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Conserved domains on  [gi|2730304476|ref|WP_344496300|]
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caspase, EACC1-associated type [Streptomyces enissocaesilis]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
COG4249 COG4249
Uncharacterized conserved protein, contains caspase domain [General function prediction only];
2-247 4.04e-54

Uncharacterized conserved protein, contains caspase domain [General function prediction only];


:

Pssm-ID: 443391  Cd Length: 238  Bit Score: 184.37  E-value: 4.04e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2730304476   2 NAQAFGDGHRRALLIGTGTYDHpeLPTLLSPDVDCTRLNEVLSDPeigQFE-VQQLVDADRSVLERAIGELFLTAEHRDV 80
Cdd:COG4249     1 AAAAAAAEKRVALVIGNSAYQD--LPPLPNAVNDAEALAEALREA---GFDeVILLTDATRAEIRRALRDFFAKAQPGDV 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2730304476  81 CLLYFSCHGVVNrNDKLYFAVRNTDPDRPAYSAISASLVHEVMDECLARSIVAVVDCCYSGLFIPGAKGRVSAGFEEALA 160
Cdd:COG4249    76 ALFYFAGHGIQD-DGENYLLPVDASPDDLESTAISLSELLDALAESPAKKVLVILDACRSGPFARGGRRSAGPSSSRGLA 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2730304476 161 ----GRGRVIITAGTRVQRAWEGDHSDASApalsrFTQTIVDGLRsGDADlnGDGLITVQELFRYASERLHQN-GIAQTP 235
Cdd:COG4249   155 elaaGRGTLVLTASAPGQVALEGPEGGHGV-----FTYALLEGLR-GPAD--GDGGITLEELFKYVRRRVRELtGGKQTP 226

                         250
                  ....*....|..
gi 2730304476 236 RMGGEIQYDIAL 247
Cdd:COG4249   227 WFISSLGGDFVL 238
PQQ_2 super family cl38403
PQQ-like domain; This domain contains several repeats of the PQQ repeat.
 348-574 9.36e-15

PQQ-like domain; This domain contains several repeats of the PQQ repeat.


The actual alignment was detected with superfamily member pfam13360:

Pssm-ID: 433144 [Multi-domain]  Cd Length: 233  Bit Score: 73.98  E-value: 9.36e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2730304476 348 WLRSVDLRTGRPR-RAPRLQVCDGLLGVCADILYAPGPDGCLHSIDLPSGEIRWSQSLGKQAIGcAPQATAGNVIIMAee 426
Cdd:pfam13360   4 VVTALDAATGAELwRVDLETGLGGGVAVDGGRLFVATGGGQLVALDAATGKLLWRQTLSGEVLG-APLVAGGRVFVVA-- 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2730304476 427 pqpsnetanrSGGHVVAVLEATGHPNWSYQ-PEGQL----SRDWVVADSGIYTIQrvepSQQRIVAVDPTNGEPLW---- 497
Cdd:pfam13360  81 ----------GDGSLIALDAADGRRLWSYQrSGEPLalrsSGSPAVVGDTVVAGF----SSGKLVALDPATGKVRWeapl 146

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2730304476 498 -RFDVAADLAAAPAVTSELVIYGDV------DNRLVALDAKSGAQLWEGKTKGRvlTRPFAVGDTLFTADRAATVTAWKL 570
Cdd:pfam13360 147 aAPRGTNELERLVDITGTPVVAGGRvfasayQGRLVAFDAATGRRLWTREISGP--NGPILDGDLLYVVSDDGELYALDR 224


                  ....
gi 2730304476 571 SVGR 574
Cdd:pfam13360 225 ATGA 228
 
Name Accession Description Interval E-value
COG4249 COG4249
Uncharacterized conserved protein, contains caspase domain [General function prediction only];
2-247 4.04e-54

Uncharacterized conserved protein, contains caspase domain [General function prediction only];


Pssm-ID: 443391  Cd Length: 238  Bit Score: 184.37  E-value: 4.04e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2730304476   2 NAQAFGDGHRRALLIGTGTYDHpeLPTLLSPDVDCTRLNEVLSDPeigQFE-VQQLVDADRSVLERAIGELFLTAEHRDV 80
Cdd:COG4249     1 AAAAAAAEKRVALVIGNSAYQD--LPPLPNAVNDAEALAEALREA---GFDeVILLTDATRAEIRRALRDFFAKAQPGDV 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2730304476  81 CLLYFSCHGVVNrNDKLYFAVRNTDPDRPAYSAISASLVHEVMDECLARSIVAVVDCCYSGLFIPGAKGRVSAGFEEALA 160
Cdd:COG4249    76 ALFYFAGHGIQD-DGENYLLPVDASPDDLESTAISLSELLDALAESPAKKVLVILDACRSGPFARGGRRSAGPSSSRGLA 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2730304476 161 ----GRGRVIITAGTRVQRAWEGDHSDASApalsrFTQTIVDGLRsGDADlnGDGLITVQELFRYASERLHQN-GIAQTP 235
Cdd:COG4249   155 elaaGRGTLVLTASAPGQVALEGPEGGHGV-----FTYALLEGLR-GPAD--GDGGITLEELFKYVRRRVRELtGGKQTP 226

                         250
                  ....*....|..
gi 2730304476 236 RMGGEIQYDIAL 247
Cdd:COG4249   227 WFISSLGGDFVL 238
PQQ_2 pfam13360
PQQ-like domain; This domain contains several repeats of the PQQ repeat.
 348-574 9.36e-15

PQQ-like domain; This domain contains several repeats of the PQQ repeat.


