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Conserved domains on  [gi|2710808042|ref|WP_338477036|]
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IS3 family transposase [Wolbachia endosymbiont (group A) of Nomada hirtipes]

Protein Classification

transposase family protein( domain architecture ID 1750059)

transposase family protein might bind to the end of a transposon and catalyze the movement of the transposon to another part of the genome by a cut and paste mechanism or a replicative transposition mechanism

Gene Ontology:  GO:0003677|GO:0006313
PubMed:  11774877

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
transpos_IS3 super family cl41295
IS3 family transposase;
15-98 7.77e-22

IS3 family transposase;


The actual alignment was detected with superfamily member NF033516:

Pssm-ID: 468052 [Multi-domain]  Cd Length: 369  Bit Score: 87.24  E-value: 7.77e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2710808042  15 VGFSASGYYKWTTRKISSRESANKELLEAIQKIYQVSKCRYGAPKIHAELKALGKSCNLKTVQSIMQKNDIRAILKRKFI 94
Cdd:NF033516  110 LGVSRSTYYYWRKRPPSRRAPDDAELRARIREIFEESRGRYGYRRITALLRREGIRVNHKRVYRLMRELGLLARRRRKRR 189


                  ....
gi 2710808042  95 ALST 98
Cdd:NF033516  190 PYTT 193
 
Name Accession Description Interval E-value
transpos_IS3 NF033516
IS3 family transposase;
15-98 7.77e-22

IS3 family transposase;


Pssm-ID: 468052 [Multi-domain]  Cd Length: 369  Bit Score: 87.24  E-value: 7.77e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2710808042  15 VGFSASGYYKWTTRKISSRESANKELLEAIQKIYQVSKCRYGAPKIHAELKALGKSCNLKTVQSIMQKNDIRAILKRKFI 94
Cdd:NF033516  110 LGVSRSTYYYWRKRPPSRRAPDDAELRARIREIFEESRGRYGYRRITALLRREGIRVNHKRVYRLMRELGLLARRRRKRR 189


                  ....
gi 2710808042  95 ALST 98
Cdd:NF033516  190 PYTT 193
HTH_21 pfam13276
HTH-like domain; This domain contains a predicted helix-turn-helix suggesting a DNA-binding ...
 35-93 7.81e-14

HTH-like domain; This domain contains a predicted helix-turn-helix suggesting a DNA-binding function.


Pssm-ID: 463824 [Multi-domain]  Cd Length: 60  Bit Score: 60.28  E-value: 7.81e-14
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2710808042  35 SANKELLEAIQKIYQVSKCRYGAPKIHAELKALGK-SCNLKTVQSIMQKNDIRAILKRKF 93
Cdd:pfam13276   1 ELEDELLEAIREIFEESRGTYGYRRITAELRREGGiRVNRKRVARLMRELGLRARRRRKR 60
Tra5 COG2801
Transposase InsO and inactivated derivatives [Mobilome: prophages, transposons];
18-93 3.19e-12

Transposase InsO and inactivated derivatives [Mobilome: prophages, transposons];


Pssm-ID: 442053 [Multi-domain]  Cd Length: 309  Bit Score: 60.55  E-value: 3.19e-12
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2710808042  18 SASGYYKWTTRKISSRESANKELLEAIQKIYQVSKcRYGAPKIHAELKALGKSCNLKTVQSIMQKNDIRAILKRKF 93
Cdd:COG2801    51 ARSRRRRRLRRPRSYRADEDAELLERIKEIFAESP-RYGYRRITAELRREGIAVNRKRVRRLMRELGLQARRRRKK 125
PHA02517 PHA02517
putative transposase OrfB; Reviewed
 16-97 1.90e-07

putative transposase OrfB; Reviewed


Pssm-ID: 222853 [Multi-domain]  Cd Length: 277  Bit Score: 47.17  E-value: 1.90e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2710808042  16 GFSASGYYKWTTR-----KISSRESANKELLEAIQKIYQVSKCRYGAPKIHAELKALGKSCNLKTVQSIMQKNDIRAILK 90
Cdd:PHA02517    2 GIAPSTYYRCQQQrhhpdKRRARAQHDDWLKSEILRVYDENHQVYGVRKVWRQLNREGIRVARCTVGRLMKELGLAGVLR 81


                  ....*..
gi 2710808042  91 RKFIALS 97
Cdd:PHA02517   82 GKKVRTT 88
 
Name Accession Description Interval E-value
transpos_IS3 NF033516
IS3 family transposase;
15-98 7.77e-22

IS3 family transposase;


Pssm-ID: 468052 [Multi-domain]  Cd Length: 369  Bit Score: 87.24  E-value: 7.77e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2710808042  15 VGFSASGYYKWTTRKISSRESANKELLEAIQKIYQVSKCRYGAPKIHAELKALGKSCNLKTVQSIMQKNDIRAILKRKFI 94
Cdd:NF033516  110 LGVSRSTYYYWRKRPPSRRAPDDAELRARIREIFEESRGRYGYRRITALLRREGIRVNHKRVYRLMRELGLLARRRRKRR 189


                  ....
gi 2710808042  95 ALST 98
Cdd:NF033516  190 PYTT 193
HTH_21 pfam13276
HTH-like domain; This domain contains a predicted helix-turn-helix suggesting a DNA-binding ...
 35-93 7.81e-14

HTH-like domain; This domain contains a predicted helix-turn-helix suggesting a DNA-binding function.


Pssm-ID: 463824 [Multi-domain]  Cd Length: 60  Bit Score: 60.28  E-value: 7.81e-14
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2710808042  35 SANKELLEAIQKIYQVSKCRYGAPKIHAELKALGK-SCNLKTVQSIMQKNDIRAILKRKF 93
Cdd:pfam13276   1 ELEDELLEAIREIFEESRGTYGYRRITAELRREGGiRVNRKRVARLMRELGLRARRRRKR 60
Tra5 COG2801
Transposase InsO and inactivated derivatives [Mobilome: prophages, transposons];
18-93 3.19e-12

Transposase InsO and inactivated derivatives [Mobilome: prophages, transposons];


Pssm-ID: 442053 [Multi-domain]  Cd Length: 309  Bit Score: 60.55  E-value: 3.19e-12
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2710808042  18 SASGYYKWTTRKISSRESANKELLEAIQKIYQVSKcRYGAPKIHAELKALGKSCNLKTVQSIMQKNDIRAILKRKF 93
Cdd:COG2801    51 ARSRRRRRLRRPRSYRADEDAELLERIKEIFAESP-RYGYRRITAELRREGIAVNRKRVRRLMRELGLQARRRRKK 125
PHA02517 PHA02517
putative transposase OrfB; Reviewed
 16-97 1.90e-07

putative transposase OrfB; Reviewed


Pssm-ID: 222853 [Multi-domain]  Cd Length: 277  Bit Score: 47.17  E-value: 1.90e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2710808042  16 GFSASGYYKWTTR-----KISSRESANKELLEAIQKIYQVSKCRYGAPKIHAELKALGKSCNLKTVQSIMQKNDIRAILK 90
Cdd:PHA02517    2 GIAPSTYYRCQQQrhhpdKRRARAQHDDWLKSEILRVYDENHQVYGVRKVWRQLNREGIRVARCTVGRLMKELGLAGVLR 81


                  ....*..
gi 2710808042  91 RKFIALS 97
Cdd:PHA02517   82 GKKVRTT 88
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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