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Conserved domains on  [gi|2732033991|ref|WP_345799306|]
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terminase large subunit domain-containing protein [Mycoplana sp. MJR14]

Protein Classification

DNA-packaging protein( domain architecture ID 10009199)

DNA-packaging protein similar to large terminase phage packaging protein, may have ATP-ase activity

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
COG5323 COG5323
Phage large terminase packaging protein [Mobilome: prophages, transposons];
4-413 0e+00

Phage large terminase packaging protein [Mobilome: prophages, transposons];


:

Pssm-ID: 444115 [Multi-domain]  Cd Length: 431  Bit Score: 631.51  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2732033991   4 ERLGRAFRLWAlerHPAQEAPKGDWRVWLLMGGRGSGKTRAGAEWVHDIARRTARL-RIALVAETLGDAREVMIDGVSGI 82
Cdd:COG5323    26 AALPYDWEFWA---RPHQLPPEGDWRTWLILGGRGAGKTRAGAEWVRALAEGAGPArRIALVGETLDDVREVMVEGESGL 102
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2732033991  83 CRIA-RAERPEFEASRRRLVWPNGTIAQIFSSEDPESLRGPQFHLAWCDELGKWRHAQETWDMLQFGLRLGEHPRALVTT 161
Cdd:COG5323   103 LAVHpPDRRPVWEPSRRRLVWPNGAVAQLFSAEDPEALRGPQFDAAWADELAKWRKAEETWDMLQFGLRLGDRPRQVVTT 182
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2732033991 162 TPRAIPLLRALAADRATALERIRTADNAKNLSAGFIDALTERYGGTRLGRQELDGELITDREDALWSRERLEAVRqrfaA 241
Cdd:COG5323   183 TPRPVPLLKRLLADPSTVVTRAPTEANAANLAPSFLEEVRARYAGTRLGRQELDGELLEDVEGALWTRALIEAAR----V 258
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2732033991 242 AQSGPLSRIVVAVDPPAAASARS-CCGIVVAGLDAAGRAVVLADRSVTGASPAGWAGAVVQAFRRFDADRVVAEVNQGGD 320
Cdd:COG5323   259 AEAPPLDRIVVAVDPPASSGKGSdACGIVVAGLREDGRAYVLADASVRGASPAGWARAAVAAYRRHEADRVVAEVNQGGD 338
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2732033991 321 MVGAMLRSIDADLPVTTVRATRGKFLRAEPVAALYEQGRVLHAGAFPELEDQMCDFGPDGLSSGRSPDRLDALVWALTAL 400
Cdd:COG5323   339 MVESVLRQVDPSVPVRLVRATRGKAARAEPVAALYEQGRVRHAGGFPALEDQMCDFTPGGLGGGGSPDRLDALVWALTEL 418
                         410
                  ....*....|...
gi 2732033991 401 VLDRRGEPRVRGI 413
Cdd:COG5323   419 MLGPARRPRVRRL 431
 
Name Accession Description Interval E-value
COG5323 COG5323
Phage large terminase packaging protein [Mobilome: prophages, transposons];
4-413 0e+00

Phage large terminase packaging protein [Mobilome: prophages, transposons];


