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Conserved domains on  [gi|2747540856|ref|WP_350634070|]
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IS200/IS605 family transposase, partial [Pseudoalteromonas sp. 2-MNA-CIBAN-0060]

Protein Classification

IS200/IS605 family transposase( domain architecture ID 10485079)

IS200/IS605 family transposase transposase binds to the end of a transposon and catalyzes the movement of the transposon to another part of the genome by a cut and paste mechanism or a replicative transposition mechanism

CATH:  3.30.70.1290
Gene Ontology:  GO:0004803|GO:0003677|GO:0006313|GO:0032196|GO:0015074|GO:0006310
PubMed:  16209952|20215432|18243097|11774877
SCOP:  4003718

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Y1_Tnp pfam01797
Transposase IS200 like; Transposases are needed for efficient transposition of the insertion ...
 1-80 4.09e-29

Transposase IS200 like; Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS200 from E. coli.


:

Pssm-ID: 460334  Cd Length: 119  Bit Score: 99.94  E-value: 4.09e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2747540856   1 YHLVLVTKYRHRCITPEVAAYLESQYKRLLKSWDCELLECNGEPDHLHLLISANPKMQPSKMVNSLKTATSRLVRKEFSE 80
Cdd:pfam01797   7 YHLVWVTKYRRKVLTGEVEERLKEIIREIAKEYGIEILEFNGMPDHVHLLVSAPPKLSISKIVNALKGVSSRRINKEFPE 86
 
Name Accession Description Interval E-value
Y1_Tnp pfam01797
Transposase IS200 like; Transposases are needed for efficient transposition of the insertion ...
 1-80 4.09e-29

Transposase IS200 like; Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS200 from E. coli.


Pssm-ID: 460334  Cd Length: 119  Bit Score: 99.94  E-value: 4.09e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2747540856   1 YHLVLVTKYRHRCITPEVAAYLESQYKRLLKSWDCELLECNGEPDHLHLLISANPKMQPSKMVNSLKTATSRLVRKEFSE 80
Cdd:pfam01797   7 YHLVWVTKYRRKVLTGEVEERLKEIIREIAKEYGIEILEFNGMPDHVHLLVSAPPKLSISKIVNALKGVSSRRINKEFPE 86
transpos_IS200 NF033573
IS200/IS605 family transposase; Most IS200/IS605 family insertion sequences encode both this ...
 1-80 2.53e-27

IS200/IS605 family transposase; Most IS200/IS605 family insertion sequences encode both this transposase, TnpA, about 130 amino acids long, and larger accessory protein, TnpB, that may act as a methyltransferase.


Pssm-ID: 468092  Cd Length: 126  Bit Score: 95.66  E-value: 2.53e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2747540856   1 YHLVLVTKYRHRCITPEVAAYLESQYKRLLKSWDCELLECNGEPDHLHLLISANPKMQPSKMVNSLKTATSRLVRKEFSE 80
Cdd:NF033573   13 YHLVWVPKYRRKVLTGEVEERLKEILREICEEKGVEILELEVDPDHVHLLVSYPPKLSPSKLVNALKGKSSRRLFKEFPE 92
RAYT COG1943
REP element-mobilizing transposase RayT [Mobilome: prophages, transposons];
1-78 1.25e-22

REP element-mobilizing transposase RayT [Mobilome: prophages, transposons];


Pssm-ID: 441546  Cd Length: 138  Bit Score: 84.19  E-value: 1.25e-22
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2747540856   1 YHLVLVTKYRHRCIT-PEVAAYLESQYKRLLKSWDCELLECNGEPDHLHLLISANPKMQPSKMVNSLKTATSRLVRKEF 78
Cdd:COG1943    14 YHITFRTKYRRPVFTdDEDRERLLELLREIAERYGVEILAYVLMPDHVHLLVTLPPDLSLSKIMRRLKGRSSRRINRRY 92
 
Name Accession Description Interval E-value
Y1_Tnp pfam01797
Transposase IS200 like; Transposases are needed for efficient transposition of the insertion ...
 1-80 4.09e-29

Transposase IS200 like; Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS200 from E. coli.


Pssm-ID: 460334  Cd Length: 119  Bit Score: 99.94  E-value: 4.09e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2747540856   1 YHLVLVTKYRHRCITPEVAAYLESQYKRLLKSWDCELLECNGEPDHLHLLISANPKMQPSKMVNSLKTATSRLVRKEFSE 80
Cdd:pfam01797   7 YHLVWVTKYRRKVLTGEVEERLKEIIREIAKEYGIEILEFNGMPDHVHLLVSAPPKLSISKIVNALKGVSSRRINKEFPE 86
transpos_IS200 NF033573
IS200/IS605 family transposase; Most IS200/IS605 family insertion sequences encode both this ...
 1-80 2.53e-27

IS200/IS605 family transposase; Most IS200/IS605 family insertion sequences encode both this transposase, TnpA, about 130 amino acids long, and larger accessory protein, TnpB, that may act as a methyltransferase.


Pssm-ID: 468092  Cd Length: 126  Bit Score: 95.66  E-value: 2.53e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2747540856   1 YHLVLVTKYRHRCITPEVAAYLESQYKRLLKSWDCELLECNGEPDHLHLLISANPKMQPSKMVNSLKTATSRLVRKEFSE 80
Cdd:NF033573   13 YHLVWVPKYRRKVLTGEVEERLKEILREICEEKGVEILELEVDPDHVHLLVSYPPKLSPSKLVNALKGKSSRRLFKEFPE 92
RAYT COG1943
REP element-mobilizing transposase RayT [Mobilome: prophages, transposons];
1-78 1.25e-22

REP element-mobilizing transposase RayT [Mobilome: prophages, transposons];


Pssm-ID: 441546  Cd Length: 138  Bit Score: 84.19  E-value: 1.25e-22
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2747540856   1 YHLVLVTKYRHRCIT-PEVAAYLESQYKRLLKSWDCELLECNGEPDHLHLLISANPKMQPSKMVNSLKTATSRLVRKEF 78
Cdd:COG1943    14 YHITFRTKYRRPVFTdDEDRERLLELLREIAERYGVEILAYVLMPDHVHLLVTLPPDLSLSKIMRRLKGRSSRRINRRY 92
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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