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Conserved domains on  [gi|2765173264|ref|WP_362310456|]
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IS3 family transposase [Streptomyces sp. NPDC039016]

Protein Classification

transposase family protein( domain architecture ID 1750059)

transposase family protein might bind to the end of a transposon and catalyze the movement of the transposon to another part of the genome by a cut and paste mechanism or a replicative transposition mechanism

Gene Ontology:  GO:0003677|GO:0006313
PubMed:  11774877

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
transpos_IS3 NF033516
IS3 family transposase;
9-382 6.53e-121

IS3 family transposase;


:

Pssm-ID: 468052 [Multi-domain]  Cd Length: 369  Bit Score: 354.56  E-value: 6.53e-121
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2765173264   9 EFRADAVALYHASpGGTYASVAKDLGVNHETLRTWV-----GDAKRAAQPGAGEATAMEKENRQLRARVKELELEREILR 83
Cdd:NF033516    1 EFKLEAVREVLEG-GKSVAEVARELGISPSTLYRWRkkyrgGGEAADAGRLKELLTPEEEENRRLKRELAELRLENEILK 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2765173264  84 RAAKYFGgrdqLVSRFQFVDDHRGAFGVKRLCRILTVSRSGFYRWLAGANARAERARAdaELAERIAEIHTESDGTYGAP 163
Cdd:NF033516   80 KARKLLR----PAVKYALIDALRGEYSVRRACRVLGVSRSTYYYWRKRPPSRRAPDDA--ELRARIREIFEESRGRYGYR 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2765173264 164 RMTAELRDEGERVNHKRVARVMRKFNIVGLHLRK-KVRTTIPEPAATRVPDLLQRDFTATTPNTRYVGDITYLPIGDGkF 242
Cdd:NF033516  154 RITALLRREGIRVNHKRVYRLMRELGLLARRRRKrRPYTTDSGHVHPVAPNLLNRQFTATRPNQVWVTDITYIRTAEG-W 232

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2765173264 243 LYLATVLDLCSKRLAGWSIADHMRTSLVTDalKAAAAARGAGGLHGAIFHSDNGAQYVSKEFAQVCENLGVIRSRGAVGT 322
Cdd:NF033516  233 LYLAVVLDLFSREIVGWSVSTSMSAELVLD--ALEMAIEWRGKPEGLILHSDNGSQYTSKAYREWLKEHGITQSMSRPGN 310

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2765173264 323 SADNAAAESLNASLKRETLQGkKRWNGAREARLAVFRWATRYNTRRRHSRLGQISPIAFE 382
Cdd:NF033516  311 CWDNAVAESFFGTLKRECLYR-RRFRTLEEARQAIEEYIEFYNHERPHSSLGYLTPAEFE 369
 
Name Accession Description Interval E-value
transpos_IS3 NF033516
IS3 family transposase;
9-382 6.53e-121

IS3 family transposase;


Pssm-ID: 468052 [Multi-domain]  Cd Length: 369  Bit Score: 354.56  E-value: 6.53e-121
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2765173264   9 EFRADAVALYHASpGGTYASVAKDLGVNHETLRTWV-----GDAKRAAQPGAGEATAMEKENRQLRARVKELELEREILR 83
Cdd:NF033516    1 EFKLEAVREVLEG-GKSVAEVARELGISPSTLYRWRkkyrgGGEAADAGRLKELLTPEEEENRRLKRELAELRLENEILK 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2765173264  84 RAAKYFGgrdqLVSRFQFVDDHRGAFGVKRLCRILTVSRSGFYRWLAGANARAERARAdaELAERIAEIHTESDGTYGAP 163
Cdd:NF033516   80 KARKLLR----PAVKYALIDALRGEYSVRRACRVLGVSRSTYYYWRKRPPSRRAPDDA--ELRARIREIFEESRGRYGYR 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2765173264 164 RMTAELRDEGERVNHKRVARVMRKFNIVGLHLRK-KVRTTIPEPAATRVPDLLQRDFTATTPNTRYVGDITYLPIGDGkF 242
Cdd:NF033516  154 RITALLRREGIRVNHKRVYRLMRELGLLARRRRKrRPYTTDSGHVHPVAPNLLNRQFTATRPNQVWVTDITYIRTAEG-W 232

