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Conserved domains on  [gi|2724525414|ref|WP_342626700|]
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MULTISPECIES: transposase [unclassified Pseudoalteromonas]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
transpos_IS4_1 super family cl41338
IS4 family transposase;
2-33 2.96e-09

IS4 family transposase;


The actual alignment was detected with superfamily member NF033592:

Pssm-ID: 468101 [Multi-domain]  Cd Length: 332  Bit Score: 48.80  E-value: 2.96e-09
                          10        20        30
                  ....*....|....*....|....*....|..
gi 2724525414   2 KGQLLLADRGYYSGSYIHELDKAGGFYVLRAK 33
Cdd:NF033592  176 PGDLLLFDRGYFSYELFAEIQEAGAYFVSRLK 207
 
Name Accession Description Interval E-value
transpos_IS4_1 NF033592
IS4 family transposase;
2-33 2.96e-09

IS4 family transposase;


Pssm-ID: 468101 [Multi-domain]  Cd Length: 332  Bit Score: 48.80  E-value: 2.96e-09
                          10        20        30
                  ....*....|....*....|....*....|..
gi 2724525414   2 KGQLLLADRGYYSGSYIHELDKAGGFYVLRAK 33
Cdd:NF033592  176 PGDLLLFDRGYFSYELFAEIQEAGAYFVSRLK 207
DDE_Tnp_1 pfam01609
Transposase DDE domain; Transposase proteins are necessary for efficient DNA transposition. ...
1-34 5.83e-05

Transposase DDE domain; Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction. This family contains transposases for IS4, IS421, IS5377, IS427, IS402, IS1355, IS5, which was original isolated in bacteriophage lambda.


Pssm-ID: 376573 [Multi-domain]  Cd Length: 196  Bit Score: 36.84  E-value: 5.83e-05
                          10        20        30
                  ....*....|....*....|....*....|....
gi 2724525414   1 MKGQLLLADRGYYSGSYIHELDKAGGFYVLRAKG 34
Cdd:pfam01609  75 RKGRLVLADAGYGGKELLDKLEEKGVDYLIRLKK 108
 
Name Accession Description Interval E-value
transpos_IS4_1 NF033592
IS4 family transposase;
2-33 2.96e-09

IS4 family transposase;


Pssm-ID: 468101 [Multi-domain]  Cd Length: 332  Bit Score: 48.80  E-value: 2.96e-09
                          10        20        30
                  ....*....|....*....|....*....|..
gi 2724525414   2 KGQLLLADRGYYSGSYIHELDKAGGFYVLRAK 33
Cdd:NF033592  176 PGDLLLFDRGYFSYELFAEIQEAGAYFVSRLK 207
DDE_Tnp_1 pfam01609
Transposase DDE domain; Transposase proteins are necessary for efficient DNA transposition. ...
1-34 5.83e-05

Transposase DDE domain; Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction. This family contains transposases for IS4, IS421, IS5377, IS427, IS402, IS1355, IS5, which was original isolated in bacteriophage lambda.


Pssm-ID: 376573 [Multi-domain]  Cd Length: 196  Bit Score: 36.84  E-value: 5.83e-05
                          10        20        30
                  ....*....|....*....|....*....|....
gi 2724525414   1 MKGQLLLADRGYYSGSYIHELDKAGGFYVLRAKG 34
Cdd:pfam01609  75 RKGRLVLADAGYGGKELLDKLEEKGVDYLIRLKK 108
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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