Pssm-ID: 433144 [Multi-domain]  Cd Length: 233  Bit Score: 73.98  E-value: 9.36e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2730304476 348 WLRSVDLRTGRPR-RAPRLQVCDGLLGVCADILYAPGPDGCLHSIDLPSGEIRWSQSLGKQAIGcAPQATAGNVIIMAee 426
Cdd:pfam13360   4 VVTALDAATGAELwRVDLETGLGGGVAVDGGRLFVATGGGQLVALDAATGKLLWRQTLSGEVLG-APLVAGGRVFVVA-- 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2730304476 427 pqpsnetanrSGGHVVAVLEATGHPNWSYQ-PEGQL----SRDWVVADSGIYTIQrvepSQQRIVAVDPTNGEPLW---- 497
Cdd:pfam13360  81 ----------GDGSLIALDAADGRRLWSYQrSGEPLalrsSGSPAVVGDTVVAGF----SSGKLVALDPATGKVRWeapl 146

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2730304476 498 -RFDVAADLAAAPAVTSELVIYGDV------DNRLVALDAKSGAQLWEGKTKGRvlTRPFAVGDTLFTADRAATVTAWKL 570
Cdd:pfam13360 147 aAPRGTNELERLVDITGTPVVAGGRvfasayQGRLVAFDAATGRRLWTREISGP--NGPILDGDLLYVVSDDGELYALDR 224


                  ....
gi 2730304476 571 SVGR 574
Cdd:pfam13360 225 ATGA 228
Peptidase_C14 pfam00656
Caspase domain;
10-235 6.27e-14

Caspase domain;


Pssm-ID: 425803  Cd Length: 213  Bit Score: 71.20  E-value: 6.27e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2730304476  10 HRRALLIGTGTYDHPELPtLLSPDVDCTRLNEVLSdpEIGqFEVQQLVDADRSVLERAIGELFLTAEHRD-----VCLLY 84
Cdd:pfam00656   1 RGLALIIGNNNYPGTKAP-LRGCDNDAEALAKTLK--SLG-FEVRVFEDLTAEEIRRALRDFAARADHSDgdsfvVVLLY 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2730304476  85 FSCHGVVNRNDKLYFavrnTDPDRPAYSAISASLvheVMDECLARSI----VAVVDCCYSGLFipgAKGRVSAGFeeala 160
Cdd:pfam00656  77 YSGHGEQVPGGDIYG----TDEYLVPVDALTNLF---TGDDCLPSLVgkpkLFIIDACRGNLE---DGGVVEADF----- 141

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2730304476 161 grgrVIITAGTRVQRAWEGDHSDasapalSRFTQTIVDGLRSGDADLngdgliTVQELFRYASERLHQNGI-AQTP 235
Cdd:pfam00656 142 ----LVAYSTAPGQVSWRNTGSG------SWFIQALCQVLREYGHGL------DLLSLLTKVRRRVAEATGkKQMP 201
PQQ COG1520
Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat [Cell ...
 385-610 8.18e-11

Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 441129 [Multi-domain]  Cd Length: 370  Bit Score: 64.06  E-value: 8.18e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2730304476 385 DGCLHSIDLPSGEIRWSQSLGKQAI---GCAPQATAGNVIIMAeepqpsnetanRSGGHVVAVLEATGHPNWSY---QPE 458
Cdd:COG1520   146 DGRVYALDAATGERLWSYQRPVPALtlrGTSSPVIVGGAVLVG-----------FANGKLVALDLANGQPLWEQrvaQPR 214

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2730304476 459 G--QLSR------DWVVADSGIYTIqrvepS-QQRIVAVDPTNGEPLWRfdvAADLAAAPAVTSELVIYG-DVDNRLVAL 528
Cdd:COG1520   215 GrtELERlvdvdgTPVVDGGVVYAV-----AyQGRLAALDLRSGRVLWS---RDLSSYTGLAVDGNNLYVtDDDGRVWAL 286

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2730304476 529 DAKSGAQLWEGKT-KGRVLTRPFAVGDTLFTADRAATVTaWkLS------VGRklrscevlLSPDQQG---SPAVTNDWM 598
Cdd:COG1520   287 DRRNGAELWKQDAlLYRGLTAPVVLGDYVVVGDFEGYLH-W-LSrddgslVAR--------LRVDGSGiraAPVVVGDTL 356

                         250
                  ....*....|..
gi 2730304476 599 YITDSHGDIRAL 610
Cdd:COG1520   357 YVQTRDGTLAAL 368
assembly_YfgL TIGR03300
outer membrane assembly lipoprotein YfgL; Members of this protein family are YfgL, a ...
 385-560 9.42e-11

outer membrane assembly lipoprotein YfgL; Members of this protein family are YfgL, a lipoprotein component of a complex that acts protein insertion into the bacterial outer membrane. Other members of this complex are NlpB, YfiO, and YaeT. This protein contains multiple copies of a repeat that, in other contexts, are associated with binding of the coenzyme PQQ. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 274511 [Multi-domain]  Cd Length: 377  Bit Score: 63.80  E-value: 9.42e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2730304476 385 DGCLHSIDLPSGEIRWSQSLGKQAI---GCAPQATAGNVIIMAEepqpsnetanrSGGHVVAVLEATGHPNWS---YQPE 458
Cdd:TIGR03300 154 DGRLTALDAATGERLWTYSRVTPPLtlrGSASPVIADGGVLVGF-----------AGGKLVALDLQTGQPLWEqrvALPK 222

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2730304476 459 G--QLSR------DWVVADSGIYTIQrvepSQQRIVAVDPTNGEPLWRfdvAADLAAAPAVTSELVIYG-DVDNRLVALD 529
Cdd:TIGR03300 223 GrtELERlvdvdgDPVVDGGQVYAVS----YQGRVAALDLRSGRVLWK---RDASSYQGPAVDDNRLYVtDADGVVVALD 295

                         170       180       190
                  ....*....|....*....|....*....|..
gi 2730304476 530 AKSGAQLWE-GKTKGRVLTRPFAVGDTLFTAD 560
Cdd:TIGR03300 296 RRSGSELWKnDELKYRQLTAPAVLGGYLVVGD 327
BamB_YfgL cd10276
Beta-barrel assembly machinery (Bam) complex component B and related proteins; BamB (YflG) is ...
 374-538 1.86e-07

Beta-barrel assembly machinery (Bam) complex component B and related proteins; BamB (YflG) is a non-essential component of the beta-barrel assembly machinery (Bam), a multi-subunit complex that inserts proteins with beta-barrel topology into the outer membrane. BamB has been found to interact with BamA, which in turn binds and stabilizes pre-folded beta-barrel proteins; it has been suggested that BamB participates in the stabilization.


