLVPYLTALENIMIAQYYHSMPD---EAEALAALDRVGLKDRAKHLPSQLSGG 140
Cdd:PRK11153   83 -QIGMIFQHFNLLSSRTVFDNVALPLELAGTPKaeiKARVTELLELVGLSDKADRYPAQLSGG 144
ABC_PotA_N cd03300
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ...
 4-140 2.23e-31

ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213267 [Multi-domain]  Cd Length: 232  Bit Score: 111.56  E-value: 2.23e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   4 LELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDIStlnsrNLTTIRRdKV 83
Cdd:cd03300     1 IELENVSKFYGGFVALDGVSLDIKEGEFFTLLGPSGCGKTTLLRLIAGFETPTSGEILLDGKDIT-----NLPPHKR-PV 74

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625  84 GLVFQQFHLVPYLTALENIMIAQYYHSMPD---EAEALAALDRVGLKDRAKHLPSQLSGG 140
Cdd:cd03300    75 NTVFQNYALFPHLTVFENIAFGLRLKKLPKaeiKERVAEALDLVQLEGYANRKPSQLSGG 134
YnjD COG4136
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function ...
 4-140 6.41e-31

ABC-type uncharacterized transport system YnjBCD, ATPase component [General function prediction only];


Pssm-ID: 443311 [Multi-domain]  Cd Length: 211  Bit Score: 109.88  E-value: 6.41e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   4 LELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMN-IVGCMDKG--TSGTVILDGEDISTLNsrnlttIRR 80
Cdd:COG4136     2 LSLENLTITLGGRPLLAPLSLTVAPGEILTLMGPSGSGKSTLLAaIAGTLSPAfsASGEVLLNGRRLTALP------AEQ 75

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2680999625  81 DKVGLVFQQFHLVPYLTALENIMIAqyyhsMPDE-------AEALAALDRVGLKDRAKHLPSQLSGG 140
Cdd:COG4136    76 RRIGILFQDDLLFPHLSVGENLAFA-----LPPTigraqrrARVEQALEEAGLAGFADRDPATLSGG 137
ABC_cobalt_CbiO_domain1 cd03225
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ...
 5-140 1.24e-30

First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.


Pssm-ID: 213192 [Multi-domain]  Cd Length: 211  Bit Score: 109.09  E-value: 1.24e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   5 ELKDVSMIYGS--VKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNSRNLttirRDK 82
Cdd:cd03225     1 ELKNLSFSYPDgaRPALDDISLTIKKGEFVLIVGPNGSGKSTLLRLLNGLLGPTSGEVLVDGKDLTKLSLKEL----RRK 76

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2680999625  83 VGLVFQ----QFHlvpYLTALENIMIAQYYHSMPDE---AEALAALDRVGLKDRAKHLPSQLSGG 140
Cdd:cd03225    77 VGLVFQnpddQFF---GPTVEEEVAFGLENLGLPEEeieERVEEALELVGLEGLRDRSPFTLSGG 138
ABC_CysA_sulfate_importer cd03296
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ...
 1-140 5.17e-30

ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213263 [Multi-domain]  Cd Length: 239  Bit Score: 108.20  E-value: 5.17e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   1 MSLlELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLnsrnltTIRR 80
Cdd:cd03296     1 MSI-EVRNVSKRFGDFVALDDVSLDIPSGELVALLGPSGSGKTTLLRLIAGLERPDSGTILFGGEDATDV------PVQE 73

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2680999625  81 DKVGLVFQQFHLVPYLTALENI---MIAQYYHSMPDEAE----ALAALDRVGLKDRAKHLPSQLSGG 140
Cdd:cd03296    74 RNVGFVFQHYALFRHMTVFDNVafgLRVKPRSERPPEAEirakVHELLKLVQLDWLADRYPAQLSGG 140
PRK10584 PRK10584
putative ABC transporter ATP-binding protein YbbA; Provisional
 19-140 5.94e-30

putative ABC transporter ATP-binding protein YbbA; Provisional


Pssm-ID: 182569 [Multi-domain]  Cd Length: 228  Bit Score: 107.94  E-value: 5.94e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625  19 LQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNSRNLTTIRRDKVGLVFQQFHLVPYLTA 98
Cdd:PRK10584   26 LTGVELVVKRGETIALIGESGSGKSTLLAILAGLDDGSSGEVSLVGQPLHQMDEEARAKLRAKHVGFVFQSFMLIPTLNA 105

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 2680999625  99 LENIMIAQYYHSMPD---EAEALAALDRVGLKDRAKHLPSQLSGG 140
Cdd:PRK10584  106 LENVELPALLRGESSrqsRNGAKALLEQLGLGKRLDHLPAQLSGG 150
lolD PRK11629
lipoprotein-releasing ABC transporter ATP-binding protein LolD;
15-140 1.42e-29

lipoprotein-releasing ABC transporter ATP-binding protein LolD;


Pssm-ID: 183244 [Multi-domain]  Cd Length: 233  Bit Score: 106.82  E-value: 1.42e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625  15 SVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNSRNLTTIRRDKVGLVFQQFHLVP 94
Cdd:PRK11629   21 QTDVLHNVSFSIGEGEMMAIVGSSGSGKSTLLHLLGGLDTPTSGDVIFNGQPMSKLSSAAKAELRNQKLGFIYQFHHLLP 100

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 2680999625  95 YLTALENI-MIAQYYHSMPDEAE--ALAALDRVGLKDRAKHLPSQLSGG 140
Cdd:PRK11629  101 DFTALENVaMPLLIGKKKPAEINsrALEMLAAVGLEHRANHRPSELSGG 149
DppD COG0444
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...
 3-140 1.99e-29

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440213 [Multi-domain]  Cd Length: 320  Bit Score: 108.60  E-value: 1.99e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   3 LLELKDVSMIY----GSVKALQNINLTVERGEWLAIMGPSGSGKTTLMN-IVGCMDKG--TSGTVILDGEDISTLNSRNL 75
Cdd:COG0444     1 LLEVRNLKVYFptrrGVVKAVDGVSFDVRRGETLGLVGESGSGKSTLARaILGLLPPPgiTSGEILFDGEDLLKLSEKEL 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2680999625  76 TTIRRDKVGLVFQ--QFHLVPYLTALENIMIAQYYHSMPDEAEALA----ALDRVGLKDRAKHL---PSQLSGG 140
Cdd:COG0444    81 RKIRGREIQMIFQdpMTSLNPVMTVGDQIAEPLRIHGGLSKAEAREraieLLERVGLPDPERRLdryPHELSGG 154
FetA COG4619
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];
4-140 7.01e-29

ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443661 [Multi-domain]  Cd Length: 209  Bit Score: 104.51  E-value: 7.01e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   4 LELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLnsrNLTTIRRdKV 83
Cdd:COG4619     1 LELEGLSFRVGGKPILSPVSLTLEAGECVAITGPSGSGKSTLLRALADLDPPTSGEIYLDGKPLSAM---PPPEWRR-QV 76

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2680999625  84 GLVFQQFHLVPYlTALENI-MIAQYYHSMPDEAEALAALDRVGLKDRAKHLP-SQLSGG 140
Cdd:COG4619    77 AYVPQEPALWGG-TVRDNLpFPFQLRERKFDRERALELLERLGLPPDILDKPvERLSGG 134
ECF_ATPase_1 TIGR04520
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ...
 4-140 8.62e-29

energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the upstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 275313 [Multi-domain]  Cd Length: 268  Bit Score: 105.59  E-value: 8.62e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   4 LELKDVSMIY--GSVKALQNINLTVERGEWLAIMGPSGSGKTTLM-NIVGCMdKGTSGTVILDGedISTLNSRNLTTIRR 80
Cdd:TIGR04520   1 IEVENVSFSYpeSEKPALKNVSLSIEKGEFVAIIGHNGSGKSTLAkLLNGLL-LPTSGKVTVDG--LDTLDEENLWEIRK 77

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625  81 dKVGLVFQ----QF--HLVPYLTA--LENIMIAqyyhsmPDEAEAL--AALDRVGLKDRAKHLPSQLSGG 140
Cdd:TIGR04520  78 -KVGMVFQnpdnQFvgATVEDDVAfgLENLGVP------REEMRKRvdEALKLVGMEDFRDREPHLLSGG 140
ABC_OpuCA_Osmoprotection cd03295
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ...
 4-140 6.17e-28

ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213262 [Multi-domain]  Cd Length: 242  Bit Score: 102.76  E-value: 6.17e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   4 LELKDVSMIYGSV-KALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNSRNLttirRDK 82
Cdd:cd03295     1 IEFENVTKRYGGGkKAVNNLNLEIAKGEFLVLIGPSGSGKTTTMKMINRLIEPTSGEIFIDGEDIREQDPVEL----RRK 76

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2680999625  83 VGLVFQQFHLVPYLTALENIMIA--------QYYHSMPDEAEALAALDRVGLKDRakhLPSQLSGG 140
Cdd:cd03295    77 IGYVIQQIGLFPHMTVEENIALVpkllkwpkEKIRERADELLALVGLDPAEFADR---YPHELSGG 139
artP PRK11124
arginine transporter ATP-binding subunit; Provisional
 1-140 9.53e-28

arginine transporter ATP-binding subunit; Provisional


Pssm-ID: 182980 [Multi-domain]  Cd Length: 242  Bit Score: 102.40  E-value: 9.53e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   1 MSLlELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNSRNLTTIR- 79
Cdd:PRK11124    1 MSI-QLNGINCFYGAHQALFDITLDCPQGETLVLLGPSGAGKSSLLRVLNLLEMPRSGTLNIAGNHFDFSKTPSDKAIRe 79

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2680999625  80 -RDKVGLVFQQFHLVPYLTALENIMIAQYYHSMPDEAEALAA----LDRVGLKDRAKHLPSQLSGG 140
Cdd:PRK11124   80 lRRNVGMVFQQYNLWPHLTVQQNLIEAPCRVLGLSKDQALARaeklLERLRLKPYADRFPLHLSGG 145
potA PRK09452
spermidine/putrescine ABC transporter ATP-binding protein PotA;
1-140 3.18e-27

spermidine/putrescine ABC transporter ATP-binding protein PotA;


Pssm-ID: 236523 [Multi-domain]  Cd Length: 375  Bit Score: 103.49  E-value: 3.18e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   1 MSLLELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDIStlnsrNLTTIRR 80
Cdd:PRK09452   12 SPLVELRGISKSFDGKEVISNLDLTINNGEFLTLLGPSGCGKTTVLRLIAGFETPDSGRIMLDGQDIT-----HVPAENR 86

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2680999625  81 DkVGLVFQQFHLVPYLTALENIMIAQYYHSMPD---EAEALAALDRVGLKDRAKHLPSQLSGG 140
Cdd:PRK09452   87 H-VNTVFQSYALFPHMTVFENVAFGLRMQKTPAaeiTPRVMEALRMVQLEEFAQRKPHQLSGG 148
MglA COG1129
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
3-126 7.44e-27

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440745 [Multi-domain]  Cd Length: 497  Bit Score: 103.94  E-value: 7.44e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   3 LLELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNSRnltTIRRDK 82
Cdd:COG1129     4 LLEMRGISKSFGGVKALDGVSLELRPGEVHALLGENGAGKSTLMKILSGVYQPDSGEILLDGEPVRFRSPR---DAQAAG 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 2680999625  83 VGLVFQQFHLVPYLTALENIMIAQYYHSMP--D----EAEALAALDRVGL 126
Cdd:COG1129    81 IAIIHQELNLVPNLSVAENIFLGREPRRGGliDwramRRRARELLARLGL 130
CcmA COG4133
ABC-type transport system involved in cytochrome c biogenesis, ATPase component ...
 3-140 9.09e-27

ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443308 [Multi-domain]  Cd Length: 206  Bit Score: 99.09  E-value: 9.09e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   3 LLELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNSRnlttiRRDK 82
Cdd:COG4133     2 MLEAENLSCRRGERLLFSGLSFTLAAGEALALTGPNGSGKTTLLRILAGLLPPSAGEVLWNGEPIRDARED-----YRRR 76

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2680999625  83 VGLVFQQFHLVPYLTALENI-MIAQYYHSMPDEAEALAALDRVGLKDRAKHLPSQLSGG 140
Cdd:COG4133    77 LAYLGHADGLKPELTVRENLrFWAALYGLRADREAIDEALEAVGLAGLADLPVRQLSAG 135
ThiQ COG3840
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];
4-140 1.78e-26

ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];


Pssm-ID: 443051 [Multi-domain]  Cd Length: 232  Bit Score: 98.67  E-value: 1.78e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   4 LELKDVSMIYGSvkALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNsrnlttIRRDKV 83
Cdd:COG3840     2 LRLDDLTYRYGD--FPLRFDLTIAAGERVAILGPSGAGKSTLLNLIAGFLPPDSGRILWNGQDLTALP------PAERPV 73

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2680999625  84 GLVFQQFHLVPYLTALENIMIAqyYH-----SMPDEAEALAALDRVGLKDRAKHLPSQLSGG 140
Cdd:COG3840    74 SMLFQENNLFPHLTVAQNIGLG--LRpglklTAEQRAQVEQALERVGLAGLLDRLPGQLSGG 133
GsiA COG1123
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ...
 1-140 1.97e-26

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440740 [Multi-domain]  Cd Length: 514  Bit Score: 102.67  E-value: 1.97e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   1 MS-LLELKDVSMIY--GSVKALQNINLTVERGEWLAIMGPSGSGKTTL-MNIVGCMDKG--TSGTVILDGEDISTLNSRn 74
Cdd:COG1123     1 MTpLLEVRDLSVRYpgGDVPAVDGVSLTIAPGETVALVGESGSGKSTLaLALMGLLPHGgrISGEVLLDGRDLLELSEA- 79

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2680999625  75 lttIRRDKVGLVFQQF--HLVPyLTALENIMIAQYYHSMPDE---AEALAALDRVGLKDRAKHLPSQLSGG 140
Cdd:COG1123    80 ---LRGRRIGMVFQDPmtQLNP-VTVGDQIAEALENLGLSRAearARVLELLEAVGLERRLDRYPHQLSGG 146
ABC_DR_subfamily_A cd03230
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ...
 4-102 2.78e-26

ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213197 [Multi-domain]  Cd Length: 173  Bit Score: 96.70  E-value: 2.78e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   4 LELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDIstlnSRNLTTIRRdKV 83
Cdd:cd03230     1 IEVRNLSKRYGKKTALDDISLTVEKGEIYGLLGPNGAGKTTLIKIILGLLKPDSGEIKVLGKDI----KKEPEEVKR-RI 75

                          90
                  ....*....|....*....
gi 2680999625  84 GLVFQQFHLVPYLTALENI 102
Cdd:cd03230    76 GYLPEEPSLYENLTVRENL 94
ABC_TM1139_LivF_branched cd03224
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ...
 4-140 6.88e-26

ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.


Pssm-ID: 213191 [Multi-domain]  Cd Length: 222  Bit Score: 97.12  E-value: 6.88e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   4 LELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMN-IVGcMDKGTSGTVILDGEDISTLNSRnltTIRRDK 82
Cdd:cd03224     1 LEVENLNAGYGKSQILFGVSLTVPEGEIVALLGRNGAGKTTLLKtIMG-LLPPRSGSIRFDGRDITGLPPH---ERARAG 76

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2680999625  83 VGLVFQQFHLVPYLTALENIMIAQYyhsMPDEAEALAALDRV-----GLKDRAKHLPSQLSGG 140
Cdd:cd03224    77 IGYVPEGRRIFPELTVEENLLLGAY---ARRRAKRKARLERVyelfpRLKERRKQLAGTLSGG 136
ZnuC COG1121
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ...
 1-140 7.33e-26

ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440738 [Multi-domain]  Cd Length: 245  Bit Score: 97.47  E-value: 7.33e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   1 MSLLELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMN-IVGcMDKGTSGTVILDGEDISTlnsrnlttiR 79
Cdd:COG1121     4 MPAIELENLTVSYGGRPVLEDVSLTIPPGEFVAIVGPNGAGKSTLLKaILG-LLPPTSGTVRLFGKPPRR---------A 73

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2680999625  80 RDKVGLVFQQFHL---VPyLTALENIMIAQYYH-------SMPDEAEALAALDRVGLKDRAKHLPSQLSGG 140
Cdd:COG1121    74 RRRIGYVPQRAEVdwdFP-ITVRDVVLMGRYGRrglfrrpSRADREAVDEALERVGLEDLADRPIGELSGG 143
CydC COG4987
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease ...
 4-140 9.83e-26

ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444011 [Multi-domain]  Cd Length: 569  Bit Score: 101.00  E-value: 9.83e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   4 LELKDVSMIY--GSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNSRNLttirRD 81
Cdd:COG4987   334 LELEDVSFRYpgAGRPVLDGLSLTLPPGERVAIVGPSGSGKSTLLALLLRFLDPQSGSITLGGVDLRDLDEDDL----RR 409

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2680999625  82 KVGLVFQQFHLVpYLTALENIMIAQyyhsmPD--EAEALAALDRVGLKDRAKHLP-----------SQLSGG 140
Cdd:COG4987   410 RIAVVPQRPHLF-DTTLRENLRLAR-----PDatDEELWAALERVGLGDWLAALPdgldtwlgeggRRLSGG 475
ABC_PstB_phosphate_transporter cd03260
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ...
 4-140 1.40e-25

ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).


Pssm-ID: 213227 [Multi-domain]  Cd Length: 227  Bit Score: 96.48  E-value: 1.40e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   4 LELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTL------MNIVGCMDKgTSGTVILDGEDISTLNSrNLTT 77
Cdd:cd03260     1 IELRDLNVYYGDKHALKDISLDIPKGEITALIGPSGCGKSTLlrllnrLNDLIPGAP-DEGEVLLDGKDIYDLDV-DVLE 78

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2680999625  78 IRRdKVGLVFQQFHLVPyLTALENIMIAQYYHSMPD----EAEALAALDRVGL----KDRAKhlPSQLSGG 140
Cdd:cd03260    79 LRR-RVGMVFQKPNPFP-GSIYDNVAYGLRLHGIKLkeelDERVEEALRKAALwdevKDRLH--ALGLSGG 145
ABC_Metallic_Cations cd03235
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ...
 5-140 2.31e-25

ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.


Pssm-ID: 213202 [Multi-domain]  Cd Length: 213  Bit Score: 95.68  E-value: 2.31e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   5 ELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMN-IVGCMdKGTSGTVILDGEDISTLNSRnlttirrdkV 83
Cdd:cd03235     1 EVEDLTVSYGGHPVLEDVSFEVKPGEFLAIVGPNGAGKSTLLKaILGLL-KPTSGSIRVFGKPLEKERKR---------I 70

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2680999625  84 GLVFQQFHLVPY--LTALENIMIAQYYH-------SMPDEAEALAALDRVGLKDRAKHLPSQLSGG 140
Cdd:cd03235    71 GYVPQRRSIDRDfpISVRDVVLMGLYGHkglfrrlSKADKAKVDEALERVGLSELADRQIGELSGG 136
NupO COG3845
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ...
 3-127 4.42e-25

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];


Pssm-ID: 443055 [Multi-domain]  Cd Length: 504  Bit Score: 98.95  E-value: 4.42e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   3 LLELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNSRNlttIRRDK 82
Cdd:COG3845     5 ALELRGITKRFGGVVANDDVSLTVRPGEIHALLGENGAGKSTLMKILYGLYQPDSGEILIDGKPVRIRSPRD---AIALG 81

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2680999625  83 VGLVFQQFHLVPYLTALENIMIAQ-----YYHSMPDEAEALAAL-DRVGLK 127
Cdd:COG3845    82 IGMVHQHFMLVPNLTVAENIVLGLeptkgGRLDRKAARARIRELsERYGLD 132
PRK10851 PRK10851
sulfate/thiosulfate ABC transporter ATP-binding protein CysA;
1-140 6.25e-25

sulfate/thiosulfate ABC transporter ATP-binding protein CysA;


Pssm-ID: 182778 [Multi-domain]  Cd Length: 353  Bit Score: 97.08  E-value: 6.25e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   1 MSLlELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNSRNlttiRR 80
Cdd:PRK10851    1 MSI-EIANIKKSFGRTQVLNDISLDIPSGQMVALLGPSGSGKTTLLRIIAGLEHQTSGHIRFHGTDVSRLHARD----RK 75

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2680999625  81 dkVGLVFQQFHLVPYLTALENI-----MIAQyyHSMPDEAE----ALAALDRVGLKDRAKHLPSQLSGG 140
Cdd:PRK10851   76 --VGFVFQHYALFRHMTVFDNIafgltVLPR--RERPNAAAikakVTQLLEMVQLAHLADRYPAQLSGG 140
SunT COG2274
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ...
 4-140 7.52e-25

ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];


Pssm-ID: 441875 [Multi-domain]  Cd Length: 711  Bit Score: 98.75  E-value: 7.52e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   4 LELKDVSMIYG--SVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNSRNLttirRD 81
Cdd:COG2274   474 IELENVSFRYPgdSPPVLDNISLTIKPGERVAIVGRSGSGKSTLLKLLLGLYEPTSGRILIDGIDLRQIDPASL----RR 549

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2680999625  82 KVGLVFQQfhlvPYL---TALENIMIAqyyHSMPDEAEALAALDRVGLKDRAKHLP-----------SQLSGG 140
Cdd:COG2274   550 QIGVVLQD----VFLfsgTIRENITLG---DPDATDEEIIEAARLAGLHDFIEALPmgydtvvgeggSNLSGG 615
PRK11831 PRK11831
phospholipid ABC transporter ATP-binding protein MlaF;
1-140 1.01e-24

phospholipid ABC transporter ATP-binding protein MlaF;


Pssm-ID: 236997 [Multi-domain]  Cd Length: 269  Bit Score: 95.22  E-value: 1.01e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   1 MSLLELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNSRNLTTIRR 80
Cdd:PRK11831    5 ANLVDMRGVSFTRGNRCIFDNISLTVPRGKITAIMGPSGIGKTTLLRLIGGQIAPDHGEILFDGENIPAMSRSRLYTVRK 84

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2680999625  81 dKVGLVFQQFHLVPYLTALENIMIAQYYHS-MPDE---AEALAALDRVGLKDRAKHLPSQLSGG 140
Cdd:PRK11831   85 -RMSMLFQSGALFTDMNVFDNVAYPLREHTqLPAPllhSTVMMKLEAVGLRGAAKLMPSELSGG 147
ABC_MalK_N cd03301
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ...
 4-140 2.48e-24

The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.