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2765173264 243 LYLATVLDLCSKRLAGWSIADHMRTSLVTDalKAAAAARGAGGLHGAIFHSDNGAQYVSKEFAQVCENLGVIRSRGAVGT 322
Cdd:NF033516  233 LYLAVVLDLFSREIVGWSVSTSMSAELVLD--ALEMAIEWRGKPEGLILHSDNGSQYTSKAYREWLKEHGITQSMSRPGN 310

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2765173264 323 SADNAAAESLNASLKRETLQGkKRWNGAREARLAVFRWATRYNTRRRHSRLGQISPIAFE 382
Cdd:NF033516  311 CWDNAVAESFFGTLKRECLYR-RRFRTLEEARQAIEEYIEFYNHERPHSSLGYLTPAEFE 369
Tra5 COG2801
Transposase InsO and inactivated derivatives [Mobilome: prophages, transposons];
61-389 1.98e-78

Transposase InsO and inactivated derivatives [Mobilome: prophages, transposons];


Pssm-ID: 442053 [Multi-domain]  Cd Length: 309  Bit Score: 244.29  E-value: 1.98e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2765173264  61 MEKENRQLRARVKELELEREILRRAAKYFGGRDQLVSRFQFVDDHRGAFGVKRLCRILTVSRSGFyrwlaganaraeRAR 140
Cdd:COG2801     1 ELAEEEELRKEEELLRRLLLLLRLLLLRRRVLRRVSRRRRRLLRLLRRRRARSRRRRRLRRPRSY------------RAD 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2765173264 141 ADAELAERIAEIHTESdGTYGAPRMTAELRDEGERVNHKRVARVMRKFNIVGLHLRKKVRTTIPEPAATRVPDLLqrdFT 220
Cdd:COG2801    69 EDAELLERIKEIFAES-PRYGYRRITAELRREGIAVNRKRVRRLMRELGLQARRRRKKKYTTYSGHGGPIAPNLL---FT 144

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2765173264 221 ATTPNTRYVGDITYLPIGDGkFLYLATVLDLCSKRLAGWSIADHMRTSLVTDALKAAAAARGAGGLHgaIFHSDNGAQYV 300
Cdd:COG2801   145 ATAPNQVWVTDITYIPTAEG-WLYLAAVIDLFSREIVGWSVSDSMDAELVVDALEMAIERRGPPKPL--ILHSDNGSQYT 221

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2765173264 301 SKEFAQVCENLGVIRSRGAVGTSADNAAAESLNASLKRETLQGkKRWNGAREARLAVFRWATRYNTRRRHSRLGQISPIA 380
Cdd:COG2801   222 SKAYQELLKKLGITQSMSRPGNPQDNAFIESFFGTLKYELLYR-RRFESLEEAREAIEEYIEFYNHERPHSSLGYLTPAE 300


                  ....*....
gi 2765173264 381 FEQRSTTLA 389
Cdd:COG2801   301 YEKQLAAAA 309
PHA02517 PHA02517
putative transposase OrfB; Reviewed
 118-384 1.74e-50

putative transposase OrfB; Reviewed


Pssm-ID: 222853 [Multi-domain]  Cd Length: 277  Bit Score: 170.82  E-value: 1.74e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2765173264 118 LTVSRSGFYRW---LAGANARAERARADAELAERIAEIHTESDGTYGAPRMTAELRDEGERVNHKRVARVMRKFNIVGLH 194
Cdd:PHA02517    1 LGIAPSTYYRCqqqRHHPDKRRARAQHDDWLKSEILRVYDENHQVYGVRKVWRQLNREGIRVARCTVGRLMKELGLAGVL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2765173264 195 LRKKVRTTIPEPAATRvPDLLQRDFTATTPNTRYVGDITYLPIGDGkFLYLATVLDLCSKRLAGWSIADHMRTSLVTDAL 274
Cdd:PHA02517   81 RGKKVRTTISRKAVAA-PDRVNRQFVATRPNQLWVADFTYVSTWQG-WVYVAFIIDVFARRIVGWRVSSSMDTDFVLDAL 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2765173264 275 KAAAAARGAGGLHgaIFHSDNGAQYVSKEFAQVCENLGVIRSRGAVGTSADNAAAESLNASLKRETLQgKKRWNGAREAR 354
Cdd:PHA02517  159 EQALWARGRPGGL--IHHSDKGSQYVSLAYTQRLKEAGIRASTGSRGDSYDNAPAESINGLYKAEVIH-RVSWKNREEVE 235

                         250       260       270
                  ....*....|....*....|....*....|
gi 2765173264 355 LAVFRWATRYNTRRRHSRLGQISPIAFEQR 384
Cdd:PHA02517  236 LATLEWVAWYNNRRLHERLGYTPPAEAEKA 265
rve pfam00665
Integrase core domain; Integrase mediates integration of a DNA copy of the viral genome into ...
 224-323 1.23e-19

Integrase core domain; Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain pfam00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyzes the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site.


Pssm-ID: 459897 [Multi-domain]  Cd Length: 98  Bit Score: 83.13  E-value: 1.23e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2765173264 224 PNTRYVGDITYLPI-GDGKFLYLATVLDLCSKRLAGWSIADHMRTSLVTDalkAAAAARGAGGLHGAIFHSDNGAQYVSK 302
Cdd:pfam00665   1 PNQLWQGDFTYIRIpGGGGKLYLLVIVDDFSREILAWALSSEMDAELVLD---ALERAIAFRGGVPLIIHSDNGSEYTSK 77

                          90       100
                  ....*....|....*....|.
gi 2765173264 303 EFAQVCENLGVIRSRGAVGTS 323
Cdd:pfam00665  78 AFREFLKDLGIKPSFSRPGNP 98
transpos_IS481 NF033577
IS481 family transposase; null
 111-379 1.75e-12

IS481 family transposase; null


Pssm-ID: 468094 [Multi-domain]  Cd Length: 283  Bit Score: 67.23  E-value: 1.75e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2765173264 111 VKRLCRILTVSRSGFYRWLAGANARAER-------------ARADAELAERIAEIHTESdgTYGAPRMTAELRDEGERVN 177
Cdd:NF033577   16 VREAARRFGISRKTVYKWLKRYRAGGEEglidrsrrphrspRRTSPETEARILALRREL--RLGPRRIAYELERQGPGVS 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2765173264 178 HKRVARVMRKFNIVGL-HLRKKVRTTIP-EPAATrvPDLLQrdftattpntryvGDITYLP-IGDGKFLYLATVLDLCSk 254
Cdd:NF033577   94 RSTVHRILRRHGLSRLrALDRKTGKVKRyERAHP--GELWH-------------IDIKKLGrIPDVGRLYLHTAIDDHS- 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2765173264 255 RLAGWSIADHMRTSLVTDALKAAAAARGAGGLHGAifhSDNGAQYVSK--EFAQVCENLGVIRSRGAVGTSADNAAAESL 332
Cdd:NF033577  158 RFAYAELYPDETAETAADFLRRAFAEHGIPIRRVL---TDNGSEFRSRahGFELALAELGIEHRRTRPYHPQTNGKVERF 234

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*..
gi 2765173264 333 NASLKRETLQGKkRWNGAREARLAVFRWATRYNTRRRHSRLGQISPI 379
Cdd:NF033577  235 HRTLKDEFAYAR-PYESLAELQAALDEWLHHYNHHRPHSALGGKTPA 280
 
Name Accession Description Interval E-value
transpos_IS3 NF033516
IS3 family transposase;
9-382 6.53e-121

IS3 family transposase;


Pssm-ID: 468052 [Multi-domain]  Cd Length: 369  Bit Score: 354.56  E-value: 6.53e-121
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2765173264   9 EFRADAVALYHASpGGTYASVAKDLGVNHETLRTWV-----GDAKRAAQPGAGEATAMEKENRQLRARVKELELEREILR 83
Cdd:NF033516    1 EFKLEAVREVLEG-GKSVAEVARELGISPSTLYRWRkkyrgGGEAADAGRLKELLTPEEEENRRLKRELAELRLENEILK 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2765173264  84 RAAKYFGgrdqLVSRFQFVDDHRGAFGVKRLCRILTVSRSGFYRWLAGANARAERARAdaELAERIAEIHTESDGTYGAP 163
Cdd:NF033516   80 KARKLLR----PAVKYALIDALRGEYSVRRACRVLGVSRSTYYYWRKRPPSRRAPDDA--ELRARIREIFEESRGRYGYR 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2765173264 164 RMTAELRDEGERVNHKRVARVMRKFNIVGLHLRK-KVRTTIPEPAATRVPDLLQRDFTATTPNTRYVGDITYLPIGDGkF 242
Cdd:NF033516  154 RITALLRREGIRVNHKRVYRLMRELGLLARRRRKrRPYTTDSGHVHPVAPNLLNRQFTATRPNQVWVTDITYIRTAEG-W 232