Pssm-ID: 199834 [Multi-domain]  Cd Length: 358  Bit Score: 53.49  E-value: 1.86e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2730304476 374 VCADILYAPGPDGCLHSIDLPSGEIRWSQSLGKQAIGCAPQATAGNVIIMAeepqpsnetanRSGGHVVAVLEATGHPNW 453
Cdd:cd10276    36 VAGDMVYAADANGQVSAFNATTGKIIWETSLSGKGFLGGTPAVGNGKIFVG-----------TESGYLYALDAKDGSELW 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2730304476 454 SYQ-PEGQLSRDWVVADSGIYtiqrVEPSQQRIVAVDPTNGEPLWRFDVAADLAAAPAVTSELVIYGDV-----DNRLVA 527
Cdd:cd10276   105 RTEvSDSQLLSPPTYADGKIY----VGTGDGRLYYCNAETGKVVWNRTSTAPELSLRGGAAPVGAYDVVfvgdgNGTVVA 180

                         170
                  ....*....|.
gi 2730304476 528 LDAKSGAQLWE 538
Cdd:cd10276   181 LNTGTGVDIWE 191
PRK11138 PRK11138
outer membrane biogenesis protein BamB; Provisional
 386-560 1.03e-03

outer membrane biogenesis protein BamB; Provisional


Pssm-ID: 236857 [Multi-domain]  Cd Length: 394  Bit Score: 41.84  E-value: 1.03e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2730304476 386 GCLHSIDLPSGEIRWS-----QSLGKQAIGcAPQATAGNVIImaeepqpsnETANrsgGHVVAVLEATGHPNWS---YQP 457
Cdd:PRK11138  170 GMLQALNESDGAVKWTvnldvPSLTLRGES-APATAFGGAIV---------GGDN---GRVSAVLMEQGQLIWQqriSQP 236

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2730304476 458 EG--QLSR----DW--VVADSGIYTIQrvepSQQRIVAVDPTNGEPLWRfdvaadlaAAPAVTSELVIYG------DVDN 523
Cdd:PRK11138  237 TGatEIDRlvdvDTtpVVVGGVVYALA----YNGNLVALDLRSGQIVWK--------REYGSVNDFAVDGgriylvDQND 304

                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 2730304476 524 RLVALDAKSGAQLWE-GKTKGRVLTRPFAVGDTLFTAD 560
Cdd:PRK11138  305 RVYALDTRGGVELWSqSDLLHRLLTAPVLYNGYLVVGD 342
 
Name Accession Description Interval E-value
COG4249 COG4249
Uncharacterized conserved protein, contains caspase domain [General function prediction only];
2-247 4.04e-54

Uncharacterized conserved protein, contains caspase domain [General function prediction only];


Pssm-ID: 443391  Cd Length: 238  Bit Score: 184.37  E-value: 4.04e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2730304476   2 NAQAFGDGHRRALLIGTGTYDHpeLPTLLSPDVDCTRLNEVLSDPeigQFE-VQQLVDADRSVLERAIGELFLTAEHRDV 80
Cdd:COG4249     1 AAAAAAAEKRVALVIGNSAYQD--LPPLPNAVNDAEALAEALREA---GFDeVILLTDATRAEIRRALRDFFAKAQPGDV 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2730304476  81 CLLYFSCHGVVNrNDKLYFAVRNTDPDRPAYSAISASLVHEVMDECLARSIVAVVDCCYSGLFIPGAKGRVSAGFEEALA 160
Cdd:COG4249    76 ALFYFAGHGIQD-DGENYLLPVDASPDDLESTAISLSELLDALAESPAKKVLVILDACRSGPFARGGRRSAGPSSSRGLA 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2730304476 161 ----GRGRVIITAGTRVQRAWEGDHSDASApalsrFTQTIVDGLRsGDADlnGDGLITVQELFRYASERLHQN-GIAQTP 235
Cdd:COG4249   155 elaaGRGTLVLTASAPGQVALEGPEGGHGV-----FTYALLEGLR-GPAD--GDGGITLEELFKYVRRRVRELtGGKQTP 226

                         250
                  ....*....|..
gi 2730304476 236 RMGGEIQYDIAL 247
Cdd:COG4249   227 WFISSLGGDFVL 238
PQQ_2 pfam13360
PQQ-like domain; This domain contains several repeats of the PQQ repeat.
 348-574 9.36e-15

PQQ-like domain; This domain contains several repeats of the PQQ repeat.


Pssm-ID: 433144 [Multi-domain]  Cd Length: 233  Bit Score: 73.98  E-value: 9.36e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2730304476 348 WLRSVDLRTGRPR-RAPRLQVCDGLLGVCADILYAPGPDGCLHSIDLPSGEIRWSQSLGKQAIGcAPQATAGNVIIMAee 426
Cdd:pfam13360   4 VVTALDAATGAELwRVDLETGLGGGVAVDGGRLFVATGGGQLVALDAATGKLLWRQTLSGEVLG-APLVAGGRVFVVA-- 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2730304476 427 pqpsnetanrSGGHVVAVLEATGHPNWSYQ-PEGQL----SRDWVVADSGIYTIQrvepSQQRIVAVDPTNGEPLW---- 497
Cdd:pfam13360  81 ----------GDGSLIALDAADGRRLWSYQrSGEPLalrsSGSPAVVGDTVVAGF----SSGKLVALDPATGKVRWeapl 146

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2730304476 498 -RFDVAADLAAAPAVTSELVIYGDV------DNRLVALDAKSGAQLWEGKTKGRvlTRPFAVGDTLFTADRAATVTAWKL 570
Cdd:pfam13360 147 aAPRGTNELERLVDITGTPVVAGGRvfasayQGRLVAFDAATGRRLWTREISGP--NGPILDGDLLYVVSDDGELYALDR 224


                  ....
gi 2730304476 571 SVGR 574
Cdd:pfam13360 225 ATGA 228
Peptidase_C14 pfam00656
Caspase domain;
10-235 6.27e-14

Caspase domain;


Pssm-ID: 425803  Cd Length: 213  Bit Score: 71.20  E-value: 6.27e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2730304476  10 HRRALLIGTGTYDHPELPtLLSPDVDCTRLNEVLSdpEIGqFEVQQLVDADRSVLERAIGELFLTAEHRD-----VCLLY 84
Cdd:pfam00656   1 RGLALIIGNNNYPGTKAP-LRGCDNDAEALAKTLK--SLG-FEVRVFEDLTAEEIRRALRDFAARADHSDgdsfvVVLLY 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2730304476  85 FSCHGVVNRNDKLYFavrnTDPDRPAYSAISASLvheVMDECLARSI----VAVVDCCYSGLFipgAKGRVSAGFeeala 160
Cdd:pfam00656  77 YSGHGEQVPGGDIYG----TDEYLVPVDALTNLF---TGDDCLPSLVgkpkLFIIDACRGNLE---DGGVVEADF----- 141

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2730304476 161 grgrVIITAGTRVQRAWEGDHSDasapalSRFTQTIVDGLRSGDADLngdgliTVQELFRYASERLHQNGI-AQTP 235
Cdd:pfam00656 142 ----LVAYSTAPGQVSWRNTGSG------SWFIQALCQVLREYGHGL------DLLSLLTKVRRRVAEATGkKQMP 201
PQQ_2 pfam13360
PQQ-like domain; This domain contains several repeats of the PQQ repeat.
 384-610 1.78e-13

PQQ-like domain; This domain contains several repeats of the PQQ repeat.