Pssm-ID: 213268 [Multi-domain]  Cd Length: 213  Bit Score: 92.70  E-value: 2.48e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   4 LELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTL--NSRNlttirrd 81
Cdd:cd03301     1 VELENVTKRFGNVTALDDLNLDIADGEFVVLLGPSGCGKTTTLRMIAGLEEPTSGRIYIGGRDVTDLppKDRD------- 73

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2680999625  82 kVGLVFQQFHLVPYLTALENIMIAQYYHSMPDEA------EALAALDRVGLKDRakhLPSQLSGG 140
Cdd:cd03301    74 -IAMVFQNYALYPHMTVYDNIAFGLKLRKVPKDEidervrEVAELLQIEHLLDR---KPKQLSGG 134
livG PRK11300
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional
 3-140 3.04e-24

leucine/isoleucine/valine transporter ATP-binding subunit; Provisional


Pssm-ID: 183080 [Multi-domain]  Cd Length: 255  Bit Score: 93.52  E-value: 3.04e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   3 LLELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNSRNlttIRRDK 82
Cdd:PRK11300    5 LLSVSGLMMRFGGLLAVNNVNLEVREQEIVSLIGPNGAGKTTVFNCLTGFYKPTGGTILLRGQHIEGLPGHQ---IARMG 81

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2680999625  83 VGLVFQQFHLVPYLTALENIMIAQYYHS----------MPD----EAEAL--AA--LDRVGLKDRAKHLPSQLSGG 140
Cdd:PRK11300   82 VVRTFQHVRLFREMTVIENLLVAQHQQLktglfsgllkTPAfrraESEALdrAAtwLERVGLLEHANRQAGNLAYG 157
MdlB COG1132
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];
4-140 3.30e-24

ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];


Pssm-ID: 440747 [Multi-domain]  Cd Length: 579  Bit Score: 96.77  E-value: 3.30e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   4 LELKDVSMIY-GSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNSRNLttirRDK 82
Cdd:COG1132   340 IEFENVSFSYpGDRPVLKDISLTIPPGETVALVGPSGSGKSTLVNLLLRFYDPTSGRILIDGVDIRDLTLESL----RRQ 415

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2680999625  83 VGLVFQQFHLVpYLTALENIMIAQyyhsmPD--EAEALAALDRVGLKDRAKHLP-----------SQLSGG 140
Cdd:COG1132   416 IGVVPQDTFLF-SGTIRENIRYGR-----PDatDEEVEEAAKAAQAHEFIEALPdgydtvvgergVNLSGG 480
PstB COG1117
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; ...
 4-140 5.82e-24

ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440734 [Multi-domain]  Cd Length: 258  Bit Score: 92.79  E-value: 5.82e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   4 LELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTL------MN--IVGCmdkGTSGTVILDGEDISTlNSRNL 75
Cdd:COG1117    12 IEVRNLNVYYGDKQALKDINLDIPENKVTALIGPSGCGKSTLlrclnrMNdlIPGA---RVEGEILLDGEDIYD-PDVDV 87

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2680999625  76 TTIRRdKVGLVFQQ---FHLVPYltalENIMIAQYYHSMPDEAEaLA-----ALDRVGL----KDRAKHLPSQLSGG 140
Cdd:COG1117    88 VELRR-RVGMVFQKpnpFPKSIY----DNVAYGLRLHGIKSKSE-LDeiveeSLRKAALwdevKDRLKKSALGLSGG 158
PRK11264 PRK11264
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional
 1-140 7.37e-24

putative amino-acid ABC transporter ATP-binding protein YecC; Provisional


Pssm-ID: 183063 [Multi-domain]  Cd Length: 250  Bit Score: 92.51  E-value: 7.37e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   1 MSLLELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDgeDISTLNSRNL----T 76
Cdd:PRK11264    1 MSAIEVKNLVKKFHGQTVLHGIDLEVKPGEVVAIIGPSGSGKTTLLRCINLLEQPEAGTIRVG--DITIDTARSLsqqkG 78

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2680999625  77 TIR--RDKVGLVFQQFHLVPYLTALENIM----IAQyyhSMP-DEAEALAA--LDRVGLKDRAKHLPSQLSGG 140
Cdd:PRK11264   79 LIRqlRQHVGFVFQNFNLFPHRTVLENIIegpvIVK---GEPkEEATARARelLAKVGLAGKETSYPRRLSGG 148
ABC_drug_resistance_like cd03264
ABC-type multidrug transport system, ATPase component; The biological function of this family ...
 4-140 9.15e-24

ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213231 [Multi-domain]  Cd Length: 211  Bit Score: 91.49  E-value: 9.15e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   4 LELKDVSMIYGSVKALQNINLTVERGEWlAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDIstlnSRNLTTIRRdKV 83
Cdd:cd03264     1 LQLENLTKRYGKKRALDGVSLTLGPGMY-GLLGPNGAGKTTLMRILATLTPPSSGTIRIDGQDV----LKQPQKLRR-RI 74

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625  84 GLVFQQFHLVPYLTALENIMIAQYYHSMPD---EAEALAALDRVGLKDRAKHLPSQLSGG 140
Cdd:cd03264    75 GYLPQEFGVYPNFTVREFLDYIAWLKGIPSkevKARVDEVLELVNLGDRAKKKIGSLSGG 134
ABCC_MRP_Like cd03228
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ...
 4-102 2.05e-23

ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213195 [Multi-domain]  Cd Length: 171  Bit Score: 89.36  E-value: 2.05e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   4 LELKDVSMIYGS--VKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNSRNLttirRD 81
Cdd:cd03228     1 IEFKNVSFSYPGrpKPVLKDVSLTIKPGEKVAIVGPSGSGKSTLLKLLLRLYDPTSGEILIDGVDLRDLDLESL----RK 76

                          90       100
                  ....*....|....*....|.
gi 2680999625  82 KVGLVFQQFHLVPyLTALENI 102
Cdd:cd03228    77 NIAYVPQDPFLFS-GTIRENI 96
CydD COG4988
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease ...
 4-140 6.25e-23

ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444012 [Multi-domain]  Cd Length: 563  Bit Score: 92.90  E-value: 6.25e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   4 LELKDVSMIY-GSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNSRNLttirRDK 82
Cdd:COG4988   337 IELEDVSFSYpGGRPALDGLSLTIPPGERVALVGPSGAGKSTLLNLLLGFLPPYSGSILINGVDLSDLDPASW----RRQ 412

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2680999625  83 VGLVFQQfhlvPYL---TALENIMIAQyyhSMPDEAEALAALDRVGLKDRAKHLP-----------SQLSGG 140
Cdd:COG4988   413 IAWVPQN----PYLfagTIRENLRLGR---PDASDEELEAALEAAGLDEFVAALPdgldtplgeggRGLSGG 477
ABC_ATPase cd00267
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ...
 5-88 7.63e-23

ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213179 [Multi-domain]  Cd Length: 157  Bit Score: 87.69  E-value: 7.63e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   5 ELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNSRNLttirRDKVG 84
Cdd:cd00267     1 EIENLSFRYGGRTALDNVSLTLKAGEIVALVGPNGSGKSTLLRAIAGLLKPTSGEILIDGKDIAKLPLEEL----RRRIG 76


                  ....
gi 2680999625  85 LVFQ 88
Cdd:cd00267    77 YVPQ 80
ABC_subfamily_A cd03263
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ...
 4-140 4.00e-22

ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.


Pssm-ID: 213230 [Multi-domain]  Cd Length: 220  Bit Score: 87.18  E-value: 4.00e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   4 LELKDVSMIYGS--VKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTlnsrNLTTIRRd 81
Cdd:cd03263     1 LQIRNLTKTYKKgtKPAVDDLSLNVYKGEIFGLLGHNGAGKTTTLKMLTGELRPTSGTAYINGYSIRT----DRKAARQ- 75

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2680999625  82 KVGLVFQQFHLVPYLTALENImiaqYYHSM-------PDEAEALAALDRVGLKDRAKHLPSQLSGG 140
Cdd:cd03263    76 SLGYCPQFDALFDELTVREHL----RFYARlkglpksEIKEEVELLLRVLGLTDKANKRARTLSGG 137
ABC_ThiQ_thiamine_transporter cd03298
ATP-binding cassette domain of the thiamine transport system; Part of the ...
 4-140 6.36e-22

ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213265 [Multi-domain]  Cd Length: 211  Bit Score: 86.78  E-value: 6.36e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   4 LELKDVSMIYGSvkALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNsrnlttIRRDKV 83
Cdd:cd03298     1 VRLDKIRFSYGE--QPMHFDLTFAQGEITAIVGPSGSGKSTLLNLIAGFETPQSGRVLINGVDVTAAP------PADRPV 72

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625  84 GLVFQQFHLVPYLTALENIMIAQY--YHSMPDEAEAL-AALDRVGLKDRAKHLPSQLSGG 140
Cdd:cd03298    73 SMLFQENNLFAHLTVEQNVGLGLSpgLKLTAEDRQAIeVALARVGLAGLEKRLPGELSGG 132
PRK10070 PRK10070
proline/glycine betaine ABC transporter ATP-binding protein ProV;
18-140 7.81e-22

proline/glycine betaine ABC transporter ATP-binding protein ProV;


Pssm-ID: 182221 [Multi-domain]  Cd Length: 400  Bit Score: 89.32  E-value: 7.81e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625  18 ALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNSRNLTTIRRDKVGLVFQQFHLVPYLT 97
Cdd:PRK10070   43 GVKDASLAIEEGEIFVIMGLSGSGKSTMVRLLNRLIEPTRGQVLIDGVDIAKISDAELREVRRKKIAMVFQSFALMPHMT 122

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 2680999625  98 ALENIMIAQYYHSMPDE---AEALAALDRVGLKDRAKHLPSQLSGG 140
Cdd:PRK10070  123 VLDNTAFGMELAGINAEerrEKALDALRQVGLENYAHSYPDELSGG 168
YejF COG4172
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ...
 1-140 9.35e-22

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443332 [Multi-domain]  Cd Length: 533  Bit Score: 89.74  E-value: 9.35e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   1 MSLLELKDVSMIYGS----VKALQNINLTVERGEWLAIMGPSGSGKT-TLMNIVGCMDKG---TSGTVILDGEDISTLNS 72
Cdd:COG4172     4 MPLLSVEDLSVAFGQgggtVEAVKGVSFDIAAGETLALVGESGSGKSvTALSILRLLPDPaahPSGSILFDGQDLLGLSE 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625  73 RNLTTIRRDKVGLVFQQfhlvPyLTAL-----------ENIMIAQyyhSMPDEA---EALAALDRVGLKD---RAKHLPS 135
Cdd:COG4172    84 RELRRIRGNRIAMIFQE----P-MTSLnplhtigkqiaEVLRLHR---GLSGAAaraRALELLERVGIPDperRLDAYPH 155


                  ....*
gi 2680999625 136 QLSGG 140
Cdd:COG4172   156 QLSGG 160
tauB PRK11248
taurine ABC transporter ATP-binding subunit;
3-140 1.52e-21

taurine ABC transporter ATP-binding subunit;


Pssm-ID: 183056 [Multi-domain]  Cd Length: 255  Bit Score: 86.68  E-value: 1.52e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   3 LLELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNSRNlttirrdk 82
Cdd:PRK11248    1 MLQISHLYADYGGKPALEDINLTLESGELLVVLGPSGCGKTTLLNLIAGFVPYQHGSITLDGKPVEGPGAER-------- 72

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2680999625  83 vGLVFQQFHLVPYLTALENIMIAQYYHSMPD---EAEALAALDRVGLKDRAKHLPSQLSGG 140
Cdd:PRK11248   73 -GVVFQNEGLLPWRNVQDNVAFGLQLAGVEKmqrLEIAHQMLKKVGLEGAEKRYIWQLSGG 132
fbpC PRK11432
ferric ABC transporter ATP-binding protein;
2-140 1.56e-21

ferric ABC transporter ATP-binding protein;


Pssm-ID: 183133 [Multi-domain]  Cd Length: 351  Bit Score: 87.85  E-value: 1.56e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   2 SLLELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTlnsrnlTTIRRD 81
Cdd:PRK11432    5 NFVVLKNITKRFGSNTVIDNLNLTIKQGTMVTLLGPSGCGKTTVLRLVAGLEKPTEGQIFIDGEDVTH------RSIQQR 78

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2680999625  82 KVGLVFQQFHLVPYLTALENIMIAQYYHSMPDE------AEALAALDRVGLKDRakhLPSQLSGG 140
Cdd:PRK11432   79 DICMVFQSYALFPHMSLGENVGYGLKMLGVPKEerkqrvKEALELVDLAGFEDR---YVDQISGG 140
PRK10908 PRK10908
cell division ATP-binding protein FtsE;
3-140 4.83e-21

cell division ATP-binding protein FtsE;


Pssm-ID: 182829 [Multi-domain]  Cd Length: 222  Bit Score: 84.54  E-value: 4.83e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   3 LLELKDVSMIY-GSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNSRNLTTIRRd 81
Cdd:PRK10908    1 MIRFEHVSKAYlGGRQALQGVTFHMRPGEMAFLTGHSGAGKSTLLKLICGIERPSAGKIWFSGHDITRLKNREVPFLRR- 79

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2680999625  82 KVGLVFQQFHLVPYLTALENIMIAQYYHSMPDE---AEALAALDRVGLKDRAKHLPSQLSGG 140
Cdd:PRK10908   80 QIGMIFQDHHLLMDRTVYDNVAIPLIIAGASGDdirRRVSAALDKVGLLDKAKNFPIQLSGG 141
PRK10247 PRK10247
putative ABC transporter ATP-binding protein YbbL; Provisional
 3-140 2.12e-20

putative ABC transporter ATP-binding protein YbbL; Provisional


Pssm-ID: 182331 [Multi-domain]  Cd Length: 225  Bit Score: 82.84  E-value: 2.12e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   3 LLELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNSRnlttIRRDK 82
Cdd:PRK10247    7 LLQLQNVGYLAGDAKILNNISFSLRAGEFKLITGPSGCGKSTLLKIVASLISPTSGTLLFEGEDISTLKPE----IYRQQ 82

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2680999625  83 VGLVFQqfhlVPYL---TALENIMIA-QYYHSMPDEAEALAALDRVGLKDRAKHLP-SQLSGG 140
Cdd:PRK10247   83 VSYCAQ----TPTLfgdTVYDNLIFPwQIRNQQPDPAIFLDDLERFALPDTILTKNiAELSGG 141
ABC_DrrA cd03265
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ...
 4-140 2.87e-20

Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213232 [Multi-domain]  Cd Length: 220  Bit Score: 82.42  E-value: 2.87e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   4 LELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDIstlnSRNLTTIRRdKV 83
Cdd:cd03265     1 IEVENLVKKYGDFEAVRGVSFRVRRGEIFGLLGPNGAGKTTTIKMLTTLLKPTSGRATVAGHDV----VREPREVRR-RI 75

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625  84 GLVFQQFHLVPYLTALENIMI-AQYYHSMPDEAE--ALAALDRVGLKDRAKHLPSQLSGG 140
Cdd:cd03265    76 GIVFQDLSVDDELTGWENLYIhARLYGVPGAERRerIDELLDFVGLLEAADRLVKTYSGG 135
CydC TIGR02868
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ...
 4-138 3.13e-20

thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.


Pssm-ID: 274331 [Multi-domain]  Cd Length: 530  Bit Score: 85.10  E-value: 3.13e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   4 LELKDVSMIY-GSVKALQNINLTVERGEWLAIMGPSGSGKTTL-MNIVGCMDKgTSGTVILDGEDISTLNSRNLttirRD 81
Cdd:TIGR02868 335 LELRDLSAGYpGAPPVLDGVSLDLPPGERVAILGPSGSGKSTLlATLAGLLDP-LQGEVTLDGVPVSSLDQDEV----RR 409

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2680999625  82 KVGLVFQQFHLVPyLTALENIMIAQyyhsmPD--EAEALAALDRVGLKDRAKHLPSQLS 138
Cdd:TIGR02868 410 RVSVCAQDAHLFD-TTVRENLRLAR-----PDatDEELWAALERVGLADWLRALPDGLD 462
ABC_BcrA_bacitracin_resist cd03268
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily ...
 4-140 5.68e-20

ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.


Pssm-ID: 213235 [Multi-domain]  Cd Length: 208  Bit Score: 81.49  E-value: 5.68e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   4 LELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDIstlnSRNLTTIRRdkV 83
Cdd:cd03268     1 LKTNDLTKTYGKKRVLDDISLHVKKGEIYGFLGPNGAGKTTTMKIILGLIKPDSGEITFDGKSY----QKNIEALRR--I 74

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2680999625  84 GLVFQQFHLVPYLTALENIMIAQYYHSMPDEaEALAALDRVGLKDRAKHLPSQLSGG 140
Cdd:cd03268    75 GALIEAPGFYPNLTARENLRLLARLLGIRKK-RIDEVLDVVGLKDSAKKKVKGFSLG 130
cbiO PRK13632
cobalt transporter ATP-binding subunit; Provisional
 2-140 1.52e-19

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237452 [Multi-domain]  Cd Length: 271  Bit Score: 81.58  E-value: 1.52e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   2 SLLELKDVSMIYGSVK--ALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEdisTLNSRNLTTIr 79
Cdd:PRK13632    6 VMIKVENVSFSYPNSEnnALKNVSFEINEGEYVAILGHNGSGKSTISKILTGLLKPQSGEIKIDGI---TISKENLKEI- 81

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2680999625  80 RDKVGLVFQ----QFhlvPYLTA-------LENIMIAQyyHSMPDEAEALAalDRVGLKDRAKHLPSQLSGG 140
Cdd:PRK13632   82 RKKIGIIFQnpdnQF---IGATVeddiafgLENKKVPP--KKMKDIIDDLA--KKVGMEDYLDKEPQNLSGG 146
ABC_Iron-Siderophores_B12_Hemin cd03214
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ...
 5-140 2.71e-19

ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.


Pssm-ID: 213181 [Multi-domain]  Cd Length: 180  Bit Score: 79.02  E-value: 2.71e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   5 ELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNSRNlttiRRDKVG 84
Cdd:cd03214     1 EVENLSVGYGGRTVLDDLSLSIEAGEIVGILGPNGAGKSTLLKTLAGLLKPSSGEILLDGKDLASLSPKE----LARKIA 76

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2680999625  85 LVFQqfhlvpyltalenimiaqyyhsmpdeaealaALDRVGLKDRAKHLPSQLSGG 140
Cdd:cd03214    77 YVPQ-------------------------------ALELLGLAHLADRPFNELSGG 101
ABC_Carb_Monos_I cd03216
First domain of the ATP-binding cassette component of monosaccharide transport system; This ...
 4-88 3.05e-19

First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.


Pssm-ID: 213183 [Multi-domain]  Cd Length: 163  Bit Score: 78.24  E-value: 3.05e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   4 LELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNSRNlttIRRDKV 83
Cdd:cd03216     1 LELRGITKRFGGVKALDGVSLSVRRGEVHALLGENGAGKSTLMKILSGLYKPDSGEILVDGKEVSFASPRD---ARRAGI 77


                  ....*
gi 2680999625  84 GLVFQ 88
Cdd:cd03216    78 AMVYQ 82
ABCC_bacteriocin_exporters cd03245
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ...
 4-140 3.52e-19

ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.


Pssm-ID: 213212 [Multi-domain]  Cd Length: 220  Bit Score: 79.56  E-value: 3.52e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   4 LELKDVSMIY--GSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNSRnltTIRRD 81
Cdd:cd03245     3 IEFRNVSFSYpnQEIPALDNVSLTIRAGEKVAIIGRVGSGKSTLLKLLAGLYKPTSGSVLLDGTDIRQLDPA---DLRRN 79

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625  82 kVGLVFQQFHLVpYLTALENIMIAQYYHsmpDEAEALAALDRVGLKDRAKHLP-----------SQLSGG 140
Cdd:cd03245    80 -IGYVPQDVTLF-YGTLRDNITLGAPLA---DDERILRAAELAGVTDFVNKHPngldlqigergRGLSGG 144
ABC_ModC_like cd03299
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely ...
 4-140 4.00e-19

ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely related to ModC. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213266 [Multi-domain]  Cd Length: 235  Bit Score: 79.69  E-value: 4.00e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   4 LELKDVSMIYGSVKaLQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDIStlnsrNLTTIRRDkV 83
Cdd:cd03299     1 LKVENLSKDWKEFK-LKNVSLEVERGDYFVILGPTGSGKSVLLETIAGFIKPDSGKILLNGKDIT-----NLPPEKRD-I 73

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2680999625  84 GLVFQQFHLVPYLTALENI---MIAQYYHSMPDEAEALAALDRVGLkdraKHL----PSQLSGG 140
Cdd:cd03299    74 SYVPQNYALFPHMTVYKNIaygLKKRKVDKKEIERKVLEIAEMLGI----DHLlnrkPETLSGG 133
PRK09984 PRK09984
phosphonate ABC transporter ATP-binding protein;
2-140 5.02e-19

phosphonate ABC transporter ATP-binding protein;


Pssm-ID: 182182 [Multi-domain]  Cd Length: 262  Bit Score: 80.06  E-value: 5.02e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   2 SLLELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMN-----IVGcmDKGTSGTVILDGEDISTlNSRNLT 76
Cdd:PRK09984    3 TIIRVEKLAKTFNQHQALHAVDLNIHHGEMVALLGPSGSGKSTLLRhlsglITG--DKSAGSHIELLGRTVQR-EGRLAR 79

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2680999625  77 TIR--RDKVGLVFQQFHLVPYLTALENIMIAQY-----------YHSMPDEAEALAALDRVGLKDRAKHLPSQLSGG 140
Cdd:PRK09984   80 DIRksRANTGYIFQQFNLVNRLSVLENVLIGALgstpfwrtcfsWFTREQKQRALQALTRVGMVHFAHQRVSTLSGG 156
ModF COG1119
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ...
 1-140 5.08e-19

ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];


Pssm-ID: 440736 [Multi-domain]  Cd Length: 250  Bit Score: 79.74  E-value: 5.08e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   1 MSLLELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGC-MDKGTSGTVILDGEdisTLNSRNLTTIR 79
Cdd:COG1119     1 DPLLELRNVTVRRGGKTILDDISWTVKPGEHWAILGPNGAGKSTLLSLITGdLPPTYGNDVRLFGE---RRGGEDVWELR 77

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625  80 RdKVGLVFQQFH--LVPYLTALENIM------IAQYYHSMP-DEAEALAALDRVGLKDRAKHLPSQLSGG 140
Cdd:COG1119    78 K-RIGLVSPALQlrFPRDETVLDVVLsgffdsIGLYREPTDeQRERARELLELLGLAHLADRPFGTLSQG 146
ABC_MTABC3_MDL1_MDL2 cd03249
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ...
 5-140 7.18e-19

ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.


