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Conserved domains on  [gi|2765360160|ref|WP_362491524|]
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MULTISPECIES: nuclear transport factor 2 family protein [unclassified Streptomyces]

Protein Classification

nuclear transport factor 2 family protein( domain architecture ID 10007626)

nuclear transport factor 2 (NTF2) family protein with a SnoaL-like polyketide cyclase domain

CATH:  3.10.450.50
SCOP:  4001306|3000472

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
YesE COG3631
Ketosteroid isomerase-related protein [General function prediction only];
1-96 6.38e-09

Ketosteroid isomerase-related protein [General function prediction only];


:

Pssm-ID: 442849  Cd Length: 126  Bit Score: 50.31  E-value: 6.38e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2765360160   1 MRAFRAAVEAHDMDAVEALLAEDVVFTSPV--VFKPYRGRAITTAILRAVERVFEDFRYERVIGEEDGRDHALLFSARVG 78
Cdd:COG3631     6 VRRFYAAFNAGDVDALLALLAEDVVWEDPGgpGAGTYRGKEAVRAFFARLAAAFEDLRFEVRRVVADGDRVVVEGTVRGT 85

                          90       100
                  ....*....|....*....|....
gi 2765360160  79 DR------RISGCDFLHLdEDGRI 96
Cdd:COG3631    86 VLatgkpyENRYADVFTV-RDGKI 108
 
Name Accession Description Interval E-value
YesE COG3631
Ketosteroid isomerase-related protein [General function prediction only];
1-96 6.38e-09

Ketosteroid isomerase-related protein [General function prediction only];


Pssm-ID: 442849  Cd Length: 126  Bit Score: 50.31  E-value: 6.38e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2765360160   1 MRAFRAAVEAHDMDAVEALLAEDVVFTSPV--VFKPYRGRAITTAILRAVERVFEDFRYERVIGEEDGRDHALLFSARVG 78
Cdd:COG3631     6 VRRFYAAFNAGDVDALLALLAEDVVWEDPGgpGAGTYRGKEAVRAFFARLAAAFEDLRFEVRRVVADGDRVVVEGTVRGT 85

                          90       100
                  ....*....|....*....|....
gi 2765360160  79 DR------RISGCDFLHLdEDGRI 96
Cdd:COG3631    86 VLatgkpyENRYADVFTV-RDGKI 108
SnoaL_2 pfam12680
SnoaL-like domain; This family contains a large number of proteins that share the SnoaL fold.
 2-96 1.04e-06

SnoaL-like domain; This family contains a large number of proteins that share the SnoaL fold.


Pssm-ID: 432716 [Multi-domain]  Cd Length: 100  Bit Score: 43.81  E-value: 1.04e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2765360160   2 RAFRAAVEAHDMDAVEALLAEDVVFTSPvvFKPYRGRAITTAILRAVERVFEDFRYERVIGEEDGRDHALLFSARVGDR- 80
Cdd:pfam12680   2 RRFYEALNAGDLDALAALFAPDAVFHDP--GGPLRGRDAIRAFFAALFAAFPDLRFEIHDVIADGDRVAVRWTVTGTIPp 79

                          90       100
                  ....*....|....*....|.
gi 2765360160  81 -----RISGCDFLHLdEDGRI 96
Cdd:pfam12680  80 tgrgvRVRGVDVFRF-RDGKI 99
TIGR02096 TIGR02096
conserved hypothetical protein, steroid delta-isomerase-related; This family of proteins about ...
 2-55 8.17e-04

conserved hypothetical protein, steroid delta-isomerase-related; This family of proteins about 135 amino acids in length largely restricted to the Proteobacteria. This family and a delta5-3-ketosteroid isomerase from Pseudomonas testosteroni appear homologous, especially toward their respective N-termini. Members, therefore, probably are enzymes.


Pssm-ID: 273970  Cd Length: 129  Bit Score: 36.97  E-value: 8.17e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2765360160   2 RAFRAAVEAHDMDAVEALLAEDVVFTSPVVFKPYRGRAITTAILRAVERVFEDF 55
Cdd:TIGR02096   5 QHWIEAFNRGDMDAVLALLAEDVLYDDNQGGRVLGGKAQLARFLAPYRTAFPDL 58
PRK08241 PRK08241
RNA polymerase subunit sigma-70;
2-48 1.81e-03

RNA polymerase subunit sigma-70;


Pssm-ID: 236196 [Multi-domain]  Cd Length: 339  Bit Score: 36.84  E-value: 1.81e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 2765360160   2 RAFRAAVEAHDMDAVEALLAEDVVFTSPVVFKPYRGRAITTAILRAV 48
Cdd:PRK08241  221 ARYVAAFEAYDVDALVALLTEDATWSMPPFPLWYRGRDAIAAFLAGQ 267
 