Pssm-ID: 433144 [Multi-domain]  Cd Length: 233  Bit Score: 70.12  E-value: 1.78e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2730304476 384 PDGCLHSIDLPSGEIRWSQSLGkQAIGCAPQATAGNVIIMAEEPQpsnetanrsgghVVAVLEATGHPNWSYQPEGQLSR 463
Cdd:pfam13360   1 ADGVVTALDAATGAELWRVDLE-TGLGGGVAVDGGRLFVATGGGQ------------LVALDAATGKLLWRQTLSGEVLG 67

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2730304476 464 DWVVADSGIYtiqrVEPSQQRIVAVDPTNGEPLWRFDVAADLAAAPAVTS-----ELVIYGDVDNRLVALDAKSGAQLWE 538
Cdd:pfam13360  68 APLVAGGRVF----VVAGDGSLIALDAADGRRLWSYQRSGEPLALRSSGSpavvgDTVVAGFSSGKLVALDPATGKVRWE 143

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2730304476 539 GKTK-----------GRVLTRPFAVGDTLFTADRAATVTAWKLSVGRKLRSCEVLLSpdqqGSPAVTNDWMYITDSHGDI 607
Cdd:pfam13360 144 APLAaprgtnelerlVDITGTPVVAGGRVFASAYQGRLVAFDAATGRRLWTREISGP----NGPILDGDLLYVVSDDGEL 219


                  ...
gi 2730304476 608 RAL 610
Cdd:pfam13360 220 YAL 222
PQQ COG1520
Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat [Cell ...
 385-610 8.18e-11

Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 441129 [Multi-domain]  Cd Length: 370  Bit Score: 64.06  E-value: 8.18e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2730304476 385 DGCLHSIDLPSGEIRWSQSLGKQAI---GCAPQATAGNVIIMAeepqpsnetanRSGGHVVAVLEATGHPNWSY---QPE 458
Cdd:COG1520   146 DGRVYALDAATGERLWSYQRPVPALtlrGTSSPVIVGGAVLVG-----------FANGKLVALDLANGQPLWEQrvaQPR 214

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2730304476 459 G--QLSR------DWVVADSGIYTIqrvepS-QQRIVAVDPTNGEPLWRfdvAADLAAAPAVTSELVIYG-DVDNRLVAL 528
Cdd:COG1520   215 GrtELERlvdvdgTPVVDGGVVYAV-----AyQGRLAALDLRSGRVLWS---RDLSSYTGLAVDGNNLYVtDDDGRVWAL 286

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2730304476 529 DAKSGAQLWEGKT-KGRVLTRPFAVGDTLFTADRAATVTaWkLS------VGRklrscevlLSPDQQG---SPAVTNDWM 598
Cdd:COG1520   287 DRRNGAELWKQDAlLYRGLTAPVVLGDYVVVGDFEGYLH-W-LSrddgslVAR--------LRVDGSGiraAPVVVGDTL 356

                         250
                  ....*....|..
gi 2730304476 599 YITDSHGDIRAL 610
Cdd:COG1520   357 YVQTRDGTLAAL 368
assembly_YfgL TIGR03300
outer membrane assembly lipoprotein YfgL; Members of this protein family are YfgL, a ...
 385-560 9.42e-11

outer membrane assembly lipoprotein YfgL; Members of this protein family are YfgL, a lipoprotein component of a complex that acts protein insertion into the bacterial outer membrane. Other members of this complex are NlpB, YfiO, and YaeT. This protein contains multiple copies of a repeat that, in other contexts, are associated with binding of the coenzyme PQQ. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 274511 [Multi-domain]  Cd Length: 377  Bit Score: 63.80  E-value: 9.42e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2730304476 385 DGCLHSIDLPSGEIRWSQSLGKQAI---GCAPQATAGNVIIMAEepqpsnetanrSGGHVVAVLEATGHPNWS---YQPE 458
Cdd:TIGR03300 154 DGRLTALDAATGERLWTYSRVTPPLtlrGSASPVIADGGVLVGF-----------AGGKLVALDLQTGQPLWEqrvALPK 222

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2730304476 459 G--QLSR------DWVVADSGIYTIQrvepSQQRIVAVDPTNGEPLWRfdvAADLAAAPAVTSELVIYG-DVDNRLVALD 529
Cdd:TIGR03300 223 GrtELERlvdvdgDPVVDGGQVYAVS----YQGRVAALDLRSGRVLWK---RDASSYQGPAVDDNRLYVtDADGVVVALD 295

                         170       180       190
                  ....*....|....*....|....*....|..
gi 2730304476 530 AKSGAQLWE-GKTKGRVLTRPFAVGDTLFTAD 560
Cdd:TIGR03300 296 RRSGSELWKnDELKYRQLTAPAVLGGYLVVGD 327
PQQ COG1520
Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat [Cell ...
 376-610 1.08e-10

Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 441129 [Multi-domain]  Cd Length: 370  Bit Score: 63.68  E-value: 1.08e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2730304476 376 ADILYAPGPDGCLHSIDLPSGEIRWSQSLGKQAIGcaPQATAGNVIIMAeepqpsneTANrsgGHVVAVLEATGHPNWSY 455
Cdd:COG1520    57 GDRVYAADADGRVAALDAATGKELWRVDLGEPLSG--GVGADGGLVVVG--------TED---GEVIALDADDGEELWRA 123

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2730304476 456 QPEGQ-LSRdwVVADSGI---YTIQRvepsqqRIVAVDPTNGEPLWRFDVAADL-----AAAPAVTSELVIYGDVDNRLV 526
Cdd:COG1520   124 RLSSEvLAA--PAVAGGRvvvRTGDG------RVYALDAATGERLWSYQRPVPAltlrgTSSPVIVGGAVLVGFANGKLV 195

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2730304476 527 ALDAKSGAQLWE---GKTKGR--------VLTRPFAVGDTLFTADRAATVTAWKLSVGRklrsceVLLSPDQQGS--PAV 593
Cdd:COG1520   196 ALDLANGQPLWEqrvAQPRGRtelerlvdVDGTPVVDGGVVYAVAYQGRLAALDLRSGR------VLWSRDLSSYtgLAV 269