Pssm-ID: 213216 [Multi-domain]  Cd Length: 238  Bit Score: 79.12  E-value: 7.18e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   5 ELKDVSMIYGS---VKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNSRNLttirRD 81
Cdd:cd03249     2 EFKNVSFRYPSrpdVPILKGLSLTIPPGKTVALVGSSGCGKSTVVSLLERFYDPTSGEILLDGVDIRDLNLRWL----RS 77

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2680999625  82 KVGLVFQQFHLVpYLTALENIMIAQYYHSMPDEAEA--LAALD------------RVGlkDRAkhlpSQLSGG 140
Cdd:cd03249    78 QIGLVSQEPVLF-DGTIAENIRYGKPDATDEEVEEAakKANIHdfimslpdgydtLVG--ERG----SQLSGG 143
ABCC_Protease_Secretion cd03246
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ...
 4-102 9.05e-19

ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.


Pssm-ID: 213213 [Multi-domain]  Cd Length: 173  Bit Score: 77.64  E-value: 9.05e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   4 LELKDVSMIYGSVKA--LQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNSRNLttirRD 81
Cdd:cd03246     1 LEVENVSFRYPGAEPpvLRNVSFSIEPGESLAIIGPSGSGKSTLARLILGLLRPTSGRVRLDGADISQWDPNEL----GD 76

                          90       100
                  ....*....|....*....|.
gi 2680999625  82 KVGLVFQQFHLVPYlTALENI 102
Cdd:cd03246    77 HVGYLPQDDELFSG-SIAENI 96
cbiO PRK13635
energy-coupling factor ABC transporter ATP-binding protein;
2-140 1.15e-18

energy-coupling factor ABC transporter ATP-binding protein;


Pssm-ID: 184195 [Multi-domain]  Cd Length: 279  Bit Score: 79.29  E-value: 1.15e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   2 SLLELKDVSMIY--GSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGediSTLNSRNLTTIR 79
Cdd:PRK13635    4 EIIRVEHISFRYpdAATYALKDVSFSVYEGEWVAIVGHNGSGKSTLAKLLNGLLLPEAGTITVGG---MVLSEETVWDVR 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2680999625  80 RdKVGLVFQ----QF------HLVPYltALENIMIAQyyHSMPDEAEalAALDRVGLKDRAKHLPSQLSGG 140
Cdd:PRK13635   81 R-QVGMVFQnpdnQFvgatvqDDVAF--GLENIGVPR--EEMVERVD--QALRQVGMEDFLNREPHRLSGG 144
ABCC_MsbA cd03251
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ...
 4-140 1.25e-18

ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213218 [Multi-domain]  Cd Length: 234  Bit Score: 78.43  E-value: 1.25e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   4 LELKDVSMIYGS--VKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNSRNLttirRD 81
Cdd:cd03251     1 VEFKNVTFRYPGdgPPVLRDISLDIPAGETVALVGPSGSGKSTLVNLIPRFYDVDSGRILIDGHDVRDYTLASL----RR 76

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625  82 KVGLVFQQFHLVpYLTALENIMiaqYYHSMPDEAEALAALDRVGLKDRAKHLP-----------SQLSGG 140
Cdd:cd03251    77 QIGLVSQDVFLF-NDTVAENIA---YGRPGATREEVEEAARAANAHEFIMELPegydtvigergVKLSGG 142
potG PRK11607
putrescine ABC transporter ATP-binding subunit PotG;
3-140 1.85e-18

putrescine ABC transporter ATP-binding subunit PotG;


Pssm-ID: 183226 [Multi-domain]  Cd Length: 377  Bit Score: 79.88  E-value: 1.85e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   3 LLELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDIStlnsrnLTTIRRDK 82
Cdd:PRK11607   19 LLEIRNLTKSFDGQHAVDDVSLTIYKGEIFALLGASGCGKSTLLRMLAGFEQPTAGQIMLDGVDLS------HVPPYQRP 92

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2680999625  83 VGLVFQQFHLVPYLTALENIMIAQYYHSMP-DEAEALAA--LDRVGLKDRAKHLPSQLSGG 140
Cdd:PRK11607   93 INMMFQSYALFPHMTVEQNIAFGLKQDKLPkAEIASRVNemLGLVHMQEFAKRKPHQLSGG 153
PRK13538 PRK13538
cytochrome c biogenesis heme-transporting ATPase CcmA;
3-140 4.65e-18

cytochrome c biogenesis heme-transporting ATPase CcmA;


Pssm-ID: 184125 [Multi-domain]  Cd Length: 204  Bit Score: 76.38  E-value: 4.65e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   3 LLELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIV-GCMDKgTSGTVILDGEDISTLNS---RNLTTI 78
Cdd:PRK13538    1 MLEARNLACERDERILFSGLSFTLNAGELVQIEGPNGAGKTSLLRILaGLARP-DAGEVLWQGEPIRRQRDeyhQDLLYL 79

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2680999625  79 rrdkvGlvfqqfHLV---PYLTALENIMIAQYYHSMPDEAEALAALDRVGLKDRAkHLP-SQLSGG 140
Cdd:PRK13538   80 -----G------HQPgikTELTALENLRFYQRLHGPGDDEALWEALAQVGLAGFE-DVPvRQLSAG 133
thiQ PRK10771
thiamine ABC transporter ATP-binding protein ThiQ;
23-140 5.54e-18

thiamine ABC transporter ATP-binding protein ThiQ;


Pssm-ID: 182716 [Multi-domain]  Cd Length: 232  Bit Score: 76.54  E-value: 5.54e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625  23 NLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDistlnsRNLTTIRRDKVGLVFQQFHLVPYLTALENI 102
Cdd:PRK10771   19 DLTVERGERVAILGPSGAGKSTLLNLIAGFLTPASGSLTLNGQD------HTTTPPSRRPVSMLFQENNLFSHLTVAQNI 92

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 2680999625 103 MIA-----QYYHSMPDEAEALAalDRVGLKDRAKHLPSQLSGG 140
Cdd:PRK10771   93 GLGlnpglKLNAAQREKLHAIA--RQMGIEDLLARLPGQLSGG 133
PRK10619 PRK10619
histidine ABC transporter ATP-binding protein HisP;
4-140 8.26e-18

histidine ABC transporter ATP-binding protein HisP;


Pssm-ID: 182592 [Multi-domain]  Cd Length: 257  Bit Score: 76.93  E-value: 8.26e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   4 LELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLN---------SRN 74
Cdd:PRK10619    6 LNVIDLHKRYGEHEVLKGVSLQANAGDVISIIGSSGSGKSTFLRCINFLEKPSEGSIVVNGQTINLVRdkdgqlkvaDKN 85

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2680999625  75 LTTIRRDKVGLVFQQFHLVPYLTALENIMIA--QYYHSMPDEAE--ALAALDRVGLKDRAK-HLPSQLSGG 140
Cdd:PRK10619   86 QLRLLRTRLTMVFQHFNLWSHMTVLENVMEApiQVLGLSKQEARerAVKYLAKVGIDERAQgKYPVHLSGG 156
ABC_ModC_molybdenum_transporter cd03297
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ...
 21-140 8.96e-18

ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213264 [Multi-domain]  Cd Length: 214  Bit Score: 75.79  E-value: 8.96e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625  21 NINLTVErGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDI-STLNSRNLTTIRRdKVGLVFQQFHLVPYLTAL 99
Cdd:cd03297    16 KIDFDLN-EEVTGIFGASGAGKSTLLRCIAGLEKPDGGTIVLNGTVLfDSRKKINLPPQQR-KIGLVFQQYALFPHLNVR 93

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 2680999625 100 ENIMIAQYYHS-MPDEAEALAALDRVGLKDRAKHLPSQLSGG 140
Cdd:cd03297    94 ENLAFGLKRKRnREDRISVDELLDLLGLDHLLNRYPAQLSGG 135
ABCG_EPDR cd03213
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ...
 19-105 1.00e-17

Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.


Pssm-ID: 213180 [Multi-domain]  Cd Length: 194  Bit Score: 75.28  E-value: 1.00e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625  19 LQNINLTVERGEWLAIMGPSGSGKTTLMNIVGC--MDKGTSGTVILDGEDISTLNSRNLttirrdkVGLVFQQFHLVPYL 96
Cdd:cd03213    25 LKNVSGKAKPGELTAIMGPSGAGKSTLLNALAGrrTGLGVSGEVLINGRPLDKRSFRKI-------IGYVPQDDILHPTL 97


                  ....*....
gi 2680999625  97 TALENIMIA 105
Cdd:cd03213    98 TVRETLMFA 106
ABCC_Glucan_exporter_like cd03254
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ...
 5-134 1.42e-17

ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213221 [Multi-domain]  Cd Length: 229  Bit Score: 75.72  E-value: 1.42e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   5 ELKDVSMIYGSVK-ALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNSRNLttirRDKV 83
Cdd:cd03254     4 EFENVNFSYDEKKpVLKDINFSIKPGETVAIVGPTGAGKTTLINLLMRFYDPQKGQILIDGIDIRDISRKSL----RSMI 79

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2680999625  84 GLVFQQFHLVPYlTALENImiaQYYHSMPDEAEALAALDRVGLKDRAKHLP 134
Cdd:cd03254    80 GVVLQDTFLFSG-TIMENI---RLGRPNATDEEVIEAAKEAGAHDFIMKLP 126
YhaQ COG4152
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
 4-140 1.65e-17

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 443322 [Multi-domain]  Cd Length: 298  Bit Score: 76.30  E-value: 1.65e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   4 LELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLM-NIVGCMDKgTSGTVILDGEDISTLNsrnlttirRDK 82
Cdd:COG4152     2 LELKGLTKRFGDKTAVDDVSFTVPKGEIFGLLGPNGAGKTTTIrIILGILAP-DSGEVLWDGEPLDPED--------RRR 72

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2680999625  83 VGL------------VFQQfhLVpYLTALenimiaqyyHSMPdEAEALAA----LDRVGLKDRAKHLPSQLSGG 140
Cdd:COG4152    73 IGYlpeerglypkmkVGEQ--LV-YLARL---------KGLS-KAEAKRRadewLERLGLGDRANKKVEELSKG 133
CydD TIGR02857
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ...
 4-140 1.93e-17

thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD


Pssm-ID: 274323 [Multi-domain]  Cd Length: 529  Bit Score: 77.33  E-value: 1.93e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   4 LELKDVSMIY-GSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNSRNLttirRDK 82
Cdd:TIGR02857 322 LEFSGVSVAYpGRRPALRPVSFTVPPGERVALVGPSGAGKSTLLNLLLGFVDPTEGSIAVNGVPLADADADSW----RDQ 397

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2680999625  83 VGLVFQQFHLVPYlTALENIMIAQYYHSmpdEAEALAALDRVGLKDRAKHLP-----------SQLSGG 140
Cdd:TIGR02857 398 IAWVPQHPFLFAG-TIAENIRLARPDAS---DAEIREALERAGLDEFVAALPqgldtpigeggAGLSGG 462
cbiO PRK13641
energy-coupling factor transporter ATPase;
1-140 2.19e-17

energy-coupling factor transporter ATPase;


Pssm-ID: 237456 [Multi-domain]  Cd Length: 287  Bit Score: 76.02  E-value: 2.19e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   1 MSLlELKDVSMIYG-----SVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDI-STLNSRN 74
Cdd:PRK13641    1 MSI-KFENVDYIYSpgtpmEKKGLDNISFELEEGSFVALVGHTGSGKSTLMQHFNALLKPSSGTITIAGYHItPETGNKN 79

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2680999625  75 LTTIRRdKVGLVFqQFHLVPYL--TALENIMIA-QYYHSMPDEAE--ALAALDRVGLK-DRAKHLPSQLSGG 140
Cdd:PRK13641   80 LKKLRK-KVSLVF-QFPEAQLFenTVLKDVEFGpKNFGFSEDEAKekALKWLKKVGLSeDLISKSPFELSGG 149
YejF COG4172
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ...
 3-140 2.56e-17

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443332 [Multi-domain]  Cd Length: 533  Bit Score: 77.03  E-value: 2.56e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   3 LLELKDVSMIY-----------GSVKALQNINLTVERGEWLAIMGPSGSGKTTL-MNIVGCMDkgTSGTVILDGEDISTL 70
Cdd:COG4172   275 LLEARDLKVWFpikrglfrrtvGHVKAVDGVSLTLRRGETLGLVGESGSGKSTLgLALLRLIP--SEGEIRFDGQDLDGL 352

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625  71 NSRNLTTIRRDkVGLVFQQfhlvPY------LTALENI---MIAQYYHSMPDEAEAL--AALDRVGLKDRAKH-LPSQLS 138
Cdd:COG4172   353 SRRALRPLRRR-MQVVFQD----PFgslsprMTVGQIIaegLRVHGPGLSAAERRARvaEALEEVGLDPAARHrYPHEFS 427


                  ..
gi 2680999625 139 GG 140
Cdd:COG4172   428 GG 429
cbiO PRK13637
energy-coupling factor transporter ATPase;
1-88 2.64e-17

energy-coupling factor transporter ATPase;


Pssm-ID: 237455 [Multi-domain]  Cd Length: 287  Bit Score: 75.85  E-value: 2.64e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   1 MSLlELKDVSMIY--GS---VKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDIsTLNSRNL 75
Cdd:PRK13637    1 MSI-KIENLTHIYmeGTpfeKKALDNVNIEIEDGEFVGLIGHTGSGKSTLIQHLNGLLKPTSGKIIIDGVDI-TDKKVKL 78

                          90
                  ....*....|...
gi 2680999625  76 TTIRRdKVGLVFQ 88
Cdd:PRK13637   79 SDIRK-KVGLVFQ 90
araG PRK11288
L-arabinose ABC transporter ATP-binding protein AraG;
1-127 3.72e-17

L-arabinose ABC transporter ATP-binding protein AraG;


Pssm-ID: 183077 [Multi-domain]  Cd Length: 501  Bit Score: 76.49  E-value: 3.72e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   1 MSLLELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEdisTLNSRNLTTIRR 80
Cdd:PRK11288    2 SPYLSFDGIGKTFPGVKALDDISFDCRAGQVHALMGENGAGKSTLLKILSGNYQPDAGSILIDGQ---EMRFASTTAALA 78

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2680999625  81 DKVGLVFQQFHLVPYLTALENIMIAQYYHS--MPDE----AEALAALDRVGLK 127
Cdd:PRK11288   79 AGVAIIYQELHLVPEMTVAENLYLGQLPHKggIVNRrllnYEAREQLEHLGVD 131
ABC_FeS_Assembly cd03217
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of ...
 4-88 4.96e-17

ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.


Pssm-ID: 213184 [Multi-domain]  Cd Length: 200  Bit Score: 73.72  E-value: 4.96e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   4 LELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMN-IVGCMD-KGTSGTVILDGEDIStlnsrNLTTIRRD 81
Cdd:cd03217     1 LEIKDLHVSVGGKEILKGVNLTIKKGEVHALMGPNGSGKSTLAKtIMGHPKyEVTEGEILFKGEDIT-----DLPPEERA 75


                  ....*....
gi 2680999625  82 KVG--LVFQ 88
Cdd:cd03217    76 RLGifLAFQ 84
PRK13549 PRK13549
xylose transporter ATP-binding subunit; Provisional
 3-102 1.05e-16

xylose transporter ATP-binding subunit; Provisional


Pssm-ID: 184134 [Multi-domain]  Cd Length: 506  Bit Score: 75.35  E-value: 1.05e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   3 LLELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIV-GCMDKGT-SGTVILDGEdisTLNSRNLTTIRR 80
Cdd:PRK13549    5 LLEMKNITKTFGGVKALDNVSLKVRAGEIVSLCGENGAGKSTLMKVLsGVYPHGTyEGEIIFEGE---ELQASNIRDTER 81

                          90       100
                  ....*....|....*....|..
gi 2680999625  81 DKVGLVFQQFHLVPYLTALENI 102
Cdd:PRK13549   82 AGIAIIHQELALVKELSVLENI 103
ssuB PRK11247
aliphatic sulfonates transport ATP-binding subunit; Provisional
 4-140 1.07e-16

aliphatic sulfonates transport ATP-binding subunit; Provisional


Pssm-ID: 183055 [Multi-domain]  Cd Length: 257  Bit Score: 73.56  E-value: 1.07e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   4 LELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTvILDGedistlnSRNLTTIRRDkV 83
Cdd:PRK11247   13 LLLNAVSKRYGERTVLNQLDLHIPAGQFVAVVGRSGCGKSTLLRLLAGLETPSAGE-LLAG-------TAPLAEARED-T 83

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2680999625  84 GLVFQQFHLVPYLTALENIMIAQYYHSMPDeaeALAALDRVGLKDRAKHLPSQLSGG 140
Cdd:PRK11247   84 RLMFQDARLLPWKKVIDNVGLGLKGQWRDA---ALQALAAVGLADRANEWPAALSGG 137
GguA NF040905
sugar ABC transporter ATP-binding protein;
3-128 1.39e-16

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 74.83  E-value: 1.39e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   3 LLELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIV-GCMDKGT-SGTVILDGEdistlnSRNLTTIR- 79
Cdd:NF040905    1 ILEMRGITKTFPGVKALDDVNLSVREGEIHALCGENGAGKSTLMKVLsGVYPHGSyEGEILFDGE------VCRFKDIRd 74

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2680999625  80 RDKVGLVF--QQFHLVPYLTALENIM----IAQY----YHSMPDEAEALaaLDRVGLKD 128
Cdd:NF040905   75 SEALGIVIihQELALIPYLSIAENIFlgneRAKRgvidWNETNRRAREL--LAKVGLDE 131
ABCG_White cd03234
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ...
 15-140 1.46e-16

White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.


Pssm-ID: 213201 [Multi-domain]  Cd Length: 226  Bit Score: 72.69  E-value: 1.46e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625  15 SVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKG---TSGTVILDGEDistlNSRNLTtirRDKVGLVFQQFH 91
Cdd:cd03234    19 YARILNDVSLHVESGQVMAILGSSGSGKTTLLDAISGRVEGggtTSGQILFNGQP----RKPDQF---QKCVAYVRQDDI 91

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2680999625  92 LVPYLTALENI----MIAQYYHS---MPDEAEALAALDRVGLKDRAKHLPSQLSGG 140
Cdd:cd03234    92 LLPGLTVRETLtytaILRLPRKSsdaIRKKRVEDVLLRDLALTRIGGNLVKGISGG 147
ABC_putative_ATPase cd03269
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ...
 4-140 1.99e-16

ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213236 [Multi-domain]  Cd Length: 210  Bit Score: 72.31  E-value: 1.99e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   4 LELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNsrnlttirRDKV 83
Cdd:cd03269     1 LEVENVTKRFGRVTALDDISFSVEKGEIFGLLGPNGAGKTTTIRMILGIILPDSGEVLFDGKPLDIAA--------RNRI 72

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625  84 GLVFQQFHLVPYLTALENIM-IAQYYHSMPDEA--EALAALDRVGLKDRAKHLPSQLSGG 140
Cdd:cd03269    73 GYLPEERGLYPKMKVIDQLVyLAQLKGLKKEEArrRIDEWLERLELSEYANKRVEELSKG 132
cbiO PRK13648
cobalt transporter ATP-binding subunit; Provisional
 2-140 5.00e-16

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184207 [Multi-domain]  Cd Length: 269  Bit Score: 72.09  E-value: 5.00e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   2 SLLELKDVSMIYGSVKA--LQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDIstlNSRNLTTIR 79
Cdd:PRK13648    6 SIIVFKNVSFQYQSDASftLKDVSFNIPKGQWTSIVGHNGSGKSTIAKLMIGIEKVKSGEIFYNNQAI---TDDNFEKLR 82

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2680999625  80 RDkVGLVFQ----QF--HLVPYLTA--LENIMIAqyYHSMPDEAEalAALDRVGLKDRAKHLPSQLSGG 140
Cdd:PRK13648   83 KH-IGIVFQnpdnQFvgSIVKYDVAfgLENHAVP--YDEMHRRVS--EALKQVDMLERADYEPNALSGG 146
cbiO PRK13652
cobalt transporter ATP-binding subunit; Provisional
 1-140 1.13e-15

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 172200 [Multi-domain]  Cd Length: 277  Bit Score: 71.37  E-value: 1.13e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   1 MSLLELKDVSMIY-GSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNSRNLttir 79
Cdd:PRK13652    1 MHLIETRDLCYSYsGSKEALNNINFIAPRNSRIAVIGPNGAGKSTLFRHFNGILKPTSGSVLIRGEPITKENIREV---- 76

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2680999625  80 RDKVGLVFQQFHLVPYLTALENiMIAQYYHSMPDEAEALA-----ALDRVGLKDRAKHLPSQLSGG 140
Cdd:PRK13652   77 RKFVGLVFQNPDDQIFSPTVEQ-DIAFGPINLGLDEETVAhrvssALHMLGLEELRDRVPHHLSGG 141
xylG TIGR02633
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ...
 3-104 1.41e-15

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 131681 [Multi-domain]  Cd Length: 500  Bit Score: 72.16  E-value: 1.41e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   3 LLELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIV-GCMDKGT-SGTVILDGEDistLNSRNLTTIRR 80
Cdd:TIGR02633   1 LLEMKGIVKTFGGVKALDGIDLEVRPGECVGLCGENGAGKSTLMKILsGVYPHGTwDGEIYWSGSP---LKASNIRDTER 77

                          90       100
                  ....*....|....*....|....
gi 2680999625  81 DKVGLVFQQFHLVPYLTALENIMI 104
Cdd:TIGR02633  78 AGIVIIHQELTLVPELSVAENIFL 101
ABC_YhbG cd03218
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ...
 4-140 1.46e-15

ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.


Pssm-ID: 213185 [Multi-domain]  Cd Length: 232  Bit Score: 70.26  E-value: 1.46e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   4 LELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNSRnlttiRRDKV 83
Cdd:cd03218     1 LRAENLSKRYGKRKVVNGVSLSVKQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGKILLDGQDITKLPMH-----KRARL 75

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2680999625  84 GLVF--QQFHLVPYLTALENIMIAQYYHSMPDE-----AEALaaLDRVGLKDRAKHLPSQLSGG 140
Cdd:cd03218    76 GIGYlpQEASIFRKLTVEENILAVLEIRGLSKKereekLEEL--LEEFHITHLRKSKASSLSGG 137
PRK09700 PRK09700
D-allose ABC transporter ATP-binding protein AlsA;
3-127 1.87e-15

D-allose ABC transporter ATP-binding protein AlsA;


Pssm-ID: 182036 [Multi-domain]  Cd Length: 510  Bit Score: 71.74  E-value: 1.87e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   3 LLELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNSRNLTTIrrdK 82
Cdd:PRK09700    5 YISMAGIGKSFGPVHALKSVNLTVYPGEIHALLGENGAGKSTLMKVLSGIHEPTKGTITINNINYNKLDHKLAAQL---G 81

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2680999625  83 VGLVFQQFHLVPYLTALENIMIAQY------------YHSMPDEAEALaaLDRVGLK 127
Cdd:PRK09700   82 IGIIYQELSVIDELTVLENLYIGRHltkkvcgvniidWREMRVRAAMM--LLRVGLK 136
nikE PRK10419
nickel ABC transporter ATP-binding protein NikE;
1-140 2.38e-15

nickel ABC transporter ATP-binding protein NikE;


Pssm-ID: 236689 [Multi-domain]  Cd Length: 268  Bit Score: 70.10  E-value: 2.38e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   1 MSLLELKDVSMIYGSV---------KALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLN 71
Cdd:PRK10419    1 MTLLNVSGLSHHYAHGglsgkhqhqTVLNNVSLSLKSGETVALLGRSGCGKSTLARLLVGLESPSQGNVSWRGEPLAKLN 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2680999625  72 SRNLTTIRRDkVGLVFQQ-FHLV-PYLTALENIMIAQYYHSMPDEAE----ALAALDRVGLKDR-AKHLPSQLSGG 140
Cdd:PRK10419   81 RAQRKAFRRD-IQMVFQDsISAVnPRKTVREIIREPLRHLLSLDKAErlarASEMLRAVDLDDSvLDKRPPQLSGG 155
PRK14247 PRK14247
phosphate ABC transporter ATP-binding protein; Provisional
 1-140 3.82e-15

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172735 [Multi-domain]  Cd Length: 250  Bit Score: 69.56  E-value: 3.82e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   1 MSLLELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCM-----DKGTSGTVILDGEDISTLnsrNL 75
Cdd:PRK14247    1 MNKIEIRDLKVSFGQVEVLDGVNLEIPDNTITALMGPSGSGKSTLLRVFNRLielypEARVSGEVYLDGQDIFKM---DV 77

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2680999625  76 TTIRRdKVGLVFQQFHLVPYLTALENIMIAQYYHSMPDEAEALA-----ALDRVGL----KDRAKHLPSQLSGG 140
Cdd:PRK14247   78 IELRR-RVQMVFQIPNPIPNLSIFENVALGLKLNRLVKSKKELQervrwALEKAQLwdevKDRLDAPAGKLSGG 150
ccmA TIGR01189
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein ...
 4-140 4.82e-15

heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein encoded by ccmA in bacteria. An exception is, an arabidopsis protein. Quite likely this is encoded by an organelle. Bacterial c-type cytocromes are located on the periplasmic side of the cytoplasmic membrane. Several gene products encoded in a locus designated as 'ccm' are implicated in the transport and assembly of the functional cytochrome C. This cluster includes genes: ccmA;B;C;D;E;F;G and H. The posttranslational pathway includes the transport of heme moiety, the secretion of the apoprotein and the covalent attachment of the heme with the apoprotein. The proteins ccmA and B represent an ABC transporter; ccmC and D participate in heme transfer to ccmE, which function as a periplasmic heme chaperone. The presence of ccmF, G and H is suggested to be obligatory for the final functional assembly of cytochrome c. [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Other]


Pssm-ID: 273491 [Multi-domain]  Cd Length: 198  Bit Score: 68.15  E-value: 4.82e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   4 LELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTlnsrnLTTIRRDKV 83
Cdd:TIGR01189   1 LAARNLACSRGERMLFEGLSFTLNAGEALQVTGPNGIGKTTLLRILAGLLRPDSGEVRWNGTPLAE-----QRDEPHENI 75

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625  84 GLVFQQFHLVPYLTALENImiaQYYHSMPDEAE--ALAALDRVGLKDRAkHLP-SQLSGG 140
Cdd:TIGR01189  76 LYLGHLPGLKPELSALENL---HFWAAIHGGAQrtIEDALAAVGLTGFE-DLPaAQLSAG 131
oppD PRK09473
oligopeptide transporter ATP-binding component; Provisional
 1-140 5.45e-15

oligopeptide transporter ATP-binding component; Provisional


Pssm-ID: 181888 [Multi-domain]  Cd Length: 330  Bit Score: 69.75  E-value: 5.45e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   1 MSLLELKDVSMIY----GSVKALQNINLTVERGEWLAIMGPSGSGKT-TLMNIVGCMDKG--TSGTVILDGEDISTLNSR 73
Cdd:PRK09473   10 DALLDVKDLRVTFstpdGDVTAVNDLNFSLRAGETLGIVGESGSGKSqTAFALMGLLAANgrIGGSATFNGREILNLPEK 89

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2680999625  74 NLTTIRRDKVGLVFQQ--FHLVPYLTALENIMIAQYYHSMPDEAEALAA----LDRVGL---KDRAKHLPSQLSGG 140
Cdd:PRK09473   90 ELNKLRAEQISMIFQDpmTSLNPYMRVGEQLMEVLMLHKGMSKAEAFEEsvrmLDAVKMpeaRKRMKMYPHEFSGG 165
ugpC PRK11650
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;
1-140 6.15e-15

sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;


Pssm-ID: 236947 [Multi-domain]  Cd Length: 356  Bit Score: 69.87  E-value: 6.15e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   1 MSLLELKDVSMIY-GSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNSRNlttir 79
Cdd:PRK11650    1 MAGLKLQAVRKSYdGKTQVIKGIDLDVADGEFIVLVGPSGCGKSTLLRMVAGLERITSGEIWIGGRVVNELEPAD----- 75

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2680999625  80 RDkVGLVFQQFHLVPYLTALENIMIAQYYHSMPDE------AEALAALDRVGLKDRAkhlPSQLSGG 140
Cdd:PRK11650   76 RD-IAMVFQNYALYPHMSVRENMAYGLKIRGMPKAeieervAEAARILELEPLLDRK---PRELSGG 138
ModC COG4148
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and ...
 21-140 7.62e-15

ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, ATPase component ModC is part of the Pathway/BioSystem: Molybdopterin biosynthesis


Pssm-ID: 443319 [Multi-domain]  Cd Length: 358  Bit Score: 69.36  E-value: 7.62e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625  21 NINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDI-STLNSRNLTTIRRdKVGLVFQQFHLVPYLTAL 99
Cdd:COG4148    17 DVDFTLPGRGVTALFGPSGSGKTTLLRAIAGLERPDSGRIRLGGEVLqDSARGIFLPPHRR-RIGYVFQEARLFPHLSVR 95

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 2680999625 100 ENImiaQYYHSMPDEAEALAALDRV----GLKDRAKHLPSQLSGG 140
Cdd:COG4148    96 GNL---LYGRKRAPRAERRISFDEVvellGIGHLLDRRPATLSGG 137
SufC COG0396
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, ...
 4-89 8.76e-15

Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440165 [Multi-domain]  Cd Length: 245  Bit Score: 68.17  E-value: 8.76e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   4 LELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVgcMDKG----TSGTVILDGEDIStlnsrNLTTIR 79
Cdd:COG0396     1 LEIKNLHVSVEGKEILKGVNLTIKPGEVHAIMGPNGSGKSTLAKVL--MGHPkyevTSGSILLDGEDIL-----ELSPDE 73

                          90
                  ....*....|..
gi 2680999625  80 RDKVG--LVFQQ 89
Cdd:COG0396    74 RARAGifLAFQY 85
cbiO PRK13639
cobalt transporter ATP-binding subunit; Provisional
 3-140 1.20e-14

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184199 [Multi-domain]  Cd Length: 275  Bit Score: 68.57  E-value: 1.20e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   3 LLELKDVSMIY--GSVkALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDIStLNSRNLTTIRR 80
Cdd:PRK13639    1 ILETRDLKYSYpdGTE-ALKGINFKAEKGEMVALLGPNGAGKSTLFLHFNGILKPTSGEVLIKGEPIK-YDKKSLLEVRK 78

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2680999625  81 dKVGLVFQ----QFhLVPylTALENIMIAQYYHSMP-DEAE--ALAALDRVGLKDRAKHLPSQLSGG 140
Cdd:PRK13639   79 -TVGIVFQnpddQL-FAP--TVEEDVAFGPLNLGLSkEEVEkrVKEALKAVGMEGFENKPPHHLSGG 141
btuD PRK09536
corrinoid ABC transporter ATPase; Reviewed
 1-75 1.38e-14

corrinoid ABC transporter ATPase; Reviewed


Pssm-ID: 236554 [Multi-domain]  Cd Length: 402  Bit Score: 69.10  E-value: 1.38e-14
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2680999625   1 MSLLELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNSRNL 75
Cdd:PRK09536    1 MPMIDVSDLSVEFGDTTVLDGVDLSVREGSLVGLVGPNGAGKTTLLRAINGTLTPTAGTVLVAGDDVEALSARAA 75
PRK14267 PRK14267
phosphate ABC transporter ATP-binding protein; Provisional
 4-140 1.65e-14

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 184596 [Multi-domain]  Cd Length: 253  Bit Score: 67.94  E-value: 1.65e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   4 LELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCM-----DKGTSGTVILDGEDIStlnSRNLTTI 78
Cdd:PRK14267    5 IETVNLRVYYGSNHVIKGVDLKIPQNGVFALMGPSGCGKSTLLRTFNRLlelneEARVEGEVRLFGRNIY---SPDVDPI 81

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2680999625  79 R-RDKVGLVFQQFHLVPYLTALENIMIAQYYHSMPDEAEALA-----ALDRVGL----KDRAKHLPSQLSGG 140
Cdd:PRK14267   82 EvRREVGMVFQYPNPFPHLTIYDNVAIGVKLNGLVKSKKELDervewALKKAALwdevKDRLNDYPSNLSGG 153
PRK13633 PRK13633
energy-coupling factor transporter ATPase;
3-140 1.96e-14

energy-coupling factor transporter ATPase;


Pssm-ID: 237453 [Multi-domain]  Cd Length: 280  Bit Score: 67.81  E-value: 1.96e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   3 LLELKDVSMIYGSVK------ALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDisTLNSRNLT 76
Cdd:PRK13633    4 MIKCKNVSYKYESNEesteklALDDVNLEVKKGEFLVILGRNGSGKSTIAKHMNALLIPSEGKVYVDGLD--TSDEENLW 81

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2680999625  77 TIRRdKVGLVFQQ--FHLVPYLT------ALENIMIAqyyhsmPDEAEALA--ALDRVGLKDRAKHLPSQLSGG 140
Cdd:PRK13633   82 DIRN-KAGMVFQNpdNQIVATIVeedvafGPENLGIP------PEEIRERVdeSLKKVGMYEYRRHAPHLLSGG 148
PhnL COG4778
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion ...
 3-140 2.09e-14

Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion transport and metabolism];


Pssm-ID: 443809 [Multi-domain]  Cd Length: 229  Bit Score: 67.07  E-value: 2.09e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   3 LLELKDVSMIY-----GSVK--ALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGE----DISTLN 71
Cdd:COG4778     4 LLEVENLSKTFtlhlqGGKRlpVLDGVSFSVAAGECVALTGPSGAGKSTLLKCIYGNYLPDSGSILVRHDggwvDLAQAS 83

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2680999625  72 SRNLTTIRRDKVGLVFQQFHLVPYLTALENIM---IAQYYhsMPDEAEALAA--LDRVGLKDRAKHL-PSQLSGG 140
Cdd:COG4778    84 PREILALRRRTIGYVSQFLRVIPRVSALDVVAeplLERGV--DREEARARARelLARLNLPERLWDLpPATFSGG 156
ABCC_MRP_domain2 cd03244
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C ...
 4-137 2.23e-14

ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resistance lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213211 [Multi-domain]  Cd Length: 221  Bit Score: 66.75  E-value: 2.23e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   4 LELKDVSMIY--GSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNSRNLttirRD 81
Cdd:cd03244     3 IEFKNVSLRYrpNLPPVLKNISFSIKPGEKVGIVGRTGSGKSSLLLALFRLVELSSGSILIDGVDISKIGLHDL----RS 78

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2680999625  82 KVGLVFQQfhlvPYL---TALENIMIAQYYhsmpDEAEALAALDRVGLKDRAKHLPSQL 137
Cdd:cd03244    79 RISIIPQD----PVLfsgTIRSNLDPFGEY----SDEELWQALERVGLKEFVESLPGGL 129
TagH COG1134
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ...
 13-104 2.26e-14

ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440749 [Multi-domain]  Cd Length: 245  Bit Score: 67.41  E-value: 2.26e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625  13 YGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEdISTLNSrnlttirrdkVGLVFQqfhl 92
Cdd:COG1134    36 REEFWALKDVSFEVERGESVGIIGRNGAGKSTLLKLIAGILEPTSGRVEVNGR-VSALLE----------LGAGFH---- 100

                          90
                  ....*....|..
gi 2680999625  93 vPYLTALENIMI 104
Cdd:COG1134   101 -PELTGRENIYL 111
cbiO PRK13650
energy-coupling factor transporter ATPase;
1-140 3.09e-14

energy-coupling factor transporter ATPase;


Pssm-ID: 184209 [Multi-domain]  Cd Length: 279  Bit Score: 67.45  E-value: 3.09e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   1 MSLLELKDVSMIYGSVK---ALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNSRNLtt 77
Cdd:PRK13650    2 SNIIEVKNLTFKYKEDQekyTLNDVSFHVKQGEWLSIIGHNGSGKSTTVRLIDGLLEAESGQIIIDGDLLTEENVWDI-- 79

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2680999625  78 irRDKVGLVFQ----QF--HLVPYLTA--LENIMIAqyYHSMPDEAEalAALDRVGLKDRAKHLPSQLSGG 140
Cdd:PRK13650   80 --RHKIGMVFQnpdnQFvgATVEDDVAfgLENKGIP--HEEMKERVN--EALELVGMQDFKEREPARLSGG 144
met_CoM_red_A2 TIGR03269
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ...
 4-140 7.77e-14

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]


Pssm-ID: 132313 [Multi-domain]  Cd Length: 520  Bit Score: 67.13  E-value: 7.77e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   4 LELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMD--KGTSGTVI-------------------- 61
Cdd:TIGR03269   1 IEVKNLTKKFDGKEVLKNISFTIEEGEVLGILGRSGAGKSVLMHVLRGMDqyEPTSGRIIyhvalcekcgyverpskvge 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625  62 --------LDGEDISTLN-SRNLTTIRRDKVGLVFQQ-FHLVPYLTALENIMiaqyyHSMPD---EAE-----ALAALDR 123
Cdd:TIGR03269  81 pcpvcggtLEPEEVDFWNlSDKLRRRIRKRIAIMLQRtFALYGDDTVLDNVL-----EALEEigyEGKeavgrAVDLIEM 155

                         170
                  ....*....|....*..
gi 2680999625 124 VGLKDRAKHLPSQLSGG 140
Cdd:TIGR03269 156 VQLSHRITHIARDLSGG 172
Uup COG0488
ATPase components of ABC transporters with duplicated ATPase domains [General function ...
 6-140 1.34e-13

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];


Pssm-ID: 440254 [Multi-domain]  Cd Length: 520  Bit Score: 66.24  E-value: 1.34e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   6 LKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDgedistlnsrnlttiRRDKVGL 85
Cdd:COG0488     1 LENLSKSFGGRPLLDDVSLSINPGDRIGLVGRNGAGKSTLLKILAGELEPDSGEVSIP---------------KGLRIGY 65

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625  86 VFQQFHLVPYLTALENIM---------IAQY---YHSMPD-----------------------EAEALAALDRVGLKDRA 130
Cdd:COG0488    66 LPQEPPLDDDLTVLDTVLdgdaelralEAELeelEAKLAEpdedlerlaelqeefealggweaEARAEEILSGLGFPEED 145

                         170
                  ....*....|.
gi 2680999625 131 KHLP-SQLSGG 140
Cdd:COG0488   146 LDRPvSELSGG 156
PRK13657 PRK13657
glucan ABC transporter ATP-binding protein/ permease;
3-140 1.72e-13

glucan ABC transporter ATP-binding protein/ permease;


Pssm-ID: 184214 [Multi-domain]  Cd Length: 588  Bit Score: 66.14  E-value: 1.72e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   3 LLELKDVSMIY-GSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNSRNLttirRD 81
Cdd:PRK13657  334 AVEFDDVSFSYdNSRQGVEDVSFEAKPGQTVAIVGPTGAGKSTLINLLQRVFDPQSGRILIDGTDIRTVTRASL----RR 409

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625  82 KVGLVFQQfhlvPYL---TALENIMIAQYYHS---MPDEAEALAALDRV-----GLKDRAKHLPSQLSGG 140
Cdd:PRK13657  410 NIAVVFQD----AGLfnrSIEDNIRVGRPDATdeeMRAAAERAQAHDFIerkpdGYDTVVGERGRQLSGG 475
cbiO PRK13649
energy-coupling factor transporter ATPase;
4-140 1.78e-13

energy-coupling factor transporter ATPase;


Pssm-ID: 184208 [Multi-domain]  Cd Length: 280  Bit Score: 65.15  E-value: 1.78e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   4 LELKDVSMIYGS-----VKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDI-STLNSRNLTT 77
Cdd:PRK13649    3 INLQNVSYTYQAgtpfeGRALFDVNLTIEDGSYTAFIGHTGSGKSTIMQLLNGLHVPTQGSVRVDDTLItSTSKNKDIKQ 82

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2680999625  78 IRRdKVGLVFQ--QFHLVPYlTALENIMIA-QYYHSMPDEAEALA--ALDRVGL-KDRAKHLPSQLSGG 140
Cdd:PRK13649   83 IRK-KVGLVFQfpESQLFEE-TVLKDVAFGpQNFGVSQEEAEALAreKLALVGIsESLFEKNPFELSGG 149
met_CoM_red_A2 TIGR03269
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ...
 3-140 1.82e-13

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]


Pssm-ID: 132313 [Multi-domain]  Cd Length: 520  Bit Score: 65.98  E-value: 1.82e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   3 LLELKDVSMIY-----GSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTV-ILDGEDISTLNSRNLT 76
Cdd:TIGR03269 279 IIKVRNVSKRYisvdrGVVKAVDNVSLEVKEGEIFGIVGTSGAGKTTLSKIIAGVLEPTSGEVnVRVGDEWVDMTKPGPD 358

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2680999625  77 TIRRDK--VGLVFQQFHLVPYLTALENIMIAQYYhSMPDE---AEALAALDRVGL-KDRAKH----LPSQLSGG 140
Cdd:TIGR03269 359 GRGRAKryIGILHQEYDLYPHRTVLDNLTEAIGL-ELPDElarMKAVITLKMVGFdEEKAEEildkYPDELSEG 431
PRK11000 PRK11000
maltose/maltodextrin ABC transporter ATP-binding protein MalK;
1-102 2.47e-13

maltose/maltodextrin ABC transporter ATP-binding protein MalK;


Pssm-ID: 182893 [Multi-domain]  Cd Length: 369  Bit Score: 65.44  E-value: 2.47e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   1 MSLLELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTL--NSRNltti 78
Cdd:PRK11000    1 MASVTLRNVTKAYGDVVISKDINLDIHEGEFVVFVGPSGCGKSTLLRMIAGLEDITSGDLFIGEKRMNDVppAERG---- 76

                          90       100
                  ....*....|....*....|....
gi 2680999625  79 rrdkVGLVFQQFHLVPYLTALENI 102
Cdd:PRK11000   77 ----VGMVFQSYALYPHLSVAENM 96
cbiO PRK13634
cobalt transporter ATP-binding subunit; Provisional
 17-140 2.48e-13

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237454 [Multi-domain]  Cd Length: 290  Bit Score: 65.04  E-value: 2.48e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625  17 KALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILdGEDISTLNSRN--LTTIRRdKVGLVFqQF--HL 92
Cdd:PRK13634   21 RALYDVNVSIPSGSYVAIIGHTGSGKSTLLQHLNGLLQPTSGTVTI-GERVITAGKKNkkLKPLRK-KVGIVF-QFpeHQ 97

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2680999625  93 VPYLTALENIMIAQYYHSMP-DEAEALA--ALDRVGL-KDRAKHLPSQLSGG 140
Cdd:PRK13634   98 LFEETVEKDICFGPMNFGVSeEDAKQKAreMIELVGLpEELLARSPFELSGG 149
PRK14239 PRK14239
phosphate transporter ATP-binding protein; Provisional
 3-103 2.90e-13

phosphate transporter ATP-binding protein; Provisional


Pssm-ID: 184585 [Multi-domain]  Cd Length: 252  Bit Score: 64.41  E-value: 2.90e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   3 LLELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDK-----GTSGTVILDGEDIStlnSRNLTT 77
Cdd:PRK14239    5 ILQVSDLSVYYNKKKALNSVSLDFYPNEITALIGPSGSGKSTLLRSINRMNDlnpevTITGSIVYNGHNIY---SPRTDT 81

                          90       100
                  ....*....|....*....|....*..
gi 2680999625  78 IR-RDKVGLVFQQFHLVPyLTALENIM 103
Cdd:PRK14239   82 VDlRKEIGMVFQQPNPFP-MSIYENVV 107
hmuV PRK13548
hemin importer ATP-binding subunit; Provisional
 3-140 4.24e-13

hemin importer ATP-binding subunit; Provisional


Pssm-ID: 237422 [Multi-domain]  Cd Length: 258  Bit Score: 64.02  E-value: 4.24e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   3 LLELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVgCMD-KGTSGTVILDGEDISTLNSRNLTTIRrd 81
Cdd:PRK13548    2 MLEARNLSVRLGGRTLLDDVSLTLRPGEVVAILGPNGAGKSTLLRAL-SGElSPDSGEVRLNGRPLADWSPAELARRR-- 78

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2680999625  82 kvGLVFQQFHLVPYLTALENIMIAQYYHS-MPDEAEAL--AALDRVGLKDRAKHLPSQLSGG 140
Cdd:PRK13548   79 --AVLPQHSSLSFPFTVEEVVAMGRAPHGlSRAEDDALvaAALAQVDLAHLAGRDYPQLSGG 138
ABC_KpsT_Wzt cd03220
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ...
 13-104 4.79e-13

ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.