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2765173264 243 LYLATVLDLCSKRLAGWSIADHMRTSLVTDalKAAAAARGAGGLHGAIFHSDNGAQYVSKEFAQVCENLGVIRSRGAVGT 322
Cdd:NF033516  233 LYLAVVLDLFSREIVGWSVSTSMSAELVLD--ALEMAIEWRGKPEGLILHSDNGSQYTSKAYREWLKEHGITQSMSRPGN 310

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2765173264 323 SADNAAAESLNASLKRETLQGkKRWNGAREARLAVFRWATRYNTRRRHSRLGQISPIAFE 382
Cdd:NF033516  311 CWDNAVAESFFGTLKRECLYR-RRFRTLEEARQAIEEYIEFYNHERPHSSLGYLTPAEFE 369
Tra5 COG2801
Transposase InsO and inactivated derivatives [Mobilome: prophages, transposons];
61-389 1.98e-78

Transposase InsO and inactivated derivatives [Mobilome: prophages, transposons];


Pssm-ID: 442053 [Multi-domain]  Cd Length: 309  Bit Score: 244.29  E-value: 1.98e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2765173264  61 MEKENRQLRARVKELELEREILRRAAKYFGGRDQLVSRFQFVDDHRGAFGVKRLCRILTVSRSGFyrwlaganaraeRAR 140
Cdd:COG2801     1 ELAEEEELRKEEELLRRLLLLLRLLLLRRRVLRRVSRRRRRLLRLLRRRRARSRRRRRLRRPRSY------------RAD 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2765173264 141 ADAELAERIAEIHTESdGTYGAPRMTAELRDEGERVNHKRVARVMRKFNIVGLHLRKKVRTTIPEPAATRVPDLLqrdFT 220
Cdd:COG2801    69 EDAELLERIKEIFAES-PRYGYRRITAELRREGIAVNRKRVRRLMRELGLQARRRRKKKYTTYSGHGGPIAPNLL---FT 144

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2765173264 221 ATTPNTRYVGDITYLPIGDGkFLYLATVLDLCSKRLAGWSIADHMRTSLVTDALKAAAAARGAGGLHgaIFHSDNGAQYV 300
Cdd:COG2801   145 ATAPNQVWVTDITYIPTAEG-WLYLAAVIDLFSREIVGWSVSDSMDAELVVDALEMAIERRGPPKPL--ILHSDNGSQYT 221

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2765173264 301 SKEFAQVCENLGVIRSRGAVGTSADNAAAESLNASLKRETLQGkKRWNGAREARLAVFRWATRYNTRRRHSRLGQISPIA 380
Cdd:COG2801   222 SKAYQELLKKLGITQSMSRPGNPQDNAFIESFFGTLKYELLYR-RRFESLEEAREAIEEYIEFYNHERPHSSLGYLTPAE 300


                  ....*....
gi 2765173264 381 FEQRSTTLA 389
Cdd:COG2801   301 YEKQLAAAA 309
PHA02517 PHA02517
putative transposase OrfB; Reviewed
 118-384 1.74e-50

putative transposase OrfB; Reviewed


Pssm-ID: 222853 [Multi-domain]  Cd Length: 277  Bit Score: 170.82  E-value: 1.74e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2765173264 118 LTVSRSGFYRW---LAGANARAERARADAELAERIAEIHTESDGTYGAPRMTAELRDEGERVNHKRVARVMRKFNIVGLH 194
Cdd:PHA02517    1 LGIAPSTYYRCqqqRHHPDKRRARAQHDDWLKSEILRVYDENHQVYGVRKVWRQLNREGIRVARCTVGRLMKELGLAGVL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2765173264 195 LRKKVRTTIPEPAATRvPDLLQRDFTATTPNTRYVGDITYLPIGDGkFLYLATVLDLCSKRLAGWSIADHMRTSLVTDAL 274
Cdd:PHA02517   81 RGKKVRTTISRKAVAA-PDRVNRQFVATRPNQLWVADFTYVSTWQG-WVYVAFIIDVFARRIVGWRVSSSMDTDFVLDAL 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2765173264 275 KAAAAARGAGGLHgaIFHSDNGAQYVSKEFAQVCENLGVIRSRGAVGTSADNAAAESLNASLKRETLQgKKRWNGAREAR 354
Cdd:PHA02517  159 EQALWARGRPGGL--IHHSDKGSQYVSLAYTQRLKEAGIRASTGSRGDSYDNAPAESINGLYKAEVIH-RVSWKNREEVE 235

                         250       260       270
                  ....*....|....*....|....*....|
gi 2765173264 355 LAVFRWATRYNTRRRHSRLGQISPIAFEQR 384
Cdd:PHA02517  236 LATLEWVAWYNNRRLHERLGYTPPAEAEKA 265
rve pfam00665
Integrase core domain; Integrase mediates integration of a DNA copy of the viral genome into ...
 224-323 1.23e-19

Integrase core domain; Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain pfam00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyzes the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site.