                         250
                  ....*....|....*..
gi 2730304476 594 TNDWMYITDSHGDIRAL 610
Cdd:COG1520   270 DGNNLYVTDDDGRVWAL 286
assembly_YfgL TIGR03300
outer membrane assembly lipoprotein YfgL; Members of this protein family are YfgL, a ...
 377-610 2.51e-10

outer membrane assembly lipoprotein YfgL; Members of this protein family are YfgL, a lipoprotein component of a complex that acts protein insertion into the bacterial outer membrane. Other members of this complex are NlpB, YfiO, and YaeT. This protein contains multiple copies of a repeat that, in other contexts, are associated with binding of the coenzyme PQQ. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 274511 [Multi-domain]  Cd Length: 377  Bit Score: 62.64  E-value: 2.51e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2730304476 377 DILYAPGPDGCLHSIDLPSGEIRWSQSLGKQaIGCAPQATAGNVIIMAEEpqpsnetanrsgGHVVAVLEATGHPNWSYQ 456
Cdd:TIGR03300  66 GKVYAADADGTVAALDAETGKRLWRVDLDER-LSGGVGADGGLVFVGTEK------------GEVIALDAEDGKELWRAK 132

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2730304476 457 PEGQ-LSRdwVVADSGIYTIQrvePSQQRIVAVDPTNGEPLWRFDVAADL-----AAAPAVTSELVIYGDVDNRLVALDA 530
Cdd:TIGR03300 133 LSSEvLSP--PLVANGLVVVR---TNDGRLTALDAATGERLWTYSRVTPPltlrgSASPVIADGGVLVGFAGGKLVALDL 207

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2730304476 531 KSGAQLWEGKT---KGR--------VLTRPFAVGDTLFTADRAATVTAWKLSVGRKLRSCEVllSPDQQgsPAVTNDWMY 599
Cdd:TIGR03300 208 QTGQPLWEQRValpKGRtelerlvdVDGDPVVDGGQVYAVSYQGRVAALDLRSGRVLWKRDA--SSYQG--PAVDDNRLY 283

                         250
                  ....*....|.
gi 2730304476 600 ITDSHGDIRAL 610
Cdd:TIGR03300 284 VTDADGVVVAL 294
Gcd COG4993
Glucose dehydrogenase, PQQ-dependent [Carbohydrate transport and metabolism];
483-558 1.06e-07

Glucose dehydrogenase, PQQ-dependent [Carbohydrate transport and metabolism];


Pssm-ID: 444017 [Multi-domain]  Cd Length: 515  Bit Score: 54.78  E-value: 1.06e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2730304476 483 QRIVAVDPTNGEPLWRFDVAADLAAAPAVTS--------ELVIYGDVDNRLVALDAKSGAQLWEGKT----KGRVLTR-P 549
Cdd:COG4993    65 NRVFALDAATGKELWRYDPKLPDDAACCDVVnrgvayydGRIFLGTLDGRLVALDAKTGKVCWDVKVgdpkKGYTITSaP 144


                  ....*....
gi 2730304476 550 FAVGDTLFT 558
Cdd:COG4993   145 LVVKDKVIV 153
BamB_YfgL cd10276
Beta-barrel assembly machinery (Bam) complex component B and related proteins; BamB (YflG) is ...
 374-538 1.86e-07

Beta-barrel assembly machinery (Bam) complex component B and related proteins; BamB (YflG) is a non-essential component of the beta-barrel assembly machinery (Bam), a multi-subunit complex that inserts proteins with beta-barrel topology into the outer membrane. BamB has been found to interact with BamA, which in turn binds and stabilizes pre-folded beta-barrel proteins; it has been suggested that BamB participates in the stabilization.


Pssm-ID: 199834 [Multi-domain]  Cd Length: 358  Bit Score: 53.49  E-value: 1.86e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2730304476 374 VCADILYAPGPDGCLHSIDLPSGEIRWSQSLGKQAIGCAPQATAGNVIIMAeepqpsnetanRSGGHVVAVLEATGHPNW 453
Cdd:cd10276    36 VAGDMVYAADANGQVSAFNATTGKIIWETSLSGKGFLGGTPAVGNGKIFVG-----------TESGYLYALDAKDGSELW 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2730304476 454 SYQ-PEGQLSRDWVVADSGIYtiqrVEPSQQRIVAVDPTNGEPLWRFDVAADLAAAPAVTSELVIYGDV-----DNRLVA 527
Cdd:cd10276   105 RTEvSDSQLLSPPTYADGKIY----VGTGDGRLYYCNAETGKVVWNRTSTAPELSLRGGAAPVGAYDVVfvgdgNGTVVA 180

                         170
                  ....*....|.
gi 2730304476 528 LDAKSGAQLWE 538
Cdd:cd10276   181 LNTGTGVDIWE 191
BamB_YfgL cd10276
Beta-barrel assembly machinery (Bam) complex component B and related proteins; BamB (YflG) is ...
 331-610 2.36e-07

Beta-barrel assembly machinery (Bam) complex component B and related proteins; BamB (YflG) is a non-essential component of the beta-barrel assembly machinery (Bam), a multi-subunit complex that inserts proteins with beta-barrel topology into the outer membrane. BamB has been found to interact with BamA, which in turn binds and stabilizes pre-folded beta-barrel proteins; it has been suggested that BamB participates in the stabilization.


Pssm-ID: 199834 [Multi-domain]  Cd Length: 358  Bit Score: 53.10  E-value: 2.36e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2730304476 331 GSPAFHGGAAHFPGPGRWLRSVDLRTGR---PRRAPRLQVCDGLLGVCADILYAPGPDGCLHSIDLPSGEIRWSQSLGKQ 407
Cdd:cd10276    32 LTPVVAGDMVYAADANGQVSAFNATTGKiiwETSLSGKGFLGGTPAVGNGKIFVGTESGYLYALDAKDGSELWRTEVSDS 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2730304476 408 AIGCAP-------------------QATAGNVIIMAEEPQPS--------------NETANRSGGHVVAVLEATGHPNWS 454
Cdd:cd10276   112 QLLSPPtyadgkiyvgtgdgrlyycNAETGKVVWNRTSTAPElslrggaapvgaydVVFVGDGNGTVVALNTGTGVDIWE 191

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2730304476 455 YQ---PEGQLSRDWVV------ADSGIYTIqrVEPSQQRIVAVDPTNGEPLWRfdvaadlAAAPAVTSELVIY------G 519
Cdd:cd10276   192 FSvsePRGRTELPRMIdssvtyVVVGGYLY--STSYQGYLVALDFESGQFLWS-------RKASGGTSTSTDAngrvyvG 262