Pssm-ID: 213187 [Multi-domain]  Cd Length: 224  Bit Score: 63.32  E-value: 4.79e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625  13 YGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNsrnlttirrdkVGLVFQqfhl 92
Cdd:cd03220    32 VGEFWALKDVSFEVPRGERIGLIGRNGAGKSTLLRLLAGIYPPDSGTVTVRGRVSSLLG-----------LGGGFN---- 96

                          90
                  ....*....|..
gi 2680999625  93 vPYLTALENIMI 104
Cdd:cd03220    97 -PELTGRENIYL 107
dppF PRK11308
dipeptide transporter ATP-binding subunit; Provisional
 14-140 5.62e-13

dipeptide transporter ATP-binding subunit; Provisional


Pssm-ID: 236898 [Multi-domain]  Cd Length: 327  Bit Score: 64.22  E-value: 5.62e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625  14 GSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDIsTLNSRNLTTIRRDKVGLVFQQfhlv 93
Cdd:PRK11308   26 RLVKALDGVSFTLERGKTLAVVGESGCGKSTLARLLTMIETPTGGELYYQGQDL-LKADPEAQKLLRQKIQIVFQN---- 100

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2680999625  94 PYL---------TALENIMIAQYYHSMPDEAE-ALAALDRVGLK-DRAKHLPSQLSGG 140
Cdd:PRK11308  101 PYGslnprkkvgQILEEPLLINTSLSAAERREkALAMMAKVGLRpEHYDRYPHMFSGG 158
livF PRK11614
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;
1-108 6.41e-13

high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;


Pssm-ID: 183231 [Multi-domain]  Cd Length: 237  Bit Score: 63.36  E-value: 6.41e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   1 MSLLELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNSrnlTTIRR 80
Cdd:PRK11614    3 KVMLSFDKVSAHYGKIQALHEVSLHINQGEIVTLIGANGAGKTTLLGTLCGDPRATSGRIVFDGKDITDWQT---AKIMR 79

                          90       100
                  ....*....|....*....|....*...
gi 2680999625  81 DKVGLVFQQFHLVPYLTALENIMIAQYY 108
Cdd:PRK11614   80 EAVAIVPEGRRVFSRMTVEENLAMGGFF 107
Uup COG0488
ATPase components of ABC transporters with duplicated ATPase domains [General function ...
 3-140 9.26e-13

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];


Pssm-ID: 440254 [Multi-domain]  Cd Length: 520  Bit Score: 63.93  E-value: 9.26e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   3 LLELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILdGEDIstlnsrnlttirrdK 82
Cdd:COG0488   315 VLELEGLSKSYGDKTLLDDLSLRIDRGDRIGLIGPNGAGKSTLLKLLAGELEPDSGTVKL-GETV--------------K 379

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2680999625  83 VGlVFQQFH--LVPYLTALENImiaQYYHSMPDEAEALAALDRVGLK-DRAKHLPSQLSGG 140
Cdd:COG0488   380 IG-YFDQHQeeLDPDKTVLDEL---RDGAPGGTEQEVRGYLGRFLFSgDDAFKPVGVLSGG 436
PRK15439 PRK15439
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
 3-103 1.17e-12

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional


Pssm-ID: 185336 [Multi-domain]  Cd Length: 510  Bit Score: 63.53  E-value: 1.17e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   3 LLELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDIStlnsrNLTTIRRDK 82
Cdd:PRK15439   11 LLCARSISKQYSGVEVLKGIDFTLHAGEVHALLGGNGAGKSTLMKIIAGIVPPDSGTLEIGGNPCA-----RLTPAKAHQ 85

                          90       100
                  ....*....|....*....|...
gi 2680999625  83 VG--LVFQQFHLVPYLTALENIM 103
Cdd:PRK15439   86 LGiyLVPQEPLLFPNLSVKENIL 108
PRK11160 PRK11160
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
 3-140 1.24e-12

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed


Pssm-ID: 236865 [Multi-domain]  Cd Length: 574  Bit Score: 63.69  E-value: 1.24e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   3 LLELKDVSMIY--GSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNSRNLttirR 80
Cdd:PRK11160  338 SLTLNNVSFTYpdQPQPVLKGLSLQIKAGEKVALLGRTGCGKSTLLQLLTRAWDPQQGEILLNGQPIADYSEAAL----R 413

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2680999625  81 DKVGLVFQQFHLvpYLTAL-ENIMIAQyyhSMPDEAEALAALDRVGLkdrAKHLPS-------------QLSGG 140
Cdd:PRK11160  414 QAISVVSQRVHL--FSATLrDNLLLAA---PNASDEALIEVLQQVGL---EKLLEDdkglnawlgeggrQLSGG 479
3a01208 TIGR00958
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]
 3-140 1.34e-12

Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273363 [Multi-domain]  Cd Length: 711  Bit Score: 63.59  E-value: 1.34e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   3 LLELKDVSMIYGS---VKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNSRNLTTir 79
Cdd:TIGR00958 478 LIEFQDVSFSYPNrpdVPVLKGLTFTLHPGEVVALVGPSGSGKSTVAALLQNLYQPTGGQVLLDGVPLVQYDHHYLHR-- 555

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2680999625  80 rdKVGLVFQQfhlvPYL---TALENIMiaqYYHSMPDEAEALAALDRVGLKDRAKHLP-----------SQLSGG 140
Cdd:TIGR00958 556 --QVALVGQE----PVLfsgSVRENIA---YGLTDTPDEEIMAAAKAANAHDFIMEFPngydtevgekgSQLSGG 621
ABCF_EF-3 cd03221
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ...
 4-63 1.35e-12

ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.


Pssm-ID: 213188 [Multi-domain]  Cd Length: 144  Bit Score: 60.54  E-value: 1.35e-12
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   4 LELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILD 63
Cdd:cd03221     1 IELENLSKTYGGKLLLKDISLTINPGDRIGLVGRNGAGKSTLLKLIAGELEPDEGIVTWG 60
PRK11176 PRK11176
lipid A ABC transporter ATP-binding protein/permease MsbA;
4-92 1.59e-12

lipid A ABC transporter ATP-binding protein/permease MsbA;


Pssm-ID: 183016 [Multi-domain]  Cd Length: 582  Bit Score: 63.11  E-value: 1.59e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   4 LELKDVSMIYGS--VKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNSRNLttirRD 81
Cdd:PRK11176  342 IEFRNVTFTYPGkeVPALRNINFKIPAGKTVALVGRSGSGKSTIANLLTRFYDIDEGEILLDGHDLRDYTLASL----RN 417

                          90
                  ....*....|.
gi 2680999625  82 KVGLVFQQFHL 92
Cdd:PRK11176  418 QVALVSQNVHL 428
NupO COG3845
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ...
 3-140 1.72e-12

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];


Pssm-ID: 443055 [Multi-domain]  Cd Length: 504  Bit Score: 63.12  E-value: 1.72e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   3 LLELKDVSMI-YGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNSRnltTIRRD 81
Cdd:COG3845   257 VLEVENLSVRdDRGVPALKDVSLEVRAGEILGIAGVAGNGQSELAEALAGLRPPASGSIRLDGEDITGLSPR---ERRRL 333

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2680999625  82 KVGLVFQQFH---LVPYLTALENiMIAQYYHSMP---------DEAEALAA--LDRVGLKDRAKHLP-SQLSGG 140
Cdd:COG3845   334 GVAYIPEDRLgrgLVPDMSVAEN-LILGRYRRPPfsrggfldrKAIRAFAEelIEEFDVRTPGPDTPaRSLSGG 406
ABCC_ATM1_transporter cd03253
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ...
 4-88 2.26e-12

ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213220 [Multi-domain]  Cd Length: 236  Bit Score: 61.86  E-value: 2.26e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   4 LELKDVSMIYG-SVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLnsrNLTTIRRdK 82
Cdd:cd03253     1 IEFENVTFAYDpGRPVLKDVSFTIPAGKKVAIVGPSGSGKSTILRLLFRFYDVSSGSILIDGQDIREV---TLDSLRR-A 76


                  ....*.
gi 2680999625  83 VGLVFQ 88
Cdd:cd03253    77 IGVVPQ 82
PRK10762 PRK10762
D-ribose transporter ATP binding protein; Provisional
 3-140 3.25e-12

D-ribose transporter ATP binding protein; Provisional


Pssm-ID: 236755 [Multi-domain]  Cd Length: 501  Bit Score: 62.33  E-value: 3.25e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   3 LLELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNSRNlttIRRDK 82
Cdd:PRK10762    4 LLQLKGIDKAFPGVKALSGAALNVYPGRVMALVGENGAGKSTMMKVLTGIYTRDAGSILYLGKEVTFNGPKS---SQEAG 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2680999625  83 VGLVFQQFHLVPYLTALENIMIAQYYHS---------MPDEAEALaaLDRVGLKDRAKHLPSQLSGG 140
Cdd:PRK10762   81 IGIIHQELNLIPQLTIAENIFLGREFVNrfgridwkkMYAEADKL--LARLNLRFSSDKLVGELSIG 145
ABC_Carb_Monos_II cd03215
Second domain of the ATP-binding cassette component of monosaccharide transport system; This ...
 3-107 3.63e-12

Second domain of the ATP-binding cassette component of monosaccharide transport system; This family represents domain II of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. In members of Carb_Monos family the single hydrophobic gene product forms a homodimer, while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.


Pssm-ID: 213182 [Multi-domain]  Cd Length: 182  Bit Score: 60.14  E-value: 3.63e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   3 LLELKDVSMIygsvKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNSRNlttIRRDK 82
Cdd:cd03215     4 VLEVRGLSVK----GAVRDVSFEVRAGEIVGIAGLVGNGQTELAEALFGLRPPASGEITLDGKPVTRRSPRD---AIRAG 76

                          90       100
                  ....*....|....*....|....*...
gi 2680999625  83 VGLV---FQQFHLVPYLTALENIMIAQY 107
Cdd:cd03215    77 IAYVpedRKREGLVLDLSVAENIALSSL 104
PRK13651 PRK13651
cobalt transporter ATP-binding subunit; Provisional
 4-140 3.94e-12

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184210 [Multi-domain]  Cd Length: 305  Bit Score: 61.64  E-value: 3.94e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   4 LELKDVSMIYGS-----VKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNS------ 72
Cdd:PRK13651    3 IKVKNIVKIFNKklpteLKALDNVSVEINQGEFIAIIGQTGSGKTTFIEHLNALLLPDTGTIEWIFKDEKNKKKtkekek 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625  73 ---------------RNLTTIRRdKVGLVFQ--QFHLVPYlTALENIMI-AQYYHSMPDEAEALAA--LDRVGL-KDRAK 131
Cdd:PRK13651   83 vleklviqktrfkkiKKIKEIRR-RVGVVFQfaEYQLFEQ-TIEKDIIFgPVSMGVSKEEAKKRAAkyIELVGLdESYLQ 160


                  ....*....
gi 2680999625 132 HLPSQLSGG 140
Cdd:PRK13651  161 RSPFELSGG 169
PRK14246 PRK14246
phosphate ABC transporter ATP-binding protein; Provisional
 19-140 4.68e-12

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172734 [Multi-domain]  Cd Length: 257  Bit Score: 61.22  E-value: 4.68e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625  19 LQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDK------GTSGTVILDGEDISTLNSRNLttirRDKVGLVFQQFHL 92
Cdd:PRK14246   26 LKDITIKIPNNSIFGIMGPSGSGKSTLLKVLNRLIEiydskiKVDGKVLYFGKDIFQIDAIKL----RKEVGMVFQQPNP 101

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2680999625  93 VPYLTALENIMIAQYYHSMPDEAE----ALAALDRVGL----KDRAKHLPSQLSGG 140
Cdd:PRK14246  102 FPHLSIYDNIAYPLKSHGIKEKREikkiVEECLRKVGLwkevYDRLNSPASQLSGG 157
ArpD COG4618
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular ...
 19-75 4.72e-12

ABC-type protease/lipase transport system, ATPase and permease components [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 443660 [Multi-domain]  Cd Length: 563  Bit Score: 61.69  E-value: 4.72e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2680999625  19 LQNINLTVERGEWLAIMGPSGSGKTTLMN-IVGCMdKGTSGTVILDGEDISTLNSRNL 75
Cdd:COG4618   348 LRGVSFSLEPGEVLGVIGPSGSGKSTLARlLVGVW-PPTAGSVRLDGADLSQWDREEL 404
PRK15134 PRK15134
microcin C ABC transporter ATP-binding protein YejF; Provisional
 1-140 9.96e-12

microcin C ABC transporter ATP-binding protein YejF; Provisional


Pssm-ID: 237917 [Multi-domain]  Cd Length: 529  Bit Score: 60.87  E-value: 9.96e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   1 MSLLELKDVSMIY---GSVK-ALQNINLTVERGEWLAIMGPSGSGKT-TLMNIVGCMDKG----TSGTVILDGEDISTLN 71
Cdd:PRK15134    3 QPLLAIENLSVAFrqqQTVRtVVNDVSLQIEAGETLALVGESGSGKSvTALSILRLLPSPpvvyPSGDIRFHGESLLHAS 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625  72 SRNLTTIRRDKVGLVFQQfhlvPY--LTALENIMIAQY-----YHSMPDEA---EALAALDRVGLKDRAKHL---PSQLS 138
Cdd:PRK15134   83 EQTLRGVRGNKIAMIFQE----PMvsLNPLHTLEKQLYevlslHRGMRREAargEILNCLDRVGIRQAAKRLtdyPHQLS 158


                  ..
gi 2680999625 139 GG 140
Cdd:PRK15134  159 GG 160
fecE PRK11231
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;
4-140 1.27e-11

Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;


Pssm-ID: 183044 [Multi-domain]  Cd Length: 255  Bit Score: 60.03  E-value: 1.27e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   4 LELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNSRNLTTirrdKV 83
Cdd:PRK11231    3 LRTENLTVGYGTKRILNDLSLSLPTGKITALIGPNGCGKSTLLKCFARLLTPQSGTVFLGDKPISMLSSRQLAR----RL 78

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625  84 GLVFQQfHLVPyltalENIMIAQY--YHSMP-----------DEAEALAALDRVGLKDRAKHLPSQLSGG 140
Cdd:PRK11231   79 ALLPQH-HLTP-----EGITVRELvaYGRSPwlslwgrlsaeDNARVNQAMEQTRINHLADRRLTDLSGG 142
cbiO PRK13644
energy-coupling factor transporter ATPase;
3-140 1.34e-11

energy-coupling factor transporter ATPase;


Pssm-ID: 106587 [Multi-domain]  Cd Length: 274  Bit Score: 60.00  E-value: 1.34e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   3 LLELKDVSMIY-GSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGedISTLNSRNLTTIRRd 81
Cdd:PRK13644    1 MIRLENVSYSYpDGTPALENINLVIKKGEYIGIIGKNGSGKSTLALHLNGLLRPQKGKVLVSG--IDTGDFSKLQGIRK- 77

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2680999625  82 KVGLVFQ----QF--HLVPYLTAL--ENIMIAqyyhsmPDEAEALA--ALDRVGLKDRAKHLPSQLSGG 140
Cdd:PRK13644   78 LVGIVFQnpetQFvgRTVEEDLAFgpENLCLP------PIEIRKRVdrALAEIGLEKYRHRSPKTLSGG 140
cbiO PRK13646
energy-coupling factor transporter ATPase;
4-88 1.37e-11

energy-coupling factor transporter ATPase;


Pssm-ID: 184205 [Multi-domain]  Cd Length: 286  Bit Score: 60.18  E-value: 1.37e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   4 LELKDVSMIYG-----SVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDI-STLNSRNLTT 77
Cdd:PRK13646    3 IRFDNVSYTYQkgtpyEHQAIHDVNTEFEQGKYYAIVGQTGSGKSTLIQNINALLKPTTGTVTVDDITItHKTKDKYIRP 82

                          90
                  ....*....|.
gi 2680999625  78 IRRdKVGLVFQ 88
Cdd:PRK13646   83 VRK-RIGMVFQ 92
3a01204 TIGR00955
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ...
 19-104 1.56e-11

The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273361 [Multi-domain]  Cd Length: 617  Bit Score: 60.45  E-value: 1.56e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625  19 LQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMD-KGT--SGTVILDGEDIstlNSRNLTTIrrdkVGLVFQQFHLVPY 95
Cdd:TIGR00955  41 LKNVSGVAKPGELLAVMGSSGAGKTTLMNALAFRSpKGVkgSGSVLLNGMPI---DAKEMRAI----SAYVQQDDLFIPT 113


                  ....*....
gi 2680999625  96 LTALENIMI 104
Cdd:TIGR00955 114 LTVREHLMF 122
ABCC_Hemolysin cd03252
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ...
 4-89 1.78e-11

ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.


Pssm-ID: 213219 [Multi-domain]  Cd Length: 237  Bit Score: 59.42  E-value: 1.78e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   4 LELKDVSMIYG--SVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNSRNLttirRD 81
Cdd:cd03252     1 ITFEHVRFRYKpdGPVILDNISLRIKPGEVVGIVGRSGSGKSTLTKLIQRFYVPENGRVLVDGHDLALADPAWL----RR 76


                  ....*...
gi 2680999625  82 KVGLVFQQ 89
Cdd:cd03252    77 QVGVVLQE 84
PRK13537 PRK13537
nodulation factor ABC transporter ATP-binding protein NodI;
4-140 2.61e-11

nodulation factor ABC transporter ATP-binding protein NodI;


Pssm-ID: 237420 [Multi-domain]  Cd Length: 306  Bit Score: 59.43  E-value: 2.61e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   4 LELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNSRnlttiRRDKV 83
Cdd:PRK13537    8 IDFRNVEKRYGDKLVVDGLSFHVQRGECFGLLGPNGAGKTTTLRMLLGLTHPDAGSISLCGEPVPSRARH-----ARQRV 82

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625  84 GLVFQQFHLVPYLTALENIMIAQYYHSMPD-EAEALAA--LDRVGLKDRAKHLPSQLSGG 140
Cdd:PRK13537   83 GVVPQFDNLDPDFTVRENLLVFGRYFGLSAaAARALVPplLEFAKLENKADAKVGELSGG 142
PRK13539 PRK13539
cytochrome c biogenesis protein CcmA; Provisional
 4-140 3.07e-11

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 237421 [Multi-domain]  Cd Length: 207  Bit Score: 58.35  E-value: 3.07e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   4 LELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNsrnlttirrdkv 83
Cdd:PRK13539    3 LEGEDLACVRGGRVLFSGLSFTLAAGEALVLTGPNGSGKTTLLRLIAGLLPPAAGTIKLDGGDIDDPD------------ 70

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2680999625  84 glVFQQFHLV-------PYLTALENIMI-AQYYHSmpDEAEALAALDRVGLKDRAkHLPSQ-LSGG 140
Cdd:PRK13539   71 --VAEACHYLghrnamkPALTVAENLEFwAAFLGG--EELDIAAALEAVGLAPLA-HLPFGyLSAG 131
cbiO PRK13642
energy-coupling factor transporter ATPase;
3-140 3.43e-11

energy-coupling factor transporter ATPase;


Pssm-ID: 184202 [Multi-domain]  Cd Length: 277  Bit Score: 58.95  E-value: 3.43e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   3 LLELKDVSMIY---GSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNSRNLttir 79
Cdd:PRK13642    4 ILEVENLVFKYekeSDVNQLNGVSFSITKGEWVSIIGQNGSGKSTTARLIDGLFEEFEGKVKIDGELLTAENVWNL---- 79

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2680999625  80 RDKVGLVFQ----QFhlvPYLTALENIMIAQYYHSMPDEA------EALAALDRVGLKDRAkhlPSQLSGG 140
Cdd:PRK13642   80 RRKIGMVFQnpdnQF---VGATVEDDVAFGMENQGIPREEmikrvdEALLAVNMLDFKTRE---PARLSGG 144
cbiO PRK13640
energy-coupling factor transporter ATPase;
2-140 8.00e-11

energy-coupling factor transporter ATPase;


Pssm-ID: 184200 [Multi-domain]  Cd Length: 282  Bit Score: 57.89  E-value: 8.00e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   2 SLLELKDVSMIYGSVK--ALQNINLTVERGEWLAIMGPSGSGKTT---LMNIVGCMDKGTSGTVILDGediSTLNSRNLT 76
Cdd:PRK13640    4 NIVEFKHVSFTYPDSKkpALNDISFSIPRGSWTALIGHNGSGKSTiskLINGLLLPDDNPNSKITVDG---ITLTAKTVW 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2680999625  77 TIrRDKVGLVFQ----QF------HLVPYltALENIMIAQyyhsmPDEAEALA-ALDRVGLKDRAKHLPSQLSGG 140
Cdd:PRK13640   81 DI-REKVGIVFQnpdnQFvgatvgDDVAF--GLENRAVPR-----PEMIKIVRdVLADVGMLDYIDSEPANLSGG 147
PRK10261 PRK10261
glutathione transporter ATP-binding protein; Provisional
 16-140 9.07e-11

glutathione transporter ATP-binding protein; Provisional


Pssm-ID: 182342 [Multi-domain]  Cd Length: 623  Bit Score: 58.33  E-value: 9.07e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625  16 VKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNSRNLTTIRRDkVGLVFQQFH--LV 93
Cdd:PRK10261  337 VHAVEKVSFDLWPGETLSLVGESGSGKSTTGRALLRLVESQGGEIIFNGQRIDTLSPGKLQALRRD-IQFIFQDPYasLD 415

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2680999625  94 PYLTALENIMIAQYYHSMPDEAEALAA----LDRVGLK-DRAKHLPSQLSGG 140
Cdd:PRK10261  416 PRQTVGDSIMEPLRVHGLLPGKAAAARvawlLERVGLLpEHAWRYPHEFSGG 467
rim_protein TIGR01257
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...
 18-140 9.44e-11

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]


Pssm-ID: 130324 [Multi-domain]  Cd Length: 2272  Bit Score: 58.49  E-value: 9.44e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   18 ALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTlnsrNLTTIRRdKVGLVFQQFHLVPYLT 97
Cdd:TIGR01257  945 AVDRLNITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLVGGKDIET----NLDAVRQ-SLGMCPQHNILFHHLT 1019

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*.
gi 2680999625   98 ALENIMI-AQYYHSMPDEA--EALAALDRVGLKDRAKHLPSQLSGG 140
Cdd:TIGR01257 1020 VAEHILFyAQLKGRSWEEAqlEMEAMLEDTGLHHKRNEEAQDLSGG 1065
ABC_NatA_sodium_exporter cd03266
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ...
 14-137 1.01e-10

ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.