Pssm-ID: 444115 [Multi-domain]  Cd Length: 431  Bit Score: 631.51  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2732033991   4 ERLGRAFRLWAlerHPAQEAPKGDWRVWLLMGGRGSGKTRAGAEWVHDIARRTARL-RIALVAETLGDAREVMIDGVSGI 82
Cdd:COG5323    26 AALPYDWEFWA---RPHQLPPEGDWRTWLILGGRGAGKTRAGAEWVRALAEGAGPArRIALVGETLDDVREVMVEGESGL 102
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2732033991  83 CRIA-RAERPEFEASRRRLVWPNGTIAQIFSSEDPESLRGPQFHLAWCDELGKWRHAQETWDMLQFGLRLGEHPRALVTT 161
Cdd:COG5323   103 LAVHpPDRRPVWEPSRRRLVWPNGAVAQLFSAEDPEALRGPQFDAAWADELAKWRKAEETWDMLQFGLRLGDRPRQVVTT 182
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2732033991 162 TPRAIPLLRALAADRATALERIRTADNAKNLSAGFIDALTERYGGTRLGRQELDGELITDREDALWSRERLEAVRqrfaA 241
Cdd:COG5323   183 TPRPVPLLKRLLADPSTVVTRAPTEANAANLAPSFLEEVRARYAGTRLGRQELDGELLEDVEGALWTRALIEAAR----V 258
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2732033991 242 AQSGPLSRIVVAVDPPAAASARS-CCGIVVAGLDAAGRAVVLADRSVTGASPAGWAGAVVQAFRRFDADRVVAEVNQGGD 320
Cdd:COG5323   259 AEAPPLDRIVVAVDPPASSGKGSdACGIVVAGLREDGRAYVLADASVRGASPAGWARAAVAAYRRHEADRVVAEVNQGGD 338
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2732033991 321 MVGAMLRSIDADLPVTTVRATRGKFLRAEPVAALYEQGRVLHAGAFPELEDQMCDFGPDGLSSGRSPDRLDALVWALTAL 400
Cdd:COG5323   339 MVESVLRQVDPSVPVRLVRATRGKAARAEPVAALYEQGRVRHAGGFPALEDQMCDFTPGGLGGGGSPDRLDALVWALTEL 418
                         410
                  ....*....|...
gi 2732033991 401 VLDRRGEPRVRGI 413
Cdd:COG5323   419 MLGPARRPRVRRL 431
Terminase_6N pfam03237
Terminase large subunit, T4likevirus-type, N-terminal; This entry represents the N-terminal ...
33-233 9.89e-30

Terminase large subunit, T4likevirus-type, N-terminal; This entry represents the N-terminal domain of terminase large subunits found in a variety of the Caudovirales and prophage regions of bacterial genomes. It includes the terminase large subunit of Bacteriophage T4 (terminase gene 17, Gp17). homologs are also found in Gene Transfer Agents (GTA), including ORFg2 (RCAP_rcc01683) of the GTA of Rhodobacter capsulatus (Rhodopseudomonas capsulata).


Pssm-ID: 427210 [Multi-domain]  Cd Length: 214  Bit Score: 114.44  E-value: 9.89e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2732033991  33 LMGGRGSGKTRAGAEW-VHDIARRtARLRIALVAETLGDAREVMIDGVSGICRIARAE-RPEFEASRR-RLVWPNGTIAQ 109
Cdd:pfam03237   1 ILGGRQSGKTFAGARElLRHALGR-GPENQIILSASKGQAREEGGEFPKGIIELARDLlDPDFEESNKgSIVLSNGASLH 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2732033991 110 IFSSE--DPESLRGPQFHLAWCDELGKWRHAQETWDMLQFGLRLGEHPRALVTTTPRAIPLL-----RALAADRATALER 182
Cdd:pfam03237  80 FLSLNasTAGGYRGAQIDAIYFDEFAWIPKFQESWKVTRLRATLGTDTKTFITTPPTPLHGVydfwtGWLEEKGPPSYVK 159
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2732033991 183 IR-----TADNAKNLSAGFIDALTERYGGTRLgRQELDGELItDREDALWSRERLE 233
Cdd:pfam03237 160 IPatveaTIEDAVKLGEDLIEELEALYSPDEF-AQLLLGEFI-DTSGSIFPRSWLT 213
 
Name Accession Description Interval E-value
COG5323 COG5323
Phage large terminase packaging protein [Mobilome: prophages, transposons];
4-413 0e+00

Phage large terminase packaging protein [Mobilome: prophages, transposons];