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2730304476 520 DVDNRLVALDAKSGAQLWE-GKTKGRVLTRP-FAVGDTLFTADRAATVTAWkLSVGRKLRSCEVLLSPDQ--QGSPAVTN 595
Cdd:cd10276   263 DGEGSLYCLDASTGDELWSqTVLLGRVLSSPaIYVGVYIYVTDNAEGYLYC-LKDNDGLTVARVEVDYSQyiLQGPAVSD 341

                         330
                  ....*....|....*
gi 2730304476 596 DWMYITDSHGDIRAL 610
Cdd:cd10276   342 GWLYYGTDDGYLYAL 356
PQQ_DH_like cd00216
PQQ-dependent dehydrogenases and related proteins; This family is composed of dehydrogenases ...
 382-576 5.60e-07

PQQ-dependent dehydrogenases and related proteins; This family is composed of dehydrogenases with pyrroloquinoline quinone (PQQ) as a cofactor, such as ethanol, methanol, and membrane-bound glucose dehydrogenases. The alignment model contains an 8-bladed beta-propeller, and the family also includes distantly related proteins which are not enzymatically active and do not bind PQQ.


Pssm-ID: 199833 [Multi-domain]  Cd Length: 434  Bit Score: 52.22  E-value: 5.60e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2730304476 382 PGPDGCLHSIDLPSGEIRWSQSLGKQAIGCAPQATAGNVIIM-AEEPQPSNETANRSGGH------VVAVLEATGHPNWS 454
Cdd:cd00216   169 PGKDSTVTDRNTPTGDEHTWTSGGGTGWSSAAYDAELNLIYVgGGNPTPWNWGGNRTPGDnlytssIVAVNADTGEMKWQ 248

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2730304476 455 YQPEGQLSRDWVVADSGIYTIQRVEPSQQRIV----------AVDPTNGEPLWRFDVAADLAAAPAVtselVIYGDVDNR 524
Cdd:cd00216   249 YQTTPHDAWDYDGDNTPVLADIKVKGKKVKVLfapakngnfyVLDRRNGELVSARPLVPDSYDPDRE----LFYVPANGR 324

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2730304476 525 LVALDAKSGAQLWEGKTKGRVLTRPFAV-GDTLFTADRAATVTAWKLSVGRKL 576
Cdd:cd00216   325 IMALDPVTGVVVWEKSELHPLLGGPLSTaGNLVFVGTSDGYLKAYNADTGEKL 377
PQQ COG1520
Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat [Cell ...
 466-576 1.73e-06

Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 441129 [Multi-domain]  Cd Length: 370  Bit Score: 50.58  E-value: 1.73e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2730304476 466 VVADSGIYTIQRvepsQQRIVAVDPTNGEPLWRFDVAADLAAAPAVTSELVIYGDVDNRLVALDAKSGAQLWEGKTKGRV 545
Cdd:COG1520    54 AVAGDRVYAADA----DGRVAALDAATGKELWRVDLGEPLSGGVGADGGLVVVGTEDGEVIALDADDGEELWRARLSSEV 129

                          90       100       110
                  ....*....|....*....|....*....|...
gi 2730304476 546 LTRPFAVGDTLF--TADRaaTVTAWKLSVGRKL 576
Cdd:COG1520   130 LAAPAVAGGRVVvrTGDG--RVYALDAATGERL 160
PQQ_2 pfam13360
PQQ-like domain; This domain contains several repeats of the PQQ repeat.
 284-498 1.89e-06

PQQ-like domain; This domain contains several repeats of the PQQ repeat.


Pssm-ID: 433144 [Multi-domain]  Cd Length: 233  Bit Score: 49.32  E-value: 1.89e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2730304476 284 WRVSAASGPARQPVLSDDTLIVHEKYS-LHVLDPESRR---RYPLIQTNYGgSPAFHGGAAHFPGPGRWLRSVDLRTGRP 359
Cdd:pfam13360  17 WRVDLETGLGGGVAVDGGRLFVATGGGqLVALDAATGKllwRQTLSGEVLG-APLVAGGRVFVVAGDGSLIALDAADGRR 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2730304476 360 -----RRAPRLQVC-DGLLGVCADILYAPGPDGCLHSIDLPSGEIRWSQSLGKQ----AIGCAPQATAGNVIImaeepqp 429
Cdd:pfam13360  96 lwsyqRSGEPLALRsSGSPAVVGDTVVAGFSSGKLVALDPATGKVRWEAPLAAPrgtnELERLVDITGTPVVA------- 168

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2730304476 430 SNETANRSG-GHVVAVLEATGHPNWSyQPEGQLSRDWVVADSgIYtiqrVEPSQQRIVAVDPTNGEPLWR 498
Cdd:pfam13360 169 GGRVFASAYqGRLVAFDAATGRRLWT-REISGPNGPILDGDL-LY----VVSDDGELYALDRATGAVVWK 232
assembly_YfgL TIGR03300
outer membrane assembly lipoprotein YfgL; Members of this protein family are YfgL, a ...
 466-576 1.14e-05

outer membrane assembly lipoprotein YfgL; Members of this protein family are YfgL, a lipoprotein component of a complex that acts protein insertion into the bacterial outer membrane. Other members of this complex are NlpB, YfiO, and YaeT. This protein contains multiple copies of a repeat that, in other contexts, are associated with binding of the coenzyme PQQ. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 274511 [Multi-domain]  Cd Length: 377  Bit Score: 48.00  E-value: 1.14e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2730304476 466 VVADSGIYTIQRvepsQQRIVAVDPTNGEPLWRFDVAADLAAAPAVTSELVIYGDVDNRLVALDAKSGAQLWEGKTKGRV 545
Cdd:TIGR03300  62 AVAGGKVYAADA----DGTVAALDAETGKRLWRVDLDERLSGGVGADGGLVFVGTEKGEVIALDAEDGKELWRAKLSSEV 137