Pssm-ID: 213233 [Multi-domain]  Cd Length: 218  Bit Score: 56.99  E-value: 1.01e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625  14 GSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDIstlnSRNLTTIRRdKVGLVFQQFHLV 93
Cdd:cd03266    16 KTVQAVDGVSFTVKPGEVTGLLGPNGAGKTTTLRMLAGLLEPDAGFATVDGFDV----VKEPAEARR-RLGFVSDSTGLY 90

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 2680999625  94 PYLTALENImiaQYYhsmpdeaEALAALDRVGLKDRAKHLPSQL 137
Cdd:cd03266    91 DRLTARENL---EYF-------AGLYGLKGDELTARLEELADRL 124
PRK10253 PRK10253
iron-enterobactin ABC transporter ATP-binding protein;
9-140 1.20e-10

iron-enterobactin ABC transporter ATP-binding protein;


Pssm-ID: 182336 [Multi-domain]  Cd Length: 265  Bit Score: 57.30  E-value: 1.20e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   9 VSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNSRNLTtiRRdkVGLVFQ 88
Cdd:PRK10253   13 LTLGYGKYTVAENLTVEIPDGHFTAIIGPNGCGKSTLLRTLSRLMTPAHGHVWLDGEHIQHYASKEVA--RR--IGLLAQ 88

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2680999625  89 QFHLVPYLTALENIMIAQYYHS-------MPDEAEALAALDRVGLKDRAKHLPSQLSGG 140
Cdd:PRK10253   89 NATTPGDITVQELVARGRYPHQplftrwrKEDEEAVTKAMQATGITHLADQSVDTLSGG 147
phnK PRK11701
phosphonate C-P lyase system protein PhnK; Provisional
 3-140 2.81e-10

phosphonate C-P lyase system protein PhnK; Provisional


Pssm-ID: 183280 [Multi-domain]  Cd Length: 258  Bit Score: 56.09  E-value: 2.81e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   3 LLELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGE-----DISTLNSRNLTT 77
Cdd:PRK11701    6 LLSVRGLTKLYGPRKGCRDVSFDLYPGEVLGIVGESGSGKTTLLNALSARLAPDAGEVHYRMRdgqlrDLYALSEAERRR 85

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2680999625  78 IRRDKVGLVFQqfH----LVPYLTALENI----MIAQYYHSMPDEAEALAALDRVGL-KDRAKHLPSQLSGG 140
Cdd:PRK11701   86 LLRTEWGFVHQ--HprdgLRMQVSAGGNIgerlMAVGARHYGDIRATAGDWLERVEIdAARIDDLPTTFSGG 155
cbiO PRK13643
energy-coupling factor transporter ATPase;
17-140 2.97e-10

energy-coupling factor transporter ATPase;


Pssm-ID: 184203 [Multi-domain]  Cd Length: 288  Bit Score: 56.28  E-value: 2.97e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625  17 KALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTV-ILDGEDISTLNSRNLTTIRRdKVGLVFQ--QFHLV 93
Cdd:PRK13643   20 RALFDIDLEVKKGSYTALIGHTGSGKSTLLQHLNGLLQPTEGKVtVGDIVVSSTSKQKEIKPVRK-KVGVVFQfpESQLF 98

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2680999625  94 PYlTALENIMIA-QYYHSMPDEAEALAA--LDRVGL-KDRAKHLPSQLSGG 140
Cdd:PRK13643   99 EE-TVLKDVAFGpQNFGIPKEKAEKIAAekLEMVGLaDEFWEKSPFELSGG 148
ycf16 CHL00131
sulfate ABC transporter protein; Validated
 2-67 2.98e-10

sulfate ABC transporter protein; Validated


Pssm-ID: 214372 [Multi-domain]  Cd Length: 252  Bit Score: 56.19  E-value: 2.98e-10
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2680999625   2 SLLELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMD--KGTSGTVILDGEDI 67
Cdd:CHL00131    6 PILEIKNLHASVNENEILKGLNLSINKGEIHAIMGPNGSGKSTLSKVIAGHPayKILEGDILFKGESI 73
PRK10522 PRK10522
multidrug transporter membrane component/ATP-binding component; Provisional
 4-132 3.34e-10

multidrug transporter membrane component/ATP-binding component; Provisional


Pssm-ID: 236707 [Multi-domain]  Cd Length: 547  Bit Score: 56.52  E-value: 3.34e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   4 LELKDVSMIYGSVK-ALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNSRNLttirRDK 82
Cdd:PRK10522  323 LELRNVTFAYQDNGfSVGPINLTIKRGELLFLIGGNGSGKSTLAMLLTGLYQPQSGEILLDGKPVTAEQPEDY----RKL 398

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 2680999625  83 VGLVFQQFHLVPYLTALENimiaqyyhSMPDEAEALAALDRVGLKDRAKH 132
Cdd:PRK10522  399 FSAVFTDFHLFDQLLGPEG--------KPANPALVEKWLERLKMAHKLEL 440
PRK14271 PRK14271
phosphate ABC transporter ATP-binding protein; Provisional
 33-140 3.84e-10

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172759 [Multi-domain]  Cd Length: 276  Bit Score: 55.87  E-value: 3.84e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625  33 AIMGPSGSGKTTLMNIVGCMDKGT-----SGTVILDGEDIstLNSRNLTTIRRdKVGLVFQQFHLVPyLTALENIMIAQY 107
Cdd:PRK14271   51 SLMGPTGSGKTTFLRTLNRMNDKVsgyrySGDVLLGGRSI--FNYRDVLEFRR-RVGMLFQRPNPFP-MSIMDNVLAGVR 126

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 2680999625 108 YHSMPDEAE----ALAALDRVGL----KDRAKHLPSQLSGG 140
Cdd:PRK14271  127 AHKLVPRKEfrgvAQARLTEVGLwdavKDRLSDSPFRLSGG 167
dppD PRK11022
dipeptide transporter ATP-binding subunit; Provisional
 1-140 4.01e-10

dipeptide transporter ATP-binding subunit; Provisional


Pssm-ID: 182906 [Multi-domain]  Cd Length: 326  Bit Score: 56.29  E-value: 4.01e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   1 MSLLELKDVSMIYGSV----KALQNINLTVERGEWLAIMGPSGSGKT-TLMNIVGCMD---KGTSGTVILDGEDISTLNS 72
Cdd:PRK11022    1 MALLNVDKLSVHFGDEsapfRAVDRISYSVKQGEVVGIVGESGSGKSvSSLAIMGLIDypgRVMAEKLEFNGQDLQRISE 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2680999625  73 RNLTTIRRDKVGLVFQQ--FHLVPYLTALENIMIAQYYHSMPDEAE----ALAALDRVGLKDRAKHL---PSQLSGG 140
Cdd:PRK11022   81 KERRNLVGAEVAMIFQDpmTSLNPCYTVGFQIMEAIKVHQGGNKKTrrqrAIDLLNQVGIPDPASRLdvyPHQLSGG 157
PRK10575 PRK10575
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;
6-140 4.27e-10

Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;


Pssm-ID: 182561 [Multi-domain]  Cd Length: 265  Bit Score: 55.95  E-value: 4.27e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   6 LKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNSRNLTTirrdKVGL 85
Cdd:PRK10575   14 LRNVSFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFAR----KVAY 89

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2680999625  86 VFQQFHLVPYLTALENIMIAQY-YH------SMPDEAEALAALDRVGLKDRAKHLPSQLSGG 140
Cdd:PRK10575   90 LPQQLPAAEGMTVRELVAIGRYpWHgalgrfGAADREKVEEAISLVGLKPLAHRLVDSLSGG 151
PRK10790 PRK10790
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;
4-137 4.64e-10

SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;


Pssm-ID: 182733 [Multi-domain]  Cd Length: 592  Bit Score: 56.26  E-value: 4.64e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   4 LELKDVSMIYGSVK-ALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNSRNLttirRDK 82
Cdd:PRK10790  341 IDIDNVSFAYRDDNlVLQNINLSVPSRGFVALVGHTGSGKSTLASLLMGYYPLTEGEIRLDGRPLSSLSHSVL----RQG 416

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2680999625  83 VGLVfQQFHLVPYLTALENIMIAQYYhsmpDEAEALAALDRVGLKDRAKHLPSQL 137
Cdd:PRK10790  417 VAMV-QQDPVVLADTFLANVTLGRDI----SEEQVWQALETVQLAELARSLPDGL 466
PRK10895 PRK10895
lipopolysaccharide ABC transporter ATP-binding protein; Provisional
 1-103 1.00e-09

lipopolysaccharide ABC transporter ATP-binding protein; Provisional


Pssm-ID: 182817 [Multi-domain]  Cd Length: 241  Bit Score: 54.51  E-value: 1.00e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   1 MSLLELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLnsrNLTTIRR 80
Cdd:PRK10895    1 MATLTAKNLAKAYKGRRVVEDVSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRDAGNIIIDDEDISLL---PLHARAR 77

                          90       100
                  ....*....|....*....|...
gi 2680999625  81 DKVGLVFQQFHLVPYLTALENIM 103
Cdd:PRK10895   78 RGIGYLPQEASIFRRLSVYDNLM 100
YddA COG4178
ABC-type uncharacterized transport system, permease and ATPase components [General function ...
 19-140 1.33e-09

ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only];


Pssm-ID: 443337 [Multi-domain]  Cd Length: 571  Bit Score: 54.81  E-value: 1.33e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625  19 LQNINLTVERGEWLAIMGPSGSGKTTLMN-IVGCMDKGtSGTVIL-DGEDISTLNSRnlttirrdkvglvfqqfhlvPYL 96
Cdd:COG4178   379 LEDLSLSLKPGERLLITGPSGSGKSTLLRaIAGLWPYG-SGRIARpAGARVLFLPQR--------------------PYL 437

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2680999625  97 ------TALenimiaqYY---HSMPDEAEALAALDRVGLKDRAKHL------PSQLSGG 140
Cdd:COG4178   438 plgtlrEAL-------LYpatAEAFSDAELREALEAVGLGHLAERLdeeadwDQVLSLG 489
PRK15134 PRK15134
microcin C ABC transporter ATP-binding protein YejF; Provisional
 18-140 1.52e-09

microcin C ABC transporter ATP-binding protein YejF; Provisional


Pssm-ID: 237917 [Multi-domain]  Cd Length: 529  Bit Score: 54.71  E-value: 1.52e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625  18 ALQNINLTVERGEWLAIMGPSGSGKTT----LMNIVgcmdkGTSGTVILDGEDISTLNSRNLTTIRRdKVGLVFQQFH-- 91
Cdd:PRK15134  301 VVKNISFTLRPGETLGLVGESGSGKSTtglaLLRLI-----NSQGEIWFDGQPLHNLNRRQLLPVRH-RIQVVFQDPNss 374

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2680999625  92 LVPYLTALENIMIAQYYH-----SMPDEAEALAALDRVGLKDRAKH-LPSQLSGG 140
Cdd:PRK15134  375 LNPRLNVLQIIEEGLRVHqptlsAAQREQQVIAVMEEVGLDPETRHrYPAEFSGG 429
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
5-140 2.04e-09

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 54.36  E-value: 2.04e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   5 ELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNivgcMDKG----TSGTVILDGEDIstlNSRNLTTIRR 80
Cdd:NF033858  268 EARGLTMRFGDFTAVDHVSFRIRRGEIFGFLGSNGCGKSTTMK----MLTGllpaSEGEAWLFGQPV---DAGDIATRRR 340

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2680999625  81 dkVGLVFQQFHLVPYLTALENIMI-AQYYHSMPDEAEAL--AALDRVGLKDRAKHLPSQLSGG 140
Cdd:NF033858  341 --VGYMSQAFSLYGELTVRQNLELhARLFHLPAAEIAARvaEMLERFDLADVADALPDSLPLG 401
PvdE COG4615
ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion ...
 4-128 2.04e-09

ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion transport and metabolism];


Pssm-ID: 443659 [Multi-domain]  Cd Length: 547  Bit Score: 54.42  E-value: 2.04e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   4 LELKDVSMIYGSVK-----ALQNINLTVERGEWLAIMGPSGSGKTTLMN-IVGCMdKGTSGTVILDGEDISTLNS---RN 74
Cdd:COG4615   328 LELRGVTYRYPGEDgdegfTLGPIDLTIRRGELVFIVGGNGSGKSTLAKlLTGLY-RPESGEILLDGQPVTADNReayRQ 406

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2680999625  75 LTTIrrdkvglVFQQFHLVPYLTALENimiaqyyhsMPDEAEALAALDRVGLKD 128
Cdd:COG4615   407 LFSA-------VFSDFHLFDRLLGLDG---------EADPARARELLERLELDH 444
ABC_NatA_like cd03267
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ...
 13-89 2.32e-09

ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.


Pssm-ID: 213234 [Multi-domain]  Cd Length: 236  Bit Score: 53.49  E-value: 2.32e-09
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2680999625  13 YGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNSRNLTTIrrdkvGLVFQQ 89
Cdd:cd03267    31 YREVEALKGISFTIEKGEIVGFIGPNGAGKTTTLKILSGLLQPTSGEVRVAGLVPWKRRKKFLRRI-----GVVFGQ 102
PRK13536 PRK13536
nodulation factor ABC transporter ATP-binding protein NodI;
4-140 2.40e-09

nodulation factor ABC transporter ATP-binding protein NodI;


Pssm-ID: 237419 [Multi-domain]  Cd Length: 340  Bit Score: 54.07  E-value: 2.40e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   4 LELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTlNSRnlttIRRDKV 83
Cdd:PRK13536   42 IDLAGVSKSYGDKAVVNGLSFTVASGECFGLLGPNGAGKSTIARMILGMTSPDAGKITVLGVPVPA-RAR----LARARI 116

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625  84 GLVFQQFHLVPYLTALENIMIAQYYHSMPD-EAEAL--AALDRVGLKDRAKHLPSQLSGG 140
Cdd:PRK13536  117 GVVPQFDNLDLEFTVRENLLVFGRYFGMSTrEIEAVipSLLEFARLESKADARVSDLSGG 176
cbiO PRK13647
cobalt transporter ATP-binding subunit; Provisional
 4-140 2.98e-09

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237457 [Multi-domain]  Cd Length: 274  Bit Score: 53.59  E-value: 2.98e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   4 LELKDVSMIY-GSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNSRNLttirRDK 82
Cdd:PRK13647    5 IEVEDLHFRYkDGTKALKGLSLSIPEGSKTALLGPNGAGKSTLLLHLNGIYLPQRGRVKVMGREVNAENEKWV----RSK 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2680999625  83 VGLVFQ----QfhlVPYLTALENIMIAQYYHSM-PDEAE--ALAALDRVGLKDRAKHLPSQLSGG 140
Cdd:PRK13647   81 VGLVFQdpddQ---VFSSTVWDDVAFGPVNMGLdKDEVErrVEEALKAVRMWDFRDKPPYHLSYG 142
ABC_CcmA_heme_exporter cd03231
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ...
 19-140 6.87e-09

Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.


Pssm-ID: 213198 [Multi-domain]  Cd Length: 201  Bit Score: 51.72  E-value: 6.87e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625  19 LQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGedisTLNSRNLTTIRRDKVGLVFQQfHLVPYLTA 98
Cdd:cd03231    16 FSGLSFTLAAGEALQVTGPNGSGKTTLLRILAGLSPPLAGRVLLNG----GPLDFQRDSIARGLLYLGHAP-GIKTTLSV 90

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 2680999625  99 LENImiaQYYHSMPDEAEALAALDRVGLKDrAKHLP-SQLSGG 140
Cdd:cd03231    91 LENL---RFWHADHSDEQVEEALARVGLNG-FEDRPvAQLSAG 129
ABCC_MRP_domain1 cd03250
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ...
 4-64 7.52e-09

ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213217 [Multi-domain]  Cd Length: 204  Bit Score: 51.70  E-value: 7.52e-09
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2680999625   4 LELKDVSMIYGSVK-----ALQNINLTVERGEWLAIMGPSGSGKTTLMN-IVGCMDKgTSGTVILDG 64
Cdd:cd03250     1 ISVEDASFTWDSGEqetsfTLKDINLEVPKGELVAIVGPVGSGKSSLLSaLLGELEK-LSGSVSVPG 66
MglA COG1129
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
3-131 9.63e-09

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440745 [Multi-domain]  Cd Length: 497  Bit Score: 52.33  E-value: 9.63e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   3 LLELKDVSmiygSVKALQNINLTVERGEWLAIMGPSGSGKTTLMN-IVGcMDKGTSGTVILDGEDISTLNSRnlTTIRRd 81
Cdd:COG1129   256 VLEVEGLS----VGGVVRDVSFSVRAGEILGIAGLVGAGRTELARaLFG-ADPADSGEIRLDGKPVRIRSPR--DAIRA- 327

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2680999625  82 kvGLVF-----QQFHLVPYLTALENIMIAqyyhsmpdeaeALAALDRVGLKDRAK 131
Cdd:COG1129   328 --GIAYvpedrKGEGLVLDLSIRENITLA-----------SLDRLSRGGLLDRRR 369
znuC PRK09544
high-affinity zinc transporter ATPase; Reviewed
 1-140 1.01e-08

high-affinity zinc transporter ATPase; Reviewed


Pssm-ID: 181939 [Multi-domain]  Cd Length: 251  Bit Score: 52.04  E-value: 1.01e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   1 MSLLELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGedistlnsrnlttirR 80
Cdd:PRK09544    2 TSLVSLENVSVSFGQRRVLSDVSLELKPGKILTLLGPNGAGKSTLVRVVLGLVAPDEGVIKRNG---------------K 66

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2680999625  81 DKVGLVFQQFHLVPYLTalenIMIAQYYHSMP--DEAEALAALDRVglkdRAKHL---PSQ-LSGG 140
Cdd:PRK09544   67 LRIGYVPQKLYLDTTLP----LTVNRFLRLRPgtKKEDILPALKRV----QAGHLidaPMQkLSGG 124
PRK10982 PRK10982
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
 6-107 1.58e-08

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional


Pssm-ID: 182880 [Multi-domain]  Cd Length: 491  Bit Score: 51.65  E-value: 1.58e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   6 LKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNSRNLTtirRDKVGL 85
Cdd:PRK10982    1 MSNISKSFPGVKALDNVNLKVRPHSIHALMGENGAGKSTLLKCLFGIYQKDSGSILFQGKEIDFKSSKEAL---ENGISM 77

                          90       100
                  ....*....|....*....|..
gi 2680999625  86 VFQQFHLVPYLTALENIMIAQY 107
Cdd:PRK10982   78 VHQELNLVLQRSVMDNMWLGRY 99
ABCC_TAP cd03248
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; ...
 3-89 1.63e-08

ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; TAP (Transporter Associated with Antigen Processing) is essential for peptide delivery from the cytosol into the lumen of the endoplasmic reticulum (ER), where these peptides are loaded on major histocompatibility complex (MHC) I molecules. Loaded MHC I leave the ER and display their antigenic cargo on the cell surface to cytotoxic T cells. Subsequently, virus-infected or malignantly transformed cells can be eliminated. TAP belongs to the large family of ATP-binding cassette (ABC) transporters, which translocate a vast variety of solutes across membranes.


Pssm-ID: 213215 [Multi-domain]  Cd Length: 226  Bit Score: 50.93  E-value: 1.63e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   3 LLELKDVSMIYGS---VKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNSRNLttir 79
Cdd:cd03248    11 IVKFQNVTFAYPTrpdTLVLQDVSFTLHPGEVTALVGPSGSGKSTVVALLENFYQPQGGQVLLDGKPISQYEHKYL---- 86

                          90
                  ....*....|
gi 2680999625  80 RDKVGLVFQQ 89
Cdd:cd03248    87 HSKVSLVGQE 96
nikD PRK10418
nickel transporter ATP-binding protein NikD; Provisional
 4-140 1.89e-08

nickel transporter ATP-binding protein NikD; Provisional


Pssm-ID: 236688 [Multi-domain]  Cd Length: 254  Bit Score: 51.24  E-value: 1.89e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   4 LELKDVSmIYGSVKALQNINLTVERGEWLAIMGPSGSGKT-TLMNIVGCMDKG---TSGTVILDGEDIStlnsrnLTTIR 79
Cdd:PRK10418    5 IELRNIA-LQAAQPLVHGVSLTLQRGRVLALVGGSGSGKSlTCAAALGILPAGvrqTAGRVLLDGKPVA------PCALR 77

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2680999625  80 RDKVGLVFQQ----FHlvPYLT----ALENIMIAQyyhSMPDEAEALAALDRVGLKDRAKHL---PSQLSGG 140
Cdd:PRK10418   78 GRKIATIMQNprsaFN--PLHTmhthARETCLALG---KPADDATLTAALEAVGLENAARVLklyPFEMSGG 144
PRK14243 PRK14243
phosphate transporter ATP-binding protein; Provisional
 3-140 3.05e-08

phosphate transporter ATP-binding protein; Provisional


Pssm-ID: 184588 [Multi-domain]  Cd Length: 264  Bit Score: 50.55  E-value: 3.05e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   3 LLELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTL------MN--IVGCMdkgTSGTVILDGEDISTlNSRN 74
Cdd:PRK14243   10 VLRTENLNVYYGSFLAVKNVWLDIPKNQITAFIGPSGCGKSTIlrcfnrLNdlIPGFR---VEGKVTFHGKNLYA-PDVD 85

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2680999625  75 LTTIRRdKVGLVFQQFHLVPYlTALENIM----IAQYYHSMPDEAE-AL--AAL-DRVglKDRAKHLPSQLSGG 140
Cdd:PRK14243   86 PVEVRR-RIGMVFQKPNPFPK-SIYDNIAygarINGYKGDMDELVErSLrqAALwDEV--KDKLKQSGLSLSGG 155
cbiO PRK13636
cobalt transporter ATP-binding subunit; Provisional
 3-88 4.96e-08

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184196 [Multi-domain]  Cd Length: 283  Bit Score: 50.23  E-value: 4.96e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   3 LLELKDVSMIYGS-VKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTlnSRNLTTIRRD 81
Cdd:PRK13636    5 ILKVEELNYNYSDgTHALKGININIKKGEVTAILGGNGAGKSTLFQNLNGILKPSSGRILFDGKPIDY--SRKGLMKLRE 82


                  ....*..
gi 2680999625  82 KVGLVFQ 88
Cdd:PRK13636   83 SVGMVFQ 89
modC PRK11144
molybdenum ABC transporter ATP-binding protein ModC;
33-140 5.29e-08

molybdenum ABC transporter ATP-binding protein ModC;


Pssm-ID: 182993 [Multi-domain]  Cd Length: 352  Bit Score: 50.26  E-value: 5.29e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625  33 AIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGediSTLNSR----NLTTIRRdKVGLVFQQFHLVPYLTALENImiaQY- 107
Cdd:PRK11144   28 AIFGRSGAGKTSLINAISGLTRPQKGRIVLNG---RVLFDAekgiCLPPEKR-RIGYVFQDARLFPHYKVRGNL---RYg 100

                          90       100       110
                  ....*....|....*....|....*....|....
gi 2680999625 108 -YHSMPDEAEALAALdrVGLKDRAKHLPSQLSGG 140
Cdd:PRK11144  101 mAKSMVAQFDKIVAL--LGIEPLLDRYPGSLSGG 132
ABCD_peroxisomal_ALDP cd03223
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding ...
 19-50 1.14e-07

ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding cassette transporter (Pat) is involved in the import of very long-chain fatty acids (VLCFA) into the peroxisome. The peroxisomal membrane forms a permeability barrier for a wide variety of metabolites required for and formed during fatty acid beta-oxidation. To communicate with the cytoplasm and mitochondria, peroxisomes need dedicated proteins to transport such hydrophilic molecules across their membranes. X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ALD gene, which encodes ALDP (adrenoleukodystrophy protein ), a peroxisomal integral membrane protein that is a member of the ATP-binding cassette (ABC) transporter protein family. The disease is characterized by a striking and unpredictable variation in phenotypic expression. Phenotypes include the rapidly progressive childhood cerebral form (CCALD), the milder adult form, adrenomyeloneuropathy (AMN), and variants without neurologic involvement (i.e. asymptomatic).