Pssm-ID: 459897 [Multi-domain]  Cd Length: 98  Bit Score: 83.13  E-value: 1.23e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2765173264 224 PNTRYVGDITYLPI-GDGKFLYLATVLDLCSKRLAGWSIADHMRTSLVTDalkAAAAARGAGGLHGAIFHSDNGAQYVSK 302
Cdd:pfam00665   1 PNQLWQGDFTYIRIpGGGGKLYLLVIVDDFSREILAWALSSEMDAELVLD---ALERAIAFRGGVPLIIHSDNGSEYTSK 77

                          90       100
                  ....*....|....*....|.
gi 2765173264 303 EFAQVCENLGVIRSRGAVGTS 323
Cdd:pfam00665  78 AFREFLKDLGIKPSFSRPGNP 98
InsE COG2963
Transposase InsE and inactivated derivatives [Mobilome: prophages, transposons];
5-89 3.50e-19

Transposase InsE and inactivated derivatives [Mobilome: prophages, transposons];


Pssm-ID: 442203 [Multi-domain]  Cd Length: 93  Bit Score: 81.51  E-value: 3.50e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2765173264   5 KYSLEFRADAVALYHaSPGGTYASVAKDLGVNHETLRTWVGDAKRAAQ---PGAGEATAMEKENRQLRARVKELELEREI 81
Cdd:COG2963     7 RYSPEFKAEAVRLVL-EGGASVAEVARELGISPSTLYRWVRQYREGGLggfPGDGRTTPEQAEIRRLRKELRRLEMENDI 85


                  ....*...
gi 2765173264  82 LRRAAKYF 89
Cdd:COG2963    86 LKKAAALL 93
HTH_21 pfam13276
HTH-like domain; This domain contains a predicted helix-turn-helix suggesting a DNA-binding ...
 144-198 4.19e-16

HTH-like domain; This domain contains a predicted helix-turn-helix suggesting a DNA-binding function.


Pssm-ID: 463824 [Multi-domain]  Cd Length: 60  Bit Score: 71.83  E-value: 4.19e-16
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2765173264 144 ELAERIAEIHTESDGTYGAPRMTAELRDEGE-RVNHKRVARVMRKFNIVGLHLRKK 198
Cdd:pfam13276   5 ELLEAIREIFEESRGTYGYRRITAELRREGGiRVNRKRVARLMRELGLRARRRRKR 60
HTH_Tnp_1 pfam01527
Transposase; Transposase proteins are necessary for efficient DNA transposition. This family ...
 2-73 1.25e-12

Transposase; Transposase proteins are necessary for efficient DNA transposition. This family consists of various E. coli insertion elements and other bacterial transposases some of which are members of the IS3 family.


Pssm-ID: 426308 [Multi-domain]  Cd Length: 75  Bit Score: 62.76  E-value: 1.25e-12
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2765173264   2 GTSKYSLEFRADAVALYhASPGGTYASVAKDLGVNHETLRTWVGDAK--RAAQPGAGEATAMEKENRQLRARVK 73
Cdd:pfam01527   3 KRRRFSEEFKLRAVKEV-LEPGRTVKEVARRHGVSPNTLYQWRRQYEggMGASPARPRLTALEEENRRLKRELA 75
transpos_IS481 NF033577
IS481 family transposase; null
 111-379 1.75e-12

IS481 family transposase; null


Pssm-ID: 468094 [Multi-domain]  Cd Length: 283  Bit Score: 67.23  E-value: 1.75e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2765173264 111 VKRLCRILTVSRSGFYRWLAGANARAER-------------ARADAELAERIAEIHTESdgTYGAPRMTAELRDEGERVN 177
Cdd:NF033577   16 VREAARRFGISRKTVYKWLKRYRAGGEEglidrsrrphrspRRTSPETEARILALRREL--RLGPRRIAYELERQGPGVS 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2765173264 178 HKRVARVMRKFNIVGL-HLRKKVRTTIP-EPAATrvPDLLQrdftattpntryvGDITYLP-IGDGKFLYLATVLDLCSk 254
Cdd:NF033577   94 RSTVHRILRRHGLSRLrALDRKTGKVKRyERAHP--GELWH-------------IDIKKLGrIPDVGRLYLHTAIDDHS- 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2765173264 255 RLAGWSIADHMRTSLVTDALKAAAAARGAGGLHGAifhSDNGAQYVSK--EFAQVCENLGVIRSRGAVGTSADNAAAESL 332
Cdd:NF033577  158 RFAYAELYPDETAETAADFLRRAFAEHGIPIRRVL---TDNGSEFRSRahGFELALAELGIEHRRTRPYHPQTNGKVERF 234

