NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|2731765778|ref|WP_345772345|]
View 

MULTISPECIES: transposase, partial [unclassified Mammaliicoccus]

Protein Classification

transposase( domain architecture ID 1000873)

IS110 family transposase binds to the end of a transposon and catalyzes the movement of the transposon to another part of the genome by a cut and paste mechanism or a replicative transposition mechanism

Gene Ontology:  GO:0004803|GO:0003677|GO:0006313
PubMed:  16381877|10217489

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
COG3547 super family cl34632
Transposase [Mobilome: prophages, transposons];
3-79 2.89e-12

Transposase [Mobilome: prophages, transposons];


The actual alignment was detected with superfamily member COG3547:

Pssm-ID: 442768 [Multi-domain]  Cd Length: 349  Bit Score: 59.93  E-value: 2.89e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2731765778   3 YLGIDISKrDSVIAHYIDE---KFQKEFTIQNNKNGYNYLLNYLNRVNQPKLI-FESTGIYSRAMVRFCRVNQINYIELN 78
Cdd:COG3547     6 FVGIDVSK-DTFDVAVVDEdgkVVLKVFRFANDRAGLLALLAWLKKLGPPCLVgMEATGGYHHWLARFLAAAGHEVVVVN 84


                  .
gi 2731765778  79 P 79
Cdd:COG3547    85 P 85
 
Name Accession Description Interval E-value
COG3547 COG3547
Transposase [Mobilome: prophages, transposons];
3-79 2.89e-12

Transposase [Mobilome: prophages, transposons];


Pssm-ID: 442768 [Multi-domain]  Cd Length: 349  Bit Score: 59.93  E-value: 2.89e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2731765778   3 YLGIDISKrDSVIAHYIDE---KFQKEFTIQNNKNGYNYLLNYLNRVNQPKLI-FESTGIYSRAMVRFCRVNQINYIELN 78
Cdd:COG3547     6 FVGIDVSK-DTFDVAVVDEdgkVVLKVFRFANDRAGLLALLAWLKKLGPPCLVgMEATGGYHHWLARFLAAAGHEVVVVN 84


                  .
gi 2731765778  79 P 79
Cdd:COG3547    85 P 85
transpos_IS110 NF033542
IS110 family transposase; Proteins of this family are DEDD (Asp, Glu, Asp, Asp) type ...
 3-79 4.57e-07

IS110 family transposase; Proteins of this family are DEDD (Asp, Glu, Asp, Asp) type transposases, which are encoded by the IS110 family elements.


Pssm-ID: 468073 [Multi-domain]  Cd Length: 345  Bit Score: 45.01  E-value: 4.57e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2731765778   3 YLGIDISKRDSVIaHYIDE--KFQKEFTIQNNKNGYNYLLNYLNRVNQPKLI-FESTGIYSRAMVRFCRVNQINYIELNP 79
Cdd:NF033542    1 FVGIDVAKEVFDV-AVVDAsgGEVLRKKFKNTKAGREALLAWLAKLAPPCVVvMEATGGYHAWLRELLALGGFPVVLVNP 79
DEDD_Tnp_IS110 pfam01548
Transposase; Transposase proteins are necessary for efficient DNA transposition. This family ...
 4-79 6.32e-05

Transposase; Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.


Pssm-ID: 460249  Cd Length: 155  Bit Score: 38.36  E-value: 6.32e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2731765778   4 LGIDISKRDSViAHYIDE--KFQKEFTIQNNKNGYNYLLNYLNRVNQPKLI-FESTGIYSRAMVRFCRVNQINYIELNP 79
Cdd:pfam01548   1 VGIDVAKKHHH-ACVIDPdgKVLLSRRFPNDEEGLRALLAKLLASAGEVLVgVEATGHYGALLVAFLLAAGFQVVYVNP 78
 
Name Accession Description Interval E-value
COG3547 COG3547
Transposase [Mobilome: prophages, transposons];
3-79 2.89e-12

Transposase [Mobilome: prophages, transposons];


Pssm-ID: 442768 [Multi-domain]  Cd Length: 349  Bit Score: 59.93  E-value: 2.89e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2731765778   3 YLGIDISKrDSVIAHYIDE---KFQKEFTIQNNKNGYNYLLNYLNRVNQPKLI-FESTGIYSRAMVRFCRVNQINYIELN 78
Cdd:COG3547     6 FVGIDVSK-DTFDVAVVDEdgkVVLKVFRFANDRAGLLALLAWLKKLGPPCLVgMEATGGYHHWLARFLAAAGHEVVVVN 84


                  .
gi 2731765778  79 P 79
Cdd:COG3547    85 P 85
transpos_IS110 NF033542
IS110 family transposase; Proteins of this family are DEDD (Asp, Glu, Asp, Asp) type ...
 3-79 4.57e-07

IS110 family transposase; Proteins of this family are DEDD (Asp, Glu, Asp, Asp) type transposases, which are encoded by the IS110 family elements.


Pssm-ID: 468073 [Multi-domain]  Cd Length: 345  Bit Score: 45.01  E-value: 4.57e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2731765778   3 YLGIDISKRDSVIaHYIDE--KFQKEFTIQNNKNGYNYLLNYLNRVNQPKLI-FESTGIYSRAMVRFCRVNQINYIELNP 79
Cdd:NF033542    1 FVGIDVAKEVFDV-AVVDAsgGEVLRKKFKNTKAGREALLAWLAKLAPPCVVvMEATGGYHAWLRELLALGGFPVVLVNP 79
DEDD_Tnp_IS110 pfam01548
Transposase; Transposase proteins are necessary for efficient DNA transposition. This family ...
 4-79 6.32e-05

Transposase; Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.


Pssm-ID: 460249  Cd Length: 155  Bit Score: 38.36  E-value: 6.32e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2731765778   4 LGIDISKRDSViAHYIDE--KFQKEFTIQNNKNGYNYLLNYLNRVNQPKLI-FESTGIYSRAMVRFCRVNQINYIELNP 79
Cdd:pfam01548   1 VGIDVAKKHHH-ACVIDPdgKVLLSRRFPNDEEGLRALLAKLLASAGEVLVgVEATGHYGALLVAFLLAAGFQVVYVNP 78
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH