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Conserved domains on  [gi|2733280473|ref|WP_346098196|]
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SMP-30/gluconolactonase/LRE family protein, partial [Pseudomonas veronii]

Protein Classification

SMP-30/gluconolactonase/LRE family protein( domain architecture ID 11465288)

SMP-30/gluconolactonase/LRE family protein similar to Staphylococcus lactonase drp35 and Zymomonas mobilis gluconolactonase, which hydrolyzes the gluconolactone formed by glucose-fructose oxidoreductase to form gluconate;

CATH:  2.120.10.30
EC:  3.1.1.-
Gene Ontology:  GO:0005515|GO:0046872|GO:0016787
PubMed:  9868369
SCOP:  4003251

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
YvrE COG3386
Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]; Sugar lactone lactonase ...
 12-164 6.62e-39

Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]; Sugar lactone lactonase YvrE is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway


:

Pssm-ID: 442613 [Multi-domain]  Cd Length: 266  Bit Score: 133.09  E-value: 6.62e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2733280473  12 GFWFHCSPNPKVTRVIEDLAGPNGLCFSPDEKTLYIVEGRAkpnRLVWAYAVNEDGTLGNRNKHIEAT-AYGALDGIKCD 90
Cdd:COG3386   118 GALYRVDPDGSLRVLADGLTFPNGIAFSPDGRTLYVADTGA---GRIYRFDLDADGTLGNRRVFADLPdGPGGPDGLAVD 194

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2733280473  91 EAGNLWCGWGSNGspqgkpeeldGVRVFNAQGKAIGHISLPER-CANLCFGGVQGNRLFMASSHS------IYSVFVNTR 163
Cdd:COG3386   195 ADGNLWVALWGGG----------GVVRFDPDGELLGRIELPERrPTNVAFGGPDLRTLYVTTARSlplagaLFRVRVDVP 264


                  .
gi 2733280473 164 G 164
Cdd:COG3386   265 G 265
 
Name Accession Description Interval E-value
YvrE COG3386
Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]; Sugar lactone lactonase ...
 12-164 6.62e-39

Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]; Sugar lactone lactonase YvrE is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway


Pssm-ID: 442613 [Multi-domain]  Cd Length: 266  Bit Score: 133.09  E-value: 6.62e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2733280473  12 GFWFHCSPNPKVTRVIEDLAGPNGLCFSPDEKTLYIVEGRAkpnRLVWAYAVNEDGTLGNRNKHIEAT-AYGALDGIKCD 90
Cdd:COG3386   118 GALYRVDPDGSLRVLADGLTFPNGIAFSPDGRTLYVADTGA---GRIYRFDLDADGTLGNRRVFADLPdGPGGPDGLAVD 194

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2733280473  91 EAGNLWCGWGSNGspqgkpeeldGVRVFNAQGKAIGHISLPER-CANLCFGGVQGNRLFMASSHS------IYSVFVNTR 163
Cdd:COG3386   195 ADGNLWVALWGGG----------GVVRFDPDGELLGRIELPERrPTNVAFGGPDLRTLYVTTARSlplagaLFRVRVDVP 264


                  .
gi 2733280473 164 G 164
Cdd:COG3386   265 G 265
SGL pfam08450
SMP-30/Gluconolactonase/LRE-like region; This family describes a region that is found in ...
 18-153 5.80e-31

SMP-30/Gluconolactonase/LRE-like region; This family describes a region that is found in proteins expressed by a variety of eukaryotic and prokaryotic species. These proteins include various enzymes, such as senescence marker protein 30 (SMP-30), gluconolactonase and luciferin-regenerating enzyme (LRE). SMP-30 is known to hydrolyse diisopropyl phosphorofluoridate in the liver, and has been noted as having sequence similarity, in the region described in this family, with PON1 and LRE.


Pssm-ID: 462480 [Multi-domain]  Cd Length: 246  Bit Score: 111.97  E-value: 5.80e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2733280473  18 SPNPKVTRVIEDLAGPNGLCFSPDEKTLYIVEGrakPNRLVWAYAVN-EDGTLGNRNKHIEATAY-GALDGIKCDEAGNL 95
Cdd:pfam08450 121 DPDGKLTRVLDGLTISNGLAWSPDGRTLYFADS---PARKIWAYDYDlDGGLISNRRVFADFKPGlGRPDGMAVDAEGNV 197

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2733280473  96 WCGWGSNGspqgkpeeldGVRVFNAQGKAIGHISLPE-RCANLCFGGVQGNRLFMASSH 153
Cdd:pfam08450 198 WVARWGGG----------KVVRFDPDGKLLREIELPAkRPTSCAFGGPDLRTLYVTSAR 246
 
Name Accession Description Interval E-value
YvrE COG3386
Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]; Sugar lactone lactonase ...
 12-164 6.62e-39

Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]; Sugar lactone lactonase YvrE is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway


Pssm-ID: 442613 [Multi-domain]  Cd Length: 266  Bit Score: 133.09  E-value: 6.62e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2733280473  12 GFWFHCSPNPKVTRVIEDLAGPNGLCFSPDEKTLYIVEGRAkpnRLVWAYAVNEDGTLGNRNKHIEAT-AYGALDGIKCD 90
Cdd:COG3386   118 GALYRVDPDGSLRVLADGLTFPNGIAFSPDGRTLYVADTGA---GRIYRFDLDADGTLGNRRVFADLPdGPGGPDGLAVD 194

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2733280473  91 EAGNLWCGWGSNGspqgkpeeldGVRVFNAQGKAIGHISLPER-CANLCFGGVQGNRLFMASSHS------IYSVFVNTR 163
Cdd:COG3386   195 ADGNLWVALWGGG----------GVVRFDPDGELLGRIELPERrPTNVAFGGPDLRTLYVTTARSlplagaLFRVRVDVP 264


                  .
gi 2733280473 164 G 164
Cdd:COG3386   265 G 265
SGL pfam08450
SMP-30/Gluconolactonase/LRE-like region; This family describes a region that is found in ...
 18-153 5.80e-31

SMP-30/Gluconolactonase/LRE-like region; This family describes a region that is found in proteins expressed by a variety of eukaryotic and prokaryotic species. These proteins include various enzymes, such as senescence marker protein 30 (SMP-30), gluconolactonase and luciferin-regenerating enzyme (LRE). SMP-30 is known to hydrolyse diisopropyl phosphorofluoridate in the liver, and has been noted as having sequence similarity, in the region described in this family, with PON1 and LRE.


Pssm-ID: 462480 [Multi-domain]  Cd Length: 246  Bit Score: 111.97  E-value: 5.80e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2733280473  18 SPNPKVTRVIEDLAGPNGLCFSPDEKTLYIVEGrakPNRLVWAYAVN-EDGTLGNRNKHIEATAY-GALDGIKCDEAGNL 95
Cdd:pfam08450 121 DPDGKLTRVLDGLTISNGLAWSPDGRTLYFADS---PARKIWAYDYDlDGGLISNRRVFADFKPGlGRPDGMAVDAEGNV 197

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2733280473  96 WCGWGSNGspqgkpeeldGVRVFNAQGKAIGHISLPE-RCANLCFGGVQGNRLFMASSH 153
Cdd:pfam08450 198 WVARWGGG----------KVVRFDPDGKLLREIELPAkRPTSCAFGGPDLRTLYVTSAR 246
Str_synth pfam03088
Strictosidine synthase; Strictosidine synthase (E.C. 4.3.3.2) is a key enzyme in alkaloid ...
 15-49 5.26e-03

Strictosidine synthase; Strictosidine synthase (E.C. 4.3.3.2) is a key enzyme in alkaloid biosynthesis. It catalyzes the condensation of tryptamine with secologanin to form strictosidine.


Pssm-ID: 281131 [Multi-domain]  Cd Length: 89  Bit Score: 34.72  E-value: 5.26e-03
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 2733280473  15 FHCSPNPKVTRVI-EDLAGPNGLCFSPDEKTLYIVE 49
Cdd:pfam03088  40 MKYDPTTKVTKVLlDDLYFPNGIALSPDGSFVLFCE 75
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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