Pssm-ID: 213190 [Multi-domain]  Cd Length: 166  Bit Score: 47.92  E-value: 1.14e-07
                          10        20        30
                  ....*....|....*....|....*....|..
gi 2680999625  19 LQNINLTVERGEWLAIMGPSGSGKTTLMNIVG 50
Cdd:cd03223    17 LKDLSFEIKPGDRLLITGPSGTGKSSLFRALA 48
PRK10938 PRK10938
putative molybdenum transport ATP-binding protein ModF; Provisional
 3-140 1.40e-07

putative molybdenum transport ATP-binding protein ModF; Provisional


Pssm-ID: 182852 [Multi-domain]  Cd Length: 490  Bit Score: 48.86  E-value: 1.40e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   3 LLELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIV-GCMDKGTSGTVIL------DGEDIstlnsrnl 75
Cdd:PRK10938  260 RIVLNNGVVSYNDRPILHNLSWQVNPGEHWQIVGPNGAGKSTLLSLItGDHPQGYSNDLTLfgrrrgSGETI-------- 331

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2680999625  76 TTIRRdKVGLVFQQFHLvPYL--TALENIMIAQY------YHSMPDEAEALAA--LDRVGLKDRAKHLPSQ-LSGG 140
Cdd:PRK10938  332 WDIKK-HIGYVSSSLHL-DYRvsTSVRNVILSGFfdsigiYQAVSDRQQKLAQqwLDILGIDKRTADAPFHsLSWG 405
ABCG_PDR_domain2 cd03232
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding ...
 8-104 1.54e-07

Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213199 [Multi-domain]  Cd Length: 192  Bit Score: 48.01  E-value: 1.54e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   8 DVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGcmDKGTSGTVilDGEdiSTLNSRNLTTIRRDKVGLVF 87
Cdd:cd03232    12 TVPVKGGKRQLLNNISGYVKPGTLTALMGESGAGKTTLLDVLA--GRKTAGVI--TGE--ILINGRPLDKNFQRSTGYVE 85

                          90
                  ....*....|....*..
gi 2680999625  88 QQFHLVPYLTALENIMI 104
Cdd:cd03232    86 QQDVHSPNLTVREALRF 102
COG4586 COG4586
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
 16-89 2.43e-07

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 443643 [Multi-domain]  Cd Length: 323  Bit Score: 48.16  E-value: 2.43e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2680999625  16 VKALQNINLTVERGEWLAIMGPSGSGKTTLMNivgcMDKG----TSGTVILDGEDISTLNSRNLTTIrrdkvGLVFQQ 89
Cdd:COG4586    35 VEAVDDISFTIEPGEIVGFIGPNGAGKSTTIK----MLTGilvpTSGEVRVLGYVPFKRRKEFARRI-----GVVFGQ 103
PRK15079 PRK15079
oligopeptide ABC transporter ATP-binding protein OppF; Provisional
 15-140 2.50e-07

oligopeptide ABC transporter ATP-binding protein OppF; Provisional


Pssm-ID: 185037 [Multi-domain]  Cd Length: 331  Bit Score: 48.16  E-value: 2.50e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625  15 SVKALQNINLTVERGEWLAIMGPSGSGKTTLMN-IVGCMdKGTSGTVILDGEDISTLNSRNLTTIRRDkVGLVFQQ--FH 91
Cdd:PRK15079   33 TLKAVDGVTLRLYEGETLGVVGESGCGKSTFARaIIGLV-KATDGEVAWLGKDLLGMKDDEWRAVRSD-IQMIFQDplAS 110

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2680999625  92 LVPYLTALEniMIAQ----YYHSMPDEA---EALAALDRVGL-KDRAKHLPSQLSGG 140
Cdd:PRK15079  111 LNPRMTIGE--IIAEplrtYHPKLSRQEvkdRVKAMMLKVGLlPNLINRYPHEFSGG 165
PRK15064 PRK15064
ABC transporter ATP-binding protein; Provisional
 4-56 3.34e-07

ABC transporter ATP-binding protein; Provisional


Pssm-ID: 237894 [Multi-domain]  Cd Length: 530  Bit Score: 47.96  E-value: 3.34e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2680999625   4 LELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMN-IVGCM--DKGT 56
Cdd:PRK15064  320 LEVENLTKGFDNGPLFKNLNLLLEAGERLAIIGENGVGKTTLLRtLVGELepDSGT 375
ATM1 COG5265
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components ...
 19-88 3.45e-07

ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444078 [Multi-domain]  Cd Length: 605  Bit Score: 47.89  E-value: 3.45e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2680999625  19 LQNINLTVERGEWLAIMGPSGSGKTTLMNI------VgcmdkgTSGTVILDGEDISTLNSRNLttirRDKVGLVFQ 88
Cdd:COG5265   374 LKGVSFEVPAGKTVAIVGPSGAGKSTLARLlfrfydV------TSGRILIDGQDIRDVTQASL----RAAIGIVPQ 439
PRK11174 PRK11174
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
 19-134 5.05e-07

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed


Pssm-ID: 236870 [Multi-domain]  Cd Length: 588  Bit Score: 47.53  E-value: 5.05e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625  19 LQNINLTVERGEWLAIMGPSGSGKTTLMN-IVGCMDkgTSGTVILDGEDISTLnsrNLTTIRRdKVGLVFQQFHLvPYLT 97
Cdd:PRK11174  366 AGPLNFTLPAGQRIALVGPSGAGKTSLLNaLLGFLP--YQGSLKINGIELREL---DPESWRK-HLSWVGQNPQL-PHGT 438

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 2680999625  98 ALENIMIAQyyHSMPDEaEALAALDRVGLKDRAKHLP 134
Cdd:PRK11174  439 LRDNVLLGN--PDASDE-QLQQALENAWVSEFLPLLP 472
ABCC_NFT1 cd03369
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type ...
 4-80 5.62e-07

ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type transporter 1). NFT1 belongs to the MRP (multidrug resistance-associated protein) family of ABC transporters. Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213269 [Multi-domain]  Cd Length: 207  Bit Score: 46.64  E-value: 5.62e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2680999625   4 LELKDVSMIYGS--VKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLnsrNLTTIRR 80
Cdd:cd03369     7 IEVENLSVRYAPdlPPVLKNVSFKVKAGEKIGIVGRTGAGKSTLILALFRFLEAEEGKIEIDGIDISTI---PLEDLRS 82
PRK09700 PRK09700
D-allose ABC transporter ATP-binding protein AlsA;
17-68 7.65e-07

D-allose ABC transporter ATP-binding protein AlsA;


Pssm-ID: 182036 [Multi-domain]  Cd Length: 510  Bit Score: 47.09  E-value: 7.65e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2680999625  17 KALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDIS 68
Cdd:PRK09700  277 KKVRDISFSVCRGEILGFAGLVGSGRTELMNCLFGVDKRAGGEIRLNGKDIS 328
PLN03211 PLN03211
ABC transporter G-25; Provisional
 29-103 1.16e-06

ABC transporter G-25; Provisional


Pssm-ID: 215634 [Multi-domain]  Cd Length: 659  Bit Score: 46.41  E-value: 1.16e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2680999625  29 GEWLAIMGPSGSGKTTLMNIVGCMDKGTS--GTVIldgedistLNSRNLTTIRRDKVGLVFQQFHLVPYLTALENIM 103
Cdd:PLN03211   94 GEILAVLGPSGSGKSTLLNALAGRIQGNNftGTIL--------ANNRKPTKQILKRTGFVTQDDILYPHLTVRETLV 162
PRK10261 PRK10261
glutathione transporter ATP-binding protein; Provisional
 14-140 1.49e-06

glutathione transporter ATP-binding protein; Provisional


Pssm-ID: 182342 [Multi-domain]  Cd Length: 623  Bit Score: 46.00  E-value: 1.49e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625  14 GSVKALQNINLTVERGEWLAIMGPSGSGKT----TLMNIVgcmdKGTSGTVILDGE----------DISTLNSRNLTTIR 79
Cdd:PRK10261   27 QKIAAVRNLSFSLQRGETLAIVGESGSGKSvtalALMRLL----EQAGGLVQCDKMllrrrsrqviELSEQSAAQMRHVR 102

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625  80 RDKVGLVFQQ--FHLVPYLTALENIMIAQYYHSMPDEAEALAA----LDRVGLKDRAKHL---PSQLSGG 140
Cdd:PRK10261  103 GADMAMIFQEpmTSLNPVFTVGEQIAESIRLHQGASREEAMVEakrmLDQVRIPEAQTILsryPHQLSGG 172
PRK11147 PRK11147
ABC transporter ATPase component; Reviewed
 1-63 1.50e-06

ABC transporter ATPase component; Reviewed


Pssm-ID: 236861 [Multi-domain]  Cd Length: 635  Bit Score: 46.10  E-value: 1.50e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2680999625   1 MSLLELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVgcmdkgtSGTVILD 63
Cdd:PRK11147    1 MSLISIHGAWLSFSDAPLLDNAELHIEDNERVCLVGRNGAGKSTLMKIL-------NGEVLLD 56
cbiO PRK13631
cobalt transporter ATP-binding subunit; Provisional
 3-140 1.84e-06

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237451 [Multi-domain]  Cd Length: 320  Bit Score: 45.61  E-value: 1.84e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   3 LLELKDVSMIYGS-----VKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTV----ILDGEDISTLNSR 73
Cdd:PRK13631   21 ILRVKNLYCVFDEkqeneLVALNNISYTFEKNKIYFIIGNSGSGKSTLVTHFNGLIKSKYGTIqvgdIYIGDKKNNHELI 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625  74 NLTTIR--------RDKVGLVFQ--QFHLvpYLTALE-NIMIAQYYHSMP-DEAEALAA--LDRVGLK----DRAkhlPS 135
Cdd:PRK13631  101 TNPYSKkiknfkelRRRVSMVFQfpEYQL--FKDTIEkDIMFGPVALGVKkSEAKKLAKfyLNKMGLDdsylERS---PF 175


                  ....*
gi 2680999625 136 QLSGG 140
Cdd:PRK13631  176 GLSGG 180
SapD COG4170
ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];
1-140 3.06e-06

ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];


Pssm-ID: 443330 [Multi-domain]  Cd Length: 331  Bit Score: 44.90  E-value: 3.06e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   1 MSLLELKDVSM----IYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMN-IVGCMDKG---TSGTVILDGEDISTLNS 72
Cdd:COG4170     1 MPLLDIRNLTIeidtPQGRVKAVDRVSLTLNEGEIRGLVGESGSGKSLIAKaICGITKDNwhvTADRFRWNGIDLLKLSP 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625  73 RNLTTIRRDKVGLVFQ--QFHLVPYLTALENIMiaqyyHSMPDE--------------AEALAALDRVGLKDRAKHL--- 133
Cdd:COG4170    81 RERRKIIGREIAMIFQepSSCLDPSAKIGDQLI-----EAIPSWtfkgkwwqrfkwrkKRAIELLHRVGIKDHKDIMnsy 155


                  ....*..
gi 2680999625 134 PSQLSGG 140
Cdd:COG4170   156 PHELTEG 162
cbiO PRK13645
energy-coupling factor transporter ATPase;
6-140 3.10e-06

energy-coupling factor transporter ATPase;


Pssm-ID: 184204 [Multi-domain]  Cd Length: 289  Bit Score: 45.00  E-value: 3.10e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   6 LKDVSMIYG-----SVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIV-GCMDKGTSGTVILDGEDISTLNSRNLTTIR 79
Cdd:PRK13645    9 LDNVSYTYAkktpfEFKALNNTSLTFKKNKVTCVIGTTGSGKSTMIQLTnGLIISETGQTIVGDYAIPANLKKIKEVKRL 88

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2680999625  80 RDKVGLVFQQFHLVPYLTALENIMIAQYYHSMPDEAEALAA----LDRVGL-KDRAKHLPSQLSGG 140
Cdd:PRK13645   89 RKEIGLVFQFPEYQLFQETIEKDIAFGPVNLGENKQEAYKKvpelLKLVQLpEDYVKRSPFELSGG 154
ABC_ABC_ChvD TIGR03719
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ...
 6-127 3.12e-06

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.


Pssm-ID: 274744 [Multi-domain]  Cd Length: 552  Bit Score: 45.31  E-value: 3.12e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   6 LKDVSMIYGSVKA-LQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDgEDIstlnsrnlttirrdKVG 84
Cdd:TIGR03719   7 MNRVSKVVPPKKEiLKDISLSFFPGAKIGVLGLNGAGKSTLLRIMAGVDKDFNGEARPQ-PGI--------------KVG 71

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 2680999625  85 LVFQQFHLVPYLTALENIMIAqyyhsMPDEAEALAALDRVGLK 127
Cdd:TIGR03719  72 YLPQEPQLDPTKTVRENVEEG-----VAEIKDALDRFNEISAK 109
sufC PRK09580
cysteine desulfurase ATPase component; Reviewed
 3-70 4.26e-06

cysteine desulfurase ATPase component; Reviewed


Pssm-ID: 181965 [Multi-domain]  Cd Length: 248  Bit Score: 44.40  E-value: 4.26e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   3 LLELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMD--KGTSGTVILDGEDISTL 70
Cdd:PRK09580    1 MLSIKDLHVSVEDKAILRGLNLEVRPGEVHAIMGPNGSGKSTLSATLAGREdyEVTGGTVEFKGKDLLEL 70
3a01205 TIGR00956
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
 19-107 8.69e-06

Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273362 [Multi-domain]  Cd Length: 1394  Bit Score: 43.94  E-value: 8.69e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   19 LQNINLTVERGEWLAIMGPSGSGKTTLMNivgCMDKGTSGTVILDGEDISTLNSRNLTTIRRdkVGLVFQQ-FHLvPYLT 97
Cdd:TIGR00956  779 LNNVDGWVKPGTLTALMGASGAGKTTLLN---VLAERVTTGVITGGDRLVNGRPLDSSFQRS--IGYVQQQdLHL-PTST 852

                           90
                   ....*....|
gi 2680999625   98 ALENIMIAQY 107
Cdd:TIGR00956  853 VRESLRFSAY 862
PRK13543 PRK13543
heme ABC exporter ATP-binding protein CcmA;
26-140 9.09e-06

heme ABC exporter ATP-binding protein CcmA;


Pssm-ID: 184129 [Multi-domain]  Cd Length: 214  Bit Score: 43.30  E-value: 9.09e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625  26 VERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNsrnlttiRRDKVGLVFQQFHLVPYLTALENIMIA 105
Cdd:PRK13543   34 VDAGEALLVQGDNGAGKTTLLRVLAGLLHVESGQIQIDGKTATRGD-------RSRFMAYLGHLPGLKADLSTLENLHFL 106

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 2680999625 106 QYYHSMPDEAEALAALDRVGLKDRAKHLPSQLSGG 140
Cdd:PRK13543  107 CGLHGRRAKQMPGSALAIVGLAGYEDTLVRQLSAG 141
MK0520 COG2401
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction ...
 19-140 1.01e-05

ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only];


Pssm-ID: 441957 [Multi-domain]  Cd Length: 222  Bit Score: 43.41  E-value: 1.01e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625  19 LQNINLTVERGEWLAIMGPSGSGKTTLMN-IVGCM-DKGTSGTVILDGEDIstlnSRNLTTIrrDKVGLVfqqfhlvpyl 96
Cdd:COG2401    46 LRDLNLEIEPGEIVLIVGASGSGKSTLLRlLAGALkGTPVAGCVDVPDNQF----GREASLI--DAIGRK---------- 109

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 2680999625  97 talenimiaqyyhsmPDEAEALAALDRVGLKD----RAKhlPSQLSGG 140
Cdd:COG2401   110 ---------------GDFKDAVELLNAVGLSDavlwLRR--FKELSTG 140
ABCC_CFTR1 cd03291
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The ...
 19-50 1.06e-05

ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The CFTR subfamily domain 1. The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits, or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.


Pssm-ID: 213258 [Multi-domain]  Cd Length: 282  Bit Score: 43.31  E-value: 1.06e-05
                          10        20        30
                  ....*....|....*....|....*....|...
gi 2680999625  19 LQNINLTVERGEWLAIMGPSGSGKTT-LMNIVG 50
Cdd:cd03291    53 LKNINLKIEKGEMLAITGSTGSGKTSlLMLILG 85
PRK03695 PRK03695
vitamin B12-transporter ATPase; Provisional
 4-140 1.98e-05

vitamin B12-transporter ATPase; Provisional


Pssm-ID: 235150 [Multi-domain]  Cd Length: 248  Bit Score: 42.61  E-value: 1.98e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   4 LELKDVSMiygsVKALQNINLTVERGEWLAIMGPSGSGKTTLMnivGCMdKGT---SGTVILDGEDISTLNSRNLTTIRr 80
Cdd:PRK03695    1 MQLNDVAV----STRLGPLSAEVRAGEILHLVGPNGAGKSTLL---ARM-AGLlpgSGSIQFAGQPLEAWSAAELARHR- 71

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2680999625  81 dkvGLVFQQ---------FHlvpYLtalenimiAQYYHSMPDEAEALAALDRV----GLKDRAKHLPSQLSGG 140
Cdd:PRK03695   72 ---AYLSQQqtppfampvFQ---YL--------TLHQPDKTRTEAVASALNEVaealGLDDKLGRSVNQLSGG 130
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
5-68 2.05e-05

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 42.80  E-value: 2.05e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2680999625   5 ELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDIS 68
Cdd:NF033858    3 RLEGVSHRYGKTVALDDVSLDIPAGCMVGLIGPDGVGKSSLLSLIAGARKIQQGRVEVLGGDMA 66
PRK15112 PRK15112
peptide ABC transporter ATP-binding protein SapF;
2-68 3.06e-05

peptide ABC transporter ATP-binding protein SapF;


Pssm-ID: 185067 [Multi-domain]  Cd Length: 267  Bit Score: 42.08  E-value: 3.06e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2680999625   2 SLLELKDVSMIY---------GSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDIS 68
Cdd:PRK15112    3 TLLEVRNLSKTFryrtgwfrrQTVEAVKPLSFTLREGQTLAIIGENGSGKSTLAKMLAGMIEPTSGELLIDDHPLH 78
PRK13546 PRK13546
teichoic acids export ABC transporter ATP-binding subunit TagH;
18-65 3.23e-05

teichoic acids export ABC transporter ATP-binding subunit TagH;


Pssm-ID: 184131 [Multi-domain]  Cd Length: 264  Bit Score: 42.11  E-value: 3.23e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 2680999625  18 ALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGE 65
Cdd:PRK13546   39 ALDDISLKAYEGDVIGLVGINGSGKSTLSNIIGGSLSPTVGKVDRNGE 86
MRP_assoc_pro TIGR00957
multi drug resistance-associated protein (MRP); This model describes multi drug ...
 19-137 3.50e-05

multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]


Pssm-ID: 188098 [Multi-domain]  Cd Length: 1522  Bit Score: 42.24  E-value: 3.50e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   19 LQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNSRNLttirRDKVGLVFQQfhlvPYLTA 98
Cdd:TIGR00957 1302 LRHINVTIHGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGLNIAKIGLHDL----RFKITIIPQD----PVLFS 1373

                           90       100       110
                   ....*....|....*....|....*....|....*....
gi 2680999625   99 LENIMIAQYYHSMPDEaEALAALDRVGLKDRAKHLPSQL 137
Cdd:TIGR00957 1374 GSLRMNLDPFSQYSDE-EVWWALELAHLKTFVSALPDKL 1411
PRK11819 PRK11819
putative ABC transporter ATP-binding protein; Reviewed
 6-123 4.05e-05

putative ABC transporter ATP-binding protein; Reviewed


Pssm-ID: 236992 [Multi-domain]  Cd Length: 556  Bit Score: 42.03  E-value: 4.05e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   6 LKDVSMIYGSVKA-LQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDgEDIstlnsrnlttirrdKVG 84
Cdd:PRK11819    9 MNRVSKVVPPKKQiLKDISLSFFPGAKIGVLGLNGAGKSTLLRIMAGVDKEFEGEARPA-PGI--------------KVG 73

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 2680999625  85 LVFQQFHLVPYLTALENIMIAQyyhsmpdeAEALAALDR 123
Cdd:PRK11819   74 YLPQEPQLDPEKTVRENVEEGV--------AEVKAALDR 104
CFTR_protein TIGR01271
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ...
 19-50 4.21e-05

cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]


Pssm-ID: 273530 [Multi-domain]  Cd Length: 1490  Bit Score: 42.20  E-value: 4.21e-05
                           10        20        30
                   ....*....|....*....|....*....|...
gi 2680999625   19 LQNINLTVERGEWLAIMGPSGSGKTT-LMNIVG 50
Cdd:TIGR01271  442 LKNISFKLEKGQLLAVAGSTGSGKSSlLMMIMG 474
ABC_ABC_ChvD TIGR03719
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ...
 4-65 4.22e-05

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.