                          90       100       110
                  ....*....|....*....|....*....|...
gi 2730304476 546 LTRPFAVGDTLF--TADraATVTAWKLSVGRKL 576
Cdd:TIGR03300 138 LSPPLVANGLVVvrTND--GRLTALDAATGERL 168
assembly_YfgL TIGR03300
outer membrane assembly lipoprotein YfgL; Members of this protein family are YfgL, a ...
 395-610 2.24e-05

outer membrane assembly lipoprotein YfgL; Members of this protein family are YfgL, a lipoprotein component of a complex that acts protein insertion into the bacterial outer membrane. Other members of this complex are NlpB, YfiO, and YaeT. This protein contains multiple copies of a repeat that, in other contexts, are associated with binding of the coenzyme PQQ. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 274511 [Multi-domain]  Cd Length: 377  Bit Score: 46.85  E-value: 2.24e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2730304476 395 SGEIRWSQSLGKqAIGCAPQ----ATAGNVIIMAEEpqpsnetanrsGGHVVAVLEATGHPNWSYQPEGQLSRDwVVADS 470
Cdd:TIGR03300  39 KVDQVWSASVGD-GVGHYYLrlqpAVAGGKVYAADA-----------DGTVAALDAETGKRLWRVDLDERLSGG-VGADG 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2730304476 471 GIYTI--QRVEpsqqrIVAVDPTNGEPLWRfdvaadlaaaPAVTSEL----VIYGDV------DNRLVALDAKSGAQLWE 538
Cdd:TIGR03300 106 GLVFVgtEKGE-----VIALDAEDGKELWR----------AKLSSEVlsppLVANGLvvvrtnDGRLTALDAATGERLWT 170

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2730304476 539 GKTKGRVLT-----RPFAVGDTLFTADRAATVTA---------WKLSVGRKLRSCEVLLSPDQQGSPAVTNDWMYITDSH 604
Cdd:TIGR03300 171 YSRVTPPLTlrgsaSPVIADGGVLVGFAGGKLVAldlqtgqplWEQRVALPKGRTELERLVDVDGDPVVDGGQVYAVSYQ 250


                  ....*.
gi 2730304476 605 GDIRAL 610
Cdd:TIGR03300 251 GRVAAL 256
PQQ_ADH_I cd10277
Ethanol dehydrogenase, a bacterial quinoprotein (PQQ-dependent type I alcohol dehydrogenase); ...
 485-559 1.06e-04

Ethanol dehydrogenase, a bacterial quinoprotein (PQQ-dependent type I alcohol dehydrogenase); This bacterial family of homodimeric ethanol dehydrogenases utilize pyrroloquinoline quinone (PQQ) as a cofactor. It represents proteins whose expression may be induced by ethanol, and which are similar to quinoprotein methanol dehydrogenases, but have higher specificities for ethanol and other primary and secondary alcohols. Dehydrogenases with PQQ cofactors, such as ethanol, methanol, and membrane-bound glucose dehydrogenases, form an 8-bladed beta-propeller.


Pssm-ID: 199835 [Multi-domain]  Cd Length: 529  Bit Score: 45.37  E-value: 1.06e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2730304476 485 IVAVDPTNGEPLWRFDVAADLAAAPAVT-SELVIYGDVDNRLVALDAKSGAQLWEGKTKGRVLTRP--FAVGDTLFTA 559
Cdd:cd10277   418 LQAIDPTTGKKVWEHKTPLPLWGGVLTTaGGLVFTGTPDGYFRAFDAKTGKELWEFQTGSGIIGPPvtWEVDGKQYVA 495
PQQ_ADH_I cd10277
Ethanol dehydrogenase, a bacterial quinoprotein (PQQ-dependent type I alcohol dehydrogenase); ...
 451-540 1.76e-04

Ethanol dehydrogenase, a bacterial quinoprotein (PQQ-dependent type I alcohol dehydrogenase); This bacterial family of homodimeric ethanol dehydrogenases utilize pyrroloquinoline quinone (PQQ) as a cofactor. It represents proteins whose expression may be induced by ethanol, and which are similar to quinoprotein methanol dehydrogenases, but have higher specificities for ethanol and other primary and secondary alcohols. Dehydrogenases with PQQ cofactors, such as ethanol, methanol, and membrane-bound glucose dehydrogenases, form an 8-bladed beta-propeller.


Pssm-ID: 199835 [Multi-domain]  Cd Length: 529  Bit Score: 44.60  E-value: 1.76e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2730304476 451 PNWSYQ----PEGQLSRDWVVaDSGIYtiqrVEPSQQRIVAVDPTNGEPLWRFDVAADLAAAP--AVTSELV-IYGDV-- 521
Cdd:cd10277    39 PAWSFSfggkQRGQESQPIVN-DGVMY----VTTSYNRVFAIDAKTGKELWKYKHRLPEDIRPccDVVNRGVaLYGDKvy 113

                          90       100
                  ....*....|....*....|...
gi 2730304476 522 ----DNRLVALDAKSGAQLWEGK 540
Cdd:cd10277   114 fgtlDAHLVALDAKTGKVVWKKK 136
PQQ_mGDH cd10280
Membrane-bound PQQ-dependent glucose dehydrogenase; This bacterial subfamily of enzymes ...
 483-534 2.70e-04

Membrane-bound PQQ-dependent glucose dehydrogenase; This bacterial subfamily of enzymes belongs to the dehydrogenase family with pyrroloquinoline quinone (PQQ) as cofactor, and is the only subfamily that is bound to the membrane. Glucose dehydrogenase converts D-glucose to D-glucono-1,5-lactone in a reaction that is coupled with the respiratory chain in the periplasmic oxidation of sugars and alcohols in gram-negative bacteria. Ubiquinone functions as the electron acceptor. The alignment model contains an 8-bladed beta-propeller.


Pssm-ID: 199838 [Multi-domain]  Cd Length: 616  Bit Score: 44.10  E-value: 2.70e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2730304476 483 QRIVAVDPTNGEPLWRFDVAADLAA-----------------APAVTSELVIYGDVDNRLVALDAKSGA 534
Cdd:cd10280    66 NRVIALDAATGKELWRFDPKAGADAapghqtcrgvsywedgaAAAACARRIFFGTGDARLIALDARTGK 134
PQQ_ADH_II cd10279
PQQ_like domain of the quinohemoprotein alcohol dehydrogenase (type II); This family of ...
 480-549 3.48e-04

PQQ_like domain of the quinohemoprotein alcohol dehydrogenase (type II); This family of monomeric and soluble type II alcohol dehydrogenases utilizes pyrroloquinoline quinone (PQQ) as a cofactor and is related to ethanol, methanol, and membrane-bound glucose dehydrogenases. The alignment model contains an 8-bladed beta-propeller.


