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Conserved domains on  [gi|2700818062|ref|WP_337510798|]
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MULTISPECIES: YbaK/EbsC family protein [Acidaminococcus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ProX super family cl43942
Predicted aminoacyl-tRNA deacylase, YbaK-like aminoacyl-tRNA editing domain [General function ...
 4-118 5.10e-11

Predicted aminoacyl-tRNA deacylase, YbaK-like aminoacyl-tRNA editing domain [General function prediction only];


The actual alignment was detected with superfamily member COG3760:

Pssm-ID: 442974  Cd Length: 162  Bit Score: 56.68  E-value: 5.10e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2700818062   4 NKEIQIYGPLQKLKILYEGFPHAPIVTLDEDLALAETMKAVVVKDLF---------------GEAPkkklfflfflaege 68
Cdd:COG3760     2 LTEQELYALLDELGIPYETVEHPPVFTVEEAEALRGDLPGAHTKNLFlrdkkgtrfylvvvpEDKR-------------- 67

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 2700818062  69 fFTGKALQETLGAGHLTFGDKKALSRLLCCEKGAVSALELLFDTKQAVTL 118
Cdd:COG3760    68 -VDLKALSKQLGSGRLSFASPERLEEYLGVTPGSVTPFGLINDTENRVTV 116
 
Name Accession Description Interval E-value
ProX COG3760
Predicted aminoacyl-tRNA deacylase, YbaK-like aminoacyl-tRNA editing domain [General function ...
 4-118 5.10e-11

Predicted aminoacyl-tRNA deacylase, YbaK-like aminoacyl-tRNA editing domain [General function prediction only];


Pssm-ID: 442974  Cd Length: 162  Bit Score: 56.68  E-value: 5.10e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2700818062   4 NKEIQIYGPLQKLKILYEGFPHAPIVTLDEDLALAETMKAVVVKDLF---------------GEAPkkklfflfflaege 68
Cdd:COG3760     2 LTEQELYALLDELGIPYETVEHPPVFTVEEAEALRGDLPGAHTKNLFlrdkkgtrfylvvvpEDKR-------------- 67

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 2700818062  69 fFTGKALQETLGAGHLTFGDKKALSRLLCCEKGAVSALELLFDTKQAVTL 118
Cdd:COG3760    68 -VDLKALSKQLGSGRLSFASPERLEEYLGVTPGSVTPFGLINDTENRVTV 116
PrdX_deacylase cd04335
This CD includes bacterial (Agrobacterium tumefaciens and Caulobacter crescentus ProX, and ...
 6-118 1.18e-10

This CD includes bacterial (Agrobacterium tumefaciens and Caulobacter crescentus ProX, and Clostridium sticklandii PrdX) and eukaryotic (Plasmodium falciparum N-terminal ProRS editing domain) sequences. The C. sticklandii PrdX protein, a homolog of the YbaK and ProX proteins, and the prolyl-tRNA synthetase-editing domain (ProRS-INS), specifically hydrolyzes Ala-tRNA(Pro). In this CD, many of the eukaryotic editing domains are N-terminal and cis-acting, expressed from a multidomain ProRS, however, similar to the bacterial PrdX, the mammalian, amphibian, and echinoderm PrdX-like proteins are trans-acting, single-domain proteins.


Pssm-ID: 239827  Cd Length: 156  Bit Score: 55.60  E-value: 1.18e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2700818062   6 EIQIYGPLQKLKILYEGFPHAPIVTLDEDLALAETMKAVVVKDLFgeapkkklfflFFLAEGEFF----------TGKAL 75
Cdd:cd04335     1 EDELLALLDELGIAYETVEHPPVFTVEEADEVLGELPGAHTKNLF-----------LKDKKGRLYlvtalhdkkvDLKAL 69

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 2700818062  76 QETLGAGHLTFGDKKALSRLLCCEKGAVSALELLFDTKQAVTL 118
Cdd:cd04335    70 SKQLGASRLSFASEERLEEKLGVTPGSVTPFALINDKENDVQV 112
 
Name Accession Description Interval E-value
ProX COG3760
Predicted aminoacyl-tRNA deacylase, YbaK-like aminoacyl-tRNA editing domain [General function ...
 4-118 5.10e-11

Predicted aminoacyl-tRNA deacylase, YbaK-like aminoacyl-tRNA editing domain [General function prediction only];


Pssm-ID: 442974  Cd Length: 162  Bit Score: 56.68  E-value: 5.10e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2700818062   4 NKEIQIYGPLQKLKILYEGFPHAPIVTLDEDLALAETMKAVVVKDLF---------------GEAPkkklfflfflaege 68
Cdd:COG3760     2 LTEQELYALLDELGIPYETVEHPPVFTVEEAEALRGDLPGAHTKNLFlrdkkgtrfylvvvpEDKR-------------- 67

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 2700818062  69 fFTGKALQETLGAGHLTFGDKKALSRLLCCEKGAVSALELLFDTKQAVTL 118
Cdd:COG3760    68 -VDLKALSKQLGSGRLSFASPERLEEYLGVTPGSVTPFGLINDTENRVTV 116
PrdX_deacylase cd04335
This CD includes bacterial (Agrobacterium tumefaciens and Caulobacter crescentus ProX, and ...
 6-118 1.18e-10

This CD includes bacterial (Agrobacterium tumefaciens and Caulobacter crescentus ProX, and Clostridium sticklandii PrdX) and eukaryotic (Plasmodium falciparum N-terminal ProRS editing domain) sequences. The C. sticklandii PrdX protein, a homolog of the YbaK and ProX proteins, and the prolyl-tRNA synthetase-editing domain (ProRS-INS), specifically hydrolyzes Ala-tRNA(Pro). In this CD, many of the eukaryotic editing domains are N-terminal and cis-acting, expressed from a multidomain ProRS, however, similar to the bacterial PrdX, the mammalian, amphibian, and echinoderm PrdX-like proteins are trans-acting, single-domain proteins.


Pssm-ID: 239827  Cd Length: 156  Bit Score: 55.60  E-value: 1.18e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2700818062   6 EIQIYGPLQKLKILYEGFPHAPIVTLDEDLALAETMKAVVVKDLFgeapkkklfflFFLAEGEFF----------TGKAL 75
Cdd:cd04335     1 EDELLALLDELGIAYETVEHPPVFTVEEADEVLGELPGAHTKNLF-----------LKDKKGRLYlvtalhdkkvDLKAL 69

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 2700818062  76 QETLGAGHLTFGDKKALSRLLCCEKGAVSALELLFDTKQAVTL 118
Cdd:cd04335    70 SKQLGASRLSFASEERLEEKLGVTPGSVTPFALINDKENDVQV 112
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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