Name Accession Description Interval E-value
YesE COG3631
Ketosteroid isomerase-related protein [General function prediction only];
1-96 6.38e-09

Ketosteroid isomerase-related protein [General function prediction only];


Pssm-ID: 442849  Cd Length: 126  Bit Score: 50.31  E-value: 6.38e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2765360160   1 MRAFRAAVEAHDMDAVEALLAEDVVFTSPV--VFKPYRGRAITTAILRAVERVFEDFRYERVIGEEDGRDHALLFSARVG 78
Cdd:COG3631     6 VRRFYAAFNAGDVDALLALLAEDVVWEDPGgpGAGTYRGKEAVRAFFARLAAAFEDLRFEVRRVVADGDRVVVEGTVRGT 85

                          90       100
                  ....*....|....*....|....
gi 2765360160  79 DR------RISGCDFLHLdEDGRI 96
Cdd:COG3631    86 VLatgkpyENRYADVFTV-RDGKI 108
SnoaL_2 pfam12680
SnoaL-like domain; This family contains a large number of proteins that share the SnoaL fold.
 2-96 1.04e-06

SnoaL-like domain; This family contains a large number of proteins that share the SnoaL fold.


Pssm-ID: 432716 [Multi-domain]  Cd Length: 100  Bit Score: 43.81  E-value: 1.04e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2765360160   2 RAFRAAVEAHDMDAVEALLAEDVVFTSPvvFKPYRGRAITTAILRAVERVFEDFRYERVIGEEDGRDHALLFSARVGDR- 80
Cdd:pfam12680   2 RRFYEALNAGDLDALAALFAPDAVFHDP--GGPLRGRDAIRAFFAALFAAFPDLRFEIHDVIADGDRVAVRWTVTGTIPp 79

                          90       100
                  ....*....|....*....|.
gi 2765360160  81 -----RISGCDFLHLdEDGRI 96
Cdd:pfam12680  80 tgrgvRVRGVDVFRF-RDGKI 99
LimA COG4308
Limonene-1,2-epoxide hydrolase LimA/EphG [Secondary metabolites biosynthesis, transport and ...
 2-67 1.31e-04

Limonene-1,2-epoxide hydrolase LimA/EphG [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443449  Cd Length: 119  Bit Score: 38.74  E-value: 1.31e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2765360160   2 RAFRAAVEAHDMDAVEALLAEDVVFTsPVVFKPYRGRAITTAILRAVERVFEDFRYE-RVIGEEDGR 67
Cdd:COG4308     9 RAFLAAWSRLDVDAALSLLADDAVYH-NVPLPPVRGRDAVRAFLEGFLRGAAGFEVRiHHIAADGGT 74
TIGR02096 TIGR02096
conserved hypothetical protein, steroid delta-isomerase-related; This family of proteins about ...
 2-55 8.17e-04

conserved hypothetical protein, steroid delta-isomerase-related; This family of proteins about 135 amino acids in length largely restricted to the Proteobacteria. This family and a delta5-3-ketosteroid isomerase from Pseudomonas testosteroni appear homologous, especially toward their respective N-termini. Members, therefore, probably are enzymes.


Pssm-ID: 273970  Cd Length: 129  Bit Score: 36.97  E-value: 8.17e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2765360160   2 RAFRAAVEAHDMDAVEALLAEDVVFTSPVVFKPYRGRAITTAILRAVERVFEDF 55
Cdd:TIGR02096   5 QHWIEAFNRGDMDAVLALLAEDVLYDDNQGGRVLGGKAQLARFLAPYRTAFPDL 58
YybH COG4319
Ketosteroid isomerase homolog YybH [General function prediction only];
1-53 9.18e-04

Ketosteroid isomerase homolog YybH [General function prediction only];


Pssm-ID: 443460 [Multi-domain]  Cd Length: 131  Bit Score: 36.66  E-value: 9.18e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2765360160   1 MRAFRAAVEAHDMDAVEALLAEDVVFTSPvVFKPYRGRAittAILRAVERVFE 53
Cdd:COG4319    15 LAAFAEAFNAGDADALAALYAEDAVFFDP-GGPPVRGRE---AIRAAWAAAFA 63
PRK08241 PRK08241
RNA polymerase subunit sigma-70;
2-48 1.81e-03

RNA polymerase subunit sigma-70;


Pssm-ID: 236196 [Multi-domain]  Cd Length: 339  Bit Score: 36.84  E-value: 1.81e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 2765360160   2 RAFRAAVEAHDMDAVEALLAEDVVFTSPVVFKPYRGRAITTAILRAV 48
Cdd:PRK08241  221 ARYVAAFEAYDVDALVALLTEDATWSMPPFPLWYRGRDAIAAFLAGQ 267
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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