Pssm-ID: 199837 [Multi-domain]  Cd Length: 549  Bit Score: 43.40  E-value: 3.48e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2730304476 480 PSQQRIVAVDPTNGEPLWRFDVAADLAAAPAVTS-ELVIYGDVDNRLVALDAKSGAQLWEGKTKGRVLTRP 549
Cdd:cd10279   427 ATRGRLVAWDPVTQKAAWRVEHPGPWNGGVLATAgNLVFQGTADGELAAYDARTGEKLWSFDTGSGIVAAP 497
PQQ_2 pfam13360
PQQ-like domain; This domain contains several repeats of the PQQ repeat.
 284-455 5.09e-04

PQQ-like domain; This domain contains several repeats of the PQQ repeat.


Pssm-ID: 433144 [Multi-domain]  Cd Length: 233  Bit Score: 42.00  E-value: 5.09e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2730304476 284 WRVSAASGPARQPVLSDDTLIVH-EKYSLHVLDPES-------RRRYPLIQTNYGGSPAFHGGAAHFPGPGRWLRSVDLR 355
Cdd:pfam13360  57 WRQTLSGEVLGAPLVAGGRVFVVaGDGSLIALDAADgrrlwsyQRSGEPLALRSSGSPAVVGDTVVAGFSSGKLVALDPA 136

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2730304476 356 TGRPR-----RAPRLQVCDGLLG-------VCADILYAPGPDGCLHSIDLPSGEIRWSQSLGkqaiGCAPQATAGNVIIM 423
Cdd:pfam13360 137 TGKVRweaplAAPRGTNELERLVditgtpvVAGGRVFASAYQGRLVAFDAATGRRLWTREIS----GPNGPILDGDLLYV 212

                         170       180       190
                  ....*....|....*....|....*....|..
gi 2730304476 424 AEepqpsnetanrSGGHVVAVLEATGHPNWSY 455
Cdd:pfam13360 213 VS-----------DDGELYALDRATGAVVWKT 233
PQQ pfam01011
PQQ enzyme repeat; The family represent a single repeat of a beta propeller. This propeller ...
 516-549 5.80e-04

PQQ enzyme repeat; The family represent a single repeat of a beta propeller. This propeller has been found in several enzymes which utilize pyrrolo-quinoline quinone as a prosthetic group.


Pssm-ID: 395799 [Multi-domain]  Cd Length: 36  Bit Score: 37.56  E-value: 5.80e-04
                          10        20        30
                  ....*....|....*....|....*....|....
gi 2730304476 516 VIYGDVDNRLVALDAKSGAQLWEGKTKGRVLTRP 549
Cdd:pfam01011   3 VYLGSDDGYLYALDAETGKVLWSFKTGGAVLSSP 36
PRK11138 PRK11138
outer membrane biogenesis protein BamB; Provisional
 386-560 1.03e-03

outer membrane biogenesis protein BamB; Provisional


Pssm-ID: 236857 [Multi-domain]  Cd Length: 394  Bit Score: 41.84  E-value: 1.03e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2730304476 386 GCLHSIDLPSGEIRWS-----QSLGKQAIGcAPQATAGNVIImaeepqpsnETANrsgGHVVAVLEATGHPNWS---YQP 457
Cdd:PRK11138  170 GMLQALNESDGAVKWTvnldvPSLTLRGES-APATAFGGAIV---------GGDN---GRVSAVLMEQGQLIWQqriSQP 236

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2730304476 458 EG--QLSR----DW--VVADSGIYTIQrvepSQQRIVAVDPTNGEPLWRfdvaadlaAAPAVTSELVIYG------DVDN 523
Cdd:PRK11138  237 TGatEIDRlvdvDTtpVVVGGVVYALA----YNGNLVALDLRSGQIVWK--------REYGSVNDFAVDGgriylvDQND 304

                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 2730304476 524 RLVALDAKSGAQLWE-GKTKGRVLTRPFAVGDTLFTAD 560
Cdd:PRK11138  305 RVYALDTRGGVELWSqSDLLHRLLTAPVLYNGYLVVGD 342
PQQ_ADH_II cd10279
PQQ_like domain of the quinohemoprotein alcohol dehydrogenase (type II); This family of ...
 459-541 3.13e-03

PQQ_like domain of the quinohemoprotein alcohol dehydrogenase (type II); This family of monomeric and soluble type II alcohol dehydrogenases utilizes pyrroloquinoline quinone (PQQ) as a cofactor and is related to ethanol, methanol, and membrane-bound glucose dehydrogenases. The alignment model contains an 8-bladed beta-propeller.


Pssm-ID: 199837 [Multi-domain]  Cd Length: 549  Bit Score: 40.32  E-value: 3.13e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2730304476 459 GQLSRDW--------------VVADSGIYTIqrvePSQQRIVAVDPTNGEPLWRFDVAADLAAAPAVTSELV-----IYG 519
Cdd:cd10279    27 GQLGLAWyfdldtnrgqeatpLVVDGVMYVS----GPWSVVYALDARTGKLLWQYDPEVDRESGRKACCDVVnrgvaVWD 102

                          90       100
                  ....*....|....*....|....*...
gi 2730304476 520 DV------DNRLVALDAKSGAQLWEGKT 541
Cdd:cd10279   103 GKvfvgtlDGRLIALDAKTGKEVWSVDT 130
PQQ_MDH cd10278
Large subunit of methanol dehydrogenase (moxF); Methanol dehydrogenase is a key enzyme in the ...
 515-586 6.11e-03

Large subunit of methanol dehydrogenase (moxF); Methanol dehydrogenase is a key enzyme in the utilization of C1 compounds as a source of energy and carbon by bacteria. It catalyzes the oxidation of methanol to formaldehyde, transfering two electrons per methanol to cytochrome c(L) as the acceptor. Methanol dehydrogenase belongs to a family of dehydrogenases with pyrroloquinoline quinone (PQQ) as cofactor, which also includes dehydrogenases specific to other alcohols and membrane-bound glucose dehydrogenases. This alignment model for the large subunit contains an 8-bladed beta-propeller; the functional enzyme forms a heterotetramer composed of two large and two small subunits.


Pssm-ID: 199836 [Multi-domain]  Cd Length: 553  Bit Score: 39.62  E-value: 6.11e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2730304476 515 LVIYGDVDNRLVALDAKSGAQLWEGKT----KGRVLTR-PFAVGDTLFTADRAAT------VTAWKLSVGRKLRSC---- 579
Cdd:cd10278   104 KIFFNQLDGHLVALDAKTGKEVWKVKNgdpkVGETLTMaPLVVKDKVIVGISGGEfgvrgyVTAYDLKTGKLVWRAystg 183

                          90
                  ....*....|
gi 2730304476 580 ---EVLLSPD 586
Cdd:cd10278   184 pdkDVLIGPD 193
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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