Pssm-ID: 444115 [Multi-domain]  Cd Length: 431  Bit Score: 631.51  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2732033991   4 ERLGRAFRLWAlerHPAQEAPKGDWRVWLLMGGRGSGKTRAGAEWVHDIARRTARL-RIALVAETLGDAREVMIDGVSGI 82
Cdd:COG5323    26 AALPYDWEFWA---RPHQLPPEGDWRTWLILGGRGAGKTRAGAEWVRALAEGAGPArRIALVGETLDDVREVMVEGESGL 102
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2732033991  83 CRIA-RAERPEFEASRRRLVWPNGTIAQIFSSEDPESLRGPQFHLAWCDELGKWRHAQETWDMLQFGLRLGEHPRALVTT 161
Cdd:COG5323   103 LAVHpPDRRPVWEPSRRRLVWPNGAVAQLFSAEDPEALRGPQFDAAWADELAKWRKAEETWDMLQFGLRLGDRPRQVVTT 182
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2732033991 162 TPRAIPLLRALAADRATALERIRTADNAKNLSAGFIDALTERYGGTRLGRQELDGELITDREDALWSRERLEAVRqrfaA 241
Cdd:COG5323   183 TPRPVPLLKRLLADPSTVVTRAPTEANAANLAPSFLEEVRARYAGTRLGRQELDGELLEDVEGALWTRALIEAAR----V 258
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2732033991 242 AQSGPLSRIVVAVDPPAAASARS-CCGIVVAGLDAAGRAVVLADRSVTGASPAGWAGAVVQAFRRFDADRVVAEVNQGGD 320
Cdd:COG5323   259 AEAPPLDRIVVAVDPPASSGKGSdACGIVVAGLREDGRAYVLADASVRGASPAGWARAAVAAYRRHEADRVVAEVNQGGD 338
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2732033991 321 MVGAMLRSIDADLPVTTVRATRGKFLRAEPVAALYEQGRVLHAGAFPELEDQMCDFGPDGLSSGRSPDRLDALVWALTAL 400
Cdd:COG5323   339 MVESVLRQVDPSVPVRLVRATRGKAARAEPVAALYEQGRVRHAGGFPALEDQMCDFTPGGLGGGGSPDRLDALVWALTEL 418
                         410
                  ....*....|...
gi 2732033991 401 VLDRRGEPRVRGI 413
Cdd:COG5323   419 MLGPARRPRVRRL 431
Terminase_6N pfam03237
Terminase large subunit, T4likevirus-type, N-terminal; This entry represents the N-terminal ...
33-233 9.89e-30

Terminase large subunit, T4likevirus-type, N-terminal; This entry represents the N-terminal domain of terminase large subunits found in a variety of the Caudovirales and prophage regions of bacterial genomes. It includes the terminase large subunit of Bacteriophage T4 (terminase gene 17, Gp17). homologs are also found in Gene Transfer Agents (GTA), including ORFg2 (RCAP_rcc01683) of the GTA of Rhodobacter capsulatus (Rhodopseudomonas capsulata).


Pssm-ID: 427210 [Multi-domain]  Cd Length: 214  Bit Score: 114.44  E-value: 9.89e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2732033991  33 LMGGRGSGKTRAGAEW-VHDIARRtARLRIALVAETLGDAREVMIDGVSGICRIARAE-RPEFEASRR-RLVWPNGTIAQ 109
Cdd:pfam03237   1 ILGGRQSGKTFAGARElLRHALGR-GPENQIILSASKGQAREEGGEFPKGIIELARDLlDPDFEESNKgSIVLSNGASLH 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2732033991 110 IFSSE--DPESLRGPQFHLAWCDELGKWRHAQETWDMLQFGLRLGEHPRALVTTTPRAIPLL-----RALAADRATALER 182
Cdd:pfam03237  80 FLSLNasTAGGYRGAQIDAIYFDEFAWIPKFQESWKVTRLRATLGTDTKTFITTPPTPLHGVydfwtGWLEEKGPPSYVK 159
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2732033991 183 IR-----TADNAKNLSAGFIDALTERYGGTRLgRQELDGELItDREDALWSRERLE 233
Cdd:pfam03237 160 IPatveaTIEDAVKLGEDLIEELEALYSPDEF-AQLLLGEFI-DTSGSIFPRSWLT 213
Terminase_6C pfam17289
Terminase RNaseH-like domain;
252-400 2.39e-24

Terminase RNaseH-like domain;


Pssm-ID: 435843 [Multi-domain]  Cd Length: 154  Bit Score: 97.84  E-value: 2.39e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2732033991 252 VAVDPPAAASARSCCGIVVAGLDAAGRavVLADRSVTGASPAGWAGAVVQAFRRFDADRVVAEVNQGGDMVGAMLRS-ID 330
Cdd:pfam17289   1 IGVDPAASVGGDYAAIVVIDVDGDKFY--LLAREQERGNSPALQAAAIKKLAERYNVIYIYIDGTGGGESVAELLKRaFP 78
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2732033991 331 ADLPVTTVRATRGKFLRAEPVAALYEQGRVLHAG------AFPELEDQMCDFGPDGLSSGRSPDRLDALVWALTAL 400
Cdd:pfam17289  79 SAFAVRPEPATKGKTARVLKVNDLIESGRLKVDKgpdcanSFNALEKYHTDSGMERSISTTHDDLADALRYALLML 154
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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