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*..
gi 2765173264 333 NASLKRETLQGKkRWNGAREARLAVFRWATRYNTRRRHSRLGQISPI 379
Cdd:NF033577  235 HRTLKDEFAYAR-PYESLAELQAALDEWLHHYNHHRPHSALGGKTPA 280
rve_3 pfam13683
Integrase core domain;
311-378 7.76e-10

Integrase core domain;


Pssm-ID: 433402 [Multi-domain]  Cd Length: 67  Bit Score: 54.53  E-value: 7.76e-10
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2765173264 311 LGVIRSRGAVGTSADNAAAESLNASLKRETLqGKKRWNGAREARLAVFRWATRYNTRRRHSRLGQISP 378
Cdd:pfam13683   1 LGIEISYIAPGKPMQNGLVESFNGTLRDECL-NEHLFSSLAEARALLAAWREDYNTERPHSSLGYRTP 67
PRK09409 PRK09409
IS2 transposase TnpB; Reviewed
 159-378 3.57e-04

IS2 transposase TnpB; Reviewed


Pssm-ID: 181829 [Multi-domain]  Cd Length: 301  Bit Score: 42.01  E-value: 3.57e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2765173264 159 TYGAPRMTAELRDEGE-----RVNHKRVARVMRKfniVGLHLRKKvrttipePAATRVPDLLQRDFTATTPNTRYVGDIT 233
Cdd:PRK09409   65 TYGYRRVWALLRRQAEldgmpAINAKRVYRIMRQ---NALLLERK-------PAVPPSKRAHTGRVAVKESNQRWCSDGF 134

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2765173264 234 YLPIGDGKFLYLATVLDLCSKRLAGWSIAD---HMRTSLVTDALKAAAAARGAGGLHGAIFHSDNGAQYVSKEFAQVCEN 310
Cdd:PRK09409  135 EFCCDNGERLRVTFALDCCDREALHWAVTTggfNSETVQDVMLGAVERRFGNDLPSSPVEWLTDNGSCYRANETRQFARM 214

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2765173264 311 LGVIRSRGAVGTSADNAAAESLNASLKRETLQGKKRWNGAREARlAVFRWATRYNTRRRHSRLGQISP 378
Cdd:PRK09409  215 LGLEPKNTAVRSPESNGIAESFVKTIKRDYISIMPKPDGLTAAK-NLAEAFEHYNEWHPHSALGYRSP 281
PRK14702 PRK14702
insertion element IS2 transposase InsD; Provisional
 159-378 1.04e-03

insertion element IS2 transposase InsD; Provisional


Pssm-ID: 237792 [Multi-domain]  Cd Length: 262  Bit Score: 40.49  E-value: 1.04e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2765173264 159 TYGAPRMTAELRDEGE-----RVNHKRVARVMRKfniVGLHLRKKvrttipePAATRVPDLLQRDFTATTPNTRYVGDIT 233
Cdd:PRK14702   26 TYGYRRVWALLRRQAEldgmpAINAKRVYRLMRQ---NALLLERK-------PAVPPSKRAHTGRVAVKESNQRWCSDGF 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2765173264 234 YLPIGDGKFLYLATVLDLCSKRLAGWSIADH-MRTSLVTDALKAAAAARGAGGLHGAIFH--SDNGAQYVSKEFAQVCEN 310
Cdd:PRK14702   96 EFCCDNGERLRVTFALDCCDREALHWAVTTGgFNSETVQDVMLGAVERRFGNDLPSSPVEwlTDNGSCYRANETRQFARM 175

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2765173264 311 LGVIRSRGAVGTSADNAAAESLNASLKRETLQGKKRWNGAREARlAVFRWATRYNTRRRHSRLGQISP 378
Cdd:PRK14702  176 LGLEPKNTAVRSPESNGIAESFVKTIKRDYISIMPKPDGLTAAK-NLAEAFEHYNEWHPHSALGYRSP 242
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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