Pssm-ID: 274744 [Multi-domain]  Cd Length: 552  Bit Score: 41.84  E-value: 4.22e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2680999625   4 LELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILdGE 65
Cdd:TIGR03719 323 IEAENLTKAFGDKLLIDDLSFKLPPGGIVGVIGPNGAGKSTLFRMITGQEQPDSGTIEI-GE 383
tagH PRK13545
teichoic acids export protein ATP-binding subunit; Provisional
 18-64 5.23e-05

teichoic acids export protein ATP-binding subunit; Provisional


Pssm-ID: 184130 [Multi-domain]  Cd Length: 549  Bit Score: 41.80  E-value: 5.23e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 2680999625  18 ALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDG 64
Cdd:PRK13545   39 ALNNISFEVPEGEIVGIIGLNGSGKSTLSNLIAGVTMPNKGTVDIKG 85
PRK10762 PRK10762
D-ribose transporter ATP binding protein; Provisional
 4-69 6.84e-05

D-ribose transporter ATP binding protein; Provisional


Pssm-ID: 236755 [Multi-domain]  Cd Length: 501  Bit Score: 41.14  E-value: 6.84e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2680999625   4 LELKDVSmiyGSvkALQNINLTVERGEWLAIMGPSGSGKTTLMNIV-GCMDKgTSGTVILDGEDIST 69
Cdd:PRK10762  258 LKVDNLS---GP--GVNDVSFTLRKGEILGVSGLMGAGRTELMKVLyGALPR-TSGYVTLDGHEVVT 318
PRK13549 PRK13549
xylose transporter ATP-binding subunit; Provisional
 16-140 8.57e-05

xylose transporter ATP-binding subunit; Provisional


Pssm-ID: 184134 [Multi-domain]  Cd Length: 506  Bit Score: 41.07  E-value: 8.57e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625  16 VKALQNINLTVERGEWLAIMGPSGSGKTTLMN-IVGCMDKGTSGTVILDGEDISTLNSRNltTIRRdkvGLVF-----QQ 89
Cdd:PRK13549  275 IKRVDDVSFSLRRGEILGIAGLVGAGRTELVQcLFGAYPGRWEGEIFIDGKPVKIRNPQQ--AIAQ---GIAMvpedrKR 349

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625  90 FHLVPYLTALENIMIA---QYYH-SMPDEAE----ALAALDRVGLKDRAKHLP-SQLSGG 140
Cdd:PRK13549  350 DGIVPVMGVGKNITLAaldRFTGgSRIDDAAelktILESIQRLKVKTASPELAiARLSGG 409
PRK14258 PRK14258
phosphate ABC transporter ATP-binding protein; Provisional
 4-102 1.07e-04

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 184593 [Multi-domain]  Cd Length: 261  Bit Score: 40.41  E-value: 1.07e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   4 LELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTS-----GTVILDGEDISTlNSRNLTTI 78
Cdd:PRK14258    8 IKVNNLSFYYDTQKILEGVSMEIYQSKVTAIIGPSGCGKSTFLKCLNRMNELESevrveGRVEFFNQNIYE-RRVNLNRL 86

                          90       100
                  ....*....|....*....|....
gi 2680999625  79 RRdKVGLVFQQFHLVPyLTALENI 102
Cdd:PRK14258   87 RR-QVSMVHPKPNLFP-MSVYDNV 108
GguA NF040905
sugar ABC transporter ATP-binding protein;
17-71 1.16e-04

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 40.54  E-value: 1.16e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2680999625  17 KALQNINLTVERGEWLAIMGPSGSGKTTL-MNIVG-CMDKGTSGTVILDGEDISTLN 71
Cdd:NF040905  274 KVVDDVSLNVRRGEIVGIAGLMGAGRTELaMSVFGrSYGRNISGTVFKDGKEVDVST 330
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 32-93 1.32e-04

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 39.66  E-value: 1.32e-04
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2680999625   32 LAIMGPSGSGKTTLMN-IVGCMDKGTSGTVILDGEDISTLNSRNLTTIRRDKVGLVFQQFHLV 93
Cdd:smart00382   5 ILIVGPPGSGKTTLARaLARELGPPGGGVIYIDGEDILEEVLDQLLLIIVGGKKASGSGELRL 67
PRK13540 PRK13540
cytochrome c biogenesis protein CcmA; Provisional
 3-125 1.37e-04

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 184127 [Multi-domain]  Cd Length: 200  Bit Score: 39.93  E-value: 1.37e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   3 LLELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDIstlnSRNLTTIRRdK 82
Cdd:PRK13540    1 MLDVIELDFDYHDQPLLQQISFHLPAGGLLHLKGSNGAGKTTLLKLIAGLLNPEKGEILFERQSI----KKDLCTYQK-Q 75

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 2680999625  83 VGLVFQQFHLVPYLTALENIMIAQYYHSMPDEAEALAALDRVG 125
Cdd:PRK13540   76 LCFVGHRSGINPYLTLRENCLYDIHFSPGAVGITELCRLFSLE 118
PRK10789 PRK10789
SmdA family multidrug ABC transporter permease/ATP-binding protein;
18-49 1.67e-04

SmdA family multidrug ABC transporter permease/ATP-binding protein;


Pssm-ID: 182732 [Multi-domain]  Cd Length: 569  Bit Score: 40.08  E-value: 1.67e-04
                          10        20        30
                  ....*....|....*....|....*....|..
gi 2680999625  18 ALQNINLTVERGEWLAIMGPSGSGKTTLMNIV 49
Cdd:PRK10789  330 ALENVNFTLKPGQMLGICGPTGSGKSTLLSLI 361
PTZ00243 PTZ00243
ABC transporter; Provisional
 4-129 1.73e-04

ABC transporter; Provisional


Pssm-ID: 240327 [Multi-domain]  Cd Length: 1560  Bit Score: 40.15  E-value: 1.73e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625    4 LELKDVSMIY--GSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNSRNLttiRRd 81
Cdd:PTZ00243  1309 LVFEGVQMRYreGLPLVLRGVSFRIAPREKVGIVGRTGSGKSTLLLTFMRMVEVCGGEIRVNGREIGAYGLREL---RR- 1384

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|..
gi 2680999625   82 kvglvfqQFHLVPYLTALENIMIAQ----YYHSMPdeAEALAALDRVGLKDR 129
Cdd:PTZ00243  1385 -------QFSMIPQDPVLFDGTVRQnvdpFLEASS--AEVWAALELVGLRER 1427
PRK11147 PRK11147
ABC transporter ATPase component; Reviewed
 5-60 2.10e-04

ABC transporter ATPase component; Reviewed


Pssm-ID: 236861 [Multi-domain]  Cd Length: 635  Bit Score: 39.93  E-value: 2.10e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2680999625   5 ELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTV 60
Cdd:PRK11147  321 EMENVNYQIDGKQLVKDFSAQVQRGDKIALIGPNGCGKTTLLKLMLGQLQADSGRI 376
hmuV PRK13547
heme ABC transporter ATP-binding protein;
19-140 3.87e-04

heme ABC transporter ATP-binding protein;


Pssm-ID: 184132 [Multi-domain]  Cd Length: 272  Bit Score: 39.04  E-value: 3.87e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625  19 LQNINLTVERGEWLAIMGPSGSGKTTLMNIV------GCMDKGT--SGTVILDGEDISTLNSRNLTTIRrdkvGLVFQQF 90
Cdd:PRK13547   17 LRDLSLRIEPGRVTALLGRNGAGKSTLLKALagdltgGGAPRGArvTGDVTLNGEPLAAIDAPRLARLR----AVLPQAA 92

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2680999625  91 HLVPYLTALENIMIAQYYH-------SMPDEAEALAALDRVGLKDRAKHLPSQLSGG 140
Cdd:PRK13547   93 QPAFAFSAREIVLLGRYPHarragalTHRDGEIAWQALALAGATALVGRDVTTLSGG 149
araG PRK11288
L-arabinose ABC transporter ATP-binding protein AraG;
22-68 4.79e-04

L-arabinose ABC transporter ATP-binding protein AraG;


Pssm-ID: 183077 [Multi-domain]  Cd Length: 501  Bit Score: 38.74  E-value: 4.79e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 2680999625  22 INLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDIS 68
Cdd:PRK11288  272 ISFSVRAGEIVGLFGLVGAGRSELMKLLYGATRRTAGQVYLDGKPID 318
uvra TIGR00630
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of ...
 19-47 4.81e-04

excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of proteins of which all members for which functions are known except the UvrA proteins are involved in the transport of material through membranes. UvrA orthologs are involved in the recognition of DNA damage as a step in nucleotide excision repair. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273184 [Multi-domain]  Cd Length: 925  Bit Score: 38.84  E-value: 4.81e-04
                          10        20
                  ....*....|....*....|....*....
gi 2680999625  19 LQNINLTVERGEWLAIMGPSGSGKTTLMN 47
Cdd:TIGR00630 624 LKNITVSIPLGLFTCITGVSGSGKSTLIN 652
PLN03130 PLN03130
ABC transporter C family member; Provisional
 19-64 8.03e-04

ABC transporter C family member; Provisional


Pssm-ID: 215595 [Multi-domain]  Cd Length: 1622  Bit Score: 38.18  E-value: 8.03e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*..
gi 2680999625   19 LQNINLTVERGEWLAIMGPSGSGKTTLMN-IVGCMDKGTSGTVILDG 64
Cdd:PLN03130   633 LSNINLDVPVGSLVAIVGSTGEGKTSLISaMLGELPPRSDASVVIRG 679
xylG TIGR02633
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ...
 16-140 9.91e-04

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 131681 [Multi-domain]  Cd Length: 500  Bit Score: 37.88  E-value: 9.91e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625  16 VKALQNINLTVERGEWLAIMGPSGSGKTTLMN-IVGCMDKGTSGTVILDGEDISTlnsRNLTTIRRDKVGLV---FQQFH 91
Cdd:TIGR02633 273 RKRVDDVSFSLRRGEILGVAGLVGAGRTELVQaLFGAYPGKFEGNVFINGKPVDI---RNPAQAIRAGIAMVpedRKRHG 349

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2680999625  92 LVPYLTALENIMIA---QYYHSMPDEAEA-----LAALDRVGLKDRAKHLP-SQLSGG 140
Cdd:TIGR02633 350 IVPILGVGKNITLSvlkSFCFKMRIDAAAelqiiGSAIQRLKVKTASPFLPiGRLSGG 407
Rli1 COG1245
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...
 16-68 1.02e-03

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440858 [Multi-domain]  Cd Length: 592  Bit Score: 37.84  E-value: 1.02e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2680999625  16 VKALQNINLTVE-----RGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDgEDIS 68
Cdd:COG1245   348 TKSYGGFSLEVEggeirEGEVLGIVGPNGIGKTTFAKILAGVLKPDEGEVDED-LKIS 404
PRK15056 PRK15056
manganese/iron ABC transporter ATP-binding protein;
18-140 1.17e-03

manganese/iron ABC transporter ATP-binding protein;


Pssm-ID: 185016 [Multi-domain]  Cd Length: 272  Bit Score: 37.55  E-value: 1.17e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625  18 ALQNINLTVERGEWLAIMGPSGSGKTTLMnivgcmdKGTSGTVILDGEDISTLNSRNLTTIRRDKVGLVFQQFHL---VP 94
Cdd:PRK15056   22 ALRDASFTVPGGSIAALVGVNGSGKSTLF-------KALMGFVRLASGKISILGQPTRQALQKNLVAYVPQSEEVdwsFP 94

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2680999625  95 YLTAlENIMIAQYYH-------SMPDEAEALAALDRVGLKDRAKHLPSQLSGG 140
Cdd:PRK15056   95 VLVE-DVVMMGRYGHmgwlrraKKRDRQIVTAALARVDMVEFRHRQIGELSGG 146
PRK15093 PRK15093
peptide ABC transporter ATP-binding protein SapD;
1-89 1.32e-03

peptide ABC transporter ATP-binding protein SapD;


Pssm-ID: 185049 [Multi-domain]  Cd Length: 330  Bit Score: 37.47  E-value: 1.32e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   1 MSLLELKDVSMIY----GSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKG----TSGTVILDGEDISTLNS 72
Cdd:PRK15093    1 MPLLDIRNLTIEFktsdGWVKAVDRVSMTLTEGEIRGLVGESGSGKSLIAKAICGVTKDnwrvTADRMRFDDIDLLRLSP 80

                          90
                  ....*....|....*..
gi 2680999625  73 RNLTTIRRDKVGLVFQQ 89
Cdd:PRK15093   81 RERRKLVGHNVSMIFQE 97
ABC_RNaseL_inhibitor_domain2 cd03237
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...
 15-68 1.36e-03

The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity of more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213204 [Multi-domain]  Cd Length: 246  Bit Score: 37.39  E-value: 1.36e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2680999625  15 SVKALQNINLTVE-----RGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDIS 68
Cdd:cd03237     6 MKKTLGEFTLEVEggsisESEVIGILGPNGIGKTTFIKMLAGVLKPDEGDIEIELDTVS 64
UvrA COG0178
Excinuclease UvrABC ATPase subunit [Replication, recombination and repair];
19-45 1.86e-03

Excinuclease UvrABC ATPase subunit [Replication, recombination and repair];


Pssm-ID: 439948 [Multi-domain]  Cd Length: 941  Bit Score: 37.31  E-value: 1.86e-03
                          10        20
                  ....*....|....*....|....*..
gi 2680999625  19 LQNINLTVERGEWLAIMGPSGSGKTTL 45
Cdd:COG0178    16 LKNIDVDIPRNKLVVITGLSGSGKSSL 42
PRK15439 PRK15439
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
 21-87 2.06e-03

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional


Pssm-ID: 185336 [Multi-domain]  Cd Length: 510  Bit Score: 36.95  E-value: 2.06e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2680999625  21 NINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDIStlnsrNLTTIRRDKVGLVF 87
Cdd:PRK15439  281 NISLEVRAGEILGLAGVVGAGRTELAETLYGLRPARGGRIMLNGKEIN-----ALSTAQRLARGLVY 342
PRK11819 PRK11819
putative ABC transporter ATP-binding protein; Reviewed
 4-65 2.60e-03

putative ABC transporter ATP-binding protein; Reviewed


Pssm-ID: 236992 [Multi-domain]  Cd Length: 556  Bit Score: 36.64  E-value: 2.60e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2680999625   4 LELKDVSMIYGSVKALQNINLTVERGEWLAIMGPSGSGKTTLMN-IVGcMDKGTSGTVILdGE 65
Cdd:PRK11819  325 IEAENLSKSFGDRLLIDDLSFSLPPGGIVGIIGPNGAGKSTLFKmITG-QEQPDSGTIKI-GE 385
uvrA PRK00349
excinuclease ABC subunit UvrA;
19-47 2.85e-03

excinuclease ABC subunit UvrA;


Pssm-ID: 234734 [Multi-domain]  Cd Length: 943  Bit Score: 36.59  E-value: 2.85e-03
                          10        20
                  ....*....|....*....|....*....
gi 2680999625  19 LQNINLTVERGEWLAIMGPSGSGKTTLMN 47
Cdd:PRK00349  625 LKNVDVEIPLGKFTCVTGVSGSGKSTLIN 653
CFTR_protein TIGR01271
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ...
 19-137 2.87e-03

cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]


Pssm-ID: 273530 [Multi-domain]  Cd Length: 1490  Bit Score: 36.81  E-value: 2.87e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   19 LQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMdKGTSGTVILDGediSTLNSRNLTTIRRdKVGLVFQQF-------- 90
Cdd:TIGR01271 1235 LQDLSFSVEGGQRVGLLGRTGSGKSTLLSALLRL-LSTEGEIQIDG---VSWNSVTLQTWRK-AFGVIPQKVfifsgtfr 1309

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*...
gi 2680999625   91 -HLVPYltalenimiAQYyhsmPDEaEALAALDRVGLKDRAKHLPSQL 137
Cdd:TIGR01271 1310 kNLDPY---------EQW----SDE-EIWKVAEEVGLKSVIEQFPDKL 1343
ABC_UvrA_II cd03271
ATP-binding cassette domain II of the excision repair protein UvrA; Nucleotide excision repair ...
 19-47 3.44e-03

ATP-binding cassette domain II of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins and UvrB having one ATP binding site that is structurally related to that of helicases.


Pssm-ID: 213238 [Multi-domain]  Cd Length: 261  Bit Score: 36.05  E-value: 3.44e-03
                          10        20
                  ....*....|....*....|....*....
gi 2680999625  19 LQNINLTVERGEWLAIMGPSGSGKTTLMN 47
Cdd:cd03271    11 LKNIDVDIPLGVLTCVTGVSGSGKSSLIN 39
PhnN COG3709
Ribose 1,5-bisphosphate kinase PhnN [Carbohydrate transport and metabolism];
27-47 3.81e-03

Ribose 1,5-bisphosphate kinase PhnN [Carbohydrate transport and metabolism];


Pssm-ID: 442923  Cd Length: 188  Bit Score: 35.55  E-value: 3.81e-03
                          10        20
                  ....*....|....*....|.
gi 2680999625  27 ERGEWLAIMGPSGSGKTTLMN 47
Cdd:COG3709     3 GPGRLIYVVGPSGAGKDSLLA 23
PLN03130 PLN03130
ABC transporter C family member; Provisional
 4-128 3.85e-03

ABC transporter C family member; Provisional


Pssm-ID: 215595 [Multi-domain]  Cd Length: 1622  Bit Score: 36.25  E-value: 3.85e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625    4 LELKDVSMIYGS--VKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDGEDISTLNSRNLttirRD 81
Cdd:PLN03130  1238 IKFEDVVLRYRPelPPVLHGLSFEISPSEKVGIVGRTGAGKSSMLNALFRIVELERGRILIDGCDISKFGLMDL----RK 1313

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 2680999625   82 KVGLVFQ---------QFHLVPYltalenimiaqyyhSMPDEAEALAALDRVGLKD 128
Cdd:PLN03130  1314 VLGIIPQapvlfsgtvRFNLDPF--------------NEHNDADLWESLERAHLKD 1355
ABC_UvrA_I cd03270
ATP-binding cassette domain I of the excision repair protein UvrA; Nucleotide excision repair ...
 19-45 4.45e-03

ATP-binding cassette domain I of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.


Pssm-ID: 213237 [Multi-domain]  Cd Length: 226  Bit Score: 35.70  E-value: 4.45e-03
                          10        20
                  ....*....|....*....|....*..
gi 2680999625  19 LQNINLTVERGEWLAIMGPSGSGKTTL 45
Cdd:cd03270    11 LKNVDVDIPRNKLVVITGVSGSGKSSL 37
PRK13409 PRK13409
ribosome biogenesis/translation initiation ATPase RLI;
16-68 5.44e-03

ribosome biogenesis/translation initiation ATPase RLI;


Pssm-ID: 184037 [Multi-domain]  Cd Length: 590  Bit Score: 35.55  E-value: 5.44e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2680999625  16 VKALQNINLTVE-----RGEWLAIMGPSGSGKTTLMNIVGCMDKGTSGTVILDgEDIS 68
Cdd:PRK13409  347 TKKLGDFSLEVEggeiyEGEVIGIVGPNGIGKTTFAKLLAGVLKPDEGEVDPE-LKIS 403
PTZ00265 PTZ00265
multidrug resistance protein (mdr1); Provisional
 4-49 5.59e-03

multidrug resistance protein (mdr1); Provisional


Pssm-ID: 240339 [Multi-domain]  Cd Length: 1466  Bit Score: 35.78  E-value: 5.59e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 2680999625    4 LELKDVSMIYGS---VKALQNINLTVERGEWLAIMGPSGSGKTTLMNIV 49
Cdd:PTZ00265  1166 IEIMDVNFRYISrpnVPIYKDLTFSCDSKKTTAIVGETGSGKSTVMSLL 1214
VirB4_CagE TIGR00929
type IV secretion/conjugal transfer ATPase, VirB4 family; Type IV secretion systems are found ...
 33-52 7.84e-03

type IV secretion/conjugal transfer ATPase, VirB4 family; Type IV secretion systems are found in Gram-negative pathogens. They export proteins, DNA, or complexes in different systems and are related to plasmid conjugation systems. This model represents related ATPases that include VirB4 in Agrobacterium tumefaciens (DNA export) CagE in Helicobacter pylori (protein export) and plasmid TraB (conjugation).


Pssm-ID: 273346 [Multi-domain]  Cd Length: 785  Bit Score: 35.37  E-value: 7.84e-03
                          10        20
                  ....*....|....*....|
gi 2680999625  33 AIMGPSGSGKTTLMNIVGCM 52
Cdd:TIGR00929 438 LIFGPTGSGKTTLLNFLLAQ 457
ABCC_CFTR2 cd03289
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator ...
 4-137 7.87e-03

ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.


Pssm-ID: 213256 [Multi-domain]  Cd Length: 275  Bit Score: 35.22  E-value: 7.87e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2680999625   4 LELKDVSMIY--GSVKALQNINLTVERGEWLAIMGPSGSGKTTLMNIVGCMdKGTSGTVILDGediSTLNSRNLTTIRRd 81
Cdd:cd03289     3 MTVKDLTAKYteGGNAVLENISFSISPGQRVGLLGRTGSGKSTLLSAFLRL-LNTEGDIQIDG---VSWNSVPLQKWRK- 77

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2680999625  82 KVGLVFQQFHLV--PYLTALENimiaqyYHSMPDEaEALAALDRVGLKDRAKHLPSQL 137
Cdd:cd03289    78 AFGVIPQKVFIFsgTFRKNLDP------YGKWSDE-EIWKVAEEVGLKSVIEQFPGQL 128
uvra TIGR00630
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of ...
 19-45 8.66e-03

excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of proteins of which all members for which functions are known except the UvrA proteins are involved in the transport of material through membranes. UvrA orthologs are involved in the recognition of DNA damage as a step in nucleotide excision repair. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273184 [Multi-domain]  Cd Length: 925  Bit Score: 35.37  E-value: 8.66e-03
                          10        20
                  ....*....|....*....|....*..
gi 2680999625  19 LQNINLTVERGEWLAIMGPSGSGKTTL 45
Cdd:TIGR00630  12 LKNIDVEIPRDKLVVITGLSGSGKSSL 38
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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